“In the News” July 4 - July 18, 2008 Drug- and Pharmacy-related News Brought to You by the Pharmacy Library People Kelowna, BC ALLERGIES Ben-Shoshan M, Kagan R, Primeau MN. Availability of the epinephrine autoinjector at school in children with peanut allergy. Ann Allergy Asthma Immunol. 2008 Jun;100(6):570-5. CARDIOLOGY Coons JC, Battistone S. 2007 guideline update for unstable angina/non-ST-segment elevation myocardial infarction: Focus on antiplatelet and anticoagulant therapies. Ann Pharmacother. 2008 Jun 24. [Epub ahead of print]. Neergaard L. Doctors hopeful easier blood thinners are nearing. YAHOO! ® NEWS. July 14, 2008. Hennekens CH. Fixed-dose combination therapy with statins: Strengths, limitations, and clinical and regulatory considerations. Am J Cardiovasc Drugs. 2008;8(3):155-60. Wilson PW, Bozeman SR, Burton TM et al. Prediction of first events of coronary heart disease and stroke with consideration of adiposity. Circulation. 2008 Jul 8;118(2):124- 30. Stagnitti M. Trends in statins utilization and expenditures for the U.S. civilian noninstitutionalized population, 2000 and 2005. Statistical Brief #205 - Medical Expenditure Panel Survey (MEPS). Rockville MD: Agency for Healthcare Research and Quality (AHRQ); May 2008. Kumanyika SK, Obarzanek E, Stettler N et al. Population-based prevention of obesity. The need for comprehensive promotion of healthful eating, physical activity, and energy balance. A scientific statement from American Heart Association Council on Epidemiology and Prevention, Interdisciplinary Committee for Prevention (formerly the Expert Panel on Population and Prevention Science). Circulation. 2008 Jun 30. [Epub ahead of print]. CAS-RELATED TOPICES The following two articles are related: Bassler D, Busse JW, Karanicolas PJ, Guyatt GH. Evidence-based medicine targets the individual patient. Part 1: How clinicians can use study results to determine optimal individual care. ACP J Club. 2008 Jun 17;148(4):2. Bassler D, Busse JW, Karanicolas PJ, Guyatt GH. Evidence-based medicine targets the individual patient. Part 2: Guides and tools for individual decision-making (Editorial). ACP J Club. 2008 Jul-Aug;149(1):2. CNS Stevens DL. Association between selective serotonin-reuptake inhibitors, second- generation antipsychotics, and neuroleptic malignant syndrome. Ann Pharmacother. 2008 Jul 15. [Epub ahead of print]. Mrazek DA, Rush AJ, Biernacka JM et al. SLC6A4 variation and citalopram response. Am J Med Genet B Neuropsychiatr Genet. 2008 Jul 10. [Epub ahead of print]. French JA, Pedley TA. Clinical practice. Initial management of epilepsy. N Engl J Med. 2008 Jul 10;359(2):166-76. Singh-Manoux A, Gimeno D, Kivimaki M et al. Low HDL cholesterol is a risk factor for deficit and decline in memory in midlife. The Whitehall II Study. Arterioscler Thromb Vasc Biol. 2008 Jun 30. [Epub ahead of print]. Peters R, Beckett N, Forette F et al; for the HYVET investigators. Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): A double-blind, placebo controlled trial. Lancet Neurol. 2008 Jul 7. [Epub ahead of print]. Bissada H, Tasca GA, Barber AM, Bradwejn J. Olanzapine in the treatment of low body weight and obsessive thinking in women with anorexia nervosa: A randomized, double- blind, placebo-controlled trial. Am J Psychiatry. 2008 Jun 16. [Epub ahead of print]. Singh-Manoux A, Gimeno D, Kivimaki M, et al. Low HDL cholesterol is a risk factor for deficit and decline in memory in midlife. The Whitehall II Study. Arterioscler Thromb Vasc Biol. 2008 Jun 30. [Epub ahead of print]. Hitchen L. NICE recommendations have had little effect on multiple sclerosis services five years on. BMJ. 2008 Jul 8;337:a734. doi: 10.1136/bmj.a734. O'Brien J. Antipsychotics for people with dementia. BMJ. 2008 Jul 9;337:a602. doi: 10.1136/bmj.a602. Heavey S. U.S. panel rejects strong epilepsy drug warning. Reuters Health. July 11, 2007. de Abajo FJ, García-Rodríguez LA. Risk of upper gastrointestinal tract bleeding associated with selective serotonin reuptake inhibitors and venlafaxine therapy: Interaction with nonsteroidal anti-inflammatory drugs and effect of acid-suppressing agents. Arch Gen Psychiatry. 