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Optimum Filtration Solutions for OEM Manufacturers Unprecedented Performance and Choice Optimum Filtration Solutions for OEM Manufacturers For companies who use filtration devices as a critical part of their equipment, Whatman offers filtration solutions across a wide assortment of technical specifications — including choices in configurations, pore sizes, flow rates, housing sizes, connectors and adapters. Gain a competitive advantage with Whatman products, whether you develop devices or improve existing devices. The flexibility, filtration performance and quality Whatman delivers will suit your most exacting specifications. A HISTORY OF EXCELLENCE In 1740, Whatman was founded as a supplier of premier custom paper to world leaders. Our technologies and expertize have evolved over the centuries, but our passion for quality products and unparalleled customer service remain unwavering. Today, Whatman is a global leader in separations technology, and our products are universally accepted by the major scientific and industrial concerns of the developed world. Our in-depth understanding of the filtration industry enables us to build long-term relationships with customers who see us as filtration partners, equally committed to innovation and quality. Whatman consultants work with OEMs to assess their unique competitive situations, customer requirements and business dynamics before providing the optimum filtration solution. Table of Contents SECTION PAGE Membrane and Media Options [ 4 – 5] Disk Filters [6–9] A COMMITMENT TO QUALITY All Whatman filters are manufactured according to our strict quality assurance program. Whatman multiple manufacturing sites have implemented quality systems designed to meet the rigorous requirements of ISO-9001 Standards at a minimum. It is our goal to provide our customers with the highest quality products in the industry. Capsule Filters [10–13] Specialty Products [ 14 – 1 5 ] Customization Options [ 16] Filtration Basics and Design Considerations [ 17] [3] F I LT R AT I O N S O L U T I O N S — U N P R E C E D E N T E D P E R F O R M A N C E A N D C H O I C E MEMBRANE AND MEDIA OPTIONS An exceptionally wide selection of filter media is offered to our customers for incorporation into their devices. Membranes such as PES, nylon, PTFE, PVDF, PP and track-etched polycarbonate and polyester are available. Whatman also manufacturers other unique filtration medias such as cellulose paper, regenerated cellulose membrane, nitrocellulose membrane, cellulose acetate membrane, mixed cellulose ester membrane and Anopore® ceramic membrane. Meltblown polypropylene and glass microfiber filters offer versatility with high flow and high particulate loading. Precision woven screens are also available for coarse particulate removal. Choose your filter material from our extensive range of media options from leading manufacturers around the world, including Whatman manufactured filtration materials. Glass Microfiber (GMF) High bacteriological efficiency filter with excellent flow rates; very effective prefilter GMF has exceptional filtration characteristics. Structures produced from GMF combine high bacteriological efficiency (typically 99.999%) with low resistance to air flow and high particle loading capacity. This media is available in a range of filtration efficiencies including HEPA (which retains 99.97% of particles > 0.3 µm) and ULPA (which retains 99.9% of particles > 0.1 µm). GMF can be treated to make it hydrophobic or oleophobic. Non-Woven Polypropylene (NWPP) Ideal for heavy duty fine filtration Meltblown polypropylene is known for its durability and high dirt holding capacity. It has extremely high permeability for a given retention and is very versatile. Polypropylene is essentially inert and resistant to many chemicals, even at elevated temperatures. These properties make