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What is Hypothyroidism by anamaulida

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        <p><br>Hypothyroidism is the condition in which the thyroid is
underactive (i.e., it is producing an insufficient amount of thyroid
hormones). Hypothyroidism is the most common thyroid disorder. Severe
hypothyroidism can lead to a condition called myxedema, characterized by
dry, thickened skin and course facial features.<br><br>Symptoms of low
thyroid function include:<br> <br>·   Fatigue, exhaustion, feeling
run down, sluggish, lethargic <br>·   Depression, restlessness,
moods swings, feelings of sadness, feelings of worthlessness <br>·  Â
Loss of interest in normal daily activities <br>·   Poor
concentration, poor memory <br>·   An enlarged thyroid gland
(goiter).<br>·   Modest weight gain, often 10 lb or
less.<br>·   Swelling of the arms, hands, legs, and feet, and facial
puffiness, particularly around the eyes.<br>·  Â
Hoarseness.<br>·   Muscle aches and cramps.<br><br>What causes
hypothyroidism?<br>Hypothyroidism occurs when the thyroid gland fails to
produce enough thyroid hormone. Without enough thyroid hormone, the body
becomes tired and run down. Every organ system slows, including the
brain, which affects concentration; the gut, causing constipation; and
metabolism -- the rate at which the body burns energy -- resulting in
weight gain. Although there are many different causes of hypothyroidism,
the resulting effect on the body is the same.<br><br>The most common
cause of hypothyroidism is an autoimmune disease called Hashimoto’s
thyroiditis. Normally, antibodies produced by the immune system help
protect the body against viruses, bacteria and other foreign substances.
With Hashimoto’s thyroiditis, antibodies attack the thyroid and keep it
from producing enough hormone.<br><br> GRADES OF
HYPOTHYROIDISM<br>Hypothyroidism is a graded phenomenon, ranging from
very mild cases in which biochemical abnormalities are present but the
individual hardly notices symptoms and signs of thyroid hormone
deficiency, to very severe cases in which the danger exists to slide down
into a life-threatening myxedema coma. In the development of primary
hypothyroidism, the transition from the euthyroid to the hypothyroid
state is first detected by a slightly elevated serum TSH, caused by a
minor decrease in thyroidal secretion of T4 which doesn't give rise to
subnormal serum T4 concentrations.<br><br>Diagnostic testing<br>To
diagnose primary hypothyroidism, many doctors simply measure the amount
of Thyroid-stimulating hormone (TSH) being produced. High levels of TSH
indicate that the thyroid is not producing sufficient levels of Thyroid
hormone (mainly as thyroxine (T4) and smaller amounts of triiodothyronine
(fT3)). <br>·   thyroid-stimulating hormone (TSH)<br>* free
triiodothyronine (fT3)<br>* free levothyroxine (fT4)<br>* total T3<br>*
total T4<br><br>Manifestations of Hypothyroidism<br>Hypothyroidism is a
classical disease with a classical collection of clinical signs. One
particularly well published survey of 162 confirmed hypothyroid dogs
showed the following common findings:<br>·   88% had some kind of
skin abnormality <br>·   40% had hair loss (often this starts on the
tail leading to a "rat tail" appearance or a bald area around the collar
is created) <br>·   22% had skin infection (often dogs are scaly and
smelly due to an excessively oily coat) <br><br>Hypothyroidism in
children<br>One in 4,000 babies is born with congenital hypothyroidism.
In about five per cent of cases, there's a genetic dysfunction in hormone
production. <br>Children with acquired hypothyroidism may have other
autoimmune disorders including diabetes mellitus. Both are more common in
children with Down's syndrome or Turner syndrome. It's more common in
girls than in boys.</p>        <!--INFOLINKS_OFF-->
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