Neurology and Clinical Neuroscience by chenmeixiu


									Neurology and
Clinical Neuroscience

Clinical MR
Diffusion, Perfusion
and Spectroscopy
Edited by Jonathan H. Gillard
University of Cambridge, UK
Adam D. Waldman
Charing Cross Hospital, London, UK
and Peter B. Barker
The Johns Hopkins University, Baltimore, USA
The physiological magnetic resonance
techniques of diffusion imaging, perfusion
imaging and spectroscopy offer insights
into brain structure, function and metabolism.
This book provides the reader with a thorough review of the underlying physical
principles of each of these methods, as well as comprehensive coverage of their                  Neurodegenerative Diseases
clinical applications. Attention is also drawn to possible artifacts and pitfalls                Neurobiology, Pathogenesis and Therapeutics
associated with these techniques. This book is an essential reference work for
radiologists, neurologists, neurosurgeons and psychiatrists who use these techniques,            Edited by Flint Beal
as well as medical researchers, residents and fellows.                                           Cornell University, New York
                                                                                                 Anthony E. Lang
                                                                                                 University of Toronto, Canada
• Comprehensive review of advanced MRI techniques and
  applications                                                                                   and Albert Ludolph
• Explains clinical applications                                                                 Universität Ulm, Germany
• Case reports included throughout the book                                                      This major reference reviews the rapidly advancing knowledge of neurodegenerative
Contents: 1. Fundamentals of MR spectroscopy; 2. Quantification and analysis in MR               diseases in the context of a comprehensive survey of each disease and its clinical
spectroscopy; 3. Artifacts and pitfalls in MR spectroscopy; 4. Fundamentals of diffusion MR      features. The editors and contributors are among the leading experts internationally.
imaging; 5. MR tractography using diffusion tensor MR imaging; 6. Artifacts and pitfalls in      Covering basic science, diagnostic tools and therapeutic approaches, the book focuses
diffusion MR imaging; 7. Cerebral perfusion imaging by exogenous contrast agents; 8. MR          on all aspects of neurodegenerative disease, including the normal aging process. In
perfusion using arterial spin labeling; 9. Artifacts and pitfalls in perfusion MR imaging;
                                                                                                 each case the underlying genetics, neuropathological and clinical issues are fully
10. Cerebrovascular disease: overview; 11. MR spectroscopy in stroke; 12. Diffusion and
perfusion MR in stroke; 13. Arterial spin labeling in stroke; 14. Magnetic resonance diffusion   reviewed, making this the most complete as well as the most authoritative reference
tensor imaging in stroke; 15. MR spectroscopy in carotid disease; 16. Diffusion and              available to clinicians and neuroscientists.
perfusion MR imaging in carotid disease; 17. Imaging migraine pathogenesis; 18. Adult            Features
neoplasia: overview; 19. MR spectroscopy of brain tumors in adults; 20. Diffusion MR
imaging in adult neoplasia; 21. Perfusion MR imaging in adult neoplasia; 22. Physiological       • Largest and most comprehensive reference text on
imaging in infection, inflammation and demyelination: overview; 23. MR spectroscopy in             neurodegenerative disease
intracranial infection; 24. The role of diffusion-weighted imaging in intracranial infection;    • Editors and contributors include the world’s leading authorities
25. MR spectroscopy in demyelination and inflammation; 26. Diffusion imaging in demyeli-           internationally
nation and inflammation; 27. Physiological MR to evaluate HIV-associated brain disorders;        • Covers basic neuroscience and clinical
28. Seizure disorders: overview; 29. MR spectroscopy in seizure disorders; 30. Diffusion and       features
perfusion MR imaging in seizure disorders; 31. Psychiatric and neurodegenerative disease:
overview; 32. MR spectroscopy in psychiatry; 33. Diffusion MR imaging in psychiatry and          Contents: Part I. Basic Aspects of Neurodegeneration; Part II. Neuroimaging in
aging; 34. MR spectroscopy in aging and dementia; 35. MR spectroscopy in                         Neurodegeneration; Part III. Therapeutic Approaches in Neurodegeneration; Part IV. Normal
neurodegeneration; 36. Potential role of MR spectroscopy, diffusion weighted/diffusion           Aging; Part V. Alzheimer’s Disease; Part VI. Other Dementias; Part VII. Parkinson’s and
tensor imaging and perfusion weighted imaging in traumatic brain injury: overview; 37. MR        Related Movement Disorders; Part VIII. Cerebellar Degenerations; Part IX. Motor Neuron
spectroscopy in traumatic brain injury; 38. Diffusion- and perfusion-weighted MR imaging in      Diseases; Part X. Other Neurodegenerative Diseases.
head injury; 39. Pediatrics: overview; 40. Physiological MR of normal development and            June 2005 1008pp 221 illustrations
developmental delay; 41. MR spectroscopy of hypoxic brain injury; 42. The role of diffusion      0 521 81166 X    Hardback        £220.00
and perfusion weighted brain imaging in neonatology; 43. Physiological MR of pediatric
brain tumors; 44. Physiological MRI techniques and pediatric stroke; 45. MR spectroscopy
in pediatric white matter disease; 46. MR spectroscopy of inborn errors of metabolism.              Special Introductory Price of £195.00
2004 852pp 485 illustrations                                                                        £220.00 after 31 August 2005
0 521 82457 5    Hardback                £185.00
     NEW EDITION                                                  The A-Z of                                                    The Circuitry of the
        TEXTBOOK                                                  Neurological Practice                                         Human Spinal Cord
                                                                  Roger A. Barker                                               Its Role in Motor Control and
                                                                  Cambridge Centre for Brain Repair
The Brain and Behavior                                                                                                          Movement Disorders
                                                                  Neil Scolding
                                                                  Frenchay Hospital, Bristol, UK                                Emmanuel Pierrot-Deseilligny
An Introduction to Behavioral                                                                                                   Groupe Hospitalier Pitié-Salpétrière, Paris, France
Neuroanatomy                                                      Dominic Rowe
                                                                  RNSH, New South Wales, Australia                              and David Burke
2nd edition                                                       Andrew J. Larner
                                                                                                                                University of Sydney, Australia
David Clark                                                       Walton Centre for Neurology/Neurosurgery, Liverpool, UK       This comprehensive reference surveys the literature
Ohio State University, USA                                                                                                      related to the control of spinal cord circuits in humans,
                                                                  A pocket-sized ready-reference to neurology, organised        showing how they can be studied, their role in normal
Nashaat Boutros                                                   from A to Z, the content consists of a series of entries,
Yale University, Connecticut, USA                                                                                               movement, and how they malfunction in disease states.
                                                                  each one describing, in a readable and accessible style, an   Chapters are highly illustrated and consistently organised,
and Mario Mendez                                                  aspect of neurology. Ranging from providing overviews of      reviewing, for each pathway, the experimental
University of California, Los Angeles, USA                        major groups of diseases (e.g. the                            background, methodology, organisation and control, role
This new edition builds on the success of the previous            dementias) to more detailed coverage of specific              during motor tasks, and changes in patients with CNS
edition and retains the core aim of providing an                  disease categories (e.g. Alzheimer’s disease). This will      lesions. Each chapter concludes with a helpful resume.
accessible introduction to behavioral neuroanatomy.               become an essential resource for all those undertaking        This will be essential reading for research workers and
The text is presented in a highly structured and organised        training in neurology, as well as providing a reference       clinicians involved in the study, treatment and
format to help the reader distinguish between issues of           sourcefor generalists looking for a readable synopsis of      rehabilitation of movement disorders.
anatomical, behavioural and physiological relevance.              neurological conditions.
