The Institute for Complex Engineered Systems www.ices.cmu.edu Winter 2010 Newsletter Breaking Ground for Groundbreaking Research: PSII Helps Companies Lead Revolution in Our Infrastructure Pennsylvania Smart Infrastructure Incubator Also in this issue… ICES, Carnegie Mellon University InVivoMon Biomedical device start-up 1201 Hamburg Hall is indebted to PITA funding 5000 Forbes Avenue Pittsburgh, PA 15213-3890 Focused on the Future Phil Campbell, Susan Finger, and Annette Jacobson devote their time to outreach Northrop Grumman Fellows Fernando Cerda Carrizo and Judy Shum are the first to receive the award director’s message This fall has seen a flurry of ICES activity, as this latest issue of iNews will show…from the creation of a new technology incubator focused on critical infrastructure technology; to projects impacting areas as wide-ranging as advances in nano- and micro-technology, and furthering the local econo- my through partnerships between industry and academia. A major event for ICES this fall was the creation of the Pennsyl- vania Smart Infrastructure Incubator (PSII). Together, found- ing partners Bombardier Corporation and IBM and Carnegie Mellon researchers will work to integrate the physical-infra- structure with cyber-infrastructure to enable new capabilities, ensure greater safety and reliability, and contribute to the The Pennsylvania Infrastructure Technology Alliance (PITA) more efficient use of these systems. With $2.2 million in fund- grants continue to yield research that makes a significant re- ing, the PSII will develop new facilities on campus as well as gional impact, strengthening the Pennsylvania economy with in- utilize off-campus testing facilities. Coordinated through ICES, dustry partnerships and technological advances. PITA funding the collaboration will bring together researchers from Civil and has allowed ICES Research Scientist Alan Rosenbloom to de- Environmental Engineering and Electrical and Computer Engi- velop medical devices that monitor molecular events occurring neering and attract more industry and government partners. in a patient’s body by measuring blood glucose and chemo- therapy drugs. He has since received follow-on funding from This issue of iNews also highlights the continued research the National Institutes of Health to establish his start-up com- being conducted by the ICES research centers and clusters. pany InVivoMon and to hire personnel to develop prototypes. Nano- and micro-technology, in particular, have seen signifi- Researchers Michael Bockstaller and Kryzsztof Matyjaszewicki cant advances. The Center for the Environmental Implica- are exploring ways to use nanoparticle additives to improve the tions of Nanotechnology (CEINT@ CMU) recently received a properties and marketability of polymer film coatings. National Science Foundation (NSF) Integrative Graduate Edu- cation and Research Traineeship (IGERT) award to enable Also featured in this issue are news on the scholarship of the graduate students from multiple disciplines to gain proficiency new ICES-Dowd Fellows and the awarding of the first Northrop in the analysis of environmental issues pertaining to nano- Grumman Fellows. Some dedicated faculty have also found technology, decision science, and policy analysis. time in their careers to devote themselves to the educational ef- forts of inspiring and educating the next generation of engineers. Alan McGaughey, assistant professor of mechanical engi- And ICES researchers continue to attract funding from agencies neering, and Yang Wang, Pittsburgh Supercomputing Center that are interested in the research present in our institute. senior scientific specialist, with the Center for Multiscale Mod- eling for Engineering Materials (CM2EM) received NSF fund- I hope that you are inspired by the stories in this issue of iN- ing to support their work on the transport of thermal energy ews. If you are currently involved with ICES research, please by phonons across interfaces in nanostructured materials. send us your good news so we can feature it in future issues. Also, recent work in the Microsystems research cluster has If you inspired by what you read to pursue a new or deeper been focused on microelectromechanical systems (MEMS) relationship with ICES, please feel free to contact me. In the technology with broad ranging applications in chemical sen- meantime, enjoy our good news about what multidisciplinary, sors and in neural prosthetics. high-impact engineering research can achieve. Gary K. Fedder, ICES Director table of contents PITA NEWS Biomedical Device Start-up 8 FEATURE Novel High-Tech Polymer Applications 9 Breaking Ground for Groundbreaking Research 1 OUTREACH CENTER NEWS Focused on the Future 10 IGERT Award Expands Mission of CEINT 4 ICES-PJAS Award Winner Attends SEE 12 New Faculty Members are Familiar CenSCIR Faces 4 ICES Presents! Moving 4th in the Fall 12 NSF Funds Heat Transfer Research at Atomic Level 5 ECE Student Fabricates New Chemical Sensors 6 AWARDS & DISTINCTIONS Neural Prosthetics to Aid Brain Performance 6 Dowd-ICES Fellowship Research Seminar 7 Spotlight on Peter Gilgunn back First Northrop Grumman Fellows 13 cover Pennsylvania Smart Infrastructure Incubator Breaking Ground for Groundbreaking Research: PSII Helps Companies Lead Revolution in Our Infrastructure On a sunny and warm morning in November, researchers with President Cohon noted the potential of this collaborative en- the Institute for Complex Engineered Systems (ICES) along deavor when he said: “It is our vision, one that we share with with industry and government leaders gathered together at all of our corporate and government partners present today, Carnegie Mellon University’s University Center to celebrate that people around the world will also know this region and the groundbreaking of the new Pennsylvania Smart Infrastruc- the state of Pennsylvania as a hub for ‘smart’ infrastructure ture Incubator (PSII). and manufacturing. Today’s groundbreaking ceremony marks an important step in that direction.” This new incubator will integrate the physical-infrastructure that is used every day (transportation and transit systems, The PSII: Bringing Together Diverse Talents buildings, pipes, power grid, concrete and steel) with cyber- infrastructure (computers, networks and sensors) in ways As PSII Co-director Schlesinger – also department head of that will enable new capabilities, ensure greater safety and ECE – stated at the ceremony: “When you talk about infra- reliability, and contribute to the more efficient use of these structure, you are talking about everything.” systems. The development of these technologies will also re- quire a new generation of employees to design, operate, and This partnership of academics, industry, and government maintain new cyber-physical infrastructure systems. The PSII promises to create the opportunity for innovative infrastructure will also help Pennsylvania be a leader in educating workers research as it eliminates