THE AESTHETIC SIDE OF MEDICINE VOL. 1 No. 2 November 2007
Dr. Alain Gondinet
"The Science of Meso-Pain"
Upcoming Stemcell Workshop
By Prof. Dr. Leow Chong Ngan
Works Even Better
MTS Roller System
Prof. DR. Dr. Walujo Soerjodibroto, SpGK
Mesotherapy as a Part of
Obesity Nutrition Therapy Priscilla Yong
Aesthetic Medicine Training IMMA (Indonesian Medical Mesotherapy Association) is the
first Mesotherapy Education Center
in Indonesia. IMMA Training present to gives alternative on
skin, face, and body health and beauty care
Why IMMA Training?
» Accredited by Lembaga Nasional (DIKMENTI)
» Professional Trainer & Up-to-date Curricullum
» Hands on (direct action to the patient)
» Comfortable training & practice room
» Modern and high technology beauty products and tools
» Basic Mesotherapy
» Advanced Mesotherapy
» Chemical Peeling with Easy TCA
» Botulinum Toxin Type A-Mesobotox & Botox
» Aptos Model
Cosmetic training by Medica Persada
Beauty and spa training by IMMA
Do you need highly skilled well-trained beauty theraphist staffs?
Medica Persada as Indonesian aesthetic training center pioneer
would like to hold an education program about how to choose safe
and high quality cosmetic products and also how to use it with an
update style. Our mission is to improve beauty and make up
knowledge and skill so that Indonesian women can be seen as
healthy and stylish ladies. We also would like to give knowledge
about safe and healthy cosmetics since a lot of products in market
contain toxic agents that can harm people.
Supported by professional teachers with education background,
Medica Persada Aesthetic Training Center is optimist that this
training will be useful for all who concern about appearance and
We also would like to hold beauty training for beauty care provider.
Since there are many misperceptions and mistakes done in beauty
services held by nonmedical workers, IMMA will hold beauty and
medical spa training starting December 2008. This training is For more information
conducted for spa or beauty salon owners or practitioners, nurses, & registration please contact:
physiotherapists and pharmacists. After 1 week training,
Mrs. Ati & Mr. Eko
all participant can practice the right way to perform many beauty IMMA (Indonesian Medical Mesotherapy Association)
services. Enhancement of the service quality will not only improve Jl. Kramat VI/13, Jakarta Pusat 10430, Indonesia
their ability, but also their customer’s satisfaction. Tel: +62-21-390-9333/7077-1331/391-7373
THE AESTHETIC SIDE OF MEDICINE
Dr. Ratna H. Purwoko, Sp.KK
Editor in Chief
Dr. Reza Y. Purwoko, Sp.KK
From The Editor WHO’S INSIDE
At first, in this wonderful opportunity I would like to say Taqoballahu minna wa minkum
Minal Aidzin walfaidzin, Happy Ied Mubarak to all readers of Aesthedica. EDITOR
Dr. Elizabeth Yasmine
Dr. Mirna Praptini Nurasri
In this second edition of Aesthedica, the Aesthetic Side of Medicine Magazine, the Man-
agement and Editorial Board wish to you our sincere hope that you will find all useful REPORTER
sources of information and innovation about Aesthetic Medicine in English.
ART, DESIGN & PRODUCTION
This issue contains reports from interviews with Aptos Trainers, Aesthetic Specialists, Aiko Urfia Rakhmi
and Aesthetic Models and as an added value for readers; we present a report about
mesolipo by Prof. Walujo Soerdjodibroto throughout his years of experiences. ADVERTISING AND MARKETING
But off course in its infancy a magazine is normally far from being perfect, and we real- Abdul Ruhadi
ize that Aethedica is not an exception. Ade Nurbaeti
Hery Agus Santoso
Even thought we really welcome any constructive advices and we invite you hereby to Lucia Trisnawati
be a contributor for articles or any publication on exclusive issue and ideas related to Resti
May the Almighty God bless this modest yet useful endeavor which provide a practical Nurnarisasi
vehicle for Beauty Skin Centers, Physicians, Aesthetic Specialist and all stakeholders in
SALES AND DISTRIBUTION
Aesthetic Medicine in Indonesia and beyond share their innovations and passion to all Indar
Aesthetic Community. Triyanto
PRINTED AND PUBLISHED BY:
Dr. Ratna H. Purwoko, Sp.KK IMMA
Kramat VI No.13
Jakarta Pusat 10430
Tel: (+62)21 70771331
Fax: (+62)21 3909333, (+62)21 3917373
Account No. 6340 169 831
a.n. Mery Tay
Aesthedica November 2007
05 Beautiful lady by nature, healthy woman by lifestyle.
We proudly introduce you to Mrs. Priscilla Yong.
06 Penetrates deeper, works even microneedle system.
Another breakthrough is the
People had made pricky device to create multiple
trauma on skin so that applied drug can penetrate
12 Dr. Alain of mesogel and pioneer in mesotherapy for
15 Alopeciahave shown that people underwent hair loss
can experience psychological stress and disturb their
perception as self and weaken confidence.
25 Mesolipo can be used from the beginning if the
problem was only overweight and not obesity.
ask the reference
17 Acthyderm allows a simple, rapid, and effective
transdermal therapy, providing surprising results
without surgery or injections.
34 Aesthetic Seminar, Cosmobeaute Indonesia.
GET YOUR OWN DEVICE NOW! 28
MONTHLY HIGHLIGHT 35
Pri scill a Y on g:
Ca n you gu ess my age?
B eautiful lady by nature, healthy woman
We proudly introduce you to Mrs. Priscilla
First time Aesthedica met this beautiful
lady, we are so amazed by
her hospitality. With her gorgeous smile
, she gave us a slight look at a
dimple on her right cheek.
• Good afternoon, Mrs. Yong. How are
Oh, never been better! Please call me Prisc
• How do you keep your body figure, Pris?
Just like any other woman, a proper diet
• And how do you do your diet?
To be slim and fit like me, you don't have
yourself with eating almost nothing. I still
enough carbohydrate. Well, it's not every
day that I eat rice. Sometime I eat bread
or noodle, in a small portion, of course.
give s me
I also prefer fish than red meat. I eat me sotreat me nt
a lot of fruits, vegetable, and also
some vitamins. Do you know how to
and MTS rolle r, also
consume vegetable in large portions? give s me slim min g
You can make vegetable and fruit juice
with an extractor! My favourite is cai
crea m for my With her healthy life style and her cons
taking care of her skin, no wonder she
sim, pineapple, and watermelon. And one tu mm y." woman in her late twen
looked like a
more important thing. No snacking! That' ties. We were so surprised when
s she showed us pictures of her daughters
the key of any successful diet, . Looking at her,
nobody would ever guess that she alrea
I guess. dy has 2 children,
These are some pictures of my sweet daug
• What about your skin treatment? hters. Here is Givela
(14) and Ghania (11). Ghania often sings
For my face, I give trust to dr. Reza. He in some public occa-
gave me mesotreatment sions. Maybe she will follow her moth
and MTS roller. Indeed, many of my friend er's footsteps to be a
s told me that my skin public figure one day.
glows brighter since dr.Reza handled me.
Mm.. it's not for promo-
tion that I speak like this. You can ask my
friends yourself. He also Well, keep up the good work, Priscilla. Your
gives me slimming cream for my tumm healthy lifestyle is a
y. Sometime if I felt like very good example for Aesthedica reade
I eat too much, I put stagen overnight. rs. As an actress, pho-
With so, I wake up with a tomodel, property dealer, and also a moth
fresher feeling in my tummy. er of two, you are
truly gorgeous! ( YA S M I N E ) +
Works Even Better
Dr. Elizabeth Yasmine
M any transdermal drugs are in- then, many injection methods are used, such as epidermic, multi
pricking, and point per point. Each has its own advantages and
vented to give certain results. indications.2
But behind those drug inventions,
many equipment and methods are Another evolution in me-
sotherapy is the micro-me-
also invented to give way to drugs sotherapy. Unlike general
so that they can penetrate deeper, practice of mesotherapy
hence work even better. that uses 4 mm-length nee-
dle into the deep layer of
the epidermis, micro-me-
Transdermal drug delivery is based on the absorption of drug sotherapy uses an ultra
into the skin after topical application. But the application of med- thin needle of 23 G x 2 mm
ical or cosmetic products on skin is always affected by the stra- and allows injection in the
tum corneum which acts as barrier and constitutes a strong elec- superficial layer of the der-
trical impedance. However, the lipophilic nature of the stratum mis (papillary layer). This
corneum in particular mean that the useful transport of charged technique is able to reduce
and/or highly polar drugs requires an effective enhancement the undesirable effects and
risks of the traditional me-
sotherapy such as, break-
Transdermal delivery system not only have to provide drug to ing the small veins and
the skin under stable conditions and in a form convenient to pa- small arteries, damage of
tient, but also serve to locally increase the permeability of skin to the deep dermis, and pain-
larger, charged, or hydrophilic drug molecules while minimizing ful injections due to super-
irritation.1 ficial nerves.2
The most common method is to spread cream on the skin. De- The development of mesogun was a major breakthrough to re-
pending on the substance, the penetration is very different. Un- duce the pain and to inject drugs at the same depth. Many me-
fortunately, most of the cosmetic substances cannot penetrate soguns are now available with many helpful features, such as
the skin.2 skin stabilizer, deep injections, no leakage between injections,
and many more.2
Mesotherapy was once developed by Michael Pistor by admit-
ting drugs to epidermis with needles. It goes directly to the tar- Another breakthrough was the microneedle system. People
get cells, hence works better that just topical application. Since had made pricky device to create multiple trauma on skin so
that drug applied can penetrate deeper. The first generation of collagen induction.2,4 Using MTS, the epidermis remain intact
this device has uneven needle length and uneven distance be- because the microprick channels created by the device will be
tween needles. And now, Microneedle Therapy System (MTS) is closed within hours. This is an advantage of the MTS, that we do
available with microneedle not need to damage epidermis to induce collagen production.
roller. Each roller has 200 These channels also act as new transcelular route for drug to
micro needles and this go through, hence it will improve the penetration of therapeutic
system offers different active ingredients applied.2,3,5
needle length for different
purposes. For home care, A clinical studies conducted in South Korea have shown that
it is advised to use 0,2 mm MTS rollers are more effective in increasing the thickness of the
while professionals use skin than IPL and just as effective as ablative treatments, such as
0,5 mm to 2,0 mm.2,3 chemical peel, dermabrasion, laser resurfacing, and non abla-
tive machine based treatments such as CO2 laser, Fraxel, and
After drug have been ap- Thermage.6
plied, the device should
be rolled horizontal, ver- “Doctors may try the roller on half their face, or their hand. They
tical, and diagonal. The ”
will see the difference with the other half then. Purwoko said,
end points are erythema very convinced and satisfied with the result he experienced
and small puntate bleed- himself. Purwoko does not feel the need to invest on expensive
ing. The bleeding are so machine such as laser or others high-cost devices. Instead, he
small, it will stop without prefers to stock MTS Roller which gives the same or even better
any effort, said dr. Reza Y. results but has a lower price. Hence, the cost bore by patients is
Purwoko, Sp.KK. also lower.
