Tel. _949_ 419-0288 Fax. _949_ 419-0294 email. sales_chromadex.com

Document Sample
Tel. _949_ 419-0288 Fax. _949_ 419-0294 email. sales_chromadex.com Powered By Docstoc
					                                                                                             3




Tel. (949) 419-0288   Fax. (949) 419-0294   email. sales@chromadex.com   www.chromadex.com
2




Table of Contents
Table of Contents                                                                 2
Introduction To ChromaDex™ Services                                               3
Contract Services General Info                                                    4
Analytical Resources                                                              9
A Look at the DSHEA Supplement Label                                              10
Using ChromaDex™ as your Quality Control Lab                                      11
Single Laboratory Validation Services                                             12
Physico Chemical                                                                  14
Example Analytical Reports                                                        15
   • HPTLC Report (ATR)                                                           16
   • Analytical Test Report (ATR)                                                 18
   • Analytical Result Sheet (ARS)                                                21
Microbiological Testing Services List                                             22
Bioluminex™                                                                       24
ChromaDex™ Contract Services List                                                 25
   • Amino Acids                                                                  41
   • Vitamins                                                                     42
   • Literature Search                                                            43
   • Bioassays                                                                    44
Sample Submission Form                                                            46
Terms and Conditions                                                              47




         Tel. (949) 419-0288   Fax. (949) 419-0294   email. sales@chromadex.com        www.chromadex.com
                                                                                                                                       3




                                                                                                                                           Introduction
8




                 www.chromadex.com




                                       Introduction




                                                                                                                                            Validation
                                         ChromaDex is the leading provider of high purity phytochemical reference standards and
                                         reference materials to the pharmaceutical, nutraceutical, dietary supplement, food and
                                         beverage, and cosmetic industries. Over the past five years, ChromaDex has built a world-
                                         class team of scientists, covering every aspect of natural products chemistry, in the quest
                                         of isolating compounds for our ChromaDex phytochemicals library.




                                                                                                                                           Example Reports
                                         ChromaDex has two laboratory facilities in the United States:

                                         1) ChromaDex Clearwater, Florida
                                         2) ChromaDex Boulder, Colorado
    ChromaDex Clearwater, Florida
                                         Between these two facilities, ChromaDex has all of the staff and equipment resources
                                         necessary to support ChromaDex’s research and manufacturing activities as well as
                                         provide a wide range of contract services for our clients.

                                         ChromaDex is pleased to offer a complete suite of contract services “from Biomass to
                                         Bottle”:

                                         1. Analysis
                                         2. Research
                                         3. Raw Material Selection




                                                                                                                                           Micro-Bio
                                         4. Isolation and Synthesis(mg to kg)
                                         5. Process Development
                                         6. Method Development
    ChromaDex Boulder, Colorado
                                         7. Validation
                                         8. Formulation Analysis
                                         9. Litigation Support
                                         10. Consultancy

                                         “From Biomass to Bottle”




                                                                                                                                           Service List
                                                                                                                                           Forms




         Tel. (949) 419-0288    Fax. (949) 419-0294          email. sales@chromadex.com              www.chromadex.com
                  4
Introduction

                                                                                                                                                                    9


                       Analysis
                                                                                                                   www.chromadex.com
                       The core expertise of ChromaDex Analytics is Contract Analysis. These Contract Services are ideal for companies, teams, and indi-
                       viduals requiring everything from single sample analysis to complex method development or validation projects.

                       Below are just a few of the areas within the range of contract services offered by ChromaDex Analytics:
Validation




                       Types of Analytical Services:
                              -    HPLC with UV, Diode Array, ELSD, RI, Fluorescent, or Mass Spec Detection
                              -    GC with FID or Mass Spec Detection
                              -    UV Spectrophotometric
                              -    FTIR
                              -    Karl Fischer Titration – For Water
                              -    TLC or HPTLC
                              -    NMR
                              -    Mass Spectroscopy
                              -    X-Ray Crystallography
Example Reports




                              -    Stability Studies

                       Types of Testing:                                                               Testing for:
                              -    Raw Materials: Botanicals, Extracts, Intermediates, API…..          -   Marker compounds (Single or Multiple compounds)
                              -    Raw Material Blends                                                 -   Active ingredients/compounds
                              -    Dietary Supplements                                                 -   Fingerprinting (Qualitative)
                              -    Foods and Beverages                                                 -   Adulteration
                              -    Cosmetics                                                           -   Compound Characterization
                              -    Pharmaceuticals
                              -    Finished Products: Tablets, Capsules, and Softgels
                              -    Impurity Profiling

                       For a complete list analysis services offered by ChromaDex or to inquire about a specific type of analysis you may require, please contact
                       our technical services team at 949-419-0288 or sales@chromadex.com.
Micro-Bio




                      Isolation (mg/kg)
                      Are you looking to develop a new botanical extract, natural product based drug, or phytochemical? Do you need larger quantities of
                      non-commercially available or proprietary compound for research, analytical development, pre-clinical, or clinical studies? CDXA has
                      extensive experience in isolation, semi-synthesis and synthesis of compounds from natural sources.

                      Whether you have your own process or if you want ChromaDex to develop the process for you, ChromaDex can handle all of your
Service List




                      milligram to kilogram compound needs.

                      Types of compounds we have worked with:
                          -       Saponins, Triterpenes, Triterpene Glycosides
                          -       Flavonoids and Flavonoid Glycosides
                          -       Carotenoids
                          -       Quassinoids and Alkaloids
                          -       Fatty acids
                          -       Phenolic acids                                                        Specialized Services:
                          -       Tannins                                                                     -   Fractionation
                          -       Quinones and Anthraquinones                                                 -   Extraction
                          -       Phytosterols and Steroid related structures                                 -   Isolation
                          -       Liminoids                                                                   -   Crystallization
                          -       Macrolides                                                                  -   Synthesis
                          -       Many others….                                                               -   Process Development
Forms




                          Tel. (949) 419-0288              Fax. (949) 419-0294          email. sales@chromadex.com            www.chromadex.com
                                                                                                                                               5




                                                                                                                                                   Introduction
10
     Formulation
     analysis
     ChromaDex helps customers develop efficacious and stable products. We advise on
                   www.chromadex.com
     novel extracts and combinations which enable clients to achieve the desired goals and
     outcomes for each product. ChromaDex Formulation Services are intended for individu-
     als and companies that are in the beginning stages of planning a product to place on the
     market as well as for existing products that lack a strong market presence.




                                                                                                                                                    Validation
     ChromaDex Formulation Services
         -    Dosage Form Specification Development
         -    Manufacturing Process Optimization
         -    Product Specification Development
         -    Content Uniformity Evaluation



                                                                                  Research
         -    Dissolution Testing
         -    Product/Compound Stability Assessment
         -    Bio-Availability Evaluation

                                                ChromaDex has a wide base of experience and expertise in the natural products area.




                                                                                                                                                   Example Reports
                                                Our base in isolation of reference standards and reference materials has led to the forma-
                                                tion of a world class team of Natural Product Chemists, Analytical Chemists and Phar-
                                                macognosists. The ChromaDex Analytics Contract Research Group can help customers
                                                with a wide range of challenges, from sourcing appropriate raw materials and identification
                                                of new compounds to process development for large scale manufacture. This Contract
                                                Research Service is ideal for any sized organization that wants to leverage the experience
                                                of our expert team to maximize efficiency and achieve faster time-to-market.

                                                               Types of Contract Research Offered by CDXA:
                                                                   - Literature Searches
                                                                   - Raw Material Selection: Plant and extract
                formulation




                                                                   - Analytical Chemistry Research
                                                                   - Analytical Method Development
                                                                   - Isolation of Compounds
                                                                   - Characterization of Compounds




                                                                                                                                                   Micro-Bio
                                                                   - Process Development (Milligrams to Kilograms)
                                                                   - Formulation Analysis
                                                                   - Regulatory Review
                                                                   - Assessment of Toxicity and Safety
                                                               “From Biomass to Bottle”, ChromaDex knows natural products.




                                              Method
                                              Development/                                                                                         Service List
                                              Implementation
                                                Analytical method development can be critical when working with natural products.
                                                Whether you are analyzing incoming raw materials, in-process samples, or finished dos-
                                                age forms, using an appropriate method of analysis can be crucial to getting the right qual-
                                                ity control data. ChromaDex has extensive analytical method development experience
                                                “From Biomass to Bottle”. New methods can be developed for a wide range of sample
                                                types, using any of the equipment in our laboratories. For a complete list of equipment
                                                capabilities, please refer to the Analytical Resources section of this brochure.
                                                                                                                                                   Forms




             Tel. (949) 419-0288       Fax. (949) 419-0294           email. sales@chromadex.com              www.chromadex.com
                  6
Introduction

                                                                                                                                                                 11


                      raw
                      materials                                                                                        www.chromadex.com
Validation




                      Raw Material Selection
                      Whether you are trying to manufacture a botanical extract or an active pharmaceutical ingredient starting with plant biomass, the single
                      most important step will always be selecting the right biomass. The real intellectual property in developing natural based products or
                      drugs lies in the plant. ChromaDex has been working with biomass suppliers all over the world for many years in the quest to isolate
                      reference standards and reference materials. ChromaDex knows what to look for when it comes to quality of plant biomass. Raw
                      Material Selection Services are ideal for customers who have limited access to raw material resources or do not have the capabilities
Example Reports




                      to thoroughly validate material obtained from those suppliers.

                      ChromaDex Raw Material Selection Services:
                          -   Plant/Biomass Selection
                          -   Plant Species (including search for alternates)
                          -   Plant Part Selection (Root, rhizome, leave, whole plant…)
                          -   Harvest Time, Drying and Milling
                          -   Analytical Method Development (HPLC, GC, TLC…)
                          -   Extract Process Development (See Process Development)
                          -   Botanical Extract Selection




                      Process Development
Micro-Bio




                      Once you have selected your biomass and completed your research, now it’s time to scale up. CDXA works in all phases of project
                      development, from process concept to full-scale production. This includes process research and innovation, scale-up, design, con-
                      struction, operation of pilot plant or laboratory units, technology transfer, and optimization of manufacturing processes.

                      Process Development:
                          -   Analytical Development (Pre-process)
                          -   Process Research (milligrams and grams)
                          -   Process Development
                          -   Process Scale-up (grams to kilograms)
                          -   Research Evaluation and Coordination
                          -   Capital and Operating Cost Evaluation
Service List




                          -   Cost-Benefit Analysis
                          -   Project Management and Process Engineering
                          -   Detail Design
                          -   Process Transfer

                      ChromaDex has performed process development projects for:
                          - Dietary Supplement Ingredients: Extraction and Purification
                          - Cosmetic Ingredients: Extraction and Purification
                          - Pharmaceutical Ingredients: Extraction, Purification and Synthesis

                      Teamed with our customers and other project partners, we refine processes to make them financially attractive and commercially
                      successful. Our process development team also taps into ChromaDex’s industry experts as well as outside technical resources like
                      universities, government and private research organizations, and equipment vendors.
                      The real value for clients is in increased rate of innovation and reduced time-to-market for new products and processes. By working
Forms




                      closely with the scientific, engineering, and business staff of its clients, CDXA builds a seamless project team, acting as an extension
                      of the client’s own R&D capabilities.