boundaries, whether they are intel- to meet the new demand. lectual, institutional, or geographical. PSII founding industrial partners Bombardier Corporation and CMU leadership of the PSII includes three co-directors: IBM, other industry and government representatives, and Schlesinger; Garrett, who also heads CMU’s CEE Depart- Civil and Environmental (CEE) and Electrical and Computer ment; and ICES Director Gary Fedder, who will help integrate Engineering (ECE) researchers broke ground on $2.2 million the incubator into other multidisciplinary research within the in new research facilities designed to support the exploration College of Engineering (CIT). of a variety of critical infrastructure technology areas. Garrett, Jr. adds, “We’ve been working for a number of years Speaking at the official groundbreaking ceremony were CMU on interdisciplinary research to help better manage critical President Jared L. Cohon, PSII Executive Director Matthew infrastructure using advanced technologies. Our goal has Sanfilippo, PSII Faculty Directors T.E. (Ed) Schlesinger and been to deploy a variety of sensors to collect significant James H. Garrett, Jr., President of Bombardier Systems Divi- amounts of new data that can be analyzed and turned into sion Eran Gartner, and IBM Vice President of Corporate Envi- actionable information so that people who build, maintain, or ronmental Affairs and Product Safety Wayne Balta. A number manage infrastructure can do so in a more efficient and cost of PSII research projects were also on display, including the effective manner.” electrical vehicle “ChargeCar,” Bombardier’s autonomous transit vehicle research project, an instrumented natural gas Article continues on page 2… pipeline monitoring project, sensors for energy efficient build- ings, and the Sensor Andrew campus sensing project. 1 Article continued from page 1… of the construction of these new labs is expected by early spring 2011. Initial funding has come, in large part, from founding industry partners Bom- These new facilities will join other campus bardier and IBM in the form of financial facilities, including s Smart Infrastructure assistance and equipment. The Research Consortium, Smart Infrastruc- Commonwealth of Pennsylvania ture Testbed Management Center (Sen- has also provided a significant eco- sor Andrew testbed control center), a nomic development grant through the Smart Infrastructure Test Track Facility (at Redevelopment Assistant Capital Program Bombardier’s existing facility), and a Smart (RACP) to help establish the incubator Infrastructure Field Test Facility (existing and develop the research labs. “We are CMU Robot City site). extremely grateful for this support which has transformed the PSII from a concept Bombardier: Leading Innovative to reality,” says Fedder. Transportation Infrastructure The Western Pennsylvania region ha because of the transformation of its Two new facilities are being built as a part Bombardier Inc., a global leader in rail and of the PSII: 1) the new Bombardier Smart aerospace transportation, has been a long- of the past to a center for knowledge Infrastructure Collaboration Center that will time and valued partner of CIT. As Gartner ogy companies of the 21st Century. be a state-of-the-art distance collabora- notes, “the founding of the PSII builds on tion facility and will allow conferencing the existing relationship between Bombar- ing, but the new Carnegie Mellon/Bombar- of experts in the smarter infrastructure dier and CMU, the genesis of which goes dier collaboration plans to improve these field from around the world for events, back nearly 50 years with the advance- technologies and train a new generation of seminars, and collaborative research and ment of driverless automated transit.” employees to design and operate them. 2) the new IBM Smarter Infrastructure Lab at Carnegie Mellon that will allow for The world’s trillion-dollar network of rails, “Creation of the Bombardier Collaboration research into the management, simulation, roads, bridges, water distribution systems, Center will enable joint research in fields and visualization of data collected from and power networks have varying amounts such as smart guidance systems, rail con- smart infrastructure systems. Completion of automated management and monitor- trol solutions, sensing robotics and so much Chargecar Electronic Guidance for Automated People Movers The ChargeCar project is working to make electric vehicles Bombardier and CMU teamed together to transfer technol- practical and affordable enough to revolutionize urban com- ogy developed for fully autonomous cars (specifically "Boss," muting. These researchers are examining the common ur- the robot Chevy Tahoe that won the 2007 DARPA Urban ban commute to determine if cars powered by predictively Challenge) onto Bombardier’s automated people movers managed supercapacitor-battery systems are a solution (APMs). The proposed future electronic guidance system that can reduce cost of ownership for a commuter car. The will be used to let the APM "see" the track so it can steer ChargeCar team is also working together with researchers at itself. This sensor system will also be able to detect the pres- Bombardier expanding their research to include application ence of obstacles on the track. to Bombardier People Movers. 2 Current PSII Research Projects featured at the groundbreaking event that enhance the efforts of IBM’s Smarter stand exposure to risks, and help predict Planet initiative, IBM’s offerings in Busi- outcomes of management and operational ness Analytics and Optimization, and decisions with greater certainty. CMU’s work within the Center for Sensed Critical Infrastructure Research (CenSCIR). “With CMU’s renowned reputation in engi- The new lab will be a focal point and neering and IBM’s leadership regarding a catalyst for collaboration with like-minded Smarter Planet and business analytics, this research colleagues from IBM Research new lab can drive innovation and develop and across the university, including its en- new technologies to help leaders world- gineering, architecture, public policy, and wide optimize their use of finite resources,” business schools. says Balta. One of the challenges associated with The Future of PSII the development of a smarter infrastruc- as become an international model ture is the massive amounts of data such With founding industry collaborators in- systems will produce. Researchers will cluding Bombardier and IBM, the PSII has economy from the heavy industries collect and analyze this data such as the already begun to attract additional industry e, innovation, and the high-technol- physical condition and energy efficiency and government partners. Within the next – President Cohon of buildings, condition of water pipelines, six months the incubator expects to an- and other infrastructure on which govern- nounce a significant number of more,” said Romuald Ponte, vice president ments, businesses societies, and individu- new