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					A Presentation to the
University of Nebraska
Medical Center
Federal Funding Opportunities Workshop




                            The Implementation Group, Inc.
                                    December 13-14, 2005
Outline
 Overview and Objectives
 Federal R&D Overview
 UNMC R&D Analysis
 Federal Funding Opportunities
       • The National Science Foundation
       • National Aeronautics and Space Administration
       • Department of Energy
   Merit Review and Proposal Development
TIG Overview
The Implementation Group, Inc. (TIG)
   TIG is a full-service consulting firm that
   assists educational institutions,
   organizations and corporate entities to target,
   capture and implement U.S. government and
   private sector contracts and grants.

         • Established: 1994
         • Location: Washington, DC
TIG: Services
TIG’s service offerings are focused on the full life cycle of activities
associated with being successful in the federal grants and contracts
arena. They include:
         Capability Assessments and Strategic Planning
         Intelligence Gathering
         Opportunity Identification and Qualification
         Partnership Formation
         Liaison with federal officials and private sector funders
         Proposal Development and Proposal Enhancement
         Project Implementation
         Troubleshooting
TIG Partnership with the UNMC
UNMC/TIG Partnership
 To assist UNMC to increase its competitiveness for
 federal research and training grants, with emphasis on
 non-NIH funding. Areas of work:
     • Assessment and Analysis
         • Conduct SWOT analysis
     • Infrastructure Improvement
     • Agency Assistance/Opportunity Identification
         • Identify and assist UNMC in pursuing federal grant opportunities
           particularly at the NSF
     • Proposal review and development
     • Project implementation assistance
Visiting Team
   The Implementation Group, Inc.
       • Joseph G. Danek, Ph.D.
          Senior Vice President and Chief Operating Officer
       • Jennifer C. Danek, M.D.
          Consultant

   National Science Foundation
       • Christopher Greer, Ph.D.
          • Program Director, Frontiers in Integrative Biological Research
            (FIBR), Directorate for Biological Sciences
Specific Goals of Visit
   Review federal funding opportunities at the NSF, DOE, and
    NASA particularly in the life sciences
   Learn more about UNMC R&D capabilities and priorities

   Identify (with faculty) the strengths and weaknesses in
    obtaining funding
   Match funding opportunities to interests of faculty groups
   Develop a preliminary proposal development plan
   Assist UNMC in executing plan
Current Climate
Key Budget and Economic Points
The Recent Past
 To date, the United States has allocated $351 billion for military
  operations, security and reconstruction costs in Iraq and
  Afghanistan.
 The U.S. Congress approved roughly $70 billion in emergency
  spending for disasters.
The Immediate Future
 The FY2006 Defense Appropriations Bill contains an additional $50
  billion for military operations, security and reconstruction costs in
  Iraq and Afghanistan.
 There is an additional $100–200 billion in emergency spending for
  the recent disasters.
 “Baby Boom” retirement era will give rise to much larger annual
  Medicare expenditures.
 Escalating costs associated with maintaining the Federal debt.
                                            Spending America’s Income
              Broad revenue and spending categories in President Bush’s fiscal 2005 budget:

        Where it comes from (receipts)                           How it would be spent (outlays)
        $2.1 trillion                                                               $2.4 trillion
                                                                             $420 billion: National defense
                                                                                    (discretionary)

           Individual income tax:
               $874 billion
                                                                             $490 billion: Discretionary
                                                                                           (non-defense)

           Corporate income tax:
               $230 billion
                                                       $2.4
                                                      trillion               $510 billion: Social Security


                 Payroll tax:
                $794 billion
                                                                             $290 billion: Medicare


                                                                             $178 billion: Interest on debt
           Excise tax: $73 billion
 Estate and gift tax: $21 billion                                            $188 billion: Medicaid
    Customs duties: $22 billion
             Other: $37 billion
                                                                             $320 billion: Other
    Deficit: $345-$360 billion
(with adjustment for revenue uncertainty)
Development of the Federal R&D Budget
                                            Showing Fields of Science and Executive and Legislative Decision Units
                                                   Connecting lines indicate location of agency budget decisions, but not decision sequences.

