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Risk Assessment Guidelines - Department of Chemistry

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Risk Assessment Guidelines - Department of Chemistry Powered By Docstoc
					                                                                                                                            Experiment-Based Risk Assessment Form
     Name of Department                                                      Chemistry                                         Location of Lab                                                                            S5-05-10
     Name of Laboratory                                                    Synthetic Lab                                       Name of PI                                                  A/P Tan Choon Hong/Asst. Prof Zeng Huaqiang

     Name of LO                                                              Yeo Boon Hee                                      Name of Activity/Experiment                                          Expt 6 Preparation of 1,2,3-triphenylcyclopropenium bromide

                                                1. Hazard Identification                                                                                                                                                                                          3. Risk Control
No   Description/Details of Steps in Activity Hazards                                    Possible Accident / Ill Health &           Existing Risk Control (Mitigation)          Severity      Likelihood      Risk Level      Additional Risk Control                   Person Responsible     By (Date)
                                                                                         Persons-at-Risk                                                                                      (Probability)
 1   Addition of reactants into RBF:            Potatssium tert-butoxide and             1) Injury from broken glass           1) Visual inspection of glassware before              2              2                4        (1) Training and communication. GTA and Teaching staff         Ongoing
     (1) Diphenylacetylene.                     Benzal chloride:                         2) Exposure to highly toxic,          use          2) Proper PPE to be worn
     (2) Potassium tert-butoxide (harmful;      1) May cause eye irritation and          highly corrosive and highly           3) Kept away from ignition source
     corrosive).                                possible damage.                         flammable solvent.                    4) Reaction to be performed in the
     (3) Toluene (highly flammable, irritant,   2) Causes skin irritation.               3) Injury from broken syringe and     fumehood
     harmful).                                  3) Causes respiratory tract              needle.
     (4) Benzal chloride (highly toxic and      irritation. Toxic if inhaled.
     corrosive).                                4) Chemical dangerous for
     Introduce chemical via a syringe.          environment.
     The reaction mixture reflux for 3 hrs.     Toluene: Highly flammable

 2   Extraction with water                      1) Caused skin irritation                Exposure and inhalation of toxic 1) Proper PPE to be worn                                   1              2                2                                                                       Ongoing
                                                2)Causes respiratory tract irritation.   chemical                         2) Extraction to be done in the fumehood
                                                Toxic if inhaled
 3   Extraction with Ether (highly              1) Flammable                             1) Exposure and inhalation of         1) Avoid inhalation                                   1              2                2                                                                       Ongoing
     frammable)                                 2) Caused skin irritation                solvent vapor                         2) Proper PPE to be worn
                                                3)Causes respiratory tract irritation.   2) Exposure to flammable              3) Extraction to be done in the fumehood
                                                Toxic if inhaled                         chemicals                             4) Kept away from ignition source

 4   Dry the filtrate using MgSO4 and           MgSO4 May irritate eyes and              1) Exposure and inhalation of         1) Proper PPE to be worn                              1              2                2                                                                       Ongoing
     filtration                                 respiratory tract.                       solvent vapor                         2) Drying to be done in the fumehood
                                                                                         2) Exposure to fine particles
 5   Addition of HBr (in Acetic acid) to the    1) Severe burns, irritating to eyes,     1) Severe burns, irritating to        1) Proper PPE, gloves                                 2              2                4        (1) Training and communication.                                Ongoing
     filtrate. HBr (32% in acetic acid):        irritating to the respiratory system     eyes, irritating to the respiratory   2) Addition of HBr to be done in the
     Corrosive, Flammable                       1) Exposure to chemical                  system           2) Exposure to       fumehood
                                                (corrosive) and solvent                  flammable solvent          3)
                                                2) Flammable solvent                     Exposure to toxic vapors

 6   Filtration of the product                  1) Exposure to chemical                  1) Severe burns, irritating to        1) Proper PPE                                         2              2                4                                                                       Ongoing
                                                (corrosive) and solvent                  eyes, irritating to the respiratory   2) Gloves to be worn
                                                2) Flammable solvent                     system           2) Exposure to
                                                                                         flammable solvent          3)
                                                                                         Exposure to toxic vapors

 7   Analysis using UV-vis and FTIR             1) Exposure to chemical and              1) Exposure to chemicals              Proper PPE to be worn                                 1              2                2                                                                       Ongoing
                                                solvent          2) Exposure to          2) Exposure to solvent vapors
                                                solvent vapors
                                                                                                                                                                                                                     0

                        Conducted By                                                                                                                    Approved By
                                                                                                                                                                         Name
   Signature

Approval date   Next Revision date
                (Maximum 3 years)
                                              Likelihood
                       Likely              Possibly      Unlikely
Cosequence


             Low            3                      2                                 1

             Med            6                      4                                 2

             High           9                      6                                 3

                    Likelihood
                                                                  Remotely possible, combination of
                1 Unlikely                                        factors would be required to trigger
                                                                  the incident (> 10 years)
                                                                  Could happen when additional factors
                2 Possible                                        are reset but otherwise unlikely to
                                                                  occur (last 3 years)
                                                                  Happen all the time, almost inevitable
                3 Very Likely
                                                                  (last 6 months)

                    Consequence
                1 Low                                             Minor Injuries (First Aid), Fire etc.
                2 Medium                                          Hospitilisation, Medical Leave etc
                3 High                                            Serious injuries, Fatality

                    Consequences - Consider the magnitude/severity of the consequences of the Risk Factor occurring and
                    Consequences normally will not change unless there is a physical change to the equipment or process.




                    Likelihood - Team should rely upon their experience and consider realistic scenarios. Listed below are e
                    - Past experience / incidents
                    - Complexity of the activity
                    - Number of personnel involved in the activity (e.g. all personnel, a limited number of trained personnel, e
                    - Frequency of use or execution
                    - Degree of control (involvement of contractors)
                    - Strength/completeness of administrative controls
                    - Sufficiency/formality of training
                    - Other....
                                                              RISK                       DECISION PROCESS


                                                                 <3                        RISK ACCEPTABLE



                                                                 3, 4          CONSIDER ADDITIONAL RISK CONTROL



                                                                 >4            ADDITIONAL RISK CONTROL REQUIRED




 of the Risk Factor occurring and then list this as 3 (High), 2 (Moderate) or 1 (Low).
nge to the equipment or process.




stic scenarios. Listed below are examples of factors that may be considered in determining the likelihood.


ed number of trained personnel, etc)
PROCESS


EPTABLE



NAL RISK CONTROL



ONTROL REQUIRED

				
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posted:8/8/2011
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