Travel Vaccines Market to 2017 - Growth in International Travel and Higher Incidences of Infectious Diseases in Emerging Economies to Drive the Market by GBIResearch

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									         Travel Vaccines Market to 2017 - Growth in International
           Travel and Higher Incidences of Infectious Diseases in
                  Emerging Economies to Drive the Market
     Reference Code: GBIHC093MR                                                                                 Publication Date: April 2011

                                       The global travel vaccines market is one of the most lucrative markets in the pharmaceutical
                                       industry. It is expected to witness growth during the forecast period because of the increase in
                                       outbound travel and increase in vaccination coverage due to increase in awareness about vaccine-
                                       preventable diseases. The travel vaccine size is calculated by adding together the global revenues
                                       for the different indications (hepatitis A, hepatitis B, rabies, typhoid fever, yellow fever, Japanese
                                       encephalitis and meningococcal meningitis). The growth is attributable to the launch of new
                                       vaccines in the Japanese encephalitis and meningococcal meningitis therapeutics market. The
                                       robust growth of the travel vaccines market is also attributable to increasing antimicrobial
                                       resistance to antibiotics.
                                       The Global Travel Vaccine Market is forecast to Show Growth
   The global travel vaccines
   market is estimated to              In 2010, the global travel vaccines market was estimated to be worth $2.7 billion, representing a
   reach $6.6 billion,                 Compound Annual Growth Rate (CAGR) of 11% between 2002 and 2010. By 2017, the global
   indicating a CAGR of 13%            travel vaccines market is estimated to reach $6.6 billion, indicating a CAGR of 13% between 2010
   between 2010 and 2017               and 2017. The growth of the travel vaccines market is attributable to an increase in outbound travel
                                       and increase in vaccination coverage due to increasing antimicrobial resistance and awareness
                                       about vaccine-preventable diseases such as hepatitis A, hepatitis B, rabies, typhoid fever, yellow
                                       fever, Japanese encephalitis and meningococcal meningitis.
                                       The target population base of the travel vaccines market includes outbound travelers. The vaccines
                                       used in the travel vaccines market for the prevention of hepatitis A, hepatitis B, rabies, typhoid
                                       fever, yellow fever, Japanese encephalitis and meningococcal meningitis are manufactured by
                                       Sanofi Pasteur, Merck, Novartis, GlaxoSmithKline (GSK) and Intercell. Sanofi Pasteur and GSK are
                                       the leading players in the travel vaccines market. They generate 85% of the total travel vaccine
                                       revenues. Sanofi Pasteur manufactures vaccines for yellow fever, Japanese encephalitis, typhoid
                                       fever, rabies, and meningococcal meningitis therapeutics markets. GSK manufactures vaccines for
                                       hepatitis A and hepatitis B therapeutics markets.
                                       The global travel vaccines market is expected to increase at a CAGR of 13% in the forecast period,
                                       from 2010 to 2017 because of the increase in outbound travel and increase in vaccination coverage
                                       due to increasing antimicrobial resistance and awareness about vaccine-preventable diseases.




Travel Vaccines Market to 2017 - Growth in International Travel                                              GBIHC093MR /Published APR 2011
and Higher Incidences of Infectious Diseases in Emerging
Economies to Drive the Market                                                                                                            Page 1
                                                                          © GBI Research. This is a licensed product and is not to be photocopied
                                        Travel Vaccines Therapeutics Market, Global, Revenue Forecasts ($m), 2002-2017

                                                                  7,000


                                                                                                     CAGR (2010-2017) - 13%
                                                                  6,000



                                                                  5,000




                                                  Revenues ($m)
                                                                  4,000
                                                                          CAGR (2002-2010) - 11%


                                                                  3,000



                                                                  2,000



                                                                  1,000



                                                                     0
                                                                                 2002                       2010                       2017


                                        Source: GBI Research, CDC, United Nations World Tourism Organization (UNWTO)



