Patent International Class: A61P 29/0

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Tricyclic N-heteroaryl-carboxamide derivatives, preparation and therapeutic use thereof
Inventor: Dubois, et al. | Patent Number: 8153796

Bicyclic and tricyclic derivatives as thrombin receptor antagonists
Inventor: Chackalamannil, et al. | Patent Number: 8153664

Heterocyclic derivatives as modulators of ion channels
Inventor: Hilgraf, et al. | Patent Number: 8143297

Heterocyclic compounds
Inventor: Chen, et al. | Patent Number: 8143282

Methods of treatment using WISP polypeptides
Inventor: Desnoyers, et al. | Patent Number: 8138152

HMG1 antibody for treating inflammatory conditions
Inventor: Tracey, et al. | Patent Number: 8138141

Non steroidal glucocorticoid receptor modulators
Inventor: Plate, et al. | Patent Number: 8133885

Carbonyl compounds
Inventor: Tsaklakidis, et al. | Patent Number: 8129373

(2S,3R)-N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)benzofuran-- 2-carboxamide, novel salt forms, and methods of use thereof
Inventor: Dull, et al. | Patent Number: 8119659

Inhibitors of interleukin-1.beta. converting enzyme
Inventor: Batchelor, et al. | Patent Number: 8119631

1,4-disubstituted naphthalenes as inhibitors of p38 map kinase
Inventor: Ashwell, et al. | Patent Number: 8114873

Immune stimulatory infant nutrition
Inventor: Boehm, et al. | Patent Number: 8114441

Compositions and methods for modulating c-kit and PDGFR receptors
Inventor: Liu, et al. | Patent Number: 8106068

Cyclopentathiophene modulators of the glucocorticoid receptor, AP-1, and/or NF-.kappa.B activity and use thereof
Inventor: Yang | Patent Number: 8106046

Chimeric toll-like receptor/MD-2 polypeptides and methods of use thereof
Inventor: Elson | Patent Number: 8106018

N-acylhydrazone derivatives useful as modulators of nicotinic acetylcholine receptors
Inventor: Nardi, et al. | Patent Number: 8101649

Phthalazine compounds and methods of use
Inventor: Tasker, et al. | Patent Number: 8101612

Diazaquinolones that inhibit prolyl hydroxylase activity
Inventor: Allen, et al. | Patent Number: 8097620

Process for preparation of high-purity meloxicam and meloxicam potassium salt
Inventor: Mezei, et al. | Patent Number: 8097616

Dialkylamino alkyl esters of pivagabine as medicaments for the treatment of central nervous system disorders
Inventor: Rafferty | Patent Number: 8080548

Carbocyclic GlyT-1 receptor antagonists
Inventor: Kolczewski, et al. | Patent Number: 8080541

2-cyanophenyl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine compounds, compositions and uses thereof
Inventor: Wei, et al. | Patent Number: 8076345

Triazolopyridazines as PAR1 inhibitors, production thereof, and use as medicaments
Inventor: Heinelt, et al. | Patent Number: 8076336

Purine derivatives as a2a agonists
Inventor: Fairhurst, et al. | Patent Number: 8071565

Peptides and peptide derivatives, the production thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition
Inventor: Petzelbauer, et al. | Patent Number: 8067533

Compounds and compositions for treating infection
Inventor: Chepkwony, et al. | Patent Number: 8067401

Human TNF receptor fusion protein
Inventor: Brockhaus, et al. | Patent Number: 8063182

Pyridazine compounds and methods
Inventor: Watterson, et al. | Patent Number: 8063047

Pyridine methylene azolidinones and use thereof phosphoinositide inhibitors
Inventor: Rueckle, et al. | Patent Number: 8058289

7H-pyrido[3,4-D]pyrimidin-8-ones, their manufacture and use as protein kinase inhibitors
Inventor: Honold, et al. | Patent Number: 8058283

Thienotriazolodiazepine compound and medicinal use thereof
Inventor: Adachi, et al. | Patent Number: 8044042

Cycloalkane[B]azaindole antagonists of prostaglandin D.sub.2 receptors
Inventor: Hutchinson, et al. | Patent Number: 8034826

CCR9 inhibitors and methods of use thereof
Inventor: Fleming, et al. | Patent Number: 8030517