                              Tel. (949) 419-0288         Fax. (949) 419-0294             email. sales@chromadex.com            www.chromadex.com
                                                                                                                                       7




                                                                                                                                           Introduction
12

     consultancy
                   www.chromadex.com




                                                                                                                                            Validation
                                Litigation Support
                                          Whether you are making a dietary supplement or a pharmaceutical, almost any scientific
                                          process or product needs to be assessed for legal ramifications. ChromaDex can offer
                                          true end-to-end analytical services to both protect against litigation as well as support
                                          companies during litigation. ChromaDex has the most sophisticated analytical equipment
                                          available for supporting legal issues.




                                                                                                                                           Example Reports
                                          ChromaDex has performed litigation support such as:
                                              -   Mediation where Analysis is Questioned
                                              -   Product Adulteration
                                              -   Prop 65 Claims
                                              -   Expert Witness for Analytical Issues
                                              -   Raw Material Disputes
                                              -   Patent Infringement




                                          Consultancy


                                                                                                                                           Micro-Bio
                                          Product Development is not just a science, it’s an art. Starting with an idea and getting
                                          to the finished product requires extensive planning, testing, and validation. ChromaDex
                                          Consultancy gives your company the best intelligence, analytical methods, marketing re-
                                          sources and litigation services available.

                                          Whether you are assessing your marketing position and materials, developing or investing
                                          in a new product, implementing GMPs, or restructuring your company, ChromaDex Con-
                                          sultancy can support your needs at every phase of product life cycle.

                                          ChromaDex Consultancy Specialties
                                              -   Product/Marketing Solutions for the US or International Markets
                                              -   Qualifying and Assessing Labeling and Advertising Claims



                                                                                                                                           Service List
                                              -   Ensuring Compliance with Regulatory Requirements
                                              -   Determining and Establishing Best-fit Business Practices
                                              -   Defining Regulatory Meaning and Impact
                                              -   Providing Regulatory Response and Potential Change Strategies
                                              -   Competitive Analysis and Market Assessment
                                              -   Infrastructure Analysis and Operations Assessment

                                          ChromaDex Consultancy offers a complete package of solutions for your business needs.
                                          While the focus of the consulting service is from a regulatory perspective, our goal is to
                                          maximize the impact of your product and company on the marketplace. Expert advice,
                                          guidance and strategic applications are tailored to help you achieve your business goals
                                          and benchmark new company successes. ChromaDex Consultancy enables you to iden-
                                          tify potential opportunities and act on them while moving your business forward through
                                          this highly competitive and regulated industry.
                                                                                                                                           Forms




        Tel. (949) 419-0288       Fax. (949) 419-0294           email. sales@chromadex.com            www.chromadex.com
                  8
Introduction



                                                                                                                                                  13




                                                                                                                        www.chromadex.com
Validation




                                                                                                                                  validation
Example Reports




                      Validation
                      No matter how well a developed method is intended to perform, analysts need to confirm
                      whether or not the method works when applied in the quality control environment. Ana-
                      lytical method validation shows that an analytical method is able to accurately determine
                      the level(s) of analytes of interest in a specified matrix. Validation of method for complex
Micro-Bio




                      matrices, like dietary supplements or plant-based extracts, can be very challenging. Chro-
                      maDex Method Validation Services are designed for companies who want their method
                      fully or partially validated, according to specific parameters defined for the method and
                      matrix.

                      ChromaDex Method Validation Services
                          - Full Validation
                          - Partial Validation
                          - Cross Validation

                      Fundamental Parameters for Method Development
                          -   Accuracy
Service List




                          -   Precision
                          -   Selectivity
                          -   Linearity
                          -   Limit of Detection(LOD)/Limit of Quantitation
                          -   Ruggedness
                          -   Robustness

                      Full Validation
                      Full method validation services are designed to cover the complete range of Validation
                      Parameters, as above. Full validation services can be tailored to suit each individual client’s
                      needs, ranging from Single Laboratory to Multi-Laboratory validation

                      Partial Validation
                      Partial method validation services are designed to monitor only a few of the validation
Forms




                      parameters, which may be crucial to the performance of the method. Partial validation can
                      also be performed in a single or multi-laboratory environment.


                              Tel. (949) 419-0288           Fax. (949) 419-0294            email. sales@chromadex.com         www.chromadex.com
                                                                                                                                 9




                                                                                                                                     Introduction
14




             www.chromadex.com


            Analytical Resources   GC (Gas Chromatography)
                                   1. Two HP 5890 Series II, plus GOs with auto samplers, split/splitteless, injector, FID and
                                   GC (Gas Chromatography)




                                                                                                                                      Validation
                                   1.   TCD.
                                        Two HP 5890 series II, plus GCs with auto samplers, split/splitless, injector, FID and
                                   2.   Agilent
                                        TCD. 6890 GC with autosampler, split/splitless, FID, and Agilent 5973 Mass Selective
                                   2.   Detector.
                                        Agilent 6890 GC with autosampler, split/splitless, FID, and Agilent 5973 Mass
                                        Selective Detector.
                                   MS (Mass Spectrometry)
                                   MS (Mass Spectrometry)
                                   1. Finnigan Navigator single quad with APCI and ESI ion sources.
                                   1. Finnigan API 3 Plus Triple Quad with APCI ion ESI ion
                                   2. PE SciexLCQ Deca ion trap with APCI and ESIand sources.sources
                                   2. Finnigan Navigator single quad with APCI and ESI ion sources.
                                   3. Finnigan LCQ Deca ion trap with APCI and ESI ion sources.
                                   HPLC (High Performance Liquid Chromatography)




                                                                                                                                     Example Reports
                                   1.   Twelve Agilent 1100 with quaternary pumps, autosamplers (six), variable wavelength
                                      detectors (four), fluorescence detector Liquid Chromatography)
                                    HPLC (High Performance (one) and ELSD (one).
                                   1. TSP/SP AS1000 (with autosampler, variable wavelength detector, SpectroFocus detector,
                                   2. Twelve Agilent 1100 with quaternary pumps, autosamplers (six), 96-well-plate
                                      autosamplers (four), diode array detectors (six), variable wavelength detectors (four),
                                      forward optical scanning detector, UV detector)
                                   3. and fluorescence detector (one).
                                      Three Dionex HPLC (with Autosampler, UV detector)
                                   2. TSP/SP AS1000 (with autosampler, variable wavelength detector, SpectroFocus
                                      detector, forward optical scanning detector, UV detector)
                                   HPTLC (High Performance Thin Layer Chromatography)
                                   1. Two CAMAG automatic TLC samplers
                                   Prep Scale Fluorchem 8900
                                   2. Alpha Innotech Chromatography
                                   1.
                                      CAMAG Built Carver’ Prep Scale Chromatography Unit
                                   3. Custom Scanner
                                   2. Waters Prep LC 2000 with 490E programmable multi-wavelength detector and
                                   4. ADC 3 cooled CCD cameras
                                      Gilson 206 fraction collector.
                                   5. Bioluminizer
                                   3. Septech ST500 with variable wavelength monitor and GP-900 controller.
                                   4. Merck Novaprep 5000 integrated prep scale HPLC
                                   Prep Scale Chromatography




                                                                                                                                     Micro-Bio
                                   1. Custom Built Carver Prep Scale Chromatography Unit
                                   Miscellaneous
                                   1. Waters Prep LC 2000 with 490E programmable with Sampletek automated Gilson 206
                                   2. Two Camile Clark Automated Glass Reactorsmulti-wavelength detector andsampling
                                       fraction collector.
                                       units (250 mL and 1L).
                                   2. Septech ST500 with variable wavelength monitor and GP-900 controller.
                                   3. PAR Hydrogenator high pressure reaction system (automated stirrer, temperature
                                       Merck Novaprep 5000 integrated prep scale HPLC
                                   4. and pressure control).
                                   3. Podbielniak centrifugal counter-current liquid/ liquid extractor.
                                   Miscellaneous
                                   4. PerkinElmer Paragon 500, FTIR Spectrometer
                                   5. Two Camile Clark Automated Glass Reactors with Sampletek automated sampling units (250
                                   1. Genevac HT-4 Centrifugal Evaporator.
                                   6. Three Hotpack stability chambers.
                                       mL and 1L).
                                   7. PAR Hydrogenator high pressure reaction system (automated stirrer, temperature and
                                   2. Fitzmill hammermill and UDY Cyclone sample mill.
                                   8. Multiple microbalances and analytical balances.
                                       pressure control).
                                   9. Podbielniak centrifugal counter-current liquid/liquid extractor.
                                   3. Three 20L Buchi rotovaps.



                                                                                                                                     Service List
                                   10. PerkinElmer Paragon 500,
                                   4. Ten 2L Buchi rotovaps. FTIR Spectrometer
                                   11. Genevac HT-4 Karl Fischer titrators
                                   5. One AquaStarCentrifugal Evaporator. & ovens.
                                   12. Three Hotpack stability chambers.
                                   6. Denver Instrument IR-200 moisture analyzer.
                                   13. Fitzmill hammermill and UDY Cyclone sample mill.
                                   7. Cary 50 Bio UV - Visible spectrophotometer.
                                   8. Multiple microbalances and analytical balances.
                                   9. Three 20L Buchi rotovaps.
                                   10. Ten 2L Buchi rotovaps.
                                   11. One AquaStar Karl Fischer titrators & ovens.
                                   12. Denver Instrument IR-200 moisture analyzer.
                                   13. Cary 50 Bio UV - Visible spectrophotometer.
                                                                                                                                     Forms




     Tel. (949) 419-0288    Fax. (949) 419-0294           email. sales@chromadex.com                www.chromadex.com
                  10
Introduction
Validation
Example Reports
Micro-Bio
Service List
Forms




                       Tel. (949) 419-0288   Fax. (949) 419-0294   email. sales@chromadex.com   www.chromadex.com
                                                                                             11




                                                                                                  Introduction
                                                                                                   Validation
                                                                                                  Example Reports
                                                                                                  Micro-Bio
                                                                                                  Service List
                                                                                                  Forms




Tel. (949) 419-0288   Fax. (949) 419-0294   email. sales@chromadex.com   www.chromadex.com
                  12
Introduction




                                            y
                  ChromaDex Single Laboratory Validation Services
Validation




                       TIME REQUIRED:           2 to 3 weeks (Not including optimization)

                       ESTIMATED BUDGET:                $15,000-$20,000 (Not including optimization)

                       Budget Notes:         The final budget cost will vary depending on the number of samples and sample
                       types submitted for validation. The budget may also vary depending on the method of analysis.

                       Single Laboratory Validation Protocol Following AOAC Guidelines degree of optimization
                       required (For Analytical Chemistry Methods)
Example Reports




                       Purpose:
                       1. Provide guidance to method submitters on the criteria to be used for accepting the method as an SLV method.
                       2. To provide uniformity in the review of methods submitted.
                       3. To assist in single lab validation in understanding the types of information the AOAC requires.

                       SLV Criteria:
                       1. Is the method clearly and understandably written? (Where alternatives are permitted, are the circumstances for each
                       option clearly and explicitly defined?)

                       2. Is the scope and applicability clearly stated? Methods submitted to the Dietary Substances Project must be
                       applicable to one or more of the following matrices or commercial products:
Micro-Bio




                               2.1 The parent botanical (vouchered as authentic)
                               2.2 A negative control or blank similar to the parent botanical (vouchered)
                               2.3 Concentrated powders and extracts
                               2.4 Tablets/pills and capsules (gel caps - hard or soft)
                               2.5 Combination products

                       3. Has the method been "optimized?" Have efforts been made to decrease run times, increase resolution, improve
                       peak shapes, minimize extraction time and improve extraction efficiency, separations, selectivity, and address stability.
                       Have tests for analyte stability during processing and under typical conditions of storage been addressed where
                       appropriate?

