Medical Student Research Forum

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• Research in Medical School
• Abstracts and the Medical Student Research
• Year-long Programs
• MD, with Distinction in Research
• MD-Masters in Clinical Science Program
• Calendar
• Grants Primer
 What Steps Does Medical Training Entail
and What Role Does (Can) Research Play?

  • Medical School **
  • Internship
  • Residency
  • Fellowship **
  • Faculty **
          Research in Medical School

• Easiest to conduct before year 1 and / or between
  years 1 and 2
• It is also possible to conduct research as an elective
  during the 3rd and 4th years
• Some students elect to take a year off to obtain more
  detailed research training
   –   Sarnoff
   –   Doris Duke
   –   Howard Hughes Medical Institute
   –   NIH-HHMI
   –   Other (e.g. CDC, Fulbright, many programs in different
Research in Medical School

     Research in Medical School:
         Altruistic Answers
• To advance the state of medical knowledge
  and practice
• To cure disease and alleviate suffering
      Research in Medical School:
          Realistic Answers
• Because it is interesting
• For recognition
• To explore areas that may potentially be of long-
  term interest
   – Clinical area
   – Research area
• To develop useful contacts
• To cover all my bases
   – Maybe I might be interested in research as a component
     of my career…..
     How Much Difference Can It Make?
• Competitive residencies and fellowships
   – Orthopedics, Neurosurgery, Ophthalmology …. but really all.

• “The panelists, led by Dr. Paul Klotman, chief of medicine at Mount
  Sinai School of Medicine, then detailed the steps medical students
  must take to achieve a successful academic career, such as deciding a
  course early on: engaging in scholarly pursuits during residency
  training, choosing a mentor, finding a supportive institution for
  research, and the process of applying for grants in the postdoctoral
  years. Dr. Klotman congratulated the Doris Duke fellows for having
  the wisdom to take a year out of their medical school training to
  obtain formal training in research. He averred that commitment is
  one of the leading qualities that fellowship directors look for among
  their applicants and that participation in a fellowship such as the
  Doris Duke Clinical Research Fellowship demonstrates a sincere
  interest in a career in academic medicine.”
                                   Journal of Investigative Medicine 51: 330-340, 2003
    What is Available?
• Programs
• Activities
• Advice
  Summer Medical Research Programs
• There exist a variety of targeted programs (here and at
  other institutions) to promote research among medical
  students: bulletin boards near student mailboxes and
  outside J6.110
• At UT Southwestern, opportunities are available in
  almost any area: identifying a mentor and the definition
  of a project are all that are required
• This past summer, more than 130 students participated

• Students are encouraged to work within formal
  programs - whether on or off campus; whether a part of
  summer (or year-long) programs
   – Running list maintained as link off of the Medical Student
     Research page
Medical Student Research Forum
• January 16, 2007
• Guest speaker: Joan Schiller, MD
• Abstract forms available & to be submitted on line
• Abstract deadline: 5 PM on November 13, 2006
• Panel of judges will select the top abstracts: oral
  session presentations
• All students submitting abstracts are eligible to
  participate in the poster session/reception
• Prizes will be awarded for top oral and poster
• Everyone is invited to submit
• Success of your project is not a prerequisite
   – Exposure to faculty and fellows that share your interests
   – Efforts in science are not always successful
   – Presentation is an essential element of science
      • Conception  Execution  Reporting
• The abstract book is published
• Participation and publication should be listed on your
                   Year-long Programs
• Doris Duke Clinical Research Fellowships
   – 2006-2007: John Anderson, Christopher De Renzo, Shana Elman,
   Allison Jordan, Justin Leitenberger, Christopher Maroules, Monica Mead,
     Sarah Davis
• HHMI Research Fellowships
   – 2005-2006: Sophie Esmail
• ‘Cloisters’ (NIH-HHMI Research Fellowships)
• Sarnoff Research Fellowships
   – 2003-2004: Neil Patel
• Fulbright Scholar
   – Vuong Nguyen - Global AIDS Program (Kenya); 2003-2004
   – Osamah Saeedi - Congenital Cardiovascular Malformations 2005-2006

• Stipend + Educational expenses; more importantly for those that
  have an interest in research, these programs are ‘Golden
  M.D., with Distinction in Research
I. Purpose: To recognize students that distinguish
   themselves in the conduct of meaningful clinical or
   basic research activities during the course of their
   medical school training.

• II. Outcome: Individuals satisfying the program
  requirements would be recognized at graduation and
  on their diploma as graduating with:
                   the degree of
                Doctor of Medicine,
            with Distinction in Research
 M.D., with Distinction in Research

•Research may be in the area of clinical or basic
research and should encompass a minimum of 16
•Research successfully performed toward attainment of
a Ph.D. would not be eligible for this program.
•Research performed under the auspices of a nationally
recognized research program (e.g. Sarnoff, Cloisters,
HHMI, or Doris Duke Clinical Research programs)
during medical school will be eligible for fulfillment of
the research requirement.
M.D., with Distinction in Research



MD-Masters in Clinical Science Program

 • In order to provide a more robust opportunity by
   which interested medical students can enhance the
   level of clinical research training, UT Southwestern
   has established a combined MD-Masters in Clinical
   Science Program.

 • This training program will combine rigorous didactic
   training with a mentored clinical research project.
   The completion of the didactic and practical training
   will be marked by the successful submission and
   public defense of a Masters thesis.
 MD-Masters in Clinical Science
Who is eligible ?

