Beer-Sheva_ Israel

							Ministry of Science & Technology        Ministry of Foreign Affairs
           State of Israel                 Republic of France




     The 3rd Bi-National France-Israel Workshop

                                   on

     Biosensors, Biochips and Nanobiotechnology



    November 30-December 4, 2003



           Tentative Program
                  and
               Invitation


                    Under the auspices of
              Institute for Applied Biosciences
                              At
           The Ben-Gurion University of the Negev
                        Beer Sheva, ISRAEL
                  The 3rd France-Israel Workshop
                                 On
            Biosensors, Biochips and Nanobiotechnology
                            (With International participation)


                              Saturday 29 November 2003

                Informal evening gathering with the international guests

                          Sunday 30 November 2003

                                    INSTITUTE DAY

                                    Venue 1:
                         Goldman Auditorium, Building M5
                       The Ben-Gurion University of the Negev
                                Beer-Sheva, Israel


Registration

09:30 Front desk at the entrance of Building M5

09:50 Greetings

        Robert Marks, Chairman
        Serge Cosnier, co-Chairman

        Welcome addresses

        Avishay Braverman, President, The Ben-Gurion University of the Negev
        Jean-Christophe Auffray, Attaché pour la Science et la Technologie
        representative from the Israel Ministry of Science
        Shoshana Arad, Director, Institute for Applied Biosciences

Scientific Program

10:25 Chairperson’s introduction:
      Christian Amatore, École Normale Supérieur, Paris, France

                                      Plenary speaker

10:30 Nano-Bioelectronics for biosensors, biofuel cells, and electronic circuitry applications
      Itamar Willner, Hebrew University of Jerusalem, Israel

11:20 Coffee Break
==================================================================
Symposium on nanometer scale immobilization strategies
=============================================================

11:40 Supramolecular architecture at the electrode interface/electrolyte interface for
        biosensing applications
        Alexander Kuhn, ENS de Bordeaux, France

12:00 Assembling peptides at interfaces
      Hanna Rapaport, Ben-Gurion University of the Negev, Israel

12:20 TBA


============================================================

12:40 Lunch Buffet at the Goldman Auditorium
      Building M5 in the Lobby

==================================================================
Symposium on Biomimetic systems and interfacial design
=============================================================

14:00 The electrochemical detection of 2,4-dichlorophenoxyacetic acid
      Howard Weetal, U.S. Environmental Protection Agency, USA

14:20 Nanoscale computing devices made of biomolecules
      Ehud Keinan, Israel Technion Institute, Israel

14:40 Nano-optics in biosensors and biotechnology
      Aaron Lewis, Hebrew University of Jerusalem and Nanonics http://www.nanonics.co.il/main/

15:00 Protein-based nano-structured composite materials
      Amihai Freeman, Tel-Aviv University, Israel

==================================================================

15:20 Research directions in molecular photonics and nanophotonics at the
      D'Alembert Institute: a new crossdisciplinary venture at the crossroad of physics,
      chemistry, life sciences and device technology.
      Joseph Zyss, Institut D'Alembert (IFR CNRS 121) and Laboratoire de Photonique
      Quantique et Moléculaire (UMR CNRS 8537)


                         The Institute for Applied Biosciences
                               Building 39, Lobby Hall

16:00 Happy hour in the presence of:

        Jimmy Weinblatt, Rector
        Moti Herskowitz, Vice-President & Dean For Research and Development
        Igal Ronen, Dean of the Faculty of Engineering
        Gabi Ben-Dor, Director of the Institutes for Applied Sciences
17:00 Adjourned

17:30 Conference Bus will depart for Eilat




                         Monday 01 December 2003

                                     Change of venue:

         Ben-Gurion University of the Negev, Eilat Campus, Eilat, Israel


08:45 Bus transport from Carlton Hotel, Eilat

Registration

09:00 Front desk at the entrance of the seminar building

09:00 Poster mounting

Greetings in Eilat

09:20 Robert S. Marks, Chair, Ben-Gurion University
      Serge Cosnier, co-Chair, Université Joseph Fourier, France

