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Center for Biotechnology Education 6th Annual Research Symposium


									                             The Johns Hopkins University

Center for Biotechnology Education
  6th Annual Research Symposium
An evening of networking, poster presentations, and speakers

                                           > May 11, 2011
                                             6– 8:00 pm

                            Montgomery County Campus
                              Building 3 & Gilchrist Hall

    About the Center for Biotechnology Education
    Preparing the leaders of today, tomorrow and the next generation.

    The Center for Biotechnology Education was created to expand the scope
    of biotechnology education to build a pipeline of students and professionals
    prepared to achieve success in K-12 education, graduate school, and the
    work environment in the fields of biotechnology, bioinformatics, bioscience
    regulatory affairs, and bioscience business and leadership.

    The 6th Annual Research Symposium is an opportunity for the Center to
    showcase its strengths in the area of biotechnology education and research.

6:00pm  Building 3, Room 121
Student research poster presentations and networking reception
Light refreshments will be served

Posters from NCI, USAMRIID, and Noblis Fellows, Independent Research
Projects, theses and MCPS students

7:00pm   Gilchrist Hall, Auditorium
Welcoming remarks

Dr. Judith Babbitts
Vice Dean, Advanced Academic Programs

Speaker Introduction

Dr. Richard McCarty
Chair, Center for Biotechnology Education

Keynote Address

Dr. Yves Pommier
Chief, Laboratory of Molecular Pharmacology,
Center for Cancer Research, NCI

    About the Speakers

                         KEYNOTE SPEAKER

                         Yves Pommier, MD, PhD
                         Chief, Laboratory of Molecular Pharmacology,
                         Center for Cancer Research, NCI

                          Dr. Pommier received his MD and PhD degrees from the
    University of Paris, France and has been at the NIH since 1981. Dr. Pommier is
    a member of the Molecular Target steering committee at the NCI. He received
    an NIH Merit Award for his role in elucidating the function of topoisomerase
    enzymes as targets for anticancer drugs and Federal Technology Transfer
    Awards for studies on HIV-1 integrase and DNA topoisomerase inhibitors.
    Dr. Pommier is a program committee member of the American Association
    for Cancer Research, Senior Editor for Cancer Research, and associate editor
    for Cancer Research, Molecular Pharmacology, Leukemia, The Journal of
    Experimental Therapeutics and Oncology, The International Journal of
    Oncology, and Drug Resistance Updates. Dr. Pommier holds several patents
    for inhibitors of DNA topoisomerases I and II and HIV-1 integrase inhibitors.

                     Judith Babbitts, PhD
                     Vice Dean, Advanced Academic Programs
                     Krieger School of Arts and Sciences

                     Dr. Babbitts has been in her current role as Vice Dean
                     since the fall of 2010. Prior to joining Hopkins she
                     worked for the International Honors Program (IHP) in
Boston, a comparative international education program founded in 1958, as
the International School of America. She served as academic dean at IHP and
before that was director of the Hubert H. Humphrey Fellowship Program,
a US State Department-funded program administered by the Institute of
International Education. In addition to her administrative experience,
Dr. Babbitts has taught undergraduate and graduate students both in the
US and abroad. She holds an MA and a PhD from Yale University in American
Studies, an MA in Women’s History from Sarah Lawrence College, and a
BA in English from Rutgers University. As a Fulbright lecturer, she taught
American History and American Studies in Tokyo, Japan.

                     Richard McCarty, PhD
                     Center for Biotechnology Education, Chair

                      Dr. McCarty is the William D. Gill Professor of Biology,
                      Emeritus and is Dean Emeritus of the Zanvyl Krieger
                      School of Arts and Sciences. Dr. McCarty received his
PhD in Biochemistry from Johns Hopkins University. For nearly 25 years he
was on the faculty of the Section of Biochemistry, Molecular and Cell Biology
at Cornell University. Dr. McCarty was Chair of the Section for five years and
was Director of Cornell’s Biotechnology Program for three years. In 1990,
he returned to Johns Hopkins as Chair of the Department of Biology and has
served as the Interim Dean of the Krieger School and as the James B. Knapp
Dean of the Krieger School.

    Poster Presentations
    Participants in the poster session include:
    »»National Cancer Institute (NCI) fellows in the Molecular Targets and
      Drug Discovery Technologies concentration of the Master of Science
      in Biotechnology degree

    »»United States Army Medical Research Institute of Infectious Diseases
      (USAMRIID) fellows in the Biodefense concentration of the Master of
      Science in Biotechnology degree

    »»A Noblis, Inc. fellow in the Master of Science in Bioinformatics degree
    »»Students who have completed research projects in bioscience and
      bioinformatics as part of their degree requirements for the Master of
      Science in Biotechnology, Bioinformatics, and Bioscience Regulatory
      Affairs degrees

    »»High school students from the Montgomery County Public School
      System (MCPS) presenting their research posters from their internships

    The following is the full list of participants, along with their poster topics:

    Waleed Haso¹, Ira Pastan², Richard Morgan³, Crystal Mackall¹, and Rimas Orentas¹
    Anti-CD22 Chimeric Antigen Receptors for Immunotherapy of B Lineage
    Leukemia and Lymphoma. 1. Pediatric Oncology Branch, NCI, CCR, 2.
    Laboratory of Molecular Biology, NCI, CCR, 3. Surgery Branch, NCI, CCR.