partners. of engineering at Bombardier’s Systems als depend. One of the research initiatives Division and the Centre of Competence. the lab will undertake is to explore physical Membership in the PSII is open to com- infrastructures with innovative digital sen- panies that are presently conducting IBM: Analyzing Infrastructure Data sor networks. These networks will produce research with CMU in the area of Smart for a Smarter Planet large amounts of new data that will be Infrastructure, or are actively pursuing a acquired in real-time and integrated with project or proposal with CMU in the area The IBM Smarter Infrastructure Lab at advanced analytical tools. Such analysis of Smart Infrastructure. Carnegie Mellon will develop technologies will be directed to detect patterns, under- Instrumented Pipeline Sensor Andrew The general objective of this project is to research technolo- Sensor Andrew is a large-scale project to create a middle- gies for the monitoring of pipeline delivery integrity, using a ware infrastructure that facilitates communication with sen- network of sensors and controllers to detect and diagnose sors. Currently there are hundreds of sensors deployed developing defects, leaks, and failures. Specifically, these across campus for different purposes, yet there is no single researchers are using ultrasonic waves that are generated by unifying infrastructure that allows researchers to easily ac- small piezoceramic wafers attached to steel pipe specimens cess, manage and utilize these resources. We are devel- in the lab. These waves travel down steel pipe specimens in oping a solution to transform CMU into a living test-bed for the lab and then reflect from flaws or defects. This technique experimenting with a shared sensing infrastructure. is being tested as a way to monitor long distances of pipe. 3 center news IGERT Award Expands Mission of CEINT Researchers at Carnegie Mellon University Gregory Lowry, professor of civil and VanBriesen will be joined in the program (CMU) and Howard University have re- environmental engineering and director of development and implementation by a ceived a five-year, $3.15 million grant from the Center for Environmental Implications cadre of professors including: Lowry; Eliza- the National Science Foundation (NSF) to of Nanotechnology at CMU (CEINT@CMU) beth Casman, associate research profes- launch a new interdisciplinary program in explains that “the IGERT will serve an im- sor of engineering and public policy; and the environmental effects and policy impli- portant role in expanding the educational Kimberly L. Jones and Lorraine Fleming, cations of nanotechnology. Funding from mission of CEINT. It will develop a cur- both professors in civil and environmental a new NSF program called the Integrative riculum specifically for IGERT and CEINT engineering at Howard University. Graduate Education and Research Trainee- Ph.D. students that complements the ship (IGERT) will enable the creation of research and educational activities already Additional Carnegie Mellon faculty partici- interdisciplinary programs educating U.S. underway in CEINT.” pants in this NSF-funded project include: Ph.D.s in science and engineering. Allen Robinson, professor of mechanical Graduate students from multiple disci- engineering; Kelvin Gregory, assistant “The IGERT program at Carnegie Mellon plines will participate in a two-year training professor of civil and environmental en- and Howard will operate at the interface program to learn the fundamentals of gineering; Kris Dahl, assistant professor of science and environmental policy to their core disciplines and gain proficiency of biomedical engineering and chemical produce an environmentally and policy in the analysis of environmental issues engineering; Michael Bockstaller, associate literate generation of nanoscience profes- pertaining to nanotechnology, deci- professor of materials science; Moham- sionals with the skills needed to create sion science, and policy analysis in new mad Islam, assistant professor of materials novel nanotechnologies and to assess and nanotechnology-themed courses. Follow- science and chemical engineering; and manage environmental risks associated ing this foundation, students will conduct Paul Fischbeck, professor of social and with nanomaterials,” said Jeanne M. Van- research at the interface of policy and decision sciences and engineering and Briesen, professor of civil and environmen- nanotechnology. Students also will partici- public policy. Additional Howard faculty tal engineering who will lead the program. pate in international laboratory exchange participants include Gary Harris, professor projects as well as internships at corpora- of electrical and computer engineering. tions active in nanotechnology. e New Faculty Members are Familiar CenSCIR Faces Once doctoral students and now faculty members, Mario extends the work he did as a Ph.D. student. Working on Berges and Anthony Rowe continue their work with the Cen- embedded and distributed systems and sensor networks, ter for Sensed Critical Infrastructure Research (CenSCIR). As his research has focused on the development of large-scale doctoral students, Berges and Rowe were involved with the sensor networks that are energy-efficient and provide real- Sensor Andrew project, a large-scale effort to widely deploy time properties. Rowe says, “I see sensor networking as a sensing devices across Carnegie Mellon’s campus and practical mechanism for bringing contextual information and create a living laboratory for real-world infrastructure chal- new abilities to the already numerous embedded systems that lenges. Today, they continue working on critical infrastructure surround us.” research as Carnegie Mellon engineering faculty members. As faculty members, their work together continues. In As a Ph.D. student, Berges’ work focused primarily on devel- November, they presented on “Contactless Sensing of Ap- oping a framework for enabling detailed energy-awareness in pliance State Transitions” with ECE Professor Ragunathan buildings through minimally-intrusive approaches. Now as an Rajkumar at the 2nd Association for Computing Machinery assistant professor in the Civil and Environmental Engineering (ACM) Workshop on Embedded Sensing Systems for Energy- Department, Berges says he is “more generally interested in Efficiency in Buildings. instrumenting our civil infrastructure to increase its resilience, adaptiveness, and self-monitoring capabilities.” “As well as continuing to work together on the Sensor Andrew project,” Berges reports, “we have started to leverage this Rowe is now an assistant research professor in Electrical work to develop a variety of applications in the areas of build- and Computer Engineering and conducting research that ing energy management, worker safety, etc.” o 4 NSF Funds Heat Transfer Research at Atomic Level Alan McGaughey, associate professor interfaces with atomic-level precision. calculations to study the mechanisms