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					AUSTRALIA




                             DNA CHARACTER
                                                                                SILVER JEWELRY

                                   OPERRATION PLAN



            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226
AUSTRALIA                                     TABLE OF CONTENTS


                                    1. Operation Overview ------------------------------ 3

                                    2. Organization ------------------------------------ 4

                                    3. DNA Information
                                        3.1 Introduction ----------------------------- 5
                                        3.2 Genome Structure --------------------- 6
                                        3.3 Gene Sequence ----------------------- 7
                                        3.4 DNA Sequence ----------------------- 8
                                        3.5 The DNA Character ---------------- 9
                                        3.6 STR ------------------------------- 10
                                        3.7 HVR ----------------------------- 11

                                    4. Work Process
                                        4.1 Collecting Specimen ------- 12
                                        4.2 Handling Specimen ------- 13
                                        4.3 DNA Testing ------------- 14
                                        4.4 Legal DNA Testing ----- 15
                                        4.5 DNA Preservation ----16

                                    5. Other Concerns --------17

            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   2
AUSTRALIA                                     1. OPERATION OVERVIEW


                  DNA CHARACTER PRODUCT

                  Dr. LEE CORPORATION will establish a new business that provides DNA
                  character products. The concept of the business is to commercialize basic/medium
                  level of DNA technology as jewelry, accessories, memorials, etc. The proposed
                  business will provide DNA abstract products, personal identifying DNA products,
                  DNA photographic products, etc. Major target customers will be consumer group
                  who is interested in jewelry and personal/family identity.

                   THE WORK PROCESS

                  -   Collecting orders from clients through DNA Character Shops and Website
                  -   Collecting DNA Samples (Specimen) with orders (Hair, Swab-Cheek etc)
                  -   Post the Specimen to the DNA testing laboratory.
                  -   DNA testing is processed in the laboratory
                  -   Selecting DNA identification from the profile
                  -   Produce the Silver Jewelry with the identification embossed




            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   3
AUSTRALIA                                     2. ORGANIZATION




                                                  MANAGING DIRECTOR




                                        FINANCE               MARKETING            DNA LABORATORY



                                     MANAGEMENT              DESIGN/SALES               TESTING




            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   4
AUSTRALIA                                     3. DNA INFORMATION

1. INTRODUCTION
                  Fifty years ago scientists first described the structure of deoxyribonucleic acid (DNA).
                  Today humans have put DNA to work in a wide variety of applications.


                  Throughout the body > in cells...

                  Human body consists of cells with the number of about 50 and 100 trillion cells (a
                  trillion is a thousand billion, or a thousand, thousand million). These cells are
                  organized into tissues, such as skin, muscle, and bone. Each cell contains organism's
                  all of the genetic information stored as DNA. However, each cell uses only the
                  information from part of the DNA, which is called tissue specific expression. For
                  example, a muscle cell uses the DNA that specifies the muscle apparatus, whereas a
                  nerve cell uses DNA that specifies the nervous system. It is as if each cell reads only
                  that part of a book of instructions that it needs.
                  Within the cell > in chromosomes...

                  Each very long DNA molecule is tightly wound and
                  packaged as a chromosome.
                  Humans have two copies of 23 chromosomes in every
                  cell, one set inherited from each parent.
                  A human cell therefore contains 46 of these
                  chromosomal DNA molecules.


            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   5
AUSTRALIA                                     3. DNA INFORMATION

2. GENOME STRUCTURE

                  Within each chromosome > in genes...

                  Each DNA molecule that forms a chromosome
                  can be viewed as a set of shorter DNA sequences.
                  These are the units of DNA function, called
                  genes, each of which guides the production of
                  one particular protein of an organism. A set of
                  human chromosomes contains one copy of each
                  of the roughly 30,000 genes in the human
                  "genome" - the term used to refer to the
                  complete genetic instructions for an organism.


                  Are People Really Identical?

                  Even though humans share 100% of the same
                  genes, the information contained within the
                  genes are not entirely identical. Each person has
                  their own unique DNA sequence. People have
                  different hair colors, facial structures, and other
                  traits. These differences between individuals
                  result from very small differences in their DNA
                  sequence.

            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   6
AUSTRALIA                                     3. DNA INFORMATION

3. GENE SEQUNCE
                  Two Copies of the Genome

                  Human Inherits One Copy From Each Parent
                  A person has two copies of every gene sequence, one inherited from the mother,
                  and the other inherited from the father. A child thus inherits one copy from each
                  parent's own pair, and this copy is selected from the parent randomly. In order to
                  fully understand a person's DNA sequences, both inherited copies of a gene need to
                  be examined.

