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Neurology _ Clinical Neuroscience


									Neurology &
Clinical Neuroscience
                       New Edition                                                                                   New in 2004

The Neuropathology of
Second Edition
Edited by Margaret Esiri
University of Oxford
Virginia M.-Y. Lee
and John Q. Trojanowski
both University of Pennsylvania School of Medicine
Completely rewritten and updated, this new
edition is almost twice the size of its
predecessor. Illustrated in colour through-
out, and with contributions from the world’s
leading authorities, it is the definitive
reference on the neuropathology of
dementia. It gives practical guidance to pathologists, describes the                                             The A-Z of Neurological
contribution of neuroimaging to diagnosis, and surveys the clinical features                                     Practice
of dementia.                                                                                                     Roger Barker       University of Cambridge
New material includes:                                                                                           Neil Scolding      Frenchay Hospital, UK
• Three entirely new chapters on neuroimaging, molecular diagnostics, and                                        Dominic Rowe       University of Sydney
transgenic models.                                                                                               Andrew J. Larner   Walton Centre for Neurology, UK
• Two chapters on tauopathies under new authorship.                                                              This is a pocket-sized ready-reference to
• A chapter under new authorship on synucleinopathies, which includes mul-                                       neurology. Organised from A to Z, the
tiple system atrophy.                                                                                            content consists of a series of entries, each
                                                                                                                 one describing, in a readable and accessible
From reviews of the first edition:                                                                                style, an aspect of neurology. This ranges
‘This up-to-date and authoritative account will be invaluable for practising                                     from providing overviews of major groups of
neuropathologists and a treasured work of reference for psychiatrists and                                        diseases (e.g. the dementias) to more detailed
neuroscientists with an interest in dementia.’                                                                   coverage of specific disease categories (e.g.
                     Nigel J. Cairns, International Journal of Geriatric Psychiatry                              Alzheimer’s disease). Specific neurological
‘ ... this publication is a ‘must have’ for every practising neuropathologist.’                                  conditions are described according to a very
                        Journal of Neuropathology and Experimental Neurology                                     structured template covering the definition
                                                                                                                 of the condition, its clinical features,
   CONTENTS                                                                                                      investigation, pathogenesis and treatment,
   Preface;1.Definition,clinical features and neuroanatomical basis of dementia;2.Important anatomical
   landmarks in the brain in dementia;3.Practical approach to pathological diagnosis;4.Morphometric
                                                                                                                 finishing with a small number of relevant and
   methods and dementia;5.Safety precautions in laboratories involved with dementia diagnosis and                up-to-date references. In addition, there are
   research;6.Molecular diagnosis of dementia;7.Neuropathology of the aging brain;8.Neuroimaging                 hints about differential diagnosis with
   Alzheimer’s disease;9.Alzheimer’s disease;10.Down’s syndrome and Alzheimer’s disease;11.Sporadic              extensive cross referencing between entries.
   tauopathies:Pick’s disease, corticobasal degeneration,progressive supranuclear palsy and argyrophilic brain
   disease;12.Hereditary tauopathies and idiopathic frontotemporal dementias;13. Vascular dementias;
                                                                                                                 This will become an essential resource for
   14. Familial and sporadic cerebral amyloid angiopathies associated with dementia and the BRI dementias;       those undertaking training in neurology, will
   15. Parkinson’s disease, dementia with Lewy bodies, multiple system atrophy and the spectrum of diseases      be of interest to those with interests closely
   with alpha-synuclein inclusions;16.Huntington disease;17.Human prion diseases;18.Alcoholism and               allied to neurology (e.g. neurosurgery,
   dementia;19.Hydrocephalus and dementia;20.Head injury and dementia;21.Infectious (and
   inflammatory) diseases causing dementia;22.Schizophrenia and dementia;23.Other diseases that cause
                                                                                                                 neurorehabilitation) as well as providing a
   dementia;24. Transgenic mouse models of neurodegenerative disease;Appendix:Dementia brain banks;              reference source for generalists looking for a
   Index.                                                                                                        readable synopsis of neurological conditions.
• International team of top-notch experts covering comprehensively all                                           • Succinct and structured coverage of
   aspects of the neuropathology of dementia                                                                       neurology
• Gives practical guidance for practising pathologists                                                           • Organised for ease of access and
2004 584pp              52 line diagrams 111 half-tones 106 colour figures
0 521 81915 6            Hardback           $699.00                                                              2004 186 x 123 mm 960pp
                                                                                                                 0 521 62960 8   Hardback                  $160.00
                                                               Plasticity in the Human
                                                               Nervous System
                                                               Investigations with Transcranial
                                                               Magnetic Stimulation
                                                               Edited by Simon Boniface
                                                               Addenbrooke's Hospital, Cambridge
                                                               Ulf Ziemann
                                                               Johann Wolfgang Goethe-Universität Frankfurt
                                                               Transcranial magnetic stimulation (TMS) is a non-
                                                               invasive and painless technique that has opened up
                                                               completely new and fascinating avenues to study
                                                               neural plasticity. First, TMS can be used to detect
                                                               changes in excitability or connectivity of the stimu-
                                                               lated cortex which may have occurred through
                                                               processes such as learning or recovery from a lesion. Second, repeated TMS by
Neurocutaneous Disorders                                       itself can induce changes in excitability and connectivity of the stimulated cor-
                                                               tex which may be used therapeutically in neurological and psychiatric disease.