Modified lysine-mimetic compounds
Inventor: Larsen, et al. | Patent Number: 8026272

Fused pyridone M1 receptor positive allosteric modulators
Inventor: Beshore, et al. | Patent Number: 8022215

Modified release compositions of milnacipran
Inventor: Hirsh, et al. | Patent Number: 8021687

Use of acetyl L-carnitine for the treatment of fibromyalgic syndrome
Inventor: Koverech | Patent Number: 8013016

Pyrimidyl cyclopentanes as AKT protein kinase inhibitors
Inventor: Mitchell, et al. | Patent Number: 8003651

CCR9 inhibitors and methods of use thereof
Inventor: Fleming, et al. | Patent Number: 7999109

Pyrimidodiazepinone derivative
Inventor: Otsubo, et al. | Patent Number: 7998954

Methods for treating an inflammatory disease of the bowel
Inventor: Kelly | Patent Number: 7998474

(2S,3R)-N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl-benzofuran-- 2-carboxamide, novel salt forms, and methods of use thereof
Inventor: Dull, et al. | Patent Number: 7981906

CCR1 antagonists and methods of use therefor
Inventor: Carson, et al. | Patent Number: 7977350

Sulfonyl amino cyclic derivatives and use thereof
Inventor: Swinnen, et al. | Patent Number: 7973039

Pyridazinone kinase inhibitors
Inventor: Hoelder, et al. | Patent Number: 7968546

Substituted bicyclocarboxyamide compounds
Inventor: Ando, et al. | Patent Number: 7964732

Method for treating a mammal by administration of a compound having the ability to release CO
Inventor: Haas, et al. | Patent Number: 7964220

Crystal forms of an imidazole derivative
Inventor: Haruta, et al. | Patent Number: 7960407

Pyridazin-3(2H)-one derivatives and their use as PDE4 inhibitors
Inventor: Buil Albero, et al. | Patent Number: 7960383

Substituted pyrrolo[2,3-d]pyrimidines as antifolates
Inventor: Roberts, et al. | Patent Number: 7951812

Pyrrolo[2,3-D]pyrimidine derivatives substituted with a cyclic amino group
Inventor: Nakazato, et al. | Patent Number: 7951811

Substituted pyrrolo[2,3-d]pyrimidines as inhibitors of E1 activating enzymes
Inventor: Critchley, et al. | Patent Number: 7951810

Process for preparing a pharmaceutical composition with anti-inflammatory and analgesic activity for administration via a patch for external use, and composition thus obtained
Inventor: Troiano, et al. | Patent Number: 7943668

Pyridinylpyrazolopyrimidinone derivatives as PDE 7 inhibitors
Inventor: Inoue, et al. | Patent Number: 7943624

Azaindoles for inhibiting aurora2 and other kinases
Inventor: Cox, et al. | Patent Number: 7943616

Compounds which modulate the CB2 receptor
Inventor: Berry, et al. | Patent Number: 7935715

Pyrrolo[2,3-d]pyrimidine derivatives substituted with a cyclic amino group
Inventor: Nakazato, et al. | Patent Number: 7932259

Substituted pyrazolo[4,3-d]pyrimidines as aurora kinase inhibitors
Inventor: Oslob, et al. | Patent Number: 7932257

Substituted pyrazolo[3,4-d]pyrimidines as PI3K inhibitors
Inventor: Chen, et al. | Patent Number: 7919498

Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
Inventor: Palle, et al. | Patent Number: 7915286

Therapeutic compounds
Inventor: Savory | Patent Number: 7906518

Di-fluoro containing compounds as cysteine protease inhibitors
Inventor: Link, et al. | Patent Number: 7893112

Aza-benzothiophenyl compounds and methods of use
Inventor: Savy, et al. | Patent Number: 7893085

Physiologically active substances
Inventor: Kotake, et al. | Patent Number: 7893068

Heterocyclic inhibitors of MEK and methods of use thereof
Inventor: Marlow, et al. | Patent Number: 7893065

7-membered ring compound and method of production and pharmaceutical application thereof
Inventor: Muto, et al. | Patent Number: 7888348

Hyaluronic acid derivative and drug containing the same
Inventor: Miyamoto, et al. | Patent Number: 7879817