                       4 Has provision been made for confirmation of analyte identity? (The method may be sufficiently specific so that
Service List




                       confirmation of identity may not be necessary.)

                       5 Was ruggedness testing done during the method development phase identifying variables tested. Have these criteria
                       been written into the method? (Note: ruggedness delineates the limits of minor variables; optimization applies to major
                       variables.)

                       6 Are the following performance characteristics available?

                               6.1 The recommended analytical range is LOQ to 200% of expected analyte concentration.
                               6.2 Does calibration cover the analytical range? At least 5 concentrations should be used for calibration. Are
                               reference and internal standards available and is the source identified? Are reference standards stable as
                               prepared for use? (The stability of the analytical curve should also be established by duplicating it on another
                               day. Note: It has been repeatedly pointed out that a linear calibration curve is not a critical item, but merely a
                               convenience, and r values close to one may be deceptive [cf. Analyst 113, 1469 (1968)]. The calibration
Forms




                               curves for immunoassays are negative [0 concentration is a maximum] and exponential.)




                       Tel. (949) 419-0288           Fax. (949) 419-0294            email. sales@chromadex.com              www.chromadex.com
                                                                                                                                   13




                                                                                                                                        Introduction
                 Laboratory Validation Services
ChromaDex Single Labo




                                                                                                                                        Validation
          6.3 Accuracy/Recovery: Was recovery determined from spiked blanks or samples with at least 7 independent
          analyses per concentration level at a minimum of 3 concentration levels covering the analytical range.
          Independent means at least at different times. If no confirmed (natural) blank is available, the average inherent
          (naturally containing) level of the analyte should be determined on at least 7 independent replicates. Was
          accuracy determined using a Standard Reference Material from NIST if available or other certified reference
          material; or if possible, by reference to an internal standard. (It is critical during method development to establish
          a reference point to which all assays can be referred. When this material is ultimately assayed, all referred assays
          can be adjusted accordingly.
          6.4. Precision (repeatability, standard deviation): Were the number and types of analyses sufficient for obtaining a
          good estimate of accuracy? Typically for single lab validation one performs r replicate analyses of m test portions




                                                                                                                                        Example Reports
          over a period of d days for each sample type (matrix) n, where r is the number of replicates (2,3 …), m is the
          number of test portions in each group, d is the number of days, and n is the number of different sample types.
                   x r x m should never be less than 10
                   x n should be at least 2, preferably more
                   x d should be at least 2
          6.5 The calculated HORRAT value should lie between 0.5-2.0. The formula must be given to show that one is
          calculating the within-lab value.

  Recommended recovery and precision limits for single lab validation:
         Concentration              Repeatability (%)                 Recovery (%)
             100%                          1                             98-101
              10%                         1.5                            95-102
               1%                          2                             92-105




                                                                                                                                        Micro-Bio
              0.1%                         3                             90-108
             0.01%                         4                             85-110
        10Pg/g (10 ppm)                    6                             80-115
         1 Pg/g (1 ppm)                    8                             75-120
        10 ng/g(10 ppb)                  15 7                             0-125


  Recommended Format for SLV Study Report:
  1. Method identification: title, authors, contact information, published references



                                                                                                                                        Service List
  2. Applicability: scope, abstract clearly identifying the analyte(s), matrix(ices), analytical range, safety
  3. Principle: may be included in abstract
  4. Definitions (units if needed)
  5. Reagents/supplies: include reference standards, calibration standards, etc.
  6. Apparatus: include instruments and equipment used
  7. Sampling: types of samples, amounts, sample handling and storage, stability, preparation of test samples
  8. Method: include calibration and procedure and include or refer to #1
  9. Calculations summary: detection/quantification limits, recovery, precision, and additional information such as stability
  and measurement uncertainty (2RSDr)
  10. Other pertinent information; e.g. confirmation of analyte identity and ruggedness (may be placed in #8)
  11. Conclusions
                                                                                                                                        Forms




        Tel. (949) 419-0288        Fax. (949) 419-0294         email. sales@chromadex.com           www.chromadex.com
                  14
Introduction




                                                                Physico Chemical
                                DETERMINATION OF PHYSICO-CHEMICAL PROPERTIES Under GLP Conditions
Validation




                   Do you need to validate the physical chemical properties of your compound before doing a GLP study?
                   Our facilities operate under 25017025 standards and we have extensive experience in conducting GLP-studies. Currently, about 500
                   single GLP-studies including physico-chemical parameter studies and eco-toxicological studies are performed per year. We assign one
                   project manager to be responsible for the coordination of all single studies to be performed.
                   Guidelines to be followed for GLP physico-chemical characterization work proposed will follow the sponsor’s template.
                   Validation requirements for methods to be used under current Good Manufacturing Practices (cGMP) may include:
                            - United States Pharmacopoeia (USP) General Chapter 1225, Validation of Compendial Methods, USP29-NF24
Example Reports




                            - Validation of Analytical Procedures: Methodology, International Conference on Harmonization (ICH), June 1977
                            - U.S. Congressional Federal Register CFR 21_58
                            - Draft FDA Guidance for Industry on Analytical Procedures and Methods Validation: Chemistry, Manufacturing,
                              and Control Documentation, August 30, 2000.
                            - Organization for Economic Co-operation and Development (OECD) 30 member states including North America,
                              Europe, Japan, Australia, New Zealand … and others such as FIFRA and EPA registration guidelines.
                   Properties of aqueous solutions typically at 0.5%, 0.1%, 0.0015%
                            pH, refractive index, specific optical rotation, viscosity, surface tension, solution density, specific gravity
                   Solubility properties typically at 15, 25, 40, 50, 60 degrees centigrade
                            In water, in ethanol, and finished product dissolution rate
                            Equilibrium conditions
                            Partition coefficient between octanol and water (UV/VIS or HPLC measurement)
Micro-Bio




                            Dissociation constants (pKa)
                   Bulk Density
                           Aerated, Packed, Compressibility
                   Thermal characteristics
                           Melting point range
                           Thermogravimetric analysis (TGA)
                           Differential scanning calorimetry (DSC)
                   Elemental analysis
                           Classical (C, H, N, O)
Service List




                           ICP/OES, ICP/MS
                   Spectroscopic characteristics
                           Infrared
                           UV/VIS absorption
                           1H NMR
                           13C NMR
                           Mass - Chemical Ionization, Electron Impact Ionization, MALDI
                   Chromatographic characteristics
                          HPLC / GC purity
                          Chirality
                   Structural characterization
Forms




                            2D-NMR (NOESY, COSY, HSQC, HMBC)
                            X-ray diffraction crystallography, including full graphic presentation

                                Tel. (949) 419-0288          Fax. (949) 419-0294           email. sales@chromadex.com             www.chromadex.com
                                                                                                                                         15




                                                                                                                                               Introduction
                                                                                                                                               Validation
                 ChromaDex Report Examples
                                     ChromaDex Contract Services Report Types
ChromaDex offers a rapidly expanding list of contract services. Choosing the correct report is often as important as choosing the correct
assay for your testing needs. Your testing results may be reported in two different formats and vary in the level of information reported as
related to the testing procedure. All ChromaDex reports will include a unique report number, notebook reference, and issue date. Please




                                                                                                                                               Example Reports
see the descriptions of our two reporting types below. Should there be any questions about which of the two report formats best suits your
company’s needs, do not hesitate in contacting a ChromaDex sales representative who will explain the two report formats in detail.

Detailed Report – Analytical Test Report (ATR) – HPTLC, TLC
As the most detailed of our report types, Analytical Test Reports not only report results but also contain detailed information on the test
method and protocol. ATR’s are always recommended for any first time analysis as well as all research work. ATR’s will include, but are
not limited to the following information:
         1.       Materials and equipment involved in the test
         2.       Calibration series data when determined in a test
         3.       Detailed sample preparation instructions
         4.       Detailed analytical conditions for the test
         5.       Comments and conclusions regarding the test results




                                                                                                                                               Micro-Bio
         6.       Supporting data for the results such as chromatograms, spectra, images, etc. for the sample and standards in the test
         7.       Any references related to the test protocol

Detailed Report – Analytical Test Report (ATR) – HPLC, GC or UV
As the most detailed of our report types, Analytical Test Reports not only report results but also contain detailed information on the test
method and protocol. ATR’s are always recommended for any first time analysis as well as all research work. This report type is available
for HPLC, GC and UV analysis. ATR’s will include, but are not limited to the following information:
         1.       The objective of the test
         2.       Any chemical structures related to the test
         3.       Materials and equipment involved in the test


                                                                                                                                               Service List
         4.       Calibration series data when determined in a test
         5.       Detailed sample preparation instructions
         6.       Detailed analytical conditions for the test
         7.       Results summary in table or paragraph format
         8.       Supporting data for the results such as chromatograms, spectra, images, etc. for the sample and standards in the test
         9.       Any references related to the test protocol


Basic Report – Assay Results Sheet (ARS)
As our basic report, Assay Results Sheets provide an economical alternative perfect for repeated testing after the generation of the initial
ATR. ARS’s are useful for repeat raw material and quality control tests run on a consistent basis. ARS’s will include the following informa-
tion:
                                                                                                                                               Forms




         1.       Reported result for marker detection (for HPLC)
         2.       Identity results (for TLC)

         Tel. (949) 419-0288         Fax. (949) 419-0294           email. sales@chromadex.com            www.chromadex.com
                  16
Introduction




                                                                             ChromaDex Report Examples
Validation




                  HPTLC ATR Report Example
                      • Designed for qualitative work.
                      • Provides a fingerprint for botanicals.
Example Reports




                                         ChromaDex Analytics                                                            Research & Development
                                                            (303) 442-4281                                                      2830 Wilderness Place, Boulder, CO 80301

                                                                                        HPTLC Test Report
                                                HPTLC Analysis of 50:1 Extract of Sambucus nigra (Elderberry)
                                  Report Number: CDXA-HPTLC-ATR-XXX          Project Number: XXXXX
                                  Issue Date: XX-XXX-XXXX                    Page: 1 of 2


                                 Company Name:                          XXXXXX
                                 Plant Name:                            Elderberry
                                 Latin Name:                            Sambucus nigra
                                 Plant Part:                            Fruit
                                 Date received:                         XX XXX XXXX
                                 Sample Description:                    Dark red powder
                                 Lot #:                                 XXX
Micro-Bio




                                 Control #:                             XXXXX
                                 Sample #:                              CDXA-XX-XXXX (XXX)
                                 Reference Sample #:                    CDXA-XX-XXXX (XXX) Sambucus nigra, L. [Caprifoliaceae]
                                 Reference Standard:                    Kuromanin chloride (1 mg/mL in methanol, CDXA-XX-XXXX)
                                 Literature Source(s):                  Derived from Standards of Analysis, Quality Control, and Therapeutics:
                                                                        Bilberry Fruit, Vaccinium myrtillus L, American Herbal Pharmacopoeia and
                                                                        Therapeutic Compendium, Upton, R., Ed. American Herbal
                                                                        Pharmacopoeia: Santa Cruz, 2001; Herbal Drugs and
                                                                        Phytopharmaceuticals: A Handbook for Practice on a Scientific Basis, 4th
                                                                        ed., pg 549; CDXA-TLCM-047-00; CDXA0XX pg. xx-xx.