Simplified and clear diagrams are provided throughout             Features
                                                                                                                                • Distils the lifetime experience of two
the chapters to illustrate key points. Case examples are          • Succinct and structured coverage of                           eminent clinician-investigators
explored to set the neuroanatomy in the context of                  neurology
                                                                                                                                • Contains detailed methodology and
clinical experience.                                              • Organised for ease of access and                              experimental results
Features                                                            navigation
                                                                                                                                • Highly illustrated with spinal circuit
• Easily accessible for students and clinicians                   2004 938pp                                                      diagrams
• Covers basic brain-behaviour anatomy                            0 521 62960 8         Paperback       £35.00                  Contents: 1. General methodology; 2. Monosynaptic Ia
• Integrates relevant vignettes that illustrate                                                                                 excitation and post-activation depression; 3. Muscle spindles
  the behavioural consequences of brain                                                                                         and fusimotor drive: microneurography and other techniques;
  lesions                                                                                                                       4. Recurrent inhibition; 5. Reciprocal Ia inhibition; 6. Ib
                                                                                                                                pathways; 7. Group Ii pathways; 8. Presynaptic inhibition of Ia
Contents: 1. Introduction; 2. Gross anatomy of the brain;                                                                       terminals; 9. Cutaneomuscular, withdrawal and flexor reflex
3. Histology; 4. Occipital and parietal lobes; 5. Temporal                                                                      afferent responses; 10. Propriospinal relay for descending
lobe-neocortical structures; 6. Frontal lobe; 7. Basal ganglia;                                                                 motor commands; 11. Involvement of spinal pathways in
8. Diencephalon: hypothalamus and epithalamus;                                                                                  different motor tasks; 12. The pathophysiology of spasticity
9. Diencephalon: thalamus; 10. Brainstem; 11. Limbic system:                                                                    and parkinsonian rigidity.
temporal lobe; 12. Limbic system: cingulate cortex; 13. Limbic
system: overview; 14. Interhemispheric connections and                                                                          July 2005 570pp 154 illustrations
laterality.                                                                                                                     0 521 82581 4    Hardback         £110.00
August 2005 300pp    103 illustrations
0 521 54984 1    Paperback        c. £35.00
0 521 84050 3    Hardback         c. £70.00
The Neuropathology                                               Neurocutaneous                                                   Tinnitus Retraining
of Dementia                                                      Disorders                                                        Therapy
Second edition                                                   Edited by E. Steve Roach                                         Implementing the
Edited by Margaret Esiri                                         Wake Forest University, North Carolina, USA
                                                                                                                                  Neurophysiological Model
University of Oxford, UK                                         and Van S. Miller
                                                                 University of Texas Southwestern Medical Center, Dallas, USA     Pawel J. Jastreboff
Virginia M. -Y. Lee                                                                                                               Emory University School of Medicine, USA
and John Q. Trojanowski                                          The neurocutaneous disorders comprise a group of                 and Jonathan W. P. Hazell
Both from University of Pennsylvania School of Medicine, USA     neurological syndromes featuring skin lesions and often          University College London Hospitals, UK
                                                                 eye lesions, central and peripheral nervous system tumors,
Completely rewritten and updated, this new edition is                                                                             Tinnitus and oversensitivity to sound affect a substantial
                                                                 brain malformations, mental retardation, and psychiatric
almost twice the size of its predecessor. Illustrated in                                                                          number of the population. Pawel Jastreboff’s discovery of
                                                                 syndromes or seizures. This book provides an
colour throughout, and with contributions from the                                                                                the mechanisms by which tinnitus and decreased sound
                                                                 authoritative, illustrated review of the recognition,
world’s leading authorities, it is the definitive reference                                                                       tolerance occur has led to a new and effective treatment,
                                                                 investigation, treatment and genetics of these disorders.
on the neuropathology of dementia. It gives practical                                                                             Tinnitus Retraining Therapy (TRT). Audiologists, ENT
guidance to pathologists, describes the contribution of          … This book will now be the reference text                       specialists, psychologists and counsellors worldwide
neuroimaging to diagnosis, and surveys the clinical              for neurocutaneous disorders … I would                           currently practise this technique, with very high success
features of dementia.                                            strongly recommend it as a ‘must’ for the                        rates. This book presents a definitive description and
‘… this is certainly a compulsory purchase                       libraries of all department of adult and                         justification for the Jastreboff neurophysiological model
for neuroscience centres. It deserves to live                    paediatric neurology, clinical genetics and                      of tinnitus, outlining the essentials of TRT, reviewing the
on into further editions whose evolution                         dermatology.’                                                    research literature, and providing an expert critique of
                                                                          JOURNAL OF NEUROLOGY, NEUROSURGERY                      other current therapeutic practices.
will map the rapid advances being made in
                                                                                                          AND PSYCHIATRY
many of the conditions covered within.’                                                                                           ‘This book provides a comprehensive guide
                                        NEURORADIOLOGY           Contents: 1. Introduction; 2. Genetics of neurocutaneous         to Tinnitus retraining therapy … Not only
                                                                 disorders; 3. Syndrome/clinical recognition;                     does this book give a very detailed
Contents: 1. Definition, clinical features and                   4. Neurofibromatosis type 1; 5. Neurofibromatosis type 2;
neuroanatomical basis of dementia; 2. Important anatomical       6. Tuberous sclerosis complex; 7. Von Hippel-Lindau disease;
                                                                                                                                  description of this type of therapy, it links
landmarks in the brain in dementia; 3. Practical approach to     8. Neurocutaneous melanosis; 9. Basal Cell Nevus symdrome;       the theory to clinical practice and offers
pathological diagnosis; 4. Morphometric methods and              10. Epidermal Nevus syndrome; 11. Multiple endocrine             practical advice for implementation … a
dementia; 5. Safety precautions in laboratories involved with    neoplasia type 2; 12. Ataxia-telangiectasia; 13. Incontinentia   text that is both rigorous and practical
dementia diagnosis and research; 6. Molecular diagnosis of       pigmenti; 14. Hypomelanosis of Ito; 15. Cowden disease;
dementia 7. Neuropathology of the aging brain;                   16. Pseudoxanthoma elasticum; 17. Ehlers–Danlos syndrome;
                                                                                                                                  … Very readable Good value for money.’
8. Neuroimaging Alzheimer’s disease; 9. Alzheimer’s disease;     18. Progeria; 19. Blue Rubber Bleb Nevussyndrome;                               BRITISH SOCIETY OF AUDIOLOGY NEWS
10. Down’s syndrome and Alzheimer’s disease; 11. Sporadic        20. Hereditary hemorrhagic telangiectasia (Osler-Weber-
tauopathies: Pick’s disease, corticobasal degeneration,                                                                           Contents: 1. Introduction; 2. The neurophysiological model
                                                                 Rendu); 21. Hereditary neurocutanous angiomatosis;
progressive supranuclear palsy and argyrophilic brain disease;                                                                    of tinnitus and decreased sound tolerance; 3. Tinnitus
                                                                 22. Cutaneous hemangiomas: vascular anomaly complex;
12. Hereditary tauopathies and idiopathic frontotemporal                                                                          retraining therapy – a clinical implementation of the model;
                                                                 23. Sturge–Weber syndrome; 24. Lesch–Nyhan syndrome;
dementias; 13. Vascular dementias; 14. Familial and sporadic                                                                      4. Evaluation of the treatment outcome and the results;
                                                                 25. Multiple carboxylase deficiency; 26.Homocystinuria due to
cerebral amyloid angiopathies associated with dementia and                                                                        5. Prevention; 6. Critical overview of the selected tinnitus
                                                                 cystathionine-synthase (CBS) deficiency; 27. Fucosidosis;
the BRI dementias; 15. Parkinson’s disease, dementia with                                                                         treatments; 7. Generalconclusions and future directions;
                                                                 28. Menkes Kinky Hair syndrome/Menkes disease;
Lewy bodies, multiple system atrophy and the spectrum of                                                                          Appendix; Index.