of of mechanical engineering, and Yang When such interfaces are separated by thermal transport by phonons across these Wang, Pittsburgh Supercomputing Center distances that are one thousandth to one interfaces. He is doing this by using atom- senior scientific specialist, have received a millionth the width of a human hair, as they istic modeling tools including lattice dynam- National Science Foundation (NSF) award are in computer chips and light-emitting ics calculations, the Boltzmann transport to support their work on the transport of diodes, they can cause thermal resis- equation, molecular dynamics simulations, thermal energy across interfaces in nano- tances much higher than what would be and density functional theory calculations. structured materials. This is one of several expected from standard models. High projects being conducted within the Center thermal resistance makes it difficult to Wang – an expert in density functional for Multiscale Modeling for Engineering remove heat, leading to undesirably high theory, a computational method for doing Materials (CM2EM). operating temperatures. quantum mechanical calculations – per- forms these needed calculations so the Nanostructured materials are used in the McGaughey explains: “This research is model predictions can be compared to semiconductor and energy industries as important because it is very difficult, if experimental measurements. He is also components in field-effect transistors, not impossible, to carry out experiments very familiar with the large-scale comput- lasers, and light emitting diodes. The at such small length scales. Atomic-level ing facilities available at the Pittsburgh small length scales lead to closely-spaced modeling allows us to ‘observe’ what is Supercomputing Center, which they need interfaces that allow for the indepen- happening at the nanometer scale and to carry out these calculations. dent control of electrons (electricity) and use this information to identify fundamental phonons (heat) and how they interact with physical mechanisms and to better under- “This funding will further nanoscale thermal photons (light). stand experimental observations.” transport research by providing an oppor- tunity to dig deeper into how atomic–level In this project, McGaughey and Wang will Specifically, McGaughey is performing structure influences behavior at larger model heat transfer across solid-solid computer simulations and theoretical length scales,” says McGaughey. ence is measured in the microdialysate tubing. orrection of glucose levels in tracer. Mario Berges Anthony Rowe 5 center news ECE Student Fabricates New Capacitive Chemical Sensors Advances in capacitive chemical sensors have benefitted With funding received from the National Institute for Occupa- from the union of sensor technology and microelectromechan- tional Safety and Health (NIOSH), Lazarus worked specifical- ical systems (MEMS). MEMS sensors are very sensitive, have ly on the application of including chemical sensors in masks quick response times, and use less power in the detection of used in industrial plant settings. chemicals in their environment. It is with this kind of research that Nathan Lazarus, a doctoral student in Electrical and These techniques have been successfully demonstrated for Computer Engineering (ECE), has been involved. “I primarily humidity sensing and have led to publications in the Journal work on techniques for integrating several types of chemical of Microelectromechanical Systems, the Proceedings of the sensors with interface electronics,” explains Lazarus. Solid-State Sensor, Actuator, and Microsystems Workshop 2010, and the Proceedings of the 2009 IEEE International Conference on MEMS (MEMS 2009). His future efforts will be focused on investigating other capacitive materials and dem- onstrating that these sensors can be used for a wide variety of chemicals, rather than simply for water vapor. “His research began by working on humidity sensors and chemiresistor noise modeling in order to prove design con- cepts in fabricating integrated chemical sensors in foundry CMOS processes,” says Gary Fedder, Nathan’s faculty advi- sor, Howard M. Wilkoff Professor of ECE, and ICES Director. Lazarus explains that the latest focus of his research has SEM image of a sensor (a) before and (b) after inkjetting of been on sensors “for use in gas mask cartridges in order to polymer with inset picture of filled release holes notify the user that chemicals have almost filled the cartridge and are about to leak into the facemask.” Lazarus has investigated several methods for improving the sensitivity of these chemical sensors by using MEMS In order to reach the regulatory limits of detection for gas micromachining, specifically using an integrated capacitive masks, he has been developing a technique for lowering the humidity sensor on-chip with complementary metal-oxide- limit of detection of gold nanoparticle chemiresistors. This semiconductor (CMOS) interface electronics. Integrating type of sensor experiences higher noise at low frequencies, chemical sensors on the same silicon die as that on which but is typically measured at close to 0 Hz. By modulating electronics is tested has the potential to reduce fabrication the input voltage and measuring the sensors at high frequen- costs because it shares process steps. Eliminating the need cies, the noise can be reduced, allowing a smaller amount of to take signals off chip to external circuitry also reduces noise chemical to be detected. in the system, improving the lower limit of detection. Neural Prosthetics to Aid Brain Performance The Center for Implantable Medical Microsystems Neural prosthetics are implanted medical microsystems used (CIMM) at ICES is teaming with leading neuroscience to stimulate or record activity in a single brain cell or small researchers from the University of Pittsburgh to develop ensembles of brain cells. They help Parkinson's sufferers con- a new generation of neural prosthetics whose mechani- trol their tremors and will ultimately enable direct brain control cal properties better match those of the brain. Their of artificial limbs and increase cognitive abilities. Current hypothesis is that compliance-matched neural prosthet- state-of-the-art prosthetics operate reliably in living brains for ics will maintain their performance over the lifetime of periods up to months before their performance degrades. the prosthetic recipient. This failure mode precludes long-term chronic use and limits them to acute clinical scenarios. 