Edited by E.Steve Roach                                        Third, TMS can induce short-lasting ‘virtual lesions’ which may directly test the
Wake Forest University, North Carolina
                                                               functional relevance of brain plasticity. Current knowledge of all these excit-
Van S. Miller
University of Texas Southwestern Medical Center, Dallas        ing possibilities is brought together in this book, written by the world’s lead-
The neurocutaneous disorders comprise a                        ing experts in the field.
large group of neurological syndromes that
                                                                  1. The nature and mechanisms of plasticity;2. Techniques of transcranial magnetic stimulation;
feature skin lesions and often eye lesions,                       3.Developmental plasticity of the corticospinal system;4.Practice induced plasticity in the human motor
central and peripheral nervous system                             cortex;5.Skill learning;6.Stimulation induced plasticity in the human motor cortex;7.Lesions of cortex and
tumors, brain malformations, mental                               post-stroke reorganisation;8.Lesions of the periphery and the spinal cord;9.Functional relevance of cortical
                                                                  plasticity;10. Therapeutic uses of rTMS;11.Rehabilitation;12.New questions.
retardation, psychiatric symptoms, or
seizures. Neurocutaneous syndromes have                        2003    328pp               47 line diagrams 7 half-tones 2 tables
been known for centuries, but recent                           0 521 80727 1              Hardback         $199.00
research into their cellular, biochemical and
molecular-genetic basis has pointed to an
essential need for a genotypic nosology. In
                                                               Neurodevelopment and
this book, a distinguished team of editors                     Schizophrenia
and authors provides an authoritative,                         Edited by Matcheri Keshavan
                                                               University of Pittsburgh
illustrated, up-to-the-minute review of the
current understanding of phenotype-                            James Kennedy
                                                               Clarke Institute of Psychiatry, Toronto
genotype relationships in these disorders,
                                                               Robin Murray
as well as their recognition, investigation                    Institute of Psychiatry, London
and treatment. It will be essential reading
                                                               Over the past decade, developmental neurobiology
for all neurologists as well as dermatolo-
                                                               has made important strides towards elucidating the
gists, geneticists and pediatricians.
                                                               pathophysiology of psychiatric disorders. Nowhere
                                                               has this link between basic science and clinical
‘The reader is most definitely in for a treat
                                                               insights become clearer than in the field of
… This edition of Neurocutaneous Disorders
                                                               schizophrenia research. In this volume, the editors
provides the essential and forward-looking
                                                               bring together some of the most active investigators
clinical and genetic data which points the
                                                               in this field. Each contributor provides a state-of-the-art overview of the
way to the future.’
                                                               relevant research, including directions for further investigation. The book
  From the foreword by Roger N. Rosenberg
                                                               begins with a section on advances in developmental neurobiology. This is
                                                               followed by sections on etiological and pathophysiological developments, and
• A uniquely authoritative overview of
                                                               models that integrate this knowledge. The final section addresses the clinical
  the clinical features, natural history
  and genetic and molecular mechanisms                         insights that emerge from the developmental models and sets the scene for
  of the neurocutaneous syndromes                              future efforts at early detection and prevention of schizophrenia. This book
• Highly illustrated throughout                                will be valuable to researchers in psychiatry and neurobiology, students in
                                                               psychology, and all mental health practitioners.
• Essential reading for both neurologists
  and dermatologists                                              CONTENTS
                                                                  Part I. The Developing Brain; PartII.Development and Psychopathology; Part III.Inegrative Models.