Scientific Program

09:25 Chairperson’s introduction
      Nicole Jaffrezic-Renault, Ecole Centrale de Lyon, France

09:30 The L.C. Clark Plenary Lecture on Electrochemical sensors:
        Electrochemical investigations into polymerizing sol-gel systems. Modified
        electrodes from functionalized inorganic xerogels
        Pierre Audebert, ENS de Cachan, France

==================================================================
Symposium on Electrochemical sensors
=============================================================

10:00 Keynote presentation: Impedancemetric biosensors based on protein and cells
      Nicole Jaffrezic-Renault, C. Martelet, L. Ponsonnet; Ecole Centrale de Lyon, France

10:20 Amperometric biosensor for on-site monitoring
      Judith Rishpon, Tel-Aviv University, Israel

10:40 Polyluminol polymerization and its use in biosensors
      Andres Novoa, Ben-Gurion University of the Negev

11:00 Biotinylated polymers: application to the elaboration of bioanalytical devices
      Serge Cosnier, Université Joseph Fourier, France
11:20 Real-time investigation of biosensors during their operation
      Barna Kovacs, University of Pecs, Hungary

11:40 Studying lateral charge propagation by SECM
      Daniel Mandler, Hebrew University of Jerusalem, Israel

==================================================================


12:00 Lunch

13:25 Chairperson’s introduction
      Jiri Homola, Institute of Radio Engineering and Electronics, Czech Republic

13:30 Probing molecular media by nonlinear optics and luminescence at the micro-
       and nanoscale: recent results and applications perspective in information and
       bio technologies
       Joseph Zyss, Institute D'Alembert (IFR CNRS 121) and Laboratoire de
       Photonique Quantique et Moléculaire (UMR CNRS 8537)

==================================================================
Symposium on Optical bio-sensors
=============================================================

14:00 Keynote lecture: Advances for SPR Biosensing
      Jiri Homola, Institute of Radio Engineering and Electronics, Czech Republic

14:20 Novel distributed biochemical fiber Bragg sensors
      Moshe Horowitz, Israel Technion Institute, Israel

14:40 New colorimetric biosensors for bacterial analysis
       Raz Jelinek, Ben-Gurion University of the Negev, Israel

15:00 Fluorescence-Based Biosensor for Early Detection of Explosives
      Vladislav Papper, Ben-Gurion University of the Negev, Israel and PheroCap Ltd

15:20 Indium tin oxide-coated fiber-optic immunosensors
      Robert S. Marks, Ben-Gurion University of the Negev, Israel

==================================================================

==================================================================

15:40 Poster Viewing and Tea party (goûter)

01     Leshem et al.; Silane-benzophenone-coated fiber-optics for the development of immunosensors
02     Polyak et al.; Biotin-alginate as a matrix for biosensor applications
03     Konry, T. et al; Indium tin oxide-coated fiber-optic immunosensors to Hepatitis C via pyrrole-benzophenone
       immobilization
04     Lavi, Y.; Dynamic nanoclusters on cell membranes
05     Freifeld, Z. et al., Magnetic Immuno-Phage Assay for the monitoring of Listeria monocytogenes
06
07     Herrrmann, S. et al. Detection of West Nile virus using a fiber-optic immunosensor
08     Green, T. et al.; Monitoring heavy metals using a whole-cell fiber-optic biosensor
09
10
11
12
13
14
15      Ionescu et al.; Amperometric immunosensor to cholera antitoxin
16
17
18
19
20
=============================================================

19:00 Welcome Diner

Social activity

21:00 Open Bar at the Carlton Hotel




                              Tuesday 02 December 2003

09:10 Bus transport from Carlton Hotel, Eilat

Scientific Program

09:25 Chairperson’s introduction:
      Thierry Livache, Leti, Centre d’Énergie Atomique, Grenoble, France

