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                                    CURRICULUM VITAE

                                   Harry Leon June, Ph.D.

                                  Professor of Psychiatry
                               Director of Substance Abuse
                Professor of Pharmacology and Experimental Therapeutics
                        University of Maryland School of Medicine

                                     December 10, 2010

OFFICE ADDRESS:
University of Maryland School of Medicine
Department of Psychiatry
110 S. Paca St, 4th Floor
Baltimore, MD 21201
Phone: (410) 706-40001
Cell: 317-496-7389
Fax: (410) 706-4002
Email: hjune@psych.umaryland.edu
http://medschool.umaryland.edu/Psychiatry
English (Native)

Neuropsychopharmacology
Laboratory: (410) 706-4019


EDUCATION:
1975-1979  B.S., Psychology/Biology, South Carolina State College, Orangeburg, SC
1982-1984  Practicum Student, Howard University, Child Development Ctr, Washington, DC
1982-1986  M.A., Clinical Psychology, University of the District of Columbia, Washington, DC
1983-1987  M.S., Physiological Psychology, Howard University, Washington, DC
1989-1990  Consortium Research Fellow in Database Development, Basic Research Laboratory,
           U.S. Army Research Institute for the Behavioral and Social Sciences, Alexandria, VA
1987-1990  Ph.D., Physiological Psychology/Animal Psychopharmacology, Minor: Personality
           Psychology, Howard University, Washington, DC

POST GRADUATE EDUCATION AND TRAINING:
1989-1992 Postdoctoral Fellowship in Clinical Psychopharmacology, Behavioral Pharmacology
          Research Unit, Department of Psychiatry, Johns Hopkins University /Francis Scott
          Key Medical Center, Baltimore, MD

       Research Experience:
       1984-1986   Research Associate, University of the District of Columbia, Agriculture
                   Experimental Station, Mother-Infant Longitudinal Bonding Study.
       1985        Research Assistant, University of the District of Columbia, Center for
                   Applied Research and Urban Policy, Teenage Pregnancy Study.
       1987-1989   Field Research Coordinator, University of the District of Columbia,
                   Agriculture Experimental Station, District of Columbia Street Homeless
                   Project.
                                                                                                2

       1983-1989     Graduate Research Assistant, Howard University, brain stimulation reward,
                     neurobiobehavioral effects of ethanol, conditioned taste aversion paradigms,
                     feeding and drinking behavior, spontaneous activity measures.
       1989-1992     Postdoctoral Researcher, Behavioral Pharmacology Research Unit,
                     Department of Psychiatry, Johns Hopkins University, responsibile for writing
                     and implementation of research protocols investigating the
                     psychopharmacodynamics of opioid withdrawal and dependence and the
                     assessment of pharmacotherapeutic agents for the treatment of opioid
                     dependence in human drug abusers.

       Clinical Experience:
       1980-1980     Weekend Relief Counselor, Montgomery County Association for Retarded
                     Citizens, Kensington, MD, adult mental retardation.
       1981-1982     Therapeutic Educational/Recreational Specialist, St. Elizabeth’s Hospital,
                     Washington, DC, psychiatric and severe mental retardation
       1982-1983     Psychological Assistant, St. Elizabeth’s Hospital, Washington, DC,
                     psychological testing, behavioral and reality oriented therapy.
       1982-1984     Practicum Student, Howard University, Child Development Center,
                     Washington, DC, infant and child psychodiagnostics
       1984-1985     Mental Health Worker, Alexandria Hospital, Alexandria, VA, psychiatric
                     emergency
       1982-1988     Residential Counselor, National Children’s Center, Washington, DC, child
                     and adolescent mental retardation and emotional distrubance.
       1983-1989     Grduate Researcher, University of the District of Columbia, evaluation of
                     teacher styles in educationally handicapped students
       1989-1992     Postdoctoral Researcher, Behavioral Pharmacology Research Unit,
                     Department of Psychiatry, Johns Hopkins University, responsibile for writing
                     and implementation of research protocols investigating the
                     psychopharmacodynamics of opioid withdrawal and dependence and the
                     assessment of pharmacotherapeutic agents for the treatment of opioid
                     dependence in human drug abusers.

EMPLOYMENT HISTORY:
1982-1985    Graduate Teaching Assistant, University of the District of Columbia, Department of
             Psychology
1983-1990    Graduate Teaching Assistant, Howard Unversity, Department of Psychology
1986-1988    Assistant Professor, University of the District of Columbia, Department of
             Psychology
1990-1992    Adjunct Lecturer, University of Maryland, Baltimore County, Department of
             Behavioral Medicine, Catonsville, Maryland
1993-1996    Adjunct Lecturer, Martin University, Department of Psychology Indianapolis, Indiana
1993-1998    Assistant Professor, Indiana University School of Medicine, Medical Neurobiology
             Program, Indianapolis, Indiana
1992-1998    Assistant Professor, Indiana University-Purdue University, Department of
             Psychology, Indianapolis, Indiana
1998-2003    Associate Professor, Indiana University School of Medicine, Medical Neurobiology
             Program, Indianapolis, Indiana
1998-2003    Associate Professor, Indiana University - Purdue University, Department of
             Psychology, Indianapolis, Indiana
2003-Present Professor, Indiana University School of Medicine, Medical Neurobiology Program,
             Indianapolis, Indiana
                                                                                           3

2003-2005    Professor, Indiana University - Purdue University, Department of Psychology,
             Indianapolis, Indiana
2005-Present Professor, University of Maryland School of Medicine, Department of Psychiatry
2005-Present Director of Substance Abuse, University of Maryland School of Medicine,
             Department of Psychiatry
2005-Present Professor, University of Maryland School of Medicine, Department of Pharmacology
             and Experimental Therapeutics

PROFESSIONAL MEMBERSHIPS:
1989      Society for Neuroscience
1990      Research Society on Alcoholism
1992      Behavioral Pharmacology Society
1992      International Society of Biomedical Research on Alcoholism
1998-2003 Associate Member, American College of Neuropsychopharmacology
2003      Member, American College of Neuropsychopharmacology

HONORS and AWARDS:
1987-1990 Minority Biomedical Research Support Fellowship [Graduate School]
1988      Patricia Harris Biomedical Research Award [Graduate School]
1991      NIDA Travel Award: Committee on Problems and Drug Dependence
          [Postdoctoral]
1991-1994 American College of Neuropsychopharmacology Minority Travel Award
          [Postdoctoral]
1994-1998 American College of Neuropsychopharmacology Mead Johnson Travel Award
          [Assistant Professor]
1997      Indiana University-Purdue University School of Science Research Award
          [Assistant Professor]
1998      Chancellor’s Bynum P. Mentorship Award, Indiana University-Purdue University
          [Associate Professor]
1998      Psychology Mentorship Award, Indiana University-PurdueUniversity
          [Associate Professor]

INSTITUTIONAL SERVICE
1994-present     Member, Minority Research Scholars Committee
1994- present    Member, Psychobiology Curriculum Committee
1996             Member, Search Committee for Clinical Rehabilitative Psychology Faculty
1998             Member, Promotion and Tenure Committee, Department of Psychology
1994-2002        Member, Short-Term Training Program for Minority Students Interested
                 In Biomedical Research Committee
1995-2003        Co-Coordinator Psychology Undergraduate Research Committee
2002-present     NIAAA Training Grant Committee Member (IU School of Medicine)
                 for Selection of Predoctoral and Postdoctoral Applicants
2003             Bepko Chancellor Scholarship Committee

OTHER INSTITUTIONAL SERVICE: MASTERS THESES AND PH.D. DOCTORAL
THESES COMMITTEE :
1992-94          Chair, Master's Thesis Committee in Psychobiology, Robert L. Hewitt:
                 Tolerance Development to the Ethanol Suppressant Effects of the
                 Benzodiazepine Inverse Agonist RO19-4603 (completed).
                                                                                               4

1992-95             Member, Ph.D. Dissertation Committee in Medical Neurobiology, Simon
                    Kanter: Muscurinic Receptor Involvement in Alcohol Drinking and Behavioral
                    Activity of Alcohol-Preferring (P) and-Nonpreferring (NP) Rats (completed).

1994-1997           Chair, Master's Thesis Committee in Psychobiology, Charity R. Cason:
                    GABAergic Modulation of the Reinforcing Properties of Alcohol
                    (completed).

1999-2002           Chair, Master's Thesis Committee in Psychobiology, Katrina L. Foster: A
                    Systematic Evaluation of GABAA and Opioid Receptors of the Central
                    Nucleus of the Amygdala in Regulating Ethanol and Sucrose-Maintained
                    Responding (completed).

2000-2003           Chair, Master's Thesis Committee in Psychobiology, William JA Eiler II:
                    The D1 Dopamine Receptor Regulates Alcohol-Motivated Behaviors in the
                    Bed Nucleus of the Stria Terminalis in Alcohol-Preferring (P) Rats
                    (completed).

2001-2004           Chair, Master's Thesis Committee in Psychobiology, Hardy, L., Responding
                    for Brain Stimulation Reward (BSR) in the Bed Nucleus of the Stria
                    Terminalis (BST) in High Alcohol Drinking (HAD) and Low Alcohol Drinking
                    (LAD) Rat Lines (April 2004 completed).

1999-2004           Chair, Ph.D. Dissertation Committee in Psychobiology, Foster, K.L: The
                    role of the GABAA 1 subtype in mediating the neurobehavioral effects of
                    alcohol: studies using the 1 KO and WT mice (July 2004 completed).

2000-2004           Chair, Ph.D. Dissertation Committee in Psychobiology, Woods, J.E. II: The
                    D1, but not the D2 dopamine receptors in the nucleus accumbens regulate
                    the BSR threshold lowering effects of amphetamine in high alcohol drinking
                    (HAD)-1 rats (November 2004 completed).