it suitable for the filtration of most liquids. Polytetraflouroethylene (PTFE) Hydrophobic microporous expanded PTFE membrane. Aggressive chemical and air/gas stream filtration PTFE is the most inherently hydrophobic microporous membrane available today. This durable media has a wide operating temperature range and resistance to the destructive effects of many chemicals. This media is widely used in venting applications. Woven Media/ Screen Precise coarse particulate removal Polyester and polypropylene screens are available. Woven media/screen provides a long service life and high resistance to physical and/or chemical damage. Precise mesh openings make this media an ideal filter for coarse particulate removal from blood or ink. Woven media/screen is extremely clean and non-shedding. Polyethersulfone (PES) Aqueous solution filtration for pharmaceutical and biological applications PES has very low protein binding characteristics, high liquid flow rates and throughput (long life) and low extractables. Polyethersulfone’s hydrophilic characteristics allow it to be used with both liquids and dry gases, making it suitable for a variety of environments. PES will withstand autoclaving. PES is the membrane of choice for many clinical applications. [4] F I LT R AT I O N S O L U T I O N S — U N P R E C E D E N T E D P E R F O R M A N C E A N D C H O I C E Nylon Aqueous solution filtration A naturally hydrophilic membrane with low extractables, low protein binding characteristics, and wide chemical compatibility, nylon is often used for sterilizing and clarifying liquids. Positively charged nylon membranes enhance the retention of fine particles such as bacteria and endotoxin, making them a common choice for medical and pharmaceutical filtration applications. Polypropylene Membrane (PP) Ideal for aggressive filtration applications A membrane which is resistant to a broad range of chemicals even at high temperatures. Low in biomolecule binding. Adaptable material for applications ranging from air to liquid filtration. WHATMAN SPECIALIZED MEDICAL MEDIA Whatman has been a supplier of medical device filter media to leading healthcare manufacturers for over thirty years. Today, our filter experts are ready to work with your company to provide filter media that meet your unique requirements. CAPABILITIES: • Manufacture of high quality cellulose and glass microfiber filter media which can be incorporated into OEM devices • Development of specially treated materials to impart hydrophobicity, strength and/or oleophobicity • Provide configurations to Track-etched Membrane (TEM) Surface capture membrane with very precise pore size Track-etched polyester and polycarbonate membranes are surface capture filters with very precise pore sizes. Tracketched membranes are manufactured by Whatman from polyester and polycarbonate films. The technology produces membranes with accurately controlled pore diameter and pore density, which capture particles on the surface. Membranes are available in a range of pore sizes down to 0.1 µm. Polyvinylidene Fluoride (PVDF) Useful for a wide range of liquid filtration applications PVDF membranes are naturally hydrophobic but are modified to a hydrophilic nature. Useful for a wide range of applications, both aqueous and non-aggressive solvent-based. It is typically low protein binding and used frequently for sterilizing filtration. meet your needs, from reels and sheets to die cuts PRODUCTS: • Hydrophobic glass filter media for respiratory therapy and CO2 filtration in minimally invasive surgery • Filter media for venting applications • Cellulose based media for heat or moisture exchangers and humidifiers available in flat and corrugated reels [5] F I LT R AT I O N S O L U T I O N S — U N P R E C E D E N T E D P E R F O R M A N C E A N D C H O I C E Disk Filters F I LT E R H O U S I N G S Whatman offers a comprehensive line of disk