!l THE WELLCOME TRUST l
Fourth Report I
covering the period
52 QUEEN ANNE STREET,.
TUBW e ~ r c o M a T ~ u m = ,
1963 . . . . S
THE WELLCOMB Tnum FOUR~H REPORT(cweriog the
I. h t d u c t i o n
Notable Evenu h
; ,~ e 19&41'
U. Research m Hurmn and Animal Medidne
k : :
htematio&l scope of the ~ A t ' kctivjtik
Classificationof Research Gran-.
(iv) ;*II&~~, i;rho~or;ht~s i
(V) : :fididQs ; :
7 a e b: *
(vi) Grants& h r c h Eqxmn ood Aoistanrr
(vii) T r a d Groats . . . .
(viii) Grants to aid ofS,mpda, and Blo* Trmd
Gronu . . . . . .
( x Grants In old .fPubllrorlon . .
Ill. Medical Research Museums and Liblariw
Reearch i the History OE Medicine
Made a d hinted in Great Brit& by
William Clowen md Sow, Limited, London md Beecles
T H E WELLCOME TRUSTEES, 1963
THE RT. HON. LORD PIERCY,C.B.E. (Choirmon)
BRIGADIER SIR JOHN SMITH KNOX BOYD.
O.B.E., M D , D.P.H., P.R.C.P., P.R.S.
' n o ~ r s s o n JOHN MCMICHAEL, .D., P.R.c.P., P.R.S.
ROBEETMAUU~ON E S' ~
SIR HENRY H. DALE,
O.M., G.B.P., M.D., P.R.C.P., P.R.S.
! J. E. K. P.C.A.
F. H. K. GREEN, C.B.E.. M D , P.R.C.P.
D e p q Scimtii Sewetay
T HE period dealt with in this Report has seen the retiremmt
from his Trusteeship of Mr. Lancelot Claude Bullock and bis
replacement by Mr. Robert Malleson Nesbitt.
Mr. Bullock, who retired on the 5th September 1961, was
one of the origbl five Trustees appointed by Sir H a y
Wellcarne'r Will. As a member of the h of Markby,
Stewart and Wadesons, who were Sir Henry Wellmme's 1 1
advisers, he h d been persma11y concerned in the
1 Will by which the Trust was created, and of the urplanatoty
1 Memoandurn which was to accompmy it. 'Ihb clare funilis-
greatly miss his devoted interert and eRective advice in their THE WELLCOME TRUST
adminiskative duties, and the personal &m of his com-
panionship. ?hey have been glad to welcome as his successor FOURTH REPORT
in the Trusteeship, Mr. Nesbitr, who had kllowed him as covering the period 1960-62
senior partner in the same firm of Solicitors.
The Trustees were very sorry to learn of the protracted I. Introduction
T HE first three Reports, issued in zp57, 1959 aud 1961
tary fmm November 1956 until July 1958, and had more respectively, have recorded the history of the Well-e
recently served as a part-time adviser and as a member of the Tmst to the jlst August 1960, and have dewibed ib
Travel Grants Committee. They are e l d to know that he is
relation to the Wellcome Foundation Limited, the world-
Dr. P. 0.Williams, who had served the Trust as Assistant wide pharmaceutical business of wbich the dividends pm-
Scientific Secremy since February 1960, has been appointed vide the Tmst's annual income. A fuller account of the
Deputy Scientific Secretary with &et fmm the rst February origin and functions of the T m t , intended mainly as a
1963. guide for applicants for grants, has been prepared as a
m n h l e t and is availablefrom the Twt's offices on w e s t .
k e b r e s e n t Report, accordingly, will deal mainly with the
gmnt-makingand other charitable actiritia of the Trustees
during the two-year period which ended on the 31st
The funds which the Trustees were able to allocdte in
1960-62 totalled over Ll,ooo,ooo, as against about
Lr.2oo.000 in 1958-60. As before, i t is important to
emphasize that these sums represent allocations and not
achlal expenditure during the period; they do not necessarily
d e c t a corresponding increase in the Trust's annual
income. The calls upon major capital p m , e s p e d y
thoseforbuildingprojeca, are sometimes spread over seved
years by inevitable delays in planning and consmction.
NOTABLE EVENTS DURING THE YEARS
Henry Doh Pr./~orhip of The Royal Sociep
In M y ,961, the Royal Society accepted a capital grant
of ~ t o o , o o o from the T m t t o endow in perpetuity a
Henry Dale Research Profe~sorship in Medical Science,
commemorating the outstanding services of Sir Huvy at the Columbia-Presbyterian Medical Center New York
Dale, O.M., G.B.E., as the T ~ s t ' s
Chairman from 1938to City. Dr. Adamsons, who is investigating th; respiratory
1960and since then as its Scientific Consultant. It will be function of the newlyborn and the problems of neonatal
recalled that Sir Henry was President of the Royal Sociev asphyxia, holds his fellowship concurrently with the port of
from 1940-45 and that he had served as its Biological Associate Professor of Obstetrics and Gynecology in the
Secretary from r~z,--js. The Trustees have been glad College of Physicians and Surgeons of Columbia U i e s t .
to learn from the Society that Dr. J. L. Gowans, of the R e second of these posts, that of the Herny S. Wellcome
Sir William Dunn School of Pathology in the University Research Biochemistat the Massachusetts General Hospital
of Oxford, who was formerly a member of the scientific Boston, Mass., has been awarded, for ten yam, to D=:
staR of the Medical Research Council, has been appointed Hennan Kalckar, Professor of Biological Chemistry in tbe
to this Chair in recognition of his distinguished work on Hanard Medical School. His work is concerned with the
the immunological functions of the lymphocyte. Professor physical chemishy of cell surfaces, and with the f l e c k of
Gowans is continuing to work at Oxford on problems of genetically determined variations in the sugar pattern of
immunology. these surfaces on the resistance of the cell to v- i.
Further information about: the programmes of Dr. Adam-
Wellmm Senior b e o r & FdIowsh1ps in Cllnlcal Sdenn sons and Dr. Kalckar is given on pp. 25-26.
To encourage workers of proven ability to make careers
in clinid research in the United Kingdom, the Trustees CO-operative Rerearch on Tmpicol Anaemiar and Sprue
have imugumted a system of Wellcome Senior Research
Fellowships in Clinical Science, to which the appointments A form of anaemia characterized by rhe presence in the
are made not in response to direct application by candidates blood of large, immahlre red celb is widespread in t r o p i d
but by selection from a list of nominees put bmard b; counties; and in India and the Far East, although rarely in
University Professors in the clinical subjects. The first AFrica, i t may be associated with the symptoms of i n t d n z l
fellowship of the series has been awarded to Dr. E. H. malabsorption and tropical sprue. Amongst the many
Cooper, of St. Mary's Hospital Medical School, London workers interested in this syndrome have been Dr. H u y
whose programme, akin to that of Professor Gowans a; Foy and Dr. Athena Kondi of the Trust's staff (p 28) the
OxFord, with whom he formerly worked, is concerned group of investigators working with Dr. ~elw; &r in
with the biology and Functions of the lymphocyte in health the Welkome Laboratov at the Christian Medical CoUege
and disease. It is hoped to appoint one or more of these and Hospital at Vellore in South India, and an R.A.M.C.
senior research fellows in clinical science every year, as team at Singapore. Following a number of informal
suitable nominees become available. meetings with these groups a clear need emerged For
p l d g a concerted attack on the problem and for standard-
New Appointmenu in the U.S.A. izing the methods used by different investigators. The
Trustees, with these aims in mind, have agreed to make
In the United States of America the Trustees have pro- funds available for a CO-opentiveresearch programme on the
vided funds to establish two senior posts for research workers subject and to provide a Wellcome Research Laboratory of
of distinction. The first of these was a five-year Wellcame Haematologyat the PostgraduateMedical School OFLondon.
Senior Research Fellowship for Dr. Karlis Adamsons, Jr., This will he part of the Department of Haematology
commemoratine the outstandine services of Sir Henrv at the Columbia-Presbyterian Medical Center, New York
Dale, O.M., G:B.E., as the ~ 1 ~ 9Chairman From ,938 &
2s City. Dr. Adamsons, who is investigating the respiratory
1960and since then as its ScientUic Consultant. It will be function of the newly-born and the problems of nwnaal
recalled that Sir Henry was President of the Royal Society asphyxia, holds his fellowship concmntly with the post of
from 1940-45 and that he had sewed as its Biological Associate Professor of Obstetrics and Gpecology in the
Secretary from 1925-35. The Trustees have been glad College of Physicians and Surgeons of Columbia Univenity.
ta learn from the Society that Dr. J. L. Gowans, of the The second of these posts, that of the H e q S. Wellcome
Sir William Dunn School of Pathology in the University Research Biochemist at the Massachu~etts General Hospital
of Oxford. who was fomerlv a member of the scientific Boston, Mars., has been awarded, for ten years, to ~ r :
staR of t h i Medical Resrarch'~aunci1, has been appointed Herman Kalckar, Professor of Biological Chemistry in the
t o this Chair in recognition of his distinguished work on Harvard Medical School. His work is concerned with the
the immunologicalfunctions of the lymphocyte. Professor physical chemistry of cell surfaces. and with the effects of
Gowans is continuing to work at Oxford on problems of geietically determined variations in the sugar pattern of
immunology. these surfaces on the resistance of the cell to virtues.
Further information about the programmes of Dr. Adam-
Wellcow Senior Ruenrch Fdowships In Clinical Sciencs sons and Dr. Kdckar is given on pp. 25-26.
To encourage workers of proven ability to make careers
in clinical research in the United Kingdom, the Trustees Co-operative Resecrch on Tmpical Anamtior and Sprue
have inaugurated a system of Wellcome Senior Research
Fellowships in Clinical Science, to which the appoinbnents A form of anaemia characterized by the presence in the
are made not in response to direct application by candidates, blood of large, immature red cells is widopnad in tropical
hut by selection from a list of nominees put f o m d by countries; and in India and the Far Ead, although rarely in
University Professors in the clinical subjects. The fint Africa, i t may be associated with the symptoms of intestinal
fellowship of the series has been awarded to Dr. E, H. malabsorption and tropical sprue. Amongst the many
Cooper, of St. M q ' s Hospital Medical School, London, workers interested in this syndrome have been Dr. Henry
whose p r o p m e , akin to that of Professor Gawans at Foy and Dr. Athena Kondi of the Trust's staff (p. 28). the
Oxford, with whom he, formerly worked, is concerned mp of investigators working with Dr. Selwyn Baker in
with the biology and functions of the lymphocyte in health $e Wel,come Laboratory at the Christian Medical & ,
and disease. It is hoped to appoint one or more of these and Hospital at Vellore in South India, and an R.A.M.C.
senior research fellows in clinical science every year, as team at Sinmpore. Followine a number of informal
suitable nominees become available. meetings wig'these groups a clear need emerged for
plming a concerted attack on the problem and for standard-
New Appintmmu in the U.S.A. izing the methods used by different investigators. The
Trustees, with these aims in mind, have agreed to make
In the United States of America the Trustees have pro- funds available for a co-operative research programme on the
vided funds to establish two senior posts for research workers subject and to provide a Wellcome Research Laboratory of
of distinction. The first of these was a f i v e - y d e l l c o m e Haematologyat the Postgraduate Medical School of London.
Senior Research Fellowship for Dr. Karlis Adamsons, Jr., This will be pan of the Department of Haematology
British end of the arrangement. The proposal was cordidly
accepted by the Swedish Medical Research Council, and the
first appointments under the new two-way scheme were
made in respect of the academic year 1962-63 (p. 32).