                                 Comments and Conclusions:
Service List




                                 The HPTLC analysis of the sample, Elderberry Extract PE 50:1, shows a chromatographic
                                 fingerprint which is characteristic of an extract of Sambucus nigra and conforms to the profile as
                                 described in the literature sources listed above. Under white light, both the reference material and
                                 sample show strong purple bands, which correspond to the anthocyanins, at Rf #, 0.56, and 0.68
                                 (Kuromanin) with lesser bands at Rf # 0.39 and 0.47. Under 365 nm, the same colored bands now
                                 fluoresce dark red for the stronger bands and bright red for the lesser bands. The sample does not
                                 show the light blue bands that partially obscure the anthocyanin bands as seen in the reference
                                 material. After anisaldehyde staining and white light, both the reference material and sample show
                                 broad distinctive bands at Rf # 0.27 and 0.36 (dark green), though at a lower concentration in the
                                 sample, and two bands centered at Rf # 0.63 (yellow and green). The reference also shows
                                 additional green bands Rf # 0.51, 0.66, and 0.76, and a dark blue band near the solvent front.
                                 These bands are not evident in the sample material at its current concentration.
Forms




                                      This document has a digital signature on the last page. The digital signature must be verified for this document to be authentic.
                                      This product analysis is subject to our General Terms and Conditions of Business, including our services and reports, and is for the benefit of our
                                      client only and may not be relied upon by any other party and relates solely to the sample(s) in our possession and cannot be applied to any other
                                      material.




                          Tel. (949) 419-0288                    Fax. (949) 419-0294                              email. sales@chromadex.com                                      www.chromadex.com
                                                                                                                                                                                                 17




                                                                                                                                                                                                      Introduction
ChromaDex Report Examples




                                                                                                                                                                                                      Validation
                           HPTLC Analysis of 50:1 Extract of Sambucus nigra (Elderberry)
                   CDXA-HPTLC-ATR-0XX-00                                          Page 2 of 2

            HPTLC:

            Sample Preparation:                                          0.2 g (sample) or 0.5 g (reference) + 10 mL methanol
                                                                         sonicated in water bath @ RT for 10 minutes, extracted @
                                                                         65° C for 60 minutes, filtered using 0.45 μ PTFE syringe
                                                                         filter, adjusted to 10 mL volume.




                                                                                                                                                                                                      Example Reports
            Stationary Phase:                                            Silica gel 60, F254, 10 x 10 cm HPTLC plates
            Mobile Phase:                                                n-Butanol/ formic acid/ water (40:10:15)
            Development Conditions:                                      Conditioned 30 min. with saturation pad
            Detection:                                                   (1) White light
                                                                         (2) UV 365 nm
                                                                         (3) Anisaldehyde/sulfuric acid spray reagent White light
            Images:



                              HP-TLC (1)                                              HP-TLC (2)                                                              HP-TLC (3)




                                                                                                                                                                                                      Micro-Bio
              1 2 3       4    5    6     7 8      9 10             1 2 3         4     5   6      7 8        9 10                    1 2 3                4       5      6   7 8     9 10


                                                                   Yellow line = sample origin
                                                                   Red line = solvent front @ 60mm




                                                                                                                                                                                                      Service List
            TLC Plate Lane Assignments:
            Lane         Amt. app.                         ID                                   Lane                 Amt. app.                                    ID
              1            2 μL                        Kuromanin                                 6                     1 μL                                Sample Extract #2
              2            4 μL                   Reference Extract #1                           7                     2 μL                                Sample Extract #2
              3            8 μL                   Reference Extract #1                           8                     4 μL                               Reference Extract #2
              4            1 μL                    Sample Extract #1                             9                     8 μL                               Reference Extract #2
              5            2 μL                    Sample Extract #1                             10                    4 μL                                   Kuromanin



           AUTHOR: XXXX XXXX                                                                         Digitally signed by Sheryl Verbitski, Ph.D.                          D A T E : XX X X X X
           APPROVED BY: XXXX XXXX
                                                      Sheryl Verbitski, Ph.D.                        DN: CN = Sheryl Verbitski, Ph.D., C = US, O = Chromadex Analytics,
                                                                                                     OU = Bioluminex Manager
                                                                                                     Date: 2006.01.12 09:59:28 -07'00'
                                                                                                                                                                          D A T E : XX X X X X

                 This document has a digital signature on the last page. The digital signature must be verified for this document to be authentic.
                 This product analysis is subject to our General Terms and Conditions of Business, including our services and reports, and is for the benefit of our
                                                                                                                                                                                                      Forms




                 client only and may not be relied upon by any other party and relates solely to the sample(s) in our possession and cannot be applied to any other
                 material.




Tel. (949) 419-0288                Fax. (949) 419-0294                          email. sales@chromadex.com                                                      www.chromadex.com
                  18
Introduction
Validation




                                                                                  ChromaDex Report Examples
                   Analytical Test Report (ATR)
                       • Highest level of detail provided on reports.
                       • Provides step-by-step instructions to perform the assay.
Example Reports




                       • Listing of lot numbers of standards, reagents, chromatograms of
                         standards and samples.
                                                                                                                                                                  (OODJLF $FLG LQ 3RPHJUDQDWH ([WUDFW
                                                                                                                                         &';$$75;;;;;                                                        3DJH  RI 

                                                                                                                                          2%-(&7,9(
                           &KURPD'H[ $QDO\WLFV                                    5HVHDUFK                  'HYHORSPHQW
                                                                             :LOGHUQHVV 3ODFH %RXOGHU &2                 7R GHWHFW DQG TXDQWLI\ (OODJLF $FLG LQ GULHG SRPHJUDQDWH H[WUDFW
                                  &KURPD'H[ $QDO\WLFV $QDO\WLFDO 7HVW 5HSRUW
                                                                                                                                          6$03/(6
                                            (OODJLF $FLG LQ 3RPHJUDQDWH ([WUDFW
                                                                                                                                                   3RPHJUDQDWH ([WUDFW &';$;;;;;;
                       5HSRUW 1XPEHU &';$$75;;;                          5HYLVLRQ 
Micro-Bio




                       3URMHFW 1XPEHU 25';;;;;                                ,VVXH 'DWH                                                67$1'$5'6
                                                                               3DJH  RI 
                                                                                                                                                   (OODJLF $FLG &';$6

                         3UHSDUHG %\
                                                  6HQLRU $QDO\WLFDO &KHPLVW                      'DWH                                         6758&785(6
                                                                                                                                                                                          2

                                                                                                                                                                   +2            2
                         5HYLHZHG %\
                                                  'LUHFWRU $QDO\WLFDO 6HUYLFHV                  'DWH

                                                                                                                                                             +2                                         2+

                         $SSURYHG %\
                                                  'LUHFWRU $QDO\WLFDO 6HUYLFHV                  'DWH
                                                                                                                                                                                      2            2+
Service List




                                                                                                                                                                             2
                         6LJQHG RULJLQDO RQ ILOH DW &';$
                                                                                                                                                                                (OODJLF $FLG
                                                                                                                                                                                  &+2
                                                                                                                                                                              0RO :W 
                                                                                                                                                                         &  +  2 


                                                                                                                                          62/9(176 $1' 5($*(176

                                                                                                                                                   0LOOL4 :DWHU
                                                                                                                                                   $FHWRQLWULOH $&1 +3/& *UDGH
                                                                                                                                                   $PPRQLXP )RUPDWH 1+22&+
                         7KLV SURGXFW DQDO\VLV LV VXEMHFW WR RXU *HQHUDO 7HUPV DQG &RQGLWLRQV RI %XVLQHVV LQFOXGLQJ RXU VHUYLFHV                  )RUPLF $FLG   +&22+
                         DQG UHSRUWV DQG LV IRU WKH EHQHILW RI RXU FOLHQW RQO\ DQG PD\ QRW EH UHOLHG XSRQ E\ DQ\ RWKHU SDUW\ DQG
                         UHODWHV VROHO\ WR WKH VDPSOHV LQ RXU SRVVHVVLRQ DQG FDQQRW EH DSSOLHG WR DQ\ RWKHU PDWHULDO
Forms




                                       Tel. (949) 419-0288                                  Fax. (949) 419-0294                     email. sales@chromadex.com                       www.chromadex.com
                                                                                                                                                                                                                                                                                     19




                                                                                                                                                                                                                                                                                          Introduction
                                                                                                                                                                                                                                                                                          Validation
                                      (OODJLF $FLG LQ 3RPHJUDQDWH ([WUDFW
 &';$$75;;;;;                                                                                                     3DJH  RI 

 (48,30(17                                                                                                                                              • Structure(s)
                  $JLOHQW  +3/& 6\VWHP ZLWK 9:' ,QJROG
                  3KHQRPHQH[ /XQD —P 3KHQ\O+H[\O  [  PP —P




                                                                                                                                                                                                                                                                                          Example Reports
                  $QDO\WLFDO %DODQFH 0HWWOHU 7ROHGR $;
                  $TXDVRQLF 0RGHO 7 8OWUDVRQLF %DWK
                  $VVRUWHG YROXPHWULF JODVVZDUH
                                                                                                                                                                                    • Reagent List
 62/87,216

                  0RELOH 3KDVH $

                      0RELOH 3KDVH $ LV XQGLOXWHG +3/& *UDGH $FHWRQLWULOH
                                                                                                                                                                                                                       • Equipment List
                  0RELOH 3KDVH %

                      0RELOH 3KDVH % LV  P0 $PPRQLXP )RUPDWH LQ 0LOOL4 :DWHU S+
                      DGMXVWHG WR  XVLQJ )RUPLF $FLG 3UHSDUHG E\ DGGLQJ  PJ
                      $PPRQLXP )RUPDWH WR  / RI 0LOOL4 :DWHU DQG XVLQJ GURSZLVH
                      DGGLWLRQ RI IRUPLF DFLG WR DGMXVW WKH S+

                  6WRFN 6WDQGDUG 6ROXWLRQV

                      7KH VWRFN VWDQGDUG VROXWLRQV ZHUH HDFK SUHSDUHG DV IROORZV 7KH
                      VWDQGDUG FRPSRXQG ZDV ZHLJKHG LQWR D WDUHG  P/ YLDO 7KH
                      VWDQGDUG ZDV GLVVROYHG E\ DGGLQJ  P/ RI 0HWKDQRO WR WKH YLDO                                                                                                 (OODJLF $FLG LQ 3RPHJUDQDWH ([WUDFW
                      ZKLFK ZDV WKHQ FDSSHG DQG VKDNHQ WR GLVVROYH WKH PDWHULDO 7KH                                                              &';$$75;;;;;                                                                                                     3DJH  RI 
                      DFWXDO ZHLJKWV DQG FRQFHQWUDWLRQV DUH VKRZQ LQ WKH WDEOH EHORZ




                                                                                                                                                                                                                                                                                          Micro-Bio
                                                                                                                                                                           67$1'$5'
                                                                                                       &21&(175$7,21                                                         /(9(/
                                                                                                                                                                                                 —/ 0L[HG 6WDQGDUG                                (OODJLF $FLG &RQFHQWUDWLRQ SSP
               &203281'                     &';$ 180%(5                      0$66 PJ
                                                                                                           SSP                                                                                                                                            
                (OODJLF $FLG               &';$6                                                                                                                                                                                         
                                                                                                                                                                                                                                                           