filters for small to medium volume filtration. Filter diameters range from 4 mm to 60 mm and filter housings range from polypropylene to polycarbonate. Choose the filter that best suits the needs of your application. Select 4 mm, 13 mm, 25 mm and 60 mm filter Select from several filter configurations, connector, and color options. Single and stepped hose barbs, male threads and female and male luer locks are among the many available connectors. housings can be pad printed with a company logo or other important information in corporate colors as requested. Hot stamping (a highly durable engraving process) is also available in a variety of colors around the circumference of the 50 mm devices. Abbreviations Disk filters can accommodate a wide variety of filter materials, ranging from high flow polyethersulfone, hydrophobic PTFE membrane, woven polypropylene or polyethylene screens and glass microfiber. ML FLL MLL MSF Male Luer Female Luer Lock Male Luer Lock Male Slip Fitting Whatman disk filters are typically supplied in bulk, although these products can also be packaged to customer specifications in blisters, boxes or individual bags. Many choices are available for packaging labeling, including printing on blister backings as well as box and bag labels. FNPT Female National Pipe Thread MNPT Male National Pipe Thread SLPM Standard Liters Per Minute Applications for disk filter products include vents, suction pump protection, equipment and/or sensor protection, insufflation and particulate removal from liquid solutions. Materials PP PES GMF PTFE Polypropylene Polyethersulfone Glass Microfiber Polytetrafluoroethylene NWPP Non-Woven Polypropylene ABS Acrylonitrile Butadiene Styrene PVDF Polyvinylidene Fluoride TEM Track-Etched Membrane [6] F I LT R AT I O N S O L U T I O N S — U N P R E C E D E N T E D P E R F O R M A N C E A N D C H O I C E 4 mm, 13 mm, 18 mm, 25 mm, 30 mm For small volume filtration Whatman has the greatest selection in the industry. Select from several filter configurations, connector options, including many housing and overmold color tints. Female and male luer locks, male slip luers, male slip fitting connectors and tube tips are available. Dimensions (mm) Name 4 mm 23.5 10.1 A wide variety of filter materials can be incorporated into Whatman small volume filters, ranging from PTFE, nylon, PES, GMF and screens. Applications include: equipment and/or sensor protection, syringe filters for hospital pharmacies, particulate removal from liquid solutions and transducer protectors. Typical Membranes Available* Nylon, PTFE, PVDF, PES Housing Description Polypropylene clear, red and blue inlets available Connectors FLL/ML Effective Filtration Area cm2 0.2 13 mm 19.81 19.8 Ø16.26 16.3 FLL/ML 1.3 Nylon, PVDF, PTFE, PES, GMF Polypropylene Pad print available 17.0 17.00 17.0 Ø17.0 13 mm overmolded FLL/ML 0.75 PTFE Polypropylene Color overmold available green, yellow, white, grey, brown Polypropylene Color overmold available green, yellow, white, grey, brown ABS clear and white 13 mm overmolded 17.00 17.0 Ø17.0 17.0 FLL/tube tip 0.75 PTFE Square 13 mm 23.0 16.5 FLL/ML 1.1 Screen, PTFE 18 mm 25 25.0 FLL/MLL 2.3 PTFE ABS 20 20.0 18 mm 25 25.0 ML/ML 2.3 PTFE ABS 20 20.0 21.0 21.00 29.9 Ø29.9 25 mm shortened male luer 25 mm FLL/ML 4.2 Nylon, GMF Polypropylene colored inlet housing green, yellow, brown Pad print available Polypropylene Pad print available FLL/ML 4.2 22.86 22.9 Ø28.45 28.4 PTFE, PVDF, Nylon, GMF, PES, Screen, PP Membrane and NWPP PTFE, PVDF, Nylon, GMF, PES, Screen, PP Membrane and NWPP PTFE, PVDF, Nylon, GMF, PES, Screen, PP Membrane and NWPP PTFE, GMF 25 mm 22.86 24.2 MSF/ML 4.2 Polypropylene Pad print available 28.4 Ø28.45 25 mm 22.86 21.1 FLL/MLL 4.2 Polypropylene Pad print available 28.4 Ø28.45 30 mm 26.0 26.00 34.0 Ø34.0 FLL/ML 5.7 Polycarbonate and Polypropylene Color overmold available red, yellow, green, brown, white, orange