• At present, this program is available only to medical
  students enrolled at UT Southwestern. It is
  anticipated that this program will become more
  broadly accessible in future years.
  MD-Masters in Clinical Science
What is the timing of the program?

• It is anticipated that interested students will conduct
  the two years of the Masters program following the
  completion of their third year of medical school. In
  selected instances, applications will be accepted
  from students that will have completed their second
  year of medical school.
     MD-Masters in Clinical Science
What does the program provide?
• Following the third year of medical school, students enter
  the two Master's years of the program. During this time,
  students will receive a stipend, graduate school tuition,
  and health insurance. This support will be continued
  throughout the duration of the Masters years of the
  Importantly, after the successful completion of the
  Master's component of the program, students will receive
  stipend, medical school tuition, and health insurance
  support during their final year of medical school.
     MD-Masters in Clinical Science
Application process and selection criteria

• Application to the program will employ the electronic graduate
  school application. Successful candidates will be chosen
  following review by the MD-Master's Program - Selection

• In addition to the completed on-line application form, an official
  medical school transcript and two letters of recommendation are
  required. For students applying for the 2007-2008 school year,
  applications should be completed by January 15, 2007. Students
  selected to participate in the program for the 2007-2008 school
  year will begin their didactic coursework during the 2007 Fall
      Research and Medicine Seminars

• Experimental approach to bringing into focus the impact
  of research on the practice of medicine
• Case-based approach presenting data by which the
  information derived from the understanding of a disease
  at a molecular level has been harnessed to derive
  important new avenues of treatment
   – Noon time, usually D1.600 or D1.700
• Success is attainable in every venue; background is
  no impediment
• Build on your strengths and interests
   – Materials engineering  apply to medical biomaterials
• Associate with a good mentor / group - - and stick
  with it; become more than a name on a page
   – Small investment over long time = big return (e.g. group
     meeting or research conferences)
• Identify a scientific ‘400 lb. Gorilla’ to help you to
  open doors
• Be efficient with your time; it is difficult to move
  ahead if you are always starting over
• Think ahead and plan - do not procrastinate
                 Calendar of Events
• Summer Research: now – August 4
• Research Interest meeting: Late September (venue not yet set)
   – Year-long programs & visitors from the different programs
   – MSRF planning
• MSRF abstracts due: November 13, 2006
   – Judging and selection for oral session usually completed ~
• Application deadlines for the year-long programs are variable
  (generally in early January)
• MSRF: January 16, 2007

• Research and Medicine Seminar Series: variable
   – Held at approximately monthly, scheduled around the minefields that
     are the MS1 and MS2 curricula; D classrooms, noon, lunch - - RSVP!

• Research in Medical School
• Abstracts and the Medical Student Research
• Year-long Programs
• MD, with Distinction in Research
• MD-Masters in Clinical Science Program
• Calendar
• Grants Primer
Duke ….
                                   K Awards


   Nine (9) different Career Development Awards for individuals with a health
   professional doctoral to consider. Most support individuals after they have
   completed clinical training and have accepted a faculty position.
• K12 - Mentored Clinical Scientist Developmental Program Award -
  Institutional Award for the development of independent clinical scientists. Dr.
  Milton Packer is the UTSW PI for this program that supports 14 clinical
  research scholars in patient-oriented research. Scholars commit 75% of their
  time in a 3-yr educational and training program to prepare for a career as an
  independent clinical investigator.
• K07 - Academic Career Development Award - Developmental/Leadership in
  academic instruction, research, administration. 2-5 years, 25-75% effort,
  requires institutional sponsorship.
• K08 - Mentored Clinical Scientist Development Award – Development of the
  independent clinical research scientist. 3-5 years; 75% effort.
• K18 - Career Enhancement Award in Stem Cell Research – Supports full-time
  or part-time training in the use of human or animal embryonic, adult, or cord
  blood stem cells. Usually 6 months to 1 year (up to 2 years) full or part-time.
  (NIDDK, NIAAA, NIAID, NHLBI, and NINR participate.)

• K23 - Mentored Patient-Oriented Research Career Development Award -
  Supports career development for the independent research scientist in the
  clinical arena. 3- 5 yrs; 75% commitment.
• K24 - Mid-Career Investigator in Patient-Oriented Research Award –
  Development of clinical mentors conducting funded research. 3-5 yrs; 25 to
  50% effort.
• K25 - Mentored Quantitative Research Career Development Award – To
  foster interdisciplinary collaboration in biomedical research by supporting
  career development experiences for scientists with quantitative or engineering
  backgrounds. 3-5 yrs; 75% effort.
• K26 - Mid-Career Investigator Award in Mouse Pathobiology Research –
  Provides support for established pathobiologists who wish to devote up to
  50% effort to research and mentoring in the field of mouse pathobiology. 3-5
  yrs; renewable, 25 to 50% effort.
• K99/R00 - NIH Pathway to Independence (PI) Award – (PA 06-133)
  Designed to facilitate receiving an R01 award earlier in an investigator’s
  research career. Provides up to 5 years of support in two phases: The initial
  phase of this project will provide 1-2 yrs of mentored support for highly
  promising, post-doctoral research scientists, followed by up to 3 yrs of
  independent support contingent upon securing an independent research
  position. Award recipients will be expected to compete successfully for
  independent R01 support during the award period. ($90,000 per year for
  mentored phase; $249,000 per year for the independent investigator phase)
Duke ….
                  Medical Student Research Page

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