D ~ v e l ~ p min the Wdlcome Hinoricd Medical Ubrnv
A memorable event of a different kind in the T w t ' s
historywas the acquisitionby theTmteesfrom the Wellcome
Foundation Limited, in 1960, of thecontenwof theWellcome
Historical Medical Museum and Library, as mentioned in
the last Report. During the past year rhe premises for the
Lib? in the Wellcome Building in Euston Road, London,
have een expanded and recrmstructed, and they now
include an American Room and an Orient4 Room, the
former housingthe imporrant collection of books and manu-
scripts relating to the early history of medicine in the
Americaswhich had been formed by Dr. FrancescoGuerra,
formerly Professorof Pbmacology in the NationalUniversity
of Mexico, and visiting Professor of the History of Medicine
d. The Wnllromc Hi,turicrl Yc~lllirrl Libran. Enrrrnec corridor 4 t h
<li,plo? c e .
at Yale University. The Trustees purchased the coUection
from Dr. Guerra, who bas been awarded a Wellcome
Research Fellowship to prepare a definitive catalogue. The
reconditioned and enlarged library (Plates I and 11). now
undoubtedly one of the finest of its kind in the world,
was re-opened by the Right Hon. Lord Brain, D.M.,
F.R.C.P., inSeptember 1 9 6 2 .
11. Research in Human and Animal
T H E field of the Trustees' grant-makingactivity, as broadly
defined by the terms of the Tmst, may be interpreted as
extending to the support of any researches in the biological
or even in the more basic sciences, which can be regarded
H. Thc Wellmmnx Hi\tcrrid Mcdicrl Library. The American lloon?
as having a special importance for the progress of knowledge The Trustees give effect to their policy either in rrspwac
in human or veterinary medicine. So far, the Trustees to specific requests for their aid, or through decisions to
have shown ~articdar.interest in suooortine researches support new ideas which have presented themselves in dis-
relating to ph&nacology, pharmacy, ana;;the~ia:~h~siolo~~, cussions with workers in various branches of medicd
biochemistry,biophysics,experimental pathology and clinical research. In particular. thev have found that their inter-
medicine. includin~oroblems s~ecialto medicine in the. - national mandhe has ekblid them to support work by
tropics. 'They wo;;ldnat, how&=, wish this record to be people of many nationalities, and on occasion to develop
understood as representingan intention to exclude from their CO-ooerative schemes for research in different nam of the
consideration any suitable research project in medicine worfd. Comparative medicine, geographicalp h o l o g a n d
and the allied sciences. special tropical problems are aspects of medical research in
In the last Reoort i t was stated that the Trustee nrincioal
aim bad been to fill gaps in the existing provision for medical
which there are special oppommities, but for which re-
stricted national budzets are normally unable to provide
research and to complement the activities of other g m t -
making bodies. while avoid in^ dudication of these. In The increase in the size and range of the Wellcome
c o m m k with 'other gnnt-givi& o&-anizations they preFei Historical Medical Library in the Euton Road, London @p.
to support new and original projects of high promise, h
I I and 34) has meant that a larger proportion of t e Tmt's
chosen from the many coming to their notice. Too often, resources than before has come to be spent upon its own
however, the funds available to the Universities for the Library. Increased provision has also been made for the
efficient suooort of oresent and oroiected research are con-
and the Trustees have felt obli ed
needs of the associated Wellcome Historical Medical
Museum. In accordance with the terms of their Trust,
to come to their assistance at a time of difficultyimposedgby however, the Trustees have still found opportunities to
lack of nublic funds for exomion. make certain grants for the development elsewhere, and in
An Amination of the dassifiedlist of grants (Appendix B) more than one country, of institutions and enterprim
shows that more than half of the total funds provided have devoted to the interests of historical scholarship in the field
been for buildings and costly equipment for established of medicine and the allied sciences.
departments with research reputations. This is likely to The Trustees have continued to receive. and desire mate-
continue for some time. aince the accommodarion and fully to acknowledge, many useful oppdrtunities fopcon-
equipment of many such centres are regrettably below sultation and discussion with the secretariats of the Medical
modem standards. The cost of much modem research and Agricultural Research Councils. These have been
apparatus is great and Universiry budgeting has not yet most helpful in enabling the Trustees to fame their policies
been generally adjusted for such provision. An unfomr- without embarrassing overlap with what is already in hand
nate result of the present relative poverty of the Universities on behalf of the Government, and in several instances
is a constant need to beg from outside sources for to co-operate successh11y in important enterprises, in-
additional support: heads of active research deparbnents cluding the provision of extra equipment for the Nobel
have to devote a disproportionate share of their time to prize-winning Molecular Biology Research Group in Cam-
seeking financial aid for their projects. This w t e of the bridge. The Trustees have further been gnteful for the
time of talented men can be eased onlv bv a more liberal helpful advice and suggestions which they have received in
attitude an the part of the State to ~nivehitj. research. response to confidential inquiries from so many individual
1 experts about research proposals coming before them.
They have also had welcome opportunities of consultation
and co-operation with those responsible for the administra-
tion of other charities with comparable interests, such as
since the U.K. Research Councils, which cm often meet
the needs of British investigators, are usually unable to
help foreign "isitorS.
the NuRield, Wolfson and Ciba Foundations and the Travelling Research Fellowships have also been awarded
Leverhdme Tmst Fund. to encourage the interchange of workers between countrico
and, as already indicated, the success of the ~ a r l s b e g
Wellcome Travelling Research Fellowships scheme
INTERNATIONAL SCOPE O F THE TRUST'S for Danish and British workers, established jointly with
7%e Will of Sir Henry Wellcome did not impose any
limitation upon the scope of the Trust's exchange fellowships with the Medical Research C o d
assistance to medical research, and the Trustees have them- of Sweden.
selves taken the view that, while the overriding consider- Another type of international co-operation which has
ation in the distribution of their benefactions must always great value is the linking-up of laboratories in developing
be need and opportunity, then, provided the need can be countries with longer-established institutions ekewhere.
shown to be real and the application meritorious they have hs
T i type of co-operation is of mu@ h & , providing
a certain moral obli tian towards countries such as the facilities for the worker overseas and special material for
United States of Ame?ca, in which a substan& proportion his colleagues at home. A special arrangement of tbis kind
of the Trust's income is earned. was inaugurated when the Tmtees sponsored a scheme for
In carrying out their international mandate the Trustees the study of macmcytic anaemia and the malabrorption
have acted in several ways. The Wellcome Research syndrome (sprue) in different parts of the world (see
Travel Grants (p. 33) were instituted in I ~ S S enable
M P P 3 and 23).
experienced investigators in the medical sciences to visit The important appointments established by the Trustees
one another M) as to acquire new research techniques, to at the Columbia-Presbyterian Medical Center, New York
work in one another's laboratories, and to discuss research City, andat Boston, Mass., have alreadybeen mentioned, and
problems of common interest. ' In the period under review reference will be made subsequently to the work in
twenty-seven such awards were made to workers from th; anaesthesia and in cardiovascular physiology which the
United States of America, eleven to workers from Australia Trustees had earlier assisted at the University of Pem-
seven to workers from India; and a glance at the table on pp: sylvania and at the Johns Hopkins Haspital, Baltimore,
54-62 will show that, while the majority of successful respectively.
applications for these grants came from candidates within Some further examples of the international range of the
the United Kingdom, the countries from which other Trust's grants may be given here.
successful applications were received were in fact almost In Canada, Professor J. G. Robson (p. 27) has continued
global in distribution. In awarding Wellcome Research to direct a Wellcome Research Department of Anaesthesia
Fellowshipsfor the temporary personal support of workers at Montreal, and his work has been assisted by a further
within the United Kin dom the T ~ s t e e shave always given grant for equipment. Work on steroids at the University
special considerationt:candidates frnm overseas (see p. 3 r), of Saskatchewan, and on rheumatoid arthritis at the Queen's
University, Kingston, Ontario, has also been assisted. The
Trust has helped libraries concerned with the history of
medicine at Vancouverand at Toronto.
In Aushalia major equipment was given to the Waiter
and Eliza Hall Research Institute at Melbourne, and to the
new Monash University. At the National University,
Canberra, apparatus was provided for work on transmitter
substances at central nervous synapses, and an uloacentri-
h e war. given to the Depamnent of Virology far work on
t : chemistry of uiru3es.
In New Zealand a special opportunity arose, and one of the
Trust's major capital grants (£~zo,ooo) war. made t o the
University of Otago, to build a Wellcome Medical Research
lnstihlte at Dunedin (Plate 111). The University has re-
sponded by creating a special chair of medical research for
Sir H o m e Smirk, the lira Director of the Institute. Sir
Horace's important clinical research work on systemic
hypertension and hypertensive heart disease, and his
associated experimental investigation of these conditions in
"genetimlly" hypertensive rats, will thus be able to proceed
in an improved environment. Facilities for other lines of
research will also be available.
On the continent of Africa grants have been made to
support research projects in many fields. In South Africa,
researches on diabetes and other metabolic diseases, on
problems of experimental surgery and on tetanus, have been
assisted at Cape Town, Johannesburg and Durban respec-
tively. In the Sudan equipment was provided for work on
scorpion venom, and in Southern Rhodesia for studies on
the biology of the tsetse fly. In East Africa the Trustees'
baematological unit, directed by Dr. Henry Foy and Dr.
Athena Kondi, continues to study tropical anaemias (see
p. 29) and Dr. A. Hartboorn of Makerere College was given
a special vehicle to assist him in investigatingenvironmental
factors which may intluence the reproductive function in
wild animals. At Makerere, am, the work of Professor
Cecil Luck on temperature regulation in wild animals has
been aided by the mobile unit provided earlier, and visiting
workers have received support to enable them to examine
kindred ~roblems. Professor D. B. Allbrook received a
vehicle t i continue his studies of primitive skeletal remain.
in Uganda and their possible bean'ng upon the evolution of
man. The long-vacation scholarship scheme in tmpicd
virology, which enables a student from Glasgow Univunity
to visit Entebbe and work there for three months under the
direction of the Director of the Virus Research Institute,
has been continued, and the Trustees have plam for extend-
i w this scheme to other centres as ornortunin offers.
h i t i c a l changes often have unfo-te effe& on medical
research, and the Hehinthiasis Research Unit of the West
African Council for Medical Research encountered such a
hazard. Not only was that Council dissolved as a result
of the attainment of indemdence of the member countries.
but the Southern ~ a m e k o n s ,where the unit was brat2
at Kumba, decided to become part of the Camenun
Republic by joining with the former French territory.
The Trustees had beard good reports of the work of
D . B. 0.L. Duke and his colleagues on onchocerciads
and loiasis, and were glad to be able t offer a guarantee of
support for hvo years, so that the political position might
have time to clear without interruption of this important
study. Fortunately it now seems likely that t i guarantee
will not all be needed. Grantshave been made inNigeria to
several members of the University smff at IMan for work
on nutritional neur~~athies, on bone development in
children, an the chemistty of the abnormal haemoglabins
and an malaria.
In India several manb have been made to Dr. Selmm
Baker at the ~hristi&Medical College, Vellare (see p. j) ;.
Major equipment was provided for Dr. P. M. Bhargava'r
work in protein chemistry at Hyderabad and for Professor
Singb's studies of fiuorosis at Patiala. G m * have &
been made in Singapore for work on bookworm, in Israel
for work on viscea leishmaniasis and malada, and in Hong
Kong, where additional laboratory space was provided for
the Department of Medicine. In Italy upipment was
provided for the new lstituto Fa~macologico "WO Negri"
at Milan, an institute constitutionally similar to the Well- In London, the Postgraduate Medical School at Hammer-
come Trust, whicl~ under the direction of Professor S. smith, after many years in temporary accommodation, has
Garattini. now begun to build permanentlyfor its teachingand research
Grants made in countries other than the United Kingdom needs. The Trustees have heen glad to assist with the
during the period under review exceeded £400,000. provision of research laboratories, and have made p t s
totalling L174,ooo for two sections of the new building.
