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                                    FROM CONCEPT AND PROTOTYPE
                                    TO CLINICAL TRIAL AND MANUFACTURE
A C C E L E R AT I N G H I G H - T E C H B U S I N E S S S U C C E S S
         FROM MAYOR                                                                                    A 506-ACRE
D O N P L U SQ UELLIC                                                                                INNOVATION DIS T R I C T
   Akron remains one of America’s most innovative communities.
More than 100 years ago, Akron became a center for international business through our
dominance of the rubber and tire industry. Today Akron is an international center of materials
innovation, research, and development.

That’s why in 2006 I announced the creation of the Akron Biomedical Corridor. The Corridor will               Established in July 2006, the Akron Biomedical Corridor
meld our established expertise in materials science and technology with Akron’s burgeoning
healthcare-related research and development activities, our growing number of biomedical
                                                                                                              is a 506-acre area which arcs around downtown Akron
companies, and the region’s exceptional workforce.
                                                                                                              and connects the campuses of three world-class hospitals
Akron’s three hospitals – all ranked nationally by independent rating entities – host more than
1,300 beds, 1.5 million annual outpatient visits, and 80,000 patient admissions to provide the
                                                                                                              – Summa Health System, Akron General Medical Center,
ideal environment for effective clinical trials, market testing, and advanced purchasing.
                                                                                                              and Akron Children’s Hospital.
I am committed to making the Akron Biomedical Corridor a world-class Innovation District. We
have an established record of doing what it takes to attract growing companies to our city and       Bordering The University of Akron’s campus, the Corridor is also
support them after they arrive. We have assembled a comprehensive program that includes
financial incentives, low-cost space, and a specialized business development team to help new         located near important biomedical research taking place at the
companies establish a presence in Akron and successfully grow their business.
                                                                                                     hospitals, The University of Akron, Northeastern Ohio Universities
More than 25 international companies are pleased to call Akron home. Guests find a welcoming
environment, with friendly people who greatly prize the quality of life they have built around the   Colleges Of Medicine and Pharmacy (NEOUCOM), and Kent
arts, a national park, and more than 20 institutions of higher education. Akron-Canton Airport is
one of the fastest-growing in the United States, with direct flights daily to New York, Boston,       State University.
Chicago, Atlanta, Denver, and more. (It’s not unusual for an Akron professional to spend the
       day in New York and be home in time to put the children to bed!)                              This unique geographic location offers new businesses exciting
         Why should you give Akron another look? Our geography, our history, our quality of          opportunities for strategically located development sites as they
         life, and our being named one of Newsweek magazine’s top-10 “hot-tech” cities in
          America, all position Akron as a place where we speak the language of business.            work to advance innovative biomedical technologies, products,
           Our team welcomes the opportunity to discuss your company’s promising future              and services, as well as conduct clinical tests and preliminary
          in Akron, Ohio, U.S.A.
                                                                                                     test marketing.

            AKRON’S                                                                                     NATIONALLY
      C O M P ET I T I V E AD VAN TAG E                                                               R ANKE D HOS PI TAL S
                                                                                                                Akron is home to Summa                      Ranked in the U.S. News &
                                                                                                                Health System, Akron                        World Report “America’s Best
                                                                                                                General Medical Center,                     Hospitals 2006”:
                                   NEW YORK
                                                Recently ranked by Site Selection                               and Akron Children’s
                    CLEVELAND                                                                                                                                 Summa Health System’s specialties include
CHICAGO                                         magazine as #2 for new and                                      Hospital – three top-notch
                                                                                                                                                              respiratory disorders, cardiac care, endocrinology,
                                                expanded facilities among midsized                              healthcare institutions                       orthopaedics, digestive disorders, and
                                                U.S. metropolitan areas, Akron:                                 employing a total of more                     infectious diseases.
                                                                                                      than 11,000 physicians, specialists,
                                                                                                                                                              Akron General Medical Center treatment and
                                                  Leads other cities in cultivating international     technicians, and staff in downtown                      research specialties include heart and heart
                                                  connections and identifying and capitalizing        Akron. Collectively, all three                          surgery, respiratory disorders, cancer, and

                                                  high-tech and biomedical companies wanting to       hospitals provide:                                      orthopaedics. The facility has an animal testing

                                                  enter the U.S. marketplace to sell products and

                                                                                                                                                              lab and an orthopaedic mechanical testing facility.