                                                  National Science                                                                                                                        House and
                                                   and Technology                                  House & Senate                   Senate                   House                          Senate
  Fields of     Departments                       Council Research         Budget Review         Budget Committees               Authorization            Authorization                 Appropriations
  Science        & Agencies                          Committees            Offices (OMB)         (Budget Functions)               Committees               Committees                   Subcommittees
                                                                                                                                                                                        (With significant R&D $)
                                                                                                             National
                                                                                  National                   Defense
                                                                                 Security &
 Engineering
                 Agency for International                                      International
                      Development       Defense                                    Affairs                 International            Armed Services            National Security                   Defense
                                                                                                             Affairs
                                                     Environment and
  Physical             Energy                             Natural                                    General Science, Space        Foreign Relations            International                    Foreign
  Sciences                                              Resources                                        & Technology                                             Relations                     Operations


                      Interior
                                                                                 Natural                                            Energy & Natural             Commerce                       Energy and
                                                                                                                                                                                                  Water
   Math &                                                                      Resources,                    Energy                    Resources
                                                                                                                                                                                               Development
  Computer         Agriculture                                                 Energy, and
                                                      International              Science                                                                          Resources
   Science                                              Science,                                                                     Environment &
                                                                                                       Natural Resources &
                        NASA                         Engineering and                                      Environment                 Public Works                                                Interior
                                                       Technology                                                                                              Transportation &

Environmental            NSF                                                                                                                                    Infrastructure
                                                                                                                                  Commerce, Science,
  Sciences                                                                                                 Agriculture
                                                                                                                                   & Transportation
                                                                                                                                                                                               Commerce,
                         NRC                                                                                                                                       Science                    Justice, State,
                                                                                                                                                                                                Judiciary

                         EPA
                                                                                                      Commerce & Housing
    Life                                            National Security                                      Credit                     Agriculture,                                            Agriculture &
                   Commerce                                                                                                                                      Agriculture
  Sciences                                                                                                                        Nutrition, & Forestry                                      Related Agencies


                                                                               Economics &                Transportation                                                                       VA-HUD-Inde-
                 Transportation                                                Government
                                                                                                                                   Banking, Housing
                                                                                                                                                          Banking & Financial Affairs            pendent
                                                                                                                                    & Urban Affairs                                              Agencies
 Psychology
                Housing &Urban                           Science                                     Community & Regional
                                                                                                        Development
                 Development                                                                                                       Labor and Human               Economic &                  Transportation &
                                                                                                                                       Resources                 Educational                 Related Agencies
                                                                                                                                                                Opportunities
                                                                                                       Education, Training,
   Social           Education                                                                         Employment, & Social
                                                                                                            Services
  Sciences                                                                                                                          Veterans Affairs           Veterans Affairs
                                                                                                                                                                                             Labor, Health &
                                                                                                                                                                                            Human Services, &
                Health & Human                         Technology                                                                                                                               Education
                    Services                                                                                 Health
                                                                                  Human
   Other                                                                        Resources,                                             Judiciary                  Judiciary
  Sciences             Labor
                                                                               Veterans, and           Veterans Benefits &
                                                                                   Labor                    Services


                      Justice
                                                                                                     Administration of Justice
                    Veterans
                     Affairs
R&D in the FY 2006 Budget
       Total R&D by Agency: FY 2006 Proposed
       Budget Authority in billions of dollars   All
                                           DHS
                                       USDA    Other
                                    NSF 2% 1% 4%
                                    3%
                          DoE
                          6%


                  NASA
                   9%


                                                                  DoD
                                                                  53%



                    HHS (NIH)
                      22%


Source: AAAS, based on OMB R&D Budget Data and agency estimates
R&D in the FY 2006 Budget
   Federal R&D at all-time high of $132 billion this year, but
    would barely increase (0.1%) in 2006.
   In FY 2006, federal research funding would fall 1.4 percent
    to $54.9 billion
   The FY 2006 budget represents a downward shift from
    recent trends
   Cuts across the federal R&D portfolio
   NSF: most research directorates would stay flat for three
    years. Steep cuts proposed to education programs.
   NIH: budget would increase just 0.5 percent. RPG success
    rate would fall to 21 percent.
   USDA: boosts for competitive grants, but cuts to formula
    funds.
FY 2006 R&D Appropriations (as of 11/05)
Other Agency Funding for Life Sciences:
$4.3B (14% of total budget) in 2005


                                  Life Sciences Portfolio,
                                   Total - $29 billion
              7%
     22%                          HHS – 86% (25.5 billion)
                    16%
                                  Other – 14% ($4.3 billion)
                                    -   USDA – 34% ($1.4B)
                          8%
                                    -   NSF – 13% ($578M)
                                    -   DoD – 16% ($695M)
     34%           13%              -   DoE – 7% ($289M)
                                    -   NASA – 8% ($334M)
                                    -   Other – 22% ($953M)
 “Life Sciences” Research Dollars as
 Percentage of Total Agency Budget: $29.8B
100%