                                                                 29. Xeroderma pigmentosum, Cockayne syndrome and
diseases with alpha-synuclein inclusions; 16. Huntington         trichothiodystrophy; 30. Cerebrotendinous xanthomatosis;         2004 290pp 48 illustrations
disease; 17. Human prion diseases; 18. Alcoholism and            31. Adrenoleukodystrophy; 32. Peroximal disorders;               0 521 59256 9    Hardback               £40.00
dementia; 19. Hydrocephalus and dementia; 20. Head injury        33. Familial dysautonomia; 34. Fabry disease; 35. Giant
and dementia; 21. Infectious (and inflammatory) diseases         axonal neuropathy; 36. Chediak–Higashi syndrome;
causing dementia; 22. Schizophrenia and dementia; 23. Other      37.Encephalocraniocutaneous lipomatosis; 38.
diseases that cause dementia; 24. Transgenic mouse models        Cerebello–Trigemino–Dermal dysplasia; 39. Coffin–Siris
of neurodegenerative disease; Appendix: Dementia brain banks.    syndrome; 40. Lipoid proteinosis; 41. Macrodactyl-nerve
2004 584pp 269 illustrations                                     fibrolipoma.
0 521 81915 6    Hardback               £195.00                  2004 356pp 200 illustrations
                                                                 0 521 78153 1    Hardback               £125.00
Recovery after Stroke                                               Community                                                          Magnetic Resonance
Michael Barnes
Hunters Moor Regional Neurorehabilitation Centre,
                                                                    Rehabilitation                                                     Imaging in Stroke
                                                                                                                                       Edited by Stephen Davis
Newcastle Upon Tyne, UK                                             in Neurology                                                       Royal Melbourne Hospital and University of Melbourne,
Bruce Dobkin                                                        Michael P. Barnes                                                  Australia
University of California Los Angeles, USA                           and Harriet Radermacher
Julien Bogousslavsky                                                                                                                   Marc Fisher and Steven Warach
                                                                    Both from University of Newcastle upon Tyne, UK
                                                                                                                                       Both from National Institute of Health, Bethesda,
University of Lausanne, Switzerland
                                                                    This book analyses community rehabilitation needs from             Maryland, USA
A comprehensive guide to rehabilitation after stroke. It            many different perspectives, including the views of
                                                                                                                                       Advances in magnetic resonance imaging (MRI) are
sets out the basic neuroscientific principles that underlie         disabled people, rehabilitation clinicians and service
                                                                                                                                       transforming the investigation and treatment of
brain recovery and describes appropriate rehabilitation             providers. Many examples of community rehabilitation
                                                                                                                                       cerebrovascular disease. Echoplanar techniques with
strategies for the many different functional problems that          schemes are presented, with evidence for their
                                                                                                                                       diffusion and perfusion weighted imaging, together with
can arise after stroke.                                             effectiveness, and case studies are used to highlight the
                                                                                                                                       developments in magnetic resonance spectroscopy and
Features                                                            main issues.
                                                                                                                                       angiography, are replacing CT scanning as the diagnostic
• Most comprehensive guide available to                             Contents: 1. Background to community neurological                  modality of choice.
  rehabilitation after stroke                                       rehabilitation; 2. Neurological rehabilitation: basic principles
• Covers all the important post-stroke                              and models of delivery; 3. Models of disability; 4. Concepts       2003 280pp 127 illustrations
  syndromes, together with relevant basic                           of community; 5. The views of disabled people; 6. Outcome          0 521 80683 6    Hardback              £85.00
  neuroscience                                                      measures and research in the community; 7. Evidence base
                                                                    for community neurological rehabilitation; 8. Lessons from
• Written by world authorities, for the                             the South; 9. Other aspects of community neurological
  entire multidisciplinary rehabilitation team                      rehabilitation; 10. Community rehabilitation in childhood:
Contents: 1. Strokes: background/epidemiology/aetiology/            concepts to inform practice; 11. Neuropsychological
avoiding recurrence; 2. Principles of recovery after stroke;        rehabilitation in the community; 12. The way forward.                       FORTHCOMING
3. Regenerative ability in the central nervous system;
                                                                    2003 262pp 6 illustrations
4. Cerebral reorganisation after sensorimotor stroke;
5. Imaging brain in recovery after stroke; 6. Measurement in
                                                                    0 521 80874 X     Hardback                 £60.00
                                                                                                                                       Stroke Treatment and
stroke - disability and quality of life; 7. Evidence based stroke
rehabilitation; 8. Is early rehabilitation useful?; 9. Community
rehabilitation after stroke; 10. Physical therapy and               Upper Motor Neurone                                                Prevention
assessment; 11. Movement disorders after stroke; 12. Post-                                                                             An Evidence-based Approach
stroke spasticity and pain; 13. Sensory loss and proprioceptive     Syndrome and                                                       Graeme Hankey
rehabilitation; 14. Dysphagia; 15. Continence after stroke;
16. Sexual problems after stroke; 17. Rehabilitation of visual      Spasticity                                                         Royal Perth Hospital, Australia
disorders after stroke; 18. Dysphasia and dysarthria;                                                                                  This invaluable reference provides clinicians caring for
19. Cognitive problems after stroke; 20. Dementia after             Clinical Management and
                                                                                                                                       stroke patients with evidence for best practice in stroke
stroke; 21. Depression and fatigue after stroke; 22. Sleep          Neurophysiology                                                    treatment and secondary prevention. It describes all
disorders after stroke; 23. Assistive technology; 24. Vocational
rehabilitation; 25. A patient’s perspective.                        Edited by Michael P. Barnes                                        available treatments, and, where available, the highest
                                                                    and Garth R. Johnson                                               level of evidence for their safety and effectiveness. The
2005 668pp 43 illustrations
                                                                    Both from University of Newcastle upon Tyne, UK                    evidence for each treatment is followed by the author’s
0 521 82236 X    Hardback                 £95.00
                                                                    This is a thorough, practical reference and guide for all          interpretations, and the implications of the evidence in
                                                                    health professionals involved in the management of                 the care of stroke patients. This is therefore an essential
                                                                    spasticity.                                                        resource for clinicians, translating into practice advances
                                                                                                                                       that have been made in the treatment and prevention
                                                                     ‘… clear and clinically relevant … a good                         of stroke, and suggesting the most appropriate
                                                                    foundation for clinical practice …’.                               interventions.