                                                                                                                                                                                                                                                          
                  &DOLEUDWLRQ 6HULHV                                                                                                                                                                                                                  
                      7KH FDOLEUDWLRQ VHULHV ZDV SUHSDUHG E\ GLOXWLQJ VSHFLILHG YROXPHV RI
                      WKH PL[HG VWDQGDUG VROXWLRQ WR  P/ ZLWK 0HWKDQRO 7KLV LV
                                                                                                                                                                       7KH ILYH SRLQW FDOLEUDWLRQ FXUYH LV VKRZQ EHORZ
                      VXPPDUL]HG LQ WKH WDEOH EHORZ
                                                                                                                                                                       (OODJLF $FLG
                                                                                                                                                                                                           (OODJLF $FLG 9:' $
                                                                                                                                                                                                           $UHD 
$PW 
                                                                                                                                                                                                    $UHD 5HO 5HV  


                                                                                                                                                                                                                                              

                                                                                                                                                                                                   

                                                                                                                                                                                                   
                                                                                                                                                                                                                             
                                                                                                                                                                                                    

                                                                                                                                                                                                    
                                                                                                                                                                                                                   
7KLV GRFXPHQW KDV D GLJLWDO VLJQDWXUH RQ WKH ODVW SDJH 7KH GLJLWDO VLJQDWXUH PXVW EH YHULILHG IRU WKLV GRFXPHQW WR EH DXWKHQWLF                                                                   
                                                                                                                                                                                                               
                                                                                                                                                                                                                   

                                                                                                                                                                                                                                 &RUUHODWLRQ 




                                                                                                                                                                                                                                                                                          Service List
                                                                                                                                                                                                                                      $PRXQW>QJXO@




                                                                                                                                                  6$03/( 35(3$5$7,21

                                                                                                                                                                   6DPSOH 3UHSDUDWLRQ

                                                                                                                                                                       $SSUR[LPDWHO\  PLOOLJUDPV ZHUH ZHLJKHG LQWR D  P/
• Calibration Data                                                                                                                                                     YROXPHWULF IODVN 0HWKDQRO ZDV DGGHG DQG WKH PL[WXUH ZDV
                                                                                                                                                                       VRQLFDWHG LQ WKH XOWUDVRQLF EDWK IRU  PLQXWHV FRROHG DQG PDGH
                                                                                                                                                                       XS WR H[DFWO\  P/ ZLWK 0HWKDQRO 7KH\ ZHUH WKHQ VKDNHQ
                                                                                                                                                                       YLJRURXVO\ WR HQVXUH WKRURXJK PL[LQJ $Q DOLTXRW ZDV ILOWHUHG
                                                                                                                                                                       WKURXJK D  —P V\ULQJH ILOWHU SULRU WR DQDO\VLV 7KH DFWXDO
                                                                                                                                                                       DPRXQWV DUH WDEXODWHG LQ WKH WDEOH EHORZ
                     • Sample Preparation                                                                                                                                                6$03/(                                           0$66 PJ
                                                                                                                                                                                       &';$;;;;;;                                         ;;;;


                                                                                                                                                  $1$/<7,&$/ 0(7+2'

                                            • Method                                                                                                               0HWKRG

                                                                                                                                                            +3/&                                               $JLOHQW  +3/& ZLWK D 9:' ,QJROG 
                                                                                                                                                            &ROXPQ                                             3KHQRPHQH[ /XQD —P 3KHQ\O+H[\O
                                                                                                                                                                                                                                                                                          Forms




                                                                                                                                                                                                                [  PP



                                                                                                                                                 7KLV GRFXPHQW KDV D GLJLWDO VLJQDWXUH RQ WKH ODVW SDJH 7KH GLJLWDO VLJQDWXUH PXVW EH YHULILHG IRU WKLV GRFXPHQW WR EH DXWKHQWLF




      Tel. (949) 419-0288                                                     Fax. (949) 419-0294                                   email. sales@chromadex.com                                                             www.chromadex.com
                  20
Introduction
Validation




                                ChromaDex Report Examples
                                                              (OODJLF $FLG LQ 3RPHJUDQDWH ([WUDFW
                         &';$$75;;;;;

                                      0RELOH 3KDVHV                              $ ± +3/& *UDGH $FHWRQLWULOH
                                                                                                                                             3DJH  RI 
                                                                                                                                                                 • Results
                                                                                 % ±  P0 $PPRQLXP )RUPDWH S+                                    
                                                                                 DGMXVWHG ZLWK IRUPLF DFLG
                                      *UDGLHQW
                                                                                    7,0( PLQXWHV                              $               %

                                                                                                                                                                            • Data
Example Reports




                                                                                                                                         
                                                                                                                                         

                                      7HPSHUDWXUH                                 ƒ&
                                      )ORZ 5DWH                                   P/PLQ
                                      ,QMHFWLRQ 9ROXPH                            —/


                         5(68/76
                                      89 'HWHFWLRQ                                QP
                                                                                                                                                                                          • Reference Chromatogram
                                                            6$03/(                                                (OODJLF $FLG
                                                          &';$;;;;;;                                                ;;;;



                         &+520$72*5$06

                             )LJXUH  89 &+520$72*5$0 RI 67$1'$5'  QP
                                   9:' $ :DYHOHQJWK  QP *?*B'
                                                                                       (OODJLF $FLG




                           1RUP

                            


                                                                                                                                                                                            (OODJLF $FLG LQ 3RPHJUDQDWH ([WUDFW
                                                                                                                                                                    &';$$75;;;;;                                                                                   3DJH  RI 
                            
Micro-Bio




                                                                                                                                                                  )LJXUH  89 &+520$72*5$0 RI &';$;;;;;;  QP
                                                                                                                                                                            9:' $ :DYHOHQJWK  QP *?*B'
                                                                                                                                                                  1RUP

                                                                                                                                                                  
                                                                                                                                                                                                                          (OODJLF $FLG




                                                                                                                                                                  
                                                                                   




                              
                                                                                                                                                                     
                                                                                                                                                     PL

                                                                                                                                                                     


                                                                                                                                                                      


                                                                                                                                                                      

                        7KLV GRFXPHQW KDV D GLJLWDO VLJQDWXUH RQ WKH ODVW SDJH 7KH GLJLWDO VLJQDWXUH PXVW EH YHULILHG IRU WKLV GRFXPHQW WR EH DXWKHQWLF
                                                                                                                                                                      
                                                                                                                                                                                                     




                                                                                                                                                                                                                     
                                                                                                                                                                                                             
                                                                                                                                                                                                                     
                                                                                                                                                                                                                     
Service List




                                                                                                                                                                       
                                                                                                                                                                                                                                                                           PL




                       • Sample Chromatogram                                                                                                                         5()(5(1&(6

                                                                                                                                                                               &KURPD'H[ $QDO\WLFV /DE 1RWHERRN  SDJH 


                                         • References                                                                                                                +,6725< 2) 5(9,6,216

                                                                                                                                                                                  'DWH         5HYLVLRQ                                              7LWOH&KDQJHV
                                                                                                                                                                                                                                        1HZ $75 ³(OODJLF $FLG LQ 3RPHJUDQDWH

                                                                 • History of Revisions                                                                                                                                                                  ([WUDFW´
Forms




                                                Tel. (949) 419-0288                                                             Fax. (949) 419-0294               email. sales@chromadex.com                                                       www.chromadex.com
                                                                                                                                                                    21




                                                                                                                                                                         Introduction
 ChromaDex Report Examples




                                                                                                                                                                         Validation
Analytical Results Sheet (ARS) Report
    • Basic report details.

                                               ChromaDex                                            Research & Development
                                                  ph 727 573-9229                                                      13161 56th Court, Ste 201
                                                   fx 727 573-9220                                                       Clearwater, FL 33760




                                                                                                                                                                         Example Reports
                                                                            Assay Result Sheet
                     Number:                   ARS-XXXXX-0             Sample Name:                 Multi-Vitamin Capsules
                     Date:                     7/7/2005                Sample Lot #:                S1234                Control #:              UXXXX


                                                                                                                                     Date          Notebook
                               Test                   Method                     Specs                       Results                Tested         Reference

                             Folic Acid                USP 26                   NLT 95%                      96.1%                6/27/2005        RD000-000
                                                       (HPLC)                                                  as is


                           Thiamine HCl          CD-ATM-018-03-00              25 mg/cap                 26.2 mg/cap               7/5/2005        RD000-000
                                                       (HPLC)                                                105% LC


                            Niacinamide          CD-ATM-018-03-00              100 mg/cap                98.7 mg/cap               7/5/2005        RD000-000
                                                       (HPLC)                                               98.7% LC
                     Assay Result Sheet




                                                                                                                                                                         Micro-Bio
                         For Demonstration
                          Purposes Only




                                                                                                                                                                         Service List
                                                                     Results are average of 3 replicate injections.
                                           Documentation to support these results are on file at ChromaDex and are available upon request.


                                                                       Results are rounded to three significant figures


                                                     Approved By:
                                                                                    Mark Roman, Ph.D.
                                                                             Director, Research & Development
                                                                                                                                                                         Forms




                    This product analysis is subject to our General Terms and Conditions of Business, including our services and reports, and is
                    for the benefit of our client only and may not be relied upon by any other party and relates solely to the sample(s) in our
                    possession and cannot be applied to any other material.




   Tel. (949) 419-0288                    Fax. (949) 419-0294                      email. sales@chromadex.com                                   www.chromadex.com
                  22
Introduction




                       Microbiological Testing Services
Validation




                       FULL MICROBIOLOGICAL PANEL                          Service Code#      CDA-00100254-ARS
                       Panel Includes:
                       1. Total Plate Count
                       2. Total Yeast and Mold Count
                       3. Coliform - E. Coli Count
                       4. Staph aureus Count
                       5. Salmonella
                                                                               Price per Sample
Example Reports




                       Testing                              1 Sample       2-4 Samples     5-9 Samples   10+ Samples
                       Full Micro Panel                      $      155.00 $        124.00 $      108.50 $      93.00


                       TOTAL AEROBIC PLATE COUNT                           Service Code# CDA-00100087-ARS
                                                                               Price per Sample
                       Testing                              1 Sample       2-4 Samples     5-9 Samples   10+ Samples
                       Total Aerobic plate count             $       45.00 $         36.00 $       31.50 $      27.00

                       TOTAL YEAST AND MOLD PANEL                          Service Code# CDA-00100251-ARS
                                                                               Price per Sample
                       Testing                              1 Sample       2-4 Samples     5-9 Samples   10+ Samples
Micro-Bio




                       Total Yeast and Mold Panel            $       45.00 $         36.00 $       31.50 $      27.00

                       COLIFORM - E. COLI COUNT                            Service Code# CDA-00100252-ARS
                                                                               Price per Sample
                       Testing                              1 Sample       2-4 Samples     5-9 Samples   10+ Samples
                       Coliform -E. Coli Panel               $       45.00 $         36.00 $       31.50 $      27.00

                       ENTEROBACTERIACEAE COUNT                            Service Code# CDA-00100347-ARS
                                                                               Price per Sample
                       Testing                              1 Sample       2-4 Samples     5-9 Samples   10+ Samples
Service List




                       Enterobacteriaceae Panel              $       65.00 $         52.00 $       45.50 $      39.00

                       PSEUDOMONAS COUNT                                   Service Code# CDA-00100257-ARS
                                                                               Price per Sample
                       Testing                              1 Sample       2-4 Samples     5-9 Samples   10+ Samples
                       Pseudomonas Panel                     $       55.00 $         44.00 $       38.50 $      33.00