NATIONAL SERVICE:

Adjunct Reviewer, Neurotoxicology and Alcohol Study Section [NAL] Intergrative, ( NIAAA)
  February 3, 2010, Grant Reviewer

Member, AA-1 Review Committee for National Institute of Alcoholism Abuse and
Alcoholism (NIAAA)
   July 20, 2002-2006, Grant Reviewer

Member, Merit Review Subcommittee for Alcoholism, Drug Dependence, Anesthesiology and
Analgesia (Veterans Administration)
  March 15, 2002-2003, Grant Reviewer

Ad Hoc JOURNAL REFEREE:
   Journal of Neuroscience, Neuropsychopharmacology, Synapse, Alcoholism:Clinical and
   Experimental Research, Pharmacology, Biochemistry and Behavior, Psychopharmacology,
   Behavioural Pharmacology, Brain Research-Molecular Section, Proceedings of the National
  Academy of Sciences
                                                                                                      5


TEACHING SERVICE (see below):

         Behavioral Neuroscience [615] focuses on cellular, systems, and cognitive aspects of
behavior. Behavioral Neuroscience is the initial core class that 1st year Ph.D. Psychobiology
students are required to enroll in. Following the 615 class, graduate students are expected to
enroll in Psychopharmacology [618]. Psychopharmacology is a class that focuses on the study of
drugs and behavior in relation to neuropsychiatric disorders and drug dependence. A large focus
of the class is on the molecular, neurobiological, and neuropharmacological aspects of
neuropsychiatric disorders and drug dependence. The Drug Abuse [590] class represents an
advanced class of the Ph.D. Psychobiology of Addictions curriculum. The class focuses on
current methodological approaches and theoretical analyses that are used by today’s
neuroscientists in understanding drug addiction. While the class was previously divided into 2
semesters, it is now a 1 semester class. Dr. June teaches the class by inviting “esteemed”
neuroscientists from neighboring states, IU Medical Neurobiology Program, Eli Lilly and across the
country to provide lectures. Drs. June and Goodlett also provide lectures. When notable speakers
were brought in from Eli Lilly and across the country, Dr. June coordinated a university wide
“Psychobiology Lecture Series”. The Psychobiology of Motivation and Reward [544] class is a
specialty class wherein Dr. June teaches about the neurobiology of motivated behaviors. The
class focuses on understanding the neuoanatomical substrates of motivated behavior. Equally
important, the class provides the students with an understanding of past and present theories of
reward and reinforcement. Due to the interdisciplinary nature of many of these classes and their
clinical relevance, several are appealing to Clinical Rehabilitation, Medical Neurobiology, and
some social work Ph.D. students. Medical school M.D./Ph.D. students are also often enrolled in
several of the classes. Finally, Graduate Seminar [591] is a literature topic class wherein both
graduate students in Psychobiology and Medical Neurobiology convene to discuss current
literature in the drug abuse field. It is also important to note that several of these classes are cross
referenced within the Medical Neurobiology Program curriculum in the Dept. of Psychiatry, IU
School of Medicine.

       B320, Behavioral Neuroscience [formerly known as Physiological Psychology] is an upper
level undergraduate psychology class designed to teach students about the physiological
processes regulating psychological behavior with emphasis placed on both the central and
peripheral nervous systems. As with the graduate class, this class focuses on cellular, systems,
and cognitive aspects of behavior. The teaching format comprises a lecture-seminar format and
students are routinely asked to verbally contribute to the class during lectures. Exams are 70%
essay, and a topic paper is written and presented by the students to their peers. The topic paper is
10-15% of the student's total grade. Brain Mechanisms [B452] SP2004 is an advanced
undergraduate class which deals with cellular diversity within the CNS, and the role of various
second and third messenger systems in regulating motivated behavior as well as learning and
memory. Finally, the 105 class as noted below in an introductory class that Dr. June teaches every
3 years.
                                                                                                 6


Classes Taught at IUPUI Psychology Department
_______________________________________________________________________________

Name of course        Semester       G/U    Course #       Time Spent in Classroom
                                                           N
                                                           during a 16 week semester
________________________________________________________________________________

Psychopharmacol       Fall 93        G      B618           11             2.5 hr
Physio Psy            Fall98         U      B320           12             2.5 hr
Physio Psy            SP98           U      B320           19             2.5 hr
Intro to Psych        Sum98          U      B105           19             4.5 hr
Physio Psy            Sum98          U      B320           5              4.5 hr
Physio Psy            Fall99         U      B320           18             2.5 hr
Psycho Motivation     SP99           G      B544           6              2.5 hr
Physio Psy            Fall2000       U      B320           18             2.5 hr
Intro to Psych        Fall 2000      U      B105           52             2.5 hr
Drug Abuse            SP2000         G      B590           6              2.5 hr
Behav Neurosci        Fall 2001      G      B615           14             2.5 hr
Physio Psy            SP2001         U      B320           22             2.5 hr
Behav Neurosci        SP2002         U      B320           22             2.5 hr
Drug Abuse            Fall2003       G      B590           8              2.5 hr
Brain Mechanisms      SP2004         U      B452           4              2.5 hr
of Behavior
Graduate Seminar      SP2004         G      B591           9              2.0 hr
Psycho Motivation     F2004          G      B544           5              5 hr

_______________________________________________________________________________
 U- Represents an Undergraduate Class
G- Represents a Graduate Class
 N- # of Students

Report on School Review of Mentoring:
        In the mentoring reports given below students are asked to complete a "Faculty Mentoring
Report" prior to graduating from IUPUI. Students can identifty faculty members at three levels. In the
reports summed over the past 5 years (1997-2001) Dr June was selected as Mentor with the following
frequency:

Total in Associate Professor Rank [1997 to 2002]

Level 1--faculty who have had a remarkable and positive influence on them but are not in their top three
          list (9 times)
Level 2--the top three faculty who have a remarkable and positive influence on them (12 times)
Level 3--the faculty member who have influenced the whole course of their lives and whose effects
          were invaluable (6 times)

Total in Full Professor Rank [2002 Spring to present]

Level 1--faculty who have had a remarkable and positive influence on them but are not in their top three
          list (6 times)
Level 2--the top three faculty who have a remarkable and positive influence on them (3 times)
                                                                                                7

Level 3--the faculty member who have influenced the whole course of their lives and whose effects
          were invaluable (2 times)

Awards Related to Mentoring

  1998, Chancellor’s Bynum P. Mentorship Award, Indiana University-PurdueUniversity.
        This award is presented to a full-time faculty member in the Purdue, IU, or IU Medical
        School by the chancellor of IUPUI for outstanding performance in mentoring of graduate,
        undergraduate, or students in any of the professional schools at the Indianapolis campus

  1998, Psychology Mentorship Award, Indiana University-PurdueUniversity.
        This award is presented to a full-time psychology faculty member in the Purdue School of
        Science at the Indianapolis campus

GRANT SUPPORT:

Extramural

Prior and Present Research Support

   A. “Benzodiazepine Actions on Alcohol Reinforcement”
      Principal Investigator: Harry L. June
      Agency: National Institute of Alcohol Abuse and Alcoholism
      Type: R29 (AA10406-01A2) Period April 1, 1997 – March 30, 2002
      $350,000 direct cost, $520,000 total cost
      The overall goal of this project is to systemically evaluate benzodiazepine receptor ligands
      for their capacity to reduce alcohol-motivated reresponding.

   B. “GABAa Receptor Mechanisms in Alcohol Reinforcement”
      Principal Investigator: Harry L. June
      Agency: National Institute of Alcohol Abuse and Alcoholism
      Type: R21 (AA11555-01A1) Period Sept 1, 1999 – May 30, 2002
      $376, 501 direct cost, $564,000 total cost
      The overall goal of the project is to systematically identify CNS substrates of GABAergic
      transmission in the extended amygdala that regulate EtOH-motivated behaviors.

   C. “GABAa Receptor Subunits Alcohol Reinforcement”
      Principal Investigator: Harry L. June
      Agency: National Institute of Alcohol Abuse and Alcoholism
      Type: R01 (AA12407) Period April 1, 2002 – March 30, 2007
      $875,000 direct cost, $1,158,249 total cost
      The overall goal of the project is to evaluate the alpha 1 and alpha 5 receptor subunits in
      EtOH reinforcement employing 1 and alpha 5 receptor ligands.