                                                                                                 JOURNAL OF NEUROLOGY,
                                                                                                                                       Nov 2005 488pp 217 illustrations
                                                                                           NEUROSURGERY AND PSYCHIATRY                 0 521 82719 1   Hardback         c. £65.00
                                                                    2001 328pp 86 illustrations
                                                                    0 521 79427 7    Paperback                 £43.00
         FORTHCOMING                                        Plasticity in the                                                     THIRD EDITION
                                                            Human Nervous System
Textbook of Neural                                          Investigations with Transcranial                                   Diseases of the
Repair and                                                  Magnetic Stimulation                                               Nervous System
Rehabilitation                                              Edited by Simon Boniface
                                                            Addenbrooke’s Hospital, Cambridge, UK
                                                                                                                               Clinical Neuroscience and
Michael Selzer
                                                            and Ulf Ziemann
                                                                                                                               Therapeutic Principles
University of Pennsylvania, USA                                                                                                Edited by Arthur K. Asbury
                                                            Johann Wolfgang Goethe-Universität Frankfurt, Germany
Stephanie Clarke                                                                                                               University of Pennsylvania School of Medicine, USA
University of Lausanne, Switzerland                         Transcranial magnetic stimulation (TMS) is a non-invasive
                                                            and painless technique that has opened up completely
                                                                                                                               Guy M. McKhann
Leonardo Cohen                                                                                                                 The Johns Hopkins University School of Medicine,
                                                            new and fascinating avenues to study neural plasticity.
National Institute of Neurological Disorders and Stroke,                                                                       Baltimore, USA
                                                            Current knowledge of all these exciting possibilities is
MD, USA                                                                                                                        W. Ian McDonald
                                                            brought together in this book, written by the world’s
Pamela Duncan                                               leading experts in the disease.                                    University College London, UK
University of Florida, USA                                                                                                     Peter J. Goadsby
and Fred Gage                                               • Brings together two key areas in clinical                        University College London, UK
The Salk Institute, California, USA                           neuroscience, plasticity and TMS                                 and Justin C. McArthur
This unique reference, available individually or as a       • Contributors are world leaders in the field                      The Johns Hopkins University School of Medicine,
two-volume set, provides state-of-the-art coverage of       • Of essential interest to neuroscientists and                     Baltimore, USA
the rehabilitation of patients with neurological injury       clinicians                                                       The third edition of a neurology classic, this two-volume
and disease.                                                Contents: 1. The nature and mechanisms of plasticity;              comprehensive reference encompasses the basic neuro-
Volume I, Neural Repair and Plasticity, covers the          2. Techniques of transcranial magnetic stimulation;                science and clinical features of the full range of neurological
basic sciences relevant to the recovery of function         3. Developmental plasticity of the corticospinal system;
                                                                                                                               disorders, written by leading international experts in the
                                                            4. Practice induced plasticity in the human motor cortex;
following injury to the nervous system.                     5. Skill learning; 6.Stimulation induced plasticity in the human   field. Disease mechanisms are reviewed comprehensively,
Volume II, Medical Neurorehabilitation, covers              motor cortex; 7. Lesions of cortex and post-stroke                 with particular relevance to the principles of therapy.
the clinical information, authoritative guidelines, and     reorganisation; 8. Lesions of the periphery and the spinal         Sections cover the general principles of neurological
the rehabilitation approaches for all major categories of   cord; 9. Functional relevance of cortical plasticity;              disease, disorders of higher function, motor control, special
                                                            10. Therapeutic uses of rTMS; 11. Rehabilitation;                  senses, spine and spinal cord,bodily function, headache and
disabling neurological disorders.
                                                            12. New questions.
                                                                                                                               pain, neuromuscular disorders, epilepsy, cerebrovascular
                                                            2003 328pp 56 illustrations                                        disorders, neoplastic disorders, autoimmune disorders,
Volume I, Neural Repair and                                 0 521 80727 1    Hardback                £75.00                    disorders of myelin, infections, trauma and toxic disorders,
Plasticity                                                                                                                     degenerative disorders, and neurological manifestations
Nov 2005 500pp 96 illustrations                                                                                                of systemic conditions.
0 521 85641 8 Hardback          c. £90.00
                                                                                                                               ‘… a remarkable and successful effort to
Volume II, Medical                                                                                                             present in a comprehensive yet concise
                                                                                                                               manner a massive amount of data on
Neurorehabilitation                                                                                                            neurological diseases … the main value of
Nov 2005 500pp 152 illustrations                                                                                               this book for psychiatrists or neurologists
0 521 85342 6 Hardback           c. £90.00                                                                                     working with children resides in the superb
                                                                                                                               coverage of the general pathophysiological
2-Volume SET – save c.£40.00                                                                                                   and therapeutic aspects. Paediatric
Nov 2005 c. 1000pp 248 illustrations                                                                                           specialists will find in this book new
0 521 83639 5 Hardback            c. £150.00                                                                                   concepts and ideas about neurological
                                                                                                                               disorders that may be of value at any age,
                                                                                                                               allowing a better and more up-to-date
                                                                                                                               understanding of some of the conditions
                                                                                                                               they have to deal with.’
                                                                                                                                  EUROPEAN CHILD AND ADOLESCENT PSYCHIATRY

                                                                                                                               2002 2194pp 825 illustrations
                                                                                                                               0 521 79351 3   Hardback                £320.00
Women with Epilepsy                                              Childhood Epilepsy                                                The Neuropsychiatry
A Handbook of Health                                             Language, Learning and                                            of Epilepsy
and Treatment Issues                                             Behavioural Complications                                         Edited by Michael Trimble
Edited by Martha J. Morrell                                      William B. Svoboda                                                Institute of Neurology, London, UK
Columbia University, New York, USA                               Children with epilepsy often have interrelated language,          and Bettina Schmitz
and Kerry L. Flynn                                               learning and/or behavior complications which persist              Humboldt-Universität zu Berlin, Germany
Columbia-Presbyterian Cancer Center, New York, USA               beyond seizure control. In this comprehensive book,
                                                                                                                                   A multi-national team of experts to review and explore
                                                                 William Svoboda distils a lifetime of clinical experience
In this handbook for sufferers, their clinicians, families                                                                         the interface between epilepsy and behaviour disorders.
                                                                 into three areas which address the main points of
and friends, a team of experts reviews the special                                                                                 They begin by looking at how adequate existing
                                                                 difficulty, looking at why the problems arise and
problems faced by women with epilepsy. Hormone levels                                                                              classifications are for defining the subtleties of
                                                                 assessing treatments.
affect seizures and epilepsy treatments affect fertility, and                                                                      behavioural changes in patients with neurological
can cause pregnancy complications and birth defects.             Features                                                          disorders. Coverage is broad-ranging and offers both a
Many health-care providers are not informed about the            • Covers epilepsy in childhood specifically                       diagnostic and management perspective
unique issues facing women with epilepsy. This book,             • Looks at speech–language associations
published in association with the Epilepsy Foundation              with epilepsy                                                   ‘… this book serves to show the huge
of America, fills that gap and provides women with               • Looks at epileptic intrusions in behavior,                      possibilities for research in this fascinating
epilepsy with the information they need to be effective            language and learning as they impact on                         area of neurology, with implications for our
self-advocates.                                                    development and maturation                                      understanding of epilepsy and other
                                                                                                                                   affective disorders and better treatment
Features                                                         ‘… I recommend this book wholeheartedly
                                                                                                                                   of patients in the future.’