Phthalazinones
Inventor: Buchstaller, et al. | Patent Number: 7875614

Fused bicycloheterocycle substituted azabicyclic alkane derivatives
Inventor: Ji, et al. | Patent Number: 7872017

Pyrazinyl substituted piperazine-piperidines with CXCR3 antagonist activity
Inventor: Rosenblum, et al. | Patent Number: 7868005

Compounds and methods for kinase modulation, and indications therefor
Inventor: Spevak, et al. | Patent Number: 7863289

Isethionate salt of a selective CDK4 inhibitor
Inventor: Beylin, et al. | Patent Number: 7863278

Aza-indolyl compounds and methods of use
Inventor: Goodacre, et al. | Patent Number: 7855216

Fused cyclic systems useful as inhibitors of TEC family protein kinases
Inventor: Jimenez, et al. | Patent Number: 7855214

N,N'-diphenylurea derivatives suitable as kinase inhibitors
Inventor: Hoelzemann, et al. | Patent Number: 7846927

Pyridine methylene azolidinones and use thereof phosphoinositide inhibitors
Inventor: Rueckle, et al. | Patent Number: 7842698

Pyrrolo [3,2-d]pyrimidin-4-one derivatives and their use in therapy
Inventor: Bogevig, et al. | Patent Number: 7829707

1,4-disubstituted naphthalenes as inhibitors of P38 MAP kinase
Inventor: Ashwell, et al. | Patent Number: 7829560

CCR9 inhibitors and methods of use thereof
Inventor: Fleming, et al. | Patent Number: 7820717

2-(piperidin-4-yl)-4,5-dihydro-2H-pyridazin-3-one derivatives as PDE4 inhibitors
Inventor: Menge, et al. | Patent Number: 7820669

Phthalazine derivatives as parp inhibitors
Inventor: Mevellec, et al. | Patent Number: 7803795

Method for producing albumin conjugates containing gyrase inhibitors
Inventor: Sinn, et al. | Patent Number: 7803791

Aryl nitrile compounds and compositions and their uses in treating inflammatory and related disorders
Inventor: Bergeron, et al. | Patent Number: 7799795

5-lipoxygenase-activating protein (FLAP) inhibitors
Inventor: Hutchinson, et al. | Patent Number: 7795274

Substituted pyrimidinones
Inventor: Durley | Patent Number: 7795271

Substituted arylpyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
Inventor: Hartung, et al. | Patent Number: 7795264

Thiazole derivatives as phosphodiesterase IV inhibitors
Inventor: Eggenweiler, et al. | Patent Number: 7790723

Inhibitors of interleukin-1.beta. converting enzyme
Inventor: Batchelor, et al. | Patent Number: 7790713

Phenylalanine enamide derivatives
Inventor: Brand, et al. | Patent Number: 7786177

Fluridone as an anti-inflammatory agent
Inventor: Zocchi, et al. | Patent Number: 7786042

Enhancement of activity and/or duration of action of selected anti-inflammatory steroids for topical or other local application
Inventor: Bodor | Patent Number: 7776846

Arylamino N-heteroaryl compounds as MEK inhibitors
Inventor: Goutopoulos, et al. | Patent Number: 7772233

Quinazolinyl compounds as inhibitors of potassium channel function
Inventor: Johnson, et al. | Patent Number: 7772232

Aminopyrimidines useful as kinase inhibitors
Inventor: Binch, et al. | Patent Number: 7767672

Substituted 3-carboxamido isoxazoles as kinase modulators
Inventor: Mehta, et al. | Patent Number: 7767670

Pyrimidinyl amide compounds which inhibit leukocyte adhesion mediated by VLA-4
Inventor: Semko, et al. | Patent Number: 7763632

Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia
Inventor: Palani, et al. | Patent Number: 7763623

Pyrazolopyridine-4-yl pyridazinone derivatives and addition salts thereof, and PDE inhibitors comprising the same derivatives or salts as active ingredient
Inventor: Kohno, et al. | Patent Number: 7763617

Piperazine-piperidines with CXCR3 antagonist activity
Inventor: Yu, et al. | Patent Number: 7763616

Phthalazine compounds and methods of use
Inventor: Tasker, et al. | Patent Number: 7759337

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