Polycarbonate and Polypropylene Color overmold available red, yellow, green, brown, white, orange 30 mm 22.0 2.00 Ø34.0 34.0 FLL/MLL 5.7 PTFE, GMF *Custom Filters using other available membranes can be considered [7] F I LT R AT I O N S O L U T I O N S — U N P R E C E D E N T E D P E R F O R M A N C E A N D C H O I C E 50 mm Disk Filter Housing A compact and efficient design allows 50 mm filters to fit within a variety of critical dimensions. A large number of connector combinations are possible on this versatile and durable filter. The 50 mm disk filter can accommodate a wide variety of filter media including PTFE and screens, which are available in many pore sizes. The lightweight configuration is manufactured using only virgin polypropylene. Typical applications for 50 mm filters include suction pump protection, gas filtration and venting. New Whatman Disk Filter Housing TECHNICAL DATA • Polypropylene Housing 6 mm–14 mm connectors • Currently available with nylon, PTFE* • Effective filtration area: 20.4 cm2 X (ref) • Maximum operating pressure: 65 psi/4.5 bar • Dimensions Width: 63.2 mm Height: 67.2 mm Y (ref) 2.2 (56) (ref) INLET X inch (mm) OUTLET Y inch (mm) 1/4"–3/8" HOSE BARB (6–10 mm) 0.9 (23) 1/4"–3/8" HOSE BARB (6–10 mm) 1.0 (25) 1/4" HOSE BARB (6 mm) 0.9 (23) 1/4" HOSE BARB (6 mm) 1.0 (25) 3/16"–1/4" HOSE BARB (4–6 mm) 1.1(28) 3/16"–1/4" HOSE BARB (4– 6 mm) 1.1(28) 3/8"–1/2" HOSE BARB (9–12 mm) 1.0 (26) 3/8"–1/2" HOSE BARB (9–12 mm) 1.1 (28) 1/8" MNPT 0.8 (20) 1/8" MNPT 0.8 (21) 5/16" - 24 MNPT 0.9 (23) 5/16" - 24 MNPT 1.0 (25) 50 mm Disk Filter – Technical Data • Housing—Polypropylene • Effective Filtration Area: 16 cm2 • Maximum Operating Pressure: 60 psi/4.1 bar FLUSH CONNECTOR 0.4 (10) [8] *Custom filters using other available membranes can be considered F I LT R AT I O N S O L U T I O N S — U N P R E C E D E N T E D P E R F O R M A N C E A N D C H O I C E 60 mm Disk Filter Housing The special housing design of the 60 mm filter allows for high flow rates and lower pressure drop than the 50 mm design. A wide variety of connectors make this filter useful for many applications for filtering air and gas streams. Custom tapered connectors are specially designed to fit directly onto suction canisters, making this filter ideal for suction vacuum protection. The housing is made entirely of virgin polypropylene. Applications for 60 mm filters include suction pump protection, insufflation and air/gas filtration. 60 mm Disk Filters TYPICAL AIR FLOW RATES FOR 60 mm DISK FILTER WITH PTFE MEMBRANE* Air Flow Data Delta P (PSI) vs Flow (SLPM) 16 14 X (ref) INLET Delta P (PSI) 12 10 8 6 4 0.2 µm 0.45 µm 1.0 µm Y (ref) OUTLET 2.5 (64) (ref) 2 0 0 50 100 150 200 Flow (SLPM) 250 300 INLET 1/4" SINGLE HOSE BARB (6 mm) X inch (mm) 1.1 (27) OUTLET 1/4" SINGLE HOSE BARB (6 mm) Y inch (mm) 1.1 (27) 3/8" –1/2" HOSE BARB (9 – 12 mm) 1.2 (29) 3/8"–1/2" HOSE BARB (9–12 mm) 1.2 (29) 1/4" – 3/8" HOSE BARB (6 – 10 mm) 1.1 (27) 1/4"–3/8" HOSE BARB (6–10 mm) 1.1 (27) TAPERED CONNECTOR 0.9 (23) TAPERED CONNECTOR 0.9 (23) 1/8" MNPT 1.1 (27) 60 mm Disk Filter – Technical Data • Housing—Polypropylene • Effective Filtration Area: 25 cm 2 1/4" MNPT 1.1 (27) • Maximum Operating Pressure: 30 psi/2.1 bar *Contact your sales representative for additional technical data F I LT R AT I O N S O L U T I O N S — U N P R E C E D E N T E D P E R F O R M A N C E A N D C H O I C E [9] Capsule Filters Three standard capsule sizes are available. Small, medium and large capsule filters allow the user the flexibility to accommodate a variety of filtrate volumes and placement constraints. Mix and match any combination of connectors, media and housing to create the configuration that best suits your application. All support and housing materials are 100% polypropylene. No adhesives or glues are used. A wide variety of filter materials can be incorporated into Whatman capsule