ADAM2 Mm.386907 TC − + S Biotin Trypsin −

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A Biotin: Trypsin: Mm.87328 Mm.386907 Mm.157049 ADAM2 − − TC + − − − S + − − + kDa 22 68 35 45 B Mm.87328 Mm.386907 Mm.157049 ADAM2 α-tubulin Head Tail kDa 22 68 35 45 50

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