6 awards & distinctions Seminar Highlights Dowd-ICES Fellowship Research The fall is always a busy and exciting time for the Dowd-ICES • Minhua Qiu - “Nanometer Resolution Imaging and Com- Fellowship. Not only are four new fellows awarded, but the putational Analysis of Axonal Transport Defects in Drosophila ICES community has the opportunity to hear about their fund- Models of Alzheimer’s Disease” (advisor: Ge Yang, BME); ed research at the annual Dowd-ICES Fellowship Seminar. • Mary Beth Wilson - “Thermally Reversible Polymers for Engi- This year was no different. The 2010 Fellows were an- neering 3D Synthetic Vascular Networks” (advisor: Phil Leduc, nounced this summer and include doctoral students Ethan BME/ME, with collaboration from Burak Ozdoganlar, ME). Demeter from Chemical Engineering, Catherine Izard from Civil & Environmental Engineering and Engineering & Public The 2009 Fellows presented on the research they conducted Policy, Minhua Qiu from Biomedical Engineering, and Mary during their 2009-2010 fellowship tenure: Beth Wilson from Biomedical Engineering. • Christopher Highly (BME) - “MEMS Technologies for Mi- The seminar was held on October 27 in conjunction with crocapsule-based Complex Tissue Engineering Constructs” fellowship donors Philip and Marsha Dowd’s annual visit to (advisor: Stefan Zappe, BME); campus. At this event, the new 2010 Fellows, along with the 2009 Fellows and the 2009 Dowd Teaching Fellow, presented • Jueun Lee (ME) - “Investigation of Bone and Cartilage their research. Drilling for Orthopedic Surgery” (advisors: Burak Ozdoganlar, ME, and Yoed Rabin, ME); The 2010 Fellows presented on the research they will under- take during the 2010-2011 academic year: • Jacob Melby (MSE) - “Polarization Engineering in III Nitride-based Optoelectronic and Sensor Device” (advisors: • Ethan Demeter - “Porous, Decorated Metal Electrodes for Lisa Porter, MSE, and Robert Davis, MSE); Oxygen Evolution in Water Splitting Applications” (advisor: John Kitchin, CE); • Scott Peterson (EPP) - “Vehicle to Grid Services: Integrat- ing PHEVs with the Grid” (advisors: Jay Apt, Tepper/EPP, and • Catherine Izard - “Dynamic Assessment of Infrastructure Jay Whitacre, MSE). Flows in a Climate-constrained U.S. Electricity Sector” (advi- sor: H. Scott Matthews, CEE, with collaboration from Ines de 2009 Dowd Teaching Fellow Marija Ilic presented on “The Lima Azevedo, EPP); Challenges and Opportunities in Educating Electric Energy Systems.” Ilic is a professor of electrical and computer engi- neering and engineering and public policy. Back row (l tor): Scott Peterson, Jacob Melby, Christopher Highly, Ethan Demeter Front (l tor): Marija Ilic, Mary Beth Wilson, Jueun Lee, Philip Dowd, Marsha Dowd, Minhua Qiu, Catherine Izard 7 pita news By 2007, ICES Research Scientist Alan development,” Rosenbloom explains. “In Rosenboom had understood how to our case, PITA funding has allowed us create medical devices that can monitor to bridge this gap. In turn, the funding molecular events occurring in a patient’s from secondary grants has allowed us to body. Specifically, he conceptualized establish Invivomon and to develop our tools that would allow for the continuous prototypes into medical devices.” monitoring of the bloodstream in order to measure blood glucose and chemo- The secondary grants that Rosenbloom therapy drugs. However, he did not yet mentions are two National Institutes of have the financial means to develop these Health (NIH) Small Business Innovation devices as products. Research grants the company recently received. These NIH grants have provided His vision would soon become a reality. In funding for Rosenbloom and Subrebost that same year, Rosenbloom was awarded to establish and equip InVivoMon as a PITA funding that allowed him to test his start-up biomedical engineering research ideas, build prototypes, collect preliminary company, to hire Subrebost as CEO and data, and apply for competitive, follow-up company engineer Heer Gandhi as a grants. Two years later, he and his former company engineer, and to hire consultants postdoctoral fellow, now business partner – to help develop their prototypes. George Subrebost have created the spinoff company InVivoMon, Inc., which focuses The first grant funding allows for the on creating practical, wearable systems development of a continuous bloodstream that are able to monitor patients’ molecular glucose monitoring system. The completed events in real time. system will incorporate sophisticated algo- rithms to allow precise glucose level control The goal of the company is to use the in critically ill patients. The second grant, latest engineering technology to create awarded in September, funds the develop- robust, clinically useful tools that improve ment of a system that will allow individu- the quality of medical diagnostics available alized dosing of cancer chemotherapy Close-up of the imaging region where fluoresce to physicians and treatment available to pa- drugs. The system will incorporate phar- tients. Its platform technology is based on macokinetic modeling to produce optimal continuous blood monitoring via intravenous therapeutic levels, sharply limiting toxicity. microdialysis. This technology eliminates repeated testing and allows for continuous The benefits from the devices that In- adjustments of metabolite or drug levels VivoMon is developing include precise that are smoother, quicker, and safer. management of cancer chemotherapy and insulin infusion for tight control of glucose A fundamental requirement for microdialy- blood levels in the critically ill and also in sis to become a clinical tool is that col- post-operative cardiac surgery patients. lected analytes truly reflect the composi- tion in the blood. InVivoMon is developing PITA funding has also helped Rosenbloom microdialysis technologies that will eventu- to explore new targets for next generation ally lead to a medical embedded system patient monitoring. A pilot project will de- with calibration, safety alarms, and wireless velop near real-time monitoring of Procalci- communication of analyte levels. tonin, a peptide, in the blood. Procalcitonin is a marker of bacterial infection. The goal “It’s difficult to imagine how this work is to detect hospital acquired infection would have progressed nearly as far and early, so that treatment can begin rapidly. fast as it has without the funding from This technology will be developed in col- PITA,” states Rosenbloom. laboration with Rockland Immunochemi- cals, Inc. (Gilbertsville, PA). Rockland has “In reality, there is a large gap in funding long-standing expertise in the develop- The printed circuit board that performs error-co between theoretical realization and product ment of highly sensitive immunoassays. by measuring the concentration of a fluorescei 8 PITA-Supported Research Enables Novel High-Tech Polymer Applications A variety of products like micro- Specifically, they have been electronics and protective and op- developing nanocomposite mate- tical coatings rely on polymer thin rials that can resist wear and cor- films. These tiny high-tech coat- rosion, have improved thermome- ings applications allow not only chanical properties, and provide for further miniaturization of prod- shielding against undesirable ucts like these, but also contribute radiation while maintaining opti- to energy efficiency because cal transparency. they are lighter in weight and