MTS roller is a high qual-
ity roller, which has sharp
and rustproof needles, has uniform length thickness and spaces No Needles Needed
apart, and the needles will not come off. Micro channels created Some patients afraid of the painful procedure of mesotherapy,
by the roller have equal sizes and depths.2,3 This is why USA although mesogun was created to minimize the pain. Transder-
Food Drug Administration (FDA) have approved MTS roller in- mal delivery systems can be enhanced with occlusive adhesive
stead of other rollers. Some of other rollers are actually get the plaster. People might be already familiar with nicotine or hor-
approval from their local countries such as Korean FDA, China monal patch.
Not quite satisfied with the passive transport as plaster, people
The micro injury created by the roller will promote healing and try to invent the active transport system using ultrasonic or ion-
U sing MTS, the epidermis remain intact because the microprick channels
created by the device will be closed within hours. This is an advantage
of the MTS, that we do not need to damage epidermis to induce collagen
ideal driving force that favors the transdermal passage of the
marked substance. Hence, mesoporation is an effective method
for transdermal ionized and neutral drugs.1
The electroporation impulses lead to a temporary reorgani-
zation of the cellular membrane allowing the creation of new
channels through cells and the cellular membrane,the Elec-
tropores, which facilitates the flow of water- and non water-sol-
uble molecules. Due to the shape of the electropores created by
Acthyderm, neutral and undissociated molecules can also be
transported into the cells.2 ( YA S M I N E & M I R N A ) +
tophoresis. Iontophoresis enhances drug delivery by electrore- References
pulsion, electro-osmosis, and electrically induced skin perme- 1. Amitrano C, Cappelletti R, Torre R. New trends in drug
ability changes. But the depth of drug penetration has not been deliver y systems: mesoporation, a novel technique.
able to compete mesotherapy injections.3 American Journal of Mesotherapy, 2006.
2. Pur woko RY. Increasing Topical Product Penetration.
Then people used electroporation, a stem method from ionto- Pertemuan Ilmiah Tahunan Perkumpulan Dokter Spesialis
phoresis. Unlike iontophoresis, electroporation can channel-in Kulit dan Kelamin XI Surabaya. 2007.
positive, negative, and neutral molecules by creating new chan- 3. Microneedle therapy system. Cited from http://www.
nels through the cells and the cell-membrane.1,2 microneedle.com on October 10th 2007.
A research was conducted to compare the penetration of radio- 4. Greco JF. Micro needling and injecting platelet rich plasma
active-labelled substances by using iontophoresis and mesopo- to enhance collagen synthesis and skin tightening. 2006
ration by Achtyderm. The research concluded that iontophore- 5. Joon KB. Microneedle therapy system. 2006
sis is minimally efficient in transdermal transportation of the 6. Moon HS, Kim SE, Ko DS, Lee AY. Collagen induction
marked substance administered. Mesoporation delivers 99% of therapy in mouse (IPL vs micro-needling). 2006
mesotherapy formulation at the depth of centimeter and ap- 7. Schied G. A different kind of mesotherapy. American
proximately 65% at the depth of 6 centimeters, while traditional Journal of Mesotherapy, 2005.
iontophoresis delivers only about 10% of the product at the
8. Dobradin A. Mesoporation – a new addition to
depth of 1 cm.1,8 mesotherapy and no-needle drug deliver y. American
Journal of Mesotherapy, 2007.
This result may be related to the lipophilic nature of the stra-
tum corneum which is an electrical impedance. Mesoporation
improves migration of the radioactive compound under the
effect of the electrical field and the electric roll-on creates an
SKIN FRIENDLY, FASTER RECUPERATION, COST-EFFECTIVE
There are THREE major advantages
for using MTS Roller:
MTS Rollers are revolutionary. They do the same job that 100
lasers and other ablative methods by increasing into the skin
the production of collagen with minimal damage to the
protective layer of the skin.
MTS Rollers are effective. In fact, just as effective 60
as lasers, IPL, Thermage and other ‘machine-based’
Up to 3000% of
treatments, but at a fraction of the cost
to practitioners and patients.
MTS Rollers are safe. “Non-surgical and non- 20
ablative” means more ‘forgiving’ and skin-friendly
treatments. Patients experience little or no pain, Mosturizer
downtime, and risk for complications. 0
0.03-1% 1-5% 3-20% 75-85%
Burning Scar Treatment
TYPE PRODUCT LENGTH METHODS
Before Personal Use CR2 0.2mm Skin restoration
CR3 0.3mm Improve Alopecia
CR3 Drug delivery
Clinical Use CR5 0.5mm Skin Whitening,
Improve skin pigmentation,
Improve wrinkle (eye area),
After 2 weeks
CR5 Drug Delivery
Medical Use CR10 1.0mm Improve wrinkle,
CR20 2.0mm Collagen induction,
CR30 3.0mm Improve skin scar,
After 1 month Cellulite treatment,
Alopecia Face firming,
Face body lifting
Before After 6 weeks
1. Clinical Study: MTS (Microneedle Therapy System), 5-Month Study; Dr KB Joon, Department of Dermatology,
Acne Treatment Dongguk University, S. Korea (2006).
2. Collagen Induction Therapy Comparison (IPL vs Micro-Needling); Drs HS Moon, SE Kim, DS Ko, AY Lee, Dep. of
Dermatology, Eulji University School of Medicine and Dongguk University, S. Korea (2006).
3. Product Comparison Study (MTS Roller vs Dermaroller); manufacturer’s shelf-life and usage study, including
known references on materials and usage.
PRACTISING MTS ROLLER
As simple as that!
Dr. Mirna Nurasri Praptini
A lthough full sets of MTS Roller can only be bought by
medical personnels and certified therapists, any profes-
sional beauty practitioners can in fact learn how to use MTS
used if you want to enhance the drug penetration. Cleanse the
treated area with a sponge after anesthesia is confirmed. Topical
anesthetics that usually used are those that contain benzocaine
Roller in only two hours. Patients can also bring their personal (20%), lidocaine (4%), tetracaine (2%) and pramoxine HCI (1%).
MTS Roller home and use it by themselves after being taught
by their therapists. By using the equipment at home, the cost of The next step is to 3) apply solution #1. Clinical studies conduct-
therapy will be lower and the result will be better and sooner to ed by Dr. B.J. Kim showed that ‘double’ applications increase
be seen. The best result can be seen after 6 months of only one efficacy of the treatment modality. Step 4) is using the roller.
per month visit to the clinic. The treatment area should be divided into subdivisions before
applying the treatment roller (CR5, CR10, CR20 and/or CR30)
To treat one patient it is needed a wash, one treatment roller with the similar pressure on the skin, vertically, horizontally and
(MTS Roller model CR5 and up), a topical anesthetic (e.g., diagonally. Don’t change course while rolling and don’t apply
benzocaine, lidocaine, tetracaine, pramoxine HCI), two topical pressure too much.
aesthetical ingredients(e.g., peptide, retinol, collagen), a sooth-
ing mask, moisturizer and sun block (SPF 30). To applicate the
anesthetic, clinicians may also use another model of MTS Roller
which is model CR2. Other options include ultrasound, Ionto,
topical skin nutrients, and microdermabrasion to smooth the Figure 2. Roller Direction
skin and achieve better result.
After that we 5) apply solution #2 as much as it takes to the
Procedure to Use MTS Roller for Clinicians treated area. Ultrasound can be administer to the treated area
MTS Roller application consists of 7 steps that take approxi- to enhance serum absorption. The step after that is 6) relaxation
mately 20-30 minutes. when we apply a mask pack or other soothing application for
relaxation. The last step is 7) postcare or completion. In this step
we can give nutrition, moisturizer and sunblocks.
Cleaning MTS Roller
MTS Roller can stand multiple contacts with “cold sterilization”
agents such as germicides (phenol, ethyl alcohol), Cidex™ (glu-
Figure 1. Steps using MTS Roller for Clinicians taraldehyde), and common ultrasound cleaning devices. Rinse
rollers thoroughly and return to its protective case after drying.
The first step is 1) preparation where we thoroughly cleanse the
application area then 2) applying local anesthetic as needed – Storing MTS Roller
recommended for CR5, CR10, CR20, and CR30. The CR2 can be The MTS Roller came with a protective case and sealed in a ster-
ilized pouch. After each use (and cleaning) return the MTS Roller ment area(s) into subdivisions, for instance the forehead, nose,
back to the protective case. Always treat the MTS Roller gently cheeks, mouth, and neck area. Apply MTS-Roller with the same
and avoid any contact with hard objects or surfaces. All rollers amount of pressure on the skin. Roll the same areas vertically,
that have been dropped should be discarded and keep rollers horizontally and diagonally.
out of reach of children.
Step 3) is active ingredients application such as peptides or vita-
Indications min A, C, E and betacarotene. Allow a few minutes for the appli-
Basically MTS Roller can be used with any kinds of serum or cations to be absorbed to firm and tone skin. Step 4) Protection,
cream to enhance the penetration of ingredients but MTS come additional nutrition, moisturizing and sunblocks management is
with its own lines of therapy. Various clinical studies have been recommended. The last step is to 5) clean roller and return it to
conducted to treat scars, wrinkles, large pores, hyperpigmenta- its protective case.
tion, stretchmarks and alopecia.
