Patent International Class: C07H 21/0

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Synthesis and use of anti-reverse phosphorothioate analogs of the messenger RNA cap
Inventor: Jemielity, et al. | Patent Number: 8153773

Compositions and methods for nucleic acid sequencing
Inventor: Travers, et al. | Patent Number: 8153375

Oligonucleotide analogues
Inventor: Wengel, et al. | Patent Number: 8153365

Dynamic and combinatorial synthesis of polymerase primers
Inventor: Benner | Patent Number: 8153361

Detection using a dye and a dye modifier
Inventor: Mao, et al. | Patent Number: 8148515

Methods and compositions for isolating nucleic acid
Inventor: Kelso, et al. | Patent Number: 8148071

Labelled nucleotides
Inventor: Balasubramanian, et al. | Patent Number: 8148064

Method and systems for identifying micro-RNA targets and synthesizing novel micro-RNAs and uses of the same
Inventor: Hatzigeorgiou, et al. | Patent Number: 8145436

Method for bisulfite treatment
Inventor: Markert-Hahn | Patent Number: 8137937

Method for the stabilization of chimeric immunoglobulins or immunoglobulin fragments, and stabilized anti-EGP-2 scFv fragment
Inventor: Pluckthun, et al. | Patent Number: 8137932

Method for the synthesis of DNA fragments
Inventor: Schatz | Patent Number: 8137906

Primer array synthesis and validation
Inventor: Kuimelis, et al. | Patent Number: 8133987

Process for the fermentative preparation of organic chemical compounds using coryneform bacteria in which the SugR gene is present in attenuated form
Inventor: Bathe, et al. | Patent Number: 8133714

Engineered fluorescent dye labeled nucleotide analogs for DNA sequencing
Inventor: Shen, et al. | Patent Number: 8133702

Labeled solid supports for organic synthesis
Inventor: Letuchy, et al. | Patent Number: 8129517

RNA complexes featuring paranemic binding, methods of their production and sensors and analytical methods involving same
Inventor: Leontis, et al. | Patent Number: 8129516

Modified amylases, nucleic acids encoding those amylases and uses thereof
Inventor: Kragh, et al. | Patent Number: 8129511

Method for single-step attachment of a label to target molecules
Inventor: Slattum, et al. | Patent Number: 8129509

Recombinant colwellia psychrerythraea alkaline phosphatase and uses thereof
Inventor: Muller-Greven, et al. | Patent Number: 8129168

Mutations in ion channels
Inventor: Mulley, et al. | Patent Number: 8129142

Bisulfite conversion of DNA
Inventor: Fuhrmann, et al. | Patent Number: 8129107

Method of preparing 5'-amino-linker oligonucleotides derivatives and analogous 5'-labeled-linker oligonucleotides therefrom
Inventor: Lee, et al. | Patent Number: 8124756

Targeted cell death
Inventor: Selkirk, et al. | Patent Number: 8124749

Production of 3-hydroxypropionic acid using beta-alanine/pyruvate aminotransferase
Inventor: Liao, et al. | Patent Number: 8124388

Process and materials for production of glucosamine and N-acetylglucosamine
Inventor: Deng, et al. | Patent Number: 8124381

Methods for covalent linking of optical reporters
Inventor: Kwok, et al. | Patent Number: 8124333

Luminescent metal ion complexes
Inventor: Cook, et al. | Patent Number: 8119781

Anti-MicroRNA oligonucleotide molecules
Inventor: Tuschl, et al. | Patent Number: 8114985

RNAi modulation of Aha and therapeutic uses thereof
Inventor: Constien, et al. | Patent Number: 8114984

Nucleic acid and its use effecting ciliate tetrahymena bifunctional dihydrofolate reductase-thymidylate synthase deficiency
Inventor: Weide, et al. | Patent Number: 8114650

Method for isolating nucleic acids and protein from a single sample
Inventor: Bosnes | Patent Number: 8110351

Matrix metalloproteinase 11 vaccine
Inventor: Aurisicchio, et al. | Patent Number: 8106176