                                       Growth in International Travel and Higher Incidences of Infectious Diseases in Emerging
                                       Economies to Drive the Market
                                       The increase in outbound travel and increase in awareness about vaccine-preventable infectious
                                       diseases will drive the market. The travel vaccine therapeutics market is estimated to grow from
                                       $2.7 billion in 2010 to $6.6 billion in 2017, at a CAGR of 13%. The growth is attributable to the
                                       increase in outbound travelers to Asia, South America and Africa. The international travelers to
                                       Asia and South America will increase because of improvement in infrastructure and growth
                                       potential for companies to expand their businesses.
                                       The travel vaccines market will grow due to higher incidence of infectious diseases like hepatitis A,
                                       hepatitis B, rabies, typhoid fever, yellow fever, Japanese encephalitis and meningococcal
                                       meningitis in the emerging economies, which will drive the market. This can be elucidated by the
                                       geographic distribution of the diseases. The majority of the indications are prevalent in emerging
                                       economies like India, China, Brazil and Argentina. The other reason for the growth of the travel
                                       vaccines market can be attributed to the fact that the rate of improvement in health conditions is not
                                       equal to the rate of development in the emerging economies.
                                       Emergence of New Vaccines and Increasing Antimicrobial Resistance to Drive the Market
                                       The launch of new vaccines like Menveo and Ixiaro for meningococcal meningitis and Japanese
                                       encephalitis will help in the growth of these therapeutics markets. Menveo, which was licensed for
                                       use in 2010, will help in increasing revenues. The vaccine is also awaiting approval for use in
                                       infants, as meningitis is fatal in children. Ixiaro, which was licensed for use in 2009, is
                                       manufactured by Intercell and is expected to drive the Japanese encephalitis therapeutics market.
                                       The travel vaccines market is also expected to grow because many pharmaceutical companies are
                                       looking for novel ways of combating antimicrobial resistance to antibiotics. Increase in the use of
                                       vaccines for vaccine-preventable diseases in the forecast period is expected to drive the travel
                                       vaccines market.




Travel Vaccines Market to 2017 - Growth in International Travel                                                               GBIHC093MR /Published APR 2011
and Higher Incidences of Infectious Diseases in Emerging
Economies to Drive the Market                                                                                                                           Page 2
                                                                                         © GBI Research. This is a licensed product and is not to be photocopied
                                       1 Table of Contents
                                       1   Table of Contents ........................................................................................................................ 3
                                           1.1    List of Tables..................................................................................................................... 5
                                           1.2    List of Figures ................................................................................................................... 8
                                       2   Global Travel Vaccines Market to 2017– Introduction ............................................................... 10
                                           2.1    GBI Research Report Guidance ..................................................................................... 11
                                       3   Global Travel Vaccines Market to 2017 – Market Overview ...................................................... 12
                                           3.1    Introduction ..................................................................................................................... 12
                                           3.2    Revenue Forecasts for the Travel Vaccines Market ....................................................... 12
                                           3.3    Drivers and Barriers for the Travel Vaccines Market....................................................... 13
                                              3.3.1    Drivers for the Travel Vaccines Market.................................................................... 13
                                              3.3.2    Barriers for the Travel Vaccines Market .................................................................. 14
                                       4   Global Travel Vaccines Market to 2017 – Geographical Landscape ......................................... 15
                                           4.1    Revenue Analysis by Geography .................................................................................... 15
                                              4.1.1    The US .................................................................................................................... 17
                                              4.1.2    Top Five Countries of Europe .................................................................................. 20
                                              4.1.3    Japan ....................................................................................................................... 23
                                              4.1.4    Rest of the World ..................................................................................................... 26
                                       5   Global Travel Vaccines Market to 2017 – Therapeutic Landscape............................................ 29
                                           5.1    Hepatitis A....................................................................................................................... 29
                                              5.1.1    Introduction .............................................................................................................. 29
                                              5.1.2    Revenue .................................................................................................................. 30
                                              5.1.3    Cost of Vaccination.................................................................................................. 31
                                              5.1.4    Vaccination Coverage ............................................................................................. 32
                                              5.1.5    Drivers and Barriers for the Hepatitis A Market ....................................................... 33
                                           5.2    Hepatitis B....................................................................................................................... 34
                                              5.2.1    Introduction .............................................................................................................. 34
                                              5.2.2    Revenue .................................................................................................................. 35
                                              5.2.3    Cost of Vaccination.................................................................................................. 36
                                              5.2.4    Vaccination Coverage ............................................................................................. 37
                                              5.2.5    Drivers and Barriers for the Hepatitis B Market ....................................................... 38
                                           5.3    Rabies ............................................................................................................................. 39
                                              5.3.1    Introduction .............................................................................................................. 39
                                              5.3.2    Revenue .................................................................................................................. 40
                                              5.3.3    Cost of Vaccination.................................................................................................. 41
                                              5.3.4    Vaccination Coverage ............................................................................................. 42
                                              5.3.5    Drivers and Barriers for the Rabies Market ............................................................. 43
                                           5.4    Typhoid Fever ................................................................................................................. 44
                                              5.4.1    Introduction .............................................................................................................. 44
                                              5.4.2    Revenue .................................................................................................................. 45
                                              5.4.3    Cost of Vaccination.................................................................................................. 46
                                              5.4.4    Vaccination Coverage ............................................................................................. 47
                                              5.4.5    Drivers and Barriers for the Typhoid Fever Market .................................................. 48
                                           5.5    Yellow Fever ................................................................................................................... 49
                                              5.5.1    Introduction .............................................................................................................. 49
                                              5.5.2    Revenue .................................................................................................................. 50
                                              5.5.3    Cost of Vaccination.................................................................................................. 51
                                              5.5.4    Vaccination Coverage ............................................................................................. 52
                                              5.5.5    Drivers and Barriers for the Yellow Fever Market .................................................... 53
                                           5.6    Japanese Encephalitis .................................................................................................... 54
                                              5.6.1    Introduction .............................................................................................................. 54
                                              5.6.2    Revenue .................................................................................................................. 55
                                              5.6.3    Cost of Vaccination.................................................................................................. 56
                                              5.6.4    Vaccination Coverage ............................................................................................. 57