The treatment should be repeated between two to seven times
Contraindications a week. Should the skin feel sensitive after a treatment, it is ad-
Do not use MTS Roller on irritated skin, infected skin, fungal skin vised not to use the instrument again until the skin feels com-
infections, active acne, rosacea, eczema, psoriasis, severe solar fortable. The tiny holes, formed from the use of the treatment,
keratosis, raised moles and/or warts, and/or any open wounds in the epidermal layer seal naturally within a day. The more fre-
or sores. quent the treatment, the better the result. At the beginning it is
better to use the MTS Roller at bedtime every second day until
Side Effects skin becomes accustomed to the roller. After the second or third
No side effects from using MTS Roller when used as directed week you may roll daily if you think it is necessary. Do not use
under the advice or supervision of a trained skin care profes- the MTS Roller vigorously or more than once daily unless pre-
sional are shown by clinical studies. The recorded side effects scribed by a professional skin care specialist.
are infections when were done in nonsterile places. Serums,
creams and/or any other cosmeceutical topical can only be used Cleaning MTS Roller at Home
under supervision of a trained skin care professional. You may use denture tablets dissolved in water to clean the
MTS Roller. Denture tables are enzyme cleansers and enzymes
Procedure to Use MTS Roller at Home take off fat as well as reduce bacteria. While not as effective,
To achieve better and faster result, it is recommended that the alcohol (isopropyl) can also be used. Consult a pharmacist for
patient use a personal MTS Roller model CR2 or CR3 for applica- the best advice for a sterilization solution. Open the cleaning
tion of vitamin solutions and moisturizer with sun block proper- tray and place the white cleaning pad in the larger half of the
ties. Please remember to give proper instruction to patients on tray. Fill the cleaning tray with sterilization solution and roll the
how to use their personal roller. Usually the treatment time take roller into the pad with medium pressure. Leave the MTS Roller
time from 5 to 10 minutes depending on the size of the area, in the cleaning solution for about 15 to 30 minutes – ensure that
given two to three times a week. Advise the patient to stop and the roller drum is constantly wet with the cleaning solution. Af-
call if they experience sudden and prolonged irritation in the ter cleaning, rinse with tap water and return the roller to the
treatment area. protective case and allow it to air dry. Replace the case lid until
the next use. q
Tips from the expert:
When applying anesthetic cream before using the
roller, for example BLT mesomedica anesthetic cream,
Figure 3. Steps using MTS Roller at Home don’t forget to cover the skin with thin plastics for 15
minutes to maximize cream penetration. Patient will
feel less pain and more comfortable during proce-
Step 1) is for cleansing and boosting. Firstly clean the skin, rinse
dures. And never forget to inform patient about the
thoroughly and dry with towel, after that applying topical so- possible side effect of thickness sensation and non-
lution such as vitamin C or MTS VItaPep Serum for the maxi- sensoric of the lips. (Dr. Reza Y. Purwoko)
mum MTS effect. The next step is 2) MTS Roller, divide the treat-
Dream of A
Alain Gondinet, MD
O n October 27th 2007, our correspondent Mirna Nurasri had
an opportunity to interview a world renowned doctor in
mesotherapy, doctor Alain Gondinet, in the middle of his visit to
When you meet a doctor, in a minute you (the doctor) can know
everything about the patient because he (patient) wants to tell
the doctor everything. This is the only job in the world that make
Jakarta. In this rare piece their conversation ranging from book it possible for people to trust you. And when I go around the
publication plan, Indonesian attentive doctors to his prediction world I meet many people and I have many good friends along
of cancer among urban citizen. the way. It is very interesting. And the second reason that in this
world you have goals. My goal, other than to succeed, is I also
What do you still want to reach in your career? want to transmit knowledge. And in this profession I can share
I want to introduce antioxidative mesotherapy to the world be- my knowledge to many people.
cause it has not only aesthetic purpose but also in reducing pain
in rheumatology. with specifis coctails of medicine, vitamin and Many cosmetic practitioners and patients are overdoing their
organic silicon. I also want to find an antioxidative society and treatments, do you have something to say about this?
to teach more students. When we do treatment, laser, etc, we have to think about the
consequences of medical device, think about oxidative stress
What is your best experience with a patient? these treatments produce because free radicals are the cause
It is when a long time a go, a patient came with an ambulance of many diseases. After doing a stressful therapy you have to
having a kind of sciatica and came home with his feet. give an antioxidative therapy, with antioxidative mesotherapy
and antioxidants. And the other thing is to train the mentality of
And the worst? doctors that our body needs natural treatment.
To do something wrong to patients, to misdiagnose a patient.
What beauty means to you as a doctor who practice in beauty
Do you think the pain management with mesotherapy is al- business?
ready the best pain (rheumatological I think the thing is to say no when
related) therapy available? the treatment is too much. Asia
Mesotherapy is very efficient in spe- and Europe have different con-
cific pain such as in rheumatology but cept of beauty and doctors have
of course it is not efficient for cancer to know when they’re giving
pain. And yes, I think mesotherapy in too much treatments to patients
rheumatological pain is one of the best and they have to think about the
therapy. Also because I’ve practiced it health of the patients. In Asia peo-
myself to more than 1500 patients. ple have higher treshold of pain
and agreeing easier to what their
Have you ever tried it to yourself? doctors suggesting. In Europe,
Yes. Because I hate to take pills, patients ask many questions.
I hate drugs.
In your very often trip around the So what do you think about the
world, what make you keep going? future of beauty?
The market ? It’s increasing. For example, there are more than
100 companies in the world producing filler. It’s incredible. So This is your first trip to Indonesia?
the market is very very increasing. Five years ago there are only Yes, and what amazed me is the doctors here are very enthusi-
a few companies producing filler, only one. astic and eager to learn, it’s different from in Europe. Indonesia
is very interesting. I can feel the hospitality. It’s the same across
Including your company? Asia but it’s different here. Of course it’s different than in Santo
No. No more company because now it’s too late for me. I prefer Domingo, where everybody is singing.
to act and work as a consultant which is better.
My last question is personal question. It’s an usual question in
First, you started as a nutritionist, why switch to mesothera- Indonesia, can you..?
py? You mean my status? (Laughing) I’m married and have a 22-
Because in my first practice, I have found that nutrition alone year-old son studying in Westminter and he wants to be a spe-
is not sufficient. One of my teacher in Necker-Enfants Malades cialist in data system. I have two cats. I love martial arts, karate.
taught me about mesotherapy, the classical one. And after this I swim, competition swimming. I did a lot of sports, horse riding
lecture I though it’s not possible to practice without mesothera- and everything. What more do you want to know ? Give me a
py. The beginning was 5 years after I started my practice I knew million dollar.. just kidding.
about mesotherapy then I took lessons, I tried and (the result
was) succesfull. Twenty seven years ago mesotherapy was not
only for beauty but of course for pain. At that time, mesolift
wasn’t even exist and wasn’t thinkable. I also learn about the
work (of mesotherapy), magnetic field of the body, which later
brought me to pollution, chemical pollution. It’s all the same,
free radicals. In lessons, in France, we have to talk not only 1950 Birth in Paris
about meso, but also about nutrition, pollution, macronutrition 1975 Graduated as a medical doctor (MD) in Necker-Enfants Malades
and many things that can help patients. But the food in Europe Paris, France
is different with the food you have in Asia. 1981 Graduated in Mesotherapy from Necker Hospital in Paris, France
1981 Member of the French Society of Mesotherapy
1986 Graduated in Nutritional Medicine from Saint Michel Hospital in
So you combine mesotherapy with nutrition?
Sometimes I use it alone sometimes I combine with nutrition 1986 Founder of Bionuclea (cosmetic company), inventor of Mesogel
and antioxydants. 2002 Registered in London, UK (private practice in Mesotherapy and
Do you have any message for practitioners and patients in In- 2003 Cofounder of Antioxydative Meso Therapy concept with Dr André
2004 Antioxydative Mesotherapy trainings in France
I think the patients in town will be suffering very shortly to pol- 2005 Speaker on Mesoplus Therapy at the World International Congress
lutants and there’re going to be more cancer, more stress. The on Antiaging in Monte Carlo, Monaco
traffic is incredible, lot of big cars. It’s the mentality. If you have 2005 Speaker at the 6th ICOS in Istambul
big cars the mentality is different. I don’t know about the village 2005 Trainings in Luxor centre in Almaaty, Kazakhstan
2005 2-day training in London, UK
but I think we have the same problem in the city. They eat Ameri-
2005 Speaker in Congrès International de Médecine Esthétique, Paris
can food so we will have obesity, we will have cancer.
2005 Workshop and speaker on Antioxidative Mesolift, Dermoesthetic
Congress in Bratislava, Slovakia
Where can I read about the antioxidative mesotherapy? 2006 Workshop Antioxidative Mesolift in Dermaparty congress (Smok-
It will be published in a shortwhile, I hope. The book will be ovec Slovakia)
about the foundation of mesotherapy that many doctors don’t 2007 Trainings of Antioxidative Mesolift for doctors during Antiaging
congress in Monaco (March)
know. And not only for beauty because pain therapy is (also)
2007 Trainings for Middle East doctors in Cairo
very important. 2007 Course in Hopital Tarnier (Diploma for injections technics) in Paris
2007 Speaker on Mesolift to RIDES assiociation in Bendor (France)
Will this information will be available in the internet ? Because 2007 Speaker at the 7th ICOS in Istambul (workshop)
if you want many people to know about this knowledge you’ve 2007 Paris Communication and workshop at the 9th ESCAD congress
(The Mitochondrion: the real aim of the Mesotherapy ?)
got to make it available in the internet?
Of course. But after the course.
Case Report of Mesoalopecia
Dr. Regine Rina & Dr. Reza Y. Purwoko, Sp.KK
A 24 years old female consulted a physician for suddenly
having a localized hair loss one week before. She told the
doctor that she has always used good quality products for her
hair. Her history told no similar symptoms in family, no autoim-
mune diseases, and no atopy.
Physical findings are patchy hair loss with follicular opening,
normal skin of the scalp, smooth, slightly erythematous. There
is no visible signs of inflammation, no scarring and no atrophy.
The hair pull test was positive at the peripheral of the patch. The
exclamation point hairs and nails abnormalities were not found.
She was diagnosed as alopecia areata.
The psysician treated her with intradermal injection of Triam-
cinolone acetonide 10 mg/mL 0,1mL (using 1mL syringe and self and weaken confidence. These implications have helped to
Mesalyse 32-gauge), followed by point per point superficial build a multibillion dollars business around the globe. In Amer-
intradermal and nappage intraepidermal injection of mesoalo- ica alone, 25 billion dollars were spent in this industry every
pecia therapies. A combination of intralesional corticosteroid year. It’s no wonder then if many claims have arisen to state that
with mesoalopesia were given every 2 weeks for five times. The various products can be used to treat alopecia or baldness. Food
cocktail of mesoalopecia consists of Minoxidil, Biotin,and Dex- and Drug Administration can’t ban these false products because
panthenol. yet no harm were done. So it lies to true scientists and genuine
practitioners the responsibility to give proper explanation and
For home treatment the psysician gave her topical Minoxidil care to patients. From treatments available, mesoalopecia has
2%, to be applied twice daily just on the affected area. And oral shown as one new hope in giving better nonsurgical therapy for
supplements for nutrifying the growth of hair, once a day. alopecia, in this case report, alopecia areata (AA).