less energy is used in their production. “The unique combination of ma- However, polymer thin films still terial properties that are typically face the limitations of not being as mutually exclusive is enabled by stable as other materials and are a novel technique developed in not yet able to be manufactured in the Matyjaszewski lab that facili- a way that meets both economic tates the control of the molecu- and aesthetic demands. lar architecture of the particle fillers,” Bockstaller describes the A solution to this situation lies research. “The combination of with the use of nanoparticle ad- these properties allows for new ditives to improve the properties material applications along with of polymer film coatings. With more aesthetic design possibili- this in mind, Associate Professor ties and thus, a greater chance of Materials Science and Engi- of marketability.” neering Michael Bockstaller and the J.C. Warner Professor of the PITA seed funding has enabled Natural Sciences and University them to provide a proof-of- Professor Kryzsztof Matyjasze- concept evaluation of an original ence is measured in the microdialysate tubing. wiski were given the opportunity approach to creating transparent with Pennsylvania Infrastructure polymer nanocomposite thin films Technology Alliance (PITA) fund- with improved thermomechanical ing to address this need. properties. In addition, they have been able to secure government With the help of PITA funding, grants to further develop the they have been able to create an approach. For example, they re- original approach to understand ceived a grant from the Air Force the effect nanoparticle additives Office of Scientific Research have on the thermomechanical (AFOSR) to develop novel protec- and optical characteristics of tive radiation shields based on particle-filled polymer thin films. these novel material systems. “Receiving the PITA grant allowed The materials created from this us to explore a high risk col- research have also been used as laborative project that aimed to demonstration models in a new resolve a fundamental challenge nanotechnology course at Carn- in the area of polymer nanocom- egie Mellon University that is part posite materials,” Bockstaller of an effort to enhance undergrad- explains. “The materials that were uate education in nanotechnology. developed in this project not only satisfy scientific curiosity but expand the range of marketable orrection of glucose levels technology areas for polymer- n tracer. based materials.” 9 Faculty Devote Their Time to Outreach Educational outreach programming relies strongly on the devotion individual faculty members give to these endeavors, and ICES outreach is no different in this regard. It has benefitted from faculty members like Phil Campbell, Susan Finger, and Annette Jacobson who have given their time, expertise, passion, and commitment to furthering engineering outreach education. As well, current director Gary Fedder, ICES research faculty member Ender Finol, and former director Cristina Amon have played key roles in shaping what ICES outreach has become. The Western Pennsylvania region ha because of the transformation of its Seeing the Bigger Picture and Surfaces (CPS) Laboratory in order to of S.T.E.M. Education provide a facility equipped to promote sci- of the past to a center for knowledge ence and engineering education to youth ogy companies of the 21st Century. Annette Jacobson is driven by the larger and the public. picture of how individual teaching mo- ments, both formal and informal, contrib- Benefitting from the CPS Lab and Jacob- ute to the development of students. In son’s teaching was Connecting Science her current role as the associate dean for with Engineering and Technology (C-SET), undergraduate studies in the College of a Pennsylvania Infrastructure Technol- Engineering and teaching professor in ogy Alliance (PITA) funded professional Chemical Engineering, she sees in the development program for area S.T.E.M. undergraduate engineering student body, educators. The goal of the C-SET project young adults who have benefited from a was to create a collaborative effort be- series of teaching and mentoring moments tween Carnegie Mellon engineering faculty that have led them to study engineering at and area S.T.E.M. teachers in order to CMU. She also sees, now more than ever, prepare introductory engineering content a greater push and need for K-12 S.T.E.M. in modular form which teachers can use in (science, technology, engineering, math- their classrooms. ematics) educational opportunities. As well, Jacobson has been involved Jacobson’s tenure with ICES educa- with engineering programming for girls. tional outreach began in 1995 when she After having taught separate engineer- became involved with Moving 4th Into ing activities for middle and high school Engineering, an ICES program that invites girls in the Engineering Your Future (EYF) local 4th graders to campus and engages program, she, CPS Program Associate them in a variety of fun hands-on engi- Director Rosemary Frollini, Finger and neering activities. Every year, she leads Fedder created the Summer Engineering an activity called “Fun with Polymers,” in Experience for Girls (SEE) program to be which students learn about applications housed in and run by ICES. Since 2007, of polymers and how chemical engineers she has been involved with the planning develop products with these materials, of the program and teaching an activity which include some of their favorite things, with Frollini on the environmental effects of like gummy worms and superballs. climate change. Pictured above (from the top down): In 1998, her involvement in outreach was Catching the “A-ha!” Moment Phil Campbell, Annette Jacobson, enhanced when PPG Industries provided Ender Finol, and Susan Finger funding to Chemical Engineering to reno- When Civil and Environmental Engineering participating in ICES outreach. vate the PPG Industries Colloids, Polymers Professor Susan Finger was in high school, 10 outreach course gives undergraduates the oppor- Mark Krotec and former Duquesne tunity to explore and evaluate rapid and University professor John Doctor. The virtual prototyping in the context of col- underlying assumption of the program laborative design. One of the projects she is that one of the roles of a teacher is has her students consistently undertake is as an advocate, as one who will learn the development of activities that introduce and then go on to teach and train other fourth grade students to engineering con- teachers. Together, they created a cepts. This activity has been a consistent program that gives premier middle component of Moving 4th Into Engineering, and high school science teachers from and Finger has always had her students Southwestern Pennsylvania the oppor- participate and work with the Moving 4th tunity to intern in a research engineer- children on their various projects. ing lab and develop related activities and lessons that can then