PowerPoint-presentation

Document Sample
PowerPoint-presentation Powered By Docstoc
					                   Folate (F)
DNA                     NADPH + H+


              Dihydrofolate (FH2)                                Methionine
dTMP                                                             ATP
                                                                       Methionine
                         NADPH +   H+
                                                                       adenosyltransferase
                                                           PPi + Pi
 Thymidylate
 synthetase  Tetrahydrofolate (FH4)                        S-Adenosylmethionine
              Serine                                       Acceptor
                                                                       Methyl transferase
             Glycine                                    Methylated
dUMP                                    Methionine
                                                          acceptor
                                        synthase,
             5,10-Methylene FH4          MSR and         S-Adenosylhomocysteine
                                        vitamin B12
                MTHFR
                                                                              Adenosine

                 5-Methyl FH4                                   Homocysteine
                                                             Serine
                                                                       Cystathionine
                                                                       b-synthase

                                                               Cystathionine

                                                                       Cystathionase


                                                      Cysteine + NH3 + a-Ketobutyrate