Vestergaard Frandsen About the Company Vestergaard Frandsen is an international company headquartered in Switzerland, employing 150 passionate people in 12 countries across the globe. We are the only company in the industry whose sole purpose of business is to develop lifesaving global health products and concepts. Global Presence Denmark America Switzerland Dubai India Vietnam Thailand Ghana Nigeria Kenya Indonesia South Africa Business Goals/ Model • At Vestergaard Frandsen, we are committed to the goal of basic disease prevention by providing safe drinking water and protection from malaria and other vector-borne diseases. We are especially interested in addressing a class of diseases called the Neglected Tropical Diseases (NTDs), which kill many of the most vulnerable people on earth. • Our business model is humanitarian entrepreneurship. Mission and Commitment • “With growing responsibility in global society, Vestergaard Frandsen wants to fulfill the demand for disease control textiles” - Mission Statement • Vestergaard Frandsen believes strongly in humanitarian responsibility. Our commitment to United Nation’s Millennium Development Goals drives our business objectives and provides the impetus for our continued focus on innovation. We strive towards developing life-saving tools which, when implemented together with other dedicated partners, contribute to the realization of all Millennium Development Goals. Product Portfolio • PermaNet® – PermaNet® 2.0 Long-lasting Insecticidal Net (LN) – PermaNet® 3.0 Combination Net (that kills insecticide-resistant mosquitoes) – PermaNet® Net Curtains • LifeStraw ® – LifeStraw ® Portable Water Purifier – LifeStraw ® Family Instant Microbiological Purifier • ZeroFly® – ZeroFly® Long-lasting Insecticide-incorporated Plastic Sheeting • CarePackTM – An evidence-based, basic care and prevention package designed to improve the health of HIV-infected individuals and their families PermaNet® 2.0 Long-lasting Insecticidal Net (LN) • Is a ready-to-use bednet pre-treated with deltamethrin. • Has a long-lasting killing effect on malaria mosquitoes, as well as other disease-transmitting susceptible vectors. • Is recommended by the World Health Organization (WHO) for the prevention and control of malaria. • Is made of 100% polyester, which is the preferred material by end-users. • Requires no re-treatment or dipping; thereby decreasing the need for repeat intervention. • Is based on a superior technology of impregnation, where the bioavailability of active ingredient is controlled through a slow release process. • Does not allow mosquitoes to penetrate the net due to the optimum mesh size. • Is available in various colours, shapes and sizes to accommodate local preferences. • Is the most widely tested bednet in both the laboratory and field. PermaNet® 3.0 Combination Net • PermaNet® 3.0 is a new generation long-lasting insecticidal net (LN) that has improved bioefficacy against resistant malaria mosquitoes. It combines two polymers – polyester and polyethylene – and two chemicals– Deltamethrin and a synergist (PBO) for improved bioefficacy against resistant malaria mosquitoes. • Rapid regeneration of insecticide after multiple washes ensures higher efficacy throughout the lifetime of the net. The sides and roof of the net, regenerate 100% bioefficacy after one day with susceptible Anopheles gambiae, unlike other polyethylene nets that can take up to 15 days for complete regeneration. • Unique wall construction, based on actual user behaviour, ensures longer lifetime of the net. The side panels of PermaNet® 3.0 are equipped with a specially designed lower 70cm border to enhance the lifetime of the net in the field. • PermaNet® 3.0 provides effective protection for more than 20 washes. Experimental hut studies show that mosquito mortality rates with PermaNet® 3.0 washed 20 times were better than for PermaNet® 2.0 in areas where there were resistant mosquito populations. PermaNet® Long-lasting Insecticidal Net Curtains • Ready-to-use net curtains pre-treated with Deltamethrin, an odourless and biodegradable insecticide. • Have longest-lasting killing effect on mosquitoes and houseflies. • Provide long-lasting protection for the whole household as they reduce in-house densities of the disease-transmitting vector population that cause neglected tropical diseases (NTDs) like dengue, leishmaniasis and Chagas disease. • Made of 100% polyester, which is the preferred material by end- users. • Require no re-treatment or dipping; thereby decrease the need for repeat intervention. • Available in various colours and sizes in order to accommodate local preferences. • Easy to install; require no behavior change by users. • Developed using the WHOPES-recommended PermaNet® 2.0 technology. ZeroFly® Long-lasting Insecticide-Incorporated Plastic Sheeting • Is a single solution to the dual needs for shelter and protection against vector-borne disease in complex emergencies • Contains insecticide on the surface which makes it highly effective against disease vectors such as mosquitoes carrying the malaria parasite • The use of ZeroFly® during refugee camp construction effectively