Patent International Class: A61K 38/46
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Activatable photodynamic therapy agents
Inventor: Zheng, et al. | Patent Number: 8133482
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Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
Inventor: Vellard, et al. | Patent Number: 8128925
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EGLN2 variants and use thereof in preventing or treating thromboembolic disorders and coronary heart disease
Inventor: Kozian, et al. | Patent Number: 8114398
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Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
Inventor: Bookbinder, et al. | Patent Number: 8105586
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Method for the treatment of the symptoms of drug and alcohol addiction
Inventor: Fallon | Patent Number: 8084025
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Transdiscal administration of cycline compounds
Inventor: Attawia, et al. | Patent Number: 8067397
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Enzyme inhibitors of PAI-1
Inventor: Jolly | Patent Number: 8066991
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Lysin protein having broad antibacterial activity specific to bacteria
Inventor: Yoon, et al. | Patent Number: 8066990
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Lysosomal phospholipase A2 (LPLA2) activity as a diagnostic and therapeutic target for identifying and treating systemic lupus erythematosis
Inventor: Shayman, et al. | Patent Number: 8052970
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Enzyme with microbial lysis activity from Trichoderma reesei
Inventor: Van Kimmenade, et al. | Patent Number: 8048412
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Recombinant human T2 RNase and uses thereof
Inventor: Roiz, et al. | Patent Number: 8039240
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Compositions and methods for the prevention and removal of biofilms on inert and biological surfaces
Inventor: Wang, et al. | Patent Number: 8038990
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Anti-ageing skin cosmetic
Inventor: Golz-Berner, et al. | Patent Number: 8034385
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Modified beta-lactamase and method for its preparation
Inventor: Kaariainen, et al. | Patent Number: 7989192
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Ophthalmic surgical irrigating solutions containing hyaluronidase and method for preventing post-operative intraocular pressure increases
Inventor: Soll | Patent Number: 7976833
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Delivery of therapeutic agents to the bone
Inventor: Tomatsu, et al. | Patent Number: 7972593
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Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation
Inventor: Cheng, et al. | Patent Number: 7951366
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Removing dental plaque with krill enzymes
Inventor: Franklin | Patent Number: 7947270
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Defense and counter-defense compositions and methods
Inventor: Koizumi | Patent Number: 7943127
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Method of therapy for degenerative intervertebral discs
Inventor: Haro | Patent Number: 7935337
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Hafnia phytase
Inventor: Lassen, et al. | Patent Number: 7923232
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High-activity mutants of butyrylcholinesterase for cocaine hydrolysis and method of generating the same
Inventor: Zhan, et al. | Patent Number: 7919082
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Composition exhibiting a von willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
Inventor: Laemmle, et al. | Patent Number: 7910094
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High activity mutants of butyrylcholinesterase for cocaine hydrolysis
Inventor: Zhan, et al. | Patent Number: 7892537
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Supplements for pain management
Inventor: Ziff, et al. | Patent Number: 7871609
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Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
Inventor: Bookbinder, et al. | Patent Number: 7871607
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Polypeptides having phytase activity and polynucleotides encoding same
Inventor: Wik, et al. | Patent Number: 7867743
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Phytases and methods of making and using them
Inventor: Short | Patent Number: 7863031
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Alkaline phosphatase to control diabetes
Inventor: Kiss | Patent Number: 7858085
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Galenic formulation for colon-targeted delivery of active ingredients
Inventor: Bourgeois, et al. | Patent Number: 7833765
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Treatment of .alpha.-galactosidase A deficiency
Inventor: Treco, et al. | Patent Number: 7833742
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Compositions and methods for enzymatic detachment of bacterial and fungal biofilms
Inventor: Kaplan | Patent Number: 7833523
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Reduction of adipose tissue
Inventor: Wegman, et al. | Patent Number: 7824673
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Compositions and methods for treating collagen-mediated diseases