    Derek Kong, Aaron Schetter, and Curtis Harris
    Association of miR-135b and Adenomatous Polyposis Coli Gene Expression
    in Human Colon Cancer, Crohn’s Disease, and Inflammatory Bowel Disease.
    National Cancer Institute.

    Christopher Larrimore and Brad St. Croix
    Evaluation of CD276 as a Novel Angiogenic Anti-Tumor Target. National
    Cancer Institute–Frederick, Tumor Angiogenesis Section of the Mouse
    Cancer Genetic Program and Johns Hopkins University.

Lara R. Mittereder, Christine C. Tomlinson, Christina N. Bennett, and Jeffrey E. Green
Identification of Novel Targeted Therapies for Human Basal-type Breast
Cancer. Laboratory of Cancer Biology and Genetics, Center for Cancer
Research, National Cancer institute, NIH.

Barbara Saber, Chunyu Zhang, Joell Gills, Willie Wilson, and Phillip A. Dennis
Application of a Novel Cell-based Dual Luciferase Assay to Identify Inducers
of the Tumor Suppressor RhoB. Medical Oncology Branch, Center for Cancer
Research, NCI.

Bethany Biron, David Dyer and Louise M. Pitt
Indication Markers for the Treatment of Pneumonic Plague in African Green
Monkeys. Center for Aerobiological Sciences, USAMRIID.

Nathan D. Grubaugh¹², Lawrence Petz², Sarah Pisarcik², Vanessa Melanson²,
Monica O’Guinn², Lewis Long², and John S. Lee²
Development of a Portable DNA Microarray for the Simultaneous Detection of
Arbovirus, Blood-meal, and Arthropod Species in the Field. 1. Johns Hopkins
University, Advanced Biotechnology Studies, 2. USAMRIID, Surveillance

Kaatz, L.K., Jenkins, A. L., Cote, C. K., and Welkos, S.L.
Characterization of Multiple Genes of the MarR-like Family and their Role
in Bacillus anthracis Pathogenesis. Bacteriology Division, USAMRIID.

Miriam A. Khan¹², Ashley E. Keeney¹, Lisa E. Hensley¹, Jonathan E. Nuss¹, and
Darci R. Smith¹
Identification of Host Factors in Rift Valley Fever Virus Infection through
Mass Spectroscopy. 1. USAMRIID, 2. Johns Hopkins University.

Anna Kincaid, Ricky L. Ulrich, and Rekha G Panchal
Antibiotic Potentiators Targeting SOS Induction, SOS response in Burkholderia
thailandensis DW503. USAMRIID.

Tiara Moore, David O’Brien, and Michelle Canby
Examination of the Relationship of Humoral Immune Response to Skin-
test Antigen Reactions in Rabbits Vaccinated with the IND Q Fever Vaccine.

    Hemanshi Chawla, Jason Berk, and Katherine L Wilson
    Mitotic Regulation of Nuclear Membrane Protein Emerin. Department
    of Cell Biology, Johns Hopkins University, School of Medicine.

    Kanika Chawla, Natini Jinawath, Raluca Yonescu, and Constance Griffin
    Genetic Variation in miRNA Associated with Fanconi Anemia Pathway
    Genes Implicated in Familial Pancreatic Cancer. Molecular Pathology Lab,
    Department of Pathology, The Johns Hopkins Hospital.

    M. Gadiya, B. Krishnamachary, N. Mori, Y. Mironchik, S. Kakkad, K. Glunde, and
    Z.M. Bhujwalla
    Effect of Choline Kinase and Phospholipase D1 Downregulation in Breast
    Cancer Cells using Interfering RNA. Johns Hopkins University In Vivo Cellular
    Molecular Imaging Center Program, The Russell H. Morgan Department of
    Radiology and Radiological Science, The Johns Hopkins University School
    of Medicine

    Olukemi Abolude and Kevin Galens
    An Evaluation of Non-coding RNA Prediction Tools. Institute for Genome
    Sciences, University of Maryland School of Medicine.

    Matthew Lera¹²³and Oana Marcu1¹4
    Contrasting Oxidative Stress Response Mechanisms in Novel Strains of
    Bacillus Isolated from the Mars-analog, Mojave Desert. 1. NASA Ames
    Research Center, 2. Johns Hopkins University, 3. Lockheed Martin Space
    Operations, 4. SETI Institute.

    Malcolm Matalka and Samuel V Angiuoli
    Para-Mugsy: Parallel Multiple Alignment of Whole Genomes. Johns Hopkins
    University and the Institute for Genome Sciences.

    Julie Ann Costantino, Darran Wigelsworth, Loreen Lofts, St. Patrick Reid, Krishna
    Kota, Dutch Boltz, Brian Peyser, and Sina Bavari
    The Role of Kinases During Alphavirus Infection. USAMRIID.

