SPLEEN

SPLEEN Mouse 1 Mouse 2 Mouse 3 Mouse 4 Mouse 5 Mouse 1 Mouse 2 Mouse 3 Mouse 4 Mouse 5 Mouse Mouse Mouse Mouse Mouse 1 2 3 4 5 CFU Strain Strain Strain Strain Strain 1 1 1 1 1 Day 1 Day 2 Day 3 Inoculum 2.77E+05 8.50E+06 2.02E+07 6330.00 2.20E+05 1.10E+07 2.60E+07 2.92E+05 1.00E+07 8.67E+06 3.05E+05 7.33E+06 8.00E+06 3.45E+05 3.32E+06 7.33E+07 2.38E+05 1.58E+05 2.33E+05 2.73E+05 2.05E+05 4.05E+05 2.12E+05 3.23E+05 4.07E+05 3.70E+05 2.75E+06 3.25E+06 3.38E+06 3.12E+06 1.37E+06 1.92E+06 3.67E+06 3.75E+06 3.38E+06 1.93E+06 1.48E+07 2.05E+07 3.37E+06 6.67E+06 5.17E+07 1.23E+07 1.83E+07 2.62E+06 5.00E+06 7.67E+07 6530.00 6450.00 Strain 2 Strain 2 Strain 2 Strain 2 Strain 2 Strain Strain Strain Strain Strain 3 3 3 3 3 Mouse 1 Mouse 2 Mouse 3 Mouse 4 Mouse 5 Mouse Mouse Mouse Mouse Mouse 1 2 3 4 5 Strain 4 Strain 4 Strain 4 Strain 4 Strain 4 Total Total Total Total Total CFU CFU CFU CFU CFU 9.20E+05 5.90E+05 8.48E+05 9.85E+05 9.20E+05 1.32E+07 1.79E+07 1.71E+07 1.38E+07 6.62E+06 4.73E+07 6.48E+07 1.47E+07 1.97E+07 2.02E+08 19310.00 32.78 33.40 33.82 0.00 Percentage Day 1 Day 2 Day 3 Strain 1 30.07 64.56 42.61 Strain 1 37.29 61.40 40.10 Strain 1 34.38 58.37 59.16 Strain 1 30.96 53.01 40.68 Strain 1 37.50 50.13 36.36 Strain 2 Strain 2 Strain 2 Strain 2 Strain 2 Strain Strain Strain Strain Strain 3 3 3 3 3 25.91 26.84 27.50 27.75 22.28 44.02 35.88 38.11 41.29 40.22 0.00 0.00 0.00 0.00 0.00 20.89 18.14 19.75 22.53 20.65 14.56 20.47 21.89 24.46 29.22 0.00 0.00 0.00 0.00 0.00 31.34 31.62 22.98 33.90 25.62 26.06 28.28 17.86 25.42 38.02 0.00 0.00 0.00 0.00 0.00 Strain 4 Strain 4 Strain 4 Strain 4 Strain 4 Total inoculum Ratio Strain 1 Ratio Strain 2 Ratio Strain 3 Ratio Strain 4 RVR Strain Strain Strain Strain Strain Day 1 1 1 1 1 1 0.92 1.14 1.05 0.94 1.14 0.78 0.80 0.82 0.83 0.67 1.30 1.06 1.13 1.22 1.19 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! Day 2 1.97 1.87 1.78 1.62 1.53 0.63 0.54 0.59 0.67 0.62 0.43 0.61 0.65 0.72 0.86 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! Day 3 1.30 1.22 1.80 1.24 1.11 0.94 0.95 0.69 1.01 0.77 0.77 0.84 0.53 0.75 1.12 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! Day 1 Mouse Mouse Mouse Mouse Mouse Mean StDev t 1 2 3 4 5 One sample T-test 1 vs 2 0.14 0.33 0.23 0.11 0.48 Strain 2 Strain 2 Strain 2 Strain 2 Strain 2 Strain Strain Strain Strain Strain 3 3 3 3 3 p-value 0.26 0.15 3.87 0.01795 1 vs 2 Day 2 Mouse Mouse Mouse Mouse Mouse Mean StDev t 1 2 3 4 5 1.34 1.33 1.19 0.94 0.91 Strain 4 Strain 4 Strain 4 Strain 4 Strain 4 p-value 1.14 0.21 12.34 0.00025 1 vs 2 Day 3 Mouse Mouse Mouse Mouse Mouse Mean StDev t 1 2 3 4 5 0.36 0.28 1.12 0.23 0.34 p-value 0.46 0.37 2.82 0.04783 ne sample T-test 1 vs 3 -0.38 0.08 -0.08 -0.28 -0.05 2 vs 3 -0.53 -0.26 -0.30 -0.39 -0.52 1 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 2 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 3 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! -0.14 0.19 1.70 0.16360 1 vs 3 1.54 1.27 1.13 0.89 0.67 -0.40 0.12 7.27 0.00190 2 vs 3 0.19 -0.06 -0.06 -0.05 -0.25 #DIV/0! #DIV/0! #DIV/0! #DIV/0! 1 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 2 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 3 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 1.10 0.34 7.30 0.00187 1 vs 3 0.53 0.39 1.28 0.49 -0.01 -0.04 0.16 0.62 0.56792 2 vs 3 0.17 0.11 0.16 0.26 -0.36 #DIV/0! #DIV/0! #DIV/0! #DIV/0! 