                                                  accelerate innovative research.                      More than 1,300 beds to meet the medical and
                                                                                                                                                            Akron boasts an additional competitive strength in
                                                  In partnership with state officials and Team Ohio,    research needs of the region.
                                                                                                                                                            Akron Children’s Hospital, a full-service pediatric
                                                  has aggressively marketed Ohio and Akron             More than 1.5 million annual outpatient visits and   medical center for children and burn victims of all
                                                  through outreach efforts to Israel, Germany,         80,000 patient admissions – a combined total         ages. Each hospital has recently embarked on major
                                                  and China.                                           greater than that of the Cleveland Clinic.           expansions, renovations, and capital investments.
                                                  Is known for its friendly and smooth interaction
                                                  with the business community. Akron’s strong
      With a population of close to 650,000       collaboration between the city and private
                                                  business creates a fertile environment
      in the metropolitan area, Akron is          for business growth.
      one of the largest cities in Ohio.                                                                OUTSTANDING RESEARCH AND
                                                Distinguished for its world-class
      The city is within a 500-mile radius of
      42 major U.S. cities that encompasses:
                                                reputation as the center of polymers
                                                and advanced materials, Akron                         M E DI CAL I NS TI TU TI O N S
                                                is poised to become the strategic
                                                location for innovative
      OF ALL
                                                biomedical companies.
                                                                                                      Two major academic institutions                         NEOUCOM is a community-
                                                                                                                                                              based state medical school
                                                Businesses can also take advantage                    are located in or easily accessible
                                                of the area’s abundance of                                                                                    program with research specialties
                                                                                                      to Akron:                                               in skeletal biology, infectious
           57 %
                                                existing research in technical-
                                                and healthcare-related industries,                     The University of Akron is among the 75
                                                                                                                                                              diseases cardiovascular medicine,
                                                                                                                                                              neuroscience, and clinical outcomes. The
                                                as well as a high-quality workforce                    largest public universities in the country, with
                                                and access to exceptional transportation networks.                                                            NEOUCOM consortium includes its medical
                                                                                                       an enrollment of 24,000 students and 800 full-
                                                                                                                                                              college campus, three state universities,
       60 %
                                                In short, Akron offers a powerful synergistic
                                                combination of nationally ranked hospitals,
                                                                                                       time faculty members. The university’s College
                                                                                                       of Polymer Science and Engineering is ranked
                                                                                                                                                              and eight major hospitals in northeast Ohio.
                                                                                                                                                              NEOUCOM offers doctorate degrees in medicine
                                                outstanding academic research and medical              second in the nation. With more than 365
                                                                                                                                                              and pharmacy.
                                                institutions, and a growing number of innovative       degreed programs, the university’s academic