09:30 TBA


==================================================================
Symposium on Micro-arrays, Biochips AND Micro-Bio-Analytical Systems
=============================================================

10:00 Keynote presentation: A microfluidic chip for whole cell integration
      Yosi Schaham, Tel-Aviv University, Israel

10:40 Neuro-Processors: VLSI Chips for Sensing and Processing of In-Vivo and In-Vitro
      Neuronal Signals
      Ran Ginosar, Israel Technion Institute, Israel

11:00
        Thierry Livache, Leti, Centre d’Énergie Atomique, Grenoble, France

11:20 TBA


12:00 Genechips and microarrays, genomes and beyond
      Amos Grundwag, Affymetrix product manager in Israel

=============================================================

12:20 Lunch
Scientific Program

13:15 Chairperson’s introduction:


==================================================================
Symposium on NanoBiosystems
=============================================================

13:20 Regulation of a microtubule-based motor protein
      Larisa Gheber, Ben-Gurion University of the Negev, Israel

13:40 Dynamic state diagram of actin-based motility
      Anne Bernheim-Groswasser, Ben-Gurion University of the Negev, Israel

14:00 Dynamics of Biopolymers In and Out of Equilibrium
      Rony Granek, Ben-Gurion University of the Negev, Israel

=============================================================

Social activity

14:30 Jeep Tour
      (Thick sweater and heavy coat will be required for the cool evening)

19:40 Middle-Eastern Dinner in a desert refuge

       Story-telling
       Drummer

21:00 Jeep Tour

       Search for desert animals by night on the way back to the hotel


                              Wednesday 03, 2003

09:10 Bus transport from Carlton Hotel, Eilat

Scientific Program

09:25 Chairperson’s introduction:


09:30 The Richard Feynman Plenary Lecture on Nanotechnology
      Molecular Scale Electronics Assembled by DNA and Proteins
      Uri Sivan, Israel Technion Institute, Israel

==================================================================
Symposium on Nanobiotechnology
=============================================================
10:00 Keynote presentation:
      Christian Amatore, École Normale Supérieur, Paris, France

10:40 Nano-patterning biomolecules and bio-surfaces with SPM
      Levi Gheber, Ben-Gurion University of the Negev, Israel

11:00 Single molecule studies of DNA relaxation using optical tweezers
      Mario Feingold, Ben-Gurion University of the Negev, Israel

11:20 TBA

11:40 Mono/oligo-nucleotide recognition on monolayers of complementary polymer films
      Amir Berman, Ben-Gurion University of the Negev, Israel

12:00 Dynamics of DNA fluctuations
      Oleg Krichevsky, Ben-Gurion University of the Negev, Israel

==================================================================

Lunch

Scientific Program

==================================================================
Symposium on the application of Nanobiotechnology and Biosensors
=============================================================

14:00 Continuous Non-invasive Glucose Monitoring Through Ultrasonically Permeated Skin
      Yossi Kost, Ben-Gurion University of the Negev, Israel

14:30 Nanolayers Ltd
      Shlomo Ytzchaik, Hebrew University of Jerusalem

15:00 Array of micro-needles
      Shuki Yeshurun, NanoPass Ltd

15:30 TBA

16:00 Capsule endoscopy: present-future
      Gabi Iddan, Given Imaging Ltd

16:30 TBA

=============================================================


                                 Forum: Biomed Israel

17:00 Panel discussion theme: Transfer of technology in Nanobiotechnology
      Animateur: Didier Toubia
      Chairmen:      Maurice Sportiche, Chef de la Mission Économique, Ambassade de
                     France
                     Jean-Christophe Auffray, Attaché pour la Science et la Technologie,
                     Ambassade de France
       Panel: Raz Jelinek, Member of the Ilse Katz Center for Meso- and Nano-scale
              Science
              and Technology, Ben-Gurion University of the Negev
              Ron Maron, Managing Director, University Research Institute for Nano-
              Science and NanoTechnology, Tel-Aviv University
              Uri Sivan, The Sara and Moshe Zisapel Nano-electronics Center at the
              Israel Technion Institute [www.ee.technion.ac.il/nano]

