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Interactive Lecture Quiz #3 on
Endocrine Chart, syllabus pages 39-44,
gland, hormone, regulation of secretion, chemical structure
Spring, 2008
By Patricia L. Mansfield, Ph.D.
Directions. Take this quiz using your powerpoint viewer to test yourself and to get immediate
feedback on your answer choice.
I obtained some animations or videos from internet classes or from your textbook author to
demonstrate the important principles covered in this quiz. Unfortunately, I don’t always
remember the website address of the figure; and some websites are no longer available.
3/6/2008
1
1. Which hormone directly stimulates the release of cortisol, a
glucocorticoid?
a. ACTH b. CRH c. aldosterone d. glucagon
2. Which gland secretes cortisol?
a. hypothalamus b. posterior pituitary c. kidneys
d. adrenal cortex e. adrenal medulla
CAPSULE
--------------------
Z.G.
--------------------
Z.F.
--------------------
Z.R.
--------------------
MEDULLA
3. Which hormone or condition stimulates the release of hGH?
a. GHRH b. ↑[glucose]blood c. ↑ lactic acid production
d. TSH e. somatostatin
Another fact to record
on your LIVER PAGE,
syllabus p.120
hGH can only act on tissues
by stimulating the liver to
produce the IGFs aka
insulin-like growth factors
aka somatomedins!
4. Give the chemical structure of hGH.
a. steroid b. catecholamine c. peptide d. eicosanoid
http://en.wikipedia.org/wiki/Growth_hormone
“Growth hormone (GH) is a hormone that stimulates growth and cell
reproduction in humans and other animals. It is a 191-amino acid, single chain
polypeptide hormone which is synthesized, stored, and secreted by the
somatotroph cells within the lateral wings of the anterior pituitary gland. The
hormone is also known as somatotrophin when referring to growth hormone
produced by recombinant DNA technology, and is abbreviated "rhGH".”
From http://www.antiagingresearch.com/
5. Which hormone(s) is (are) secreted by the thyroid gland?
a. T3 b. T4 c. calcitonin d. all of these e. none of these
6. Which of the hormones in #5 is an iodine-containing
amino acid?
a. T3 b. T4 c. calcitonin d. all of these e. T3 and T4
7. Which hormone is stimulated by PTH?
a. calcitriol b. leptin c. gastrin d. two of these
Please add the parathyroid gland to the Endocrine Chart, syllabus p.40. It got cut off by mistake.
PARATHYROID PTH Peptide Bone, Kidney, Increases blood calicum levels by
GLAND Stim. by decreased Small intestine stimulating bone resorption,
blood calcium increasing absorption, and
levels decreasing calcium excretion
8. Melatonin is a ________.
a. peptide b. amine c. steroid d. prostaglandin
9. What inhibits the secretion of melatonin?
a. light b. food c. water d. ↑oxygen
The pineal gland is part of the
diencephalon.
10. Based upon the correct answer in #9, which sensory
organ must communicate with the pineal gland?
a. eye b. ear c. nose d. muscle spindle e. skin
I thought you might be interested in this!
The visual pathways from the eye –axons from the optic
tract– send axon collaterals to synapse in a hypothalamic
nucleus called the suprachiasmatic nucleus (SCM). Axons
from the SCM synapse in the pineal gland.
11. What event stops the secretion of insulin?
a. eating b. glucose levels return to normal c. hunger
12. How would you describe the relationship between the
hormones, glucagon and insulin?
a. antagonistic b. additive
c. no relationship: secreted by different endocrine glands
d. dependent: one stimulates the secretion of the other
Answers
1. A
2. D
3. A
4. C
5. D
6. E
7. A
8. B
9. A
10. A
11. B
12. A
RELATIONSHIP BETWEEN
Chemical Structure of Signal Molecule – Signal
Molecule Behavior at Target – Signaling Pathway
•Peptides, Amines, Steroids
•Pull out your SIGNALING PATHWAYS handout
as you review the next slides.
Review the major facts about the
different classes of hormones
Signaling Pathway for Peptides:
Peptide Hormone-Receptor Complex
• Hormone binds to cell surface receptor– can’t enter
cell, so they need signal amplification and a second
messenger
• Enzyme activation •http://highered.mcgraw-
hill.com/sites/0072437316/stud
• Second messenger ent_view0/chapter7/animations.
html#
• Cascade of events
• Open channels
• Cellular response
Peptide Hormone-Receptor Complex
Membrane receptors and signal transduction for peptide hormones
Figure 7-5
Steroid Hormones: Features
• Cholesterol-derived
– Lipophilic and can enter target cell by simple diffusion
• Cytoplasmic or nuclear receptors – Don’t need
signal amplification and a second messenger
• Activate DNA for protein synthesis
• Slower acting, longer half-life
• Examples
– Cortisol, estrogen, and testosterone
Amines
•Catecholamines: Epinephrine, Norepinephrine
•Second messengers– cAMP and Ca++
•Use with your handout
http://highered.mcgraw-
hill.com/sites/0072437316/student_view0/chapter7/animations.html#
Steroid Hormones: Structure
Steroid hormones are derived from cholesterol
•Mechanism of Steroid
Hormone Action at
http://highered.mcgraw-
hill.com/sites/0072437316/stud
ent_view0/chapter47/animation
s.html#
Figure 7-6
Thyroid hormones– T3 and T4
•Lipophilic hormones
•Mechanism of Thyroxine Action at
http://highered.mcgraw-
hill.com/sites/0072437316/student_
view0/chapter47/animations.html#
Silverthorn, Figure 23-9: Thyroid hormone synthesis
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