90%

80%

70%

60%
                                                                            Total Budget
50%
                                                                            Life Sciences

40%

30%

20%

10%

 0%
       HHS   DoE   DoD   NASA          NSF         USDA         Other



                         Source: http://www.nsf.gov/statistics/infbrief/nsf06300/tab4
UNMC R&D Portfolio
       UNMC - Federal obligations for science and engineering research and
       development (R&D) to universities and colleges, by state, institution, and
       agency: FY 2002 [ dollars in thousands],


                                                                          DoD1


                                                                                  Development
          State and institution   Total      AID Com Total         Research                             DOE ED EPA          HHS       Int NASA NSF USDA

                                                                                Advanced   Major
                                                                               technology systems

Nebraska, total                     91,398 1,600     51   10,860       2,748        2,519       5,593 2,689 144 870         51,091 1,130 1,128 10,771 11,064


 Creighton U.                        5,718      0     0        0           0            0           0    655     0     0      4,691     0   122       0      250

   U. NE Medical Ctr.             35,944       0     0 2,946           427        2,519           0       0      0     0 32,881        0     0 117            0
 U. NE Lincoln                      45,170   1,600   37    7,914       2,321            0       5,593      0     0    870    12,514   965   306   10,175   10,789
 U. NE Omaha                         2,770      0    14        0           0            0           0    730     0     0       805     42   700     479        0
 U. NE central administration        1,796      0     0        0           0            0           0   1,304   144    0       200    123    0        0       25


UNMC Percent Share of State          39%     0% 0%         27%         16%         100%          0%      0% 0% 0%            64%      0%    0%     1%       0%




Source: National Science Foundation, Division of Science Resources Statistics, Federal Science and Engineering Support to
Universities, Colleges, and Nonprofit Institutions: Fiscal Year 2002 (Table B-17): Arlington, VA (NSF 05-309) [March 2005]
       UNMC as Percentage of Total State Fed.
       Obligation for S&E R&D
        100%
         90%
         80%
         70%                                                                 64%
         60%
         50%                                                                                                                             UNMC
         40%       39%

         30%                                 27%
         20%
         10%                                                  0%                               0%                 1%
                                                      0%
          0%               0%       0%
                  TOTAL    USDA     COM      DOD     DOE      EPA             HHS              NASA               NSF

In FY 2002, Nebraska had no ARC, DoT, HUD, Labor, NRC, OJP, or SSA funding.
                                                                   National Science Foundation, Division of Science Resources Statistics, Federal Science
                                                                   and Engineering Support to Universities, Colleges, and Nonprofit Institutions: FY 2000
                                            Fed. Obligations for R&D – All Agencies
                                     3.00




                                     2.50
Value (normalized to 1.00 in 1995)




                                     2.00




                                                                                                                  UNMC
                                     1.50
                                                                                                                  All Institutions




                                     1.00




                                     0.50




                                     0.00
                                            1993   1994   1995   1996   1997   1998   1999   2000   2001   2002
                                            Fed. Obligations for R&D - NIH
                                     3.00




                                     2.50
Value (normalized to 1.00 in 1995)




                                     2.00




                                                                                                                   UNMC
                                     1.50
                                                                                                                   All Institutions




                                     1.00




                                     0.50




                                     0.00
                                             1993   1994   1995   1996   1997   1998   1999   2000   2001   2002
                                             Fed. Obligations for R&D - DoD
                                     16.00

                                     15.00

                                     14.00

                                     13.00

                                     12.00
Value (normalized to 1.00 in 1995)




                                     11.00

                                     10.00

                                      9.00
                                                                                                                   UNMC
                                      8.00
                                                                                                                   All Institutions
                                      7.00

                                      6.00

                                      5.00

                                      4.00

                                      3.00

                                      2.00

                                      1.00

                                      0.00
                                             1993   1994   1995   1996   1997   1998   1999   2000   2001   2002
       Fed. Obligations for R&D - NSF
3.00




2.50




2.00



                                                                                                     UNMC
1.50
                                                                                                     All Institutions



1.00




0.50




0.00
       1993   1994   1995   1996          1997            1998           1999   2000   2001   2002
                                   Value (norm alized to 1.00 in 1995)
                                        UNMC Federal Obligations for R&D
                                     $3,500                                                                                      $35,000