• Address the medical, emotional and social                      as a courageous undertaking, highlighting
                                                                                                                                                                                    THE LANCET
  challenges facing women with epilepsy                          problems that may go unrecognised long
• Written by a team of experts from the                          after the epilepsy has been brought under                         Contents: Part I. Background: 1. Introduction;
  epilepsy community                                             control.’                                                         2. Classification; 3. Limbic connectivity: anatomical substrates
• A comprehensive information resource,                                                                                            of behavioural disturbances in epilepsy; Part II. Clinical
                                                                                                                 THE LANCET
  written to be accessible to a lay-reader                                                                                         Aspects: 4. The psychiatry of idiopathic generalized epilepsy;
                                                                 Contents: Looking ahead; Part I. Speech and Language              5. Epilepsy and learning disorders; 6. Subtle cognitive and
‘The book is beautifully designed, printed,                      Problems: 2. Language, the challenge; 3. Speech, language         behavioural effects of epilepsy; 7. Aggression and epilepsy;
and produced … Women with Epilepsy                               and communication; 4. Speech and language problems in             8. Epilepsy and suicide; 9. Post-ictal psychoses revived; Part
                                                                 epilepsy; 5. Seizure types and language risks; 6. Language        III. Cognitive Aspects: 10. Dementia and epilepsy; 11. The risk
deserves the attention of the wide                               regressions with epilepsy syndromes; 7. Other epilepsy            of cognitive decline in patients with refractory temporal lobe
audience for whom it is written. Men with                        language syndromes; 8. Seizure management effects;                epilepsy; 12. Behavioural and neuropsychological aspects of
epilepsy need not feel neglected because                         9. Evaluation of speech and language problems;                    frontal lobe epilepsy; Part IV. Non Epileptic Attacks:
there is much content that is applicable to                      10. Management of speech and language problems in                 13. Seizures, epilepsy and dissociation; 14. Psychobiology of
                                                                 epilepsy; 11. Behavior consequences; Part II. Learning            psychogenic pseudoseizures; 15. Epilepsy and panic disorder;
their seizure-related problems.’                                 Problems: 12. Learning challenges; 13. The development of         Part V. Treatment Complications: 16. The effects of
                                                THE LANCET       learning; 14. Learning difficulties; 15. Learning problems with   antiepileptic drugs on behaviour; 17. Antiepileptic drug
                                                                 seizure types; 16. Modifying factors; 17. Transient cognitive     treatment and epileptic seizures: effects on cognitive function;
Contents: Part I. The Woman with Epilepsy; Part II. Epilepsy
                                                                 impairments of epilepsy; 18. Alertness and attention;             18. Psychiatric effects of surgery for temporal lobe epilepsy;
Diagnosis and Treatment; Part III. Hormones and the Brain;
                                                                 19. Memory; 20. Executive functioning; 21. Academics;             19. Vagus nerve stimulation and mood; Part VI. Treatment:
Part IV. Health Challenges for Women with Epilepsy; Part V.
                                                                 22. Antiepileptic medication effects; 23. Effects of other        20. On the use of psychotropic drugs in patients with seizure
Family Planning, Pregnancy and Parenting; Part VI. Living Well
                                                                 therapies; 24. Diagnosis; 25. Gaining help; 26. Frustrations of   disorder; 21. The role of psychotherapy in the treatment of
with Epilepsy.
                                                                 learning problems; Part III. Behavior Problems: 27. Mental        epilepsies; 22. Choosing measures to assess quality of life
2003 310pp 30 illustrations                                      health needs; 28. Psychologic development; 29. Seizure types      (QQL) in epilepsy.
0 521 65541 2    Paperback              £21.99                   and modifying factors; 30. Overview: extrinsic factors;
                                                                 31. Behavior problems, general; 32. Attention deficit disor-
                                                                                                                                   2002 360pp 70 illustrations
0 521 65224 3    Hardback               £60.00                                                                                     0 521 00516 7    Paperback               £49.95
                                                                 ders; 33. Anxiety disorders; 34. Mood disorders; 35. Disruptive
                                                                 behavior problems; 36. Psychoses of epilepsy; 37. Non-            0 521 81374 3    Hardback                £130.00
                                                                 epileptic events; 38. Possible treatment issues; 39. Helping
                                                                 with psychiatric problems.
                                                                 2004 672pp
                                                                 0 521 82338 2          Hardback         £85.00
Antiepileptic Drugs                                               Neurodevelopment                                                       The Self in
Combination Therapy                                               and Schizophrenia                                                      Neuroscience and
and Interactions                                                  Edited by Matcheri Keshavan
Edited by Jerzy Majkowski                                         University of Pittsburgh, USA
Foundation of Epileptology, Warsaw, Poland                        and James Kennedy                                                      Edited by Tilo Kircher
                                                                                                                                         Aachen Medizinische Universität, Germany
Blaise Bourgeois                                                  Clarke Institute of Psychiatry, Toronto, Canada
Yale University, Connecticut, USA                                 Robin Murray                                                           and Anthony David
                                                                                                                                         Institute of Psychiatry, London, UK
Philip Patsalos                                                   Institute of Psychiatry, London, UK
Institute of Neurology, London, UK                                                                                                       In recent years neuroscience has contributed important
                                                                  Over the past decade, developmental neurobiology has
and Richard Mattson                                                                                                                      insights to the concept and construction of the self
                                                                  made important strides towards elucidating the patho-
Harvard University, Massachusetts, USA                                                                                                   from conditions, such as schizophrenia, in which the
                                                                  physiology of psychiatric disorders. Nowhere has this link
                                                                                                                                         self becomes disordered. This book focuses on
This book reviews the use of antiepileptic drugs focussing        between basic science and clinical insights become clearer
                                                                                                                                         neuropsychiatric models of self-consciousness, set
on the interactions between these drugs and between               than in the field of schizophrenia research. In this volume,
                                                                                                                                         against introductory essays describing the philosophical,
antiepileptics/other drugs, which can be beneficial or            the editors bring together some of the most active
                                                                                                                                         historical and psychological approaches.
can cause harm. It aims to increase awareness of the              investigators in this field. Each contributor provides a
possible impact of combination therapies.                         state-of-the-art overview of the relevant research,                    Features
Pharmacokinetic/pharmacodynamic interactions are                  including directions for further investigation.                        • Encompass an extensive review of current
discussed supported by clinical/experimental data.                                                                                         scientific and clinical approaches to
                                                                                                                                           consciousness and self-consciousness
Features                                                          • Focuses on a serious and debilitating
                                                                                                                                         • Focuses on pathological states of
• Covers the benefits and pitfalls of                               condition
                                                                                                                                           self-consciousness, such as in schizophrenia
  combination therapy                                             • Extensively referenced                                                 and disordered mental states
• Describes mechanisms of interactions as                         • Of interest to researchers and clinicians
                                                                                                                                         Contents: Introduction: the self and neuroscience; Part A.
