AP Biology Test Study Guid
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AP Biology Test Study Guide
Science as a Process
Understand how to design a scientific experiment (variables, controls, hypotheses, etc.)
How scientists share data, and use one another’s data
Evolution
Evidence for evolution: fossil record, biogeography, comparative embryology, comparative
anatomy, DNA
Darwin’s Theory
Natural Selection: Disruptive, Stabilizing, Directional;
Genetic Variation and its role in evolution.
Genetic Equilibrium and the Hardy-Weinberg formula (p2 + 2pq + q2 = 1)
Phylogenetic Trees, common ancestry
Causes of Mircoevolution and sources of genetic variation, genetic drift (founders effect,
bottleneck), natural selection, gene flow, mutation, sexual selection (inter/intra), outpreeding,
diploidy, heterozygote advantage,
Patterns of evolution: coevolution, convergent, divergent, parallel
Reproductive isolation: prezygotic vs. postzygotic barriers (habitat, mechanical, behavioral, etc.)
Speciation: Allopatric vs Sympatric
The origin of life on Earth
Ecology
Population Density/Distribution: Types of dispersion, survivorship curves
Carrying capacity, limiting factors (density dependent vs. independent)
Population growth formula and patterns
Ecological niche, resource partitioning, character displacement, realized vs fundamental niche
Competitive Exclusion Principle
Energy flow: food chains vs. webs, producers, consumers, decomposers, scavengers, ecological
pyramids, 10% law
Symbiosis: Commensalism, mutualism, parasitism
Mimicry: Batesian vs. Mullerian
Ecological Succession (Review in Text Book)
Ecosystems
Biogeochemical Cycles Water, Carbon, Nitrogen, Phosphorus,
Chemistry
Types of macromolecules, their structures, and functions: lipids, carbohydrates, nucleic acids,
proteins
Water and its unique properties
Types of bonds
Enzyme structure and function; different types of enzymes, factors that affect enzyme function
Metabolism: catabolic vs. anabolic
Atomic structure
Exergonic vs. endergonic reactions
ATP structure and function
Functional groups; where they are found, what properties do they have
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Cells
Cellular theory
Prokaryotes vs. Eukaryotes
Cell membrane structure: phospholipid bilayer, active transport vs. passive transport, channel
proteins, ion channels, porins, aquaporins, carrier proteins, transport proteins, recognition proteins,
adhesion proteins, receptor proteins, cholesterol, endocytosis, phagocytosis, pinocytosis, exocytosis
Diffusion vs. Osmosis, water potential
Organelles (know the structure and function of the following): cytosol, nucleus, ribosomes, ER,
golgi apparatus, lysosomes, vacuoles, mitochondria, choloroplast, peroxisomes, cytoskeleton,
flagella/cilia, centrioles, cell wals
Cellular communication: gap junctions, plasmodesmata
Cellular Division - Mitosis vs. Meiosis, Regulation of the cell cycle, cancer
Energy
Photosynthesis
o Key molecules (structure and function) - ADP, ATP, NADP+, NADPH, all vital pigments,
balanced equation, where it takes place
o Cyclical vs. Non-Cyclical
o Light-Dependent Reactions: Photpsystems II vs. I, electron transport, electron acceptors,
ETC, Enzymes involved, role of sunlight, What goes in, what comes out?
o Light-Independent Reactions (Calvin Cycle): Know all steps, molecules that go in and come
out, intermediate molecules, molecules involved
o C3 vs C4 photosynthesis; CAM plants, what types of plants use these processes
o Photorespiration
Cellular Respiration
o Redox reactions: oxidation vs. reduction, phosphorylation
o Glycolysis - what goes in/comes out, where does it occur, what are the steps involved
o Krebs Cycle/Citric Acid Cycle - where does it take place, what goes in/comes out, key
molecules (pyruvate, acetyl CoA, Oxaloacetate, NADH, FADH2, ATP
o Aerobic vs. Anaerobic environments: fermentations (alcoholic, lactic acid),
Genetics
Mendels laws (law of segregation, law of independent assortment)
Incomplete dominance, codominance, multiple alleles, epistasis, pleiotropy, polygenic traits, genes
influenced by the environment
Probability calculations, Punnett Squares (monohybrid, dihybrid),
Gene linkage/sex linkage, linkage maps (know how to determine where genes are on a
chromosome), crossing over, crossing over frequencies, X inactivation and Barr Bodies, Non-
disjunction, chromosomal mutations (deletion, duplication, inversion, translocation,
Review of human genetic defects: Down syndrome, Turners, Kleinfelters Syndrome
Pedigrees: be able to read them
DNA/RNA
DNA vs. RNA structure - Phosphate, sugar, bases, base pairing rules, types of bonds between
molecules, Purines vs. Pyrimidines, differences between DNA and RNA, Types of RNA (t,m,r)
DNA organization: Chromatin, Histones, etc.
Genetics of Bacteria and Viruses
DNA Replication
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o 5’ vs. 3’, directionality, anti-parallel, conservative vs. semi-conservative vs. dispersive,
Okazaki fragments
o Enzymes involved in DNA Replication: helicase, DNA polymerase (particularly
directionality), replication forks, primase, primers, DNA Ligase, telomerase/telomers
Protein Synthesis
o Transcription - Initiation, Elongations, Termination (differences in Pro and Eukaryotes),
codons, RNA modification, splicing, Introns, Exons, Poly A tail, 5’ cap, snRNP’s, structure
of tRNA, Aminoacyl-tRNA
o Translation - Initiation, Elongation, Termination, start codon (AUG), ribosomal subunits and
their functions, different sites of tRNA and what occurs there, release factor protein
Gene expression - Operons, repressors, operator, promoter, regulatory genes
DNA Technology: PCR, Gel Electrophoresis, Cloning, Recombinant DNA, Genetic engineering
Plants
Different Phyla of plants - Bryophytes, Pteridiophytes, Gymnosperms, Angiosperms
Adaptations for life on land,
Alternation of generation - dominant spoorphyte or gametophyte of different phylums, life cycles
Structure: Roots, stems, leaves/stomata, vascular tissues, dermal tissues, ground tissues,
perenchyme, collenchyme, sclerenchyme, apical meristems, lateral meristems
Transport- process of water and sugar transport, capillary action, transpiration, bulk flow,
Response to stimuli - Phototropism: hormones involved, processes, cell elongation
Primary vs. Secondary growth, germination, seed structure
Monocots vs. Dicots
Animals
Familiarity of various animal phyla -
Tissue types - Epithelial, Connective, Nervous, Muscle
Thermoregulation - Ectotherms vs. Endotherms
Feedback loops - Negative vs. Positive
Reproduction - Fertilization, Embryonic development (cleavage, morula, blastula, gastrula, etc),
Reproductive anatomy, Gametogenesis, Hormones
Body systems structure and function - Respiratory, Circulatory, Excretory, Digestive System,
Nervous, Muscular System, Immune System (Refer to you text book), Endocrine System
Labs
Refer to Lab Study Guide to review all 12 labs we have covered this year
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