be taught in As well as working with Moving 4th Into a school science class. Engineering, Finger was one of the EYF as become an international model faculty who made the decision to create One of the resulting activities was and house the SEE program in ICES. For the Build a Bone activity which has economy from the heavy industries the past four summers, Finger has devoted become the ICES signature activity e, innovation, and the high-technol- extensive time, effort, and enthusiasm to presented each year at National Engi- – President Cohon working with each cohort. She not only neers Week at the Carnegie Science leads each cohort of girls in an introductory Center. Build a Bone was developed engineering activity and a mathematical by Krotec during this tenure as a units of conversion refresher class, but she Teachers Teaching Teachers intern as works with them continually throughout an activity to use with his students. It the two weeks on their individually chosen has become a consistent favorite ICES research topics and presentations. activity at the annual National Engi- neers Week event. Affecting Students of All Ages and Backgrounds Continuing the Tradition she volunteered at a nursery school pro- Phil Campbell has always loved teach- ICES outreach has truly benefitted from gram. She remembers those times when ing. And he shares a similar motivation as the passion and devotion its participat- she had the good fortune to observe a child Susan Finger: “seeing it all go off in a stu- ing faculty and graduate students have having an “a-ha!” moment, when a child dent’s head…that aha moment…it makes for passing their love of engineering on would figure out how to play with a particu- it all worthwhile.” For Campbell, learning is to the next generation. This commit- lar toy or notice something for the first time. truly a lifelong process. He loves to teach ment has motivated ICES Director Gary And she remembers the thrill of being wit- students of all ages and to experience the Fedder, who leads annually the SEE ness to it. The joy of being a part of such a moment when he sees them understand a girls in his electrical energy conserva- moment has fueled her love of teaching. concept or idea. It doesn’t matter if it is the tion activity and encourages them to four-year old engaging in the “Build a Bone” overcome gender stereotyping and Finger’s involvement with engineering out- ICES educational activity at the annual follow their love of S.T.E.M. reach began when she became involved National Engineers Week event or a senior with the EYF program. Her involvement citizen learning something new in one of Also committed, ICES research faculty with outreach in the Engineering Design Campbell’s Adult Lifelong Learning classes. member Ender Finol leads his rocket Research Center (EDRC) – the National assembly and launching activity annu- Science Foundation (NSF) center from “What keeps it fresh for me is the range ally at Moving 4th Into Engineering. As which ICES evolved – began in 1996. of students,” he explains. And the differ- a CMU doctoral student, Finol became Since the EDRC was created as an NSF ent classes, presentations, and activities involved with Moving 4th in 1998 when engineering research center, outreach was Campbell has taught to students from ages his advisor, Cristina Amon, asked him a mandated component of the center’s ranging from four to ninety four is extensive. to assist her with the rocket activity, efforts. To help the center meet this need, which she directed at that time. Now Finger created an outreach component to One of the significant activities Campbell as a faculty member, he continues to her course Rapid Design through Vir- names is the Teachers Teaching Teachers lead this activity instilling in his stu- tual and Physical Prototyping, which she program, which he founded with Central dents the need to help shape the next continues to offer and teach today. This Catholic High School science teacher generation of engineers. 11 outreach recently awarded ices grants ICES-PJAS Award Winner Attends SEE Recent ICES Awards Prior to attending ICES’s Summer BIOENGINEERING TECHNOLOGIES FACULTY Engineering Experience for Girls (SEE) this past summer, Maria Melchiorre had Phil Campbell, funded by National Institutes of already distinguished herself by winning Health - Center for Disease Control “Engineering an ICES Societal Impact Award (Middle Differentiation of Multi-Tissue Units” School) at the Pennsylvania Junior Academy of Science (PJAS) Region 7 Competition in February. A rising 8th grade CENSCIR/PSII FACULTY student at St. Sebastian School in the North Hills, Maria won for her project on “Color of Light and Heat Absorbed by a Bombardier, IBM, and a Pennsylvania Redevelop- Solar Collector.” The award money she received helped to ment Assistance Capital Program (RACP) grant fund her trip to the PJAS State Competition at the Pennsylva- have provided funding to help found the Pennsylva- nia State University in May. nia Smart Infrastructure Incubator. Other 2010 ICES-PJAS winners included: José M.F. Moura and Irving Oppenheim, funded by Westinghouse Electric Company, “Time Reversal • Societal Impact Award, High School: Smriti Vats, The Ellis Acoustics for Online Monitoring of a Nuclear Steam School, for her project on “Devising a Rapid Test for the Supply System” H1N1 Influenza”; CEINT FACULTY • Interdisciplinary Science Award, Middle School: Emily Yaruss, The Ellis School, for her project on “How Does Algae Jeanne VanBriesen, funded by the National Sci- Affect the ph in Different Types of Solution?”; ence Foundation, “IGERT: Educating at the Inter- face: Nanotechnology-Environmental Effects and • Interdisciplinary Science Award, High School: Ishan Chat- Policy (EI-NEEP)” terjee, Fox Chapel Area High School, for his project on “Anti- oxidant Remediation of Oxidative Stressed Stem Cell Line.” CM2EM FACULTY Kaushik Dayal, funded by the Solid Mechanics ICES Presents! Program, Mechanical Sciences Division, Army Moving 4th in the Fall Research Office, “Dynamics of Structural Phase Transformations using Molecular Dynamics” This year, ICES was pleased to offer a new fall version of our highly successful educational outreach program, Mov- MICROSYSTEMS FACULTY ing 4th Into Engineering. Moving 4th in the Fall was led on Saturday, November 20 th by Chemistry professors Catalina Gary Fedder, funded by the Defense Advanced Re- Achim and Subha Das. The two professors led participating search Projects Agency, “Stirling MicroCooler Array students in new activities that show the art and science of with Elemental In-Plane Flow” light, color, cooking! Participating area 4th grade students hail from Colfax Accelerated Learning Academy, Liberty STEINBRENNER INSTITUTE FACULTY Elementary, Edgewood Elementary, and Assumption School. David Dzombak, funded by Colcom Foundation, “Steinbrenner Institute U.S. Environmental Sustain- ability Doctoral Fellowship Grant” Deborah Lange with Heritage Community Intia- tives, funded by United States Department of Labor Recovery Act, “Energy Training Partnership Grant”. The goal is for these organizations, along with local and regional business and academic leaders, to put their resources together during a 10-week training program this past summer in the hopes of making western Pennsylvania a green-friendly metro area. In Braddock, PA, they retrained 22 local workers into green collar employees and boosted both local economic growth and energy efficiency. 