2008 Jul;65(7):795-803. Stevenson JR, Schroeder JP, Nixon K et al. Abstinence following alcohol drinking produces depression-like behavior and reduced hippocampal neurogenesis in mice. Neuropsychopharmacology. 2008 Jun 18. [Epub ahead of print]. Stagnitti MN. Antidepressants prescribed by medical doctors in office based and outpatient settings by specialty for the U.S. civilian noninstitutionalized population, 2002 and 2005. Statistical brief #206 - Medical Expenditure Panel Survey (MEPS). Rockville MD: Agency for Healthcare Research and Quality (AHRQ); June 2008. The following two articles are related: Young HN, Bell RA, Epstein RM et al. Physicians' shared decision-making behaviors in depression care. Arch Intern Med. 2008 Jul 14;168(13):1404-8. Hanson JL. Shared decision making: Have we missed the obvious? Arch Intern Med. 2008 Jul 14;168(13):1368-70. DIABETES Bazzano LA, Li TY, Joshipura KJ, Hu FB. Intake of fruit, vegetables, and fruit juices and risk of diabetes in women. Diabetes Care. 2008 Jul;31(7):1311-7. Epub 2008 Apr 4. Dale AC, Vatten LJ, Nilsen TI et al. Secular decline in mortality from coronary heart disease in adults with diabetes mellitus: Cohort study. BMJ. 2008 Jul 1;337:a236. doi: 10.1136/bmj.39582.447998.BE. DRUG COMPOUNDING Kupiec TC, Aloumanis V, Ben M et al. Physical and chemical stability of esomeprazole sodium solutions. Ann Pharmacother. 2008 Jul 9. [Epub ahead of print]. DRUG SAFETY Neviaser AS, Lane JM, Lenart BA et al. Low-energy femoral shaft fractures associated with alendronate use. J Orthop Trauma. 2008 May-Jun;22(5):346-50. Parker-Pope T. A list of drugs that increase falling risk. New York Times. July 10, 2008. AVASTIN (bevacizumab) - Advisories, warnings & recalls for the public. Health Canada. July 11, 2008. Ratio-morphine tablets recalled in Canada due to risk of accidental overdose. Health Canada. July 9, 2008. Kuehn BM. FDA turns to electronic "sentinel" to flag prescription drug safety problems. JAMA. 2008 Jul 9;300(2):156-7. The following two FDA reports are related: Information for healthcare professionals: Fluoroquinolone antimicrobial drugs [ciprofloxacin (marketed as Cipro and generic ciprofloxacin), ciprofloxacin extended release (marketed as Cipro XR and Proquin XR), gemifloxacin (marketed as Factive), levofloxacin (marketed as Levaquin), moxifloxacin (marketed as Avelox), norfloxacin (marketed as Noroxin), and ofloxacin (marketed as Floxin and generic ofloxacin)]. FDA Alert. July 8, 2008. News release: FDA requests boxed warnings on fluoroquinolone antimicrobial drugs: Seeks to strengthen warnings concerning increased risk of tendinitis and tendon Rupture. FDA News. July 8, 2008. ENVIRONMENTAL CONCERNS Dales R, Liu L, Wheeler AJ, Gilbert NL. Quality of indoor residential air and health. CMAJ. 2008 Jul 15;179(2):147-52. Watts G. How clean is your water? BMJ. 2008 Jul 2;337:a237. doi: 10.1136/bmj.a237. GASTROINTESTINAL DISORDERS Laine L, Shah A, Bemanian S. Intragastric pH with oral vs intravenous bolus plus infusion proton-pump inhibitor therapy in patients with bleeding ulcers. Gastroenterology. 2008 Jun;134(7):1836-41. Epub 2008 Mar 10. Peyrin-Biroulet L, Desreumaux P, Sandborn WJ, Colombel JF. Crohn's disease: Beyond antagonists of tumour necrosis factor. Lancet. 