       Discussion points:              Intellectual property
                                       Israeli success stories
                                       The incubators program

           Farewell cocktail at the invitation of the French Embassy in Israel


20:00 Awards of Excellence for the Best Poster:
      Chairman: Amir Berman, Ben-Gurion University of the Negev


20:05 Evaluation of the poster contributions by the Poster Award Committee

       Rapporteur: TBA

20:20 Award to the best Poster winner (student under 30) of a return Air France
      plane ticket (Paris-Tel-Aviv-Paris)

                                    Workshop lecture:

20:30 Anecdotes in bioaffinity
      Meir Wilchek, The Weizmann Institute of Science, Israel




                               Thursday 04, 2003

08:00 Breakfast

Scientific Program

Chairman: Shimshon Belkin, Hebrew University of Jerusalem, Israel

09:25 Chairperson’s introduction:

09:30 TBA


==================================================================
Symposium on Bio-reporter cells
=============================================================

10:00 Whole-cell bacterial sensors for the detection of heavy metals
      Kaisa Hakkila, University of Turku, Finland
10:20 Monitoring genotoxicity during the photocatalytic degradation of para-nitrophenol
      Shani-Sekler, Michal, Ben-Gurion University of the Negev, Israel

10:40 Biotinylated dentrifying bacteria and their electrochemical monitoring
      Serge Da Silva, Université Joseph Fourier, Grenoble, France

11:00 Whole cell biochips for toxicity detection
      Shimshon Belkin, Hebrew University of Jerusalem, Israel

11:20 Recent and less recent progress in sol-gel biosensing
       Ovadia Lev, Hebrew University of Jerusalem, Israel

==================================================================

12:00 Lunch



                                  Workshop conclusions

Robert S. Marks, Ben-Gurion University of the Negev, Israel


Workshop closes

14:00 Bus back to Beer-Sheva
Main organizers and sponsors:

The workshop is organized and supported by both the Israeli Ministry of Science,
Culture and Sport and by the French Ministry for Foreign Affairs. The workshop will
be held under the auspices of the Institute for Applied Bio-Sciences, at the Ben-
Gurion University of the Negev.


Conference venues

Important: There are 2 venues!

November 30, 2003

Goldman Auditorium
Ben-Gurion University of the Negev
Building M5, Seminar room
Beer-Sheva, Israel

December 01-04, 2003:

The Ben-Gurion University of the Negev, Eilat Campus, Eilat, Israel



                        Congress fees and Method of Payment:

There are registration fees for the Conference at the Eilat Campus (Eilat) venue only.
The payment must follow the registration form. Remittances should be free of bank
charges to the receiver, and should be paid by the participant. The registration form
must indicate which means of payment you have used. All payments must be clearly
marked with the delegate’s name and “3-FIBBN”

Student:                        $200.00

Academic:                       $250.00

Industry:                       $350.00

Accompanying person:            $150.00


The registration fees give admission to the meeting, including access to all the
lectures, poster session, all social activities, the book of abstracts, lunches, all coffee
breaks and conference transportation.

We are sorry that no refunds are possible.
Scientific and Coordinating Committee

    Robert S. Marks
    Serge Cosnier


Local Organizing Committee and their duties

 Arad, Shoshana, BGU            organisation                arad@bgumail.bgu.ac.il
 Berman, Amir, BGU              abstracts and posters       aberman@bgumail.bgu.ac.il
 Geber, Levi, BGU               happy hour, web-site        glevi@bgumail.bgu.ac.il
 Marks, Robert, BGU             chair                       rsmarks@bgumail.bgu.ac.il
 Shani-Sekler, Michal, BGU      administrative              shanisek@bgumail.bgu.ac.il
 Toubia, Didier                 BioMed                      didier@toubia.com
 Van Zwaren, Joe, MOST          publication of abstracts    jo@most.gov.il
 Shimony Zanglevich, MOST       Administrative aspects of   becky@most.gov.il
                                the French guests