Inventor: Sabatino, et al. | Patent Number: 7811560
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Ointment wound spray
Inventor: Jones, et al. | Patent Number: 7785584
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Polypeptides having lipase activity and polynucleotides encoding same
Inventor: Niu, et al. | Patent Number: 7781200
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Large-scale production of human serum butyrylcholinesterase as a bioscavenger
Inventor: Doctor, et al. | Patent Number: 7754461
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High activity mutants of butyrylcholinesterase for cocaine hydrolysis
Inventor: Zhan, et al. | Patent Number: 7740840
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Method for screening of a lipase having improved enzymatic activity using yeast surface display vector and the lipase
Inventor: Choi, et al. | Patent Number: 7736643
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Use of bromelain for the treatment of inflammatory diseases and for adjuvant therapy during wound healing processes
Inventor: Maurer, et al. | Patent Number: 7731958
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High-activity mutants of butyrylcholinesterase for cocaine hydrolysis and method of generating the same
Inventor: Zhan, et al. | Patent Number: 7731957
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Compositions and methods of using chondroitinase ABCI mutants
Inventor: Caggiano, et al. | Patent Number: 7731956
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Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
Inventor: Vellard, et al. | Patent Number: 7722865
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Compositions and methods of using chondroitinase ABCI mutants
Inventor: Caggiano, et al. | Patent Number: 7722864
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System and device for prevention and neutralization of bioactive substances and generating an aroma-producing substance
Inventor: Hyacinthe | Patent Number: 7722838
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Alkaline phosphatase compositions to reduce skin cancer
Inventor: Kiss | Patent Number: 7718170
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Use of alkaline phosphatase to maintain healthy tissue mass in mammals
Inventor: Kiss | Patent Number: 7695714
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Dynamin mediated diseases and associated methods and products
Inventor: Reiser, et al. | Patent Number: 7670817
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Pharmaceutical composition for treatment of phimosis using topical corticosteroid
Inventor: Palma | Patent Number: 7666858
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Insect inhibitory lipid acyl hydrolases
Inventor: Alibhai, et al. | Patent Number: 7662372
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Stable digestive enzyme compositions
Inventor: Ortenzi, et al. | Patent Number: 7658918
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Methods of enhancing lysosomal storage disease therapy by modulation of cell surface receptor density
Inventor: Zhu, et al. | Patent Number: 7658916
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Treatment of Pompe's disease
Inventor: Van Bree, et al. | Patent Number: 7655226
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Class of therapeutic protein based molecules
Inventor: Fang, et al. | Patent Number: 7645448
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Wound treatment utilizing collagenase and a phosphotidylcholine organogel
Inventor: Soroff, et al. | Patent Number: 7641900
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Fungal cell wall degrading enzyme
Inventor: Wu, et al. | Patent Number: 7635470
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Plant gene and uses thereof
Inventor: Gidekel, et al. | Patent Number: 7622109
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Preparation of phytase-containing granulates for use in animal feed
Inventor: Barendse, et al. | Patent Number: 7611701
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Vascular endothelial growth factor fusion constructs used to inhibit osteoclastogenesis
Inventor: Rosenblum | Patent Number: 7601341
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Enzyme disruption of bacterial biofilms
Inventor: Kokai-Kun, et al. | Patent Number: 7572439
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Phage-associated lytic enzymes for treatment of Streptococcus pneumoniae and related conditions
Inventor: Fischetti, et al. | Patent Number: 7569223
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Biological glue based on thrombin-conjugated nanoparticles
Inventor: Margel, et al. | Patent Number: 7550282
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Alpha-amylase variants with altered properties
Inventor: Power, et al. | Patent Number: 7541026
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Degradation of hydrophobic ester pesticides and toxins
Inventor: Russell, et al. | Patent Number: 7524494
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Composition exhibiting a von Willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
Inventor: Laemmle, et al. | Patent Number: 7501117
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Placental alkaline phosphatase to control diabetes
Inventor: Kiss | Patent Number: 7501116