2008 Jul 5;372(9632):67-81. INFECTIOUS DISEASES Kuhn L, Aldrovandi GM, Sinkala M et al; Zambia Exclusive Breastfeeding Study. Effects of early, abrupt weaning on HIV-free survival of children in Zambia. N Engl J Med. 2008 Jul 10;359(2):130-41. Epub 2008 Jun 4. Kumwenda NI, Hoover DR, Mofenson LM et al. Extended antiretroviral prophylaxis to reduce breast-milk HIV-1 transmission. N Engl J Med. 2008 Jul 10;359(2):119-29. Epub 2008 Jun 4. Gray GE, Saloojee H. Breast-feeding, antiretroviral prophylaxis, and HIV. N Engl J Med. 2008 Jul 10;359(2):189-91. Epub 2008 Jun 4. Brownstein JS, Freifeld CC, Reis BY, Mandl KD. Surveillance sans frontières: Internet- based emerging infectious disease intelligence and the healthmap project. PLoS Med. 2008 Jul 8;5(7):e151. [Epub ahead of print]. MUSCULOSKELETAL DISEASES Yamaza T, Miura Y, Bi Y et al. Pharmacologic stem cell based intervention as a new approach to osteoporosis treatment in rodents. PLoS ONE. 2008 Jul 9;3(7):e2615. Clinician’s guide: Fracture prevention treatments for postmenopausal women with osteoporosis. Rockville MD: AHRQ Effective Health Care; June 2008. OBESITY Hollis JF, Gullion CM, Stevens VJ et al; Weight Loss Maintenance Trial Research Group. Weight loss during the intensive intervention phase of the weight-loss maintenance trial. Am J Prev Med. 2008 Aug;35(2):118-26. Piomelli D. The element of surprise. Nat Med. 2008 Jul;14(7):720-1. Lee JM. Why young adults hold the key to assessing the obesity epidemic in children. Arch Pediatr Adolesc Med. 2008 Jul;162(7):682-7. The following study and editorial are related: Johnson F, Cooke L, Croker H, Wardle J. Changing perceptions of weight in Great Britain: Comparison of two population surveys. BMJ. 2008 Jul 10;337:a494. doi: 10.1136/bmj.a494. Bleich SN. Public perception of overweight. BMJ. 2008 Jul 10;337:a347. doi: 10.1136/bmj.a347. ONCOLOGY Hoskin PJ. Opioids in context: Relieving the pain of cancer. The role of comprehensive cancer management. Palliat Med. 2008 Jun;22(4):303-9. Zeller JL, Lynm C, Glass RM. JAMA patient page. Prostate cancer. JAMA. 2008 Jul 9;300(2):236. Lu-Yao GL, Albertsen PC, Moore DF et al. Survival following primary androgen deprivation therapy among men with localized prostate cancer. JAMA. 2008 Jul 9;300(2):173-81. Zahid M, Gaikwad NW, Ali MF et al. Prevention of estrogen-DNA adduct formation in MCF-10F cells by resveratrol. Free Radic Biol Med. 2008 Jul 15;45(2):136-45. Epub 2008 Apr 8. Kolata G, Pollack A. Costly cancer drug offers hope, but also a dilemma. New York Times. July 6, 2008. Finlay I, Crisp N. Drugs for cancer and copayments. BMJ. 2008 Jun 30;337:a527. doi: 10.1136/bmj.a527. Donaldson C. Top-ups for cancer drugs: Can we kill the zombie for good? BMJ. 2008 Jun 30;337:a578. doi: 10.1136/bmj.a578. The following two articles are Parts I and II of a Clinical Review in BMJ: Turner NC, Jones AL. Management of breast cancer--Part I. BMJ. 2008 Jul 4;337:a421. doi: 10.1136/bmj.a421. Turner NC, Jones AL. Management of breast cancer--Part II. BMJ. 2008 Jul 11;337:a540. doi: 10.1136/bmj.a540. The following two articles are related: Strong V, Waters R, Hibberd C. Management of depression for people with cancer (SMaRT oncology 1): A randomised trial. Lancet. 2008 Jul 5;372(9632):40-8. Rodin G. Treatment of depression in patients with cancer. Lancet. 2008 Jul 5;372(9632):8-10. OTCs, NUTRITION, NHPs, LIFESTYLE, etc. Ranilla LG, Kwon YI, Genovese MI et al. Antidiabetes and antihypertension potential of commonly consumed carbohydrate sweeteners using in vitro models. J Med Food. 2008 Jun;11(2):337-48. Hartman TC, van Rijswijk E. Fungal nail infection. BMJ. 2008 Jul 10;337:a429. doi: 10.1136/bmj.39357.558183.94. Williams DM, Matthews CE, Rutt C et al. Interventions to increase walking behavior. Med Sci Sports Exerc. 2008 Jul;40(7 Suppl):S567-73. Hollis JF, Gullion CM, Stevens VJ et al; Weight Loss Maintenance Trial Research Group. Weight loss during the intensive intervention phase of the weight-loss maintenance trial. Am J Prev Med. 2008 Aug;35(2):118-26. Becker DJ, Gordon RY, Morris PB et al. Simvastatin vs therapeutic lifestyle changes and supplements: Randomized primary prevention trial. Mayo Clin Proc. 2008 Jul;83(7):758-64. Parker-Pope T. Should doctors lecture patients about their weight? New York Times. July 9, 2008. Andrade AM, Greene GW, Melanson KJ. Eating slowly led to decreases in energy intake within meals in healthy women. J Am Diet Assoc. 