Travel Vaccines Market to 2017 - Growth in International Travel                                                                         GBIHC093MR /Published APR 2011
and Higher Incidences of Infectious Diseases in Emerging
Economies to Drive the Market                                                                                                                                                  Page 3
                                                                                         © GBI Research. This is a licensed product and is not to be photocopied
                                              5.6.5    Drivers and Barriers for the Japanese Encephalitis Market ..................................... 58
                                           5.7    Meningococcal Meningitis ............................................................................................... 59
                                              5.7.1    Introduction .............................................................................................................. 59
                                              5.7.2    Revenue .................................................................................................................. 60
                                              5.7.3    Cost of Vaccination.................................................................................................. 61
                                              5.7.4    Vaccination Coverage ............................................................................................. 62
                                              5.7.5    Drivers and Barriers for the Meningococcal Meningitis Market ................................ 63
                                           5.8    Enterotoxigenic Escherichia Coli (Traveler’s Diarrhea) ................................................... 64
                                              5.8.1    Introduction .............................................................................................................. 64
                                              5.8.2    Drivers and Barriers for the Enterotoxigenic Escherichia Coli Market ..................... 65
                                       6   Travel Vaccines Market – Product Pipeline Analysis ................................................................. 66
                                           6.1    Introduction ..................................................................................................................... 66
                                              6.1.1    Research and Development Pipeline – Hepatitis A Vaccines .................................. 68
                                              6.1.2    Research and Development Pipeline – Hepatitis B Vaccines .................................. 69
                                              6.1.3    Research and Development Pipeline – Rabies Vaccines ........................................ 74
                                              6.1.4    Research and Development Pipeline – Typhoid Fever Vaccines ............................ 76
                                              6.1.5    Research and Development Pipeline – Yellow Fever Vaccines .............................. 78
                                              6.1.6    Research and Development Pipeline – Japanese Encephalitis Vaccines ............... 79
                                              6.1.7    Research and Development Pipeline – Enterotoxigenic Escherichia Coli Vaccines 80
                                              6.1.8    Research and Development Pipeline – Meningococcal Meningitis Vaccines .......... 81
                                       7   Travel Vaccines Market – Competitive Landscape .................................................................... 84
                                           7.1    Market Share Analysis: Travel Vaccines Market ............................................................. 84
                                           7.2    Competitive Profiling ....................................................................................................... 85
                                              7.2.1    Sanofi Pasteur ......................................................................................................... 85
                                              7.2.2    GlaxoSmithKline plc ................................................................................................ 87
                                              7.2.3    Merck & Co., Inc ...................................................................................................... 88
                                              7.2.4    Novartis AG ............................................................................................................. 90
                                              7.2.5    Intercell AG .............................................................................................................. 91
                                       8   Travel Vaccines Market – M&A Landscape ............................................................................... 92
                                           8.1    M&A Landscape.............................................................................................................. 92
                                              8.1.1    M&A Deals by Year ................................................................................................. 92
                                              8.1.2    M&A Deals by Geography ....................................................................................... 93
                                              8.1.3    M&A Deals by Value................................................................................................ 94
                                              8.1.4    Major M&A Deals by Value ...................................................................................... 95
                                              8.1.5    M&A Deals by Deal Type ........................................................................................ 96
                                              8.1.6    M&A Deals by Deal Sub-Type ................................................................................. 97
                                           8.2    R&D Licensing Agreements ............................................................................................ 98
                                              8.2.1    Deals by Year .......................................................................................................... 98
                                              8.2.2    Deals by Geography ................................................................................................ 99
                                              8.2.3    Deals by Value ($) ................................................................................................. 100
                                           8.3    Co-Developments ......................................................................................................... 101
                                              8.3.1    Co-Developments by Year .................................................................................... 101
                                              8.3.2    Co-developments by Geography ........................................................................... 102
                                       9   Travel Vaccines Market – Appendix ........................................................................................ 103
                                           9.1    Market Definitions ......................................................................................................... 103
                                           9.2    Abbreviations ................................................................................................................ 103
                                           9.3    Research Methodology ................................................................................................. 103
                                              9.3.1    Coverage ............................................................................................................... 103
                                              9.3.2    Secondary Research ............................................................................................. 104
                                              9.3.3    Primary Research .................................................................................................. 104
                                              9.3.4    Expert Panel Validation ......................................................................................... 104
                                           9.4    Contact Us .................................................................................................................... 105
                                           9.5    Disclaimer ..................................................................................................................... 105
                                           9.6    Sources ......................................................................................................................... 105