                  These sequences are often not identical. Gene
                  sequences for so-called "dominant" traits are expressed
                  over "recessive" traits. Do you have a cleft chin? It is an
                  indentation at the tip of your chin. If so, you have at
                  least one copy of the dominant gene for cleft chin. But if
                  your chin has no indentation, you have two copies of the
                  recessive gene for this trait.

                  Inherited Disease

                  Just as a children may inherit their hair or eye color from
                  their parents, they can also inherit genetic diseases. In
                  dominant trait, if a child inherits just one mutated copy
                  of the gene he or she is a "carrier" of the genetic disease.
                  If there are two defective copies the child may be
                  affected by the disease.

            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   7
AUSTRALIA                                     3. DNA INFORMATION

4. DNA SEQUENCE     The DNA Sequence
                   The extremely long DNA molecule is actually made of a long string of chemical
                   building blocks called “nucleotides.” There are four different nucleotides, which are
                   labeled adenine A, thymine T, guanine G, and cytosine C. The human genome is
                   made of a sequence of roughly three billion of these nucleotides.
                   Although 99% of DNA sequence is identical in each individuals, there are
                   polymorphic markers, which we call micro-satellite or SNPs. These polymorphic
                   markers are used for Identification purpose.
                    What part of DNA sequence is used for DNA Character item?

                                                                                         Functional Sequence
                                                                                         for phenotype and Gene


                                                                                         Polymorphic Sequence for
                                                                                         Identification


                                                                                         DNAtyping
                                                                                         forensic and ID use


                                                                                         STR + HVR : a part of the
                                                                                         Mitochondria DNA Sequence


                                                                                         Engraving the Code on items


            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226      8
AUSTRALIA                                     3. DNA INFORMATION

5. THE DNA CHARACTER

                 The ‘DNA Character’ is a way of creating a DNA identity code named by Dr.
                 J.I.Lee.
                 It is a patented formula of combining the number of repeat counted on DNA
                 Sequencing (STR, Short Tandem Repeat ) and the HVR (Hypervariable
                 Region) section of the Mitochondria.
                 Ex) 73-249-263-C1(305)-C2(315)/G-D-G-8-6 DYS385/392/19;10-17/13/15<

                                                          Our DNA


                                            In Nuclear                 In Cytoplasm



                                      Genomic DNA                      Mitochondrial DNA


                              STR - Characterized                      HVR - Characterized
                              by Numbers                               by A.T.G.C.




            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   9
AUSTRALIA                                     3. DNA INFORMATION

6. STR
                  STR Polymorphisms

                  Most of our DNA is identical to DNA of others. However, there are inherited
                  regions of our DNA that can vary from person to person. Variations in DNA
                  sequence between individuals are termed "polymorphisms".

                  As we will discover in this activity, sequences with the highest degree of
                  polymorphism are very useful for DNA analysis in forensics cases and
                  paternity testing. This activity is based on analyzing the inheritance of a
                  class of DNA polymorphisms known as "Short Tandem Repeats", or simply
                  STRs.

                  STRs are short sequences of DNA, normally of length
                  2-5 base pairs, that are repeated numerous times in
                  a head-tail manner,
                  i.e. the 16 bp sequence of "gatagatagatagata" would
                  represent 4 head-tail copies of the tetramer "gata".
                  The polymorphisms in STRs are due to the different
                  number of copies of the repeat element that can
                  occur in a population of individuals.
                  Ex) 12-11, 13-11,7-15




            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   10
AUSTRALIA                                     3. DNA INFORMATION

7. HVR            The HVR section of the Mitochondria

                                        hypervariable region in mitochondria describes who you are,
                  The DNA sequence of STR
                  and is used for personal identification as well as STR.



                                         HVR (Hypervariable Region)




                                     Variation of Mitochondria DNA Sequence

                                                                                                        100,000 times




            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   11
AUSTRALIA                                     4. THE WORK PROCESS

1. COLLECTING SPECIMEN



                                    Collecting orders from clients through the „DNA Character Shop‟ and
                                    the Website. The first DNA Character Shop will be open in Victoria
                                    from middle of year 2006” followed by direct order facilitated website.



                                    The client at the shop or website will choose the jewelry product and
                                    agree with the condition of providing the specimen for DNA Testing.
                                    (Consent form will be signed on)



                                    The „Specimen Collecting Kit‟ will be handed out person to person in
                                    the shop. The same kit will be posted out by Australian Post to the
                                    website client with a return envelop.


                                    The kit contains BUCCAL swabs and return envelope (for mail order).
                                    Taking the sample is simple by just wiping the buccal swab inside of
                                    the cheek. A buccal swab looks like a long Q-tip. The head of the
                                    swab is firmer than the head of a regular cotton swab.



            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   12
AUSTRALIA                                     4. THE WORK PROCESS

2. HANDLING SPECIMEN

                    SHOP : The specimen will be handed in person to person.
                    The Collected specimen will be sent out to the lab by Australian Post.
                    When DNA Testing is completed, the specific result data will be returned to the
                    shop by email or fax.




