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Scientific Review Committee Report Intel ISEF 2010


									                                   Scientific Review Committee Report

                                               Intel ISEF 2010
                                              San Jose, California

The SRC members worked on a number of projects during the year.
         • Reviewed and discussed guidelines for use of fish in research
         • Reviewed and discussed PHBA guidelines
         • Reviewed and discussed USDA pain classifications
         • Expanded Human Risk Assessment Guide
         • Expanded the online FAQ’s
         • Conducted a ISEF Rules Webinar with teachers in North Carolina
         • Responded to questions sent to
         • Responded to phone calls from students, teachers and fair directors

Projects at the Intel ISEF
The ISEF SRC reviewed the 1,258 projects pre-registered for the Intel ISEF 2010. Prior to arriving in San Jose
on Wednesday, May 5th, the committee members had reviewed and approved 1026 of the 1258 projects
received. This review involved 274 email requests requesting additional information or documentation. An
additional 135 projects were reviewed and approved before students arrived in San Jose. A total of 97 projects
required the generation of an SRC violation form.

Among the 1258 projects reviewed, 608 (48%) were conducted at a Regulated Research Institution and 269
(22%) were continuation projects. There were 574 (46%) that did not require additional forms or documentation
for specialized areas of research. Two hundred ten (37%) of these projects were conducted at a Registered
Research Institution.

Human Subjects Projects
There were a total of 110 projects (8.7%) involving human subjects. Among these projects, 35(32%) worked at
a Registered Research Institution and 42 projects required a Qualified Scientist be involved. Seventy-two (65%)
of the projects included a survey or questionnaire.

Vertebrate Animal Projects
There were a total of 46 projects (3.7%) involving vertebrate animals. Twenty-eight (61%) were conducted at a
Regulated Research Institution. Among the vertebrate animal projects were 18 projects (13 conducted in a
registered research institution) involving rats and mice and another 9 projects (3 conducted at a registered
research institution) involved fish. There were 3 amphibian projects and 3 bird projects that were observational
or behavioral studies and 2 amphibian projects that studied rDNA and the nervous system respectively. Finally,
there were nine projects involving farm animals (chickens, cows, horses and goats), a student that took a cheek
swab from her dog and a behavioral project of the food selection of tortoise.

Potentially Hazardous Biological Agent (PHBA) Projects
There were 241 projects (19%) involving potentially hazardous biological agents. These included 47 projects
involving rDNA, 168 projects involving microorganisms and 107 projects involving the use of tissue. (There is
some overlap so that projects included multiple of these areas.) Among these projects, 191 (79%) were
conducted at a Registered Research Institution.
Hazardous Substances, Devices or Activities
There were a total of 385 projects (30%) that involved the use of Hazardous Substances, Devices or Activities.
Of this total, 185 also involved one of the areas above. Two hundred fifty-six (66%) of these projects were
conducted at a Registered Research Institution.

Six projects failed to qualify for competition.
             • Three vertebrate animal studies:
                      o Student performed a procedure that is restricted to a representative of the institution.
                      o Study in which mouse weight loss exceeded permissible limit.
                      o A mouse cancer study at an institution with no analgesics.
             • A human subject study using medical records not de-identified and with no IRB review.
             • A potentially hazardous biological agents study in which students cultured bacteria and without
                 prior review or SRC approval.
             • A project exhibited at the regional fair by a team and registered for Intel ISEF by an

The committee conducted three symposia during the Intel ISEF week:
          • Meeting with the participants in the Intel Educator program – Tuesday afternoon - May 11
          • General session on rule changes followed by a question and answer period and a brief
               discussion of SRC scenarios – Wednesday morning – May 12
          • SRC 101 session – overview of rules – Wednesday afternoon – May 12

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