Travel Vaccines Market to 2017 - Growth in International Travel                                                                        GBIHC093MR /Published APR 2011
and Higher Incidences of Infectious Diseases in Emerging
Economies to Drive the Market                                                                                                                                                Page 4
                                                                                         © GBI Research. This is a licensed product and is not to be photocopied
                                       1.1     List of Tables
                                       Table 1:    Travel Vaccines Therapeutics Market, Global, Revenue ($m), 2002-2010 .................... 12
                                       Table 2:    Travel Vaccines Therapeutics Market, Global, Revenue Forecasts ($m), 2010-2017 .. 12
                                       Table 3:    Travel Vaccines Therapeutics Market, Global, Revenue Analysis by Geography ($m),
                                                   2002-2010 ...................................................................................................................... 15
                                       Table 4:    Travel Vaccines Therapeutics Market, Global, Revenue Analysis by Geography ($m),
                                                   2010-2017 ...................................................................................................................... 16
                                       Table 5:    Travel Vaccines Therapeutics Market, the US, Revenue ($m), 2002-2010 ................... 17
                                       Table 6:    Travel Vaccines Therapeutics Market, the US, Revenue Forecasts ($m), 2010-2017 .. 17
                                       Table 7:    Travel Vaccines Therapeutics Market, the US, Cost of Vaccination ($), 2002-2010 ..... 18
                                       Table 8:    Travel Vaccines Therapeutics Market, the US, Cost of Vaccination ($), 2010-2017 ..... 18
                                       Table 9:    Travel Vaccines Therapeutics Market, the US, Vaccinated Travelers (million), 2002-2010
                                                   ....................................................................................................................................... 19
                                       Table 10:   Travel Vaccines Therapeutics Market, the US, Vaccinated Travelers Forecasts (million),
                                                   2010-2017 ...................................................................................................................... 19
                                       Table 11:   Travel Vaccines Therapeutics Market, Top Five Countries of Europe, Revenue ($m),
                                                   2002- 2010 ..................................................................................................................... 20
                                       Table 12:   Travel Vaccines Therapeutics Market, Top Five Countries of Europe, Revenue
                                                   Forecasts ($m), 2010- 2017 .......................................................................................... 20
                                       Table 13:   Travel Vaccines Therapeutics Market, Top Five Countries of Europe, Cost of
                                                   Vaccination ($), 2002-2010 ............................................................................................ 21
                                       Table 14:   Travel Vaccines Therapeutics Market, Top Five Countries of Europe, Cost of
                                                   Vaccination ($), 2010-2017 ............................................................................................ 21
                                       Table 15:   Travel Vaccines Therapeutics Market, Top Five Countries of Europe, Vaccinated
                                                   Travelers (million), 2002-2010........................................................................................ 22
                                       Table 16:   Travel Vaccines Therapeutics Market, Top Five Countries of Europe, Vaccinated
                                                   Travelers Forecasts (million), 2010-2017 ....................................................................... 22
                                       Table 17:   Travel Vaccines Therapeutics Market, Japan, Revenue ($m), 2002- 2010.................... 23
                                       Table 18:   Travel Vaccines Therapeutics Market, Japan, Revenue Forecasts ($m), 2010-2017 ... 23
                                       Table 19:   Travel Vaccines Therapeutics Market, Japan, Cost of Vaccination ($), 2002-2010 ....... 24