2008 Jul;108(7):1186-91. O’Connor A. The claim: Beware of drink mixers based on diet soda. New York Times. July 8, 2008. PEDIATRICS Pearce T. Reduced-fat milk OK for all toddlers, doctors say. Globe and Mail. July 15, 2008. Beck L. Food for thought: Cholesterol kids: Rx or exercise. Globe and Mail. July 16, 2008. Parker-Pope T. Ideas & trends: Palpitations over a new pill for kids. New York Times. July 13, 2008. C.S Mott Children’s Hospital National Poll on Children’s Health: Obesity tops list of biggest health problems for kids in 2008. Ann Arbor MI: C.S. Mott Children’s Hospital, University of Michigan Department of Pediatrics and Communicable Diseases, and the University of Michigan Child Health Evaluation and Research (CHEAR) Unit. 2008 Jul 14;4(2):1-2. Hughes V. Extra drugs and slower weaning lowers HIV risk for newborns. Nat Med. 2008 Jul;14(7):698. Cregin R, Rappaport AS, Montagnino G et al. Improving pain management for pediatric patients undergoing nonurgent painful procedures. Am J Health Syst Pharm. 2008 Apr 15;65(8):723-7. Okelo SO, Patino CM, Riekert KA et al. Patient factors used by pediatricians to assign asthma treatment. Pediatrics. 2008 Jul;122(1):e195-201. RENAL DISORDERS Winkelmayer WC, Levin R, Setoguchi S. Associations of kidney function with cardiovascular medication use after myocardial infarction. Clin J Am Soc Nephrol. 2008 Jul 9. [Epub ahead of print]. RESPIRATORY DISORDERS Pogson ZE, Antoniak MD, Pacey SJ et al. Does a low sodium diet improve asthma control? A randomized controlled trial. Am J Respir Crit Care Med. 2008 Jul 15;178(2):132-8. Epub 2008 May 1. SOCIOECONOMIC TOPICS Weissman JS, Schneider EC, Weingart SN et al. Comparing patient-reported hospital adverse events with medical record review: Do patients know something that hospitals do not? Ann Intern Med. 2008 Jul 15;149(2):100-8. PMID: 18626049 [PubMed - in process] Hébert PC. Direct-to-consumer advertising: End the compromise. CMAJ. 2008 Jul 15;179(2):119. Kaufert P, Kaufert J. Distressing news on the therapeutics initiative. CMAJ. 2008 Jul 15;179(2):164. Mauksch LB, Dugdale DC, Dodson S, Epstein R. Relationship, communication, and efficiency in the medical encounter: Creating a clinical model from a literature review. Arch Intern Med. 2008 Jul 14;168(13):1387-95. Schommer JC, Planas LG, Johnson KA, Doucette WR. Pharmacist-provided medication therapy management (part 1): Provider perspectives in 2007. J Am Pharm Assoc (2003). 2008 May-Jun;48(3):354-63. Code on interactions with healthcare professionals. Washington DC: Pharmaceutical Research and Manufacturers of America (PhRMA); July 2008. “You’ve got drugs!” V: Prescription drug pushers on the internet. New York NY: The National Center on Addiction and Substance Abuse at Columbia University (CASA); July 2008. News release: FDA revises process for responding to drug applications. FDA News. July 9, 2008. Mello MM, Rosenthal MB. Wellness programs and lifestyle discrimination--the legal limits. N Engl J Med. 2008 Jul 10;359(2):192-9. Steinbrook R. The (slowly) vanishing prescription pad. N Engl J Med. 2008 Jul 10;359(2):115-7. Carey B, Harris G. Psychiatric group faces scrutiny over drug industry ties. New York Times. July 12, 2008. Poller L, Keown M, Ibrahim S et al. An international multicenter randomized study of computer-assisted oral anticoagulant dosage vs. medical staff dosage. J Thromb Haemost. 2008 Jun;6(6):935-43. Eckholm E. Abuses are found in online sales of medications. New York Times. July 9, 2008. Schubert C. New countermeasures considered as drug counterfeiting grows. Nat Med. 2008 Jul;14(7):700. Nussbaum A. Medco, Wal-Mart Merge Digital Prescription Networks (Correct). Bloomberg.com. July 1, 2008. Johnson C. Group calls for zero tolerance of doctor bullies. YAHOO!