Dopamine Hydrochloride Drug Study

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					    NAME OF DRUG                 CLASSIFICATION          MECHANISM OF ACTION                      INDICATION             CONTRAINDICATION                   ADVERSE EFFECTS                            NURSING RESPONSIBILITIES

GENERIC NAME:                    Autonomic Nervous     Stimulates dopaminergic and alpha     • To treat shock &          • Contraindicated in            CNS:                            BEFORE:
dopamine hydrochloride             System Agent        and beta receptors of the               correct hemodynamic         patients with uncorrected     headache                         1) Determine hypersensitivity to drug or its components.
                                   (Alpha & Beta       sympathetic nervous system.             imbalances, to improve      tachyarrhythmias,             CV:                              2) Drug isn’t a substitute for blood or fluid volume deficit. If
TRADE NAME:                      Adrenergic Agonist)   Action is dose-related; large doses     perfusion to vital          pheochromocytoma, or          ectopic beats, tachycardia,         deficit exists, replace fluid before giving vasopressors.
Doastat, Intropin, Revimine                            cause mainly alpha stimulation.         organs, to increase         ventricular fibrillation      angina, palpitations,            3) Screen for presence of vascular disease in patients.
                                                                                               cardiac output, to        • Use cautiously in patients    hypotension                      4) Monitor patient’s urine output & skin color.
MAXIMUM DOSE:                                                                                  correct hypotension         with occlusive vascular       GI:                              5) Don’t confuse dopamine with dobutamine.
10 mcg / kg / min IV                                                                         • To correct                  disease, cold injuries,       nausea, vomiting
                                                                                               hemodynamic                 diabetic endarteritis, &      METABOLIC:                      DURING:
MINIMUM DOSE:                                                                                  imbalance in shock          arterial embolism; in         azotemia, hyperglycemia          1) Use extreme caution in calculating doses of drugs.
2 mcg / kg / min IV                                                                            syndrome due to MI          pregnant patients; in those   RESPIRATORY:                     2) During infusion, frequently monitor ECG, BP, cardiac
                                                                                               (cardiogenic shock),        with a history of sulfite     dyspnea, asthmatic episodes         output, CVP, pulmonary artery wedge pressure.
AVAILABILITY:                                                                                  open heart surgey, &        sensitivity; and in those     SKIN:                            3) Monitor urine output and color often.
Injections:                                                                                    CHF                         taking MAOI                   necrosis and tissue sloughing    4) If diastolic pressure rises disproportionately in a patient
40mg/mL, 80mg/mL,                                                                                                                                        with extravasation,                 receiving dopamine, decrease infusion rate and watch
160mg/mL parenteral                                                                                                                                      piloerection                        carefully for further evidence of predominant vasoconstrictor
concentrate for injection for                                                                                                                            OTHER:                              activity.
IV infusion; 0.8mg/mL (200                                                                                                                               anaphylactic reaction            5) Observe patient closely for adverse reactions, dosage may
or 400mg) in D5W;                                                                                                                                                                            need to be adjusted or stopped.
1.6mg/mL (400 or 800mg)
in D5W; 3.2mg/mL (800mg)                                                                                                                                                                 AFTER:
in D5W parenteral injection                                                                                                                                                               1) After drug is stopped, watch closely for sudden drop in BP.
for IV infusion                                                                                                                                                                              Taper dosage slowly to evaluate stability of BP.
                                                                                                                                                                                          2) Acidosis decreases effectiveness of dopamine. Monitor it.
CONTENT:                                                                                                                                                                                  3) Tell patient to report adverse reactions promptly.
dopamine hydrochloride                                                                                                                                                                    4) Instruct patient to report discomfort at IV insertion site.
                                                                                                                                                                                          5) Advise patient to inform nurse immediately if chest pain,
PATIENT’S DOSE:                                                                                                                                                                              dyspnea, burning sensation of extremities occurs.
No specific patient




SOURCE:                         SOURCE:                SOURCE:                               SOURCE:                    SOURCE:                          SOURCE:                         SOURCE:
NDH 2005 p. 580                 NDG 2004 p.526         NDH 2005 p. 580                       NDH 2005 p. 580            NDH 2005 p. 580                  NDH 2005 p. 580                 NDH 2005 p. 580
NDG 2004 p.526                                                                               NDG 2004 p.526                                              NDG 2004 p.527                  Davis Drug Guide p. 341




                                                                                                                                                                                                                                HERBERT ALMENDRAS HUYO
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Description: Dopamine Hydrochloride Drug Study