CLASSIFICATION OF RESEARCH GRANTS These sections will contain the Departments of Virology,
The grants made by the Trustees in the last two years to Tissue Culture and Microbiology, all fields which are being
assist research in human and animal medicine, and in the rapidly developed at the present time, and in which there is
related sciences, can be classified under the following a great need for the provision of research facilities directly
headings: adjacent to a hospital. The Department of Haematology at
the School will also have new accommodationfor its h v h e
(i) Capital grants for building projects.
research, as already mentioned, and the Trustees look for-
(ii) Provision of special research equipment.
ward to the extension of their present interest in
(iii) Support or endowment of senior research posts.
haematologicalproblems in the Tropics, through w t i o n
(iv) Research fellowships, scholarships and personal
grants. with this basic institute, where the training of experts and
the co-ordination of studies can be undertaken.
(v) Travelling research fellowships.
(vi) Grants for research expenses and assistance. The development of better facilities for clinical research
has heen aided at several centres in London. Thw, at
(vii) Travel grants.
King's College Hospital Medical School, the Trustees have
(viii) Grants in aid of symposia, and block travel grants.
contributed £45,000 towards the cost of the new Clinicd
(ix) Grants in aid of publication.
Research Wing, which will contain research laboratories
Full lists of the grants made under each heading will be for the deparunents of medicineand surgery as well as for the
found in Appendix B. From these only a few illustrative Medical Research Council's Research Unit in Pulmoayl
exampleswill be mentioned in the text. Physiology. A p t of E50,ooo has been made t& o the
(i) CAPITAL GRANTS IOR BUILDING PROJECTS rebuilding programme of the Institute of Child Health,
Great Ormond Street Hospital, where biochemical research
New gran* i n 1~60-6z.-Realizing the difficulties too laboratorieswill be w d e r the charge of Dr. Barbara Clayton,
often confronting Universities in raising money to build working on endocrinological and metabolic problems.
laboratories for research, the Trustees have continued to A grant of £lo,ooo t o Charing Cross Hospital Medical School
give aid of this kind where the quality of the investigators provided improved facilities for the Medical and Obstetric
and the promise of the long-term programme have seemed Departments for furdamental research on cardiac and r e d
to justify it. A full list of such grants, totalling £882,950 function and an .several aspects of pregnancy. At
during the period under review, is given on pp. 40-4,. the Westminster Children's Hospital Dr. Percy Cliffe is
Among the largest awards was that of L ~ l o , o o o the Uni- being given laboratory accommodation costing £lz,ooo to
versity of Ohgo, Dunedin, New Zealand, which has been assist his experimental research on the circulatory e5ecu
noticed in the section dealing with the International Scope of congenital cardiac abnormalities; at St. Mary's Hospital
of the Trust's Activities (p. 16). a grant of ~ j , ~ o o been made for the conversion of
I blunenimoms into a mecial air-conditioned Iaborato~ for
work on msitivity rea&ons to antibiotics and other d&gs.
In the sciences related to medicine, the Trustees have
made a pant of up to fss,ooo for a building to house a
linear accelerator which will be used in experimental work
in radiobiologyat the Department of Physics at St. Barth-
olomew's Medical College, London. They have also
increased by Lj3,ooo their grant (of £yo,ooo), made
in 1960, to provide Wellcome Research Laboratories
for the Department of Phannacology at the Middlesex
Hospital Medical School. A grant of up to £6o,ooo will
enable the ZoologicalSociety of London to build a Wellcome
Institute of Comparative Physiology, which will at first be
concerned mainly with studies of the physiology of animal
In Scotland the Trustees undertook to assist the develop-
ment of research in the bioloeical sciences throueh a mant
of £60,000 towards the CO; of a new ~ e ~ a F u n g t of
Genetics at Glasgow University under Professor G. Ponte-
d. Thu sxtrnsion to the Charles H. k s r Instlrutcof the Univenit)ofTomnb,
corvo, F.R.S. In Edinburgh the Tmtees gave £so,ooo to
build laboratories for the study of epigenetics (the biology rvnnuctmd $ bridge to the btlng Inrtirute. ol lack Marshal1Q
(Courtesy . Co. Ltd.)
of vely early development) under the direction of Professor
C. H. Waddington, C.B.E., F.R.S., who direas a Medical
Research Council Research Group in this subject. Two
other building projects are to be started in Scotland with the
help of the Trust: an extension, costing some L16,ooo, t o
the Small Animals Experiiental Research Unit ("Wellcome
Laboratory") at Garscube, originally provided by the T m t
for use by the School of Veterinary Sciencesand the Depart-
ments of Medicine and Surge~y Glasgow University; and
extra accommodationcosting £.~o,ooo for the Gatty Marine
Lahoratoly of St. Andrew's University, where work on the
neurophysiology of simple tnarine animals will now have
Two grants were made to the University of Birmingham,
one (up to f~+.ooo) for buildings for a Neurocommuni-
cations Researchunit in the Depamnent of Physiology, under
Dr. I. C. Whitlield, and the second (up to L8,ooo) to
8. lntcrlor u f r Wrllcomu I~e~rareh
Lobomtory in the nest Institute.
(Cwrtog a l Jack Mamhall % CO. Ltd.)
I 1 proride improved facilitiesfor the Institute of Child H d t h ,
where r e a c h is in momes on metabolic abnormaliti~
which may be a cause dfm&tal ddeciency.
At the University College of North Wales, Ba.ngor, dre
sum of £9,850 was provided for extending the DepKamot
of Zoology so as to accommodate an increased number d
postgraduate research students.
In Dublin two grants for research l a b o r a t o r i e 3 e
to Trinity College, the fimt (of tsj,ooo) to build new
premises for the Department of Biochemktry, the second
(of f3,ooo) to adapt and equip additional space for the
Department of Pharmacology. A grant (of ~16,ooo) to
include space for a Wellcome Research Library in the
BiochemistryDepartment was also made to the College.
Grants to build modem accommodation for laboratory
animals were made to University College, London, Chariqg
Cross Hospital,and the Universityof Oxford. They todled
£81,000, and the cost of animal accommodation was b
included in several other awards. An unusual example was
the new insectaries for researches on medical entomology
at the London School of Hygiene and Tropical Medicine, for
which the Trustees made a grant of Q,goo.
Prosress of buiIdingr ossltdrtpd in earlieryerr.-The pedod
1960-62 has seen the opening of a numba of buildhp
provided through grants made by the Trustss in earlier
years, the most noteworthy being that for the Departmmt
of Radiotherapeuticsin the University of Cambridge, which
Her Majesty the Queen was graciowly pleased to open in
May 1962. These laboratories form part of a fine new
building on the Addenbrooke's Hospital site, which also
houses the Medical Research Council's Laboratory of
Molecular Biology (p. 2 3 ) .
The extension of the Charles H. Best Research Institute
of the Universityof Toronto, to& the cost of which the
Trustees allocated £70,000 in January 1960, h MW in
active use (Plate IV). The Wellcome Research Laboratory
in the Department of Medicine at John Hopkins Hospital,
Baltimore, U.S.A., the grant for which was made in
of the award of the Nobel Prize for Chemishy in 1962 the molecular shucture of certain cmpwnds. Special
jointly to the Director of the Laboratory, Dr. M. F. Pemh, items of apparatus needed to measure the optical density of
F.R.S., and his colleague Dr. J. C. Kendrew, F.R.S., and d cell nuclei, the mineral content of bones, the electrolyte
that for Physiology and Medicine in the same year to Dr. content of blood after operations, the viscosity of pharma-
F. H. C Crick F R S. workin there 'ointly with Dr. M. ceutical preparations, the natural radioactivity of substances,
H. F. Wilkins,' F:R:s.: of the%.R.d.'Biophysics Unit at the pressures in various vital systems, and the amino acid
King's College. London, and Dr. J. D. Watson, who recently content of solutions, have also been provided.
worked with the g o u p at Cambridgeand has now rehlmed
to Harvard University, U.S.A. To assist the unit at King's ' In Italy a special block p t to purchase research equip
ment was made to ProfessorS. Garattini, head of the Istituto
College, London, a grant had previously been made by the Farmacolagico"Mario Negri" in Milan. The Trustees in
Trustees far the purchase of the lease of a building to this instance were glad to help a sister foundation, created
accommodate its new laboratories. under the will of Canleri Mario Negi to devote the prolib.
In the period under review some twenty-six different of the pharmaceutical firm of Farmacosmici to the founding
types of major equipment have been provided in response and support OF a research institute. The investigations of
to individual applications, those most h.equently granted Professor Garattini and his colleapes in the Institute include
having been electron microscopes ( 9 ) , ulhacentrifuges (7) the testing of dmgs against experimental bsnous, and
and various types of spectraphotometer (12). The re- studies of the phmacological properties of biologid
searches for which the nine electron microscopes were amines.
supplied embrace studies of the comparative anatomy of the I Recent manb for the nurchase of vehicles to assist the
ear, the synapses between nerves and muscles, the physi-
ology of helminth parasites, histochemical studies in tissues,
skin pigmentation, the strucolre of nerves,the fine structure
!1/ conduct orfield -arch& in Africa have been mentioned
in the section dealine with the intemationd scope of the
Trust's activities (p. ;G).
of the digestive tract, and pathological changes in lung
structure. The ultracentrifuges have been provided far
studies as various as some on synaptic transmitters in the
:I (iii) SUPPORT o n ENnowMsNS 0 s sEN10R
brain, others on viruses, on th; p&enomena of immunity, (a) New Appolnvnmu
and on the structure of proteins. Fluorescence microscopes
have assisted the study of varioug problems of immunology. The endowment by the Trustees of a Henry Dale Research
Special X-ray equipment has been given to Guy's Hospital Professorship For the Royal Society has been mentioned
for clinical research an the metabolism of carbohydrates in on p. 7, as has their establishment of senior research
the muscles of diabetics; to the Christian Medical College posts at the Columbia-Presbyterian Medical Center, New
at Vellore, India, for studies of the intestinal tract in sprue; York City, and the Massachusetts Genenl Hospital,
and to the Rowett Research Institute at Aberdeen for use in Boston.
nutritional and other investigationsin farm animals.
Much of the equipment supplied has been used in bio-
chemical investigations of various kinds. Two major
p t s were made for the purchase OF nuclear magnetic
I Wellcame Research Fellowship, which is tenable for fivs
years, concurrently with M post of Assistant Professor d
resonance spectrometers, which are required to determine Obstetrics and Gynecology. With Dr. L. Stanley James,
24 l 25
Associate Professor of Pediatrics, he has been investigating formed only if the yeast is g r o m on a medium containing
various aspects of foetal and neonatal physiology with the sugar galactose. Dr. Kalckar and his colleagues have
assistance and research expenses provided through long- found many micro-organisms which have metabolic defects
term programme grant from the National Institutes of like those seen in the congenital disease of msn called
Health. Their researches in 1961-61 have been can- galactoraemia. Thus, these studies of rrjcro-organisms.
cerned chiefly with the effeas of different thermal environ- especially of the biochemistly of their genetics, may provide
ments upon the recovery process from birth asphyxia and fresh ideas for studies in human biochemistry,
acidosis. Various factors influencing the metabolic rate in
newborn infants have also been examined. in parallel with (h) Rerearch in Anoduia
their clinical shtdies, Dr. Adamsons and Dr. James have It has been mentioned (p. 12) that research in -thepia
investigated problems of neonatal asphyxia in guinea-pigs was one of the subjects to which the Trustees decided to
and in rhesus monkeys. The studies in monkeys have been give attention when originally planning the range of their
made in collaboration with Dr. G. S. Dawes and Dr. grant-making activities. Since 1956, they have supported
Michael Dawkins of the Nuffield institute of Medical a Wellcome Researeh Profesror of Anaesthesia (Pmfessor
Research at Oxford, using the facilities of the primate J. Gordon Robson) at the McGiU Univenity, Monpeal,
colony of the National Institutes of Health Laboratory of Canada, and a Wellcome Associate Professor of Anesthesi-
Perinatal Physiology in Puerto Rico. ology (Dr. Henry L. Price) in the Universityof Pennsylvania,
At Boston Dr. Herman Kalckar, who holds, for ten years, Philadelphia, Pa., U.S.A. Like other grant-making bodies,
the post of Henry S. Wellcome Research Biochemist at the the Trustees are gratified when a project which they bave
Massachusetts General Hospital, concurrently with his financed during its initial stages proves so successEul as to be
chair of biochemistry at H w a r d University, has been carried on thereafter by the host institution. and they are
investigating the inter-relations of cells in higher organisms happy to be able to report that that is occ"rring in'hoth
with special reference to the chemistry of the cell surfice: these instanca. McGill University has already made
His studies of surface chemical relations have been assisted additional provision for Professor Robson's department in
by the discovery of some bacterial mutants which lack most 1962, and will assme the rcrponsihility for its maintenance
of the normal sugar patterns in their cell walls. The after the Trust's grant comes to an end in 1966; in the
altered cell walls do not collapse, but they give the cell a meantime the Trustees have ameed to make a further non-
different biological profile. . it is interesting that this recurrent grant of £6,000 to Professor Rohson for the pur-
different chemical mosaic is reflected in the response of the chase of electronic recording equipment needed for the
cells to viruses. The biochemical mutants are protected present stage of his prognmme. Dr. Price, whose support
against attack by certain viruses because the latter are unable from the Trust will end in 1964, has meanwhile been
to penetrate them. The basis for the altered surface mosaic appointed t o a Cull Professorshipin the University of Penn-
is a defect in a metabolic e w e . Some of these abnormal sylvania, and the University has given h i improved
enzymes are being investigated in living culhlres of human lahoratoly accommodation with the promise of continued
and mouse tissues. The molecular structure of enzymes suooort for his new deoamnent.