  well as clinical significance                                   Contents: 1. Genes and brain development; 2. Brain develop-            Conceptual Background: 1. The self and psychiatry;
• Contributions from an international team                        ment in healthy children and adolescents: magnetic resonance           2. The self in philosophy, neuroscience and psychiatry;
  of authors and editors                                          imaging studies; 3. Cognitive development: fMRI studies;               3. Phenomenology of self; 4. Language and self-consciousness;
                                                                  4. Cognitive development in adolescence: cerebral underpinnings,       Part B. Cognitive and Neurosciences: 5. Multiplicity of
Contents: 1. Combination therapy of diseases: general             neural trajectories and the impact of aberrations; 5. Brain            consciousness and the emergence of self; 6. Asynchrony;
concepts; 2. Combination therapy with antiepileptic drugs:        plasticity and long-term function after early cerebral insult: the     implicational meaning and the experience of self in
potential advantages and problems; 3. Pharmacogenetic             example of very preterm birth; 6. Do degenerative changes              schizophrenia; 7. Self-awareness, social intelligence and
aspects; 4. Pharmacokinetic principles and mechanisms of          operate across diagnostic boundaries? The case for                     schizophrenia; 8. The neural correlates of self-awareness and
drug interactions; 5. Predictability of metabolic antiepileptic   glucocorticoids involvement in major psychiatric disorders;            self-recognition; 9. Autonoëtic consciousness; 10. The neural
drug interactions; 6. Influence of food and drugs on the          7. Velo-cardio-facial syndrome (deletion 22q11.2): a homoge-           nature of the core self; Part C. Disturbances of the Self: The
bioavailability of antiepileptic drugs; 7. Interactions between   neous neurodevelopmental model for schizophrenia; 8. Can               Case of Schizophrenia i. Phenomenology: 11. Self and
antiepileptic drugs; 8. Interactions between antiepileptic and    structural MRI provide an alternative phenotype for genetic            schizophrenia: a neuropsychological perspective;
non-antiepileptic drugs; 9. Pharmacodynamic principles and        studies of schizophrenia?; 9. Nutritional factors and schizophrenia;   12. Schizophrenia, self-disturbance and the intentional arc;
mechanisms of drug interactions; 10. Methods for assessing        10. Schizophrenia, neurodevelopment, and epigenetics                   13. The self-experience of schizophrenics; ii. Social
pharmacodynamic interactions; 11. Experimental studies of         11. Early environmental risk factors for schizophrenia;                Psychology: 14. The paranoid self; 15. Schizophrenia and the
pharmacodynamic interactions; 12. Clinical studies of             12. Transcriptomes in schizophrenia: assessing altered gene            narrative self; 16. Self-narrative in schizophrenia; iii. Clinical
pharmacodynamic interactions; 13. Clinical studies of             expression with microarrays; 13. Is there a role for social factors    Neuroscience: 17. Schizophrenia as disturbance of the self
pharmacodynamic interactions between antiepileptic agents         in a comprehensive development model for schizophrenia?;               construct; 18. Action recognition in normal and schizophrenic
and other drugs; 14. Antiepileptic drug interactions in           14. How does drug abuse interact with familial and develop-            subjects; 19. Disorders of self-monitoring and the symptoms
children; 15. Antiepileptic drug interactions in the elderly;     mental factors in the aetiology of schizophrenia? 15.                  of schizophrenia; 20. Hearing voices or hearing the self in
16. Antiepileptic drug interactions in pregnancy;                 Developmental dysregulation of the dopamine system and the             disguise?; 21. The cognitive neuroscience of agency in
17. Antiepileptic drug interactions in handicapped and            pathophysiology of schizophrenia; 16. The development of               schizophrenia; 22. Self-consciousness: an integrative
mentally retarded patients; 18. Antiepileptic drugs and sex       ‘mis-wired’ limbic lobe circuitry in schizophrenia and bipolar         approach from philosophy, psychopathology and the
steroids; 19. Antiepileptic drug interactions in patients         disorder; 17. Development of thalamocortical circuitry and the         neurosciences.
requiring psychiatric drug treatment; 20. Antiepileptic drugs     pathophysiology of schizophrenia; 18. X chromosome, estrogen,
in non-epileptic health conditions – possible interactions;       and brain development, implications for schizophrenia;                 2003 496pp 35 illustrations
21. Drug monitoring in combination therapy; 22. Cognitive         19. Premorbid structural abnormalities in schizophrenia;               0 521 53350 3    Paperback                 £30.00
side-effects due to antiepileptic drug combinations and           20. Neurodegenerative models of schizophrenia; 21. Does dis-           0 521 80387 X    Hardback                  £80.00
interactions; 23. Selection of drug combinations in clinical      ordered brain development cut across diagnostic boundaries?;
practice – current and future perspectives; 24. Future research   22. Can one identify preschizophrenic children? 23. High risk
– an experimental perspective; 25. Future research – a clinical   studies, brain development and schizophrenia; 24. Developmental
perspective.                                                      models and hypotheses-driven early interventions in
June 2005 488pp 16 illustrations                                  schizophrenia.
0 521 82219 X   Hardback         £85.00                           2004 506pp 22 illustrations
                                                                  0 521 82331 5    Hardback                   £85.00
Catatonia                                                     Disorders of                                                  Prechtl’s
A Clinician’s Guide to                                        Brain and Mind                                                Method of
Diagnosis and Treatment                                       Volume 2
Max Fink                                                      Edited by Maria A. Ron
State University of New York, Stony Brook, USA                Institute of Neurology, London, UK                            General
and Michael Alan Taylor                                       and Trevor W. Robbins
Finch University of Health Sciences, Chicago, USA             University of Cambridge, UK                                   Movement Assessment
This book, by two leading neuropsychiatrists, describes                                                                     Christa Einspieler
                                                              The clinical and scientific scope of this authoritative new
the features of catatonia, teaches the reader how to                                                                        Medical University of Graz, Austria
                                                              book encompasses abnormal and normal mind imaging,
identify and treat the syndrome successfully, and             genes and behaviour, brain development, consciousness,        Heinz F. R. Prechtl
describes its neurobiology. Patient vignettes from the        aggression, dementia, affective illness, and drug use and     Rijksuniversiteit Groningen, The Netherlands
authors’ practices, and many from the classical literature,   abuse.                                                        Arend F. Bos
illustrate the principles of diagnosing and treating                                                                        Rijksuniversiteit Groningen, The Netherlands
patients with catatonia.                                      ‘The book illustrates the fascinating tools
                                                                                                                            Fabrizio Ferrari
Features                                                      neuroscience offers for the understanding                     Università degli Studi di Modena, Italy and Università di
• First book in English devoted to catatonia                  of brain disorders. It combines a sound                       Reggio Calabria, Italy
• Many clinical vignettes                                     introduction of new technologies with
                                                                                                                            and Giovanni Cioni
• Rating scales, tables and figures for easy                  applications to clinically relevant questions.
                                                                                                                            Università degli Studi, Pisa and Stella Maris Foundation, Italy
  reference                                                   This makes it an informative and inspiring
                                                              read for any scientist and student of                         Heinz Prechtl’s qualitative assessment of general
‘… an excellent book on catatonia. The                        neuroscience.’                                                movements (GMs) predicts cerebral palsy and
book is a very interesting and clinically                                 JOURNAL OF PSYCHOSOMATIC RESEARCH                 developmental deficits later on in life. It includes a
relevant review of the authors’ extensive                                                                                   CD-ROM giving 15 cases selected from the book to
experience in the research and treatment                      2003 492pp 40 illustrations                                   demonstrate the different age-specific movement patterns.