   D. “The Alpha-1 GABAA Receptor Regulates Alcohol-Drinking Behaviors”
      Principal Investigator: Harry L. June
      Agency: National Institute of Alcohol Abuse and Alcoholism
      Type: R21 (AA017461) Period April 1, 2008 – April 30, 2010
      $385, 000 direct cost, $1,506,465 total cost
      The overall goal of this project is to employ the RNAi procedure to silence the GABA
      Alpha-1 receptor gene to investigate its effects on alcohol drinking.
                                                                                                    8



   E. “Efficacy of Novel Triple Uptake Inhibitors in Treating Alcoholism and Depression”
      Principal Investigator: Harry L. June
      Agency: National Institute of Alcohol Abuse and Alcoholism
      Type: R01 (AA17461-2) Period December 30, 2008 – Nov 30, 2013
      $1,250,000 direct cost, $1,875,000 total cost
      The overall goal of this project is to systemically evaluate novel triple uptake inhibitors in
      treating alcoholism and depression using alcoholic rats.
      [Active]

   F. “Anxiety and Alcoholism: Novel Benzodiazepine Treatments”
      Principal Investigator: Harry L. June
      Agency: National Institute of Alcohol Abuse and Alcoholism
      Type: R01 (AA017963-01A1) Period September 30, 2009 – August 31, 2011
      $541,000 direct cost, $791,000 total cost
      The initial objective of this proposal is to synthesize novel α1 GABAA subtype-preferring
      ligands for further evaluation of clinical efficacy in treating both excessive alcohol drinking
      (e.g., binge) and the negative affective states (e.g., anxiety, anhedonia) associated with
      abstinence. The secondary objective is to employ molecular biology procedures [e.g., HEK
      cell, siRNA, immunocytochemistry] to determine the "precise" GABAA receptor subtype in
      which the novel α1 ligands inhibit excessive alcohol drinking.
      [Active]

   Pending Grants

   A. GABAA related neuroinflammation regulates binge drinking
      Principal Investigators: Harry L. June and Laure Aurelian
      Agency: National Institute of Alcohol Abuse and Alcoholism
      Type: R01 (AA020080-01) Period August 31, 2010 – July 31, 2015
      1,000,000 direct cost
      The overall goal of this project is to examine the interaction of GABAA receptors and
      neuroimmune factors in regulating binge drinking.
      [Pending review in June 2010]

   B. “GABAA regulated neuroinflammation in alcoholism therapy”
      Principal Investigator: Harry L. June and Laure Aurelian
      Agency: National Institute of Alcohol Abuse and Alcoholism
      Type: RC4 (AA020128-01) Period September 31, 2010 – August 31, 2013
      $1,500,000 direct cost
      The overall goal of this is to examine the interation of GABAA receptors and neuroimmune
      factors in regulating binge and relapse drinking
      [Pending review in July 2010]


Intramural

   A. IUPUI Summer Research Fellowship Grant "Neurobehavioral Determinants of Ethanol
      Reward" (Summer 5/93-8/93) $6,000, Faculty Development Office (Completed)

   B. IUPUI Research Aid Grant "Neurobehavioral Determinants of Ethanol Reward" 5/93-9/93,
      $3,000, Faculty Development Office (Completed)
                                                                                             9



Student Grant/Fellowship Support

   1. †IUPUI Mentorship Grant for Terri Greene "The Novel Benzodiazepine Inverse Agonist
      RO19-4603 decreases EtOH intake in alcohol preferring (P) rats. 9/94-5/95, $1,500
      (Completed)

   2. IUPUI Student Undergraduate Research (SUR) Grant for Scott Duemler, "Interactions
      of RO19-4603 and Ethanol on Tests of Anxiety, Exploration, and Locomotion" 1/94-
      5/94, $1,500, Honors Research Program (Completed)

   3. †IUPUI Mentorship Grant for Samantha Dejaravu "Effects of the Benzodiazepine
      Antagonist, CSG 8216 on Ethanol Intake and the Locomotor Depressant Effects of
      Ethanol" 5/94-8/94, $1,500, Student Research Opportunity Program for Minority
      Students (SROP), Honors Research Program (Completed)

   4. †IUPUI Mentorship Grant for Connease Warren-Reese "Evaluation of novel
      benzodiazepine receptor ligands in high (HAD) and low (LAD) alcohol-preferring rats"
      5/94-8/94, $1,500, Student Research Opportunity Program for Minority Students
      (SROP), Honors Research Program (Completed)

   5. †Short Term Summer Research Fellowship in Biomedical Research for Terri L. Greene,
      "Differential Sensitivity of Benzodiazepine Inverse Agonists in Alcohol-Preferring (P)
      and Non-preferring (NP) Rats" 6/94-8/94, $1,600, IUSM, NIH (Completed)

   6. IUPUI Student Undergraduate Research Award (SUR) IUPUI for John Williams,
      "Interactions of RO19-4603 and Ethanol on Tests of Anxiety, Exploration, and
      Locomotion" 9/94-5/95, $1,500, Honors Research Program (Completed)

   7. †IUPUI Mentorship Grant for Lucas Torres , "Evaluation of Novel Benzodiazepine
      Partial Agonists in Rats With and Without a Predisposition to Alcoholism 9/94-5/96,
      $1,500 (Completed)

   8. †Short Term Summer Research Fellowship in Biomedical Research for Lucas Torres,
      "Evaluation of the anxiolytic properties of novel benzodiazepine receptor ligands in rats
      with a genetic predisposition to alcoholism " 5/95-8/95, $1,600, IUSM, NIH
      (Completed)

   9. IUPUI Student Undergraduate Research (SUR) Grant for Mary Becky Eggers "Effects
      of the Benzodiazepine Antagonist Ethanol Responding " 9/95-5/96, $1,200, Honors
      Research Program (Completed)

   10. IUPUI Mentorship Grant for Dana Zuccarelli, " Effects of Novel Benzodiazepine
       Antagonist on Ethanol Responding" 12/95-5/96, $1,000, Faculty Development Office
       (Completed)

   11. †Short Term Summer Research Fellowship in Biomedical Research for Connease
       Warren- Reese "Characterization of nalmefene, the 6- methylene derivative of
       naltrexone to antagonize ethanol responding in alcohol-preferring rats" 5/96-8/96,
       $1,600, IUSM, NIH (Completed)
                                                                                          10

12. †Short Term Summer Research Fellowship in Biomedical Research for LaFranze Durr,
    "Benzodiazepine with different intrinsic efficacies antagonize ethanol responding in
    alcohol-preferring rats" 5/96-8/96, $1,600, IUSM, NIH (Completed)

13. †IUPUI Mentorship Grant for Anila Ricks-Cord, "Characterization of nalmefene, the 6
    methylene derivative of naltrexone to antagonize ethanol responding in alcohol-
    preferring rats" 5/96-8/96, $1,500, Student Research Opportunity Program for Minority
    Students (SROP), Honors Research Program (Completed)

14. IUPUI Mentorship Grant for Collette Grey, "Novel benzodiazepine antagonists reduce
    responding for reinforcement by ethanol. in alcohol-preferring rats" " 1/98-8/98, $1,000,
    Faculty Development Office (Completed)

15. IUPUI Student Undergraduate Research (SUR) Grant for Pete McKay, "RY 023
    reduces EtOH-maintained responding following injection into the CA1 and CA3
    hippocampal fields." 12/98-5/99, $1,500, Honors Research Program (Completed)

16. †Short Term Research Fellowship in Biomedical Research for Charity Cason, "R0-19-
    4603 reduces EtOH-maintained responding following injection into the Nucleus
    Accumbens." 1/99-5/99, $3,000, IUSM, NIH (Completed)

17. IUPUI Undergraduate Research Opportunity Program (UROP) Grant for Pete McKay,
    "RY 023 reduces EtOH-maintained responding following injection into the CA1 and
    CA3 hippocampal fields." 1/99-5/99, $1,500 (Completed)

18. †Short Term Research Fellowship in Biomedical Research for Katrina Foster, "RY 023
    reduces EtOH-maintained responding following injection into the CA1 and CA3
    hippocampal fields." 1/99-5/99, $3,000, IUSM, NIH (Completed)

19. IUPUI Undergraduate Research Opportunity Program (UROP) for Michelle Carroll,
    "Novel benzodiazepine antagonists infused into the ventral pallidal area reduce
    responding for reinforcement by ethanol. in alcohol-preferring rats" " 12/99-5/00, $1,600
    (Completed)

20. IUPUI Undergraduate Research Opportunity Program (UROP) for William Eiler, "Role
    of the bed nucleus of the stria terminalis in brain stimulation reward in HAD and LAD
    rats" 1/00-5/00, $1,600 (Completed)

21. †Short Term Research Fellowship in Biomedical Research for Dana Milbourn. GABA
    and Opioids Within the Central Amygdala (CeA) Regulate Ethanol-Maintained
    Responding. 5/00-8/00, IUSM, NIH (Completed)

22. †Short Term Research Fellowship in Biomedical Research for Lorie La Duff.
    Responding for Brain Stimulation within the Medial Forebrain Bundle Before and After
    Amphetamine Pretreatment in Alcohol-preferring (P) and Nonalcohol-preferring (NP)
    Rat Lines. 5/00-8/00, IUSM, NIH (Completed)

23. †Short Term Research Fellowship in Biomedical Research for Chaz Mailey. The D1
    Dopamine Receptor Regulate Alcohol-Motivated Behaviors in the Bed Nucleus of the
    Stria Terminalis (BNST) in Alcohol-preferring (P) rats. 5/01-8/01, IUSM, NIH
    (Completed)
                                                                                               11



       24. †Short Term Research Fellowship in Biomedical Research for Lathen Hardy.
           Responding for Brain Stimulation Reward (BSR) in the the Bed Nucleus of the Stria
           Terminalis (BST) in High Alcohol Drinking (HAD) and Low Alcohol Drinking (LAD) Rat
           Lines 5/01-8/01, IUSM, NIH (Completed)

       25. †Short Term Research Fellowship in Biomedical Research for Chaz Mailey. Novel
           Alpha-1 Receptor Ligands Regulate Alcohol-Motivated Behaviors: Comparison with
           Naltrexone 5/02-8/02, IUSM, NIH (Completed)

       26. †Short Term Research Fellowship in Biomedical Research for Lathen Hardy.
           Responding for Brain Stimulation Reward (BSR) in the the Bed Nucleus of the Stria
           Terminalis (BST) in Alcohol-preferring (P) and Nonalcohol-preferring (NP) Rat Lines.
           5/02-8/02, IUSM, NIH (Completed)

       27. †Short Term Research Fellowship in Biomedical Research for Sandra Nobel.
           GABA/DA Interaction in the Bed Nucleus of the Stria Terminalis (BST) Regulate
           Alcohol-Motivated Behaviors. 5/02-8/02, IUSM, NIH (Completed)

       † - Represents student with minority status.

PATENTS HELD:
2002      [January 9th] Provisional Patent: “Methods for Reducing Alcohol Craving in Chronic
          Alcoholics”. Patent proposes to use a1 selective benzodiazepine antagonists to
          reduce alcohol drinking via direct blockade of the reinforcing effects. An additional
          novel feature of the invention is that the a1 agents also reduce the anxiety that
          alcoholics experience upon the withdrawal from alcohol.