                                       Table 20:   Travel Vaccines Therapeutics Market, Japan, Cost of Vaccination ($), 2010-2017 ....... 24
                                       Table 21:   Travel Vaccines Therapeutics Market, Japan, Vaccinated Travelers (million), 2002-2010
                                                   ....................................................................................................................................... 25
                                       Table 22:   Travel Vaccines Therapeutics Market, Japan, Vaccinated Travelers Forecasts (million),
                                                   2010-2017 ...................................................................................................................... 25
                                       Table 23:   Travel Vaccines Therapeutics Market, Rest of the World, Revenue ($m), 2002-2010 .. 26
                                       Table 24:   Travel Vaccines Therapeutics Market, Rest of the World, Revenue Forecasts ($m),
                                                   2010-2017 ...................................................................................................................... 26
                                       Table 25:   Travel Vaccines Therapeutics Market, Rest of the World, Cost of Vaccination ($), 2002-
                                                   2010 ............................................................................................................................... 27
                                       Table 26:   Travel Vaccines Therapeutics Market, Rest of the World, Cost of Vaccination ($), 2010-
                                                   2017 ............................................................................................................................... 27
                                       Table 27:   Travel Vaccines Therapeutics Market, Rest of the World, Vaccinated Travelers (million),
                                                   2002-2010 ...................................................................................................................... 28
                                       Table 28:   Travel Vaccines Therapeutics Market, Rest of the World, Vaccinated Travelers
                                                   Forecasts (million), 2010-2017 ....................................................................................... 28
                                       Table 29:   Hepatitis A Therapeutics Market, Global, Revenue ($m), 2002-2010 ............................ 30
                                       Table 30:   Hepatitis A Therapeutics Market, Global, Revenue Forecasts ($m), 2010-2017 ........... 30
                                       Table 31:   Hepatitis A Therapeutics Market, Global, Cost of Vaccination ($), 2002-2010............... 31
                                       Table 32:   Hepatitis A Therapeutics Market, Global, Cost of Vaccination ($), 2010-2017............... 31
                                       Table 33:   Hepatitis A Therapeutics Market, Global, Vaccinated Travelers (million), 2002-2010 ... 32
                                       Table 34:   Hepatitis A Therapeutics Market, Global, Vaccinated Travelers Forecasts (million), 2010-
                                                   2017 ............................................................................................................................... 32
                                       Table 35:   Hepatitis B Therapeutics Market, Global, Revenue ($m), 2002-2010 ............................ 35
                                       Table 36:   Hepatitis B Therapeutics Market, Global, Revenue Forecasts ($m), 2010-2017 ........... 35
                                       Table 37:   Hepatitis B Therapeutics Market, Global, Cost of Vaccination ($), 2002-2010............... 36
                                       Table 38:   Hepatitis B Therapeutics Market, Global, Cost of Vaccination ($), 2010-2017............... 36
                                       Table 39:   Hepatitis B Therapeutics Market, Global, Vaccinated Travelers (million), 2002-2010 ... 37
                                       Table 40:   Hepatitis B Therapeutics Market, Global, Vaccinated Travelers Forecasts (million), 2010-
                                                   2017 ............................................................................................................................... 37
                                       Table 41:   Rabies Therapeutics Market, Global, Revenue ($m), 2002-2010 .................................. 40
                                       Table 42:   Rabies Therapeutics Market, Global, Revenue Forecasts ($m), 2010-2017.................. 40