2004     356pp                                                 • Of interest to researchers and clinicians, extensively referenced
123 half-tones            7 figures          70 colour figures
0 521 78153 1             Hardback                 $399.00     • Focuses on a serious and debilitating condition
                                                               February 2005               520pp   17 tables 5 colour figures
                                                               0 521 82331 5              Hardback         $299.00
Community Rehabilitation in
Michael P. Barnes and Harriet Radermacher
University of Newcastle upon Tyne
Rehabilitation should not stop when the
disabled person is discharged from hospital, and
many neurological patients require ongoing
rehabilitation in order to maximise their
functional abilities, minimize complications and
promote full participation at home and in the
community. This book analyses community
rehabilitation needs from many different
perspectives, including the views of disabled
people, rehabilitation clinicians and service
providers. Many examples of community
rehabilitation schemes are presented, with evidence for their
effectiveness, and case studies are used to highlight the main issues. The                                Principles and Practice of
authors take an international view, and there are chapters dealing with
the disabled child in the community and with neuropsychological
                                                                                                          Emergency Neurology
rehabilitation. The first book to examine the growing trend towards                                        Edited by Sid M.Shah
                                                                                                          Michigan State University
community rehabilitation in neurology, it is directed towards all clinicians
involved with neurorehabilitation.                                                                        Kevin M. Kelly
                                                                                                          Drexel University, Philadelphia
   1.Background to community neurological rehabilitation;2.Neurological rehabilitation:basic principles   In this handbook, the emergency physician-
   and models of delivery;3.Models of disability;4.Concepts of community;5. The views of disabled         neurologist editorial team from the
   people;6.Outcome measures and research in the community;7.Evidence base for community                  acclaimed comprehensive text Emergency
   neurological rehabilitation;8.Lessons from the South;9.Other aspects of community neurological         Neurology bring its expertise to a readily
   rehabilitation;10.Community rehabilitation in childhood:concepts to inform practice;                   accessible reference tool for the emergency
   11.Neuropsychological rehabilitation in the community;12. The way forward.                             department. With a symptom-based
2003    262pp               6 tables                                                                      emphasis, the text, tables, and illustrations
0 521 80874 X              Hardback                $150.00                                                guide the emergency physician in the
                                                                                                          recognition, diagnosis, and management of
                           Forthcoming in 2005                                                            neurological disorders both common and
                                                                                                          complex. Integrating fundamental
Recovery after Stroke                                                                                     neurological concepts with the practical
                                                                                                          realities and demands of emergency care,
Edited by Michael Barnes
Hunters Moor Regional Neurorehabilitation Centre                                                          this handbook features management
                                                                                                          algorithms for dozens of conditions, and a
Bruce Dobkin
University of California                                                                                  list of ‘pearls and pitfalls’ at the conclusion
                                                                                                          of each of the 38 chapters. This survey of
Julien Bogousslavsky
University of Lausanne, Switzerland                                                                       best practices in emergency neurology
                                                                                                          provides succinct and crucial clinical
One third of people after stroke, having
                                                                                                          information for all emergency physicians
survived the first few weeks, return home with
                                                                                                          who diagnose and manage neurologic
significant residual disability, and can therefore
                                                                                                          disorders such as headache, seizure, and
benefit from an active, multidisciplinary
                                                                                                          spinal cord injury. Emphasizing efficient
rehabilitation programme. This is a
                                                                                                          neurological examination techniques, this is
comprehensive guide to rehabilitation after
                                                                                                          an essential handbook for emergency
stroke, in which leading international authorities
                                                                                                          physicians, internists, and residents.
set out the basic neuroscientific principles that underlie brain recovery,
including chapters on neural plasticity and neural imaging, and describe                                     CONTENTS
appropriate rehabilitation strategies for the many different functional                                      Part I.Neurological Examination and Neurodiagnostic Testing;
                                                                                                             Part II.Common Neurological Presentations; Part III.Specific
problems that can arise after stroke. These include movement disorders,
                                                                                                             Neurological Conditions: Part IV. Neurological Trauma;
sensory loss, dysphagia and dysarthria, problems with continence and                                         Part V. Pediatric Neurological Emergencies;
secual difficulties, and cognitive disorders. Also covered are measurement                                    Part VI.Pregnancy-Related Neurological Emergencies;
of disability and quality of life, assistive technology and vocational                                       Part VII.Neurotoxicology: Part VIII.Brain Death.
rehabilitation. It is therefore an essential handbook and reference for all                               • Applies fundamental principles of
members of the multidisciplinary stroke rehabilitation team, including                                      neurology to demands and constraints
medical personnel, therapists, clinical neuropsychologists and                                               of emergency neurology
rehabilitation nurses.
                                                                                                          • Symptom-based organization with
• Most comprehensive guide available to rehabilitation after stroke                                          extensive management algorithms,
• Covers all the important post-stroke syndromes, together with                                              treatment guidelines, illustrations, and
  relevant basic neuroscience                                                                                tables
• Written by world authorities, for the entire multidisciplinary                                          2004     454pp
  rehabilitation team                                                                                     60 line diagrams 40 half-tones 40 tables
June 2005     500pp    28 line diagrams 15 half-tones                                                     0 521 00980 4   Paperback        $140.00
0 521 82236 X    Hardback          $299.00
                                                           Women with Epilepsy
                                                           A Handbook of Health and
                                                           Treatment Issues
                                                           Edited by Martha J. Morrell
                                                           Columbia University, New York
                                                           Kerry L.Flynn
                                                           Columbia-Presbyterian Cancer Center, New York
                                                           In this handbook for sufferers, their clinicians,
                                                           families and friends, Martha Morrell assembles a
                                                           team of experts to review the special problems
                                                           faced by women with epilepsy. In many ways
                                                           epilepsy is a different disease in women than in
                                                           men, given the biological and gender differences
                                                           between the two. Epilepsy treatments affect fertility, and can cause
                                                           pregnancy complications and birth defects, but most of the available drugs
Childhood Epilepsy                                         have been tested on men. Moreover, hormone effects on seizures are of
                                                           particular concern to women at puberty, at menopause, and over the men-
Language, Learning and Behavioural                         strual cycle. Many health-care providers are not informed about the unique
Complications                                              issues facing women with epilepsy. This book, published in association with
William B. Svoboda                                         the Epilepsy Foundation of America, fills that gap and provides women with
More than half the numbers of children with                epilepsy with the information they need to be effective self-advocates.