is being examined by new and highly sensitive methods ' ' h e prognmme af'~rofessorRobson and his colleagues
which exploit the phenomenon of fluorescence. By this has been mainly concerned, in the last two years. with
means an enzyme has been demonstrated in yeast which is
indirect, in thst although the Trust has provided funds m
establish and maintain the post, the worker has been
appointed and employed by the recipient institution. The
appointments of Dr. H n y Foy and Dr. Athena Kondi are
in a different category. For reasons mentimed in the First
macmcytic anaemia. Dr. S. I. Baker, of Yellore, was one
of those from overseas who paid working visits to the unit.
Co-operative studies have also been undertaken with other
groups and individuals, making use of the Fpcilitics of the
unit for radioisotopework.
Publications from the unit are listed in Appendix D, and
Plate V1 shows the n m research library provided by the
Trustees for the Laboratoryin Naimbi.
( h ) RESEARCH BELLOWSHIPS, SCHOLARSHIPS 60 to thirty-two at present. T i expansion W already
AND PERSONAL GRANTS indicated, has been due chiefly to the provisioA of support
for workers from abroad making visits to the United
(a) Delegated Awordr Holders of Wellcome Research Fellowships awarded by
The Trustees have continued to assist research training the Trust have come to Great Britain from the following
in veterinary medicine and in pharmacy and pharmacola countries: South Africa four. Australia six Japan two.
by making block grants to the Animal Wealth Tmst and Yugoslavia one. ]mai; on; India th;ee. 'United sa td
Pharmaceutical Society of Great Britain, rerpectively, far ~ i
of ~medc;, tw;; ~ a l a twd; ~ g p ' t ,two: Nigeria, one;
the provision of Wellcome Research Fellowships in these Eire, one; Argentina, one; and Nyasaland, one; ten such
subjects. There schemes have been very successful. Recent appointments have been given to U.K. workers. A list of
surveysshowed that of the 26 Wellcome Veterinary Research the awards, amounting in all to frr7.739, is given on
Fellows to date, r 5 now hold Universityposts and five work PP. 49-51.
in Various institutes for veterinary research, one being a
Director of his Institute, one a Professor and one the D a (V) TRAVELLING RESEARCH FELLOWSHIPS
of his Facdhi. Of the ~r Wellcome Pharmaceutical
Research Fellows appointed since 1 9 ~ six are in academic
. The Trustees have continued to provide funds to enable
positions and eight hold research posts in industry. That the Medical Research Council to award five Sir H n y er
so many of these hand-picked recruits to pharmacological Wellcome Travelling Fellowships each year to candidatu
research should find permanent positions with progressive of approximately the rame status as those receiving other
pharmaceutical manufacturing firms is, of course, only to research fellowships at the Council's disposal. The arrange-
be exnccted. ment, involving an annual expendihve by the T m t of
Vacation scholarshipsfor training in biochemical research f ~ l , o o owasmade for five years from 1961.
have again been awarded to two students each year in the Occasionally travelling fellowships have been awarded
University of South Wales and Monmonthshire. directly by the Trustees to enable suitably qualifiedworkers
to carry out investigations or to acquire further research
(b) Awordr mode dire+ l the T m ~ e e r
y experience in fields of special interest to the T m t . Nine
such fellowships were provided in the period under review,
The establishment of the Wellcome Senior Research n
five of them for British subjects, two for-I
Fellowships in Clinical Science and the appointment of for a Canadian and ane for a Hungarian.
Dr. E. H. Cooper as the first holder have alreadv been
mentioned (p. 8j. Corlsberg-Welkome Travelling RprCarch FeIIowship
The Trustees have awarded an increased number of
Wellcome Research Fellowshias and Schalarshioa in other The arrangement, mentioned on p. ro, between the
fields during the period. Thui, the number of hew awards Carlsberg Foundation of Copenhagen and the Wellcome
has increased from twenty-sixin 1958-60 to thirty-seven in Trust, for the awarding of research fellowships on an
1960-62, and the number of awards approved in an earlier exchange basis, has continued. Dr. Emil Poulsen was
period but still effective has increased from eleven in 1958- rm
the Carlsberg-Wellcome Research Fellow f o Copen-
hagen during this period. He worked with Dr. 1. M. where this has been necessarv. Such arraneements have
Barnes at the Medical Research Council's Toxicology accounted for most of the &ts under this h h i n g during
Research Unit at Carshalton, Surrey, studying the neuro- the periad under review. O C C ~ J ~ O M ~ ~ ~ special
toxic intluence of alicyclic compounds. Meanwhile two problems have been presented which have required more
British Fellows, Dr. A. F. Hayward and Dr. S. L. Rowles, substantial assistance in the form of expenses grants. Such
were in Copenhagen working respectively on the electron a case was that of Dr. S. J. Baker @p. g, 17, 24) who has
micmscopy of pinocytois, and the role of calcium phosphate chargeof &eWeUcomeSp~eResearchUnitatVellore.The
in the metabolism of oral tissues. entire expenses of his current investigation are being pm-
It has been mentioned on p. 1 0 that, at the end of the vided bv the Trust. and the Trustees ameed durine 1961 to
period under review, Sir John Boyd and Dr. P. 0. Williams, c o n h i e their support to his unit fo; a further gve-years.
Deputy Scientific Secretary, paid an exploratory
the T ~ s t ' s The Unit, in addition to its main programme, has recently
visit to Denmark in connexion with these Fellowship. had an ooDorhmihl to investipatean 'eoidemic' of the SDNe
They were received with the greatest kindness by the ~~ndrom;&lvi~~ some jo,".o peopie.
Chairman and other members of the Carlsberg Foundation, Another major grant for research expenses (£6,000 over
and the dehiled information they were able to gather three years) was made to Mr. W. J. Dempster, of the
about the opportunities for different types of biological Postgraduate Medical School of London, to assist his studiu
research work in Denmark should prove valuable in advising in the tranmhhtion of human oreans and tissues.
future British candidatesfor these awards. G m t s f i r research expenses &d assistance during the
periad amounted in all t o £23,298; they are listed in
Rolearch FelIo1~1hlps Appendix B, pp. 53-54.
The arrangement between the Medical Research Council (vii) TRAVEL GRANTS
of Sweden and the Wellcome Trust for a reciprocal scheme
of Travelling Research Fellowships for Swedish workers The Wellcome Research Travel Grants were initiated by
and workers from the United Kingdom has been noticed the Trustees seven years ago, and their object has become
an p. 10. The fist two Wellcome-Swedish F e l l o w s well known. During the period of this report some
Dr. Tbomas White, from Lund, and Dr. R. G. MahafFy, £.60,000 has been spent in helping j r z research scientists to
from Edinburgh-took up their appointments in the autumn travel to meet colleagues, learn new techniques and carry
of 1962. As with the Carlsberg-Wellcome Fellowships out researeh programmes. A full list of those receiving
for Danish and British workers, the scheme will operate these awards is printed in Appendix B, pp. 54-62.
for five years in the first instance, the individual fellowships
being normally tenable for one year. (viii) G R A N T S I N AI D OP S YMP O S I A,
AND BLOCK TRAVEL GRANTS
(*i)GRANTS FOR RESEARCH EXPENSES AND
In continuation of their policy of supporting small
scientific symposia at which a limited number of m p e m
As indicated in earlier reports, it has been common assemble to discuss the research aspects of particularmedical
practice for the Trustees to make a modest allowance for and biological problems, the Trustees have made grants
totalling rj,qoe for a further five such meetings. Occaaion-
ally the support has been given in the form of a block travel first task the consideration of plans for expanding md
grant, and this method has also been used on the com- refurnishing the Wellcome Historical Medical Library. A
paratively rare occasions when the Twtees have agreed to plan put forward by Dr. Poynter, the Chief Libnrian, in
provide assistance to international congresses dealing with the spring of 1961, was approved and put into effect so
subjects in their fields of special interest. They are in rapidly, thmugb the co-opeation of the staff of The
general apposed to the provision of more than token support Wellcome Foundation Limited and the staff of the Library
for these large meetings, since they take the view that itself, that Lord Brain was able, as mentioned on p. I I to
smaller intimate symposia, attended only by a limited declare the enlarged Lib- open at a ceremony U & ;sth
number of experts, are likely to be fir more effective as September 1962.
aids to research. The Library's collectiom of manwripts, printed books
pamphlets, journals and autograph lemn, going b&
(ix) GRANTS IN AID OP PUBLICATION many centuries, make it one of the most c o m p r ~ v e
special libraries in the world, and i t has rapidly become an
The relatively small circulation of esoteric scientific
international centre for study and h- in the history of
publications is often a bar to their commercial success, and
medicine and its related sciences, a field which provides a
the Tmstees bave continued to assist the communication
of ideas in their field by providing grants or guarantees bridge between natural science and hwnanistic studies. A
catalogue has now been issued of all the books in the library
against loss for the publishers of monographs which are
printed before 1641, and the first volume of a catalogue of
thought to be sufficientlyimportant from the research point
Western manmcrivts on medicine aml science has also
of view or in relation to the history of medicine. In some
appeared, containi& detailed descriptions of some I,ZOO
instances the Trustees bave agreed to meet the cost of ex-
p n i v e but important illustrations. The launching of two works witten before 1650. There is a special coUectionof
new periodicals has also been assisted by temporary g u m Oriental manuscri~ts.of which a catalorme is in th. amme
of preparation, &d adjoining this is the ~ m e r i - R &
tees. A full list of the allocations under this beading is
(Plate b ,) housing the library's now rich collection of m l y
given on pp. 63-64.
Americana. This has recently been greatly increased by the
purchase of the valuable collection of Dr. Francesco Guem,
as already mentioned on D. I I .