PUBLICATIONS:

Peer Reviewed Journal Articles:

       1. June, H.L., & Lewis, M.J. (1989) Ro15-4513 attenuates and enhances open-field
          activity in rats. Alcohol 6, 245-248.

       2. June, H.L., Johnson, L.T., & Lewis, M.J. (1989) Ro15-4513 attenuates depression of
          open-field horizontal activity. Alcohol 6, 335-337.

       3. June, H.L., Hicks, L.H., Lewis, M.J., & Ross, S. (1990) Denatonium saccharide as an
          aversive stimulus in a conditioned taste aversion pardigm. Perceptual and Motor Skills
          71, 1299-1307.

       4. Lewis, M.J., & June, H.L. (1990) Neurobehavioral effects of ethanol on brain stimulation
          reward and spontaneous measures of activity, Alcohol 7, 213-219.

       5. June, H.L., Lummis, G., Colker, R.E., Moore, T.O., & Lewis, M. J. (1991) Ro15-4513
          decreases ethanol consumption in deprived rats. Alcoholism: Clinical and Experimental
          Research 15, 406-411.
                                                                                          12

6. Stitzer, M.L., Wright, C., Bigelow, G.E., June, H.L., & Felch, L.J. (1992) Time course of
   naloxone-precipitated withdrawal after acute methadone exposure in humans. Drug &
   Alcohol Dependence 29, 39-46.

7. June, H.L., June, P.L., Domangue, K.R., Lummis, G. L., & Lewis, M.J. (1992) Failure of
   Ro15-4513 to alter ethanol-induced CTA in rats. Pharmacology, Biochemistry and
   Behavior 41, 455-460.

8. June, H.L., Colker, R.E., Domangue, K.R., Hicks, L.H., June, P.L., & Lewis, M.J. (1992)
   Ethanol self-administration in deprived rats: effects of Ro15-4513 alone, and in
   combination with flumazenil (Ro15-1788). Alcoholism: Clinical and Experimental
   Research 16, 11-16.

9. Moore, T.O., June, H. L., & Lewis, M.J. (1994) Ethanol induced stimulation and
   depression on measures of locomotor activity: effects of basal activity levels in rats.
   Alcohol 10, 537-540.

10. Lewis, M. J., & June, H. L. (1994) Synergistic effects of ethanol and cocaine on brain
    stimulation reward. Journal of Experimental Analysis of Behavior 61, 223-229.

11. June, H. L., Murphy, J.M., Mellor-Burke, J.J., Lumeng, L. & Li, T-K. (1994) The inverse
    benzodiazepine agonist RO19-4603 exerts prolonged and selective suppression of
    ethanol intake in alcohol-preferring (P) rats. Psychopharmacology 115, 325-331.

12. June, H. L., Hughes, R. W., Spurlock, K. R., Domangue, K. R., & Lewis, M. L. (1994)
    Ethanol self-administration in freely-feeding rats: effects of Ro15-4513 alone, and in
    combination with flumazenil (Ro15-1788). Psychopharmacology 115, 332-339.

13. June, H. L., & Lewis, M. J. (1994) Interactions of Ro15-4513 and Ro15-1788
    (Flumazenil) on measures of exploration and locomotion in rats. Psychopharmacology
    116, 309-316.

14. June, H.L., Stitzer, M.L. & Cone, E. (1995). Acute opioid dependence in humans:
    relation to plasma morphine concentration. Clinical Pharmacology and Therapeutics
    57, 270-280.

15. Walsh, S.L., June, H.L., Schuh, K.J., Preston, K.L., Bigelow, G.E., & Stitzer, M.L.
    (1995) Effects of buprenorphine and methadone in methadone-maintained subjects.
    Psychopharmacology 119, 268-277.

16. June, H.L., Lin, M., Greene, T.L., Lewis, M.J., & Murphy, J.M. (1995) Effects of
    negative modulators of GABAergic efficacy on ethanol intake: correlation of
    biochemical changes with pharmacological effect using behavioral paradigm. Journal of
    Experimental and Clinical Psychopharmacology 3, 252-260.

17. June, H.L., Duemler, S., Greene, T.L., Williams, J., Lin, M., Chen, S.H.A., Lewis, M.J. &
    Murphy, J.M. (1995) Effects of RO19-4603 on the maintenance of tolerance to a single
    dose of ethanol. Journal of Pharmacology and Experimental Therapeutics 247, 1105-
    1112.
                                                                                            13

18. June, H.L., Murphy, J.M., Hewitt, R.L., Greene, T.L., Lin, M., Mellor-Burke, J., Lumeng,
    L., & Li, T.-K. (1996) Benzodiazepine receptor ligands with different intrinsic efficacies
    alter ethanol intake in alcohol-nonpreferring (NP) rats. Neuropsychopharmacology 14,
    55-66

19. Greenwald, M., June, H.L., Marco, A., & Stitzer, M.L. (1996) Clinical pharmacology of
    fentanyl in drug abusers. Journal of Pharmacology and Experimental Therapeutics 277,
    1228-1235.

20. June, H.L., Greene, T.L., Murphy, J.M., Lin, M., Williams, J.A, Cason, C.R., Mellor-
    Burke, J.J., Duemler, S. Torres, L., Lumeng, L. & Li, T-.K. (1996) Effects of the
    benzodiazepine inverse agonist RO19-4603 alone, and in combination with the
    benzodiazepine receptor antagonists, flumazenil, ZK 93426, and CGS 8216 on ethanol
    intake in alcohol-preferring (P) rats. Brain Research 734, 19-34.

21. June, H.L., Torres, L., Cason, C.R., Hwang, B.H., Braun, M.R., Murphy, J.M. (1998)
    The novel benzodiazepine inverse agonist RO19-4603 antagonizes ethanol motivated
    behaviors: neuropharmacological studies. Brain Research 784, 256-275.

22. June, H.L., Dejaravu, S.L., Williams, J., Cason, C.R., Eggers, M.W., Greene, T.L.,
    Leviege, T., Torres, L. Braun, M.R., Murphy, J.M. (1998) GABAergic modulation of the
    behavioral actions of ethanol in alcohol-preferring (P) and nonpreferring (NP) rats.
    European Journal of Pharmacology 342, 139-151.

23. June, H.L., Zucarelli, D., Craig, K.S., DeLong, Jana, Cason, C.R., Torres, L., & Murphy,
    J.M. (1998) High affinity benzodiazepine antagonists reduce responding maintained by
    EtOH presentation in ethanol-preferring (P) rats. Journal of Pharmacology and
    Experimental Therapeutics 284, 1006-1014.

24. June, H. L., Cason, C. R., Cheatham, G., Ruiyan L. Gan T., & Cook, J.M. (1998)
    GABAA-benzodiazepine receptors in the striatum are involved in the sedation produced
    by a moderate, but not an intoxicating ethanol dose in outbred Wistar rats. Brain
    Research 794, 103-118.

25. June, H.L., Eggers, M.W., Warren-Reese, C., Ricks, A., & Cason, C.R. (1998) The
    effects of the novel benzodiazepine receptor inverse agonist Ru 34000 on ethanol-
    maintained responding. European Journal of Pharmacology 350, 151-158.

26. June, H. L., Cason, C. R., Chen, S.H.A., & Lewis, M. J. (1998) Dose and time-
    dependent effects of buprenorphine on ethanol self-administration in rat.
    Psychopharmacology 140, 29-37.

27. June, H.L., Grey, C., Warren-Reese, C., Lawrence, A. Thomas, A., Cummings, R.,
    Williams, L., McCane, S.L., Durr, L.F., Mason, D. (1998) The opioid receptor antagonist
    nalmefene reduces alcohol-motivated behaviors: preclinical studies in alcohol
    preferring (P) and outbred Wistar rats. Alcoholism: Clinical and Experimental Research
    22, 2174-2185.

28. June, H.L., McCane, S., Zink, R.W., Portoghese, P., Li, T.-K. & Froehlich, J.C. (1999)
    The                                                             -motivated behaviors.
    Psychopharmacology 147, 81-89.
                                                                                          14



29. June, H.L., Harvey, S.C., Foster, K.L., McKay, P.F., Cummings, R., Garcia M., Mason,
    D., Grey, C., McCane, S.L Williams, L., Durr, L.F., Johnson, T.B., Xiaohui, He, Rock,
    S., & Cook, J.M (2001) GABAA-
    hippocampal fields regulate ethanol-motivated behaviors: An extended ethanol reward
    circuitry. Journal of Neuroscience 21, 2166-2177.

30. Harvey S.C., Foster K.L., McKay P.F., Carroll Mm, Seyoum R., Woods J.E. II, Grey C.,
    McCane S.,Cummings R., Mason D., Jones C.M., Ma C., Cook J.M., & June H.L.
    (2002) The GABAA                                                            -seeking
    behaviors. Journal of Neuroscience 22, 3766-3775.

31. Eiler II, W.J.A., Seyoum, R., Foster, K.L., Mailey, C, and & June, H.L. (2003) The D1
    dopamine receptor regulates alcohol-motivated behaviors in the bed nucleus of the
    stria terminalis in Alcohol-Preferring (P) rats. Synapse 48, 45-56.

32. Woods, J.E. II, McKay, P.F. Seyoum, R., Chen, A., Masters, J., La Duff, L., Lewis, M.J.,
    & June, H.L. (2003) Differential Responding for brain-stimulation reward and sucrose in
    High Alcohol Drinking (HAD) and Low Alcohol Drinking (LAD) Rats. Alcoholism: Clinical
    and Experimental Research 27, 926-936.