                                                                   email


                    WEBSITE : The „Specimen Collecting Kit‟ will be posted out to the client. Once
                    the BUCCAL swab is done the client will post it out to the lab with the return
                    envelop enclosed. This return envelop will go to the lab directly by Australia post.




                                                                                                     email



            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   13
AUSTRALIA                                     4. THE WORK PROCESS

3. DNA TESTING

                                     COMPLIANCE

                                     For the nature of our DNA ID data use, the DNA Testing facility does
                                     not have to be a NATA accredited laboratory. (National Association of
                                     Testing Authorities Australia www.nata.com.au )


                    In the first stage of the business we are going to use a Korea based and well
                    established existing DNA Testing Laboratory.

                    To be a recognized and reputable DNA testing company as well as a successful
                    DNA Character Jewelry business, we plan to extend our business to a DNA Testing
                    Laboratory Service in full scale at the second stage of the business. This service
                    will include Paternity, Sibling-ship Analysis and Forensic Test, as well as DNA
                    Preservation. Legal evidence service will be included.


                                             1st STAGE                            2ND STAGE



                                      OUT SOURSED LAB                         ACCREDITED LAB



            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   14
AUSTRALIA                                     4. THE WORK PROCESS

4. LEGAL DNA TESTING

                  What is the difference between a Legal Test and Peace of Mind Test?

                  The difference between a peace of mind case and legal case is the “witnessing” of
                  the samples and the paper trail that is behind the testing.
                  As the legal cases are required by the court or immigration authority we need to
                  make certain that the samples are from the correct person.
                  The doctor or witnessing party will review photo identification and associated
                  paperwork before placing into a tamper proof bag.
                  This assures the appropriate court/authority that the samples are coming from the
                  correct individuals and is a mandatory requirement.

                  Court Related Paternity Test

                  In the 2nd stage of our service will provide court admissible
                  DNA and paternity tests used for paternity disputes and
                  immigration cases those often occur in Australia and from
                  overseas.
                  Collection kits are sent directly to a recommended practitioner
                  or GP in your local area. DNA Test results can be used to
                  amend and change birth certificates.




            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   15
AUSTRALIA                                     4. THE WORK PROCESS

5. DNA PRESERVATION
                  Due to the accelerated advances made in medical science concerning genetic links
                  to diseases, DNA preservation after the DNA Test done or, sampling before burial or
                  cremation is an option.
                  The information gained from a preserved DNA sample can be of invaluable benefit
                  to the client and his/her future generations.
                  Furthermore, because of its world-wide acceptance as the most finite form of
                  identity, DNA preservation can conclusively resolve future estate, parentage,
                  immigration and inheritance issues for all.

                  We already know that some of the biggest killers are inherited genetic disorders.
                  In fact it has been scientifically proven that 75% of all diseases can be traced to a
                  family‟s genetic makeup. Some of these include..
                  -   Coronary heart disease
                  -   Numerous cancers but particularly breast,
                  -   ovarian and colonic cancers Cystic fibrosis
                  -   Alzheimer‟s disease
                  -   Liver and kidney diseases

                  Consent For DNA Preservation
                  Client who is taking the DNA Test for Jewelries has option to preserve their DNA Test
                  result data and samples to be reserved. The sample will be stored in a deep freezer
                  for future use. We need to have a signed consent form for this process.
                  Otherwise the sample will be terminated but DNA data will be kept in a secured DB.


            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   16
AUSTRALIA                                     5. OTHER CONCERNS


                  Privacy

                  Privacy needs to be assured.
                  The client‟s sample will not be used by the company or its employees for research
                  or any genetic analyses.
                  The profiles and any additional tests results are kept in strict confidence.
                  The information is only available to the next of kin or other legally authorities.
                  Our privacy policy will be addressed in many forms.
                  Commonwealth government is currently implementing new policy that states that
                  an individual can not be unfairly discriminated against on the basis of his or her
                  genetic characteristics. This covers all insurers and employers too.


                  Ethics

                  - National Health and Medical Research Council
                  - Medical Research Ethics Committee


                  Any law against us?



                                                                 Only seriouslyto DB
                                                                  mindaccess to!file
                                                                   Not even privacy
                                                                   No your to Bush
                                                                    No talk
                                                                       access
                                                               Wevery Dog is allowed


            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   17
AUSTRALIA




                            DNA CHARACTER                                   SILVER JEWELRY




                                DR LEE CORPORATION PTY LTD
                                DR LEE CORPORATION PTY LTD




            2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226
              2 Margaret Street, Oakleigh South, Victoria 3167 Australia Tel : 61-3-9544-1191, Fax : 61-3-9543-1226   END

				
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posted:9/21/2011
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