    Rudy Park and Russell Hill
    Using nifH Gene to Detect Nitrogen Fixing Endosymbionts in Microalgae.
    Johns Hopkins University, Advanced Biotechnology Studies and University
    of Maryland Center for Environmental Science.

Rajita Vatapalli,1 Daria A. Gaykalova1, Michael Ochs,2 Yingyang Wei,2 Patrick
Hennessey, 1 David Zaboli, 1 Tanbir Khan,1 Zubair Khan, 1 William Westra,3 David
Sidransky,1,3 and Joseph A. Califano1,3,4
Integrative Analysis of Epigenetic and Transcriptional Alterations in Head and
Neck Squamous Cell Carcinomas. 1. Department of Otolaryngology—Head and
Neck Surgery, Johns Hopkins Medical Institutions, 2. Division of Oncology
Biostatistics, Department of Oncology, Johns Hopkins Medical Institutions,
3. Department of Pathology, Johns Hopkins Medical Institutions, 4. Milton J.
Dance Head and Neck Center, Greater Baltimore Medical Center.

Mario Morken, Ray Ahmed, David Auerbach, and Julie Poore.
Denosumab: Forecasting a Blockbuster, The 2011 Kellogg Biotech & Healthcare
Case Competition. MS/MBA in Biotechnology program at the Johns Hopkins

Kami Chiotti and Catherine Campbell.
Data Mining for Modeling Complex Process in Infectious Disease.
Noblis and Johns Hopkins University.

Vishaldeep S. Sarkaria1 and Michael F. Ochs2.
Methylation-adjusted gene set analysis. 1. MS in Biotechnology, Johns
Hopkins University, and 2. The Sidney Kimmel Comprehensive Cancer Center,
Johns Hopkins University.

     Inspiring the next generation
     Montgomery County Public School High School Students
     Participating in the research symposium are high school students, who have
     completed research projects as a part of their internships. The internship
     program gives highly motivated students an opportunity to participate in
     authentic research.

     Jay Feldman Total RNA Yield in Peripheral Blood of Men with Nonmetastatic
     Prostate Cancer Receiving External Beam Radiation Therapy

     Nick Shah      Into the Secrets of Strokes

     Sanchari Ghosh Identifying sequence determinants that regulate protein

     Divya Sahajwalla     Improved Device Fabrication for Microchip Electrophoresis

     Justin Muste Synonymous Mutation Val107Val Impacts Expression and
     Function of Coagulation Factor IX

     Le Qi Expression and functional characterization of black cohosh (actaea
     racemosa) genes in saccharomyces cerevisiae

     Adavit Iyer Generation of Putative Ceramide Phosphoethanolamine Synthase
     mutants in Drosophila – Part 1

     Zachary Siegel Synchronizing employee information

     Olivia Lu   Environmental health safety: hazardous waste

     Matt Jeffers     Biomolecular labeling

     Victor Wang Engineering Novel Antifungal Resistance in Arabidopsis
     at the Host Pathogen Interface

     Earl Lee Investigating the role of phosphoinositides in basal and
     RPW8-mediated immunity against powdery mildew

     About the Certificate in Biotechnology Education
     This 20 credit graduate certificate is a joint offering from the School
     of Education and the Krieger School of Arts and Sciences Center for
     Biotechnology Education, which leverages the university’s expertise in
     bioscience and teacher preparation. The certificate is designed to allow grade
     7-12 school science teachers, as well as curriculum and instructional leaders,
     to strengthen their own content knowledge and pedagogic techniques in
     bioscience and develop ways to teach bioscience effectively in their classrooms.

Our degrees

Our graduate programs are designed for working professionals — delivering
the rigorous and practical curriculum they need to advance their careers
or academic ambitions. Johns Hopkins’ Advanced Biotechnology Studies
Program is rooted in the multidisciplinary skills of basic research, drug
discovery technologies, bioinformatics, regulatory affairs, and product
commercialization that the industry demands. The program offers four
master’s degrees, fellowships, and certificates.

Graduate Degree Programs
»»Master of Science in Biotechnology *
»»Master of Science in Bioinformatics *
  (offered jointly with the Whiting School of Engineering)

»»Master of Science in Bioscience Regulatory Affairs *
»»Master of Science in Biotechnology / Master of Business Administration
  (offered jointly with the Carey Business School)

* Degrees available fully online

The Johns Hopkins University ABS Program has partnered with three leaders
in the industry to offer master’s fellowships that prepare the next generation
of scientists and professionals in the emerging fields of drug discovery,
biodefense, and bioinformatics.

»»National Cancer Institute Molecular Targets and Drug Discovery

»»United States Army Medical and Research Institute of Infectious Diseases
  Biodefense Fellowship

»»Noblis Bioinformatics Independent Research Project Fellowship

»» Certificate in Biotechnology Enterprise
»»Certificate in Biotechnology Education
  (offered jointly with the School of Education)

Montgomery County Campus
9601 Medical Center Drive
Rockville, MD 20850

Homewood Campus
Wyman Park Building, S740
Baltimore, MD 21218

Contact Information




                              Center for
                              Biotechnology Education

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