33. June, H.L., Foster, K.L., McKay, P.F., Carroll, M.R., Seyoum, R., Woods, J.E., Harvey,
    S.C., Eiler, W.J.A. II, Grey, C., McCane, S., Garcia, M., Jones, C.M., Mason, D.,
    Cummings, R., Yin, W., Cook, J.M., & Skolnick, P. (2003) The reinforcing properties of
    alcohol are mediated by GABA(A1) receptors in the ventral pallidum.
    Neuropsychopharmacology 28, 2124-2137.

34. June, H.L, Cummings, R., Eiler, W.J.A. II, Foster, K.L., Garcia, M., Mason, D., McKay,
    P.F., Hawkins, S., & Mason, M. (2004) Central opioid receptors differentially regulate
    the nalmefene-induced suppression of ethanol- and saccharin-reinforced behaviors in
    alcohol-preferring (P) rats. Neuropsychopharmacology 29, 285-299.

35. McKay P.F., Foster K.L., Mason D., Cummings R., Garcia M., Williams. L., Eiler, W.J.A.
    II, Woods J.E., Harvey S.C., Garcia M., Grey C., Grey C., Mc Cane S., Xiaohui H.,
    Cook, J.M., & June H.L. (2004) A high affinity ligand for GABAA-receptor containing
    alpha5 subunit antagonizes ethanol's neurobehavioral effects in Long-Evans rats.
    Psychopharmacology 172, 455-462.

36. Foster K.L., McKay P.F., Seyoum R., Milbourne D., Yin W., Cook J.M., June H.L.
    (2004) GABA(A) and opioid receptors of the central nucleus of the amygdala selectively
    regulate ethanol-reinforced behaviors. Neuropsychopharmacology 29, 269-284.

37. Eiler II, W.J.A., Woods II, J.E., Masters, J., McKay, P.F., Hardy III, L., Goergen, J.J.,
    Mensah-Zoe, B., Cook, J.B., Johnson, N.J., & June, H.L. (in press) Brain stimulation
    reward performance and sucrose maintained behaviors in alcohol preferring (P) and
    non-preferring (NP) rats. Alcoholism: Clinical and Experimental Research

38. Cook J.B., Foster K.L., McKay P.F., Harvey S.C., Carroll Mm, Seyoum R., Woods J.E.
    II, Grey C., McCane S.,Cummings R., Mason D., Jones C.M., Ma C., Cook J.M., &
    June H.L. (2005) Further studies of the GABAA receptor
    EtOH-seeking behaviors. Alcoholism: Clinical and Experimental Research 9, 1390-401.
                                                                                           15



39. Eiler II, W.J.A., Masters, J., McKay, P.F., Hardy III, L., Goergen, J.J., Mensah-Zoe, B.,
    Seyoum, R., Cook, J.B., Johnson, N.J., Neal-Beliveau, B., & June, H.L. (2006)
    Amphetamine lowers brain stimulation reward (BSR) threshold in alcohol preferring (P)
    and non-preferring (NP) rats: regulation by D1 and D2 receptors in the nucleus
    accumbens. Experimental and Clinical Psychopharmacology 14, 361-76.

40. Chester, J.A., Rausch, E.J., June, H.L., & Froehlich J.C. (2006) Decreased reward
    during acute alcohol withdrawal in rats selectively bred for low alcohol drinking.
    Alcohol. 38, 165-72.

41. Eiler II, W.J.A., & June, H.L. (2007) Blockade of GABA(A) receptors within the
    extended amygdala attenuates D(2) regulation of alcohol-motivated behaviors in the
    ventral tegmental area of alcohol-preferring (P) rats. Neuropharmacology. 52, 1570-9.

42. June, H.L. Sr, Foster, K.L., Eiler II, W.J.A., Goergen, J., Cook, J.B., Johnson, N.,
    Mensah-Zoe, B., Simmons, J.O., June, H.L. Jr, Yin, W., Cook, J.M., & Homanics, G.E.
    (2007) Dopamine and benzodiazepine-dependent mechanisms regulate the EtOH-
    enhanced locomotor stimulation in the GABAA alpha1 subunit null mutant mice.
    Neuropsychopharmacology. 32, 137-52.

43. Eiler II W.J.A., Hardy, L., Woods, J., Seyoum, R., & June, H.L. (2007) Responding for
    Brain Stimulation Reward (BSR) in the Bed Nucleus of the Stria Terminalis (BST) in
    Alcohol Preferring (P) Rats Following EtOH and Amphetamine Pretreatments.
    Synapse. 61, 912-24.

44. June H.L., Tzeng Yang A.R., Bryant J.L., Jones O., Royal W 3rd. (2009) Vitamin A
    deficiency and behavioral and motor deficits in the human immunodeficiency virus type
    1 transgenic rat. Journal of Neurovirology. 15(5-6):380-9.

45. Yang A.R., Yi H.S., Mamczarz J., June H.L. Jr., Hwang B.H., June H.L. Sr. (2009)
    Deficits in substance P mRNA levels in the CeA are inversely associated with alcohol-
    motivated responding. Synapse. 63, 972-81.

46. Wiltgen B.J., Godsil B.P., Peng Z., Saab F., June H.L., Linn M.L., Cook J.M., Houser
    C.R., O'Dell T.J., Homanics G.E., Fanselow M.S. (2009) The alpha1 subunit of the
    GABA(A) receptor modulates fear learning and plasticity in the lateral amygdala.
    Frontiers in Behavioral Neuroscience. 3:37.

47. Yang, A.R.S.T., Mamczarz, J., Yi, H.S., Mallick, N., Krieter, P.A., Skolnick, P., Basile,
    A.S., June, H.L. (in press) Evaluation of DOV 102,677, the Triple Monoamine Uptake
    Inhibitor on Alcohol-Motivated Responding and a Rat Model of Antidepressant Activity
    in Alcohol-Preferring (P) Rats. Alcoholism: Clinical and Experimental Research.

48. Eiler II, W.J.A., Cook, J.B., Johnson, N., Mensah-Zoe, B., June, H.L. Jr, Homanics
    G.E., June H.L. Sr. (Submitted) Differential responses elicited by EtOH and BDZ
    treatments alone, and the combination of the two on motor-performance measures in
    GABA alpha1 subunit null mutant and wild-type mice. Alcoholism: Clinical and
    Experimental Research
                                                                                                16

      49. Lui, J., Yang, A.R.S.T., Kelly, T., Puche, A.C., Elnabawi, A., Merchenthaler, I., Esoga,
          C., Sieghart, W., June H.L., Aurelian, L. (Submitted) GABAA α2-regulated innate
          immunity and neuroinflammation in the central amygdala: key players in binge alcohol
          drinking? Journal of Neuroscience


Book Chapters:

      June, H.L., (2002) “Alcohol Initiation Procedures in Rats: Methods Used in Evaluating
            Potential Pharmacotherapeutic Agents,” In Current Protocols in Neuroscience
            (Edited by Crawley, J., Gerfen, C., McKay, R., Rogawski, M., Sibley, D., & Skolnick,
            P.). John Wiley and Sons, NY, NY, 9:1-23

      June, H.L., & Eiler II, W.J.A. (2007). “Dopaminergic and Gabaergic Regulation of Alcohol-
             Motivated Behaviors: Novel Neuroanatomical Substrates,” In Handbook of
             Contemporary Neuropharmacology ([Editor-in-Chief: Sibley, D.] [Associate Editors:
             Hanin, I., Kuhar, M., & Skolnick, P.]) John Wiley and Sons, NY, NY, 2:1-72.

      June H.L., Gilpin N.W. (2010). “Operant self-administration models for testing the
            neuropharmacological basis of ethanol consumption in rats.” In Current Protocols in
            Neuroscience. John Wiley and Sons, NY, NY 9: 9.12.1-26.

Abstracts:

      June, H.L., & Lewis, M.J. (1986). Pre-exposure Effects of a Self-Administered Drug on a
             Non-Self-Administered Unconditioned Stimulus. Society for Neuroscience
             Abstracts, Vol. 12, Part 1.

      Johnson, L.T., June, H.L., & Lewis, M.J. (1987). The effects of Ro15-4513 on generalized
            motor activity. Society for Neuroscience Abstracts, Vol. 13, Part

      June, H.L., Andrade, J.R., & Lewis, M.J. (1987). Effects of feeding schedule: investigation
             of morphine-induced feeding. Society for Neuroscience Abstracts, Vol. 13, Part 1.

      June, H.L., Moore, T.O., Edwards, K.L., & Lewis, M.J. (1988). Differential ethanol and
            habituation effects on open-field activity measures. Society for Neuroscience
            Abstracts Vol. 14, Part 2.

      June, H.L., Hicks, L., Lawson, W.B., & Lewis, M.J. (1988). A comparison of the effects of
             clozapine and haloperidol on drinking behavior in the rat. Proceedings and
             Abstracts of the Annual Meeting of the Eastern Psychological Association, Vol. 59,
             p. 46.

      June, H.L., Lewis, M.J., Ross, S., Colker, R.E., & Hicks, L.H. (1988). A comparison of the
             effects of clozapine on a cocaine versus a CuSO4-induced conditioned taste
             aversion in the rat. Proceedings and Abstracts of the Annual Meeting of the Eastern
             Psychological Association, Vol. 59, p. 49.

      Lewis, M.J., Bixler, M. A., & June, H.L. (1988). Similar behavioral effects of benzodiazepine
             inverse agonists. Alcoholism: Clinical and Experimental Research, Vol.. 12, p. 315.
                                                                                           17

Siegert, F.G., June, H.L., Petty, R.M., & Colker, R.E. (1989). The effects of external
       rewards and teaching styles on the motor performance of mentally retarded
       students. Proceedings and Abstracts of the Annual Meeting of the Eastern
       Psychological Association, Vol. 59, p. 37.