filters. High flow PES is available for use with both liquids and dry gases. Durable hydrophobic PTFE membrane is an excellent choice for aggressive chemical and air/gas stream filtration. Hydrophilic nylon for aqueous solutions and durable non-woven polypropylene depth media for heavy duty fine filtration are also offered. Hydrophobic glass microfiber for high bacteriological efficiency and granulated media help complete the mix of available filtration materials. Polypropylene support materials Granulated media such as carbon or desiccant can be added to the medium and large capsule housings. Applications for this wide range of capsule filter products include equipment and/or sensor protection and particulate removal from aqueous solutions and other liquids, and sterilizing grade filtration for critical point of use applications. Polypropylene housing Pleated membrane cartridge Cut-a-way view of capsule filter [10] F I LT R AT I O N S O L U T I O N S — U N P R E C E D E N T E D P E R F O R M A N C E A N D C H O I C E MEDIUM CAPSULE TYPICAL WATER FLOW RATES FOR MEDIUM CAPSULE WITH NYLON MEMBRANE** 75 mm Nylon Capsules: Water Flow Rates Delta P (PSI) vs Flow (SLPM) 16 14 Technical Data • Housing: Polypropylene • Average Effective Filtration Area: 1000 cm2 * • Maximum Operating Pressure: 60 psi/4.1 bar • Most inlets have a fully threaded vent. Some inlet options are available without a vent. Delta P (PSI) 12 10 0.2 µm 8 6 4 2 0 0 2 4 6 8 0.45 µm 1.0 µm 2.6 (65) (ref) Flow (SLPM) X (ref) INLET Y (ref) OUTLET INLET 1/4"–3/8" HOSE BARB (6–10 mm) X inch (mm) 2.8 (71) OUTLET 1/4"– 3/8" HOSE BARB (6–10 mm) Y inch (mm) 1.8 (46) 3/8" FNPT 3.1 (78) 3/8" FNPT 0.9 (23) 22 mm RESPIRATORY FITTING 4.1 (104) 22 mm RESPIRATORY FITTING 2.0 (50) 1/2" HOSE BARB (12 mm) 3.7 (94) 1/2" HOSE BARB (12 mm) 1.9 (48) 1/4" MNPT 3.7 (94) 1/4" MNPT 1.8 (47) 3/8"–1/2" HOSE BARB (9–12 mm) 4.5 (114) 3/8"– 1/2" HOSE BARB (9–12 mm) 1.9 (48) 1 1/2" SANITARY FITTING 4.4 (102) 1 1/2" SANITARY FITTING 1.7 (43) W/ LEGRIS Q – CONNECT 3.7 (94) 1/2" DRY SEAL THREAD 1.8 (46) *May vary with different membrane or media **Contact your Whatman representative for additional technical data [12] FILTRATION SOLUTIONS — UNPRECEDENTED PERFORMANCE AND CHOICE LARGE CAPSULE TYPICAL WATER FLOW RATES FOR LARGE CAPSULE WITH PES MEMBRANE** 150 mm PES Capsules: Water Flow Rates Delta P (PSI) vs Flow (SLPM) 16 14 12 10 0.1 µm Technical Data • Housing: Polypropylene • Average Effective Filtration Area: 1500 cm2* • Maximum Operating Pressure: 60 psi/4.1 bar • Most inlets have a fully threaded vent. Some inlet options are available without a vent. Delta P (PSI) 8 6 4 2 0 0 5 10 15 20 25 30 35 40 0.2 µm 0.45 µm X 1.0 µm Flow (SLPM) 2.6 (65) (ref) X (ref) INLET Y (ref) OUTLET INLET 3/8"– 1/2" HOSE BARB (9–12 mm) X inch (mm) 6.9 (175) OUTLET 3/8"– 1/2" HOSE BARB (9–12 mm) Y inch (mm) 1.9 (48) 3/8" FNPT 6.2 (157) 3/8" FNPT 0.9 (23) 1/2" HOSE BARB (12 mm) 6.8 (173) 1/2" HOSE BARB (12 mm) 1.9 (48) 1/4"– 3/8" HOSE BARB (6–10 mm) 6.7 (170) 1/4"– 3/8" HOSE BARB (6–10 mm) 1.8 (46) 1/4" MNPT 6.8 (173) 1/4" MNPT 1.8 (46) 1 1/2" SANITARY FITTING 7.5 (191) 1 1/2" SANITARY FITTING 1.7 (43) 22 mm RESPIRATORY FITTING 7.2 (183) 22 mm RESPIRATORY FITTING 2.0 (50) W/ LEGRIS Q – CONNECT 6.8 (173) 1/2" DRY SEAL THREAD 1.8 (46) *May vary with different membrane or media **Contact your Whatman representative for additional technical data [13] F I LT R AT I O N S O L U T I O N S — U N P R E C E D E N T E D P E R F O R M A N C E A N D C H O I C E SMALL CAPSULE TYPICAL AIR FLOW RATES FOR SMALL CAPSULE WITH PTFE MEMBRANE** Air Flow Rate — 36 mm Teflon® Delta P (PSI) vs Flow (SLPM) 6 Technical Data • Housing: Polypropylene • Average Effective Filtration Area: 500 cm 2* • Maximum Operating Pressure: 60 psi/4.1 bar • Most inlets have a fully threaded vent. Some inlet options are available without a vent. 5 ✱ Delta P (PSI) 4 0.1 µm 0.2 µm 