epilepsy have interrelated language, learning                 CONTENTS
                                                              Part I. The Woman with Epilepsy:1.Introduction;2.Being a woman with epilepsy;3. The woman with
and/or behavior complications. By adulthood,                  epilepsy:a historical perspective;4.Quality of life issues for women with epilepsy; Part II.Epilepsy Diagnosis
these problems can interfere with                             and Treatment:5. The genetics of epilepsy;6.Antiepileptic drugs and other treatments for epilepsy;7.
socialization and employment. The seizures                    Epilepsy in children and adolescents;8.Non-epileptic seizures; Part III.Hormones and the Brain:9.Brain
may be controlled but the developmental                       differences between men and women;10.Sex hormones and how they act on the brain;11.Epilepsy and
                                                              the menstrual cycle;12.Menopause and epilepsy; Part IV. Health Challenges for Women with Epilepsy:
distortions can continue to present problems                  13.Reproductive health;14.Sexual dysfunction in epilepsy;15.Bone health in women with epilepsy;
for health and education systems and carers.                  16.Psychiatric complications in epilepsy; Part V. Family Planning,Pregnancy and Parenting:17. Family
In this comprehensive and fully referenced                    planning and contraceptive choice;18.Obstetrical health and risk of birth defects;19.Neurocognitive
book, William Svoboda distils a lifetime of                   outcome in children of mothers with epilepsy;20. Parents with epilepsy; Part VI.Living Well with Epilepsy:
                                                              21. The impact of epilepsy on relationships;22. Parenting the daughter with epilepsy;23.Safety issues for
clinical experience with childhood epilepsy                   women with epilepsy;24. Work issues;Appendix:the Epilepsy Foundation’s Campaign for Women’s Health;
into three areas which address each of the                    Index.
main areas of difficulty. In each he looks at
                                                           2003    310pp              9 half-tones 12 tables 9 figures
why the problems arise and assesses                        0 521 65541 2             Paperback                $69.95
diagnostic and remediative approaches. The
focus is on the whole care of the child rather
than on diagnosis, classification and                       The Neuropsychiatry of Epilepsy
medication alone. Clinicians, mental health                Edited by Michael Trimble
practitioners, educators and speech–language               Institute of Neurology, London
pathologists will find this book invaluable.                Bettina Schmitz
  CONTENTS                                                 Humboldt-Universität zu Berlin
  Preface;1.Looking ahead; Part I.Speech and Language      Michael Trimble and Bettina Schmitz have
  Problems: Part II.Learning Problems: Part III.Behavior   assembled a multi-national team of experts to
                                                           review the most recent findings and explore the
• Covers epilepsy in childhood specifically                 interface between epilepsy and behaviour
• Looks at speech–language associations                    disorders. They begin by looking at the
   with epilepsy                                           classifications available and examine how
• Looks at epileptic intrusions in behavior,               adequate they are for defining the subtleties of
   language and learning as they impact on                 behavioural changes in patients with neurological
   development and maturation
                                                           disorders. Coverage is broad-ranging, from related cognitive problems, the
2004    672pp                                              biological underpinnings and pseudoseizures, to clinical aspects and treat-
0 521 82338 2        Hardback                 $299.00      ment issues. There has been a great deal of research in this area over recent
                                                           years, but limited published reviews. This timely book covers the practical
                                                           implications of ongoing research, and offers both a diagnostic and manage-
                                                           ment perspective. It will be essential reading for all professionals engaged in
                                                           the treatment of epileptic patients.
                                                           2002    360pp              46 tables 24 figures
                                                           0 521 00516 7             Paperback                           $160.00
Physiological Magnetic
Resonance in Clinical
Edited by Jonathan Gillard,Adam Waldman
and Peter Barker
The physiological magnetic resonance
techniques of diffusion imaging, perfusion
imaging and spectroscopy offer insights into
brain structure, function and metabolism. Until
recently, they were mainly applied within the
realm of medical research, but with their
increasing availability on clinical MRI machines,
they are now coming into clinical practice for
the evaluation of neuropathology in individual patients. This book
provides the reader with a thorough treatment of the underlying physical
principles of each of these methods, as well as a comprehensive review of
                                                                                     Introduction to Functional
their clinical applications. Topics covered include single- and multiple-voxel       Magnetic Resonance Imaging
MRS techniques, MR perfusion based on both arterial spin labelling and               Principles and Techniques
dynamic bolus tracking approaches, and diffusion-weighted imaging,                   R. B. Buxton
including techniques for mapping brain white matter fiber bundles.                    In An Introduction to Functional Magnetic
Clinical applications are reviewed in depth for each technique, with case            Resonance Imaging, Richard Buxton, a lead-
reports included throughout the book. Attention is also drawn to possible            ing authority, provides an invaluable intro-
artifacts and pitfalls associated with these techniques.                             duction to how fMRI works, from basic prin-
• Comprehensive review of advanced MRI techniques and                                ciples and the underlying physics and physi-
  applications                                                                       ology, to newer techniques such as arterial
                                                                                     spin labeling and diffusion tensor imaging.