The initial regrowth was seen in 4 weeks. There were several Definiton
hair shafts approximately 5 mm of length and several vellus AA is a nonscarring type of alopecia that presents as a localized
hair of the patch. At further treatments, the hair regrowth was loss of hair, round or oval shaped (patchy hair loss). AA can af-
significantly increased, either normal hair shafts or vellus hair. fect any hair-bearing areas. The most common presenting site is
Afterwards we treated her only with mesoalopecia. At her last the scalp, but other areas such as the eyebrows and the beard
treatment, the hair regrowth was seen in almost all of the af- areas may demonstrate hair loss with or without scalp involve-
fected areas (more than half of the area) with a predominantly ment. There are several other patterns of hair loss that may be
appearance of normal hair shafts. The mesotherapy was contin- seen in AA. Alopecia totalis (AT) refers to the total absence of
ued once a month and daily home treatment was continued too, scalp hair and alopecia universalis (AU) is complete loss of all
as a maintenance therapy. body hair.
Studies have shown that people underwent hair loss can ex- Prevalence of AA in the US general population is 0,1-0,2% and
perience psychological stress and disturb their perception as worldwide prevalence of AA is similar as in the US. All races and
s tudies have shown that people underwent hair loss can expe
psychological stress and disturb their perception as self an
both sex are affected equally by AA. AA can occur at any age
from birth to the late decades of life. Peak incidence appears to
of patients and most commonly seen in patients with severe
forms of AA.5
occur at age 15-29 years. As many as 44% of patients with AA
have onset at younger than 20 years, and onset in patients older Precipitating factors can be found in 15,1% of patients with AA.
than 40 years is seen in fewer than 30%.5 Major life events, febrile illnesses, drugs, pregnancy, trauma,
and other events had been reported, but no clear conclusions
Pathophysiology can be drawn. Despite these findings, most patients with AA fail
The pathophysiology of alopecia areata remains unknown. to report a triggering factor preceding episodes of hair loss.5
Many evidences support the hypothesis that AA is an autoim-
mune condition. The process appears to be a T-cell mediated, Diagnosis
but antibodies directed to hair follicle structures have also been Diagnosis usually can be made on clinical grounds; a scalp
found in AA patients. Antibodies to anagen phase hair follicles biopsy was seldomly needed, but can be helpful when clini-
were found in as many as 90% of AA patients compared to fewer cal diagnosis less certain. The most characteristic feature is a
than 37% of control subjects.1,5 The outer root sheath is the peribulbar infiltration, which was described as appearing similar
structure targeted most frequently, followed by the inner root to a swarm of bees. The infiltration was often spared and usually
sheath, the matrix, and the hair shaft.5 As a results, the growth involves only few affected hairs in biopsy specimen.
of the hair is impaired and the shaft is subsequently narrowed
and tends to break off at the skin surface. The hair loss is poten- A significant decrease in terminal hairs is associated with an
tially reversible because the inflammatory process spares the increase in velllus hairs, with a ratio of 1, 1:1 (normal is 7:1).
stemcell rich bulge area.3 Other helpful findings include pigment incontinences in hair
bulbs and follicular stellae. A shift occurs in the anagen-telogen
Clinical Features ratio, which is not specific. The normal anagen-telogen ratio is
AA is often asymptomatic, but some patients (14%) experience approximately 90% to 10%; in AA 73% of hairs were found to be
burning sensations or pruritus in the affected area.5 Likely, it in the anagen and 27% in the telogen.5
was noticed by friends or hairdressers. The absence of clinical
signs of inflammation is remarkable because histopatologically Differential Diagnosis
there are always inflammatory infiltrations around hair follicles The other problems to be considered include trichotillomania
in active lesions. The scalp appears normal in AA, with follicular (unusual shapes and sizes), tinea capitis (erythema, scalling,
openings, no scarring and no atrophy. The presence of smooth and crusting locally on the scalp), scarring alopecia and post-
slightly erythematous (peach color) or normal-colored alopecic traumatic alopecia (the absence of follicular ostia or some de-
gree of atrophy) and telogen effluvium (mimicking diffuse pa-
tern of AA).
The presence of “exclamation point” hairs, particularly at the
periphery of affected areas, is pathognomonic but that is not Treatments
always found. These short broken hairs, whose distal ends are Treatments are used to be believed to stimulate hair growth,
broader than the proximal ends, illustrate their inherent sequent but no evidence exists that they influence the ultimate natural
of events: follicular damages in anagen and then a rapid trans- course of disease. The most common therapies include corti-
formation to telogen. A positive pull test at the margins of the costeroid injections, corticosteroid creams, minoxidil, anthralin,
patch usually indicates that the disease is active, and further topical immunotherapy, and phototherapy. The choice of agents
hair loss can be expected. depends on patient’s age (children do not always tolerate ad-
verse effects), extent of conditions, and the patient’s personal
Nail abnormalities can be seen in patients with AA. Pitting is the preferences.
most common finding. Nail involvement was found in 6,8-49,4%
For adults with less than 50% scalp in-
volvement, the first option usually is an
intralesional corticosteroid, followed
by corticosteroid cream, minoxidil, and
anthralin. For adults with more than
50% scalp involvement, topical immu-
notherapies and phototherapies are
additional options. First Condition After 10 Weeks of Treatment
Both systemic and topical psoralen plus UV-A (PUVA) thera-
Intralesional steroid (Triamcinolone 2,5-5 mg/mL) is the first line
pies have been used. The initial response rate varied from
treatment in localized patches. In a study including 84 patients, re-
20-73%. The relapse rate is high (50-88%). Most patient re-
growth on treated areas was present in 92% of patients with patchy
lapse within few months after treatment stopped. Adverse
AA and 61% of AT. Regrowth usually was seen within 4-6 weeks in
effects include burning and possibly an increased risk of skin
responsive patients.5 Less than 0,1 mL was injected intradermally
per site using 30-gauge needle, and injections were given to cover
the affected areas (approximately 1 cm between injection sites) for
Topical immunotherapy is defined as the induction and peri-
maximum volume of 2-3 mL. Injections are administered every 4-6
odic elicitation of an allergic contact dermatitis by topical ap-
weeks3,4,5 Adverse effects mostly include pain during injection
plication of potent contact allergens. Commonly used agents
and minimal transient atrophy (10%). The atrophy rarely can be se-
are diphencyprone (DPCP) and squaric acid dibuthylester
vere and permanent.5
(SADBE). Treatments are provided weekly. The patient is first
sensitized directly on the scalp with 2% concentration on a
Few studies have been performed regarding the efficacy of topical
small area (2x2 cm2), the following week a low concentration
steroids, and their usefulness remains under debate. Fluomcino-
(0,0001%) is applied. Then, the concentration is increased
lone acetonide cream 0,2% or Betamethasone dipropionate cream
slowly every week as needed until a mild, tolerable allergic
0.05% twice daily induced a satisfactory response in 61% patients;
contact dermatitis is elicited. The median time to achieve sig-
children younger than 10 years responded better.3,5 Rates of re-
nificant regrowth was 12,2 months. Some patients showed
growth vary greatly (27-89%).5
regrowth after 18 months. The relapse rate after reaching sig-
nificant regrowth was 62,6%. Most studies have a success
Minoxidil appears to be an effective treatment of AA in patients
rate of 30-50%.3,5 Adverse effects include cervical lymph-
with extensive disease (50-99% hair loss). Response rates in that
adenopathy and pigment changes. The mechanism of action
group vary from 8-45%. The 5% solution appears to be more effec-
is unknown; may be antigenic competition. q
tive. No more than 25 drops are applied twice daily regardless of
the extent of the affected area. Initial regrowth can be seen within References
12 weeks, but continued application is needed to achieve cos- ,
1. Allan BF Jr, Steven RF Aaron SK, Beth DC. 20 Common
metically acceptable regrowth. Minoxidil is usually well tolerated. problems in dermatology 2000;18: 256-61
2. Thomas BF Richard AJ, Klaus W, Dick S. Color atlas & synopsis
Adverse effects include local dryness or irritation (7%) and facial of clinical dermatology, common and serious diseases, fourth
hypertrichosis (5%). The exact mechanism of actions remains un- edition 2001; 27: 928-31
clear. It most likely has a direct mitogenic effect on epidermal cells, 3. Francisco AK, Francisco JA. Dermatology just the facts 2003;
both in vitro and in vivo.5 ,
4. Irwin MF Arthur ZE, Klaus W, K Frank A, Lowell AG, Stephen IK.
Volume I Fitzpatrick’s dermatology in general medicine, sixth
The efficacy studies of anthralin unfortunately were uncontrolled. edition 2003; 10: 641-3
5. Chantal B, Harvey L, Jerry S. Alopecia areata 2006.
A 2004 study showed no benefit. Other studies showed a response
6. The National Institute of Arthritis and Musculoskeletal and Skin
rate of 20-75% for patchy AA and 25% for AT.5 Diseases. Questions and answer about alopecia areata.
Sebelum Perawatan Masa Perawatan Setelah Perawatan
For training purposes we have worked out a model of an aging face made of special
material and resembling a human face - with pronounced "wrinkles" and "folds", "soft
tissue ptosis". This model will help a doctor to practice various manipulations and
From the beginning of the 1998, operations and to acquire experience.
the scientists, inventors and plas-
tic surgeons from Moscow, father The APTOS Model will help our colleagues to master not only our new techniques but
and son, Marlen and George Sula- also other operations and manipulations (correct injection of various gels, medicines,
manidze, having large experience
of rejuvenation operations, such is
face lifting, and wishing to make
For long-lasting, yet minimally invasive lifting of the skin and subcutaneous tissue of
the operations as easy for the pa- the face, neck, breasts, brachial inner surface and buttocks with small (up to 1 cm) inci-
tients as possible, without post- sions.
operative hems, pains, different
complications and nonsuccessful Such lifting is performed with the help of the APTOS Needle, a unique device which
makes it possible to suture soft tissue with small stitches just subcutaneously without
results, invented new technologies
the suture thread emerging on the skin surface.
and methods for such operations
and manipulations. These methods As though an invisible surgeon under the skin is suturing the flabby tissues grouping
have developed the possibilities of them in the required places in order to impart them elasticity and create new contours
the aesthetic and plastic surgery. of the skin with no scars left.
Soft Tissue Augmentation :
Use of Hyaluronic Acid
as Dermal Filler
THE HISTORY OF HYALURONIC ACID correction of wrinkles. If anesthesia was required a topical anes-
Karl Meyer and his John Palmer isolated a chemical substance thetic cream is applied to the area under occlusion at least one
from the vitreous jelly of cow's eyes in 1934. The name hy- hour prior to the treatment.
aluronic acid was derived from hyaloid (vitreous) and uronic
acid. The identical structure of hyaluronic acid in all species and Techniques of injection
tissues makes it to use as a biomaterial in health and medicine. 1. Linear threading technique: the full length of the needle is
Hyaluronic acid is present in many places in the human body. inserted in the middle of the wrinkle and the substance is
It gives volume to the skin, shape to the eyes and elasticity to injected while pulling the needle slowly backwards so that
the joints. the threads of the gel are placed lengthwise in the wrinkle.