111. Medical Research Museums and The w ell came ~ i s t d r i dMedical M n s m has con-
Libraries tinued to exhibit representative specimens from its large
collection, and a special exhibition of the History ot
I N the last reDort the Tmstees mentioned that they had Diagnostic Instruments was opened by Sir Geo&y Marshall,
acquired direc; ownership of the contents of the welicome K.C.V.O., on the 9th May 1962. Amone this Museum's
Historical Medical Museum and Libraw, and that i t was their exrramunl activities was &c setting up, thc request of
intention to develop these in such &hion as to make fully the President and Council of the Royal Society of Medicine,
a d a b l e the great collections which had been largely of a larer exhibit on thc occasion of thc celebration to mark
amas~ed Sir Henry Wellcome himself.
by the juglee of the opening of the Society's H o w . 'Ibis
To carry out this plan effectively the Twtees formed a exhibit was visited by Her MaiesO the Queen. The staff
Museum and Library Committee, which undertook as its
Dr. Edwin Clarke, who held a Wellcome Research APPENDIX A
Fellowship in the History of Medicine at Johm Hopkins EXTRACTS FROM THE WILL OF SIR HENRY
Hospital and University, Baltimore, U.S.A., was offered an SOLOMON WELLCOME
Associate Professorshipin the History of Medicine at Yale in (dated 19th kbruy. 1931)
1961, the Trustees were glad to learn of his appoinhnent
to this important teaching and research post. It will be S IR H E N RWELLCOME b3 Wfl vested the whole of
recalled that before he went to America he was for a time
Assistant Scientific Secretary of the Trust, but resigned in
, the shar= capital of the Wellcome Foundation Limited in
his Trustees and, after providing far certajn personal and
order to cultivate more intensively his interest in medical
I specific bequests, directed that the whole of the dividends
declared by the Foundation should, for all time, be dwotcd
Apart from their expenditure on the support and by his Trustees to the followingpurposes:
development of the WeUcome Historical Medical Museum
and Library, the total sum allocated by the Trustees during I. ".. . the advancement of ru-h work 6eu5ng upon
medicine surgely chrmirtry physiology bacteriology r h n r p t i c .
the period under review to aid research in the history of m t a l r m d c . phannacy and allied subjects ad my subject or
medicine and its allied sciences, and the publication of the 1 mbjecto which have or at any time may develop an imp* for
results of such work, was r 4 , 9 .
2.40 scientific march which m y conduce to the impmvcmmt of the
phyaial conditiom of -kind and in @c& for t e dirwuy
invention and improvement d medicinal agene and methods for the
prevention md sure of &den md the eontml or a k m h t i o n d
imsct and o r h u pento which a I e t human Wigs ad dmd
1 plot life in uopial and otherm@omand eIrc&re. . . "
2. ".. .the eshbllahment and endowment and fuhlrr maim-
fupnce of any new R e v a d Musemm or Libraryand for &c
and acquisition of book manmaipts d o ~ m e n h ~rru.rr ad ohcr
, work ofrrt and other objectoand things far such RcsarchMuvuma
or ~1b-e~ and for conducting r e d s and ~ n ~ ~ t inform- ing
tion connected with the history of medlcine aurgslr &emiray
bacteriology pbamcy and allied seimcu .. .wuy Raeufh
Muaeum or Library for the time bdng main-d .. .aull k
c a n i d o n under the titled "The Wellcome R d Museum" or
"The Wellcome Ruearch Library" or uuh othcr titk id*
the name "Wellcome" u my Trustee m y deem most appmopri-
ate . . ."
A P P E N D IX B i (m) St. W Hospirrl, Landon: To caovattnm bu.bu.t
morminin l b o r u o r l u (Ocmbu 196,) . . Upm
LIST O F G R A N T S (d) TTriolg Callcgc, Dublin: To exand a d rrrcrrch
DURING T H E PERIOD UNDER REVIEW Irbontories f m thc Dc-mr of P b u M m l a a
- (xvli) %m&~6glidmn'i HL~rrl,
and +p praursh -mmodrtloD
G: i2 To
RESEARCH IN HUMAN AND ANIMAL MEDICINE
ofCIiolu1 M W a . .
(xviio Uvi?emlty ~fBlrmin+: T o b u U d - d t i o n f m
the N c u m ~ o m u n i ~ l mR h Unit 0 9 -
(XI.) c o i g C Horpit.i iondiU%!
mTd. the eor of a C l i n i d Ruurrh Wiog (Much
,962) . . . . . . .Upm
U u i ~ ~ l i ofq GLlpOw: TO u a n d the S d
Expcrimmrrl Rcsrareh Unit PNeUmme h r r t o ~ i
.t'cuy:ubc (July #SS.) :. . .U&
(=l) UDLvcr.lty ofEdinburgh: To bvildr l a b o r a q t o how
anew unit for m u r c h In epigtnctiu supported by&
M c d i d R a d CouncU (July 1962) . . Upm
(ull) Univcmlty of St. M r c w ' s : To pmvidc nrrr rrscareh
apcc r the Gltty Marlnc Irbonm'y Uvly 1962) Upm
(uill) C b r y Cram Haapiml Medial L h m l Landon: To
provldc ~ b o r a m r y
mcommcdntirn for & ~cputmcnt
~fobstetrlaand y m e m I o ~
G (luly ,961) .
(=xi.) London School of Hyglcnc and Troplcll Mali&: T o
CoM~etncW!nxc~cl(Ju~y 196%) .
Dcplmncnt of P h y r l o b ~ , Oxford Unirmlg: To
mnhge the Unlvcmlry~ u l m i s ~ f l o n ,962) Up m
I) Proddoo ojSpldol Rmorrh Epvlpmenr (OS G$ m boo):
Appllmor nod Appmam h w
Phu o W d
(I) Profuror F. J. h e r . h l @ a l ulmrcnm- Up D rxo.ooo
F.R.S.: John Cunin fug=
Sehml of M e d i d
(11) Dr. B. P. M-lon: Ul-lcraomc md Up m
Vinu Labomfory d scrrumiu
Public H d t h L.boram7
(=d) Profuor Ruocll h e r : Douttomcter up m tj6, (axvlll) Dr. D. P. C u t h b o n , Up m rro.so.
Dqt. of Endarrln011gy. C.B.E.: R o n m
Sdrwl of Londoo
(=W Pmf. C. H. Gray: U q ~ ~ d . d n u l l ~ f ( up m
~~ rr,jso High lrroludon Up to £ 8 4 , ~ ~
Dcpt. of Chcmiul mpccrmmcta dcctmn mi-op
Nuclear ~ g n e t i s Up m tr+,soo
m m E L
hd Rover md up m 4.000
(nix) Dr. Honor B. Fell M i w ~ and u Up to E9,o.o cxp-
F,R,S,: 0th.. cq#lpmmt
(m)Dr. R. E. Moo-: Dept. SpcetmRuodmctcr Up to rr,jtr Double.bum d o up m y,~.~
ofPhyddogy, Royal rccordlng
Free Horpinl School of spmpbommeter
Mcdidn~.London Spocmphom- Up m rl.f.p
( 4 ) "Df-or C. W. L. spcctmphotom.ter up to qlroo , fl"0rimcmd
Bcvm: Dept. of neau~dca
a . m L q , Uoivcnitg
Collegc, lbrdm, Phommrar, Up m rsoo
Nigeria cmtlccge md othcr
( m " ) Dr. K. S. Dodgson: Autom~tie cqvipmt
Dept. of Rimhonirtry, chramatogne& Up
Univmity Collap of cqvipmmf up m tr,ooo
South Walu rnd Aumdc
Monmouttuhire. G W n f I
(miii) Dr. I. C. Whitfield: bvld.pol up ssoo "I~CD
Arulytlc.1 f l l fmd~
~ U p m rln,ro6
Dept. of Phy~iolagy, rudlometdc cubicle
Univenity of scculod~
( 4 " ) Mr. S. A. Buncn: cold mom up rssr
: PZ g u ,m
2 . L c
Univcrriry of C h p , " Miaowop.. Up" 9.000
( 9 Dr. l. R. Eabr, F.R.S.: vscmm mpontar
- miaommc m d
Dept. ofZoology, m d rrMlodcr up rccuurrica
uvivcnity of O d o d
Blood volmc up m r l , p
(-i) Dr. E. A. Dodge: Rdobompc up g,,j63
~Ithgtnn Hmpiml, cqvipmmr
1 Dr. I. mopphic up m r ~ ~ , . . ~
Photanlaovop Upm E*.,%
ChrMm Mdkal qpipment : a othcr eq"ipmt
Collcp, Vcllorc, South
(hiii) Pmf-r J. G. Roblon: EIecmrdc e q n i p m f Up to u,aoo
(Ill) Profeuor C. Bmvmlrr: S p h a p h o m . Dcpt. of b t h c r h ,
Dept. o f P b o I o a , Uuobm McCill UniverslN.
King's College, London M..tZd, d.
@l) Pmfcuor S. R. Eldcn: Automatic &tion (MM) Prduaor l. Bamtcln: SdntULtim Up t o rzeSwo
~;~,"$~;,"~~ Eomtcr Dept. d B l o c h e m b q ,
M o d Unlwriy,
s p c c a n n u l r .nd
( 1 4 o r . S. F. DCQ~.
Unlnnlty S-opoLr1mtcr Vlctorh, A d i n - m - .
of Chcmlnry. (h) ].
(17) Pmfcuor 0. E. V m u m cnponmr
FTofcuor W. H.
Dept. af Experimental
LowouWn, F.R.S.: .nd u c u a r l a
Dept. d h l w ,
(Id) P ~ ~ C U O C U O
lnrin hlrry'r Holpitd M e d l d
Hilllard: Dcpt. of ?,"::clntiuation School. London
Mcdieinc, Univuniity d (hi!) Dr. W. P. a n : DovMehnn upm
Slrkrtchcm. Dcpt. d Radiology,
(Ivll) P r y o r E. shottan: Rhrngmr(~~.m
univenity C ~ I I I I ~ ~
Dept. of Phrmaceutio,
School of Phumuy,
(MiO P.d-. W. C. W. Photomiaorcop
Nkon: Obstetric Unit, m d other equiprat
(Ux) Prd-V C. Bclpvln: Two npetro-
~ c p t~ f e c t e r l ~
~ ~ ~ , .nd m Mcd1c.l Rcaareh,
Univenlry Collcgc dhrc..trUugc mto. Mclboumc, Aurtralla
Hospital M d l d On)Dr. D. C. Curworth Amlno acid uuly.cr Up to Lx.po
Wlaol, Landon m d Dr. R. c. w u a :
() Dr. 1 C. C. Gleddge:
1. Olcillorope and Drnt. of Humm
Dept. of P h ~ l o l w , -1lluy equipment &Lhol!,m, Unlvemiy
Royal Fkc Hmp1r.l College Hoapitd
School OfMcdlsine, M c k l Sehool. Mori
landan ( d o h r A. lggo:
I)R Elcctmnlc eqnipmcot up m rS,-
(Id) R o f w o r D . B.AUbmok: h d R o v u h p t . of P h ~ o l o ~ ,
b l (Dlck) School d
Univcnity d o f i o r d
( h i l l ) Dr. D. H. M. WooIIm: Photomicmrmpc Up to fr,3oo
h o m r School. (+) ResearchF r l l d l p c , 5ddarYp1 aodPe-01 mu
Gram ( h tbmfor d ~n
" " .of &brldF
i .. $ the Hlmry ofMedldnz):
W v ) Dr. R. S. Duffand Dr. A p n m for Up m tr,ooo (S) Ddcga*d Award':
R. W. B P. :
- mwummurt of (l) The AAoiml H d t h T w t : Wdlcomc V c e d n y
Dept. of Mcdislns, ardlae output
R u m h Fcllowrhips: es,ooo pcr -m Br rhrrc
Unlnnity of ShcRidd -
y fmm the rrt O c m k 1961 (mntlndon d
(h) J. Bdcn:
Dr. J. ~ 3 1 1
Rowcn Research brt.,
Clmatrt (11) 'p *
g" G l&lW .Df GIIIt h*: ," L's.oDo
Wellcome PhuMcolUcal R c l d k l l w n h l p -U-
( h i ) h f a r o r C. P. Luck: Egulpmcotfor Up m q,,,, ally for three y
- fmxn April 1962 (cwflnurfion of
Dept. of Phyaiology, crrd1ovucul.r
Unlrcnig COUrge of r u d
h t AWa
(Lxvil) Rof-r W. B . Nucler magnetic Up to Lno,rra
Whdlcy : School of remmo
Pharmacy. Landon apcc-ttrr
(Ixxvlil) Professor J. 2. Young, Electmn mlmreopc Up to P ~ , , O O ~
F.R.S.: U d v c n l g
College Lmdnn @) Axordd Tr- bfom f i r 3 m AugvD 1960 and r&nh 196042:
( h h ) Pmf-r G. M. Elcctronmlcmscopc Up to t ? ~ , ~ ~ ~
(N~m;m"m~;Fl.rrojwork;mb]~;~ ~ p u l o d g ~ u n )
Wvbum: Uniuoain of
GLgnw ' (l) Dr. C. A. H w c , F.R.S.: U X : London: pmmzoology: rgn-63.
