CTSA Collaborative Vision

The CTSA Collaborative Vision Anthony Hayward June 23, 2008 Impact: this meeting matters • 38 of 60 CTSAs funded: over half way there! • 54% of the NIH’s extramural finding goes to 60 institutions • The 38 institutions with CTSAs received 41% of NIH’s extramural funds in 2008 • CTSA Consortium Oversight Committee’s strategic planning process has started and will be focus of October 2008 meeting Pediatrics has a Voice: at least 17 Children’s Hospitals participate in CTSAs • • • • • • • • • • • • • • • • • St. Louis Children’s Hospital (Wash U) Children’s Hospital and Regional Medial Center (Wash) American Family Children’s Hospital (Wisconsin) Children’s Healthcare of Atlanta (Atlanta CTSI) CHOP (Penn) Children’s Hospital of Pittsburgh (Pitt) Children’s Oakland Hospital (UCSF) The Children’s Hospital at Montefiore (Einstein) Children’s Hospital Boston (Harvard) Children’s Memorial Hospital (Northwestern) Nationwide Children’s Hospital (Ohio) Children’s Health System (Alabama) The Children’s Hospital (Colorado) CHRISTUS Santa Rosa Children’s Hospital (UTHSC – San Antonio) Primary Children’s Medical Center (Utah) Kennedy Krieger Children’s Hospital at John Hopkins University Rady Children's Hospital, San Diego (Scripps) Clinical and Translational Science Awards provide essential resources for pediatric researchers NIH & other government agencies Clinical Research Ethics Trial Design Biomedical Informatics CTSA HOME Advanced Degree-Granting Programs Industry Community Involvement for Research & Education Clinical Resources Biostatistics Regulatory Support Healthcare organizations Impact: the Consortium • Sharing best practices • Identifying consortium priorities improved clinical research management curriculum development registering resources better biobanking • Speaking with a common voice CTSA philosophy • Serve NIH funded investigators, including all types and sizes of studies and clinical disciplines • Increase the efficiency and speed of clinical and translational research • Integrate translational and clinical science by fostering collaboration between departments and schools of an institution and between institutions and industry Are we succeeding? • Congress sensitive to: needs of the public needs of clinical researchers • Public needs ranging from education to participation • Clinical researchers • NIH investigators funded by individual Institutes and Centers Congressional priorities • 2006 NIH Reform Act: Pediatrics • 2001 Clinical Research Enhancement Act • A national network • Institutional development awards Centers of Biological Research Excellence (COBRE) Institutional networks (INBRE) CTSAs — Building a National Consortium Currently 38 awards across the nation Northwestern University University of Colorado, Denver WA MT OR ND MN ID WY NE UT IA IL CO CA KS MO TN KY NC IN OH WV SD WI MI PA MD NJ DE NY VT NH MA RI CT ME Ohio State University Harvard University Boston University Tufts University Albert Einstein College of Medicine University of Utah NV Stanford University VA Indiana University School of Medicine University of North Carolina Scripps Research Institute AZ NM OK AR MS AL GA SC AK TX LA University of Alabama, Birmingham FL HI University of Texas Health Science Center at San Antonio Participating Institutions Members 2006 & 2007 New Members 2008 PR Can outreach fill some gaps? • In the local environment? Within and outside the awardee institution. • At a regional level? Self assembly of regional networks • At a consortial level? Flexible governance structure Illustrating local agreements: the Atlanta-CTSI at Emory University Kaiser Permanente Yerkes NPRC CDC Georgia Bio Emory University Children’s Healthcare of Atlanta Morehouse School of Medicine Georgia Tech Atlanta VA Medical Center Georgia Research Alliance West Coast Alliance    56 representatives from all four west coast CTSA institutions Opportunities to collaborate and share strengths Focus on building investigator and scientific collaborations— opportunities across centers University of Washington Oregon Health and Science University University of California, Davis University of California, San Francisco Upper Midwest Alliance    Representatives from at least nine institutions Opportunities to collaborate and share strengths Focus on building investigator and scientific collaborations— opportunities across centers University of Minnesota Mayo Clinic University of North Dakota University of Wisconsin University of South Dakota University of Chicago University of Nebraska University of Iowa Washington University Consortium Governance & Organization Governance Manual available at http://ctsaweb.org/Docs/CTSA_Governance_Manual.pdf Opportunities for pediatric research • Take this opportunity to develop consensus • Take this opportunity to develop common vocabularies and data standards • Speak with a common voice – – – – Pediatric research education Pediatric IRB issues Feedback to researchers Enrolment into studies • Participate in the strategic planning process – Speak with the PI at your site Essential reading www.ctsaweb.org https://www.ctsawiki.org/wiki//x/TQAk https://www.ctsawiki.org/wiki/download/attachments/2359373/may0812ctsaconsortiumpriorities.doc?version=1 Number of awards supported at CTSAs in 2007 GM AR DA HD AT AA NR DE H MD EBHSGDP ESDC EY FDDD DK HL AG AI MH NS CA Awards supported through CTSAs 2007 HD DA MH DP HS FD DCHG AA AT MDDD ES NR EYEB GM DE AR CA AG DK NS AI HL A wealth of resources: details at www.ctsaweb.org