2. Serial puncture technique: multiple injections are placed se-
PRODUCTS OF HYALURONIC ACID rially along the length of the treated wrinkle/fold. It is made
The older products of hyaluronic acid are ranging from animal closely together so that it merges into a smooth continuous
to nonanimal source and allergic prone to hypoallergenic prod- line which lifts the wrinkle.
ucts. The major disadvantage of the common hyaluronic prod- 3. Fan technique: the needle is inserted at the periphery of the
ucts was the need to be mixed with a chemical thinner before area to be treated as when using the linear threading tech-
usage due to the increment of free radicals. Some products nique. After injecting one line the direction of the needle is
now available in the market are free of this need, for example changed and injected as before along a new line.
Visagel. 4. Cross hatching technique: the needle is inserted at the pe-
riphery of the area intended to be augmented and injected
INDICATIONS AND CONTRAINDICATIONS OF as when using the linear threading technique. The needle
DERMAL FILLERS is withdrawn from the skin and inserted 5-10 nm adjacent
Indications: depressed scars: postsurgical, traumatic, postacne to the first puncture site and injected in the same way. This
or other diseases, wrinkles and folds, lip sculpting, enhance- procedure can then be repeated at right angles to the origi-
ment of facial contour, periocular melanoses and sunken eyes. nal lines.
Contraindications: keloidal tendency, hypersensitivity to prod-
ucts as demonstrated by positive skin testing, unrealistic expec- Successful treatment
tations. Where to inject is the key to successful treatment. For best re-
sults the products should be injected within the product recom-
PROCEDURE mended tissue depth.
A detailed clinical examination and history taking and counsel-
ing of expectations and limitations of the product are essential. Posttreatment care
A preoperative photograph and written informed consent are The area should not be touched for 6 hours after the injection,
recommended. No anesthesia is necessary when injecting for and should not be exposed to extreme heat or cold. Touch up
F iller is a practical and instant solution relatively free of
side effects for patients who wish to look young without
undergoing major surgical procedures.
treatment can be given after 2-4 weeks if necessary.
Erythema, swelling, pain, itching, discoloration and tenderness
at the implant site. Resolution is spontaneous within one or
two days. Substance related adverse effects such as swelling
and induration are rare (less than 1 in 2000 treatments). A short
course of oral steroids or intralesional hyaluronidase may be
Filler is a practical and instant solution relatively free of side
effects for patients who wish to look young without undergo- and augmenting lips and lip contours. It is injected into the mid
ing major surgical procedures. However the effects of fillers or deep dermis by linear withdrawal technique (tunnel or criss-
like hyaluronic acid are temporary and injections need to be cross-technique), by serial puncture technique or by a combina-
repeated once in 6-10 months. tion of these techniques.
REFERENCES Visagel contains less then 0,15 µg/ml protein which came from
Vedamurthy M. Soft tissue augmentation - Use of hyaluron- the hyaluronic acid as raw material. The endotoxin level of it is
ic acid as dermal filler. Indian J Dermatol Venereol Leprol less then 20 EU/ml product and the divinylsulfon level of Visagel
2004;70:383-7. is 0,0004 mg/ml product. The results of the biocompatibility tests
show clearly, that there is no adverse effect. For product release
A NEW HYALURONAN: VISAGEL a cytotoxicity test was done for each lot in order to verify the
Visagel is a new hyaluronan product made with help of Visalink biological effect of the cross linking reagent.
technology. The technology is the only one in the world that Visagel guarantees a sterility assurance level of ≤ 10-6 and a bio-
ensures complete crosslink of hyaluronan. Thus make Visagel compatibility that meets the requirements of international stan-
able to be an outstanding elastic material and the only hyaluro- dard ISO 10993-1.
nan product that doesn’t need thinning agent when used. It is
made from the purest and highest quality hyaluronan material A word about Visagel from doctor Alain Gondinet after giving
and therefore requires no allergy test before administration. a course of Visagel filler, “Visagel is pure, 100% pure. This is a
The end result is natural and lasts longer than another product. natural product. It is soft, elastic, and easy to use and of course
In comparison with another hyaluronan, the use of Visagel is it is cheaper than the other. It can be used for deep wrinkle, shap-
cheaper because it has higher performance and longer lasting ing the nose, glabella, no superficial wrinkle. It is invented by a
result. German company and they have studied it for three years. The
study is very interesting because it has no reaction, no side ef-
Visagel is indicated for treating medium and deep cutaneous fect because it is very pure and contains no other chemical agent
depressions such as wrinkles, folds and other defects, restor- in it. So it is easy and safe to use by doctors. So it is soft, easy,
ing or creating volume in facial contours (cheekbones, chin) .
and safe” q
Stem cell therapy will keep progressing and the world is waiting for
animal stem cells that can be used in human.
S everal years ago, stem cell therapy seems so far away and won’t be denaturated even in room temperature.
unreachable. But recently, stem cell is becoming the latest • Stem cell therapy awaited revolution is how to increase the
trend in aesthetic and blood related diseases. And the therapy is productivity of stem cell. The ways that have been tried in-
real and already available in the market. Knowing the latest in- clude growth factor and platinum wire. Platinum wire can
vention is crucial if we want to know what’s right and what’s just produce infrared that can penetrate body up to 15 cm.
bogus. Here are several facts that we’ve compiled from around • This therapy is still expensive, ranging from USD 7,000 for
the world. animal stem cell to USD 20,000 for human stem cell cancer
• Nowadays, single layer stem cell is more popular than mul- therapy.
tiple one. Single layer stem cell can be found in thymus,
embryo, placenta and serum. The famous serum type is the Stem cell therapy will keep progressing and the world is waiting
popular cord blood or umbilical cell that are being kept in for animal stem cells that can be used in human. q
cord banks (Kalbe Farme in Indonesia)
• Recent foundings in stem cell therapy:
1. When an old rat was transplanted with a young thymus
rat, everything in the old rat become younger. Thymus is Excerps from Lecture of Prof. Dr. Leow Chong Ngan:
found to have a good antiaging effect, though actually
thymus is an immune organ. THE AGEING PROCESS CANNOT BE PREVENTED
2. Embryo is said to be able to protect DNAs, for example BUT YOUTHFULLNESS CAN BE REGAINED
to protect people from mutation and injury in nuclear
facilities. Embryo is also said to be a new anticancer Stem cell products are available from Switzerland’s
hope. company EroCell. The stem cells are extracted from
3. Placenta is said to have excellent aesthetic purposes, for bovine thymus, placenta, embryo and serum. EroCell
example in hormonal treatment. And serum (cord cell) placenta are indicated for promoting blood circulation in
is proven to cure almost anything related to blood, for wound healing, climacteric disturbances, early ageing,
example curing anemia aplastic, leukemia and diseases while EroCell serum for ulcer, myocardial infarction and
of vessels and hearts. cerebral circulatory disorders. EroCell embryonal can be
given for aging related diseases such as chronic urethri-
4. Fetal preputium stem cells can produced sizable epider-
tis and prostatitis, regeneration of connective tissue and
psycho-physiological weaknesses such as insomnia, lack
5. In patient with parkinson, with the right stem cell thera-
of concentration and other mental performances.
py, tremor can subside in three days. Stem cell can also
be used for spinal cord injury.
These products can be given directly to the skin or
• Stem cell use depends on patient’s need. For aesthetic prob- orally, intravenous, intramuscular, intracutaneous or
lem, placenta was used as a main therapy and if patients are subcutaneous, depend on consultation. EroCell is given
healthy, all kinds of stem cells can be used in combination. two to three times weekly with a total of 24-36 doses for
• A method known as “completeness” is when hundreds of a cycle of treatment.
each type of stem cell is used to get the best result. This
method is popular because being so small in peptide size, it
Administered using microinjections (0.2-0.3 mL) into the affected area and,
possibly, via some simple acupuncture points, such as stomach 37, stomach
40, stomach 44, large-intestine 11, spleen-pancreas 6, and gall-bladder 23.
Tissue tone treatment
• Skin slackening and tissue revitalisation
• Bio lifting of large areas of the body
• Firming of the gluteus muscles.
• Administered using collagen needle (13 mm 30 G) and mesotherapy
needle (4 mm 27 G).
• For firming gluteus muscle, infiltrate to the following areas:
1. From the centre of the gluteus muscle proceed with 4 injection lines,
in a sunburst shape (superiorly, inferiorly, towards the medial side,
towards the lateral side).
2. Along the subgluteal furrow.
• Used in oedematous-fibrosclerotic lipodistropy or cellulite. It can be
used saddlebags, root of the thigh, knees, and arms.
• Administered using microinjections (0.2-0.3 mL) via some acupuncture
points such as spleen-pancreas 6, spleen-pancreas 9, spleen-pancreas
10, and liver 11.
• Administered using small inoculation wheals (0.2-0.3 mL).
• Infiltrate the following areas:
1. From the clavicle down along the breast muscle with 3 parallel
2. From the areola go on with 4 injection lines radially (in the upper
part, in the lower part, towards the medial side, towards the lateral
3. In the area below the breast, along its insertion on the thorax.
Mesotherapy as a Part of
Obesity Nutrition T
to have high threshold of hypnosis (hard to fall under influ-
ence). Sometimes, hypnotherapy should be administer re-
O besity is one of new arising degenerative disorders in
urban areas. The treatment remains as one of the great-
est obstacles in the world of therapeutic medicine due to
peatedly to achieve an optimal result.
Several nutritionists are developing “nutritional hypnother-
the many factors comprising the disease. Nutrition is one of
apy” science that dealt with the unconcious mind of patients
important factors in preventing and curing obesity. The way
in order to make them want to eat the healthy food uncon-
people eat describe who they are and changing it can be a
gigantic hindrance. Because of bad nutrition, obesity treat-
ment seems to face failure, often more than less.
Other advantage with hypnotherapy is patient can be made
in relaxed condition, ‘fearless’ and feel no pain when he/she
THE DIFFICULTY TO RESIST FOOD TEMPTATION
is injected without prior anasthetic.