                                                biomedical companies.                                  research includes biology, nursing, biomedical
                                                                                                       engineering, chemical engineering, polymer
                                                                                                                                                            In addition, nearby Kent State University has active
                                                                                                                                                            research programs in biology, nursing, liquid crystals,
                                                                                                       sciences, and chemistry.                             and psychology. Disciplines within Kent State’s
                                                                                                                                                            Liquid Crystal Institute provide opportunities for
                                                                                                                                                            technology transfer in biomedical-related fields.
The Greater Akron area is                                  OrthoHelix™ Surgical Designs
currently home to numerous                                 OrthoHelix is a leading medical                      ADDITIONAL
innovative companies and research
institutions, including medical
                                                           device company that develops and
                                                           markets a comprehensive line of                          A S S E TS
device manufacturers, biomedical                           innovative orthopaedic implants and
                                                           instruments for use in hand and foot
advanced materials producers, testing                      reconstructive surgery and other
laboratories, diagnostic imaging                           small bone surgery.                                  The Orthopaedic Research                                 Northeastern Ohio Consortium
centers, and consulting and services                                                Institute of Northeastern Ohio                           for Wound Healing Research
companies. Areas of focus include:                                                                              A world-class center of excellence for research and      and Education
                                                           Theken Spine LLC                                     commercialization in skeletal biology, orthopaedics,     Leveraging the historical core competencies of our
  Orthopaedics                                                                                                  and bio-polymers, The Orthopaedic Research
                                                           Theken Spine designs, develops, manufactures,                                                                 regional universities, hospitals, and medical schools,
  Advanced burn and wound care, including                  and distributes a full range of spinal fixation       Institute of Northeastern Ohio (ORINEO) will make        the Northeastern Ohio Consortium for Wound
  tissue engineering                                       products. The company markets its products           its home in Akron’s Biomedical Corridor.                 Healing Research and Education was formed in
  Imaging and diagnostics                                  through a national network of independent            The collective strength of skeletal biology and          2002. The goals of this multi-disciplinary group of
                                                           distributors. Its philosophy is to                   orthopaedic research programs in northeast Ohio          scientists, clinicians, and business professionals
                                                           develop systems with fewer parts                     already rivals any such group in the world. This         are: (1) to understand and solve real-life problems
  Skin hygiene, anti-microbial formulations,               and fewer steps to benefit both                                                                                in wound healing through collaborative research
                                                                                                                new state-of-the art center will unite the unique
  and delivery devices                                     the surgeon and the patient. By                                                                               activities; (2) to further develop translational “bench
                                                                                                                strengths of its collaborators, taking research out
  Biomedical testing                                       using this process, Theken’s systems                 of the “ivory tower” and into patient care delivery      to bedside” commercial opportunities to improve
                                                           may reduce the amount of time                        and private industry through innovative biomedical       patient care; (3) to embrace outreach wound care
                                                           and number of implants currently                                                                              programs to help educate the community at large.
SpineMatrix® Inc.
           ,                                               required by competitive systems in
                                                                                                                products. The Institute will be situated in close
                                                                                                                                                                         Resources include an array of high-tech specialty
                                                                                                                proximity to its partners, which include Akron’s three
SpineMatrix, Inc. is a spinal imaging company              performing the same techniques.                                                                               laboratories, small and large animal model facilities,
                                                                                                                major nationally ranked medical centers – Summa
that developed the CERSR® imaging system for                                                                                                     and clinical locations providing treatment in wound
                                                                                                                Health System, Akron General Medical Center,
evaluating low back physiology related to the origin                                                                                                                     care, burns, and rehabilitative medicine.
                                                                                                                and Akron Children’s Hospital – along with
                    of low back pain (LBP) and injury.
                    CERSR, which is FDA-approved,
                                                           GOJO®                                                The University of Akron and NEOUCOM.

                    aids the physician in accurately       As the inventor of PURELL® Instant Hand Sanitizer,   Research activities will focus on orthopaedic
                    diagnosing the true source of LBP.     GOJO has a 62-year history of leadership in          diseases in children and adults, as well as cutting-
                    It has the potential to significantly   improving well-being through hand hygiene and        edge studies in tissue engineering, and the use of
                    reduce total healthcare costs          healthy skin. GOJO manufactures                      biopolymers for growing bone and cartilage and
                    and dramatically improve patient       and distributes a full line of                       the delivery of drugs. In addition, the Institute will
                    care by directing the LBP patient      products under the PURELL,                           partner with other regional programs located at
to the appropriate diagnostic and therapeutic              GOJO and PROVON® names and                           Case Western Reserve University and the Cleveland
procedures. CERSR is able to differentiate patients        distributes them in a variety of                     Clinic/Lerner Research Institute. The partnership will
who will respond to facet pathology treatment              markets, including automotive,                       represent the largest, most funded and successful
(95% sensitivity) and disc pathology treatment (88%        education, government and                            skeletal biology and orthopaedic research and
sensitivity) from those who will not respond to these      military, healthcare, health and                     commercialization program in the world.
painful, expensive, and invasive procedures.               fitness, foodservice, and food                                        processing and manufacturing.