Conference administrative contact:

    Shani-Sekler, Michal
    Institute for Applied Biosciences, Ben-Gurion University of the Negev
    POBox 653, Beer-Sheva 84105, Israel
    972-8-6479048; 972-54-755492
    shanisek@bgumail.bgu.ac.il


Key dates to remember

      The Symposium will be held on 30 November-4 December 2003
      Abstracts are due by 3 November 2003
      Registration* by 3 November 3002 ‫‏‬

      *late registration (after November 3, 2003) will incur an extra $50.00


Target audience

The workshop should prove useful for all researchers working at related areas in the
Academia as well as Industry, at levels ranging from beginners (advanced Ph.D.
students or equivalent) to senior researchers. The round table at the closing of the
conference should be of particular interest also to policy makers and management at
both communities.
Scientific Program

The scientific program includes invited presentations, a round table discussion panel
and a poster session open to all who register. The submission of topics is open to all
working in the aforementioned fields.

Language

The official language of the Workshop will be English.

Poster Session

A contributed poster session open for all on biosensors, biochips and nano-
biotechnology projects, is being organized in order to enable interaction between the
scientists. The organizing committee wishes to urge researchers from these fields to
submit their work to this session.

Abstracts Deadline: 3 November 2003

The abstracts booklet will be distributed to the symposium participants and to the
public and be posted on the website of the Institute for Applied Bio-Sciences.
www.bgu.ac.il/IAB/

Conference Proceedings and publications:

Abstract submission:
The Scientific Committee invites you to submit abstracts of papers to be considered
for oral and poster presentations. The submission deadline is November 3, 2003. The
committee requests that you follow the following simple procedures. Please send the
abstracts in MS word format (.doc) as an attachment, to either Serge Cosnier
serge.cosnier@ujf-grenoble.fr or Robert S. Marks rsmarks@bgumail.bgu.ac.il and
indicate if you prefer an oral communication or a poster presentation. You may also
send it by fax to 972-8-6472857 to ensure accurate reproduction of your text. Authors
will be notified on the Scientific Committee’s decisions on the acceptance of their
abstract (s) and on the form of presentation within two weeks of receipt of the
abstract. Authors will be informed about the schedule of their contributions in due
time.

Abstracts must be sent in electronic form, single-spaced, according to the following
instructions:

      Keep abstract in a single A4 page and use 3cm for all margins
      Use Arial font size 10 along the text with a 1.5 spacing
      Type the title in CAPITAL BOLD letters and center it
      Leave one line between the authors (also centered) and the title
      Underline the name of the presenting author
      Type the institutional addresses of all authors immediately below the names
       with a two-line spacing
      Add the email of the speaker and if applicable the home page URL of the
       principle author
      Leave two lines between the address and the text
      Leave one line between the text and any references


Guideline for poster
Maximum poster size is 1 meter wide by 1.2 meters long.

Student poster award
Conditions of entry are that the student applicant appears as first author on the poster.
Your registration form must clearly demonstrate that you are a student with the
supervisor’s name. Applicants are required to be enrolled as a student in a BSc, MSc
or PhD program.

Proceedings submission:
The official proceedings journal is Talanta and January is the deadline for an
electronic submission.

Hotel:
A great price was negotiated for this conference at the Prima Carlton Hotel, Eilat.
   1. 170 NIS per night per single room on a bed and breakfast basis
   2. 200 NIS per night per double room on a bed and breakfast basis
   3. Extra nights for the week-end will incur an extra 50 NIS per night (for a
       minimum 2 nights)

Childcare:

Exhibition:
Companies will be given a space to display their wares. Please contact Michal Shani-
Sekler at shanisek@bgumail.bgu.ac.il.

