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Crohn's disease


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        <h2>Crohn's disease</h2>
<h2>Crohn's disease involves inflammation of the intestine, especially
the small intestine. Inflammation refers to swelling, redness, and loss
of normal function. There is evidence that the inflammation is caused by
various products of the immune system that attack the body itself instead
of helpfully attacking a foreign invader (a virus orbacteria, for
example). The inflammation of Crohn's disease most commonly affects the
last part of the ileum (a section of the small intestine), and often
includes the large intestine (the colon). However, inflammation may also
occur in other areas of the gastrointestinal tract, affecting the mouth,
esophagus, or stomach. Crohn's disease differs from <strong>ulcerative
colitis</strong>, the other major type of IBD, in two important
<ul><li>The inflammation of Crohn's disease may be discontinuous, meaning
that areas of involvement in the intestine may be separated by normal,
unaffected segments of intestine. The affected areas are called
"regional enteritis," while the normal areas are called "skip
<li>The inflammation of Crohn's disease affects all the layers of the
intestinal wall, while ulcerative colitis affects only the lining of the
</ul><p>Also, ulcerative colitis does not usually involve the small
intestine; in rare cases it involves the terminal ileum (so-called
"backwash" ileitis).</p>
<p>In addition to inflammation, Crohn's disease causes ulcerations,
or irritated pits in the intestinal wall. These pits occur because the
inflammation has made areas of tissue shed.</p>
<p>Crohn's disease may be diagnosed at any age, although most diagnoses
are made between the ages of 15–35. About 0.02–0.04% of the
population suffers from this disorder, with men and women having an equal
chance of being stricken. Whites are more frequently affected than other
racial groups, and people of Jewish origin are between three and six
times more likely to suffer from IBD. IBD runs in families; an IBD
patient has a 20% chance of having other relatives who are fellow
<p>Crohn's disease is a chronic disorder. While the symptoms can be
improved, a patient will not be completely cured of the underlying
disease.</p>        <!--INFOLINKS_OFF-->

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