The city life brings a whole new way of life, one of it is a cus-
tom to eat for living and no the other way around. The food
MESOTHERAPY AND NUTRITION THERAPY
this new life brings is high in simple carbohydrates, sugar,
Obesity should be treated to prevent further complications
dan fat. Uncontrollable eating behaviour will make people
such as diabetes, cardiovascular diseases, early aging, can-
gain excessive weight, obesity, and all degenerative compli-
cer etc. It is also being treated for aesthetic factor. Meso-
cations cause by it.
therapy can be very useful to delay tissue early ageing and
improve patients appeareance with its mesolipo.2
Studies have shown that people find it hard to stop eating
good food no matter how bad. What is needed is a high self
Below are case reports of obesity that were treated by nutri-
control while obese people usually show low discipline when
tion alone or combined with mesolipo.
facing food temptation. Diet consultation which is made to
give examples of healthy food to reduce weight often failed.
Male, 30 year old, single, height 175.0 cm, weight 131.5 kg,
The main reason of this failure is the assumption that when
BMI 42.9 kg/m2, total body fat 61.9 kg (Imron, Bioelectric Im-
people know how to eat right they’ll do it right away. Actu-
pendance), belly diameter 128.0 cm (Figure 1A, 1B).
ally, those two things are very different. Although patients
have known what healthy foods are their heads keep craving
The treatment started with a conventional diet consultation
for unhealthy foods.
which taught how to choose low caloric food. When the re-
sult seemed unsatisfactory, the therapy was changed to hyp-
The most important thing to remember in therapy is to
notherapy and patient was given suggestion to resist high
change people mind set that if they eat right they can and
will lose weight. Hypnotherapy is one of effective methods
to change this mind set with only 5% of patients showing
Other therapies that were given included individual low
Therapy Prof. DR. Dr. Walujo Soerjodibroto, SpGK
Department of Clinical Nutrition
Faculty of Medicine
University of Indonesia
dose sibutramin once daily, aquapuncture to abdominal wall
to fasten the feel of fullness, and exercise in the form of walk-
ing 1 hour a day. Patient didn’t do the work ups.
After diet consultation was changed to once a week hypno-
therapy, patient gradually started working ups, from walk-
ing to running. In latter days patient was given mesolipo in
stomach, upper limb and wing areas. (cocktail combinations
of : Phosphatidylcholine, Organic Silicium, Centellasial, L-
Carnitine, Dermaproc). Oral medication was tappered off
when hypnotherapy had shown to be a promising result.
Therapy was conducted in 3 years period and at the end of
program the weight had reduced to 83.2 kg, BMI 27,2 kg/m2,
total body fat 27,3 kg (Imron, Bioelectric Impendance), belly after 3.5 months
diameter 86.2 cm (Figure 2). There were no complains from
patient and significant complications. Patient has married,
work, and live in other province. after 5 months
Male, 21 year old, single, height 171.0 cm, weight 87.6 kg, BMI
30.0 kg/m2, total body fat 25.6 kg (Imron, Bioelectric Impen- after 3.5 months
dance), belly diameter 93.8 cm. Patient was used to consume
slimming medication that made him urinate more often and
diarrhea and when we first met him, he was still obese with after 5 months
a very flabby abdominal wall (Figure 3). before
This patient was given once a week hypnotherapy to make
him eat low caloric and enough protein food. Patient under-
went mesolipo once a week in abdominal stomach and was
after 3.5 months
recommended to exercise, at least one hour walking a day. At
first, patient was given low dose sibutramin every morning
and was tappered off when hypnotherapy kicked off. Meso- after 5 months
therapy treatment is administered twice a week at abdominal
area (Dermaheal-LL, with Dermaproc or Xylocain).
O besity should be treated to prevent further complications such
as diabetes, cardiovascular diseases, early aging, cancer etc. It
is also being treated for aesthetic factor. Mesotherapy can be very
useful to delay tissue early ageing and improve patients appeareance
with its mesolipo.
The treatment lasted for 5 months and at the end of it his Bioelectric Impendance), waist diameter 70.8 cm, and bel-
weight was 82.0 kg, BMI 28.1 kg/m2, total body fat 22.3 kg ly diameter 74.2 cm (Figure 6). No complains were made
(Imron, Bioelectric Impendance), belly diameter 81.2 cm (Fig- during teatment.
ure 4B). The other interesting part was the improvement of
renal function, from CCT 65,2 cc/min to 82,2 cc/min. CONCLUSION
The target of obesity treatment is to change the way patients
This patient was given once a week hypnotherapy to eat. This change needs to be permanent because when pa-
make him eat low caloric and enough protein food. Pa- tients only depend on medication, weight will return or even
tient underwent mesolipo once a week in abdominal increase (yoyo effect).
stomach and was recommended to exercise, at least one
hour walking a day. At first, patient was given low dose There are many ways to change eating behaviour. Writer’s
sibutramin every morning and was tappered off when experience showed at first safe oral medication can be used
hypnotherapy kicked off. (nonlaxatives and nondiuresis) concordantly with hypno-
therapy and exercise. Medication therapy was tappered off
The treatment lasted for 5 months and at the end of it his when hypnotherapy has shown result. Acupuncture or aqua-
weight was 82.0 kg, BMI 28.1 kg/m2, total body fat 22.3 kg puncture also helped and mesotherapy (mesolipo) can be
(Imron, Bioelectric Impendance), belly diameter 81.2 cm done as latter treatment. Mesotherapy can be used from the
(Figure 4B). The other interesting part was the improve- beginning if the problem was only overweight and not obe-
ment of renal function, from CCT 65,2 cc/min to 82,2 cc/ sity. The main problem of mesotherapy is the price that is
min. relatively expensive.
Female, 27 year old, single, height 160.0 cm, weight 70.1
kg, BMI 27.3 kg/m2, total body fat 18.6 kg (Imron, Bio- Reference
electric Impendance), waist diameter 79.1 cm, and belly 1. Stradling J, Roberts D, Wilson A & Lovelock F (1998).
diameter 80.8 cm. Patient received hypnotherapy and Controlled trial of hypnotherapy for weight loss in pa-
aquapuncture once a week. At the latter time, aquapunc- tients, Int J Obesity, Vol 22, No 3, Page 278-281.
ture was changed to mesotherapy once every two weeks.
2. Wikipedia (2007). Mesotherapy.
(Phosphatidylcholine, Organic Silicium, L-Carnitine, Der-
maproc) Patient was asked to walk one hour every day
This program lasted for 4 months and the final weight
was 57.2 kg, BMI 22.3 kg/m2, total body fat 15.0 kg (Imron,
A Multi-tallented Cosmetologist
E xperience is not only the best
teacher for Rubin C. Jusuf S.Pd,
but also a key for a better success
Rubin Cosmeceutical provide the most complete products rang-
ing from skin & body therapeutic care (day/night cream, sun
block cream/gel, bleaching cream, AHA cream, toners, facial
in designing and formulating high- wash/cleanser, botu-like products, L-Ascorbic Acid serum, anti
ly qualified cosmeceutical –a blend irritant cream, anti aging cream, acne lotion/cream/gel, founda-
of cosmetics and pharmaceutical- tion, two way cake, loose powder, massage cream, face mask,
products named Rubin Cosme- etc), lip care and hair care (shampoo, conditioner, cream bath,
ceuticals, a patented brand image hair tonic, hair growth serum, etc).
trusted by beauty medicine exper-
tise and practitioners in Indonesia. ”Various test are done prior to marketing, such as Safety Test to
prove products’ safety and adverse effect, Efficacy Test to know
Having acne problems on his face for more than 10 years dur- its’ effectiveness and Clinical Test to test the product under der-
ing his adolescence, young Rubin tried many ways to solve his ”
matologists’ supervision, said Rubin.
problems and promised to help other people who have the same
problems if he succeeded. He finally succeeded in controlling Rubin has already known for his credible innovation and quali-
his problems and became more driven in studying cosmetics fied products which often become a standard and gain compli-
and formulation technique supported by research and develop- ments. ”I combine science, art, and technology to produce the
ment team composed of pharmacists, chemists and dermatolo- best and competitive product” said Rubin who also manage PT
gists, by combining medical, cosmetics, and aesthetic medicine. Sarana Estetika Industri.
”This is my biggest satisfaction” said Rubin who is also a source
person for applicative cosmetology and formulation for profes- ”I put my trust on Rubin for his special and different work. Rubin
sionals. He is chosen and trusted by more than 300 aesthetic ”
is a reflection of success, said Harijani, MSc, one of his steady
medical practitioners from Indonesia and all over the world such customer.
as Singapore, Malaysia and Brunei Darussalam. They come to
Indonesia for learning with Rubin directly and intensively.
PT. Sarana Estetika Industri
Phone. (021) 581 6455, 581 9233
Fax. (021) 581 9233
New Generation Retinoid:
New Treatment of Acne Vulgaris
Tretinoin was the first retinoid used in the treat-
ment acne. It is generally effective and widely
used but when used, dryness of the affected
skin may occur. More sensitive patients may
also experience redness, scaling, itching, and
burning. Now there is a new generation retin-
oid with minimal irritation : ADAPALENE.
Adapalene is a retinoid agent indicated for the
topical treatment of acne vulgaris. In clinical
trial, 0.1% adapalene gel has proved to be ef-
fective in this indication and was as effective
as 0.025% tretinoin gel, 0.1% tretinoin micro-
sphere gel, 0.05% tertinoin cream and 0.1%
tazarotene gel once every two days. It can be
used alone in mild acne or in combination with
antimicrobials in inflammatory acne and has
proved efficacious as maintenance treatment.
A cne is a chronic inflammatory disorder of the pilosebaceous
unit that affects almost everyone at some stage between
the ages 12 and 24 years. It is related to neither hygiene nor diet,
Adapalene has rapid onset of action and particularly favourable
tolerability profile compared with other retinoids, It has a unique
chemical structure 3 aromatic rings that make it more stable to
though there appears to be a genetic predisposition in severe light and adamanthyl structure that has less irritation effect.
cases. It is a multifactorial disease, the main pathophysiologi- These attributes can potentially promote patient compliance, an
cal factors that influence the development of acne are excessive important factor in treatment success. Adapalene is therefore
sebum secretion, abnormal keratinisation and desquamation of assured of a role in the first-line treatment of acne vulgaris.
sebaceous follicle epithellium ( comedogenesis ), proliferation
of propioninacterium acnes in the pilosebaseceous duct and
Waugh J, Noble S and J.Scott : Adapalene : A Review of its use in
Treatment of acne address the various factor responsible for it . the treatment of acbe vulgaris, Drugs 2004,64(13):(1465-1478)
They include estrogens and antiandrogen to reduce the impact
of androgen, antibacterial agent to reduce P acnes colonization
of the pilosebaceous unit, and retinoids to reduce hyperprolifer-
ation and keratosis of ductal corneocytes. Choice of treatment is
dependent on the type and severity of the disorder. If the acne
is mainly comedonal, retinoid are the first line treatmen. In the
case of inflammatory acne, topical and / or systemic antimicro-
bial agents may be used in addition to retinoid. In cases that fail
to respond to such treatment, oral isotretinoin may be used.