• Explains clinical applications                                                     The supplementary CD-ROM contains all the
• Case reports included throughout the book                                          figures from the book as PowerPoint files,
March 2005    752pp                                                                  together with movies of cross-sectional
0 521 82457 5  Hardback                            $650.00                           anatomical MR images and a library of all
                                                                                     the MR images used in the movies as individ-
                                                                                     ual Tiff files. These comprise the following
Magnetic Resonance Imaging                                                           sets: high resolution volume imaging sets in
                                                                                     three orientations; T1-weighted spin-echo
in Stroke                                                                            (transverse); T2-weighted spin-echo (trans-
Edited by Stephen Davis                                                              verse); and T1-weighted true inversion
Royal Melbourne Hospital and University of Melbourne                                 recovery (sagittal). As a supplement to the
Marc Fisher & Steven Warach                                                          book, and a resource for teachers and
National Institute of Health, Bethesda, Maryland                                     researchers, this combination of text and
Magnetic resonance imaging provides non-                                             dual platform CD is invaluable.
invasive information about the brain’s blood                                           CONTENTS
                                                                                       Introduction; Part I.An Overview of Functional Magnetic
flow, water movement and biochemical
                                                                                       Resonance Imaging: I A.Introduction to Functional
abnormalities following stroke, and advances in                                        Neuroimaging:1.Energy metabolism in the brain;2.Cerebral
magnetic resonance imaging (MRI) are                                                   blood flow;3.Brain activation;I B. Introduction to Functional
transforming the investigation and treatment                                           Magnetic Resonance Imaging:4.Nuclear magnetic resonance;
                                                                                       5.Magnetic resonance imaging;6.Imaging functional activity;
of cerebrovascular disease. Echoplanar techniques
                                                                                       Part II.Principles of Magnetic Resonance Imaging:
with diffusion and perfusion weighted imaging, together with                           II A. The Nature of the Magnetic Resonance Signal:7.Basic
developments in magnetic resonance spectroscopy and angiography, are                   physics of magnetism and NMR;8.Relaxation and contrast in
replacing CT scanning as the diagnostic modality of choice. In this                    MRI;9.Diffusion and the MR signal;II B. Magnetic Resonance
                                                                                       Imaging:10.Mapping the MR signal;11.MRI techniques;
profusely illustrated book world leaders in these technologies review the
                                                                                       12.Noise and artifacts in MR images; Part III.Principles of
scientific basis and clinical applications of MRI in stroke. It will appeal to a        Functional Magnetic Resonance Imaging:III A. Perfusion
broad readership including stroke physicians, neurologists, neurosurgeons,             Imaging:13.Principles of tracer kinetics;14.Contrast agent
rehabilitation specialists, and others with a clinical or research interest in         techniques;15.Arterial spin labeling techniques;III B. Blood
                                                                                       Oxygenation Level Dependent (BOLD) Imaging:16. The nature
cerebrovascular disease.
                                                                                       of the BOLD effect;17.Mapping brain activation with
• State of the art coverage of techniques that are revolutionising the                 BOLD-fMRI;18.Statistical analysis of BOLD data;
  way stroke is investigated                                                           19.Efficient design of BOLD experiments;
• Editors and contributors are world leaders                                           Appendix:the physics of NMR;Index;CD-ROM.

• Profusely illustrated                                                              2002 536pp 134 line diagrams 34 half-tones
                                                                                     0 521 00274 5  HB & CD ROM        $599.00
2003 280pp               21 line diagrams 76 half-tones 14 colour plates 16 tables
                                                                                     0 521 58113 3  Hardback           $350.00
0 521 80683 6            Hardback         $199.00
Child Neurology Titles from Mac Keith Press
                                                                      Stroke and Cerebrovascular Disease in Childhood
                                                                      Edited by Vijeya Ganesan and Fenella Kirkham
                                                                      The field of stroke and cerebrovascular disease in children is one in which
                                                                      there has been much recent research activity leading to new clinical
                                                                      perspectives. This book, for the first time, summarises the ‘state of the art’ in
                                                                      this field. A team of eminent clinicians, neurologists and researchers from
                                                                      Britain, Europe and Canada provide an up-to-the-minute account of all
                                                                      aspects of stroke and cerebrovascular disease in children, ranging from a
                                                                      historical perspective to future directions, through epidemiology, the latest
                                                                      neuroimaging techniques, neurodevelopment, co-morbidities, diagnosis and
                                                                      treatment. The authors’ practical approach to the clinical problems makes
                                                                      this essential reading for practising clinicians. It will also be of interest to
                                                                      researchers in the field.