                                     $3,000                                                                                      $30,000
$ (Thousands) - All Other Agencies




                                     $2,500                                                                                      $25,000                         DOD
                                                                                                                                                                 DOEd




                                                                                                                                           $ (Thousands) - NIH
                                                                                                                                                                 HHS-CDCP
                                     $2,000                                                                                      $20,000
                                                                                                                                                                 HHS-HRSA
                                                                                                                                                                 HHS-Other
                                                                    NIH (right axis)
                                                                                                                                                                 DOI
                                     $1,500                                                                                      $15,000
                                                                                              DOE (left axis)
                                                                                                                                                                 NASA
                                                                                                                                                                 NSF
                                     $1,000                                                                                      $10,000                         HHS-NIH



                                      $500                                                                                       $5,000



                                        $0                                                                                       $0
                                              1993   1994   1995   1996         1997   1998   1999          2000   2001   2002
Summary Analysis (1993 – 2002)
   Overall Growth: UNMC overall federal R&D growth
    outpaced growth across all institutions

   NIH: UNMC federal R&D is dominated by NIH (85% - 95%
    of total)

   DoD: UNMC shows sporadic peaks in DoD but no
    consistent growth despite DoD growth across all
    institutions

   NSF: UNMC shows no consistent growth patterns at NSF
Comparison to Peer Institutions
                                                                            Normalized Total R&D Expenditures
                                                                      (Total R&D Expenditures / FT graduate students)
                                                                among institutions with similar numbers of graduate students
                                                                                          (2002 data)
                                        $1.00


                                                                                                                                                 $167m

                                                                                                                                                   174
                                        $0.80
  $ (million per FT graduate student)




                                                                                                                           $132m
                                        $0.60

                                                                                                                            193



                                        $0.40

                                                                            $71m                  $103m


                                                                             177                   250

                                        $0.20         $45m

                                                       177


                                        $0.00
                                                U. Arkansas Health    U. Nebraska Medical   Thomas Jefferson U.   Medical U. South Carolina   Rockefeller U.
                                                  Science Center            Center
Comparison to Peer Institutions cont.
                                              Federally Financed Academic R&D Expenditures (2003)

                 $400,000



                 $350,000



                 $300,000



                 $250,000
 $ (thousands)




                 $200,000



                 $150,000



                 $100,000



                  $50,000



                      $0
                             Medical     U. Nebraska U. Arkansas    Medical U.   U. Texas    Mount Sinani    Oregon       Baylor      U. California-
                            College of      Medical   for Medical     South       Medical     College of     Health      College of       San
                              Ohio          Center     Sciences      Carolina    Branch at    Medicine      Sciences     Medicine      Francisco
                                                                                 Galveston                  University
Conclusion
  The Pot 'O Gold!
                     Opportunities exist
                     for UNMC at NSF,
                     DoE, NASA, and
                     other agencies
National Aeronautics and Space
                Administration
FY 06 NASA By The Numbers
 Total: $16.4 billion (+ 1.3%)
 R&D: $11.5 billion (+ 7.3%)
 Science, Aeronautics, and Exploration (SAE):
  $9.7 billion (+7.6%)
 Biological/Life Sciences: $500 million (est.)
Cuts to NASA’s Research Portfolio
   Aeronautics research portfolio:
     - down 2.5 percent to $938 million
   Earth Sciences:
     - down 7.3 percent to $2.1 billion
   Biological and Physical Sciences:
     - down 13.6 percent to $799 million
     - NASA is dramatically restructuring and downsizing its
       biological and physical sciences research portfolio into
       a Human Systems Research and Technology program
       more narrowly focused on research topics relevant to
       human space flight.
OBPR Headquarters Organizational Chart
OBPR Enterprise Strategy

    Five organizing questions are the basis for the Biological
     and Physical Research Enterprise Strategy:
     1.   How can we assure the survival of humans traveling far from Earth?
     2.   How does life respond to gravity and space environments?
     3.   What new opportunities can research bring to expand understanding
          of the laws of nature and enrich lives on Earth?
     4.   What technology must we create to enable the next explorers to go
          beyond where we have been?
     5.   How can we educate and inspire the next generation to take the
          journey?
    Biological/Life Sciences Research
   Estimated budget: $400 million in FY06
   Supports safe human presence in space
   Research to control space flight risks to humans from
    radiation, reduced gravity, and isolation
   Pursues fundamental biological questions from cell to
    tissues to organisms to ecosystems which produce
    results that support
        • Methods enabling human explorations of space;
        • Understanding of biological systems; and
        • Improving human health on Earth
  Fundamental Space Biology Division
Goals:
   Use microgravity and other space effects to enhance
    understanding of biological processes
   Develop foundation of biological knowledge