                       LISTERIA PANEL                                      Service Code# CDA-00100256-ARS
                                                                               Price per Sample
                       Testing                              1 Sample       2-4 Samples     5-9 Samples   10+ Samples
                       Listeria Panel                        $       65.00 $         52.00 $       45.50 $      39.00
Forms




                              Tel. (949) 419-0288   Fax. (949) 419-0294    email. sales@chromadex.com    www.chromadex.com
                                                                                                  23




                                                                                                       Introduction
Microbiological Testing Services




                                                                                                       Validation
SALMONELLA COUNT                                     Service Code# CDA-00100255-ARS
                                                         Price per Sample
Testing                               1 Sample       2-4 Samples     5-9 Samples   10+ Samples
Salmonella Panel                       $       65.00 $         52.00 $       45.50 $      39.00

STAPH AUREUS PANEL                                   Service Code# CDA-00100253-ARS
                                                         Price per Sample
Testing                               1 Sample       2-4 Samples     5-9 Samples   10+ Samples




                                                                                                       Example Reports
Staph Aureus Panel                     $       65.00 $         52.00 $       45.50 $      39.00

E. COLI 0157:H7 COUNT                                Service Code# CDA-00100348-ARS
                                                         Price per Sample
Testing                               1 Sample       2-4 Samples     5-9 Samples   10+ Samples
E. Coli 0157:H7 Panel                  $      100.00 $         80.00 $       70.00 $      60.00




                                                                                                       Micro-Bio
                                                                                                       Service List
                                                                                                       Forms




 Tel. (949) 419-0288    Fax. (949) 419-0294     email. sales@chromadex.com   www.chromadex.com
                  24
Introduction
Validation
Example Reports
Micro-Bio
Service List
Forms




                       Tel. (949) 419-0288   Fax. (949) 419-0294   email. sales@chromadex.com   www.chromadex.com
                                                                                                                                      25




                                                                                                                                            Introduction
                                                                                                                                            Validation
                                                                                      Cost per Sample($)
SERVICE DESCRIPTION                                           Report 1 Sample 2-4     5-9     10+                        Service Code
                                                              Type            Samples Samples
Accelerated Stability Study                                   ATR    $850.00      $680.00        $595.00       $510.00   CDA-00100232-ATR
Acetyl-L-Carnitine by HPLC                                    ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100297-ARS
Acetyl-L-Tyrosine by HPLC                                     ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100318-ARS
Alanine by HPLC                                               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100364-ARS




                                                                                                                                             Example Reports
Alanine by HPLC                                               ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100364-ATR
Alfalfa Identity Testing by TLC                               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100039-ARS
Alfalfa Identity Testing by TLC                               ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100039-ATR
Algae powder for Chlorophyll by HPLC                          ARS    $250.00      $200.00        $175.00       $150.00   CDA-00003010-ARS
Algae powder for Chlorophyll by HPLC                          ATR    $350.00      $280.00        $245.00       $210.00   CDA-00003010-ATR
Algae powder for Chlorophyll by UV-Spec                       ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100317-ARS
Allergen Testing: Soybean by ELISA                            ARS    $325.00      $260.00        $227.50       $195.00   CDA-00100200-ARS
Allergen Testing: Wheat Gluten by ELISA                       ARS    $325.00      $260.00        $227.50       $195.00   CDA-00100198-ARS
Allergen Testing: Peanut by ELISA                             ARS    $325.00      $260.00        $227.50       $195.00   CDA-00100199-ARS
Aloe Vera by HPLC                                             ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100149-ARS
Aloe Vera by HPLC                                             ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100149-ATR




                                                                                                                                             Micro-Bio
Amino Acid Analysis                                           ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100140-ARS
Amino Acid Analysis                                           ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100140-ATR
Amino Butyric Acid by HPLC                                    ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100365-ARS
Amino Butyric Acid by HPLC                                    ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100365-ATR
Andrographis for Andrographolides by HPLC                     ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100133-ARS
Andrographis for Andrographolides by HPLC                     ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100133-ATR
Apple Extract Identity Testing by TLC                         ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100012-ARS
Apple Extract Identity Testing by TLC                         ATR    $300.00      $240.00        $210.00       $180.00   CDA-00100012-ATR
Arginine Ethyl Ester by HPLC                                  ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100143-ARS




                                                                                                                                            Service List
Arginine (L-) by HPLC                                         ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100152-ARS
Arginine (L-) by HPLC                                         ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100152-ATR
Aristolochia Testing by HPLC/MS                               ARS    $395.00      $316.00        $276.50       $237.00   CDA-00100072-ARS
Aristolochia Testing by HPLC/MS                               ATR    $495.00      $396.00        $346.50       $297.00   CDA-00100072-ATR
Aristolochia Testing by HPLC/UV                               ARS    $300.00      $240.00        $210.00       $180.00   CDA-00100071-ARS
Artichoke for Cynarin by HPLC                                 ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100311-ARS
Artichoke for Cynarin by HPLC                                 ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100311-ATR
Artichoke Identity by HPTLC                                   ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100214-ARS
Artichoke Identity by HPTLC                                   ATR    $300.00      $240.00        $210.00       $180.00   CDA-00100214-ATR
Ascorbic Acid (L-) by HPLC                                    ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100194-ARS
Ascorbic Acid (L-) by HPLC                                    ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100194-ATR
                                                                                                                                             Forms




Ashwagandha for Withanolides by HPLC                          ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100093-ARS
Ashwagandha for Withanolides by HPLC                          ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100093-ATR
Ashwaghanda for Identity by TLC                               ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100359-ARS


      Tel. (949) 419-0288               Fax. (949) 419-0294         email. sales@chromadex.com             www.chromadex.com
                  26
Introduction
                                                                                                            Cost per Sample($)
                  SERVICE DESCRIPTION                                        Report 1 Sample 2-4     5-9     10+                              Service Code
                                                                             Type            Samples Samples
                  Ashwaghanda for Identity by TLC                            ATR         $300.00         $240.00      $210.00     $180.00     CDA-00100359-ATR
                  Asparagine by HPLC                                         ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100367-ARS
                  Asparagine by HPLC                                         ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100367-ATR
                  Aspartame (Nutrasweet) by HPLC                             ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100324-ARS
                  Aspartic Acid by HPLC                                      ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100350-ARS
                  Aspartic Acid by HPLC                                      ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100350-ATR
Validation




                  Aspirin By USP method                                      ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100190-ARS
                  Bacopa for Bacosides by HPLC/ELSD                          ARS         $300.00         $240.00      $210.00     $180.00     CDA-00100097-ARS
                  Bacopa for Bacosides by HPLC/ELSD                          ATR         $400.00         $320.00      $280.00     $240.00     CDA-00100097-ATR
                  Bacopa Identity Testing by TLC                             ARS         $200.00         $160.00      $140.00     $120.00     CDA-00100061-ARS
                  Banaba Analysis for Corosolic Acid by HPLC                 ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100329-ARS
                  Banaba Analysis for Corosolic Acid by HPLC                 ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100329-ATR
                  Barberry for Berberine by HPLC                             ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100206-ARS
                  Barberry for Berberine by HPLC                             ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100206-ATR
Example Reports




                  Barley Grass Identity Testing by Microscopy                ARS         $200.00         $160.00      $140.00     $120.00     CDA-00100051-ARS
                  Barley Grass Identity Testing by TLC                       ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100050-ARS
                  Barley Grass Identity Testing by TLC                       ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100050-ATR
                  Benzoic Acid by HPLC                                       ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100301-ARS
                  Benzopyrene by GCMS                                        ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100165-ATR
                  Berry (Bilberry) for Anthocyanidins by HPLC(CDX)           ARS         $250.00         $200.00      $175.00     $150.00     CDA-00002002-ARS
                  Berry (Bilberry) for Anthocyanidins by HPLC(CDX)           ATR         $350.00         $280.00      $245.00     $210.00     CDA-00002002-ATR
                  Berry (Bilberry) for Anthocyanidins by HPLC(Indena)        ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100242-ARS
                  Berry (Bilberry) for Anthocyanidins by HPLC(Indena)        ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100242-ATR
                  Berry (Bilberry) for Anthocyanidins by UV Spec             ARS         $200.00         $160.00      $140.00     $120.00     CDA-00002010-ARS
                  Berry (Bilberry) for Anthocyanidins by UV Spec             ATR         $300.00         $240.00      $210.00     $180.00     CDA-00002010-ATR
Micro-Bio




                  Beta-Carotene by HPLC                                      ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100371-ARS
                  Beta-Carotene by HPLC                                      ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100371-ATR
                  Betaine Analysis by HPLC                                   ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100235-ARS
                  Bilberry for Identity by TLC                               ARS         $200.00         $160.00      $140.00     $120.00     CDA-00100387-ARS
                  Bilberry for Identity by TLC                               ATR         $300.00         $240.00      $210.00     $180.00     CDA-00100387-ATR
                  BIOASSAY: P70S6 Kinase Inhibition                          ATR         $1,495.00       $1,196.00    $1,046.50   $897.00     CDA-BCA38-ATR
                  BIOASSAY: 15 - Lipoxygenase Inhibition Assay               ATR         $995.00         $796.00      $696.50     $597.00     CDA-BCA17-ATR
                  BIOASSAY: ABTS Radical Scavenging Assay                    ATR         $495.00         $396.00      $346.50     $297.00     CDA-BCA04-ATR
                  BIOASSAY: Acetylcholinesterase Inhibition Assay*           ATR         $395.00         $316.00      $276.50     $237.00     CDA-BCA05-ATR
Service List




                  BIOASSAY: Aldolase Inhibition Assay                        ATR         $395.00         $316.00      $276.50     $237.00     CDA-BCA22-ATR
                  BIOASSAY: Alpha-Amylase Inhibition Assay                   ATR         $395.00         $316.00      $276.50     $237.00     CDA-BCA01-ATR
                  BIOASSAY: Alpha-Glucosidase Inhibition Assay               ATR         $395.00         $316.00      $276.50     $237.00     CDA-BCA02-ATR
                  BIOASSAY: Angiotensin converting enzyme inhibition         ATR         $1,875.00       $1,500.00    $1,312.50   $1,125.00   CDA-BCA31-ATR
                  BIOASSAY: Anti-Candida albicans (MTCC 183)                 ATR         $250.00         $200.00      $175.00     $150.00     CDA-MA12-ATR
                  BIOASSAY: Anti-Escherichia coli (MTCC 1687)                ATR         $250.00         $200.00      $175.00     $150.00     CDA-MA03-ATR
                  BIOASSAY: Anti-Kleibsiella pnemoniae (MTCC 109)            ATR         $250.00         $200.00      $175.00     $150.00     CDA-MA04-ATR
                  BIOASSAY: Anti-Microsporum gypseum (MTCC 2819)             ATR         $325.00         $260.00      $227.50     $195.00     CDA-MA14-ATR
                  BIOASSAY: Anti-Propionibacterium acne (MTCC 1951)          ATR         $250.00         $200.00      $175.00     $150.00     CDA-MA08-ATR
                  BIOASSAY: Anti-Proteus vulgaris (MTCC 1771)                ATR         $250.00         $200.00      $175.00     $150.00     CDA-MA06-ATR
                  BIOASSAY: Anti-Pseudomonas aeruginosa (MTCC                ATR         $250.00         $200.00      $175.00     $150.00     CDA-MA05-ATR
                  1688)
Forms