12 ICES Announces the First Northrop Grumman Fellows This past August, ICES announced the very first Northrop The Northrop Grumman Fellowship was established through Grumman Fellows: Fernando Cerda Carrizo and Judy Shum. an endowment gift given to ICES (then the Engineering De- Carrizo and Shum have received these fellowships for the sign Research Center) in 1988 by Litton Industries, now part 2010-2011 academic year for the academic excellence and of the Northrop Grumman Corporation. The Northrup Grum- high research productivity they have demonstrated in their man Fellowship provides merit-based awards to doctoral stu- doctoral work, as well as for the relevance of their work to dents in the College of Engineering (CIT) who are conducting ICES’s research strategic directions. multidisciplinary research that is associated with strategic directions within ICES. The 2010-11 awards mark the first Temporarily on leave from the faculty of the Department of time the Northrop Grumman Fellowship has been awarded. Civil Engineering at the Universidad de Concepcion, Carrizo has been a Ph.D. student in the Department of Civil and En- vironmental Engineering (CEE) at Carnegie Mellon University since the fall of 2008. He has been conducting his research with Thomas Lord Professor & Head of CEE James H. Garrett and University Professor Jacobo Bielak to develop a vehicle-data-driven approach for assessing damage in bridge structures using multi-resolution signal processing techniques. Judy Shum has been a familiar face at ICES since she began her doctoral program three years ago. She has been working with ICES Associ- ate Research Professor Ender Finol and the Vascular Biomechanics and Biofluids Laboratory on develop- ing a diagnostic tool that can automatically calculate a set of features to characterize the geometry of abdominal aortic aneurysms. Save the Date: Thursday, April 7, 2011 ICES Anniversary Symposium Calling all ICES readers! Be sure to save Thursday, April in multidisciplinary engineering research. It will also be 7, 2011 for the ICES Anniversary Symposium. This event an opportunity to see old and new faces, who represent will be held in honor of the 25th anniversary of the creation collectively the history of the EDRC and ICES. of Engineering Design Research Center (EDRC), the precursor of ICES. The EDRC was a National Science Foundation Engineering Research Center that was established in CMU’s College of The ICES Symposium will feature talks on strategic research Engineering in 1986. On February 1997, the Dean of the areas within ICES, as well as talks that reflect on the past College of Engineering announced the creation of ICES from lessons learned through EDRC and ICES research. This will the infrastructure of EDRC. be an opportunity for academic researchers and industry and government affiliates to network and discuss issues More information on the ICES Symposium will be sent out shortly. 13 Every day at CMU provides an opportunity to challenge myself to be a better engineer, scientist and human. I like working at CMU and ICES because these faculty members truly live their worldwide reputation for excellence, practical results, interdisciplinary collaboration and heartfelt fascination for research. — Peter Gilgunn Peter Gilgunn is no stranger to ICES. Since 2003, he has been affili- ated with the Institute: first, as a principal process engineer with the company Bridge Semiconductor; then, as a doctoral student in Electri- cal and Computer Engineering (ECE); and now, as a postdoctoral fellow. And throughout this ongoing relationship, Gilgunn has brought his passion for microtechnology research to the task at hand, while continuing to enhance his expertise working on diverse projects with engineering faculty and graduate students. “My interest in microtechnology began in the semiconductor industry where I made high frequency bipolar chips and dynamic random ac- cess memory (DRAM) modules,” Gilgunn explains. “I became fasci- nated with the possibilities of enhancing micromechanical systems by integrating electronic and mechanical functions at microscopic scales.” Gilgunn joined Bridge Semiconductor to work on an ICES-collaborative infrared sensing product that used microstructures as the sensing ele- ment. A year later, he applied and was accepted at CMU to work on a Ph.D. with Howard M. Wilkoff Professor of ECE and ICES Director Gary Fedder on microelectromechanical systems (MEMS). As a doctoral student, Gilgunn’s work focused on high-density arrays of micromirrors for scanning applications like laser range finders and optical communications. The mirrors were made with a technology called SOI-CMOS-MEMS (SOI: Silicon-On-Insulator; CMOS: Comple- mentary Metal-Oxide-Semiconductor). “Peter’s doctoral research is a tour de force in creating the fabrication technology needed to batch assemble CMOS MEMS actuation with ultra-flat, high fill factor SOI mirror arrays,” Fedder states. He further Spotlight on Peter Gilgunn: explains that the hybridization of these characteristics in a device provides for independent optimization of the SOI mirrors and CMOS- A Familiar Face MEMS electrothermal actuators. The use of CMOS-MEMS enables in Microtechnology Research the future integration of onboard sensing, control, and signal condi- tioning functions. Currently as a postdoctoral fellow for Fedder and ECE Professor Tamal Mukherjee, Gilgunn is diversifying his expertise and working on two different projects. One of his projects involves neural prosthetics, and the other undertakes the creation of a micro- and nano- electrome- iNews Acknowledgements chanical systems (MEMS/NEMS) cyber-design community. Editor and Writer: Alicia Brown Angemeer The neural prosthetic project is one of several projects being conduct- Designer: Tim Kelly ed by the Center for Implantable Medical Microsystems (CIMM) and Contributing Writers/Editors: entails the long-term implantation of electrical probes for brain stimula- Michael Bockstaler, Peter Gilgunn, Nathan tion and signal extraction. Lazarus, Alan McGaughey, Matt Sanfilippo, Chriss Swaney The goal of the MEMS/NEMS cyber-design community project is to create a “self-sustaining, collaborative, online community of micro- To read more about ICES, please visit our system and nanosystem designers ranging from novices to experts website at http://www.ices.cmu.edu/. that will provide open source intellectual and simulation resources,” describes Gilgunn.
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