3 ✱ 0.45 µm 1.0 µm 2 ✱ 1 ✱ 0 ✱ 0 50 100 150 200 Flow (SLPM) 2.6 (65) (ref) X (ref) INLET Y (ref) OUTLET INLET 22 mm RESPIRATORY FITTING X inch (mm) 2.2 (56) OUTLET 22 mm RESPIRATORY FITTING Y inch (mm) 2.0 (50) 3/8" FNPT 1.2 (30) 3/8" FNPT 0.9 (23) 1/4"– 3/8" HOSE BARB (6 –10 mm) 1.7 (43) 1/4"– 3/8" HOSE BARB (6–10 mm) 1.8 (46) 3/8"– 1/2" HOSE BARB (9 –12 mm) 1.8 (46) 3/8"– 1/2" HOSE BARB (9–12 mm) 1.9 (48) MOLDED LEGRIS Q—CONNECT 1.8 (46) 1/2" DRY SEAL THREAD 1.8 (46) 1/4" MNPT 1.8 (46) 1/4" MNPT 1.8 (46) 1 1/2" SANITARY FITTING 2.5 (64) 1 1/2" SANITARY FITTING 1.7 (43) 1/2" HOSE BARB (12 mm) 1.8 (46) 1/2" HOSE BARB (12 mm) 1.9 (48) *May vary with different membrane or media **Contact your Whatman representative for additional technical data [11] F I LT R AT I O N S O L U T I O N S — U N P R E C E D E N T E D P E R F O R M A N C E A N D C H O I C E S P E C I A LT Y P R O D U C T S Transfersets The innovative Whatman Transferset facilitates the reconstitution of Factor VIII and Factor IX lyophilized drug preparations. The Transferset is designed for use only with lyophilized drug preparations in vacuum bottles or vials. The unique design of the product and cannula provide several important advantages: • Simplifies reconstitution of lyophilized drugs • Eliminates contamination: anticoring lancet minimizes particles generated and the special tip easily pierces the bottle’s rubber stopper without punching rubber particles into the product • Joins two vials with a stable and rigid connection • Cyclonic liquid flow ensures the drug is quickly and completely dissolved and that the lyophilized product will not compact Whatman Transferset Spikes Whatman offers a line of filter spikes for small-volume filtration and venting. Whatman vent spikes contain hydrophobic PTFE membrane for venting. Some devices also contain a hydrophilic 5 µm or 20 µm polyester screen filter for particle retention. Vent spikes allow vented aspiration during liquid extraction from storage bottles and vials. Particulate filters prevent foreign particulate matter such as undissolved drug or rubber pieces from the vial from contaminating the liquid being extracted. Vent spike Vent spike with 5 µm particulate filter 20 µm particulate filter spike 13 mm vent needle 18 mm vent needle [14] F I LT R AT I O N S O L U T I O N S — U N P R E C E D E N T E D P E R F O R M A N C E A N D C H O I C E Reservoir Filters Whatman has small volume filter units that have reservoirs available for activated carbon and/or desiccants to remove odor or humidity from gas streams. Final filtration is a 0.2 µm PTFE membrane filter. Compact In-line Air/Gas Filters Whatman offers a special capsule design for in-line air/gas filtration. Two different hose barb connectors are available to fit either 1⁄4 inch or 3⁄8 inch (6 mm to 10 mm) I.D. tubing. These filters are ideal for use in low pressure applications such as infant respiratory therapy. Elliptical and 60 mm Insufflation Filters Whatman produces a special line of 60 mm and Elliptical disk filters specially designed for filtering CO2 gas used in minimally invasive surgery. Laparoscopic procedures typically require the use of an insufflator to pump clean CO2 gas into a patient's body cavity to inflate it and thereby facilitate the surgery. Whatman insufflation filters contain a special ULPAplus™ filter media which is rated in air to retain particles ≥ 0.1 µm at 99.99% and provides a hydrophic barrier to contain a column of aqueous liquid for 5 minutes @ 1 psi pressure. 60 mm insufflation filters are available with a variety of hose barb connectors and is suitable for insufflators with flow ≤ 20 SLPM. The Whatman Elliptical insufflation filter is suitable for flow > 20 SLPM. 3.7 in. (94 mm) Carbon and Dessicant Reservoir Filters 1.9 in. (48 mm) 3 ⁄8" Hose Barb Air/Gas Filter Screen Reservoir Filter 3.7 in. (94 mm) Another reservoir filter has a rigid clear ABS housing with a small chamber and is available with hydrophobic polyester screen. 