                  BIOASSAY: Anti-S. mutans* (MTCC 890)                       ATR         $300.00         $240.00      $210.00     $180.00     CDA-MA09-ATR
                  BIOASSAY: Anti-S. salivarius (ATCC 13419-derived)          ATR         $300.00         $240.00      $210.00     $180.00     CDA-MA10-ATR


                                   Tel. (949) 419-0288             Fax. (949) 419-0294             email. sales@chromadex.com         www.chromadex.com
                                                                                                                                      27




                                                                                                                                           Introduction
                                                                                     Cost per Sample($)
SERVICE DESCRIPTION                                       Report 1 Sample 2-4     5-9     10+                          Service Code
                                                          Type            Samples Samples
BIOASSAY: Anti-S. sanguis (ATCC 10556-derived)            ATR    $300.00      $240.00        $210.00       $180.00     CDA-MA11-ATR
BIOASSAY: Anti-Staphylococcus aureus* (MTCC 737)          ATR    $250.00      $200.00        $175.00       $150.00     CDA-MA02-ATR
BIOASSAY: Anti-Staphylococcus epidermidis                 ATR    $250.00      $200.00        $175.00       $150.00     CDA-MA07-ATR
(MTCC435
BIOASSAY: Anti-Trichophyton rubrum (MTCC 296)             ATR    $325.00      $260.00        $227.50       $195.00     CDA-MA13-ATR
BIOASSAY: Apoptosis - DNA Fragmentation                   ATR    $700.00      $560.00        $490.00       $420.00     CDA-SPA03-ATR
BIOASSAY: Apoptsis - Caspase 3/7                          ATR    $700.00      $560.00        $490.00       $420.00     CDA-SPA04-ATR




                                                                                                                                           Validation
BIOASSAY: Apoptsis - Caspase 8                            ATR    $700.00      $560.00        $490.00       $420.00     CDA-SPA05-ATR
BIOASSAY: Apoptsis - Caspase 9                            ATR    $700.00      $560.00        $490.00       $420.00     CDA-SPA06-ATR
BIOASSAY: Aryl Sulphatase Inhibition Assay                ATR    $995.00      $796.00        $696.50       $597.00     CDA-BCA06-ATR
BIOASSAY: Beta - Glucuronidase Inhibition Assay           ATR    $495.00      $396.00        $346.50       $297.00     CDA-BCA03-ATR
BIOASSAY: Brine Shrimp Lethality Test++                   ATR    $99.00       $79.20         $69.30        $59.40      CDA-MA01-ATR
BIOASSAY: Butyrylcholinesterase Inhibition Assay*         ATR    $395.00      $316.00        $276.50       $237.00     CDA-BCA07-ATR
BIOASSAY: Ca++ Flux Assay for Endothelin Receptor         ATR    $1,000.00    $800.00        $700.00       $600.00     CDA-SPA08-ATR




                                                                                                                                            Example Reports
BIOASSAY: Caenorhabditis elegans Lethality                ATR    Call         Call           Call          Call        CDA-MA15-ATR
BIOASSAY: Caspase-3 inhibition Assay                      ATR    $795.00      $636.00        $556.50       $477.00     CDA-BCA30-ATR
BIOASSAY: Chromosomal aberration human lympho-            ATR    $4,990.00    $3,992.00      $3,493.00     $2,994.00   CDA-CA09-ATR
cytes
BIOASSAY: Collagen release NIH-3T3                        ATR    $3,895.00    $3,116.00      $2,726.50     $2,337.00   CDA-CA14-ATR
BIOASSAY: Collagenase Inhibition Assay                    ATR    $1,875.00    $1,500.00      $1,312.50     $1,125.00   CDA-BCA08-ATR
BIOASSAY: COX-II Inhibition Assay                         ATR    $1,550.00    $1,240.00      $1,085.00     $930.00     CDA-BCA24-ATR
BIOASSAY: COX-I Inhibition Assay                          ATR    $1,395.00    $1,116.00      $976.50       $837.00     CDA-BCA23-ATR
BIOASSAY: DPP IV Inhibition Assay                         ATR    $1,150.00    $920.00        $805.00       $690.00     CDA-BCA11-ATR
BIOASSAY: DPPH Assay*                                     ATR    $950.00      $760.00        $665.00       $570.00     CDA-BCA12-ATR
BIOASSAY: Elastase Inhibition Assay                       ATR    $1,150.00    $920.00        $805.00       $690.00     CDA-BCA13-ATR
BIOASSAY: Elastin Release Assay                           ATR    $1,875.00    $1,500.00      $1,312.50     $1,125.00   CDA-CA07-ATR




                                                                                                                                            Micro-Bio
BIOASSAY: Glucose-6-phosphatase                           ATR    $1,495.00    $1,196.00      $1,046.50     $897.00     CDA-BCA37-ATR
BIOASSAY: Hepatoprotection Assay using t-BH               ATR    $950.00      $760.00        $665.00       $570.00     CDA-CA06-ATR
BIOASSAY: Histamine Release Assay                         ATR    $2,950.00    $2,360.00      $2,065.00     $1,770.00   CDA-CA08-ATR
BIOASSAY: Hyaluronidase Inhibition Assay                  ATR    $1,250.00    $1,000.00      $875.00       $750.00     CDA-BCA14-ATR
BIOASSAY: Hydroxyl Radical Scavenging Assay               ATR    $825.00      $660.00        $577.50       $495.00     CDA-BCA15-ATR
BIOASSAY: IKK-Beta (NF-B kinase) inhibition (CALL)        ATR    $2,500.00    $2,000.00      $1,750.00     $1,500.00   CDA-BCA36-ATR
BIOASSAY: Insulin Release                                 ATR    $3,895.00    $3,116.00      $2,726.50     $2,337.00   CDA-CA13-ATR
BIOASSAY: Lipase Inhibition Assay                         ATR    $395.00      $316.00        $276.50       $237.00     CDA-BCA16-ATR
BIOASSAY: LTB4 Release Assay                              ATR    $1,995.00    $1,596.00      $1,396.50     $1,197.00   CDA-CA05-ATR




                                                                                                                                           Service List
BIOASSAY: Lymphocyte Proliferation Con A Assay            ATR    $1,375.00    $1,100.00      $962.50       $825.00     CDA-CA01C-ATR
BIOASSAY: Lymphocyte Proliferation LPS Assay              ATR    $1,375.00    $1,100.00      $962.50       $825.00     CDA-CA01A-ATR
BIOASSAY: Lymphocyte Proliferation PHA-L Assay            ATR    $1,375.00    $1,100.00      $962.50       $825.00     CDA-CA01B-ATR
BIOASSAY: Macrophage Phagocytosis                         ATR    $1,385.00    $1,108.00      $969.50       $831.00     CDA-CA04-ATR
BIOASSAY: Mechanism- Pseudomonas Quorum sens-             ATR    $250.00      $200.00        $175.00       $150.00     CDA-SPA11-ATR
ing
BIOASSAY: Melanin Release using B-16                      ATR    $4,990.00    $3,992.00      $3,493.00     $2,994.00   CDA-CA11-ATR
BIOASSAY: Methylene Blue - Cytotoxicity Assay             ATR    $250.00      $200.00        $175.00       $150.00     CDA-SPA02-ATR
BIOASSAY: Micronucleus Assay w/ human lymphocytes         ATR    $4,990.00    $3,992.00      $3,493.00     $2,994.00   CDA-CA10-ATR
BIOASSAY: MTS Cell Proliferation Assay                    ATR    $250.00      $200.00        $175.00       $150.00     CDA-SPA01-ATR
BIOASSAY: Nitric-oxide Scavenging Assay                   ATR    $550.00      $440.00        $385.00       $330.00     CDA-BCA09-ATR
                                                                                                                                            Forms




BIOASSAY: NO Release (in J774A.1 macrophages)             ATR    $1,625.00    $1,300.00      $1,137.50     $975.00     CDA-CA02-ATR
BIOASSAY: NO Scavenging (LPS prestim. macro-              ATR    $1,625.00    $1,300.00      $1,137.50     $975.00     CDA-CA03-ATR
phages)


      Tel. (949) 419-0288           Fax. (949) 419-0294         email. sales@chromadex.com             www.chromadex.com
                  28
Introduction
                                                                                                           Cost per Sample($)
                  SERVICE DESCRIPTION                                       Report 1 Sample 2-4     5-9     10+                              Service Code
                                                                            Type            Samples Samples
                  BIOASSAY: Nuclear Factor kappa B                          ATR         $1,000.00       $800.00      $700.00     $600.00     CDA-SPA09-ATR
                  BIOASSAY: ORAC and DPPH                                   ATR         $250.00         $200.00      $175.00     $150.00     CDA-SPA12-ATR
                  BIOASSAY: PAF Acetylhydrolase Inhibition Assay            ATR         $1,495.00       $1,196.00    $1,046.50   $897.00     CDA-BCA35-ATR
                  BIOASSAY: PARP Inhibition Assay                           ATR         $3,500.00       $2,800.00    $2,450.00   $2,100.00   CDA-BCA33-ATR
                  BIOASSAY: PGE2 release J774A.1 macrophage cells           ATR         $3,895.00       $3,116.00    $2,726.50   $2,337.00   CDA-CA12-ATR
                  BIOASSAY: Phosphodiesterase-I Inhibition Assay            ATR         $795.00         $636.00      $556.50     $477.00     CDA-BCA25-ATR
Validation




                  BIOASSAY: PLA2 Inhibition Assay                           ATR         $295.00         $236.00      $206.50     $177.00     CDA-BCA34-ATR
                  BIOASSAY: Prostaglandin E2                                ATR         $700.00         $560.00      $490.00     $420.00     CDA-SPA07-ATR
                  BIOASSAY: Protein Phosphatase-1 Inhibition Assay          ATR         $1,550.00       $1,240.00    $1,085.00   $930.00     CDA-BCA26-ATR
                  BIOASSAY: PTP-IB Inhibition Assay                         ATR         $2,195.00       $1,756.00    $1,536.50   $1,317.00   CDA-BCA21-ATR
                  BIOASSAY: RHO-Kinase (ROCK-II)                            ATR         $2,500.00       $2,000.00    $1,750.00   $1,500.00   CDA-BCA29-ATR
                  BIOASSAY: Superoxide Anion Scavenging Activity            ATR         $660.00         $528.00      $462.00     $396.00     CDA-BCA10-ATR
                  BIOASSAY: TC- PTPase Inhibition Assay                     ATR         $1,550.00       $1,240.00    $1,085.00   $930.00     CDA-BCA20-ATR
                  BIOASSAY: Thymidine phosphorylase Inhibition Assay        ATR         $395.00         $316.00      $276.50     $237.00     CDA-BCA28-ATR
Example Reports




                  BIOASSAY: Transcription Factor Nerf2 Phase 2 Enzy         ATR         $1,000.00       $800.00      $700.00     $600.00     CDA-SPA10-ATR
                  BIOASSAY: TROLOX Equiv. Antioxidant Cap Assay             ATR         $1,150.00       $920.00      $805.00     $690.00     CDA-BCA27-ATR
                  BIOASSAY: Trypsin Inhibition Assay                        ATR         $825.00         $660.00      $577.50     $495.00     CDA-BCA18-ATR
                  BIOASSAY: Tyrosinase Inhibition Assay                     ATR         $500.00         $400.00      $350.00     $300.00     CDA-BCA32-ATR
                  BIOASSAY: Xanthine Oxidase Inhibition Assay               ATR         $495.00         $396.00      $346.50     $297.00     CDA-BCA19-ATR
                  Bioluminex Contract Service                               ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100218-ARS
                  Bioluminex Contract Service                               ATR         $300.00         $240.00      $210.00     $180.00     CDA-00100218-ATR
                  Biotin - formula (w/sample clean up) by HPLC              ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100372-ARS
                  Biotin - formula (w/sample clean up) by HPLC              ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100372-ATR
                  Biotin - raw by HPLC                                      ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100076-ARS
                  Biotin - raw by HPLC                                      ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100076-ATR
                  Bitter Melon for Charantin by HPLC/MS                     ARS         $350.00         $280.00      $245.00     $210.00     CDA-00100112-ARS
Micro-Bio