(I-) P d e s o r G. H. (11) Dr. I. de Burgh Daly. F.R.S.: U.K.: O h d U n i n n l g : clp.i-
Eningrr; Qucol's m 4 phpl-logy: 1957-69.
Unlvalty, Onurlo, U
( 0Mn. M.dcleln= G l m c r : U.K.: R r l & h M w c u m ( N d H i . w y ~
*. plmoncmlogy: ,917-6,.
( I d ) Dr. Aubrry L c a b m : (1") Dr. C. Osorlo: Spain: P o s g d u U c M d d Sehool 4 Imdon:
St. G e o v ' s Hmpiml,
( h l l ) Pmlenar I. D. Sln6h:
t h p l d phplology: 1958-60.
(v) Mr. K. Vkkemm.: U.K.: U n l n n i , Col&- london: o
n . -
Mcdlul College, ("1) Dr. R. U U.K.: SaUlbq, Southern Rh&L:
PIU&, hdla mmmmlogy: lgsa-61.
(~11)Dr. k o n d W. Cohm: c n : Dept. d P h m a d o g l md
Thsnpcudu, Unlvcnlty of Mmimh, Wlnnipg: b l a h r m i n y :
(dN) Dr. G. D. Bmrdhad: U.K.: S M d d "isrnity: r d g:
+m o l
(3) Gronujm lk&obll~hmnt ondNolnmann o j s d o r b r r h Appi,,mm: September 1958-63.
(l) I h c Royal Soeicty, Loodon: H q Dale Pzofaronhlp of (h)Dr. J. vm den Bosch: H o k d : The Gdmn h h w y . Unirnrity
th.Royal SaJety, Lrruurch in mcdiclnc, phy.felogy or Collagcbdon: h u m a n p e t i t l : 1 9 6 ~ 6 1 .
phcslogy . . . . . . . L,0.,.00
(X) Mr. Y S. W l c : U:
O f i d : ph-~0!0gy:
Dcpt. of Phmmology, "ircnlty 01
,962 Rd-r J. L. Gawmr (Sir Wllllam D- School
($11 Dr. AUU Dlmitrldou: Gmcee: P o a t d r a c M & d S b l of
(8) Wdlm~.",%o'Z2%SIIWin CIMdScicnce . c 2 0 , ~ ~ ~ ' London: eJld0ahbgy: ino958-62. -
i s 6 l Dr. E. H. C o o p r (St. M q ' s Hoqlal, Landon), (ji) Pmfuaor D. Kcilln. F.R.S.: U.K.: Moleno Inrt. of Blologl md
for Rc y u n , wlth pp r .
P-irology, Udvcnlty of Cunbrldg.: blodraniury; rgsg-6r.
(~111)Dr. J. A. m m ; U.K.: Dept. of P ~ ~
b "isrniy ,
M o d : pl!mmxoIogy: 1 9 6 6 3 .
(XI") Dr. L. F. T a b : U.K.: Iandon Schml of H y g k md TmplPl
~ ~ d l d np u:u l m l ~ g y :1g60-63.
(m) Dr. Angcla Tguloi: U.K.: Qucm Ellnbcth College, Unlvenlty of (m) Dr. I. H. Horn: U.K.: Dept. of Mctabokm and %log.
(rvl) D . A. Zbrmynm: Poland: hbonitolre de N~mphyrlologic,
r Portgraduate Medical Slhml of London: physiology: A p d 1961,
H8pltal Henrl-Rowlb. P u b : ncurophysiology: 196-61. (rvl) Dr. R. Hollomy: South Mica: Dcpt. of Mcdldnc, u a l v s l i y d
(xvll) Dr. B. Jaduon: South Africa: Dcpt. of Medldnc, Univerriv of
Natd: b p t l u : M a y 196r.forh.oyan (with-).
Natal, Durhrn: cliniul r u u r c h : ,960-61. (xvil) Dr. E. M. Till: South Africa: BdtirhMvcvm ( N d %, )
(mill) Dr. J. P. Chrirtophc: Bdglum: M. R. C. Expuimcntd Radlo-
pathology Rerurch Unit, Landan: b1ochcmi.q: 1ggg60. Lordon: entomology: Octabv ,961, fornincmonth..
(xix) Dr. R. K. M l m : Indb: Inrtlmtutcof AnLnal Gencttu, Univcnity of (mlli) Dr. Hkort A. Kurlyama: J r p : Dept. dPhumuology. Orford:
Edinburgh: g a c t i u : ~960-6,. pharmacology: M8y ,961, for one yur.
(Ar) Dr. M. W. Smith: U.K.: h . Animal Phplology, h b n h ,
(U) Dr. W. D. A. Smlth, O.B.E.: U.K.: Dcpt. afAmuththtlm Royd
College of S u g o m of England, Loodon: a n m t h u h : 1 9 6 & , h b d d g c : phyalology:May ,961, fortwo yam.
(-1) Dr. D. H. Treble: U.K.: Dcpt. of Biochembq, Unlvmlv of (U) Dr. lOdl8 A d l M ~ m Jr.: U.S.A.: Dcpf. of ObsflhiCI d
Cambridge: biochcmlrtry; rg6o-61. cology, Colmbla-Pmbytedan Mcdlol Ccnm, N c r YorL City:
( a l l ) S k Chrisfophcr Aodrcwer, F.R.S.: U.K.: prcpvrtlon of book on Jme x g 6 ~ , f o r f i v ~ y ~ .
VlmuafVcrtcbmfer: 1961-64. (=l) Dr. I. B. P- U.K.: Dcpt. of PbYrmsolqgy md Thsrpcutlo,
Shcffidd Unlvmiry: endoainology: Juoc ~ 9 6 1for h e y - .
(c) Awarded b rg6-62: (~11) Dr. J. C. B!=$: Awhllla: Dept. d C1Wcal Medldn~, Oxlord:
(1) Dr. L. h o n : South Africa: Dept. of Medicine, Untvrnlty of gutmenfCTo1ogy:June $961, forsir month..
Cape Town: blochemi%q: Octobm ,960, for t h x r y c m (nlth (uiil) Dr. A. W. Wawy: Egypr; h t t l&rc.rch b r . , A M m :
nuMtion: June 1 9 6 ~fororeyear.
(U) Mr. T. A. h=: U.K.: D e p , of Phyialogy. A d l a n Nationrl ( u l v ) Dr. P. A. hngley: U.K.: Unlvcnlty Collage sf Rhodah md
Unlvmlv, &h: physiology: October ,960, for two y e n Npmhd:mology: Avgvrt ,962, for thrn y u n .
(with Crpcn~U). (=v) Dr. C. Domlngcr: South Africa: M.R.C. Experinwrrl We
(Ill) Dr. M. 1. h d : A w m l h : School of P+, Loodon: pumY- pathology Reararch Unit, H a m n m l t h : ndlopathology: July ,961.
eology: Onobcr ,960, for one yur. for two yean.
(1") Praf-ror T. Fujiwan: J a p : Dept. 01 Biochunisq Tdniry (~vi) Dr. D. Gaopm: Indla: Dept. of ClInical Mcdiclnc. Oxford:
College, Dublln: b1oehcmi.q: Octobv 1961, for one clinicalmcdicinc: Octobu r961,fortwoyurs.
(v) Mr. 1. W. P h l b : Auafnlia: h . t 0fAnim.l Phpiology, b b n h u n , (~vli) Dr. H. Mddonado: Algmttnc: Dept. of Anrtomj, Univmiy
Cambridge: physiology: October ,960, for two y-
("1) Dr. D. Ratkmlc: Yugoslavia:lrul. of Animal Physiology Babnhun
(with College London: physiology: D e c e m k r96r, krone yru.
( ~ v i l i )DF. A. Watcn: Awfnlh: Dcpr, of Hacmrmlagy. P q d m f s
M c d i d School of London: h.anuology: N o v c m k ,961, for two
Gmbrldge: physiology: & t a b u bcr960,fbcrrtwo~~n W I & Q ~ ) ~
(adx)Y C. B. Rlcharda: U.K.: D e p ~of Patholog)., tmbridgc:
("11) Dr. K. L. S W : Jamdo: Bolton Clry Ho%pltal. U.S.A.: mcdieinc:
Novonbar ,960, fordcvenmonth.. b l o c h d a q : Jrnmry 196.. for two F (wlthaecaw.).
("ill) Mr. C. P. Rmcbandran: Indla: Uverpaol School of Tmplcal (m)Dr. A. R. A b u A&&: Egypl; R m t t RLaursblart.. A b m k n :
Medicine: November 1960, for may-. nucitlon: Dcrcmbcr ,961, for ovomonth..
($1) Dr. H. R. Moudgal: India: St. Mary'r Hapirrl, London: Immune ( n a i ) Mr. E. J. A. L a U.K.: Dcpt. of Hvmvl Anammy, Oxlord: sell
l o g : November ,960, for two yern. physiology: December ,961, forthrecyan.
(X) Dr. A. F. Lever: U.K.: Medical Unlt, St. M q ' s Horpitd Medical ( n a i l ) Dr. G. L. M o n b m : Nlgmh: Dept. of Mcdldnc. U n l d
SFhwl, London: urdlovusdar d i m e : Fcbruary 1961, for thme College of l& b: .
ncurdogy: Dcccmkr 1 9 6 ~ for onelP. ( I
(xi) Dr. D. H. W d t m : U.S.A.: P h y i U I r c h - C h d c h u Inrt., b l c : ( d i ) Mr. A. Pciolflin: U.K.: Inst. of A d m l Phy~iolqgy. h b h ,
blophylu: F c b r u y 1961, forfourmonth.. h b d d g e : immunology: April xp6?,fmonc y u r .
(At) Mr. Chrn Yaw Chcong: Malaya: London School of Hygiene and (-1") Dr. J. R. h-s: Auafnlh: Unlvmlq CdLgc Hmpltrl, Loa-
Tmpical Medldnc: tropical vimlogy: M m h 1961, f o two yam. ~ don: mcdlclne: from D s a n h r 1962. for on= y u r .
(xlli) Dr. M. A. F c m d o : Malaya: Dcpr of h i t o l o g y , Unlvaniry of (m) S. ha,:U.K.: National I m . for R a m & In D.lqing,
Sinppore: prrultology: Much 1968, f o r m y.
(AV) M J. Kirkland: A w f ~ U a : D c p m n m t d Blochcmi.q, Gm.
Shinfield: ~ h n i o l o w :l- ,962. for one, .
m . . . m
Dr. D. Wcir: Eire: Wcrtan Gmcnd Horplt.l, Edinburgh: gutro-
bridge: blachcmlrhy: Much 1961, for one yur. g :
~ ~ 0 ~ 0J d yy1962, foroncyur.
( m i i ) Mr. A. H. Underwood: U.K.: Dcpt. of Blochunlatry. Oxford: Now from To SuhJrn
blochunistry: A u p t 1961, for O ~ v.
Dr.ThmWhla L d Babnhvn
Dr. R. G. M&@ Edlnbvrgh Slackholm
I Trndllng h a r r b Rlbvdlpr:
(a) 51, HUT W~1111mr TravdllngFdlowrh!p eisardedby d Aledim1 n r r u ~ h
Cound (&Io&8r01 oJSr.,ooopr 0nnumj.r 5 ~ e m t ) : (a) Awarded &$re d r 3m Aupn 196oaode&lrtinlo 19642:
x961/6z Dn. D. G. Penington, R. W. R. Ruadl, J. S, ~ l n d d , (1) Dr. I. dc Bvrgh Ddy, F.R.S. (Ualvuriy of Oxfod): plmav.y
R. Hrncock. phydology: tahddurfrtulcculdres&-U: wr84r.
,962163 Dn. M. J. Purvca, C. A. HopWm. C. Kldd, D. A. R. (11) Dr. F. W. Chathwy (Univunly of L e d ) : intcctiam of the h:
Sirnon,. n s w c h u e t u l u : by Mr. J. D. To+ and a p e s : r s n d i .
