Documents
Resources
Learning Center
Upload
Plans & pricing Sign in
Sign Out

Effect of Calcitonic Gene Related Peptide on Lymphatic Vessels

VIEWS: 8 PAGES: 1

									           Effect of Calcitonin Gene-Related Peptide
                      on Lymphatic Vessels
                 V. A. Akopyan, N. V. Balashov, and G. F. Khanipov
  Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences,
                                      St. Petersburg, Russia
                                      Received August 4, 1997

Abstract—The effects of human α-calcitonin gene-related peptide (CGRP) on collecting lymphat-
ic vessels of the rat small intestine mesentery and on an isolated preparation of the thoracic part of
the rat thoracic duct were investigated. The effect of α-CGRP on the lymphatic vessels was shown
to be dose-dependent. This peptide at concentrations of 100 nmole/ml in vivo and 1 µmol/ml
in vitro stimulates the motor activity of lymphatic vessels, increasing phasic and tonic contrac-
tions.

								
To top