1500 word by yaofenjin



      Lupus is a disease that can become a silent killer. It is not known by many but has an
unlinking cause and effects that is shared by several. Lupus and affects one group in
particular but is not bias it affect every race of people men and women. Bias lupus is not
there are several forms of lupus that affect the human body and the hearts and minds of
those who suffer from the disease along with their family and friends.

      The who, what, when, where, why and how of Lupus. One may ask what lupus is.
Why is it important to me? And how does it affect me? Once you read this article I hope
that you the reader become more aware of what Lupus is and how we as a society must
make the world become more aware of this silent killer disease and help the Lupus suffer
get a cure for this disease.

                                   What is Lupus?

      According to an article written by William C. Shiel Jr “Lupus is an autoimmune
disease characterized by acute and chronic inflammation of various tissues of the body.
Autoimmune diseases are illnesses that occur when the body's tissues are attacked by its
own immune system”. (Shiel 2010) There are no known cures for lupus. Lupus is a disease
that is define very well but still is very complicated to understand.

              Statics on the number of people, race and ages involved

      “Anyone can get lupus, but women are most at risk. Lupus is also more common in
African American, Hispanic, Asian and Native American women. The cause of lupus is not
known.”(Medline Plus 2010) “It is believed that 5 million people throughout the world
have a form of lupus. Our research estimates that at least 1.5 million Americans have
lupus. The actual number may be higher; however, there have been no large-scale studies
to show the actual number of people in the U.S. living with lupus. It is believed that 5
million people throughout the world have a form of lupus.”(Lupus foundation 2010) “The
Lupus Foundation of American and Arthritis Foundation Have suggested that between
500,000 and 1 million Americans have one forms of lupus.” (Wallace p.11)The disease
Lupus affects several people. Lupus affects women, men, children and the elderly. Some
people are severely impacted more than others. Women are affected more severely than
any group of people. Of all the race of women, African American women suffers the most
complications and is affected the severest by Lupus than any race of women or men.
Hispanic and Asian and other minority are the next race of women to be affected by lupus
with harsh complications. Caucasian women are the least affected by the disease. Lupus is
less prominent in men than women. “Many studies have shown that women are about 10
times more likely to have or to develop lupus than men.” (Lupus Site 2010)Lupus affects
men somewhat differently although the symptoms in men are the same as it is for women
who are afflicted with the disease.

                             Symptoms of Lupus

      Lupus is a hard disease to diagnose because some of the symptoms take on
manifestation of other of types medical diagnosis. Physician tends to overlook Lupus until
they see that the symptoms are chronic illness in their patients. People who suffer from
lupus are or maybe afflicted with two or more of the following symptoms swelling in
joints, muscle pain, fever, pain, red rashes, most often on the face (known as the butterfly
rash), chest pain, hair loss, pale or purple fingers or toes, sensitivity to the sun, swelling in
legs or around eyes, mouth ulcers, swollen glands, and fatigue. Lupus can also cause heart
attacks and stoke for individual with the disease.

                      Lupus symptoms in women

      The onset of lupus can be trigger by pregnancy, direct exposure to the sunlight,
infection, and medication. Genetic and the environment are also factors of the onset of
lupus. Lupus onset is found to develop in women childbearing years. The ages for this
group of women ages range from their teen years to mid forties. Although Lupus affects
the body of women and men no two cases are the same. Lupus affects most Lupus suffers
in its own unique way. That is why it is so hard to detect the disease. In women who are
diagnosed with lupus can become a serious and deadly combination. Women who are
afflicted with lupus should seek special medical attention when she becomes pregnant.
These women are consider high risk and needs to be under a physician who handles
patients of their nature. Women with lupus should speak with their physician before
becoming pregnant so they can go over the risks and complication that can possibly can or
may occur with the pregnancy. Among its findings: “Pregnant women with lupus are 20
times more likely to die, and they're four times as apt to develop eclampsia, a serious
condition often accompanied by seizures.” (Mann 2006) “Women with lupus need to be
followed very carefully by a rheumatologist and a high-risk obstetrician, but the majority
if women with lupus can and will have a successful pregnancy and deliver a healthy baby,”
says researcher Megan Clowse, MD. (Mann 2006)