June, H.L., Hicks, L.H., Lewis, M.J. & Ross, S. (1989). Denatonium saccharide as an
      aversive stimulus in a conditioned taste aversion paradigm. Proceedings and
      Abstracts of the Annual Meeting of the Eastern Psychological Association, Vol. 60,
      p. 50.

Moore, T.O., June, H.L., & Lewis, M.J. (1990). Ro15-4513 antagonizes ethanol-induced
      stimulant effects on measures of exploration in rats. Society for Neuroscience
      Abstracts Vol. 16, Part 1, p. 435, 1990.

Hicks, L.H., June, H.L., Moore, T.O., & Lewis, M.J. (1990). A comparison of three inverse
       benzodiazepine agonists on ethanol stimulant effects. Society for Neuroscience
       Abstracts Vol. 16, Part 1, p. 756, 1990.

June, H.L., Domangue, K.R., Hughes, R.W., Spurlock, H.L., & Lewis, M.J. (1991).
      Differential effects of dopamine and serotonin antagonists on ethanol self-
      administration. Poster presented at the Research Society on Alcoholism Annual
      Meeting, Marco Island, Florida, June.

June, H.L., Stitzer, M.L., & Liebson, I.A (1991). Antagonist sensitivity time course in
      humans: effects of morphine-naloxone interval. National Institute of Drug Abuse,
      Research Monograph, ed. L.S. Harris. No. 92, In Committee on Problems of Drug
      Dependence U.S. Government Printing Office, Washington, D.C.

Domangue, K.R., June, H.L., Smith, T.D., Dixon, J.T., Norona, A., & Lewis, M.J. (1991).
     Buprenorphine produces biphasic effects on ethanol self-administration. Society for
     Neuroscience Abstracts Vol. 17, Part 2, p. 1422.

June, H.L., & Lewis, M.J. (1991). Ro15-4513 effects on ethanol-induced locomotor activity
       in alcohol-preferring and non-preferring rats. Society for Neuroscience Abstracts
       Vol. 17, Part 2, p. 1425.

Hughes, R.W., June, H.L., Spurlock, H.L., Dixon, J.T., Hicks, L.H., & Lewis, M.J. (1991)
      Effects of cocaethylene on oral ethanol self-administration. Society for
      Neuroscience Abstracts Vol. 17, Part 2, p. 1423

Bixler, M. A., June, H.L., & Lewis, M.J. (1991). Effects of oral ethanol self-administration
        and Ro15-4513 on wheel running behavior. Society for Neuroscience Abstracts Vol.
        17, Part 2, p. 1423.

Lewis, M.J., & June, H.L. (1991). Buprenorphine produces biphasic effects on ethanol self-
       administration. M.J. Lewis and H.L. June. Poster presented at the American
       College of Neuropsychopharmacology, San Juan, Puerto Rico, December.

June, H.L., & Lewis, M.J. (1991). Effects of cocaethylene on oral ethanol self-
      administration. Poster   presented    at    the    American College   of
      Neuropsychopharmacology, San Juan, Puerto Rico, December.
                                                                                            18



June, H.L., Preston, K.L., Bigelow, G.E., & Stitzer, M.L. (1992). Effects of buprenorphine
       and methadone in methadone-maintained subjects. National Institute of Drug
       Abuse, Research Monograph, ed. L.S. Harris. No. 93, In Committee on Problems of
       Drug Dependence U.S. Government Printing Office, Washington, D.C.

Lewis, M.J., Smith, T., Domangue, K., Bryant, J., & June, H.L. (1992). Locomotor
       stimulation by oral alcohol self-administration in alcohol preferring (P) rats: blockade
       by dopamine (DA) and 5-HT3 receptor antagonists. Paper presented at the
       American College of Neuropsychopharmacology Annual Meeting, San Juan, Puerto
       Rico, December.

June, H.L., Preston, K.L., Marco, A., & Stitzer, M.L (1992). Acute opioid dependence after
       a single fentanyl exposure in humans. Paper presented at the American College of
       Neuropsychopharmacology Annual Meeting, San Juan, Puerto Rico, December.

Starasto, A.R., Blakley, G.G., June, H.L., & Lewis, M.J. (1994). The benzodiazepine RO16-
       6028 (bretazenil) augments the depressants effects of ethanol. Society for
       Neuroscience Abstracts Vol. 20, p. 1606

Williams, J., June, H.L., Dejaravu, S., & Murphy, J.M. (1994). The benzodiazepine
       antagonist CGS-8216 exerts prolonged and selective attenuation of ethanol intake
       in alcohol-preferring (P) rats. Society for Neuroscience Abstracts Vol. 20, p. 1606

Duemler, S., June, H.L., Williams, J., Breen, T.E., Lewis, M.J., & Murphy, J.M. (1994). The
      benzodiazepine receptor inverse agonist RO19-4603 exerts prolonged antagonism
      of the locomotor depressant effects of ethanol in alcohol-preferring (P) rats. Society
      for Neuroscience Abstracts Vol. 20, p. 1606

June, H.L., Greene, T.L., Lin, M., & Murphy, J.M. (1994). Differential sensitivity of the
      benzodiazepine inverse agonist RO19-4603 on the locomotor depressant effects of
      ethanol in alcohol-preferring (P) and -nonpreferring (NP) rats. Society for
      Neuroscience Abstracts Vol. 20, p. 499

Hewitt, R.L., June, H.L., Murphy, J.M., Greene, T.L., Lin, M., Mellor-Burke, J.J., Lumeng,
        L., & Li, T.-K. (1994). Does tolerance develop to the ethanol suppressant effects of
        the benzodiazepine receptor inverse agonist, RO19-4603? Alcoholism: Clinical and
        Experimental Research, Vol. 18, p. 487.

June, H.L., Murphy, J.M., Hewitt, R.L., Greene, T.L., Lin, M., Chen, S.H.A., Mellor-Burke,
       J.J., Lumeng, L., & Li, T.-K. (1994). Benzodiazepine receptor ligands with different
       intrinsic efficacies alter ethanol intake in alcohol non-preferring (NP) rats.
       Alcoholism: Clinical and Experimental Research, Vol. 18, p. 487.

June, H.L., Chen, S.H.A., Duemler, S., Lin, M. Greene, T.L., Williams, J., Hewitt, R.L.,
      Mellor-Burke, J.J., Lewis, M.J. & Murphy, J.M. (1994). Effects of RO19-4603 on the
      maintenance of tolerance to a single dose of ethanol. Alcoholism: Clinical and
      Experimental Research, Vol. 18, p. 609.

June, H.L., Murphy, J.M., Lewis, M.J., Lumeng, L., Li, T-K. (1994). Differential sensitivity of
       the benzodiazepine inverse agonist RO19-4603 on the locomotor depressant
                                                                                            19

       effects of ethanol in low and high drinking F2 rats. Paper presented at the American
       College of Neuropsychopharmacology, San Juan, Puerto Rico, December.

June, H.L., Lewis, M.J., Murphy, J.M., Lumeng, L., Li, T-K. (1994). The benzodiazepine
       antagonists CGS-8216 and ZK 93426 attenuate ethanol intake in alcohol-preferring
       (P) rats. Paper presented at the American College of Neuropsychopharmacology,
       San Juan, Puerto Rico, December.

June, H.L., Williams, J.A., Cason, C.R., Braun, M., Torres, L. Allen, Murphy, J.M., Lumeng,
       L., Li, T-K (1995). Bretazenil exerts anxiolytic effects in alcohol-preferring (P) rats.
       Alcoholism: Clinical and Experimental, Vol. 19, p.74

June, H.L., Williams, J.A., Cason, C.R., Devaraju, M., Lin, M. Murphy, J.M., Lumeng, L., Li,
       T-K (1995). Low doses of gamma-hydroxybutyric acid (GHB) attenuate ethanol
       intake in alcohol-preferring (P) rats. Alcoholism: Clinical and Experimental, Vol. 19,
       p.52

June, H.L., Murphy, J.M., Lewis, M.J. Lumeng, L. & Li, T-K. (1995). The inverse agonist
       RO19-4603 antagonizes EtOH intake and EtOH reinforced responding in alcohol-
       preferring (P) rats. Paper presented at the American College of
       Neuropsychopharmacology, San Juan, Puerto Rico, December.

Zuccarelli, D., June, H.L., Durr, L.F., & Murphy, J.M. (1996) Benzodiazepine receptor
      ligands with different intrinsic efficacies modulate EtOH-reinforced responding in
      alcohol-preferring (P) rats. Alcoholism: Clinical and Experimental Research.
      20:12A-#50

Craig, K., June, H.L., Torres, L. Braun, M.R. & Murphy, J.M. (1996) Benzodiazepine
       receptor antagonists modulate the behavioral actions of ethanol. Alcoholism:
       Clinical and Experimental Research 20:12A-#49

Eggers, M.W., June, H.L., Ricks, A., Cason, C.R., & Murphy, J.M. (1996). The novel
      benzodiazepine inverse agonist RU 34000 and antagonist RU 40410 antagonizes
      EtOH-reinforced responding: in alcohol-preferring (P) rats. Alcoholism:Clinical and
      Experimental Research 20:12A-#52

Cason, C.R., June, H.L., Matecka, D. & Murphy, J.M. (1996). Effects of the selective, high
      affinity ligand ZG-63 for diazepam insensitive subtype of the benzodiazepine
      receptor on EtOH-reinforced responding. Alcoholism: Clinical and Experimental
      Research. 20:12A-#51

June, H.L., Murphy, J.M., Lewis, M.J., Froehlich, J., & Lumeng, L. (1996) Preclinical
      characterization of the 6-methylene derivative nalmefene in alcohol-preferring rats.
      Paper presented at the annual meeting of the American College of
      Neuropsychopharmacology, San Juan, Puerto Rico, Dec. 1996.