(b) WcII~omrT r ~ n l l l n ~
Rurorrh fd11111hip~: Indiddual wards; (iU) Dr. R. G. Cochnvlc (London): rvMing u p r m c . of a ''Lpronl
( N m ; roun8y;plorrojlmrk; mhlm; don or prlodoJtenur~) (1") Prokraor E. G. Whltc (Unluurlty of Lkrpool): - l IlthirL:
uriaancc by Mr. P. PorteradMr. R. J. Truchruch: 195s-Sr.
(V) Drt R. R. A. Coomb. ( U n l n d y dCunb11dgc): dgctiguu in &sue
D ~ .
c ~ e : u ~ a f r a u r d t b y A.S.KrIw. 1959-61.
(4) Pmfcsor A. St. G. Hugget,. F.R.S. (St. Mvy'l H a p i t d M &
(Ill) Dr. W. 7. Drabhie: U.K.: Univcnity of Pemaylvanh: mlcro. School): f o c d physlol~gy: t e c h n l d a w l r r m a a n d u p u u a : rsbo.
blology: ,961, For onc ymr. -
for five y
(1") Dr. 1 Hudwlcke: U.K.: CoI~mM~Univcrsity: cllnlul blochembtry: ("11) Slr Rdolph Percrs, F.R.S. (University of Gmbddge): MO-
, s s , , for 0°C yur. eh.mbtry: upcnwr: ,960- .
(ViU) Mr. j G. Mvmy (King's College Hapial. Landon): upcrimcnal
(v) Dr. G. Illcl: Hungay: Uolvenlty College Hoapihl, London:
upedmcnhi pathology: xgbr, for aixmonth. py
, r: p k m c o l o @ daskarcs hyMi.s M. ]m d U m - :
("1) Dr. 1 D. Kohll: India: Unlvenlty of Manitoh, Onad.: phms-
. ,g&-63. -
cology: 1.161, f010ne year. (l*) Dr. G. A. ~ c r h t(udvcnity of Southampton): h o r n s d
("11) Mr. W. R. A. Mune: U.K.: M-hvactm lnrlitutc of Te&ology: Invcnebratcr: research u s h i : tg6c-63.
pbydology: ,961, Lraix monrha. (X) Dr. Angel. T ~ y l o r(Quccn Uiubnh C~llcgc, London): p i t -
(vlll) Or. S. P. S. Tcatia: India: Univtnity College Hospital, London: o l w : t=cMmI uriraarc and uxpxpara: 1 9 6 4 3 .
mchbolicdlruuc~:,961, for fiftcenmontha. (xi) Pmfesaor D. Rowlcy (Unlverziy of Ablddc): m i c m b i o ~ :
(L)Dr. 0. V. Sirek: Cm& Chl-: Mochrmimy: r s s r , for d r u p m u uld cqnipmcnr for Dr. ~ c c v a 'work: 1 9 6 4 1 .
(h) Aaorded h 1960-61:
Trorclllogh r c h Fnllowrhlpr:
(l) Pmfc.sor Dune Kathleen lamUc, F.R.S. (Dcpt. d
Chcm(.try, University Callego Ladon): biophydra:
The cost of these ir shared wlththc O r l s h r g FadundtioninDonnark. u p m u d a p d a l covrsc for Mr. Jrmu Coppola: ,960 616
T o d contdbutlon by the T m t in 1 9 6 ~ 6 wu &3,064.
1 (U) Professor Sir Bryvl Matthew, F.R.S. (Phpiologid
Labonby. Cambddg~): cnd~cri~ology: of p gcoat
Dr. Emil Poulrcn
lunrhdfnafarDr. ComUnc'&wark: 1960 . . LryOo
(111) Mr. P. E. M u d u n d (Unlvenlty d W i w a ~ n n d ,
Dr. A. P. Hayward C I U ~ W Copcnh.gen Electron micrascapy
Dr. S. L. Rowlu Blrmlngham Copmhsgcn Dcnal blochrmlstry
(d) Wdiro-Swdld 7rarhrh11fn~ ~ u r ~ u rF~d l m ~ N p :
h h o
east ~ f p r e p t c w u a n d t h c r u p c m : 1968 . . £fro
(v) Dr. Mwhc Vogt, F.R.S. (A.R.C. h .d A d d t
The rat ofthcse 18 h r c d wlth thcSwcdlahMcdIca1R u m & Council. Phpiology, BBbnhun, Cambridge): phpiology: puu
Total contributioo by the Tnut In 1960-61 W- s384. Ume$er?icca o Mn. L i ~ b a r n ~ f o r e i ~ h t m o ~ I b . :
r l961 £36-
Mr. I. D. Altkm Vcfuioyr m d i - U.K. U.S.A. S.
Mr. B. T Allm
. Blophyd- U.K. U.S.A. T.
Dr. S. G. Mmqulrr Endocrinology Swdm U.K. T. &S.
N a asfie
Dr. P. N. Omplrll BlOEho",huy
Dr. G. A. Cuon Dannfal~gy
Dr. A. F. G.,, PlvmYcology
Dr. A. 0 . 7 . a u r 1 a Dmmlogy
Rol. I. ChC3t.r.
Mr. R. A. ClUt Hawtolaw
Dr. H. J. Cllrhcroe
Dr. A. F. Cobhold
Dr. A. Cohm
Dr. A. S. Cohrn Mclrbolle
Dr. CvDlyn Cobs Biophyrio
Dr. M. J. Colbaumc Tmpid
D. R. P. Cook
m. E. H. Coap" EndocrLnolagy
Dr. C. L. Cope
Dr. E. cotfbl"
D . J. R. Cox
h. M. A. Cnwrord Phyliology
h. C. W. c m . MrdlEine
Dr. G. H. c r c u u
Dr. Sybll C r r d Phyriology
Dr. J. W. &"h Biochem~
Dr. D. J. C. C m A w Physiology
MLu R. D. Currli
D?. J. C. D m c Blochdq
Dr. S. P. M u
Dr. B. a w e Pmultolqy
Dr. J. R. de A n M e Rhrvmtology
Dr. A. G. hb", H b c q 01*dmcc
Dr. F. J. Do Mn!A 0b.tcMu
Dr. E. M. D e u e k . .l ,
Mr. J. T. Dlngle Blorhanlauy
D . G. H. DIxon
Dr. B. T. &"OM" Phplologl,
Dr. l. T. Dmpr
Dr. N. K. Dutu Compurtl"~
Dr. K. D. G. Edwrrd.
Dr. J. D. Eiwn GeMlo
Mr. R. G. Elmllc
Dr. 1 L E m q
Ald N m
Pmrldd Su61- Fmm re M
h c. v.
. Gum- Trawl wJ&h U.S.A.
h. L. A. -0. U.S.A. -,
Dr. T. Holmurn U.K. U.K.. FMsC
h. B. E. Holma U.S.A. .
h W. W. MVlmO' h s t h a l
U.K. U.S.S.R. U.K. U.S.A. T. &S
h.K. C. Hmpm U.K. Swedm Dr. l. N. hk8 Gufm South U.K.. T. &S.
Mr. R. W. Horn* U.K. U.S.A.
h.M. Hrvbvon Clccho-
Dr. E R. H u e h &mutology U.K. M* H=-mlog), Sovth U.S.~. T. &S.
h. P E H v g b d o n
. . Pathology Mcxlco
D,. D. H H u e m chc",l,m
U.K. U.S.A. T.
h. W. T. 1rvi.c U.K. U.S.A.
KmP T. %S.
h. V H. June,
A. J.<0h, U.K. T.
EndoCrLndogy U.K. Swltrcrland .
h. B. J m n
Dr. A. Dmrutolog),
Phvmrrnl~gy U.K. U.S.A. T.
U.K. U.S.A. I.
h. W. F H J-tt U.K. U.S.A. T. &S.
h. P. J o b o n
Mr. T. M. Joy.
h.l. L. K&"
I ~ Y
h . . W .. k
Mc :E ::
Mr. R. A. Kekwiek
Dr. G. Kcm ;3;1-
h. A. S. K.lw U.K. T. k S .
Mr. 1. R. Kenyon hmology
Dr. A. K l p l Frnm
h. l. D KohU
h. M. Km..
h. K. K m j r v l ~
h C. Kupfs ::r'
h. C H lack U.S.A..
Blocbcmi,ey U.S.A. Pmt"gd
Pathology g y U.K. 1 &S.
h. B. R. I w ".
h. S. D. b w l u U.K. M. i
h. K. P. Lcdrri. U.K.
Rof. A. hhnImgg U.S.A.
h. J. I h,,
. U.K. U.K.
h. A. F. Lerrr I d WI
Mr. N. R. Ullg
Dr. C A. Ulv.ll
Mr. M. G. London
D,. l. S. hnmuIr
h.M. S. Lao* U.K.
h. R LovcLcc
h. M. R. Luot
Pmrldd Yeor Nam .p.
Dr. LV. W l h n Ncumloa U.K. U.S.A. T.
Dr. I. H. Woktmmdt Pb~loloa U.K. Alutnll. T. (11) 1961 h H m l d Schnicdm To d l c nm laudtnbat lbdu,
k i v e d g m mkgc h rexud,
h P H. N. W o d
Dr. M. A. W d o u w
U.K. f: h the Dept. d P h d o g y
~ d ~ ~ O tde % "'
Dr. C. A. Wrlght Zoolow U.K. Gambh T. &S.
D . D. A. B. "rmg Phploloa U.K. U.S.A. T. (ill) ,961 Dr. h l p h H. ]ohman ?
Dr. I. M. Yomg
Pm'. E. W*
d la cxpullrion m the A d u
maim d ~ o m s m study
the blmd gmupr of thc AB
Told: LI9,3?4 (1") 1961 Mr. A b Robem , b : bi , ~
E" "L c n 'lDo
@) Block rr0.d G.oo*:
- of la expedition m m d y fbc
. & Nab.
ecology nt L
(1) W d m c Centmwy Cclcbratiom: sympo~lum on the pba. U p & , J m c l961 . troo
(U) ~ ~ ~ ~ % ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ $ $ ~ % b d ~ ~ ; n f ~ ~ ; Toa: Tl.rso
Pmbma, Loadon,luly 196,
(Ill) ,at Intcrnatlod p h a c o l o g l d l M&,' sto&&
Aub~fxg61 . . (S) Gmnu loanrd' the Cos' . I s , ~ , ~ d ~ :
(I*) 8th h t e m t i o m ~~angrc; for M i n o b l o ~ o i , M&$
(v) : s X t Z d i 0 & c i
on . ~ i ~ ~ s it o ~ i h o ~ ; :
j u l p 4 u p t 1961
("1) Mcetlng an the ~locheml& o l ' ~ u r n d
h t g R u c a r c h l m f l N t c London May 1g6r
Bdtirh l ~ i
Blophyriwl soilcly ~ k f on the ~ h y . l i
C h = m l q o f t h c~harpholl~lk., London, Osmbcr ,961
(vill) Confcmncc an thc Clidco-puhologial df
K=pori's Hacmangi-corm, Kunpab, ay 1 ~ 6 ,
(h)U.F.A.W. I n t c r n a f i d Symporium 00 the ~,,~&.mt dl
PlinhMana"dAn1mk Londm July xg6r
(X) 1st lntclllltiond ~ ~ l d & l o l o g i a i I Y I F ~ U O ~
Y" 0dn1.. July ,961
(XI) 3f ~ n e - t i o m ~ congr&
(=U) 5th Inlcrmtiod ~ ' ; u m c d m r l i srdpori& o n ' c r n :
P M U N-chemirq.