    TO S U P P O R T Y OU
    The City of Akron has put in place                         Other Programs
                                                               A wide variety of alternative incentives exist to help
    a comprehensive infrastructure of
                                                               new businesses, as well. These include programs
    facilities and experienced personnel                       for training and management, business planning,
    to provide you with the right financial,                    building improvements, relocation, site and building     3   Akron Global
    relocation, market, and business                           location, and other specialized support services.            Business Accelerator
    development support you need                               The Mayor’s Office of Economic Development will
                                                                                                                            A leader in technology commercialization, the
    to succeed.                                                be happy to assist you in creating a benefits package
                                                                                                                            Akron Global Business Accelerator is among the first
                                                               tailored to your specific business needs and goals.
                                                                                                                            and largest centers for entrepreneurial activities in
                                                                                                                            the U.S. Its facility offers more than 20,000 square
1   Economic                                               2   Marketing And Business                                       meters of upscale office, lab, and manufacturing
    Development Programs                                       Development Services                                         space, with state-of-the-art conferencing facilities
    The City of Akron Mayor’s Office of Economic                In addition to funding, we realize you will also need        and information technology services.                    4   Support In Obtaining Funding
    Development is committed to helping businesses             help in the marketing aspects of establishing or                                                                         Your Akron-based team recognizes that securing
                                                                                                                            The Accelerator has established a broad and
    and enterprises strive for success. To provide             expanding your business in the U.S. The market                                                                           the right funding for your business is critical to
                                                                                                                            comprehensive portfolio of business and
    support for relocating business, the City of Akron         environment, growth trends, economic drivers,                                                                            your success. That’s why we have developed
                                                                                                                            technical assistance services that it provides to its
    and the State of Ohio offer a variety of incentives,       customer dynamics, competitive situation, and                                                                            in-depth knowledge and understanding of the many
                                                                                                                            member tenants and local technology companies.
    programs, and resources. When you are                      supply chain factors may be new to you, but                                                                              options available to you and will work with you to
                                                                                                                            These services focus on the specific needs of
    establishing your business in Akron, we will work          understanding them will be critical to your success.                                                                     maximize your chances for obtaining funding. In
                                                                                                                            scalable manufacturing, service, and/or
    to devise a package that will ease your financial                                                                                                                                    collaboration with a network of financial resources,
                                                               To maximize your chances of commercial success,              technology-based companies.
    burdens and provide assistance. Some of these                                                                                                                                       we can assist you with:
    incentives include:                                        we have assembled an outstanding group of                    The program also offers a comprehensive package
                                                               business development professionals with more than            of necessary services to international companies              Reviewing the various funding options available
    Tax Incentives                                             50 years of combined experience. The key marketing           looking to open new markets in North America.                 Establishing contacts with appropriate
    Various tax credit programs exist to encourage             and business development services we offer include           Additionally, the Accelerator has developed strong,           venture capital, seed funds, as well as angel and
    business growth and development. These provide             support in:                                                  collaborative relationships with leading technology           other potential investors
    significant tax savings for companies that create
                                                                 Market research, analysis, and assessment                  incubators in Israel and Germany, and efforts are
    jobs, undertake research and development activities,                                                                                                                                  Accessing state funds available to
                                                                                                                            under way to collaborate with a Chinese incubator.            new businesses
    increase export sales, or make a significant capital          Developing strategic market and business plans
    investment in Ohio. Programs include the Ohio Job                                                                       To help new technology and/or potentially high-
                                                                 Identifying potential strategic partners
    Creation Tax Credit, Research and Development                and customers                                              growth companies find their markets and realize
    Tax Credit, and the Manufacturing Machinery and                                                                         true profit potential, the Accelerator provides the
                                                                 Clinical trials                                            foundation and infrastructure needed.
    Equipment Sales Tax Exemption.
                                                                 Building prototypes
    Grants and Loan Programs
    The State of Ohio offers a number of pre-seed                Understanding regulatory FDA requirements
    and seed grants and loans. In addition, the City             Understanding incentives and
    of Akron and its economic development partners               investment resources
    offer a variety of loan programs for start-ups and
                                                                 Patent searches and registration
    existing small businesses. These loans can be
    used for construction, renovation, expansion, land           Recruiting key personnel
    acquisition, machinery, and equipment.
Mayor Don Plusquellic and the
City of Akron are strongly
committed to helping you grow
your business in Akron and warmly
welcome your inquiries about opportunities that
exist for your company. To speak with the Mayor’s
Office of Economic Development, or to find out
more about the Akron Biomedical Corridor,


                                                    Business Card Slots
                     Mayor’s Office of Economic Development, City of Akron
166 S. High Street, Suite 202   Akron, Ohio 44308 U.S.A.   330-375-2133

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