                                                                        1.Historical perspective;2.Epidemiology;3.Development of the cerebral circulation;4.Neuroimaging:
                                                                        clinical aspects;5.Recent advances in MR imaging;6.Arterial Ischaemic stroke:clinical presentation and
 Shaken Baby Syndrome and                                               differential diagnosis:6.1 Anterior circulation stroke;6.2 Posterior circulation stroke;6.3 Overview of
                                                                        aetiology;6.4 Cerebrovascular disease in children with AIS;6.5 Moyamoya;6.6 Dissection;6.7 Cerebral
 Other Non-Accidental Head                                              vasculitis;6.8 ‘Transient cerebral arteriopathy’;7.Stroke in children with underlying illness:7.1 Sickle cell
 Injuries in Children                                                   disease;7.2 Cardiac disease;8.Risk Factors for Arteriopathy and Stroke:8.1 Haematological;8.2 Infection;
                                                                        8.3 Other risk factors;8.4 Diagnostic approach;8.5 Acute management;8.6 Recurrence and prophylaxis;
 Edited by Robert Minns and Keith Brown                                 8.7 Outcome and rehabilitation;8.8 Cognitive sequelae;9.Cerebral venous thrombosis;10.Haemorrhagic
 The Research Programme on Shaken Baby                                  stroke:10.1 Epidemiology and clinical presentation;10.2 Interventional Neuroradiology;10.3 Surgical
 Syndrome in Edinburgh is internationally                               treatment;10.4 Stereotactic radiosurgery;11.Neonatal stroke;12.Metabolic stroke;13.Hemiplegic
                                                                        migraine;14.Alternating hemiplegia;15.Sturge-Weber syndrome;16. Vein of Galen malformation;
 recognised for its prominent ongoing research                          17.Future directions;Index.
 into the epidemiology, bio-mechanics, primary
                                                                      • Synthesises the most recent research findings in one book
 and secondary brain insults, neuroradiological
                                                                      • Gives a practical approach to the clinical problems
 aspects, medical–social aspects, and
 neurodevelopmental and neuropsychometric                             June 2005     180pp
 sequelae of shaking a baby. In this book, a                          1 898683 34 4    Hardback                        $175.00
 highly distinguished team of experts from the
 programme present the clinician with the                             The Clinical Management of
 latest findings on the syndrome, covering the
 diagnosis of the syndrome itself and the
 long-term disability that results which, unlike                      Edited by Richard Hayward,Barry Jones, David Dunaway
 other forms of child abuse associated with                           and Robert Evans
 psychological scars, is also associated with a                       Children with craniosynostosis are born with
 high degree of life-long physical and                                congenital deformities of the face and skull. In
 intellectual disability. This will be invaluable                     severe cases associated problems are common.
 reading to all the professionals concerned                           The child who is not properly cared for can end up
 with diagnosing and treating the syndrome.                           blind, deaf and with severe learning difficulties.
   CONTENTS                                                           In addition, they may be left with unacceptable
   Preface Martin Bax;1.Epidemiology;2.Mechanisms and clinical        facial deformities. Outside specialized craniofacial
   presentation;3.Haemorrhagic retinopathy of shaken injury:          units, there is at present nowhere for those
   clinical and pathological aspects;4.Neuroimaging in acute and
                                                                      involved in primary or secondary care to go for
   subacute non-accidental head injury:ultrasound and CT;
   5.Initial and sequential MRI in non-accidental injury;6.Skeletal   help with the many practical problems that these children present. In this
   injuries in non-accidental injury;7.Secondary brain insults;       book, a distinguished team of editors have assembled experts in the field to
   8.Early post-traumatic seizures;9.Mechanism and manage-            introduce the non-craniofacial specialist to what can be achieved and how
   ment of subdural haemorrhage;10.Neurodevelopmental and
                                                                      they can contribute to the child’s welfare. It will be essential reading for
   neuropsychological outcome;11.Neuropathology of non-
   accidental head injury;12.Child protection and prevention;         paediatricians seeking practical information about the management of these
   13.Conclusions;Glossary of terms;Index.                            disorders, and for specialists in neurosurgery, ENT, ophthalmology, plastic
 • Based on the work of an internationally                            surgery, maxillo-facial surgery, orthodontics, psychology, genetics,
   recognised reseach programme                                       anaesthesia, audiology and speech therapy.
 • Written by a team of experts with a wide                             CONTENTS
                                                                        1. The growth of the skull and face;2. The classification and clinical diagnosis of craniosynostosis;3. The
   range of clinical experience of the                                  molecular genetics of craniosynostosis;4. The epidemiology and incidence of craniosynostosis;5. The
   syndrome                                                             ante-natal diagnosis of craniosynostosis;6.Imaging and craniosynostosis;7.Principles of management of
 • Essential reading for all clinicians treating                        the child with craniosynostosis;8.Management of raised ICP;9 Management of airway obstruction;
   shaken baby syndrome in either hospital                              10.Management of ophthalmological complications;11.Management of malocclusion and dental
   or community practice                                                complications;12.Psychological considerations;13.Neurological problems of children with craniosynostosis
                                                                        and the role of the paediatrician;14.Speech and language development;15.Hearing disorders;16. The
 March 2005 240pp   80 half-tones                                       management of feeding problems in children with complex craniosynostosis;17. The role of the clinical
 1 898683 35 2 Hardback         $175.00                                 nurse specialist;18.Anaesthesia and the child with craniosynostosis;19. The surgical management of the
                                                                        child with craniosynostosis;Index.