                                                              0 521 00456 X    Paperback             £50.00
of this neuropsychiatric illness … Authors                                                                                  Features
Fink and Taylor provide us with valuable                                                                                    • Gives a method for accurate, early
clinical experience and information for an                    Disorders of                                                     assessment of neural integrity
improved understanding and a more                                                                                           • Enables the early prediction of cerebral
effective treatment of this form of                           Brain and Mind                                                   palsy and other developmental deficits
psychosis.’                                                                                                                    later in life
                                                              Volume 1                                                      • A quick, non-intrusive and cost-effective
                             PSYCHOLOGICAL MEDICINE
                                                              Edited by Maria A. Ron                                           method
2003 274pp 33 illustrations                                   The National Hospital, London, UK                             Clinics in Developmental Medicine, 167
0 521 82226 2    Hardback              £60.00                 and Anthony S. David                                          2004 104pp 62 illustrations
                                                              Institute of Psychiatry, London, UK                           Hardback and CD ROM                      £30.00

                                                              ‘Most of the neuroscience that is relevant
                                                              to psychiatrists, or likely to be in the
                                                              foreseeable future, is here. The book
                                                              is particularly strong on cognitive
                                                              neuropsychology but also has many
                                                              excellent chapters on behavioural
                                                              pharmacology, neuroimaging and the
                                                              neurodevelopmental approach to
                                                              schizophrenia. … This is without doubt the
                                                              best introduction to neuroscience for
                                                                                    BRITISH JOURNAL OF PSYCHIATRY

                                                              1999 388pp 25 illustrations
                                                              0 521 77851 4    Paperback             £35.00

  SECOND EDITION                                              The Treatment                                                 Tuberous Sclerosis
                                                              of Gait                                                       Complex
Management of the                                             Problems in                                                   From Basic Science to Clinical
Motor Disorders                                               Cerebral Palsy                                                Phenotypes
                                                                                                                            Edited by Paolo Curatolo
of Children with                                              Edited by James R. Gage                                       Università degli Studi di Roma ‘Tor Vergata’, Italy
                                                              Gillette Children’s Speciality Healthcare, St Paul, USA
Cerebral Palsy                                                A range of experts who manage gait problems in cerebral
                                                                                                                            Tuberous sclerosis incorporates malformations
Edited by David Scrutton                                                                                                    characterized by disturbances in cellular differentiation
                                                              palsy have combined to create this state-of-the art           and growth. It presents with a complex association of
Institute of Child Health, University College, London, UK
                                                              resource. They examine brain pathology, current treatment     different neurological phenotypes, including seizures,
Diane Damiano                                                 modalities, child assessment, and treatment outcomes. An      cognitive impairments and autism. This book correlates
University of Washington, USA                                 attached CD-ROM illustrates the process of gait analysis.     new genetic data and basic science, covers clinical
and Margaret Mayston                                          Clinicians, therapists and bioengineers will find this book   presentation, reviews history and current diagnostic
University College London, UK                                 uniquely useful.                                              criteria, and deals with the recent advances in
This entirely rewritten new edition, with two new editors     Features                                                      neuropathology, molecular genetics and neurobiology
from America and Australia, describes the most up-to-         • Up-to-the-minute, comprehensive resource                    which give a better understanding of the pathogenesis
date thinking on the treatment of cerebral palsy.                for all the practitioners involved in gait                 of the disease.
Coverage includes the types of cerebral palsy; assessment;       management: from clinicians to
                                                                 bioengineers                                               ‘This is clearly the most authoritative and
goal-setting; learning and neural plasticity; mechanisms of
                                                              • Covers everything from brain pathology,                     contemporary statement of current
deformity, its prevention and treatment, and the transition
                                                                 computerized gait analysis and integrated                  knowledge yet published.’
to adult life.
                                                                 treatment methods to assessment of                                       FROM THE FOREWORD BY H . SARNAT
Features                                                         treatment outcomes
• Completely new book following on from                       • Includes CD-ROM showing pre- and post-                      Features
  and updating entirely the first edition of                     treatment examples, illustrating the                       • Comprehensive overview incorporating
  18 years ago                                                   process of gait analysis                                      the most up-to-date science
• Global in its view, with two new editors                    Clinics in Developmental Medicine 164                         • Enables better recognition, understanding
  covering the state of the art in America                                                                                     and diagnosis of a complex multisystem
  and Australia                                                2004 464pp 90 illustrations                                     disorder
                                                              1 898683 37 9 Hardback with CD              £85.00            • Covers clinical management, future and
‘… this will be an essential book for all                                                                                      current research, and most recent findings
those who are managing the health and                                                                                          from genetics and related fields
development of these children.’                                                                                             International Review of Child Neurology
                         NEW MEDICAL WORLD WEEKLY
                                                                                                                            2003 328pp 90 illustrations
Clinics in Developmental Medicine ,161                                                                                      1 898683 39 5    Hardback                £55.00
2004 214pp
1 898683 32 8         Hardback           £50.00
The Clinical                                                 Disorders of                                                         ALSO OF INTEREST
Management of                                                Neuronal Migration
Craniosynostosis                                             Edited by Peter G. Barth                                          Movement Disorders
                                                             Universiteit van Amsterdam, Netherlands
Edited by Richard Hayward
                                                             Disorders of neuronal migration are causes of mental
                                                                                                                               in Children
Barry Jones                                                  handicap, autism, and epilepsy. Many are genetically
                                                                                                                               Emilio Fernandez-Alvarez
David Dunaway                                                                                                                  Universitat de Barcelona, Spain
                                                             determined and need precise diagnosis to provide genetic
                                                             counselling. This book will help the clinician acquire            and Jean Aicardi
and Robert Evans
                                                             insight as well as proficiency in diagnosis.                      Hôpital Robert Debré,Paris, France
All from Great Ormond Street Hospital for Children,
London, UK                                                   Features                                                          This book brings the combined expertise of two
                                                             • Synthesises the accumulated knowledge                           world-known authorities to the systematic and practical
Children with craniosynostosis are born with
                                                               of a rapidly expanding, multi-disciplinary                      study of movement disorders in childhood. Clinical in
congenital deformities of the face and skull. In severe
                                                               field straddling pediatrics, neurology                          emphasis, the authors cover all the diseases, including the
cases associated problems are common: blindness,               and clinical genetics                                           less well-known conditions. For the first time all the
deafness, severe learning difficulties and facial
                                                             • Written by a team of well-known experts                         available information has been brought together in one
deformities. Outside specialized craniofacial units, there     in the field                                                    volume.
is nowhere for professionals involved in primary or          • Provides a comprehensive source of
secondary care to go for help with the many practical          information to aid in diagnosis and                             ‘There is still much to be learnt in the field
problems that these children present. In this book, a          counselling                                                     of paediatric movement disorder, and
distinguished team of editors have assembled experts in                                                                        much to be recorded in future texts in
the field to introduce the non-craniofacial specialist to    ‘This book is going to be a text of reference
                                                                                                                               the area. One can only hope that they
what can be achieved and how they can contribute to          for neurologists and epileptologists no
                                                                                                                               will be as intelligently written as this
the child’s welfare.                                         mater how many updated classifications of
                                                                                                                               pioneering work.’
Features                                                     malformations of cortical development may                            EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
• Written by practising specialists in                       arise.’