Travel Vaccines Market to 2017 - Growth in International Travel                                                                          GBIHC093MR /Published APR 2011
and Higher Incidences of Infectious Diseases in Emerging
Economies to Drive the Market                                                                                                                                                     Page 5
                                                                                        © GBI Research. This is a licensed product and is not to be photocopied
                                       Table 43:   Rabies Therapeutics Market, Global, Cost of Vaccination ($), 2002-2010 ..................... 41
                                       Table 44:   Rabies Therapeutics Market, Global, Cost of Vaccination ($), 2010-2017 ..................... 41
                                       Table 45:   Rabies Therapeutics Market, Global, Vaccinated Travelers (million), 2002-2010 .......... 42
                                       Table 46:   Rabies Therapeutics Market, Global, Vaccinated Travelers Forecasts (million), 2010-
                                                   2017 ............................................................................................................................... 42
                                       Table 47:   Typhoid Fever Therapeutics Market, Global, Revenue ($m), 2002-2010....................... 45
                                       Table 48:   Typhoid Fever Therapeutics Market, Global, Revenue Forecasts ($m), 2010-2017 ...... 45
                                       Table 49:   Typhoid Fever Therapeutics Market, Global, Cost of Vaccination ($), 2002-2010 ......... 46
                                       Table 50:   Typhoid Fever Therapeutics Market, Global, Cost of Vaccination ($), 2010-2017 ......... 46
                                       Table 51:   Typhoid Fever Therapeutics Market, Global, Vaccinated Travelers (million), 2002-2010
                                                   ....................................................................................................................................... 47
                                       Table 52:   Typhoid Fever Therapeutics Market, Global, Vaccinated Travelers Forecasts (million),
                                                   2010-2017 ...................................................................................................................... 47
                                       Table 53:   Yellow Fever Therapeutics Market, Global, Revenue ($m), 2002-2010 ......................... 50
                                       Table 54:   Yellow Fever Therapeutics Market, Global, Revenue Forecasts ($m), 2010-2017 ........ 50
                                       Table 55:   Yellow Fever Therapeutics Market, Global, Cost of Vaccination ($), 2002-2010 ........... 51
                                       Table 56:   Yellow Fever Therapeutics Market, Global, Cost of Vaccination ($), 2010-2017 ........... 51
                                       Table 57:   Yellow Fever Therapeutics Market, Global, Vaccinated Travelers (million), 2002-2010 52
                                       Table 58:   Yellow Fever Therapeutics Market, Global, Vaccinated Travelers Forecasts (million),
                                                   2010-2017 ...................................................................................................................... 52
                                       Table 59:   Japanese Encephalitis Therapeutics Market, Global, Revenue ($m), 2002-2010.......... 55
                                       Table 60:   Japanese Encephalitis Therapeutics Market, Global, Revenue For
								
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