                                                                      2004    438pp          30 half-tones           20 tables       20 figures
                                                                      1 898683 36 0         Hardback                  $170.00
Prechtl's Method of Qualitative General
Movement Assessment
Christa Einspieler, Heinz F. R.Prechtl,Arend F. Bos, Fabrizio Ferrari and Giovanni Cioni
A quick, non-invasive, non-intrusive and cost-effective method with high
reliability and high validity is much in demand for the early detection of
neurological anomalies which point to cerebral palsy and developmental
deficits later on in life. Over his years as a distinguished developmental
neurologist, Heinz Prechtl has devised such a method; a qualitative
assessment of general movements (GMs) as a specific predictor for
neurological impairments. His method is described in this book. GMs form
part of a distinct pattern of movements in preterm babies, term newborns
and young infants. They are complex, frequent, and usually of sufficient
length. Changes in the normal quality of GMs are a reliable indicator of
brain dysfunction. Includes a CD-ROM giving 15 cases selected from the
book. Each is of about one minute in duration and demonstrates the
different age-specific movement patterns.                                                                   Management of the Motor
  Authors’ appointments;Introduction:how it all came about;1.Basic concepts of developmental
                                                                                                           Disorders of Children with
  neurology;2.What are spontaneous movements?;3.How to record and assess general movements?;               Cerebral Palsy
  4.What could interfere with the quality of movements?;5.How objective, reliable and valid is the
  general movement assessment?;6. The clinical application of the method;7.Quantitative assessment is      Second Edition
  an insensitive indicator of an impaired integrity of the nervous system;8.Brain ultrasound and general   Edited by David Scrutton,Diane Damiano
  movement assessment;9.Neurological examination and general movement assessment;10.What                   and Margaret Mayston
  other methods of general movement exist?;Epilogue;References;Index.                                      Since the first edition of this book was
• Gives a method for accurate, early assessment of neural integrity                                        published in 1984 the intensive debates
• Enables the early prediction of cerebral palsy and other                                                 about the ‘correct’ method of treatment for
  developmental deficits later in life                                                                      children with cerebral palsy have been
                                                                                                           resolved and it is now possible to describe
• A quick, non-intrusive and cost-effective method                                                         what is generally agreed to be the optimal
April 2005    180pp   6 tables 56 figures                                                                   approach. This entirely rewritten new
1 898683 40 9   Hardback         $175.00                                                                   edition describes the most up-to-date
                                                                                                           thinking, with two new editors from
                                                                                                           America and Australia reflecting the
Gross Motor Function Measure (GMFM-66 and                                                                  worldwide picture. Coverage includes the
GMFM-88) User's Manual                                                                                     coordination of care and the management
Dianne J. Russell, Peter L.Rosenbaum,Lisa M.Avery and Mary Lane                                            team; the types of cerebral palsy;
                                                                                                           assessment; goal-setting; learning and neural
The Gross Motor Function Measure (GMFM) is the first evaluative measure                                     plasticity; global therapeutic approaches as
of motor function designed for quantifying change in the gross motor                                       well as more focused (topical) therapies; the
abilities of children with cerebral palsy. The measure is widely used                                      mechanisms of deformity, its prevention and
internationally, and is now the standard outcome assessment tool for                                       treatment; and the transition to adult life.
clinical intervention in cerebral palsy. This new version (GMFM-66) is                                     This is a completely new book detailing the
completely revised, largely new, and has been improved through Rasch                                       advancement of the subject over the past
analysis. GMFM-66 transforms the standard GMFM into an interval                                            18 years.
measure; provides an ‘item map’ of the relative difficulty among items;                                       CONTENTS
                                                                                                             Foreword;1. The family’s needs:coordination of care and the
and includes a user-friendly, computer-assisted software program to aid in                                   management team;2. The types of cerebral palsy;
scoring and interpretation of GMFM data. This is included, with a printed                                    3.Multidisciplinary;4.Goal setting and outcome measures;
scoresheet, on a CD-ROM enclosed in the book. The expertise of the                                           5.Global therapeutic approaches and the evolving role of
authors comprises paediatrics, design, engineering and physiotherapy.                                        physical therapy;6.Learning and neural plasticity;7. Focussed
                                                                                                             therapeutic approaches;8.Mechanisms of deformity;9.
They have over years devised and run research at the CanChild Centre for                                     Prevention of deformity;10. Treatment and management of
Childhood Disability Research at McMaster University in Hamilton,                                            hypertonia;11. Transition to adulthood;12.Prospects for the
Canada.                                                                                                      future;Index.
• Completely revised and rewritten to be an interval rather than                                           • Completely new book following on
  ordinal measure                                                                                            from and updating entirely the first
• Software to aid scoring and interpretation included on a CD-ROM                                            edition of 18 years ago
• The international standard in measurement of the motor abilities of                                      • Global in its view, with two new editors
  children with cerebral palsy                                                                               covering the state of the art in America
                                                                                                             and Australia
2002    230pp           24 tables 15 figures 10 colour figures
1 898683 29 8          HB & CD ROM              $190.00                                                    2004    214pp
                                                                                                           1 898683 32 8           Hardback                    $170.00
also available
Gross Motor Function Measure (GMFM)
Self-Instructional Training CD-ROM
1 898683 30 1          CD ROM                   $140.00
Central Nervous System Tumours                                                            The New Brain Sciences
of Childhood                                                                              Perils and Prospects
Edward Estlin and Stephen Lowis                                                           Edited by Dai Rees and Steven Rose
Ranging from epidemiology and neuroimaging through the                                    The last 20 years have seen an
general principles of surgery and radiotherapy/chemo-                                     explosion of research and develop -
therapy to issues of palliative care and quality of life, this                            ment in the neurosciences. Indeed,
concise, broad-ranging and practical text covers all clinical                             some have called this first decade of
aspects of central nervous system tumours in children. It                                 the 21st century ‘the decade of the
provides an overview of current important issues in                                       mind’. An all-encompassing term, the
diagnosis and management, and focuses on important                                        neurosciences cover such fields as
areas of research, with an emphasis on the areas likely to                                biology, psychology, neurology, psychiatry and philosophy
impact on clinical practice. It will be essential reading for                             and include anatomy, physiology, molecular biology,
paediatric oncologists, medical and clinical oncologists,                                 genetics and behaviour. It is now a major industry with
neurosurgeons, and paediatricians involved in the care of                                 billions of dollars of funding invested from both public and
children with brain tumours, trainees in these and related                                private sectors. Huge progress has been made in our under-
specialties, specialist nurses and paramedical staff.                                     standing of the brain and its functions. However, with
  CONTENTS                                                                                progress comes controversy, responsibility and dilemma.