                     Lupus symptoms in men

      Men shares similar symptom as women do with lupus such as stress. Stress in men
who are inflicted with lupus is a hard problem for most to deal with. Men handle the stress
of having lupus differently than women. The affect of lupus is viewed by some men who
suffer from the disease as being embarrassing. Men do not want to share their emotions
with their family and friend because they feel that they will be down look on since lupus is
known as a women disease. Many men who suffer from the disease tend to worry about
their ability to be an effective male role model in their family setting because lupus
sometimes renders their abilities to work and perform certain hobbies. They also have
some concerns about their sexual needs and performances. Men who are afflicted with
lupus also have difficulties dealing with the affects that lupus cause on their outer being.
Because lupus causes hair loss, skin break down (rashes), and weight loss and or gain set
the mode for some men to having low self esteem. The more component of lupus that
affects the men who have lupus the harder for them to cope because yet men do have the
disease. It is for them because of their masculinity.

                            Types of Lupus

      There are four different types of Lupus. The different types of Lupus are Systemic
Lupus Erythematosus, Drug-Induced Lupus, Discoid Lupus Erythematosus and neonatal
      Systemic Lupus Erythematosus also called SLE is the Lupus that is affected by the
most people who are afflicted with lupus. It is the most common form of the disease. SLE
affects the body causing it to fight against the healthy cells. It causes damages against the
organs in the body. The organs that are affected are the lungs, heart, joints, and the
kidneys. It also affects the joints, skin and the blood vessels. It is a very painful disease.
Individual afflicted with lupus can have mild, moderate or severe pain when the lupus
onsets. Systemic Lupus Erythematosus can become a chronic or non-chronic.

      The second type of Lupus is called a Drug-Induced Lupus. A Drug-Induced Lupus is a
condition that takes on the manifestation of Lupus but is cause by drugs that makes
appear like lupus. It can occur months to years after being on certain medication. Drug-
Induced Lupus will discontinue after the person stop using the medication causing this
type of lupus. This will take up to two days up to a month.

The third type of Lupus is called Discoid Lupus Erythematosus. Discoid Lupus
Erythematosus is a type of Lupus that affects the skin. The rash affects the face, ears and
scalp. “According to an article in American Osteopathic College of Dermatology Discoid
lupus erythematosus (DLE) is a chronic skin condition of sores with inflammation and
scarring favoring the face, ears, and scalp and at times on other body areas. These lesions
develop as a red, inflamed patch with a scaling and crusty appearance. The center areas
may appear lighter in color with a rim darker than the normal skin.”(Discoid 2010)

      The fourth and last type of Lupus is called neonatal Lupus. Neonatal Lupus is
somewhat rare but skill oh so real. It affects the newborn when born by causing problems
with their skin, blood and sometimes their hearts. It happens while in utero when the
mother’s autoantibodies are passed to the newborn. It is a temporary form of Lupus
although the condition that maybe caused may become permanent due to the
autoantibodies exchange.

      “Systemic lupus accounts for approximately 70 percent of all cases of lupus. In
approximately half of these cases, a major organ, such as the heart, lungs, kidneys or brain,
will be affected. Cutaneous lupus (affecting only the skin) accounts for approximately 10
percent of all lupus cases. Drug-induced lupus accounts for about 10 percent of all lupus
cases and is caused by high doses of certain medications. The symptoms of drug-induced
lupus are similar to systemic lupus; however, symptoms usually subside when the
medications are discontinued.” (Lupus Foundation of America 2010)

                      Lupus vs. Insurance

       It is hard for a person with lupus to get insurance. Most insurance company
considers lupus patient high risk. If the insurance company do insure the patient the cost
is very high for an individual person trying to get medical insurance on the own. Person
diagnose with lupus that get insurance through their job may be asked by the insurance
company to show proof of medical insurance coverage the previous year. The individual
maybe told that the insurance company will cover them the next work year. Most
insurance company also may not offer life insurance to individuals who have been
diagnosed with lupus. If the insurance company offers insurance for individuals with lupus
it most likely is very costly. Doctors’ sometimes try to intervene in this matter. “Moreover,
many physicians do not list lupus as a diagnosis on an insurance form because it might
result in the policy being canceled or the illness being disclosed to fellow employees”
(Wallace p.11)

