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					Skills Review
#5 and #6
Skills Review
 •   #5 and #6


 1.   Name the first level of protein folding.
 2.   Name the second level of protein folding.
 3.   Name the third level of protein folding.
 4.   Name the fourth level of protein folding.
 5.   Give an example of the first level of protein
      structure.
 6.   What kind of bonds exist in the first level?
Skills Review
 •   #5 and #6


 1.   Give an example of the second level of protein
      folding.
 2.   What kinds of bond(s) exist in the second level?
 3.   Give an example of the third level of protein
      folding.
 4.   What kinds of bond(s) exist in the third level?
 5.   Give an example of the fourth level of protein
      folding.
 6.   What kinds of bond(s) exist in the fourth level?
Skills Review
 •   #5 and #6


 1.   Name a function of proteins.
 2.   Name a second function of proteins.
 3.   Name a third function of proteins.
 4.   Name a fourth function of proteins.
Mutation
  Pages 307-308




                  By PresenterMedia.com
•Mutations


•   Some are positive
•   Some are negative
•   Some have no effect
     •   Amino acids have multiple codons
•   Pick a number 1-10…
•   Mutagen= Chemical or physical agent that causes a
    mutation
•   ?
•Mutagens
•   Chemical or physical agent


1.   Chemical agents
     •   Benzene, formaldehyde
     •   Plant alkaloids-corn lily
     •   Smoke
     •   Pollutants
2.   Physical agents
     •   Xrays
           •   Buster Brown Shoes
     •   UV Light
     •   Radiation
•Harmful effects of mutation



  1. Cancer



  2. Sickle cell
•Beneficial effects
 Beneficial to whom?


 1.   Resistance to pesticides
         •   Bed bugs
 2.   Resistance to antibiotics
         •   MRSA, VISA, VRSA
 3.   Plant and animal breeders
         •   Polyploidy
         •   Plants are larger and stronger




                                   Triploid watermelons are sterile!
•Mutations
•   2 different types of mutations


1.   Gene mutations
     •   Changes at the base level




2.   Chromosomal mutations
     •   Changes in the number or
         structure of chromosomes
 •Gene Mutations


1. Point mutation
   •   Substitution
        •   Changes in a single gene
        •   CTC glutamic acid hydrophilic
        •   A is substituted for T
        •   CAC valine hydrophobic
        •   Causes sickle cell disease
   •   The fat man ate the hot bbq
       rib.
   •   The fit man ate the hot bbq
       rib.
•Gene mutations
 Frame shift mutations


2. Insertion                     3. Deletion
     • The fat man ate the hot       • The fat man ate the hot
       bbq rib.                        bbq rib.
     • The fat ema nat eth eho       • The ftm ana tet heh otb
       tbb qri b.                      bqr ib.
•Chromosomal mutations
•Changes in the number or structure of chromosomes
1. Deletion
    •   ACDEF
2. Duplication
    •   ABBCDEF
3. Inversion
    •   AEDCBF
4. Translocation
    •   ABCJKL
    •Gene Therapy
    Good or Evil?

•   Gene Therapy
                    •   Cystic Fibrosis

				
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posted:10/14/2011
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