                                                                                  INFANT AND CHILD DEVELOPMENT                 International Review of Child Neurology
   craniosynostosis for non-specialists
• Shows non-specialists, from paediatricians                 International Review of Child Neurology                           2001 272pp 82 illustrations
   to speech therapists through                                                                                                1 898683 23 9    Hardback £50.00
   neurosurgery, ENT and opthamology,                        2003 220pp
   how they can help improve outcomes of                     1 898683 31 X         Hardback            £45.00
   afflicted children
• Accessible and practical enough for
   parents of affected children to find useful
Clinics in Developmental Medicine ,163
2004 438pp 70 illustrations                                    SECOND EDITION
1 898683 36 0    Hardback              £80.00
                                                             Diseases of the Nervous
                                                             System in Childhood
                                                             2nd edition
                                                             Jean Aicardi
                                                             Institute of Child Health, University College London, UK

                                                             This book is one of the best of its kind
                                                             and, as with the first edition, will
                                                             continue to take first place on the
                                                             bookshelf of all paediatric neurologists …’

                                                             Clinics in Developmental Medicine
                                                             1998 907pp 270 illustrations
                                                             1 898683 16 6    Hardback                 £165.00
Shaken Baby Syndrome                                             Cognitive and                                                          FORTHCOMING
and Other                                                        Behavioural
Non-Accidental Head                                              Disturbances of                                                      Central Nervous System
Injuries in Children                                             Epileptic Origin in                                                  Tumours of Childhood
                                                                                                                                      Edward Estlin
Edited by Robert Minns
University of Edinburgh, Scotland
                                                                 Children                                                             Royal Manchester Children’s Hospital, UK
                                                                 Edited by Thierry Deonna                                             and Stephen Lowis
and Keith Brown                                                                                                                       The Hospital for Sick Children, Bristol, UK
Royal Edinburgh Hospital for Sick Children, Scotland
                                                                 and Elaine Roulet-Perez
                                                                 Both from Université de Lausanne, Switzerland                        Ranging from epidemiology and neuroimaging through
The Research Programme on Shaken Baby Syndrome in                Preface by Jean Aicardi                                              the general principles of surgery and
Edinburgh is internationally recognised for its research         Institute of Child Health, University College London                 radiotherapy/chemotherapy to issues of palliative care and
into the impact and effects of shaking a baby. In this                                                                                quality of life, this concise, broad and practical text covers
book, a highly distinguished team of experts from the            This book describes the effects that different kinds of
                                                                                                                                      all clinical aspects of central nervous system tumours in
programme present their latest findings, covering                childhood epilepsy can have on the child's behavior and
                                                                                                                                      children. It provides an overview of current important
diagnosis and the resulting long-term disability.                cognitive development. The authors cover the evidence
                                                                                                                                      issues in diagnosis and management, and focuses on
                                                                 and the available diagnostic methods and therapies. The
Features                                                                                                                              important areas of research, with an emphasis on the
                                                                 book is written for the various professionals dealing with
• Based on the work of an internationally                                                                                             areas likely to impact on clinical practice. It will be essen-
                                                                 such children (pediatricians, neurologists, psychologists)
  recognised reseach programme                                                                                                        tial reading for all professionals involved in the care of
                                                                 and gives a general view of the complex interrelation
• Written by a team of experts with a                                                                                                 children with brain tumours.
                                                                 between medical psychological and educational problems
  wide range of clinical experience of the
  syndrome                                                       in these children.                                                   Features
• Essential reading for all clinicians treating                  Features                                                             • Concise, practical and accessible
  shaken baby syndrome in either hospital                        • Details the diagnostic methods of                                  • Fully up-to-date on developing areas of
  or community practice                                            neuropsychological testing                                           research and treatment, with an emphasis
                                                                                                                                        on areas likely to impact on clinical
Contents: 1. Epidemiology; 2. Mechanisms and clinical            • Includes case studies following children                             practice
presentation; 3. Haemorrhagic retinopathy of shaken injury:        over several years
clinical and pathological aspects; 4. Neuroimaging in acute
                                                                                                                                      • Provides a clear overview of current issues
                                                                 • Integrated approach to treatment,                                    in diagnosis and management
and subacute non-accidental head injury: ultrasound and            incorporating neurology, psychology and
CT; 5. Initial and sequential MRI in non-accidental injury;        educational interventions                                          Contents: Part I. Introduction to Paediatric CNS Tumours,
6. Skeletal injuries in non-accidental injury; 7. Secondary                                                                           and An Overview of Diagnosis, Biology and Therapy:
brain insult; 8. Early post-traumatic seizures; 9. Mechanism     Contents: Authors' appointments; Acknowledgements;                   1. Overview of CNS tumours in children; 2. Epidemiology of
and management of subdural haemorrhage;                          Preface; 1. Introduction; 2. Cognitive effects of epilepsy:          CNS tumours; 3. Neuro-imaging; 4. Pathology and molecular
10. Neurodevelopmental and neuropsychological outcome;           epilepsy as a non-paroxysmal disorder and the concept of             oncology; 5. Cell and tumour biology; 6. General principles of
11. Neuropathology of non-accidental head injury; 12. Child      'cognitive epilepsies'; 3. Epilepsy in the developing brain;         surgery; 7. General principles of radiotherapy; 8. General
protection and prevention; 13. Conclusions; Glossary of terms.   4. Epilepsy and cognitive functions: identifying the direct          principles of chemotherapy; Part II. CNS Tumours of
                                                                 effects of epilepsy; 5. Epilepsy and cognition functions: the        Childhood: 9. Low grade and high grade glioma;
Clinics in Developmental Medicine ,162                           other variables; 6. Cognitive and behavioural problems in            10. Ependymoma; 11. Brain stem glioma; 12. PNET;
Dec 2005 240pp 80 illustrations                                  childhood epilepsies: a literature review - what can it tell us      13. Germ cell tumours; 14. Choroid plexus tumours;
1 898683 35 2        Hardback            c. £50.00               about the direct role of epilepsy?; 7. Childhood neuropsychology     15. Craniopharyngioma; 16 Mixed neuronal tumours;
                                                                 (developmental cognitive neuropsychology) in the context of          17. Spinal cord tumours; 18. Secondary/metastatic tumours;
                                                                 epilepsy; 8. Epileptic cognitive dysfunction in specific epileptic   Part III. Late Effects, Rehabilitation and Palliative Care:
                                                                 syndromes or epileptic conditions; 9. Epileptic cognitive dys-       19. Late effects and quality of life; 20. Neuro-rehabilitation
                                                                 function in some specific brain pathologies; 10. Epilepsy surgery    and neuro-psychology; 21. Palliative care; Part IV. Summary
                                                                 in children: an opportunity to study the direct role of epilepsy     and Conclusion: 22. Summary and conclusions.
                                                                 in cognitive disturbances; 11. Epilepsy and mental retardation:
                                                                 the role of epilepsy; 12. Developmental disorders and epilepsy;      Clinics in Developmental Medicine 166
                                                                 13. Neuropsychological evaluation of cognitive-behavioural           Dec 2005 192pp 50 illustrations
                                                                 effects of epilepsy in children; 14. Practical clinical issues in    1 898683 38 7   Hardback        c. £50.00
                                                                 diagnosis and antiepileptic drug therapy; 15. Psychological
                                                                 and educational aspects: special implications for epilepsies
                                                                 with cognitive manifestations; 16. Adult outcome of childhood
                                                                 epilepsies with 'cognitive' epileptic manifestations: unexpected
                                                                 lessons from follow-up studies; 17. Conclusions or summary
                                                                 (for those who only read summaries); List of case studies.
                                                                 Clinics in Developmental Medicine, 168
                                                                 June 2005 250pp 72 illustrations
                                                                 1898683433      Hardback         c. £50.00
The International Journal of                                       Behavioural and                                        Palliative and
Neuropsychopharmacology                                            Cognitive Psychotherapy                                Supportive Care                                  

Journal of the International                                       Visual Neuroscience                                    Psychological Medicine
Neuropsychological Society                                          
                                                                   Clinics in Developmental                               International Journal of
Developmental Medicine                                             Medicine                                               Technology Assessment
and Child Neurology                                                           in Health Care                                                                              
                                                                   Cambridge Quarterly
Neuron Glia Biology                                                of Healthcare Ethics                       

Behavioral and Brain Science                                       International Psychogeriatrics                         For sample copies and ordering information for                                            Journals visit

                                                                                             Information is correct at time of going to press but is subject to change without notice.

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Printed in the United Kingdom at the University Press, Cambridge               May 2005

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