June, H.L., Murphy, J.M., Lewis, M.J., & Lumeng, L. (1996) GABAergic transmission in the
       mesoaccumbens is involved in alcohol-self administration in alcohol-preferring rats.
       Paper presented at the annual meeting of the American College of
       Neuropsychopharmacology, San Juan, Puerto Rico, Dec. 1996.
                                                                                       20

June, H.L., Hwang, B.H., & Murphy, J.M. (1997) GABAergic transmission in the meso-
      accumbens is involved in alcohol motivated behaviors in alcohol-preferring (P) and
      outbred Wistar rats. Paper presented at the Annual European Society for
      Biomedical Research on Alcoholism in a symposium entitled "Neurobiology of
      alcohol reinforcement", sponsored by the 6th Congress and Karolinska Institute,
      Stockholm, Sweden, June 28-July 1, 1997. Alcohol and Alcoholism 32:337.

Cason, C.R., June, H.L., Fredericks M., Cheatham, G., Chen, A., Cook, J., Gan, T., &
      Murphy, J.M. (1997) GABAergic regulation of the reinforcing properties of alcohol in
      Wistar rats. Society for Neuroscience Abstracts Vol. 23, p. 959

June, H.L., Cheatham, G., Fredericks M., Cason, C.R., Chen, A., Cook, J., Gan, T., &
      Murphy, J.M. (1997) GABAergic regulation of the sedative properties of alcohol in
      the striatum of Wistar rats. Society for Neuroscience Abstracts Vol. 23, p. 958

Lewis, M.J., Starosta A.N., & June, H.L. Bretazenil (RO16-6028) blocks ethanol induced-
       activation, but does not potentiate the depressant effects of alcohol. American
       College Neuropsychopharmacology, Kona, Hawaii, Dec. 1997.

June, H.L., Cheatham, G., Fredericks M., Cason, C.R., Chen, A., Cook, J., Gan, T., &
      Murphy, J.M. (1997) GABAA-benzodiazepine receptors in the striatum are involved
      in the sedation produced by a moderate, but not an intoxicating ethanol dose in
      wistar rats. American College of Neuropsychopharmacology, Kona, Hawaii, Dec.
      1997.

June, H.L., McCane, S.L., Williams, L., Grey, C., Rock, S., & Johnson, T.B. (1998)
      Microinjections of nalmefene, the 6-methylene derivative of naltrexone in the
      nucleus accumbens and ventral tegmental area reduces responding maintained by
      ethanol. Behavioral Pharmacology 9:S48


June, H., Grey, C., Johnson, T.B., Williams, L., McKay, P., Rock, S., He, X., & Cook, J.M.
       (1998). GABAergic substrates in the nucleus accumbens and dorsal hippocampus
       mediate responding maintained by EtOH presentation in alcohol-preferring (P) rats.
       Behavioural Pharmacology 9:S47

McCane, S.L. Rock, S., Williams, L., Grey, C., Johnson, T.B. & June, H.L. (1998)
     Microinjections of nalmefene, the 6-methylene derivative of naltrexone in the
     nucleus accumbens and ventral tegmental area reduces responding maintained by
     ethanol. Alcohol Clin Exp Res 22:45A [Abstract # 250]

June H.L., McCane S.L., Zink, R.W., Portoghese, P.S., Li, T.-K., & Froehlich, J.C. (1998).
      Opioid receptor antagonists reduce responding for ethanol. Alcohol Clin Exp Res
      22:45A [Abstract # 248]


       specific benzodiazepine (BDZ) ligand reduces responding maintained by ethanol
       under different schedules of availability. Alcohol Clin Exp Res 22:11A [Abstract #
       45]
                                                                                           21


                                                                                             A
       receptor subunit in alcohol- preferring (P) and nonpreferring (NP) rats. Alcohol Clin
       Exp Res 22:11A [Abstract # 44].

June, H.L., McKay, P.F., Grey, C., Melendez, R.L., Foster, F., Johnson, T.B., He, X. &
       Cook, J.M (1998). RY 023: A High-Affinity, Selective Ligand for GABAA-Receptor
                      -Subunits Attenuates Responding Maintained by Ethanol Following
       Microinjection Into the CA1 Hippocampal Area. (1998). Paper presented at the
       American College of Neuropsychopharmacology, Las Crobas, Puerto Rico,
       December.

Foster, K.L., McKay, P.F., Mason, D., Cummings, R., Garcia, M., He, X. Cook, J.M. &
       June, H.L (1999). RY 023: A Selective GABAA- -Subunit Ligand Attenuates
       Responding Maintained by Ethanol Following Microinjection Into the CA1 and CA3
       Hippocampal Areas. Alcohol Clin Exp Res 22:16A [Abstract # 38].

Cummings, R., Garcia, M., Mason, D., McKay, P.F., Foster, K.L., & June, H.L (1999).
     Differential Effects of Unilateral Versus Bilateral Microinjections of Nalmefene in the
     Nucleus Accumbens and Ventral Tegmental Area in Alcohol Preferring (P) Rats.
     Alcohol Clin Exp Res 22:16A [Abstract # 62].

McKay, P.F., Mason, D., Cummings, R., Garcia, M., Foster, K.L., He, X. Cook, J.M. &
      June, H.L (1999). The GABAA- -Subunit Mediate the Sedative and Rewarding
      Effects of Ethanol: Preclinical Studies in Outbred Rats. Alcohol Clin Exp Res
      23:12A [Abstract # 39].

June, H.L., McKay, P.F., Foster, K.L., Mason, D., Cummings, R., Garcia, M., He, X. &
      Cook, J.M (1999). The               A-Receptor Subunit in the CA1 and CA3
      Hippocamus Regulate Alcohol Responding in “P” Rats. Alcohol and Alcoholism
      34:425 [Abstract # 18].

Carroll, M., Foster, K.L., Harvey, S., McKay, P.F., Cook, J.M., & June, H.L. (2000).
        Selective GABAA-             it ligands (e.g., ßCCt, 3-PBC) attenuate responding
        maintained by ethanol following microinjection into the ventral pallidum. Alcohol Clin
        Exp Res Alcohol Clin Exp Res 24:53A [Abstract # 242].

Foster, K.L., McKay, P.F., Harvey, S., Cook, J.M., & June, H.L. (2000). GABAergic in the
       central amygdaloid nucleus regulate alcohol motivated behaviors in alcohol-
       preferring (P) Alcohol Responding in “P” Rats. Alcohol and Alcoholism 24:47A
       [Abstract # 241].

Woods, J., McKay, P.F., Lewis, M. J., & June, H. L. (2000). Basal brain stimulation reward
      (BSR) performance in high alcohol drinking (HAD) and low alcohol drinking (LAD)
      rat lines. Alcohol Clin Exp Res 24:53A [Abstract # 280].

Yin W., Carroll M., June H.L., & Cook, J.M., (2001). Alcohol’s euphoric properties are
      regulated by the GABAA-
      Problem and Drug Dependence annual meeting in June 2001.
                                                                                        22

Lewis, M. J., & June, H. L. (2001). Basal brain stimulation reward (BSR) in alcohol-
       preferring (P, HAD) and non-preferring (NP, LAD) rat lines. Paper presented at the
       American College of Neuropsychopharmacology, Waikoloa, Hawaii, Dec. 2001.

Woods, J., II, Seyoum R., McKay, P.F., Foster, K.L., & June, H.L. (2001). Differential
      responding for brain stimulation reward (BSR) and sucrose-maintained responding
      in alcohol preferring (P) and non-preferring (NP) rats. Paper to be presented at the
      annual meeting of the Research Society on Alcoholism in Montreal, Canada, June,
      2001.

Woods, J., II, Seyoum R., McKay, P.F., Foster, K.L., & June, H.L. (2001) Brain stimulation
      reward (BSR) performance in high alcohol drinking (HAD) and low alcohol drinking
      (LAD) rat lines: Effects of dopamine (DA), opioid, and benzodiazepine (BDZ)
      antagonist pretreatments. Paper to be presented at the annual meeting of the
      Research Society on Alcoholism in Montreal, Canada, June, 2001.

Foster, K.L., Seyoum R, McKay, P.F.,Cook, J.M., & June, H.L. (2001) GABA and opioid
       receptors in the in the central amygdaloid nucleus regulate alcohol and sucrose
       motivated behaviors. Paper to be presented at the annual meeting of the Research
       Society on Alcoholism in Montreal, Canada, June, 2001.

Carroll, M.R., Woods, J., Seyoum, R.A., Cook, J.M., & June, H.L. (2001) The role of the
        GABAA                                                                   perties of
        benzodiazepines in high and low alcohol drinking rats. Paper to be presented at the
        annual meeting of the Research Society on Alcoholism in Montreal, Canada, June,
        2001.

Hardy, L., Eiler II, W.J.A., Woods, J., Seyoum, R. & June, H.L. (2002) Responding for Brain
       Stimulation Reward (BSR) in the Bed Nucleus of the Stria Terminalis (BST) in High
       Alcohol Drinking (HAD) and Low Alcohol Drinking (LAD) Rat Lines. Paper
       presented at the annual meeting of the Research Society on Alcoholism in San
       Francisco, CA, June, 2002

Goergen, J., Seyoum, R.& June, H.L. (2002) Dopamine, But Not GABAA Receptors of the
      Lateral Hypothalamus (LH) Regulate Alcohol-Maintained Responding. Paper
      presented at the annual meeting of the Research Society on Alcoholism in San
      Francisco, CA, June, 2002

Woods, J.E., Mc Kay, P.F. & June, H.L. (2002). Responding for Brain Stimulation within the
      Ventral Tegmental Area Before and After Amphetamine Pretreatment in High
      Alcohol Drinking (HAD) and Low Alcohol Drinking (LAD) Rat Lines. Paper
      presented at the annual meeting of the Research Society on Alcoholism in San
      Francisco, CA, June, 2002

Eiler II, W.J.A., Mailey, C., & June, H.L. (2002). The D1 Dopamine Receptor Regulate
         Alcohol-Motivated Behaviors in the Bed Nucleus of the Stria Terminalis (BNST) in
         Alcohol-preferring (P) rats. Paper presented at the annual meeting of the Research
         Society on Alcoholism in San Francisco, CA, June, 2002.