Look Charming with Acanthe
W omen and beauty are inseparable. Physical appearance is one of the most im-
portant things for women. Various cosmetics are therefore being produced to
satisfy women’s need. One of it is ACANTHE-Naturally Effective, a product made from
natural compositions proven effective to treat skin naturally. ACANTHE was brought
from Spain and distributed to Indonesia by PT FERRON PHARMACEUTICALS. Today,
ACANTHE has 8 products:
Acanthe Anti Wrinkle Flash Acanthe Caviar Eye Gel
ACANTHE ANTI WRINKLE FLASH is a formula made especially This formula is designed especially for sensitive areas around the
for wrinkles around the eyes. It is made from the mixture of mel- eyes. ACANTHE CAVIAR EYE GEL is caviar extracts proven effec-
hydran, laricryl, vitacell, and terminalia herbs. Melhydran acts by tive in dealing stress and tired skin and kantung mata. The active
moisten soft skin around the eyes, larycril acts not only moisten ingredients work properly and effectively on that areas so the skin
the skin but also help to reduce pores, refresh and tighten skin. Vi- is prevented from aging, and become soft, tight, and moist. Use
tacell acts by stimulating skin cells metabolism and regeneration. this eye gel during the night, when the regeneration is more in-
Terminalia, in the other hand, is useful for its effect on improving tensive.
Acanthe Sebum Regulating
Acanthe Anti-Wrinkle Treatment To overcome oily skin problems ACANTHE SEBUM REGULATING
ACANTHE ANTI-WRINKLETREATMENT is made from several com- came as a solution. This product is beneficial to tighten pores,
positions. One of it is Lactococcus Permet which moisturizes outer reduce sebum on skin, and refresh your skin. ACANTHE SEBUM
skin and sun blocks. Other component is hibiscus which acts in re- REGULATING composed of amino acid, peptides, and zinc com-
vitalizing skin cells, anti free radicals, gives nutrition to epidermal plexes, all of which act as a seboregulator, laricryl as a pore mini-
cells. Another one is Glicine Soja Protein known not only by it anti mizer and freshener, and vitacell as a skin revitalize and regenera-
wrinkle effect but also tightens, improves, and protects skin. The tor. Use it twice a day during morning and evening.
last composition is fomes officinalis which cleanses, tightens, and
moistens the skin. Apply ACANTHE ANTI-WRINKLE TREATMENT
on the face which has wrinkle and aging signs. Regular use im- Acanthe Lightening Cream
prove wrinkle, prevent and delay new wrinkle formation. The best
result will be seen after three weeks application. The same as ACANTHE LIGHTENING GEL, ACANTHE LIGHTEN-
ING CREAM makes skin looks lighter and treats hyperpigmented
areas. Its active ingredients are Ferulic acid, Waltheria Indica,
Citric Acid, and Gluconic Acid which give melanin control effect,
Acanthe BTX-like Cream while the other ensure a fast absorption. Regular use will prevent
Wrinkle often formed from someone mimic habit such as vertical melanin synthesis. Apply lightening cream during morning and
line between, eyes, horizontal line on forehead or line on mouth evening. For single spot, apply directly onto the area. The best re-
side. To resolve it, ACANTHE launch BTX-LIKE CREAM. This is s sult will be seen after two months application.
new generation formula with active ingredients obtained from
hibiscus flower seeds extract called hydrolyzed hibiscus extract.
This formula works by preventing wrinkle, reduce musle contrac- Acanthe Lightening Gel
tion so that expression line formation reduced. Beside, ACANTHE
BTX-LIKE CREAM also composed of vitamin E which acts on nutri- Acanthe lightening gel is formulated to lighten the skin, especially
tioning your skin, fights against biological aging, and relaxes skin. for hyperpigmented area. Ferulic Acid and Waltheria Indica are the
Apply ACANTHE BTX-LIKE CREAM twice a day during morning active ingredients which have melanin control, depigmentation
and night into clean and dry skin with gentle massage on face and and tyrosinase inhibition effects. While Citric Acid induces epider-
neck where expression lines easily occur mal desquamation, and Gluconic Acid has Cu2+ chelating activity
in melanocytes. Regular use will reduce spot pigmented skin and
makes it lighter. Apply ACANTHE lightening gel during morning
and evening. For single spot, apply directly into exposed area.
Acanthe Anti-Irritation The best result will be gained after two months application. This
ACANTHE ANTI-IRRITATION is made from mixed purified Com- product is best recommended for oily skin.
frey, Licorice, Burdock, and Cassia Augustifolia roots. This combi-
nation formula designed to overcome irritation and stress on the ACANTHE-Naturally Effective is distributed by PT FERRON PAR
skin. ACANTHE ANTI-IRRITATION helps prevent skin damage and PHARMACEUTICALS in the end of 2006 and for further informa-
also improve and prevent irritation while soften and relax skin. tion please contact PT. Ferron 021-7884-3633 (Kustanto)
What's New In Light Therapy
Improved Precision Yields Results
The World's Most Sophisticated, Expandable Platform for Aes- act and calculated pre-sets, all the parameters are adjustable so
thetic Treatment Technologies it offers flexibility too. The operator can create a more selective
treatment for each
L umenis released its 4th Generation IPL technology two years
ago, called Lumenis One. This is the most advanced IPL re-
leased so far. The Optimal Pulse Technology (OPT) means that
Lumenis One tech-
nology has been
approved by FDA in
the machine delivers very precise energy. The OPT light delivery
the USA and listed
is more controlled and the energy level can be adjusted to suit
in TGA in Australia.
the individual skin type and condition. This makes it safer than
This proofs its high
earlier machines, and gives very predictable results. before and after IPL treatment for hair reduction using
level of safety. the Lumenis I in US clinical trials.
Lumenis One can be used to
treat a variety of skin condition, ‘The OPT light delivery
from reducing the appearance is more controlled and
4th generation of
of fine lines and wrinkles to the energy level can be
IPL, Lumenis One
the fading of pigmented birth- adjusted to suit the indi-
unites 4 gold stan-
marks, even port wine stains. vidual skin type’
While it is most usually used to before and after IPL treatment of age spots using the Lumenis I
on one platform :
in US clinical trials.
treat all forms of pigmentation, OPT also offers improvement in
The IPL for skin
rosacea, vascular lesion and capillaries. In regards to rosacea,
some patients experienced prolonged facial flushing and, this
and treating vascu-
is the only machine that has high rate of success in treating this
lar and pigmented
condition. The texture of the skin is also improved. It reduces
lesions, the Light-
the appearance of fine lines and wrinkles, reduces pore size and
sheer diode laser
evens out skin tone and colour.
hair reduction, the before and after IPL treatment of actinic keratosis and
The technology works by optimizing the wavelength so that the hyperpigmentation using the Lumenis I in US clinical trials.
energy is absorbed only by the unwanted melanin, raising the
for treating leg
temperature and causing the pigment to break up without dam-
veins and deeper vascular lesions, and the Aluma with FACES
age to the surrounding tissue.
(RF) technology for the treatment of wrinkles, fine lines and skin
Lumenis One system is faster than previous models. ‘With older
machines, the operator would take 30 to 40 minutes to treat the
The system’s key features is the OPT, integrated contact cooling
whole face. With OPT, it takes only 10 minutes. For photo
system, numerous presets, easy custom settings, and an intui-
rejuvenation, patients, used to need five or six treatments,
tive touchscreen software interface. These features enables phy-
with OPT the same results can be achieved in just two or three
sicians to provide increased patient comfort, faster treatments,
and easily tracked patient information. It also has an internal
database for maintaining patient records and adding treatment
The machine’s accuracy also gives improved results. There is
notes and clinical indicators. q
less scatter, even with large pigmentation spots, and the treat-
ment is therefore more effective. While the machine has very ex-
Ask The Reference
Dear Dr. Reza,
I have heard a lot about Acthyderm, but I am still not sure about
its usage. Do you use Acthyderm for your patients? Are they
satisfy with the result? Thank you.
Dr. Rita, Surabaya
The straight answer for your first question is YES. I use
Acthyderm to treat my patients. Acthyderm is a device to
utilize skin electroporation of for transdermal vehiculation of
pharmaceutical and cosmetic products. This device is used with
mesoporation, a noninvasive technique of transdermal drug
Acthyderm allows a simple, rapid, and effective transdermal
therapy, providing surprising results without surgery or very satisfied with the result. And I agree with her, my patients
injections. It is used for many dermatologic cases such as are also amazed with the effect. I hope this short information is
mesomelasma, mesoglow, mesolift, mesoacne, mesostretch quite helpful for you. For more information about Acthyderm,
mark, mesoalopecia, mesolipo, chubby cheek, double chin, you can contact us.
sagging arms, breast treatment, and many more. Besides
mesotherapy procedure, acthyderm is also used for local Warm regards,
anaesthesia for minor procedure using lidocain or emla. Dr. Reza
The effect is directly seen for most cases. For mesomelasma,
mesoacne, and mesolipo, it might need 2 or 3 times treatment
for the effect to be seen.
Acthyderm was launched at 2001 and since then it has been
used in over 20 countries, including Indonesia. Prof dr. Diana
Yusuf, Sp.KK in Medan also uses Acthyderm for her patients.
She said that so far, the effects are so amazing and patients are
etic Cream for MTS Dr. Reza Y. Purwoko, Sp.KK
Dear Dr. Reza,
I used MTS Roller 1 mm to treat acne scar on my patient's face
and she was satisfied. The problem is she felt pain when I rolled
her face. According to your experience, what is your sugges-
Since BLT cream creates a layer on skin, you need to wash pa-
tion to reduce the pain? What kind of medication do you use
tient’s face with normal saline after each use. Wash your hands
with MTS roller? Is it different with medication used with me-
Drugs used with MTS roller and mesotherapy are actually the
same. You can read the cocktail in Aesthedica magazine first edi-
Dr. Riswan, Papua
tion. In mesotherapy, we use needle and drugs will be inserted
with injection. With MTS roller, we apply the medication first
then we create microinjury for that medication. It is like we are
Answer pouring the medication to skin. It is better that we use creamy/
jelly-like medicines instead of a liquid mesomedication as it will
not evaporate easier than the liquid one. We get this thicker me-
Dear Dr. Riswan,
somedication by mixing the mesococktail with a nonreticulated
hyaluronic acid (Hyalift or Hyaluronic Acid Mesomedica) meso-
MTS roller indeed can cause pain. You can use anesthetic cream
product, Idabae, or other products.
such as lidocaine 1% cream or other cream. But in my experi-
ence, BLT cream gives better result. BLT cream contains 3 active
Sincerely yours, ,
ingredients : Benzocaine 20%, Lidocaine 6%, and Tetracaine 4%.
