Docstoc

New Hanover Regional Medical Center

Document Sample
New Hanover Regional Medical Center Powered By Docstoc
					                           New Hanover Regional Medical Center
                                         Food and Drug Interactions
                                       Information Sheet for Patients


       Medication/Category                 Effect of Medication                    Food Interaction
                                                Antibiotics
  Clarithromycin (Biaxin, Biaxin XL)      Treats bacterial infections   •   Take Biaxin XL tablets with food

    Erythromycin (EryTab, E.E.S.,         Treats bacterial infections   •   Erythromycin ethylsuccinate,
         Erythrocin,various)                                                erythromycin estolate, and enteric-
                                                                            coated erythromycin may be
                                                                            administered without regard to meals
                                                                        •   Erythromycin base and stearate
                                                                            should be taken on empty stomach
        Metronidazole (Flagyl)            Treats bacterial infections   •   Avoid alcohol and alcohol containing
                                                                            products during and for 3 days after
                                                                            treatment
           Nitrofurantoin                 Treats bacterial infections   •   Take with food
monohydrate/macrocrystals (Macrobid)                                    •   Avoid antacids containing magnesium
                                                                            trisilicate
   Quinolones (ciprofloxacin [Cipro],     Treats bacterial infections   •   Take at least 2 hours before or 6
 levofloxacin [Levaquin], moxifloxacin                                      hours after taking
                [Avelox])                                                   magnesium/aluminum antacids or
                                                                            other products containing calcium,
                                                                            iron, or zinc (at least 4 hours before or
                                                                            8 hours after for Avelox)
                                                                        •   Do not take medication with dairy
                                                                            products or calcium-fortified juices
Tetracyclines (doxycycline [Vibramycin,   Treats bacterial infections   •   Take 1 hour before or 2 hours after
   Doryx, Adoxa, Periostat, various],                                       dairy foods and/or meals
tetracycline [Sumycin], demeclocycline                                  •   Take 2-3 hours before or after
              [Declomycin]                                                  products containing magnesium,
                                                                            aluminum, calcium, iron, or zinc
           Linezolid (Zyvox)              Treats bacterial infections   •   Avoid tyramine containing foods
                                                                            (see Table 2)

                                              Anticoagulants
   Warfarin (Coumadin, Jantoven)           Helps to thin blood and      •   Avoid excessive consumption of
                                               prevent clots                alcohol or “binge” drinking
                                                                        •   Maintain normal, balanced diet with
                                                                            consistent amount of Vitamin K
                                                                        •   Avoid drastic changes in dietary
                                                                            habits, such as eating large amounts
                                                                            of leafy, green vegetables
                                                                        •   See Table 1 for list of foods rich in
                                                                            Vitamin K
                                          Anticonvulsant Agents
         Phenytoin (Dilantin)             Controls/prevents seizures    •   Take with food or milk
                                                                        •   Hold tube feedings for 2 hours before
                                                                            and 2 hours after when administering
                                                                            phenytoin suspension
                                                   Antifungal Agents
    Griseofulvin (Grifulvin-V)               Treats fungal infections     •   Avoid alcohol and alcohol containing
                                                                              products
                                                                          •   Take with high fat meal, if possible
     Itraconazole (Sporanox)                 Treats fungal infections     •   Do not take within 2 hours of antacids
                                                                          •   Take capsules with food
                                                                          •   Take oral solution on empty stomach
      Ketoconazole (Nizoral)                 Treats fungal infections     •   Do not take within 2 hours of antacids
                                                                          •   Avoid alcohol and alcohol containing
                                                                              products

                                                   Antihypertensives
     ACE inhibitors (captopril             Lowers blood pressure, may     •   Consult prescriber or pharmacist before
  [Capoten], enalapril [Vasotec],           protect kidneys if you have       using salt-substitutes containing
lisinopril [Prinivil, Zestril], ramipril              diabetes                potassium
   [Altace], quinapril [ Accupril],
       benazepril [Lotensin])
    ARB’s (valsartan [Diovan],
 irbesartan [Avapro], telmisartan
   [Micardis], losartan [Cozaar],
      candesartan [Atacand],
       olmesartan [Benicar])
                                              Anti-inflammatory Agents
 Corticosteroids (prednisone,              Reduce inflammation, pain,     •   Take with food
dexamethasone, prednisolone)                  fever; various uses
Non-steroidal anti-inflammatory
drugs (ibuprofen [Advil, Motrin],
 naproxen [Aleve, Naprosyn],
           various)
                                                Antineoplastic Agents
    Procarbazine (Matulane)                Used in treatment of various   •   Avoid tyramine containing foods
                                                     cancers                  (see Table 2)
                                                                          •   Avoid alcohol and alcohol containing
                                                                              products
                                               Anti-Parkinson’s Agents
Levodopa/Carbidopa (Sinemet)                  Used in treatment of        •   Avoid high protein diet (>2g/kg)
                                            Parkinson’s, restless legs
                                                   syndrome
                                                 Antipsychotic Agents
   Lithium (Eskalith, Lithobid)                   Various uses            •   Maintain regular diet with salt intake
                                                                          •   Take with food
                                                                          •   Drink 8-10 glasses of water daily
      Ziprasidone (Geodon)                        Various uses            •   Take with food
                                                 Antiretroviral Agents
        Efavirenz (Sustiva)                 Treatment of HIV infection    •   Take on empty stomach, preferably at
                                                                              bedtime