Fluorometric analysis kit
Inventor: Diwu, et al. | Patent Number: 8105829

Method of detecting amplification or deletion in genomic DNA Fragment
Inventor: Amano, et al. | Patent Number: 8105770

Isolation and purification of nucleic acids with a solid phase
Inventor: Birkner, et al. | Patent Number: 8101744

Parallel preparation of high fidelity probes in an array format
Inventor: McGall, et al. | Patent Number: 8101737

Preparation of protective antigen
Inventor: Brehm, et al. | Patent Number: 8101735

Human cytokine receptor
Inventor: Presnell, et al. | Patent Number: 8101381

Process for typing of HCV isolates
Inventor: Maertens, et al. | Patent Number: 8101351

Compositions comprising polidocanol and derivatives
Inventor: Adie, et al. | Patent Number: 8097717

Multitargeting interfering RNAs having two active strands and methods for their design and use
Inventor: Rivory, et al. | Patent Number: 8097715

Ethanol production in bacillus
Inventor: Javed, et al. | Patent Number: 8097460

Recombinant viral-based malaria vaccines
Inventor: Pau, et al. | Patent Number: 8097453

Kits for detecting group B Streptococci
Inventor: Pollner, et al. | Patent Number: 8097409

Non-aggregating fluorescent proteins and methods for using the same
Inventor: Lukyanov, et al. | Patent Number: 8093450

Plasmid purification
Inventor: Van Alstine, et al. | Patent Number: 8093373

Method for deblocking of labeled oligonucleotides
Inventor: Gebeyehu, et al. | Patent Number: 8093372

Method of producing a nucleic acid
Inventor: Maeta, et al. | Patent Number: 8093371

Preparation and isolation of 5' capped mRNA
Inventor: Kore, et al. | Patent Number: 8093367

Biopolymeric arrays having replicate elements
Inventor: Corson | Patent Number: 8093186

Fluorescence energy transfer by competitive hybridization
Inventor: Chiang, et al. | Patent Number: 8093003

Tetrahydropyran nucleic acid analogs
Inventor: Swayze, et al. | Patent Number: 8088904

Chiral selectors for separating enantiomers of a compound
Inventor: Peyrin, et al. | Patent Number: 8088626

Massive parallel method for decoding DNA and RNA
Inventor: Ju, et al. | Patent Number: 8088575

Phosphoramidite nucleoside analogs
Inventor: Bogdanov, et al. | Patent Number: 8084589

Isolated nucleic acid molecules encoding a fusion protein capable of binding VEGF
Inventor: Papadopoulos, et al. | Patent Number: 8084234

Identification of molecular sequence signatures and methods involving the same
Inventor: Lockhart, et al. | Patent Number: 8084197

Oligonucleotide analogues
Inventor: Wengel, et al. | Patent Number: 8080644

Biocatalystic synthesis of quinic acid and conversion to hydroquinone by recombinant microbes
Inventor: Frost, et al. | Patent Number: 8080397

Gene expression control DNA element and associated protein
Inventor: Barber | Patent Number: 8080376

Nucleic acids encoding class II human histone deacetylases, and uses related thereto
Inventor: Grozinger, et al. | Patent Number: 8076116

Device and method for high-throughput quantification of MRNA from whole blood
Inventor: Mitsuhashi | Patent Number: 8076105

Method of detecting the cystic fibrosis transmembrane conductance regulator (CFTR) at cell exterior
Inventor: Riordan | Patent Number: 8076101

Genome-wide chromosome conformation capture
Inventor: Chen, et al. | Patent Number: 8076070

Method for the treatment of a sample containing biomolecules
Inventor: Korfhage, et al. | Patent Number: 8076069

Probe-antiprobe compositions and methods for DNA or RNA detection
Inventor: Shafer | Patent Number: 8076067

Multiplexed methylation detection methods
Inventor: Fan | Patent Number: 8076063

Nucleotide analogs
Inventor: Efcavitch, et al. | Patent Number: 8071755

Polynucleotides encoding rod-derived cone viability factor (rdcvf) and methods of using the same
Inventor: Leveillard, et al. | Patent Number: 8071745

