MCQs - Inflammation by shrihareesh


1.The process of phagocytosis was first described by
 a.Celsus            b.John Hunter
 c.Virchow           d.Elie Metchnikoff.
2.--------- is the hall mark of acute inflammation
a.Increased vascular permeability                  b.Chemotaxis
c.Leucocyte adhesion                               d.Phagocytosis.
3.Transmigration of cells across the endothelium is called as
 a.margination               b.diapedesis
 c.chemokinesis            d.chemotaxis
4.One of the flowing is NOT a chemoattractant
 a.C5a                       b.Leucotriene C4
 c.Leucotriene B4            d.Interleukin -8
5.The free radical generated in H202-MPO-Halide system is
 a.HOCl       b.O2           c.H2O2         d.OH
6.Major basic protein is produced by
 a.Neutrophil b.Basophil            c.Monocyte           d.Eosinophil.
7.Chediak-Higashi syndrome is characterized by all EXCEPT
a.Defective degranulation b/Delayed killing
 c.Neutrophilia                     d.Giant granules
8.Aspirin acts by inhibiting -------- enzyme
a.cyclooxygenase             b.lipooxygenase
c.phospolipase               d.synthetase
9.All the following chemical mediators cause vasodilatation EXCEPT
 a.Prostacyclin I2           b.Thromboxane A2
 c.Prostaglandin E2 d.Prostaglandin D2
10.Nitric oxide is usually synthesized from
  a.L-cysteine               b.L-arginine
  c.Methionine               d.L-lysine.
11.Splenic macrophages are usually referred as
 a.Littoral cells            b.Langhans cells c.Langerhans cells         d.Reticulum cells.
12.The most important cytokine involved in the formation of an epitheloid
   cell is
   a.Interleukin -8                 b. Beta Interferon
   c. Gamma Interferon              d.Interluekin - 2
13.The most common pattern of inflammation seen in rheumatic pericarditis is
a.Serofibrinous       b.Catarrhal              c.Purulent             d.Membranous
14.Touton giant cells are usually seen in ------- infection.
a.Xanthomatous               b.Syphilis                    c.Fungal   d.Schistosomal
15.All of the following are stable cells EXCEPT
 a.Hepatocytes        b.Hemopietic cells       c..Fibroblasts         d.Endothelial cells
16.One of the following is a most important angiogenic growth factor
 a.Epidermal growth factor          b.Fibroblast growth factor
 c.Platelet derived growth factor d.Transforming growth factor -beta
17.The most characteristic feature in healing by secondary intention is
 a.Intense inflammation             b.Excessive granulation tissue formation
 c.Wound contraction                d.Larger tissue defects
18.One of the following vitamin deficiency causes delayed wound healing
 a.A          b.D            c.K               d.C.
19.One of the following is NOT a granulomatous disease
a.Leprosy             b.Tuberculosis           c.Salmonellosis d.Sarcoidosis.
20.One of the following is a cell derived chemical mediator
a.Membrane attack complex           b.Fibrinopeptides c.Bradykinin           d.Platelet activating factor

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