         Abacavir (Ziagen)                  Treatment of HIV infection    •   Avoid alcohol
        Didanosine (Videx)                  Treatment of HIV infection    •   Take on empty stomach
       Atazanavir (Reyataz)                 Treatment of HIV infection    •   Take with food
  Lopinavir/Ritonavir (Kaletra)             Treatment of HIV infection    •   Take oral solution with food
                                             Antiretroviral Agents (cont)
       Nelfinavir (Viracept)                Treatment of HIV infection    •   Take with food
         Ritonavir (Norvir)                 Treatment of HIV infection    •   Take with food
                                              Bisphosphonates
    Alendronate (Fosamax),             Prevention/treatment of       •   Take with full glass of water upon rising
     Risedronate (Actonel)            osteoporosis or other bone         for the day and wait at least 30 minutes
                                              diseases                   before the first food, beverage, or other
                                                                         medication
     Ibandronate (Boniva)              Prevention/treatment of       •   Take with full glass of water upon rising
                                      osteoporosis or other bone         for the day and wait at least 60 minutes
                                              diseases                   before the first food, beverage, or other
                                                                         medication
                                        Immunosuppresant Agents
Mycophenolate mofetil (Cellcept)             Various uses            •   Take on empty stomach
                                  Monoamine Oxidase Inhibitors (MAOI’s)
   Isocarboxazid (Marplan),           Depression, various uses       •   Avoid tyramine containing foods
 Selegiline (Eldepryl, Emsam),                                           (see Table 2)
      Phenelzine (Nardil),
  Tranylcypromine (Parnate)
                                             Thyroid Hormones
   Levothyroxine (Synthroid,            Treats hypothyroidism        •   Take on empty stomach, preferably 30
  Levothroid, Levoxyl, various)                                          minutes to 1 hour before breakfast
                                                Miscellaneous
Nicotinic acid (Niacin, Niaspan)     Treatment of high cholesterol  Take with food
                                                                     •
                                                                    Avoid alcohol and hot beverages or spicy
                                                                     •
                                                                    foods; may increase flushing reaction
    Bisacodyl (Dulcolax)             Treats constipation        • Do not take within 2 hours of milk, dairy
                                                                    products or antacids
    Disulfiram (Antabuse)           Used in treatment of        • Avoid all alcohol and alcohol containing
                                         alcoholism                 products
      Iron supplements              Treats iron deficiency      • Do not take with dairy products or
                                                                    antacids
   • Alprazolam (Xanax)                       • Itraconazole (Sporanox)          • Avoid grapefruit juice
   • Amiodarone (Cordarone,                   • Lovastatin (Mevacor)                with these medications
       Pacerone)                              • Maraviroc (Selzentry)
   • Amlodipine (Norvasc)                     • Methylprednisolone (Medrol)
   • Amprenavir (Agenerase)                   • Midazolam (Versed)
   • Atazanavir (Reyataz)                     • Nicardipine (Cardene)
   • Atorvastatin (Lipitor)                   • Nifedipine (Adalat, Procardia,
   • Buspirone (Buspar)                            various)
   • Carbamazepine (Tegretol,                 • Nimodipine (Nimotop)
       Carbatrol)                             • Quinidine (various)
   • Clarithromycin (Biaxin)                  • Sildenafil (Viagra, Revatio)
   • Cyclosporine (Gengraf, Neoral,           • Simvastatin (Zocor)
       Sandimmune)                            • Sirolimus (Rapamune)
   • Diazepam (Valium)                        • Tacrolimus (Prograf)
   • Diltiazem (Cardizem, various)            • Triazolam (Halcion)
   • Felodipine (Plendil)                     • Verapamil (Calan, various)
   • Fexofenadine (Allegra)                   • Warfarin (Coumadin)
   • Fosamprenavir (Lexiva)
   • Indinavir (Crixivan)
                       Table 1: Foods containing high amounts of Vitamin K
          Alfalfa                                              Green tea
          Asparagus                                            Lentils
          Broccoli                                             Lettuce
          Brussel sprouts                                      Liver
          Cabbage                                              Oats
          Cauliflower                                          Parsley
          Chayote squash                                       Spinach
          Endive                                               Watercress
          Garbonzo beans                                       Canola oil
          Greens (collard, turnip, beet, mustard, kale, chard) Soybean oil
          Green beans
          Green leafy vegetables
          Green scallions



                       Table 2: Foods containing high amounts of tyramine
            Alcoholic beverages       Beer                         Red Wine
                                      Liqueurs                     Sherry Vermouth
                  Cheese              American, processed          Gouda
                                      Blue                         Mozzarella
                                      Brick                        Parmesan
                                      Brie                          Provolone
                                      Cheddar                       Romano
                                                                    Swiss
             Fruits/Vegetables        Avocados                      Prunes
                                      Banana peel                   Raisins
                                      Bean curd, fermented          Sauerkraut
                                      Dried fruit                   Snow pea pods
                                      Fava beans                    Soy bean, fermented
                                      Figs, canned                  Soy sauce
                                      Green beans (Italian)         Soybean paste
                                      Miso soup                     Yeast
                Meats/Fish            Anchovies                      Lunch meats
                                      Bologna                       Meat tenderizer
                                      Caviar                        Pepperoni
                                      Cod                            Salami
                                      Canned meat                    Sausage
                                      Game meats                     Shrimp paste
                                      Herring (pickled/dried)       Smoked fish
                                      Liver (beef/chicken)


1. Facts and Comparisons Online. http://online.factsandcomparisons.com. Last accessed 28 September
   2008.
2. Lexi-Comp Online. http://online.lexi.com/crlsql/servlet/crlonline. Last accessed 28 September 2008.
3. “MUSC Food-Drug Interactions Chart.” www.musc.edu/pharmacyservices/medusepol/Food-drug2006.pdf.

				
DOCUMENT INFO
Shared By:
Categories:
Tags:
Stats:
views:12
posted:8/30/2011
language:English
pages:4