1 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 2 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 3 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 0.53 0.47 2.55 0.06341 0.07 0.24 0.63 0.56351 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! LIVER Mouse 1 Mouse 2 Mouse 3 Mouse 4 Mouse 5 Mouse 1 Mouse 2 Mouse 3 Mouse 4 Mouse 5 Mouse Mouse Mouse Mouse Mouse 1 2 3 4 5 CFU Strain Strain Strain Strain Strain 1 1 1 1 1 Day 1 Day 2 Day 3 Inoculum 7.00E+04 1.19E+06 6.35E+07 6330.00 3.34E+04 1.69E+06 8.65E+07 2.60E+04 3.02E+06 5.65E+06 6.85E+04 1.77E+06 1.05E+07 9.85E+04 3.19E+05 1.17E+08 8.50E+04 4.04E+04 2.74E+04 7.50E+04 7.85E+04 8.00E+03 1.85E+04 2.25E+04 1.15E+04 1.07E+04 1.02E+06 1.70E+06 5.50E+05 1.19E+06 8.00E+04 1.70E+05 2.00E+05 3.87E+05 1.99E+05 2.30E+04 1.87E+07 2.00E+07 3.15E+06 2.84E+06 2.10E+07 5.00E+06 6.15E+06 1.05E+06 5.85E+05 1.34E+07 6530.00 6450.00 Strain 2 Strain 2 Strain 2 Strain 2 Strain 2 Strain Strain Strain Strain Strain 3 3 3 3 3 Mouse 1 Mouse 2 Mouse 3 Mouse 4 Mouse 5 Mouse Mouse Mouse Mouse Mouse 1 2 3 4 5 Strain 4 Strain 4 Strain 4 Strain 4 Strain 4 Total Total Total Total Total CFU CFU CFU CFU CFU 1.63E+05 9.22E+04 7.59E+04 1.55E+05 1.88E+05 2.37E+06 3.59E+06 3.95E+06 3.15E+06 4.22E+05 8.72E+07 1.13E+08 9.85E+06 1.39E+07 1.51E+08 19310.00 32.78 33.40 33.82 0.00 Percentage Day 1 Day 2 Day 3 Strain 1 42.94 50.00 72.86 Strain 1 36.17 47.00 76.79 Strain 1 34.28 76.30 57.36 Strain 1 44.19 56.06 75.43 Strain 1 52.49 75.56 77.23 Strain 2 Strain 2 Strain 2 Strain 2 Strain 2 Strain Strain Strain Strain Strain 3 3 3 3 3 52.15 43.76 36.06 48.39 41.83 4.91 20.07 29.66 7.42 5.68 0.00 0.00 0.00 0.00 0.00 42.83 47.42 13.92 37.64 18.98 7.17 5.58 9.78 6.30 5.46 0.00 0.00 0.00 0.00 0.00 21.40 17.75 31.98 20.37 13.92 5.74 5.46 10.66 4.20 8.85 0.00 0.00 0.00 0.00 0.00 Strain 4 Strain 4 Strain 4 Strain 4 Strain 4 Total inoculum Ratio Strain 1 Ratio Strain 2 Ratio Strain 3 Ratio Strain 4 RVR Strain Strain Strain Strain Strain Day 1 1 1 1 1 1 1.31 1.10 1.05 1.35 1.60 1.56 1.31 1.08 1.45 1.25 0.15 0.59 0.88 0.22 0.17 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! Day 2 1.53 1.43 2.33 1.71 2.31 1.28 1.42 0.42 1.13 0.57 0.21 0.16 0.29 0.19 0.16 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! Day 3 2.22 2.34 1.75 2.30 2.36 0.64 0.53 0.96 0.61 0.42 0.17 0.16 0.32 0.12 0.26 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! Day 1 Mouse Mouse Mouse Mouse Mouse Mean StDev t 1 2 3 4 5 One sample T-test 1 vs 2 -0.25 -0.21 -0.03 -0.10 0.35 Strain 2 Strain 2 Strain 2 Strain 2 Strain 2 Strain Strain Strain Strain Strain 3 3 3 3 3 p-value -0.05 0.24 0.46 0.67149 1 vs 2 Day 2 Mouse Mouse Mouse Mouse Mouse Mean StDev t 1 2 3 4 5 0.24 0.01 1.91 0.58 1.74 Strain 4 Strain 4 Strain 4 Strain 4 Strain 4 p-value 0.90 0.87 2.30 0.08267 1 vs 2 Day 3 Mouse Mouse Mouse Mouse Mouse Mean StDev t 1 2 3 4 5 1.58 1.81 0.79 1.69 1.94 p-value 1.56 0.45 7.75 0.00149 ne sample T-test 1 vs 3 1.16 0.51 0.17 1.13 1.43 2 vs 3 1.42 0.72 0.20 1.23 1.08 1 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 2 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 3 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 0.88 0.52 3.77 0.01960 1 vs 3 1.31 1.27 2.04 1.52 2.14 0.93 0.48 4.32 0.01241 2 vs 3 1.07 1.25 0.13 0.94 0.41 #DIV/0! #DIV/0! #DIV/0! #DIV/0! 1 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 2 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 3 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 1.66 0.41 9.06 0.000822 1 vs 3 2.05 2.18 1.43 2.18 2.09 0.76 0.47 3.59 0.02305 2 vs 3 0.47 0.37 0.64 0.49 0.16 #DIV/0! #DIV/0! #DIV/0! #DIV/0! 1 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 2 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 3 vs 4 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! 1.99 0.31 14.15 0.00014 0.42 0.18 5.29 0.00612 #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0! #DIV/0!