® NEWS. July 9, 2008. The following is a pro and con debate from BMJ: Driessen E. Are learning portfolios worth the effort? Yes. BMJ. 2008 Jul 11;337:a513. doi: 10.1136/bmj.39540.415822.AD. Norman G. Are learning portfolios worth the effort? No. BMJ. 2008 Jul 11;337:a514. doi: 10.1136/bmj.39541.449306.AD. A report found via an article in BMJ: Yadav S. Pharmacists rather than GPs should be first contact for minor ailments, report says. BMJ. 2008 Jul 11;337:a775. doi: 10.1136/bmj.a775. Inquiry report on GP access & health improvement in primary care. London: All Party Parliamentary Group Primary Care & Public Health; July 2008. The following two articles are related: Dixon A, Greene J, Hibbard J. Do consumer-directed health plans drive change in enrollees' health care behavior? Health Aff (Millwood). 2008 Jul-Aug;27(4):1120-31. Greene J, Hibbard J, Murray JF et al. The impact of consumer-directed health plans on prescription drug use. Health Aff (Millwood). 2008 Jul-Aug;27(4):1111-9. SPORTS MEDICINE Kayser B, Smith AC. Globalisation of anti-doping: The reverse side of the medal. BMJ. 2008 Jul 4;337:a584. doi: 10.1136/bmj.a584. SUBSTANCE USE DISORDERS Smith MA, Schmidt KT, Iordanou JC, Mustroph ML. Aerobic exercise decreases the positive-reinforcing effects of cocaine. Drug Alcohol Depend. 2008 Jun 26. [Epub ahead of print]. McArdle P. Use and misuse of drugs and alcohol in adolescence. BMJ. 2008 Jun 30;337:a306. doi: 10.1136/bmj.a306. The following articles are part of a four-part series in the Globe and Mail: Wente M. They're sick of watching people die: Just ask the police and doctors on the front line - harm reduction doesn't work. Globe and Mail. July 11, 2008. Wente M. We still await the scientific proof of harm reduction's success. Globe and Mail. July 14, 2008. Wente M. Europe’s approach to drugs is more enlightened … it’s tougher. Globe and Mail. July 17, 2008. Wente M. Legalization in disguise: Many harm reduction advocates believe the real harms are done by drug laws, not drugs - addicts, meanwhile, don't get the rehab they so desperately need. Globe and Mail. July 19, 2008. The following article and commentary are related: Eisenberg MJ, Filion KB, Yavin D et al. Pharmacotherapies for smoking cessation: A meta-analysis of randomized controlled trials. CMAJ. 2008 Jul 15;179(2):135-44. Ebbert JO, Hays JT. The missing link in tobacco control. CMAJ. 2008 Jul 15;179(2):123-4. VACCINES Bjorn G. Fearful of vaccines, some parents find cause for celebration. Nat Med. 2008 Jul;14(7):699. VETERINARY MEDICINE Vlahos J. Pill-popping pets. New York Times. July 13, 2008. WOMEN’S HEALTH Willers SM, Wijga AH, Brunekreef B. Maternal food consumption during pregnancy and the longitudinal development of childhood asthma. Am J Respir Crit Care Med. 2008 Jul 15;178(2):124-31. Epub 2008 Apr 10. Liu B, Beral V, Balkwill A, et all; for the Million Women Study Collaborators. Gallbladder disease and use of transdermal versus oral hormone replacement therapy in postmenopausal women: Prospective cohort study. BMJ. 2008 Jul 10;337:a386. doi: 10.1136/bmj.a386. Estrogen and progestogen use in postmenopausal women: July 2008 position statement of The North American Menopause Society. Menopause. 2008 Jun 20. [Epub ahead of print]. BY & ABOUT FACULTY/STUDENTS/ALUMNI An article by Neil MacKinnon in both English and French: MacKinnon NJ, Sanmartin C. Middle of the health care pack: Canada's performance in the 2007 Commonwealth Fund international survey. Can Fam Physician. 2008 Jul;54(7):965-6, 970-1. English, French. Mackinnon NJ, Sanmartin C. Au milieu du peloton en matiere de sante: Le rendement du Canada dans le sondage international du Fonds du Commonwealth en 2007. Can Fam Physician. 2008 Jul;54(7):970-1. THE END UNTIL NEXT TIME!!!