Synthesis of hybrid polynucleotide molecules using single-stranded polynucleotide molecules
Inventor: Harayama, et al. | Patent Number: 8071289

Isolation of DNA, RNA and protein from a single sample
Inventor: Takkellapati, et al. | Patent Number: 8067580

Nucleic acid extraction method
Inventor: Skagestad | Patent Number: 8067579

Substrate preparation process
Inventor: Goldberg, et al. | Patent Number: 8067578

Polymerase chain reaction (PCR) method for amplifying a DNA template
Inventor: Hwang, et al. | Patent Number: 8067174

Device, kit and method for pulsing biological samples with an agent and stabilising the sample so pulsed
Inventor: Stordeur, et al. | Patent Number: 8067172

Method for isolating both free and protein association DNA
Inventor: Haj-Ahmad | Patent Number: 8063199

Processes and reagents for desilylation of oligonucleotides
Inventor: Manoharan, et al. | Patent Number: 8063198

Method for making a polymer blend for reducing protein binding to surfaces
Inventor: Bookbinder, et al. | Patent Number: 8062881

Use of acetals for isolation of nucleic acids
Inventor: Donner, et al. | Patent Number: 8062843

Processes and reagents for sulfurization of oligonucleotides
Inventor: Manoharan, et al. | Patent Number: 8058448

Aptamer- and nucleic acid enzyme-based systems for simultaneous detection of multiple analytes
Inventor: Lu, et al. | Patent Number: 8058415

Foot and mouth disease virus vaccine comprising interferons
Inventor: Grubman, et al. | Patent Number: 8058248

Labeled nucleotide analogs and uses therefor
Inventor: Xu, et al. | Patent Number: 8058031

Oligonucleotide mediated nucleic acid recombination
Inventor: Crameri, et al. | Patent Number: 8058001

Species-specific primer sets and identification of species-specific DNA sequences using genome fragment enrichment
Inventor: Shanks, et al. | Patent Number: 8058000

Nucleic acid binding compounds containing pyrazolo[3,4-D]pyrimidine analogues of purin-2,6-diamine and their uses
Inventor: Seela, et al. | Patent Number: 8057997

Detection of PCR products in gel electrophoresis
Inventor: Birkner | Patent Number: 8053213

Linkers and co-coupling agents for optimization of oligonucleotide synthesis and purification on solid supports
Inventor: Gao, et al. | Patent Number: 8053187

Methods for nucleic acid isolation and instruments for nucleic acid isolation
Inventor: Yamashita, et al. | Patent Number: 8048681

Methods and compositions for cellular and metabolic engineering
Inventor: Minshull, et al. | Patent Number: 8048674

Polynucleotides encoding modified DNA cleavage enzymes and host cells therefor
Inventor: Guan, et al. | Patent Number: 8048664

Methods for detecting and monitoring cancer using extracellular RNA
Inventor: Kopreski | Patent Number: 8043835

Purification method and kits
Inventor: Danks, et al. | Patent Number: 8043811

Method of treating inflammatory lung disease with suppressors of CpG oligonucleotides
Inventor: Klinman, et al. | Patent Number: 8043622

Methods of purifying a nucleic acid and formulation and kit for use in performing such methods
Inventor: Bitner | Patent Number: 8039613

Synthesis of oligonucleotides or phosphorothioate oligonucleotide with a capping agent of N-methylimidazole free of 1,3,5-trimethylhexahydro-1,3,5-triazine
Inventor: Lorenz, et al. | Patent Number: 8039612

2'-hydroxyl group-modified ribonucleoside derivatives
Inventor: Sekine, et al. | Patent Number: 8039611

Process for production of crystal of purine nucleoside compound
Inventor: Naito, et al. | Patent Number: 8034924

Parallel preparation of high fidelity probes in an array format
Inventor: McGall, et al. | Patent Number: 8034912

Nucleic acid anchoring system comprising covalent linkage of an oligonucleotide to a solid support
Inventor: Poetter, et al. | Patent Number: 8034911

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