reduces malaria mortality, which may account for up to 50% of all deaths in such camps • Is cost-effective as a malaria-prevention tool, as it is incorporated directly into a product that is often the first intervention in complex emergencies • Is highly valued by refugees, as plastic sheeting is essential for shelter and survival • When used on a large scale in a town or refugee camp, the product creates a „mass effect‟ that brings down the population of disease vectors in that area LifeStraw® Portable Water Purifier • Offers easy access to safer water away from home • Filters up to 1000 litres of water • Removes 99.9999% of waterborne bacteria (>LOG 6 reduction) • Removes 99.9% of waterborne protozoan parasites (>LOG 3 reduction) • Reduces turbidity by Filtering particles of approximately 0.2 microns • Contains no chemicals • Requires no electrical power or spare parts for the lifetime of the straw • Is easy to mass-distribute in areas where drinking water is contaminated LifeStraw® Family Instant Microbiological Purifier • Filters a minimum of 18,000 litres of water – provides safe drinking water for a family for three years • Has a high flow rate; offers instant access to clean water • Complies with EPA guidelines for microbiological water purifiers • Removes minimum 99.9999% of all bacteria • Removes minimum 99.99% of all viruses • Removes minimum 99.9% of all parasites • Works on highly turbid water • Does not require electrical power, batteries or spare parts for the lifetime of the product • Does not require running water • Is easy to clean, ship, carry and store CarePackTM for people living with HIV/ AIDS • Is comprised of evidence-based interventions designed to improve the health of HIV-infected individuals and their families • Includes PermaNet® long-lasting insecticidal net (LN) that can prevent malaria and other vector-borne diseases; LifeStraw® Family instant microbiological water purifier that can avert diarrhoeal diseases and printed education material providing tips on prevention of malaria, diarrhoea and sexually-transmitted diseases. Condoms for practicing safe sex and a broad- spectrum antibiotic may also be added in the CarePackTM depending on country regulations/ programme requirements • Has the potential to delay the progression of HIV to AIDS if components are used properly and continuously • Can benefit all people living with HIV, whether or not they are on antiretroviral therapy (ART), as well as their family members Integrated Prevention Demonstration Innovative Public Health Campaign Vestergaard Frandsen‟s IPD is an innovative approach that uses free distribution of public health commodities as an incentive to break social stigma attached to HIV testing. This approach was demonstrated in Kenya in September 2008. • High coverage: 81.9% of the target population attended the campaign, out of which 95% were voluntarily tested and counselled for HIV • Efficiency through scope and scale: the approach combined diarrhoea, malaria and HIV disease prevention interventions and covered more than 80% of the population within seven days • High uptake of products: 90.4% of the HIV-infected adults were using ITNs and 57.7% water filters, provided to them during the campaign • Cost effectiveness: accounting for the campaign implementation cost of $32,000 per 1000 participants, the campaign yields $13,000 in net savings per 1000 participants • Social acceptance: the approach helped people shed stigma; men come out in large numbers (>17,000 adult men participated) and there was no indication of increase in rates of domestic violence against women who tested HIV-positive • Contribution to national and international objectives: contributed to Kenya‟s national objective of 80% of adult population to know their HIV status by 2010; contributed to Millennium Development Goals by reducing the incidence of HIV, malaria and diarrhoea Research and Development • Fulfilling its commitment to reduce the global burden of disease and achieve sustainable development, Vestergaard Frandsen invests heavily in the research and development of life-saving tools. Around USD 12 million is expected to be invested from 2007 to 2010 on only vector control tools research • This allows Vestergaard Frandsen to introduce innovative vector-control solutions on a regular basis, whereas most competitors are still working with the first and only version of their products. Logistical Abilities • Vestergaard Frandsen works with a multitude of local partners to provide the exceptional service of delivering products to in- country destinations rather than simply shipping them to the container port, as is the case with most other suppliers. • We have developed a distribution network across the African continent, establishing delivery channels for deeper penetration inland and ensuring a seamless delivery to the end destination. • Vestergaard Frandsen also has warehouse facilities in the remotest parts of the world, allowing the company to help programme implementers distribute our products affordably and efficiently. • This unique profile makes Vestergaard Frandsen the optimal partner for disease-control needs.