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Polycystic Liver Disease Or PLD


									Polycystic liver disease or PLD is the rare inherited disorder that
causes cysts to form on the liver that have the potential to decrease
liver functioning. However, most individuals who have PLD will be
asymptomatic - meaning that they will experience no symptoms - and will
not develop any serious complications from this disease.While many cases
of PLD are caused by PKD or polycystic kidney disease, there are cases
where PLD has developed in individuals who do not have PKD. Polycystic
liver disease causes cysts to form on the liver that can cause swelling
and abdominal pain in some patients.Prevalence and Symptoms of PLD
Polycystic liver disease is an extremely rare condition that affects less
than two hundred thousand individuals in the United States. While most
individuals are born with this disorder, many are never diagnosed until
they are in their mid forties to early fifties and some may never be
diagnosed due to the fact that this disease typically causes no symptoms
or serious complications.Some cases of PLD are discovered only after
image testing is done for another medical condition. The cysts that grow
with PLD are typically very small and cause no problem with liver
functioning; however, these cysts tend to grow larger in women and the
reason for this is thought to be linked with the levels of the estrogen
hormones.Typically the cysts that occur with polycystic liver disease
require no treatment. Larger cysts can cause the liver to become enlarged
(hepatomegaly) and harden causing abdominal pain. While it is rare, these
cysts may become extremely large interfering with liver function and
cause severe symptoms and serious complications that may require a liver
transplant, however, this typically not recommended unless the
complications have significantly affected the patient's quality of life
and all other forms of treatment have failed.Polycystic Kidney Disease
and its Association with Polycystic Liver Disease Over fifty percent of
individuals who develop polycystic kidney disease will also develop
polycystic liver disease, however, when PLD occurs on its own, the cysts
will typically not develop within the kidneys causing PKD. While there is
no cure or specific treatments available for either polycystic kidney or
liver disease, treatment will typically be given to control the symptoms
of the disease.When these disease coexist, treatment is typically needed
to control hypertension (high blood pressure), pain medication, or
antibiotics to treat any infections that may have occurred. In more
serious cases of polycystic kidney disease, failure of the kidneys can
occur requiring a kidney transplant.While these conditions are rare and
most go undetected due to a lack of symptoms, if you are experiencing any
symptoms that concern you, schedule an appointment as soon as possible
with your physician for an evaluation.

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