                              Lupus Doctors

Lupus affects the body and it organs in several ways. There is a need for different doctors
to treat the people who are afflicted with lupus. The doctors who may become an important
element of a lupus patient are dermatologist, cardiologist, nephrologists, neurologist,
perinatologist and a rheumatologist. The first doctor is a dermatologist is a doctor that
takes care of the lupus patient skin, mouth and hair loss. The second doctor involve in
caring for a person afflicted with lupus is a cardiologist. A cardiologist is a doctor that deals
with heart problem in patient whose heart is not functioning properly. The third doctor is a
nephrologists. A nephrologist is a doctor that specializes in the renal system. The fourth
doctor is a neurologist. A neurologist is a doctor who specializes in the nervous system
within the body. The fifth doctor is a perinatologist. A perinatologist is a doctor who
specialty is working with female lupus patient who become pregnant and are consider
being high risk. The perinatologist usually is call to treat lupus patient. The last doctor is a
    rheumatologist. A rheumatologist is the doctor that will help combat and address problems
    with the joints and muscle in a patient with such complication.


           “According to an article written by Thomas H. Maugh II, of theLos Angeles Times. On
    November 17, 2010 A Food and Drug Administration advisory panel Tuesday voted 13-2 to
    recommend approval of Benlysta, the first new drug to treat lupus in more than half a
    century. The FDA has set Dec. 9 as the date to make a final decision on the drug. It doesn't
    have to follow the advice of its advisory panels, but it generally does.

           Benlysta is not a wonder drug that will provide relief to everybody with the
    debilitating disease, but it may provide benefits for some and allow them to taper off
    existing drugs, which have powerful side effects that some think are nearly as bad as the
    disease itself.”(Maugh 2010)

    “According to the Lupus Foundation Of America every advance in the understanding of a
    disease such as lupus -- its causes, its effects on the body, the development of new drugs
    and treatments -- is based on research.

    The Center for Clinical Trials Education provides:

          a comprehensive search tool for clinical trial information
          points to consider before participating in a clinical trial
          a guide to clinical research terms
          the latest news on lupus and clinical research
          resources for additional information and support

    According to Center Watch, 94% of people recognize the importance of participating in
    clinical research in order to assist in the advancement of medical science. Yet 75% of the
    general public state that they have little to no knowledge about the clinical research
    enterprise and the participation process.”(Lupus 2010)

       Lupus affects many people all over the world. It is all ways go to have some type of
knowledge on the subject of lupus. Not knowing is worse than ignoring it. There are several
lupus quizzes online to help you get a general understanding of all the information given in
this paper. In power yourself with knowledge and pass it on to all your peers in efforts to
being some noise to this silent killer called lupus. If all of the world report to other on this
silent killer disease than it will no longer be silent and it will be expose and maybe there
may a cure for it and save the lives of more individual afflicted with lupus.

Works Cited

  1. Lupus Incidence Within the Community, The Lupus Site, October 4, 2010 Retrieved
      from http://www.uklupus.co.uk/fact1.html
  2. August 24, 2010.Lupus,MedlinePlus.Retrieved (2010) from
  3. Lupus Foundation of America, Statistics on Lupus (2010) Retrieved from
  4. Lupus Foundation of America, Center for Clinical Trials Education (2010) Retrieved
  5. Discoid Lupus Erythematosus, American Osteopathic College of Dermatology (2010)
      Retrieved from
  6. Maugh, Thomas H. II, FDA advisory panel approves new drug for lupus, Benlysta
      (2010) http://articles.latimes.com/2010/nov/17/news/la-heb-lupus-drug-
7. What is Lupus? The Lupus Foundation of America (2010) Retrieved from
8. Mann, Denise (Nov 14,2006) Risks For Pregnant Women with Lupus, Lupus Health
    Center Retrieved from lupus http://lupus.webmd.com/news/20061115/women-
9. Wallace, Daniel J (2009). The Lupus Book: A Guide for Patient and Their Families
10. WILLIAM C. SHIEL JR., MD, FACP, FACR.Systemic Lupus Erythematosus
   (SLE or Lupus).Medicine.net.com (2010)Retrieved from

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