Before starting the treatment, you can apply BLT cream all over
the face and roll the MTS until the anesthetic cream is absorbed
well. Then wrap the patient’s face with plastic wrap for about
10-20 minutes. The patient will feel the numb sensation, includ-
ing his/ her mouth (will feel a little swollen). Don’t forget to put
holes on the wrap for nose and mouth to breath. After that, you
can start apply medication to patient’s face and use MTS Roller If you have any problems or questions related to aesthetic
once again. With BLT cream applied before, patient won't feel medicine, you can e-mail us at: firstname.lastname@example.org,
any pain again. fax us at : (+62)21 3909333/3917373
or send us postmail to: Jl. Kramat VI No. 13. Jakarta Pusat, 10430.
get your own device now!
Automotically adjusted syringe Pneumatic power
pressure depending on the • Painless The pneumatic allows faster injection
viscosity of the product • Economic Sterile Viewfinder:
No product wastage No tremble = No pain as well as faster needle movement.
reduces impact No dripping or waste of medicatio
In the U225 the dripping in betw
injectio ns has been reduced to zero.
Needle syringe separation
• Precise This provides added stability and
Injection speed and frequency less vibration while injecting.
• Product Delivery
Fully variable: Depth adjustment
a dial, shows
Drop by drop or continuous Depth is easily adjustable with
• Light weight • Flexible cted.
Less than 500g Adjustment of needle the user the injection depth sele
from 0 to 10 mm
U225 is the most sophisticated mesotherapy • Celugel: heat-conducting anticellulite active gel based on high-
concentrate biorubina liposomes.
injector curently available on the market.
• Redugel: active reducing and anti-obesity gel. It contains caf-
It is fully automatic, powered by pneumatic feine and ivy extract.
pressure generated by an air compressor. • Firmgel: firming gel containing horsetail herb and ginkgo bi-
ome devices and drugs used for mesotherapy are usually Therma G-Plus
high in price. Understanding this, Medica Persada in co- Therma G-Plus is a multi-function device with dual radio frequency
operation with ADIRA finance offer installment payment system. The radio frequency used affects ion of the molecule forming
program for doctors or other health professional who desires to biologic tissue. The high frequency energy that has been converted
own their own devices. into biothermal energy increases tissue’s temperature, promotes ac-
tivation of cellulation and improves lymph drainage.
We offer you three interesting program: free interest payment,
reasonable interest payment, and first-installment free. You can This device can be used for:
choose any program up to 24 months duration. • Reducing body fat
• Increasing mesotherapy treatment effectiveness
Here are some product lists that you can buy with installment • Skin rejuvenation
system. All you need is to give your complete data and purchas- • Acne and flecks control
ing list to Meso Medica. The process is so easy and you can get • Wrinkle control
your own device in no time. • Pain reducing
• Promoting hair growth by giving an impulsion to the hair fol-
No need to hesitate now. Pick up your phone and contact us. licle
Alamat, nomer telpon, fax, dan email. • Strengthening weak and thin hairs
• Erectile dysfunction
Boks • Urinary incontinence
Thermojet is a thermolipolysis appliance that creates tailor-made iPULSE is a unique device for hair removal and skincare. It works
treatment to each client. It uses infrared waves at 8,000 Ang- through patented way of delivering micro-pulses of intense light.
stroms and the radiation stimulates the metabolism of the adipo- This product is able to deliver light energy efficiently at lower cost. It
cytes and improving circulation. The infra-red energy increases is also able to treat larger skin areas in considerably less time.
body temperature and stimulates body’s chemical and metabolic
reactions. This will cause fat to dissolve. This device can be used for various skin treatments, such as remov-
ing age spots, lesions, uneven pigmentation and thread veins, acne
This device can be used with: treatment, and wrinkel reduction. All of that can be achieved with
swift and remarkable results.
Held in Raflesia Grand Ballroom and Balai Kartini Exhibition Center, September 7-10 2007, Cosmobeaute Seminar Program is the
2nd Indonesia International Exhibition & Conference on Cosmetics, Hair, Beauty & Spa. This event was considered as one of the
biggest event in beauty industry. Attended by 6.254 participants, this events has also increase its number of contributing exhibitors
amount to 260 companies from 25 countries. One of the key speaker in this event was Prof. Yongji Chung, PhD. from PT Aslanindo
Suksestama talking about ‘Fight Against Aging Process with Growth Factors & Peptides Complex’. There were also a demonstration
of New Magic Beauty Plus by Ms. Songja Park (Product Manager of Hwajin Cosmetics-Korea) and a seminar and hair show by Rudy
Hadisuwarno’s Artist Team. Even until the last day, the participants didn’t seem loosing their interest on the exhibitions and confer-
a Better Way to Remain Young!
As time goes by, various physiological changes happened to our body. These include natu-
ral cutaneous aging such as development of wrinkles, skin thinning, colour changes, he-
liodermy, and pigmentary disorders. Antioxidative therapy is one way to stop this process
as mentioned by dr. Alain Gondinet at a workshop held on 26-27 Oktober 2007. Organic
silicon or Silanol is one of the anti free radicals which helps against aging process. In
this workshop was launched Conjonctyl®, a Silanol containing hydrocarbon group and
hydroxyl radicals, both necessary to reach the greatest bioavailability on the body. Unlike
mineral silicon, Silanol has at minimum one atom of carbon linked to one hydrogen (Si-C).
Its’ hydrogen bounds unite the -OH functions to those of the salicylate ensuring the stabil-
ity of the product in aqueous solution. As a structure and components of the connective
tissue extra cellular matrix Silanol works by biosynthesize collagen from a fibroblast. This
workshop was held from 8 to 2 AM and attended by 30 physicians.
MSG damages saraf otak
Narcotics is widely known can cause extreme Nuricafe
damage for brain, there is another substance
cause damage for human being, that substance • Provide healthy food menu, without
calls Monosodium Glutamate (MSG) – food spice MSG
which is known in Indonesia as “vetsin or “micin” . • Nutritionist consultation by dr. Diana Su-
The trade mark varies in market; all of them is pure nardi
“chemical substance” . • Open 9am – 10pm
Researches by experts from all over the world show • International standard of cooks
that MSG can damage children brain. During their
growth period, it damage children neuron system We also provide meeting package for 10 per-
so they have difficulties-emotionally & during their son’s minimum order
study Evidence Based Medicine also proved that
You deserve free facilities of :
this chemical substance can damage part of brain
that controls the hormone permanently. Further-
more it can cause endocrine syndrome. For adult,
all chemical substance that calls excitotoxin is very
bad. It caused epidermy disease such ad Parkin-
son, Huntington, ALS, Alzheimer etc. Contact Person :
Not all know that excitotoxin in food spice cause Didin Kuswara
risks for people who suffer from diabetes, stroke, erpour Nutricafe
brain injury, tumor, meningitis research show hat Oasis Mitra Sarana Apartment Tower C lobby Level
chemical substance can damage the brain function Jl. Kalilio No. 155-157 Senen Raya Jakarta Pusat
he effect can not be cured for children. Telp./ Fax (021) 3524334
22 Grand Launching érpour Kalimalang
venue: Komplek Pusbinal PU Blok B No. 1A 14—19 Training IMMA
Jl. Inspeksi Saluran Kalimalang 21—26 Training IMMA
28 Business Opportunity Launching
érpour med-spa, skin and mesotherapy center
for sub distributor February
venue: érpour nutricafe, OASIS Mitra Sarana Apartement
Tower C Lobby Level 11—16 Training IMMA Jakarta
Jl. Kalilo No. 155-157 Jakarta Pusat 25—1 Training IMMA Jakarta
5—10 Training IMMA
10 Mesotherapy Workshop
Speaker: Dr. Ibarra, Philipine
Aesthetic Medicine and Pain Management
venue: érpour nutricafe, OASIS Mitra Sarana Apartement
Tower C Lobby Level
Jl. Kalilo No. 155-157 Jakarta Pusat
19—24 Training IMMA
International Symposium and Exhibition in
venue: The Ritz Carlton Grand Ballroom Pacific Place, SCBD
25 Aptos Hands on Training
venue: érpour nutricafe, OASIS Mitra Sarana Apartement
Tower C Lobby Level
Jl. Kalilo No. 155-157 Jakarta Pusat
3—8 Training IMMA
7--8 ICAAM ASIA
Revital - Celluform - An Anti-Aging Blow of Wellness
Intercontinental Conference On Anti-Aging &
Innovative formula with phosphatidylcholine and N-acetyl
venue: Everbright Convention & Exhibition Centre the absorption of the adipose stores giving
cysteine that promotes
10—15 Training IMMA the skin a smoother aspect.
Recommended in case of "orange peel" skin.
Full Face Peeling Lip & Eyelid + Easy TCA Chemo-abrasion (Easy TCA) +
Blending Bleaching Cream + Purifying Cream
ONEskinONE peelings & cosmeceutics
Skin Tech has perfected a range of peelings adapted for all skin types
ONLY TOUCH PEEL EASY PHYTIC SOLUTION
[ A DEEP LOCAL TREATMENT ] A surface peeling with a progressive action for patients who do not want re-
Recommended for marks deeply ingrained in the hands or face. moval. It makes the complexion uniform and gives a tensor effect. Treatment
to be repeated once or twice a week. Social life is not affected.
[ A TRUE REJUVENATOR ] EASY TCA
It regenerates the entire structure of the skin. The rejuvenating effect is such [ A GOOD APPEARANCE REDISCOVERED ]
that it can give you five or ten years. It stimulates the making of collagen. This Recommended for the treatment of acne marks and scars, it also gives a spark
peeling involves an interuption of your social life for about five days. to tired skin. It is painless and to be repeated four times (once a week). With no
interruption to your working life it must done at lunch time.
Lip & Eyelid
[ A REJUVENATOR FOR EYES & LIPS ]
Intended to correct deep wrinkles. Expect an interruption to your social life Your Doctor will help in the choice of peeling that is suitable for you according to
of around 8 days. the state of your skin and result desired.
Textbook of Chemical Peels Superficial, Medium and Deep Peels in Cosmetic Practice
This book is the definitive reference for all engaged in chemical peels in cosmetic practice, based on one authors extensive experience
in research, practice and teaching. It contains the result of over 15 years of work with peels and covers all types of treatment and all
types of peel, paying attention to science underlying their use, as well as to preparation, application and potential complications
Available Certified and Accredited Peeling Training for advance
Including Hands On
By Indonesian Medical Mesotherapy Association (IMMA)