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Lipid phosphate phosphatases and uses thereof for treating neuronal diseases
Inventor: Nitsch, et al. | Patent Number: 7494645
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Compositions and methods of using chondroitinase ABCI mutants
Inventor: Caggiano, et al. | Patent Number: 7485295
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Galenic pectinate formulation for colon-targeted delivery of antibiotic-inactivating enzymes and method of use thereof
Inventor: Bourgeois, et al. | Patent Number: 7485294
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Recombinant bacterial phytases and uses thereof
Inventor: Short, et al. | Patent Number: 7452706
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High-activity mutants of butyrylcholinesterase for cocaine hydrolysis and method of generating the same
Inventor: Zhan, et al. | Patent Number: 7438904
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Phytases and methods for making and using them
Inventor: Short, et al. | Patent Number: 7432098
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Phytases, nucleic acids encoding them and methods of making and using them
Inventor: Short, et al. | Patent Number: 7432097
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Therapeutic composition containing a plurality of immobilized proteases
Inventor: Artamonov, et al. | Patent Number: 7429377
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Biologically active conjugate of a biopolymer and therapeutic agent
Inventor: Calias, et al. | Patent Number: 7417021
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Human DNase I hyperactive variants
Inventor: Lazarus, et al. | Patent Number: 7407785
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Composition and method for treating non-bacterial cystitis
Inventor: Katske, et al. | Patent Number: 7402311
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Deoxyribonuclease, gene encoding same and use thereof
Inventor: Tanuma, et al. | Patent Number: 7402310
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Phage-associated lytic enzymes for treatment of Bacillus anthracis and related conditions
Inventor: Fischetti, et al. | Patent Number: 7402309
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Biological pesticide
Inventor: Tvedten | Patent Number: 7393528
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Protein
Inventor: Zimmer, et al. | Patent Number: 7371375
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Stabilized bioactive peptides and methods of identification, synthesis, and use
Inventor: Altman | Patent Number: 7365162
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Bioactive peptides, uses thereof and process for the production of same
Inventor: Raa, et al. | Patent Number: 7358332
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Peptides and compositions which modulate apoptosis
Inventor: Chittenden, et al. | Patent Number: 7358088
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Treatment of Pompe's disease
Inventor: van Bree, et al. | Patent Number: 7351410
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Method of treatment with modified arginine deiminase
Inventor: Clark | Patent Number: 7323167
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Enzyme treatment of foodstuffs for Celiac Sprue
Inventor: Shan, et al. | Patent Number: 7320788
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Pharmaceutical compositions of fibrinolytic agent
Inventor: Kendrick, et al. | Patent Number: 7311908
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Compositions and methods for enzymatic detachment of bacterial and fungal biofilms
Inventor: Kaplan | Patent Number: 7294497
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Health enhancement method
Inventor: Schakel, legal representative, et al. | Patent Number: 7273607
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2-O sulfatase compositions and related methods
Inventor: Sasisekharan, et al. | Patent Number: 7270815
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Method and composition for inhibiting cancer cell growth
Inventor: Segal, et al. | Patent Number: 7264800
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Local anesthetic methods and kits
Inventor: Weber, et al. | Patent Number: 7261889
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Combined use of triglycerides containing medium chain fatty acids and exogenous lipolytic enzymes as feed supplements
Inventor: Decuypere, et al. | Patent Number: 7261888
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Proteases from Carica having mitogenic activity and their methods of use
Inventor: Salas, et al. | Patent Number: 7258856
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Polypeptides having phospholipase A.sub.2 activity
Inventor: Miyaji, et al. | Patent Number: 7258855
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Methods for sterilizing preparations containing albumin
Inventor: Miekka, et al. | Patent Number: 7252799
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Therapeutic use of soluble CD39L3
Inventor: Chen, et al. | Patent Number: 7247300
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Pharmaceutical compositions of fibrinolytic agent
Inventor: Kendrick, et al. | Patent Number: 7244426
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Method for producing proteins suitable for treating lysosomal storage disorders
Inventor: D'Azzo, et al. | Patent Number: 7241442