~ Aweh, luoc ,962 . . . Told: Y,@O
Dr. A. I. Haddowand To enable a :%Id
Stoker afudcnt ofGlasgow U ~ e r s I ~ y
*Wt the East African V l n u R r
(1) ,960 Pmf=-
Str R o b T o - ~ , c ~ o I ~ ~ ~ u & ~
h fbc am.
1. Xd. d .
rear& I n r u ~ ~ cEnrebbc, for
l. H. Humpkcl To-
a m n m b a of
Awuac (U) U v a p o l M c d l s l hdtudon: rcpatrof b m h p u b h h d
bcEobc~oI85.3: 1956, up t o £ ~ , o o o
d ~ h p i c i a mof ~ d ~ ~ b u r g R "d r
(v) 196, Dr. K. VlcXurmn $mi%_tn(lom
booh of mxdlsl hlrtadul Inter&: rgsn. £500 pr
-m f m five y u n .
(b) Awarded l0 1960-62:
("l) 2962 RorCuor E. G. L.
%: ; "
; mZF ,: dnn.
to add= In &urn.
(0% A ~ - Y 01 ~ ~ d i c l nunl~nlu~ity TO-
M:cost of d o p l n g ' a n d Lphylag thc D&
(ii) S-grmp Ruearch i b o n k P y &bidgc: !:;
b I n ~ h k r n m b c n o f s c i ~ 1 i f i c ~ o d i d : ~ ~ 6 ~ yt*
MEDICAL RESEARCH MUSEUMS AN D LI BRARIES
(I) GrontsJorBuIIdlng o r & A~O~IUUU
(1) h t l t u t c for the History of Medicine, Univalty 01
Vie-: to urist rutoranon m d d c u d ~ p m m tof ths To ply the f m of 1.0 h o c l u u uch y u r , for five ycusfmm
U b m y : 196r,avcrthlrcyur. tsooo Oetobu ,960 . , . . . . . P~o.po
(U) St. Bufho!omcw'l Haviral ~ ~ d l j Landoo;
to bY"d and equip a "WcUmmc Resursh Ubv":
&t coil,., A D&:
f to i.fiude h """ GRANTS F O R RESEARCH I N THE HISTORY OF MEDICINE
"Wdlcamc Rcaureh Llbnry" in the B I O C ~ ~ ~ . "b./../. (bC 3 I I t A u p t 1960 onddllefidveln 1 9 6 6 2 :
+"11ding:r961 . . . . .upto C~G,O.O
Dr. W. H. S.
Dr. W. Pqel
(2) Gramfor the P"..na'e ofB.~.b:
(1) University olOxlonl. ~epartmcnto ~ P ~ ~ o toI ~ ~ Y : Pmfrvor C. Uoyd dsnd
pu&c r c f m c e volurna for the Dcplwcntal Smg.m.Gptain l. L. S.
LlbnPy: r96, &"Iter, D.S.C., R.N.
The W0rrhtpfd S o e l q S a p d for
(U) nay81 ~ o ~ i = g c ~bsictrlciuu i d
of ApoUlrcviu of Lon. M o w (Mr. R. S. Rob-).
London: to hclparock the u b m y ofthc college: N ~ G , ,
£r,ooo p c r m u m f o r s l r y w Mr. A. 2. h b d a P u s 4 m md t for &c
t o ~a,
(111) Unirnaity o f ~ r i t ~ ~h ~ u m bvmcouvcr': to eltabliai stud, of W C madid - p
8 Lib-ay in the new Department for thc Study of the fa thrrcy u n .
HI*v of Mcdlclne md Science: ,961, rsmo p m Dr. R. E. WrigbCSt. subsbtcnce md In hra(gr
u~numforfiv~~~ra . . . , , , CWr dow of h d o l mrtrNl lbDm tbc
MO-, .Lm.w d r a l W . ,
Wm. D a w n and SO" Gc *
- up to r6.o p a m m
(3) Gnroufor YY~NINININI~. nb(odlog, r ~ ~ l ~ gac): n g ,
In p u b l u g aJvsd
* fm up to 6"~
U C u t . - & d Slr Nell
(a) Awmdedk'm In
x 9 6 0 , d U e 5 M f ~ ~ 196- Cloflie, K.C.B..K.B.E.,
(l) Royal Faculty of Phyaiciuu m d S u p o r u . Glupgor: M.C. S. B
,916, 5500 per m u m for five y u n .
(4 ,959 Dr. E. S. C h k e WdImmc Rcsurrh kUowrhlp m d (I") C 0 . 0 ~ ".aurch 0.
~ tmptcrl , m y t l c . .m.
fm *dim et John, Hop&
HcepIop(a1, Wllmmc. U.S.A. for two
(V) D ~ . a ~ ~ ~ i m " " , hkdld'c011;~, ~ & r e : ~ n d ~ L1h'oD
(XI) 1960 PMTcoor C. E. Del- ;%l&g rnd inddmul O L ~ O L P ~h h
w up- of conlin.cd aNdlu of rprvs m d other pmbl-
eoll<Nng nuterlll for -p on &c o*'fi"= y
- . . . . . . . . q*,po
HLtory of Mlcrablalogy.
T d : £333,2,0
Gram awoidrd dudn# 196~-61:
(I) 1 ~ 6 , braor J. 0. k i b o - P - O ~ I p t r o r r o w y - ~ o r O L p ~ s
wlrr of propring a book m &c H i m 9 o j
(11) 1961 Mr. L. G. M11rhrhrhGc-m apdmt 1 0 s & publhhhg a
hirtmy of p b m q in CreatBrlrrlo.
(111) 1961 r
D . K. E. Dcwhunt Pcnolvl grrnt and OL~CNCN f0101k LL
. bard on lbcLwrlrcc w i n
thc Bodkin Ubmy.
(1") z96l Mr. R o b e W. Sbplm W~llcomcR -& RllomhlP m rntyd~
tbc I L and work of Jvna Cwric
(V) 1961 Dr. H. J. b h b Wclleomc R& - kllowrhlp to w t c
(vl) ,962 Edinburgh Unlvurlry Guuuurc up ro cloo *@m 1 in
Rul rs.publbhing Cbadwlck'8 o the
Sadtop o d i d d g ths h.burmn#
P.p"l0"on 'fGrra*,M", 18,I.
(vU) 1961 D . R. R. TRII. C.B.E. Purornlgrmt to workon aDldodldly./
&iclrh Mrdl111 Ble#mphj.
(vU1) 1962 h l. D. Allm Gray
. Canwibution to& thc cou of
publhhing a f i i q .f ths k u d
( . ,962 Dr. F. G u m
L) h i o r Wdlcmnc R a a r c h k l l ~ w h i p
and u p n u a 0"- &c p ty ",ark
on a catdopc of &c m m Collecttoo
of Amrri-at lhc W ~ l I m m ~tlttltrbl
fidlrrl l l b q .
(X) ,962 Dr. A. C. W l l c Purornl p t to wmk on &= Smmm
Age' Gllcmon of rbc Wcllcmc
H h t o r i d McdiolMuwun.
EXPENDITURE D U R I N G 1960-62
O N L O N G - T E R M ARRANGEMENTS
(1) Wdlcome Historiol Medical Mur=wn m d Ubr.ry: m i n g
uperrus, rrhun(rhlngl.ndp& of G ~ ~ m C o l l o rryo,g28
(11) Dr. Huuy Foy md Dr. A f h m Kondi: i l x l a and m&
(lii) = R&
; ~ d ~ ~ ~ EL's'7B9
cO&cll: ' ~ d m i n t h l d , unl; d
W a t A h i u : ~ t a u n c c o f U d f o ~ e ~ t ~. U p t ~ t15,000
LIST OF COMPLETED BUILDING AND
m wbg.,) to
E22 . .
(=it) Gmcmmmt of Kmp: G ~ t r u c d o n of
1Ntlt"fC for RI& on Fmwnd-Mmth
DLme, Ndmbl . . . . .
(mill) Univcnity oEGlugow: Gnrtruedon adSm.ll
A d d s EXpaLocnbl R u m & Unit W
Shorc Hmplbl ofSydney, N.S.W.: Caurruc-
tlon of "Wcllcomc LabonDriu of Fxpcri-
m m h l Medicine a d S q q "
( a ) Unlrcnity of Edlnburgh: Exanrlon of re-
lurch accwmodrtlon for Dcpsrmrmt of
cu1) .i E*mrion1
r u d .ecommodadan for Dcpurmmt d
( d i ) j? g&
kH! &lai D&ir oi
Medldnc, w d m o r r : b b o n t o r r for d"of
(a111)"6.~~d$~%m"H"H"H~bI, i r n i k :
u t a u l o n toclinical -mh block . .
( a i v ) Univmity of Leeds: Laboratode. for the
Depurment of M c d l d Phyrlcr and for
w'"g . . . . . . . Umlogy . . . .. . .
(L) Unlvcraity College London: Extaaim of Unkcrsity of Oflord: Animal h o u c for the
m& rccommodatioo for Dcmment of
Evgmic~ . . . ,' . .
. . . .
Dcplmncnr of M d c l n c
Unlversb of h b d d e c : bboraforiu for h=
(X) St. Thomu'a Horplbl, Landon: To u t c n d
rccommodation far r r r u ~ c h watmtmtmt
-=er by Irndladan in hlgh'.P~ure a m
(X!) I N ~ I u ~ ECancer Rcrureh. Unirenity of
R u u x h UnirbJam.lca . . .
St. MYy" Holpibl, London: Anlmd m m -
London: Comtructlon of "Wclicomc b b o r modatlm far the Medlul School bborpforfa
awry of Pharmacology m d EXperimcnbl
Chmothenpy" . . , . .
(X!!) Pmtgndlutc Medical Schwl d Landan: Pm.
mrt d bbonitoriu for Exacrimmtd Re.
$m&in Surgery . . . ' ,
(=IN) University of St. Andrcm: Gamy ~ u i n e
Laboratory ("Wcllcomc Labantoriu of
Phrmucology") . . . . ,
(=I") W m t t y of Edinburgh: Imtitntc of A n i d
Gencda: Rebuilding of brccdlng hovra for
mice m d rabbi". . . . .
(m) Unlvcnlty of Edlnburgh: Prmldan d r
R c v h t y DLwre, Rer-mh Unit
for an eswy o r a report on an original research dealing with milihl,
rg6r G p i n Austin D. Potcnm, Medical Carp, U.S. Army, for his -.ay SOME RECENT PUBLICATIONS
;;;:;",n;lDci?ic&nb"'~n 01 hmling procure, in wnlne flexor
Gptlin l l q c r l i . iilller, hl~dirillCorps U.S. Nay..far his eruyenritlcd:
OF THE WELLCOME TRUST
'Dronningml nix Portimmcrjlon S!ndrams'. A Catalogue oE Printed Books in the Wellcome
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111. R O Y A L A F R I C A N S O C I E T Y printed before 1641. With a ~ O I ~ W Oby Sir
W ~ ~ r c o u r r n ~ l sron
hl D E ~ X G U ~ H E S ~ n v l c r rTO
D Amrc~ Henry Hallet Dale, O.M., G.B.E., M.D.,
Innirard iy Slr Htnr). IV~Iiiomrin rglo F.R.C.P., F.R.S. pp. xvi, 407. 1962. Price
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............................ ;y;:;o;:;;:; and Science in the Wellcome Historical Medical
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Socier)., tllc R q s l Comrnan\redrh Society and thc: Intemationd
African Institute. Manuscripts. Volume l. Manuscripts written
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indexes. Priu net Sro. ~ o s . ,postage paid.
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lnnirvrrd h j Sir Ikny li"iI1~omr
in ,931 life with a bi%lidgraphy of his writings. By
Geofiey Keynes, Kt., M.A., M.D., D.Litt.,
LLD., F.R.C.P., F.R.C.S., F.R.C.O.G. 17
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t h c Royal Cummon~rcalthS o c i ~ t ym d the i(oyal African Society.
W. Bonser. pp. 450. 1963. Pricenet Sz. ros.,
1960 I'rofcssoi I'llilip Mryrr: 'Urbsniwtion in a divided rosicty.' postage paid.
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