0415855.19991026.3312 by msds


									Safety Data Sheet

Choline chloride

1. Product and Company Identification
Product name Product code Company information Choline chloride 04 1585 5 Enquiries: F. Hoffmann-La Roche AG Postfach CH-4070 Basel Switzerland Phone Fax *41-61/688 54 80 *41-61/681 72 76 Local representation:

2. Composition/Information on ingredients
Chemical name Synonyms CAS number EINECS number Roche number Empirical formula Molecular mass - 2-Hydroxy-N,N,N-trimethyl-ethanaminium chloride - (2-Hydroxyethyl)trimethylammonium chloride 67-48-1 200 655 4 Ro 01-0587/000 C5H14ClNO 139.62 g/mol
OH N+ Cl -

3. Hazards identification
Most important hazards - No particular hazards known.

4. First-aid measures
Eye contact - rinse immediately with tap water for 10 minutes - open eyelids forcibly - consult physician - remove immediately contaminated clothes, wash affected skin with water and soap - do not use any solvents

Skin contact

Date: 26.10.99/CSE (SEISMO)

Replacing edition of: --

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Choline chloride

5. Fire-fighting measures
Suitable extinguishing media Specific hazards - water spray jet, dry powder, foam, carbon dioxide - consider dust explosion hazard - formation of toxic and corrosive combustion gases (nitrous oxide, hydrogen chloride) possible

6. Accidental release measures
Methods for cleaning up - take up mechanically and dispose of

7. Handling and storage

Storage Storage conditions - cool and dry - keep container tightly closed

8. Exposure controls/Personal protection

Engineering Measures Personal protective equipment Respiratory protection Hand protection Eye protection

- see 7.

- in case of open handling or accidental release: particle mask or respirator with independent air supply - protective gloves - safety glasses

9. Physical and chemical properties
Colour Form Odour Bulk density Solubility colourless crystalline powder slightly aminelike 800 kg/m3 1’000 g/l, water (20 °C) completely soluble, methanol completely soluble, ethanol badly soluble, chloroform badly soluble, benzene 6 (10 g/l) 303 to 305 °C (with decomposition)

pH value Melting temperature

Date: 26.10.99/CSE (SEISMO)

Replacing edition of: --

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10. Stability and reactivity
Conditions to avoid Note - humidity - temperatures above 180 °C (decomposition with pressure increase) - hygroscopic

11. Toxicological information
Acute toxicity LD50 LD50 LD50 LD50 3’400 3’900 53 450 mg/kg mg/kg mg/kg mg/kg (oral, rat) (oral, mouse) (i.v., mouse) (i.p., rat)


acute effects following excessive dose: convulsions, excitement food additive foodstuff, harmless at normal use lowest estimated lethal dose (oral): 200 to 400 g oral doses of 10 g do not have any negative effects in human beings

12. Ecological information
Ecotoxicity Air pollution - fish, unspecified LC50 (96 h) > 1000 mg/l - observe local/national regulations

13. Disposal considerations
Waste from residues - observe local/national regulations regarding waste disposal - large amounts: incinerate in qualified installation with flue gas scrubbing

14. Transport information
Note - not classified by transport regulations

15. Regulatory information
Note Toxicity class (Switzerland) Water hazard class (Germany) - no classification and labelling according to EU 5 1: weakly hazardous for water (according to annex 1 or 2 of directive VwVwS of 17.05.1999)

Date: 26.10.99/CSE (SEISMO)

Replacing edition of: --

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Choline chloride

16. Other information
Use Safety-lab number Edition documentation - food additive - BS-5725 - first edition

The information in this safety data sheet is based on current scientific knowledge. It should not be taken as expressing or implying any warranty concerning product characteristics.
Date: 26.10.99/CSE (SEISMO) Replacing edition of: -Page: 4/4

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