Event
We are happy to announce that December 8 and 9, 2003, the International Symposium
on Bio-inspired Engineering will take place in Haifa, Israel. You may find more
information at: http://www.entersymposium.com/ISBIE/1

.
              3rd Bi-National France-Israel Workshop on
              Biosensors, Biochips and Nanobiotechnology
                        Beer-Sheva and Eilat, ISRAEL
                        November 30-December 04, 2003
                          REGISTRATION FORM
             The enclosed registration form should be returned in advance to:

                            Haya Blum, Eilat Campus
                            hbulm@bgumail.bgu.ac.il
                              972-8-6304536 (voice)
                               972-8-6304551 (fax)
                          Kindly use one form per participant
                    Do not forget to make a copy for your own record
Please complete where applicable:
      I shall attend the meeting alone
      I shall be accompanied by                                      non-participants

Total Price: ___________________
Surname:                             First name:                       Title:

ID / Passport No. & Country:

Address and Zip Code:

Tel:                                  Fax:                   Email:

PAYMENT OPTIONS:
1. Credit card type:                               Name:

Card number:                                    Expiration date:

Signature:


2. BANK TRANSFER:
Bank Hapoalim 012, Branch 547, account number 6500 (cite: conference Biosensors)
           Fax copy of bank transfer with this form to Haya Blum
3. CASH ON SITE: (50 USD late fee)
HOTEL PRIMA CARLTON EILAT RESERVATION FORM
       ROOMS RESERVED UNTIL OCTOBER 30, 2003 ONLY!!!!!!!!!!!!!!!
                    Kindly use one form per participant
              Do not forget to make a copy for your own record

                        3rd Bi-National France-Israel Workshop on
                       Biosensors, Biochips and Nanobiotechnology

                           Beer-Sheva and Eilat, ISRAEL
                           November 30-December 04, 2003

Please complete where applicable:

      Single Room (170 NIS per night bed and breakfast)
      Double Room (200 NIS per night bed and breakfast for two)
      Extra night for the week-end (incurs an extra 50 NIS per night for 2 nights minimum)

      Number of nights: _____________ Total Price:______           __________

Surname:                             First name:                      Title:

ID / Passport No. & Country:

Address and Zip Code:

Tel:                                 Fax:                  Email:

PAYMENT BY CRESIT CARD ONLY

1. Credit card type:                               Name:

Card number:                                    Expiration date:

Signature:


Please send the reservation form to Esther - The Reservation Manager at Prima
Carlton Hotel Eilat:

Email: carleilat@prima.co.il; Fax: 972-8-634196; Voice: 972-8-6388555

        All reservations need to be confirmed by the Hotel!
                                        ‫אישור כניסה‬

                    .30.11.03 ‫מסמך זה מהווה אישור כניסה לאוניברסיטת בן-גוריון בתאריך‬

               ‫מחזיק אישור זה הינו מוזמן לכנס " הדו לאומי השלישי ישראל צרפת בנושא‬
               ‫ביו-חיישנים, ביו-שבבים וננוביוטכנולוגיה" שנערך ע"י המכון למחקר יישומי‬
                                                                       .‫במדעי החיים‬




                            ENTRANCE PASS

     This document entitles the bearer to enter the Ben-Gurion University of the
     Negev on 30.11.03 as a one-day pass.


                                                   rd
     The bearer has been invited to attend the “3 France-Israel Workshop
     on Biosensors, Biochips and Nanobiotechnology” organized by the
     Institutes for Applied Biosciences.




The authorization was given by: Zvi Schwartz                ‫האישור ניתן ע"י צבי שוורץ- ממ"ח בטחון‬
Phone number: 08-6461553                                                        5551443-00 :‫טלפון‬

     THE BEN-GURION UNIVERSITY OF THE NEGEV
                                    8                   8
The‫‏‬Camous Map




Legend:

M5 Goldman Auditorium at the school of medicine building
7-10 Parking lots