1 FLOW FLOW 1.9 in. (48 mm) Elliptical Filter Technical Data • Housing: Polypropylene ⁄4" Hose Barb Air/Gas Filter • Effective Filtration Area: 40 cm2 • Connectors: 1⁄4"– 3⁄8" (6–10 mm) hose barbs • Inlet Pad Printed Insufflator Side Small Air/Gas Filters [15] F I LT R AT I O N S O L U T I O N S — U N P R E C E D E N T E D P E R F O R M A N C E A N D C H O I C E C U S T O M I Z AT I O N O P T I O N S Custom labeling and packaging is available for your OEM filter. Several methods are available for adding your company logo and important product information to your filter. The four labeling methods are listed here. Please note that certain products can only accommodate certain types of labeling (compatible products are listed under each category). A wide variety of bags, boxes, jars, blisters and peel pouches are available. EtO and gamma sterilization methods are also available. Adhesive Labels Can be affixed directly to the capsule or on the outside of a box or bag for any product in the line Adhesive labels can be made from a variety of materials depending on the environment in which they will be used. Whatman offers materials which can withstand multiple autoclave cycles without ink smearing or fading. Special coated labels are available for products that must endure aggressive solvents. Hot Stamping For use on 50 mm mold rings and the flat surface of the capsule outlet This process allows highly durable and legible text to be engraved directly into the filter housing, an ideal solution for filters that must endure adverse conditions. Standard hot stamp colors include red, blue, green and black. Adapters Threaded connectors can accommodate spin-welded or hand-sealed adapters Along with the wide variety of molded connector options for Whatman OEM filters we can also incorporate custom adapters of your choice in many of the capsule filters or threaded connector disk filters. Hot Stamp Labels Pad Printing 60 mm, Elliptical and Capsule housings can be pad printed, as well as selected 4 mm, 13 mm and 25 mm filters Pad printing is a high resolution ink transfer process which produces clean sharp images. It allows for some design latitude, such as adding your company logo. Standard ink colors include red, blue, green and black. Printed Blister Lids For use with blister packaged 25 mm and 50 mm filters as well as peel pouch packaged products Tyvek® seals blister and most peel pouch packaged filters. This material can be printed to your specifications. Your information (logo, lot number, expiration date, etc) can be printed directly onto Tyvek® in your choice of color. (Peel pouch packages can also be enclosed with paper.) Custom Adapters Pad Printing Sterile Packaging [16] F I LT R AT I O N S O L U T I O N S — U N P R E C E D E N T E D P E R F O R M A N C E A N D C H O I C E F I LT R AT I O N B A S I C S A N D D E S I G N C O N S I D E R AT I O N S WHICH WHATMAN PRODUCT IS RIGHT FOR YOUR APPLICATION? Choosing the filtration solution that specifically addresses your unique product development and application needs can be an extremely complex process. A host of factors related to performance, chemical properties and configuration ultimately determine which filter options are right for you. This section provides a brief overview of filtration design, purpose and functionality. For in-depth, expert consultation on filtration evaluation and selection, please contact your Whatman representative. • Filter media: Although there are numerous types of filter media, those most commonly used are described below. As a broad classification, there are two trapping mechanisms: (1) membranes and woven media rely on surface retention, whereby the pore/mesh size determines the capture capabilities; and (2) depth filters trap particles within their layered matrix. • Hydrophilic vs