Research Elements:
  Molecular structures and physical interactions,
   Molecular biology, Cell biology, Evolutionary
   biology, Gravitational biology, Developmental
   biology, Organismal and comparative biology
Bioastronautics Research Division
Goals:
 Set priorities for issues related to flight crew health and med.
  technology, and fundamental and applied research
 Sponsor research to address flight medical safety and performance
  issues
 Integrate science and medical research

Research Elements:
 Space Biomedical Research Areas: Biomedical physiology,
  Behavior and performance, Group dynamics, Radiobiology, Space
  and human factors engineering, Space medicine, Flight crew health
  care delivery and systems, Human clinical and space medical
  research
 Spacecraft Habitability, Planetary Habitat, Environmental Health, and
  Space Systems Technology: Advanced life support, Toxicology,
  microbiology, Advanced EVA , Radiation protection, Bioplex
 This division also manages the National Space Biomedical Research
  Institute: Countermeasures development
Office of Health and Medical Systems

                 Dr. Richard S. Williams Biography
                Space and Life Sciences Directorate
            Bioethics and Transition to Practice Division

                       Mission for Health Care
  The Chief Health and Medical Officer assists the Administrator to
 ensure the health and safety of NASA employees in space and on
 the ground.

  The Chief Health and Medical Officer also monitors human and
 animal research and clinical practice.
Department of Energy
DoE FY 2006 Budget
 Final DOE budget at $8.7 billion for R&D
  activities, a slight increase of 0.9 percent
 DOE’s Office of Science receives a modest
  0.6 percent increase in its R&D portfolio to
  $3.4 billion includes $130 million in
  congressional earmarks and a boost in
  computing research.
DOE Organizational Chart
DoE Office of Science
 Flat budget for the last decade
 Director’s mission is to secure additional funding and
support
 Primary source of support for the Physical Sciences
       42% of federal support to physical sciences
       Primary support to: high energy physics, nuclear physics,
        nuclear medicine, heavy element chemistry, plasma physics,
        and magnetic fusion, and catalysis
       Manages multidisciplinary science programs
       Directly supports 23, 400 Ph.D.s, Post Docs, and Graduate
        students
   Constructs and operates large scientific facilities
Office of Science’s Biological and
Environmental Research (BER) Program
   Advancing environmental and biomedical knowledge
   Supports fundamental research in:
      Climate change
      Environmental remediation
      Genomics
      Systems biology
      Radiation biology
      Medical Sciences
   Supports leading edge research facilities across a range of
    disciplines
   Coordinates research across all programs
Biological and Environmental Research
(BER) Long-Term Goals
   Life Sciences:
       Characterize the multi protein complexes involving a
        scientifically significant fraction of a microbe’s proteins.
       Develop computational models to direct the use and design of
        microbial communities to clean up waste, sequester carbon, or
        produce hydrogen
   Medical Applications and Measurement Science:
       Develop intelligent biomimetic electronics that can both sense
        and correctly stimulate the nervous system
Office of Science’s Biological and
Environmental Research (BER) Staff
Dr. Aristides Partinos, Associate Director, BER
and Acting Director, Life Sciences Division
   301-903-5051
   ari.partinos@science.doe.gov

Dr. Mike Viola, Director, Medical Sciences
Division
   301-903-0567
   Michael.viola@science.doe.gov
Office of Science’s Biological and Environmental
Research (BER) Merit Review System
    All projects undergo regular peer review and
     evaluation
    Provides independent assessment of scientific
     and/or technical merit of the research
    Basic Review Standards
        Sufficient technical/scientific content and merit
        Completeness
        Program policy and priorities
Summary: Trends in Federal R&D over the
Last Decade
 Big science has hit the life sciences
 All scientific fields are now clearly inter-dependent
 No longer such a thing as “disciplinary science”
 Technology is now driving science, more than the
  reverse
 Significant increases in new term not likely
The Implementation Group, Inc.
 101 Constitution Avenue, NW
        Suite 650 East
    Washington, DC 20001
      202.639.0671 – tel
      202.639.0713 – fax

				
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