  Part I.Introduction to Paediatric CNS Tumours, and An Overview of Diagnosis,
  Biology and Therapy:1.Overview of CNS tumours in children;2.Epidemiology of             The New Brain Sciences: Perils and Prospects examines the
  CNS tumours;3 Neuro-imaging;4. Pathology and molecular oncology;5.Cell and              implications of recent discoveries in terms of our sense of
  tumour biology;6.General principles of surgery;7.General principles of                  individual responsibility and personhood. With contributing
  radiotherapy;8.General principles of chemotherapy; Part II.CNS Tumours of               chapters from respected and influential names in neuro-
  Childhood:9.Low grade and high grade glioma;10.Ependymoma;11.Brain stem
  glioma;12.PNET; 13.Germ cell tumours;14.Choroid plexus tumours;                         science, law, psychology, philosophy and sociology, The New
  15.Craniopharyngioma;16.Mixed neuronal tumours;17.Spinal cord tumours;                  Brain Sciences should kick-start a discussion of where
  18.Secondary/metastatic tumours; Part III.Late Effects, Rehabilitation and Palliative   neuroscience is headed.
  Care:19.Late effects and quality of life;20.Neuro-rehabilitation and neuro-               CONTENTS
  psychology;21. Palliative care; Part IV. Summary and Conclusion:22.Summary and            Part I.Introduction: The new brain sciences; Part II. Freedom to Change:1.Do we
  conclusions.                                                                              ever really act?;2. The definition of human nature;3.Consciousness and the limits
April 2005    192pp   20 half-tones 20 tables 10 figures                                     of neurobiology;4.Mind metaphors. Neurosciences and ethics;5.Genetic and
                                                                                            generic determinism.A new threat to free will?; Part III.Neuroscience and the Law:
1 898683 38 7   Hardback          $175.00
                                                                                            6.Human action,neuroscience and the law;7.Responsibility and the law;
                                                                                            8.Programmed or licensed to kill? The new biology of femicide;9.Genes,
The Treatment of                                                                            responsibility and the law; Part IV. Stewardship of the New Brain Sciences:10. The
                                                                                            neurosciences:the danger that we will think we have understood it all; 11.On
Gait Problems in                                                                            dissecting the genetic basis of behaviour and intelligence;12.Prospects and perils
Cerebral Palsy                                                                              of stem cell research:a brief guide to current science;13. The use of human
                                                                                            embryonic stem cells for research:an ethical evaluation;14. The Prozac story;
Edited by James R.Gage                                                                      15.Psychopharmacology at the interface between the market and the new biology;
Building on his earlier single-                                                             16.Education in the age of Ritalin; Part V. Conclusion;References;Biographies.
authored text, James Gage has                                                             April 2005    192pp   20 half-tones 20 tables 10 figures
recruited a team of experts from the                                                      0 521 53714 2   Paperback                 $75.00
range of disciplines involved in man-
aging gait problems in cerebral palsy
to make this book a state-of-the art
resource. They examine the way the brain controls locomo-
tion and the types of brain pathology present in cerebral
palsy. Current treatment modalities and treatments of spe-
cific gait problems are discussed in detail, including modern                                          
computerized gait analysis and methods of assessing the
child and evaluating treatment outcomes. An attached CD-
ROM gives pre- and post-treatment examples and illustrates                                 Available to order from:
visually the process of gait analysis. Clinicians, therapists
and bioengineers will find this a uniquely useful resource.
  Introduction; Part I.Clinical Background: Part II. Patient Assessment: Part III.Gait
  Pathology in Cerebral Palsy: Part IV. Treatment:Epilogue;Index;CD-ROM.
• Up-to-the-minute, comprehensive resource for all the
   practitioners involved in gait management: from
   clinicians to bioengineers
• Covers everything from brain pathology, computerized
   gait analysis and integrated treatment methods to
   assessment of treatment outcomes
• Includes CD-ROM showing pre- and post-treatment
   examples, illustrating the process of gait analysis
2004    464pp                                                                                             Prices are correct at time of printing but are
30 half-tones 10 colour plates                 50 colour figures                                                 subject to change without notice
1 898683 37 9   HB & CD ROM                               $250.00

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