hydrophobic: Hydrophilic media attracts water and can be wetted; hydrophobic repels water and can only be wetted with low-surface tension liquids, making it ideal for gas filtration and venting applications. • Pore size: Ratings refer to the size of a specific particle or organism retained by the filter media to a specific degree of efficiency. Nominal pore ratings refer to the media’s ability to retain the majority of the particulates at the rated pore size and larger. Absolute pore size ratings indicate the pore size at which a challenge organism of a particular size will be retained with 100% efficiency under defined test conditions. • Extractables: The contaminants that elute from the filter media and may adversely affect effluent quality. Extractables may include wetting agents in the filter media, manufacturing debris, sterilization residue or adhesives. • Flow rate and throughput: Viscosity determines a liquid’s resistance to flow. The higher a liquid’s viscosity, the lower the flow rate and the higher the differential pressure required to achieve a given flow rate. • Porosity: Porosity is the measure of all pores in a membrane; more pores yield higher flow rates. QUESTIONS TO CONSIDER WHEN DESIGNING YOUR FILTER: • Application: What is the function of the filter? • Compatibility: What solution (liquid or gas) will be filtered? • Volume: How much will be filtered, and for how long? • What flow rate is necessary? At what DP (Differential Pressure)? • What retention value is necessary (Absolute/Nominal)? • What connectors are ideal for the product? • Size constraints? • Filter media preference? • Does the filter need to be hydrophilic or hydrophobic? • Temperature requirements? • Sterilization: Does the product need to be sterile? If so, by what method? • Is the product a medical device? • Does the product need to be reusable or disposable? • Special packaging required? [17] F I LT R AT I O N S O L U T I O N S — U N P R E C E D E N T E D P E R F O R M A N C E A N D C H O I C E Whatman Quality Whatman is a global leader in separations technology and is known in the scientific community for providing Innovative Life Science products and solutions. Our instinct for simplification accelerates the rate of discovery, reduces costs and saves time. For more information, visit www.whatman.com Anopore® and Whatman® are registered trademarks of the Whatman Group. ULPAplus™ is a trademark of Whatman. Tyvek® is a registered trademark of DuPont. North America Whatman Inc. 200 Park Avenue, Suite 210 Florham Park, NJ 07932 USA Tel: 1-800-WHATMAN (US and Canada) Fax: 1-973-245-8329 Email: info@whatman.com Whatman International Ltd. Springfield Mill, James Whatman Way Maidstone, Kent ME14 2LE UK Tel: +44 (0)1622 676670 Fax: +44 (0)1622 677011 Email: information@whatman.com Whatman GmbH Hahnestrasse 3 D-37586 Dassel Germany Tel: +49 (0) 5564 204 100 Fax: +49 (0) 5564 204 533 Email: information@whatman.com Your Whatman team can offer a wealth of technology to support your filter device needs – whether for a standard product, or a custom filter for an innovative new development. A team of experts dedicated to devices ensures rapid and efficient design and development of your concepts. Nowhere is this more apparent than in our relationships with OEM Manufacturers. Quite simply, given our in-depth understanding of the filtration industry, OEMs don’t consider us suppliers; they consider us their filtration partners. Europe Japan Whatman Japan KK JPR Ichigaya Building 6F 4-7-15 Kudan-Minami, Chiyoda-ku, Tokyo 102-0074 Japan Tel: +81 (0)3 5215 1240 Fax: +81 (0)3 5215 1245 Email: japaninfo@whatman.com Whatman Asia Pacific Pte Ltd. 1 Kim Seng Promenade #15-12 Great World City, West Tower Singapore 237994 Tel: +65 6534 0138 Fax: +65 6534 2166 Email: wap@whatman.com Asia Pacific 51704 (US) S9036-2164 (EU) 10/06

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