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					Authors:       S. Canny and M. Southern
Title:         PubChem Assay Upload Excel Template.
Version:       20110922
Description:   This is an Excel template for uploading PubChem assays into the PubChem Deposition
               System. This template provides drop down lists for fields where there are particular
               allowed values so that you don't need to remember or refer to the vocabulary. Look also
               for Excel's Cell Comments (red triangles) for more information.
Contact:       southern@scripps.edu
References:    http://pubchem.ncbi.nlm.nih.gov/deposit/deposit_help.html#assay_descr.load
. Look also
DESCR_TAG                         DESCR_VALUE
PUBCHEM_EXT_DATASOURCE_REGID      Unique assay identifier, e.g. 'Assay 1'
PUBCHEM_ASSAY_NAME                Name of the assay, e.g. 'Allosteric Modulators of D1 Receptors'
PUBCHEM_GRANT_NUMBER              123456
PUBCHEM_PROJECT_CATEGORY          NIH_MLPCN
PUBCHEM_ACTIVITY_OUTCOME_METHOD   CONFIRMATORY
PUBCHEM_SUBSTANCE_TYPE            SMALL_MOLECULE
PUBCHEM_HOLD_UNTIL_DATE           2011/12/31
                                  PubChem bioassay description can be entered either here or via
PUBCHEM_ASSAY_DESCRIPTION         categorized comments CSV file
PUBCHEM_ASSAY_DESCRIPTION
PUBCHEM_ASSAY_DESCRIPTION         Multiple rows can be used for the description.
                                  PubChem bioassay protocol can be entered either here or via
PUBCHEM_ASSAY_PROTOCOL            categorized comments CSV file
PUBCHEM_ASSAY_PROTOCOL
PUBCHEM_ASSAY_PROTOCOL            Multiple rows can be used for the protocol.
                                  PubChem bioassay comments can be entered either here or via
PUBCHEM_ASSAY_COMMENTS            categorized comments CSV file
PUBCHEM_ASSAY_COMMENTS
PUBCHEM_ASSAY_COMMENTS            Multiple rows can be used for the comments.
TARGET_TYPE               TARGET_ID   TARGET_DESCRIPTION   TARGET_COMMENT
PUBCHEM_NCBI_PROTEIN_GI        299681
TARGET_NAME
D(1A) dopamine receptor [Homo sapiens]
XREF_TYPE                    XREF_VALUE
PUBCHEM_NCBI_TAXONOMY_ID     9606
PUBCHEM_AID                  641
PUBCHEM_AID                  858
PUBCHEM_EXT_DATASOURCE_URL   http://www.yoursite.com
PUBCHEM_NCBI_GENE_ID         1812

PUBCHEM_NCBI_PUBMED_ID       15974933
XREF_ANNOTATION
human sequences
Screening assay
Confirmatory assay
My home page
DRD1 dopamine receptor D1 [ Homo sapiens ]

Allosteric modulation of dopamine receptors, Schetz JA., Mini Rev Med Chem. 2005 Jun; 5(6):555-61
XREF_TYPE_QUALIFIER




PRIMARY_CITATION
CAT_COMMENT_TAG                        CAT_COMMENT_VALUE
Instrument name                         Instrument Z (2.2.6.1)   If there are no Categorized Comments, then thi
Instrument manufacturer                 Company Y(2.2.6.2)       sheet will need to be deleted before upload to
Assay plate manufactuer                 Company X (2.2.10)       PubChem.
Assay plate type                       Type X (2.2.11)
Delivery reagent type                  inhibitor(2.2.8.1)
Delivery reagent manufacturer          Sigma-Aldrich (2.2.8.6)
Delivery reagent name                  compound_123 (2.2.8.3)
Delivery reagent final concentration   23 micromolar (2.2.8.4)
    Comments, then this
leted before upload to
RESULT_ID       RESULT_NAME               RESULT_TYPE   RESULT_DESCR
            1   Hit Confirmation          FLOAT         Confirmed by individial siRNA in Bmac1_dLuc
            2   Phenotype                 STRING        Biological effect type
            3   replicate1_readout_0_hr   FLOAT         bioluminescence measurement
            4   replicate1_readout_2_hr   FLOAT         bioluminescence measurement
            5   replicate1_readout_4_hr   FLOAT         bioluminescence measurement
RESULT_UNIT   RESULT_ATTR_CONC_MICROMOL   RESULT_CONC_RESPONSE_SERIES_ID
MICROMOLAR
NONE
PERCENT
PERCENT
PERCENT
RESULT_IS_ACTIVE_CONCENTRATION
                 TRUE

				
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posted:10/18/2011
language:English
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