Foster, K.L., Seyoum, R., Goergen, J., Mensah, B. & June, H.L. (2002). GABA/Dopamine
       Interaction in the Central Amygdala (CeA) Regulate Ethanol-Maintained
                                                                                            23

       Responding. Paper presented at the annual meeting of the Research Society on
       Alcoholism in San Francisco, CA, June, 2002.

Woods, J.E., Mc Kay, P.F. & June, H.L. (2002). Responding for Brain Stimulation within the
      Ventral Tegmental Area Before and After Amphetamine Pretreatment in High
      Alcohol Drinking (HAD) and Low Alcohol Drinking (LAD) Rat Lines. Paper
      presented at the annual meeting of the Society for Neurosciences, Orlando, FL
      November, 2002.

Eiler II, W.J.A., Mailey, C., & June, H.L. (2002). The D1 Dopamine Receptor Regulate
         Alcohol-Motivated Behaviors in the Bed Nucleus of the Stria Terminalis (BNST) in
         Alcohol-preferring (P) rats. Paper presented at the annual meeting of the Society for
         Neurosciences, Orlando, FL November, 2002.

Foster, K.L., Seyoum, R., Goergen, J., Mensah-Zoe, B. & June, H.L. (2002).
       GABA/Dopamine Interaction in the Central Amygdala (CeA) Regulate Ethanol-
       Maintained Responding. Paper presented at the annual meeting of the Society for
       Neurosciences, Orlando, FL November, 2002.

Hardy III L., Eiler II, W.J.A, Masters, J., Woods III, J.E, & June H.L. (2003). Responding for
       brain stimulation reward (BSR) in high alcohol drinking (HAD) and low alcohol
       (LAD) drinking rats following amphetamine and morphine pretreatments. Alcohol
       Clin Exp Res 27:92A [Abstract # 517].

Goergen, J., Mensa-Zoe, B., June, H.L. (2003) The D2 dopamine receptor regulates
      ethanol-motivated behaviors in the lateral hypothalamus of alcohol-preferring (P)
      rats.Alcohol Clin Exp Res 27:92A [Abstract # 519].

Foster, K.L., Goergen, J., Simmons, J., Cook, J.B., Homanics, G., Ferguson, C., June, H.L.
                                                        A receptor subunits in ingestive
        behaviors. Alcohol Clin Exp Res 27:85A [Abstract # 475].

Eiler II, W.J.A., Masters, J., Hardy III, L., Cook, J.B., Woods III, J.E., June, H.L., (2003)
         Alcohol preference predicts amphetamine abuse liability using the brain stimulation
         reward (BSR) paradigm. Alcohol Clin Exp Res 27:91A [Abstract # 516].

Eiler II, W.J.A., Cook, J.B., Masters, J., Woods II, J.E., Goergen, J., Hardy III, L., Johnson,
         N., June, H.L. (2004) Brain stimulation reward performance and sucrose maintained
         behaviors in alcohol preferring (P) and non-preferring (NP) rats. Paper presented at
         the annual meeting of the Research Society on Alcoholism

Cook, J.B., Goergen, J., Mensah-Zoe, B., Eiler II, W.J.A., Hardy III, L., Johnson, N., June,
       H.L. (2004) Dopamine D2 and opioid receptors in the lateral hypothalamus regulate
       ethanol-motivated behaviors in the alcohol-preferring rat. Paper presented at the
       annual meeting of the Research Society on Alcoholism

Liu, J., Yang, A.R.S.T., Yi, H.S., Puche, A.C., Sieghart, W., June, H.L., Aurelian, L.. (2008)
         Excessive alcohol intake is abolished by HSV amplicon delivered GABAA α1 siRNA
         to the ventral pallidum. Presented at the College of Neuropsychopharmacology
         Dept in Scottsdale, AZ
                                                                                              24

MAJOR INVITED SPEECHES:

     Lewis, M.J., Bixler, M.A., June, H.L., Johnson, L.T., & Salmoiraghi, G.C. (1987). Effects of
            Ro15-4513 and ethanol on measures of spontaneous activity. Paper presented at
            the American College of Neuropsychopharmacology, San Juan, Puerto Rico,
            December.

     Lewis, M.J., & June, H.L. (1988) Ro15-4513 potentiation of ethanol-induced stimulation of
            activity. Paper presented at the Fourth Congress of the International Society:
            Biomedical Research on Alcoholism, Kyoto, Japan, July.

     Dockett, K.H., Milburn, N., June, H.L., & Booth, J.E. (1989). Dispelling the myths of
            homeless people in Washington, DC. Roundtable discussion conducted at the
            Annual Southeastern Psychological Association, DC Hilton Hotel, Washington, DC,
            April.

     Lewis, M.J., June, H.L., Perry, L.B., Garnette, M., & Porrino, L.J. (1990). Alteration in
            specific brain activity with stimulant effects of ethanol. Paper presented at the
            Research Society on Alcoholism Annual Meeting, Toronto, Canada, June.

     June, H.L., Perry, L.B., Domangue, K.R., & Lewis, M.J. (1990). Ro15-4513 attenuates and
            enhances consumption of ethanol in deprived rats. Paper presented at the
            Behavioral Pharmacology Society Meeting, Annapolis, Maryland, May.

     Lewis, M.J., June, H.L., Perry, L.B., Garnette, M., & Porrino, L.J. (1990). Alteration in
            specific brain activity with stimulant and depressant effects of ethanol. Paper
            presented at the Annual Neuroscience Society Meeting, St. Louis, Missouri,
            November.

     Lewis, M.J., June, H.L., Perry, L.B., Garnette, M., & Porrino, L.J. (1991). Changes in
            regional brain activity with behavioral effects of ethanol and blood ethanol
            concentration. Paper presented at the ACNP Annual Meeting, San Juan, Puerto
            Rico, December.

     June, H.L., Hughes, R.W., Spurlock, H.L., Domangue, K.R., & Lewis, M.J. (1991). Ethanol
            self-administration in freely feeding rats: effects of Ro15-4513 alone and in
            combination with flumazenil (Ro15-1788). Paper presented at the Research Society
            on Alcoholism Annual Meeting, Marco Island, Florida, June.

     June, H.L., Preston, K.L., Bigelow, G.E., & Stitzer, M.L. Buprenorphine effects in
           methadone maintained subjects (1992). Paper presented at the Committee on
           Problems of Drug Dependence Annual Meeting, Keystone, Colorado, June

     June, H.L., Cook, J., Lewis, M.J., & Murphy, J.M. (1997) GABAergic transmission in the
            mesoaccumbens is involved in alcohol motivated behaviors. Paper presented at the
            41st Annual Behavioral Pharmacology Meeting, Ritz Carlton Hotel, Philadelphia,
            PA, May 1997

     June, H.L., Hwang, B.H., & Murphy, J.M. (1997) GABAergic transmission in the meso-
           accumbens is involved in alcohol motivated behaviors in alcohol-preferring (P) and
           outbred Wistar rats. Paper presented at the Annual European Society for
                                                                                       25

       Biomedical Research on Alcoholism in a symposium entitled "Neurobiology of
       alcohol reinforcement", sponsored by the 6th Congress and Karolinska Institute,
       Stockholm, Sweden, June 28-July 1, 1997

June, H., Grey, C., Johnson, T.B., Williams, L., McKay, P., Rock, S., He, X., & Cook, J.M.
       (September 1998). GABAergic substrates in the nucleus accumbens and dorsal
       hippocampus mediate responding maintained by EtOH presentation in alcohol-
       preferring (P) rats. European Behavioral Pharmacology Meeting, Brno, Czech
       Republic

June, H.L., McKay, P.F., Foster, K.L., Mason, D., Cummings, R., Garcia, M., He, X. &
                                              A-Receptor Subunit in the CA1 and CA3
      Hippocamus Regulate Alcohol Responding in “P” Rats. European Society for
      Biomedical Research on Alcoholism, Barcelona, Spain

June H.L., (June, 2002) Alcohol reward is mediated by the GABAA
      the ventral pallidum. Guest Lecturer, Howard University Pharmacology Department,
      Washington, DC

June H.L., (August, 2002) Animal Models: Novel Benzodiazepine Pharmacotherapies to
      Treat Alcohol Abuse, National Medical Association, Honolula, Hawaii

June H.L., (September, 12, 2002) Novel Benzodiazepine Pharmaotherapies to Treat
      Alcohol Abuse: National Alcohol, Tobacco & Drug Addiction Recovery Month, Larue
      Carter Memorial Hospital, Indianapolis, IN

June H.L., (May 2003) Novel Benzodiazepine Pharmacotherapies to Treat Alcohol Abuse,
      Guest Lecturer, Howard University Pharmacology Department, Washington, DC

June H.L., (April 2003) Novel Benzodiazepine Pharmacotherapies to Treat Alcohol Abuse,
      American Society for Pharmacology and Experimental Therapeutics, San Diego,
      CA.

June H.L., (March 2008) Triple Reuptake Inhibitors Reduce Binge Alcohol Drinking and
      Negative Affective States of Withdrawal, Howard University School of Medicine
      Pharmacology Department, Washington, DC

June H.L. (April 2010) Binge Alcohol Drinking: In Search of Its Molecular Target via the
      GABAA Receptor, 5th Annual Leslie H. Hicks Symposium, Howard University
      Psychology Department, Washington, DC

				
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