                  Bitter Melon for Charantin by HPLC/MS                     ATR         $450.00         $360.00      $315.00     $270.00     CDA-00100112-ATR
                  Bitter Orange Analysis for Synephrine by HPLC             ARS         $250.00         $200.00      $175.00     $150.00     CDA-00002003-ARS
                  Bitter Orange Analysis for Synephrine by HPLC             ATR         $350.00         $280.00      $245.00     $210.00     CDA-00002003-ATR
                  Black Cohosh for Triterpenes by HPLC                      ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100113-ARS
                  Black Cohosh for Triterpenes by HPLC                      ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100113-ATR
                  Black Tea for Theaflavines by HPLC                         ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100141-ARS
                  Black Tea for Theaflavines by HPLC                         ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100141-ATR
                  Blue Vervain Identity Testing by Microscopy               ARS         $200.00         $160.00      $140.00     $120.00     CDA-00100026-ARS
Service List




                  Blue Vervain Identity Testing by TLC                      ARS         $200.00         $160.00      $140.00     $120.00     CDA-00100009-ARS
                  Blueberry Extract for Anthocyanidins by UV                ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100017-ARS
                  Blueberry Identity Testing by TLC                         ARS         $200.00         $160.00      $140.00     $120.00     CDA-00100062-ARS
                  Blueberry Leaf Extract Identity by TLC                    ARS         $200.00         $160.00      $140.00     $120.00     CDA-00100101-ARS
                  Blueberry Leaf Extract Identity by TLC                    ATR         $300.00         $240.00      $210.00     $180.00     CDA-00100101-ATR
                  Boswellia Analysis for Boswellic Acids by HPLC            ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100083-ARS
                  Boswellia Analysis for Boswellic Acids by HPLC            ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100083-ATR
                  Bupleurum Root Identity by TLC                            ATR         $300.00         $240.00      $210.00     $180.00     CDA-00100299-ATR
                  Burdock Identity Testing by TLC                           ARS         $200.00         $160.00      $140.00     $120.00     CDA-00100079-ARS
                  Butchers Broom for Saponins by HPLC                       ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100343-ARS
                  Butchers Broom for Saponins by HPLC                       ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100343-ATR
                  Butterbur for Pyrrolizidine Alkaloids by HPLC             ARS         $250.00         $200.00      $175.00     $150.00     CDA-00100333-ARS
Forms




                  Butterbur for Pyrrolizidine Alkaloids by HPLC             ATR         $350.00         $280.00      $245.00     $210.00     CDA-00100333-ATR
                  Butternut Bark Identity Testing by Microscopy             ARS         $200.00         $160.00      $140.00     $120.00     CDA-00100025-ARS


                                  Tel. (949) 419-0288             Fax. (949) 419-0294             email. sales@chromadex.com        www.chromadex.com
                                                                                                                                     29




                                                                                                                                           Introduction
                                                                                    Cost per Sample($)
SERVICE DESCRIPTION                                          Report 1 Sample 2-4     5-9     10+                        Service Code
                                                             Type            Samples Samples
Butternut Bark Identity Testing by TLC                       ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100008-ARS
Butternut Bark Identity Testing by TLC                       ATR    $300.00      $240.00        $210.00       $180.00   CDA-00100008-ATR
Caffeine Analysis by HPLC                                    ARS    $250.00      $200.00        $175.00       $150.00   CDA-00003001-ARS
Caffeine Analysis by HPLC                                    ATR    $350.00      $280.00        $245.00       $210.00   CDA-00003001-ATR
Calcium 4-Methyl-2-Oxovalerate by HPLC                       ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100150-ARS
Calcium by ICP                                               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100221-ARS
Calicum Folinate Analysis (Folinic Acid)                     ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100187-ATR




                                                                                                                                           Validation
Capsicum (Cayenne) Testing by HPLC                           ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100033-ARS
Capsicum (Cayenne) Testing by Microscopy                     ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100022-ARS
Capsule Fill Weight Determination                            ARS    $100.00      $80.00         $70.00        $60.00    CDA-00100386-ARS
Carnitine (L-) by HPLC                                       ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100075-ARS
Carnitine (L-) by HPLC                                       ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100075-ATR
Carotenoids by HPLC                                          ARS    $250.00      $200.00        $175.00       $150.00   CDA-00003003-ARS
Carotenoids by HPLC                                          ATR    $350.00      $280.00        $245.00       $210.00   CDA-00003003-ATR




                                                                                                                                            Example Reports
Cats Claw Analysis for Oxindole Alkaloids by HPLC            ARS    $250.00      $200.00        $175.00       $150.00   CDA-00003004-ARS
Cats Claw Analysis for Oxindole Alkaloids by HPLC            ATR    $350.00      $280.00        $245.00       $210.00   CDA-00003004-ATR
Cats Claw for Carboxy Alkyl Esters by UV                     ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100344-ARS
Cats Claw for Carboxy Alkyl Esters by UV                     ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100344-ATR
Cats Claw Identity by TLC                                    ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100345-ARS
Cats Claw Identity by TLC                                    ATR    $300.00      $240.00        $210.00       $180.00   CDA-00100345-ATR
Cayenne (Capsicum) Identity Testing by Microscopy            ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100108-ARS
Cayenne (Capsicum) Identity Testing by TLC                   ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100005-ARS
Cayenne (Capsicum) Identity Testing by TLC                   ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100005-ATR
Celery Seed for Flavonoids by HPLC                           ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100046-ARS
Celery Seed Identity Testing by Microscopy                   ARS    $225.00      $180.00        $157.50       $135.00   CDA-00100105-ARS
Celery Seed Identity Testing by TLC                          ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100045-ARS




                                                                                                                                            Micro-Bio
Celery Seed Identity Testing by TLC                          ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100045-ATR
Cetyl Myristoleate (CMO) by GC                               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100131-ARS
Cetyl Myristoleate (CMO) by GC                               ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100131-ATR
Chamomile Identity Testing by Microscopy                     ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100109-ARS
Chamomile Identity Testing by TLC                            ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100037-ARS
Chamomile Identity Testing by TLC                            ATR    $300.00      $240.00        $210.00       $180.00   CDA-00100037-ATR
Chelidonium for Alkaloids by HPLC                            ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100106-ARS
Chelidonium for Alkaloids by HPLC                            ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100106-ATR
Chicory Root Identity Testing by TLC                         ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100055-ARS




                                                                                                                                           Service List
Chicory Root Identity Testing by TLC                         ATR    $300.00      $240.00        $210.00       $180.00   CDA-00100055-ATR
Chloramphenacol Negative Screen                              ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100177-ARS
Chlorella for Identity by TLC                                ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100360-ARS
Chlorella for Identity by TLC                                ATR    $300.00      $240.00        $210.00       $180.00   CDA-00100360-ATR
Chondroitin Sulfate by CPC Titration                         ARS    $275.00      $220.00        $192.50       $165.00   CDA-00100216-ARS
Chondroitin Sulfate by CPC Titration                         ATR    $375.00      $300.00        $262.50       $225.00   CDA-00100216-ATR
Chondroitin Sulfate by HPLC (Enzymatic method)               ARS    $300.00      $240.00        $210.00       $180.00   CDA-00100327-ARS
Chondroitin Sulfate by HPLC (Enzymatic method)               ATR    $400.00      $320.00        $280.00       $240.00   CDA-00100327-ATR
Cinnamon Extract for Phenolic acids by GC                    ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100341-ARS
Cinnamon Extract for Phenolic acids by GC                    ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100341-ATR
Cinnamon for Coumarin by GC                                  ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100342-ARS
                                                                                                                                            Forms




Cinnamon for Coumarin by GC                                  ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100342-ATR
Citrullene Malleate Analysis                                 ARS    $250.00      $200.00        $175.00       $150.00   CDA-00003011-ARS


      Tel. (949) 419-0288              Fax. (949) 419-0294         email. sales@chromadex.com             www.chromadex.com
                  30
Introduction
                                                                                                         Cost per Sample($)
                  SERVICE DESCRIPTION                                     Report 1 Sample 2-4     5-9     10+                          Service Code
                                                                          Type            Samples Samples
                  Citrullene Malleate Analysis                            ATR         $350.00         $280.00      $245.00   $210.00   CDA-00003011-ATR
                  Citrus Bioflavonoids by HPLC                             ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100331-ARS
                  Citrus Bioflavonoids by HPLC                             ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100331-ATR
                  Citrus Liminoids (Limonin and Nomilin) by HPLC          ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100178-ARS
                  Coenzyme Q10 Analysis by HPLC                           ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100060-ARS
                  Coenzyme Q10 Analysis by HPLC                           ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100060-ATR
Validation




                  Coenzyme Q10 Cis-form Analysis by HPLC                  ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100283-ARS
                  Coenzyme Q10 Cis-form Analysis by HPLC                  ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100283-ATR
                  Coleus for Atropine and Scopolamine by HPLC             ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100162-ARS
                  Coleus for Atropine and Scopolamine by HPLC             ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100162-ATR
                  Coleus Forskohlii for Forskolin by HPLC                 ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100016-ARS
                  Coleus Forskohlii for Forskolin by HPLC                 ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100016-ATR
                  Coleus Forskohlii for Forskolin by TLC                  ATR         $300.00         $240.00      $210.00   $180.00   CDA-00100281-ATR
                  Cordycepin by HPLC                                      ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100136-ARS
Example Reports




                  Cordycepin by HPLC                                      ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100136-ATR
                  Cordyceptic Acid by HPLC                                ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100137-ARS
                  Creatine by HPLC/UV                                     ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100156-ARS
                  Creatine by HPLC/UV                                     ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100156-ATR
                  Creatine Ethyl Ester Analysis by HPLC                   ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100129-ARS
                  Creatine Ethyl Ester Analysis by HPLC                   ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100129-ATR
                  Creatinine Screen by HPLC/MS                            ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100157-ARS
                  Creatinine Screen by HPLC/MS                            ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100157-ATR
                  Creatinol-O-Phosphate by HPLC                           ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100266-ARS
                  Creatinol-O-Phosphate by HPLC                           ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100266-ATR
                  Customer Method by HPLC                                 ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100159-ARS
                  Customer Method by HPLC                                 ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100159-ATR
Micro-Bio




                  Cystine by HPLC                                         ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100351-ARS
                  Cystine by HPLC                                         ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100351-ATR
                  Dandelion Root Identity Testing by TLC                  ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100049-ARS
                  Dandelion Root Identity Testing by TLC                  ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100049-ATR
                  Devils Claw Powder by TLC                               ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100225-ARS
                  DHEA Testing by HPLC                                    ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100279-ARS
                  Dicreatine Malate by HPLC/MS                            ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100146-ARS
                  Dicreatine Malate by HPLC/MS                            ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100146-ATR
Service List




                  Dicreatine Sulfate Analysis by HPLC                     ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100248-ARS
                  Dicreatine Sulfate Analysis by HPLC                     ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100248-ATR
                  Dicreatinol Sulfate by HPLC                             ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100305-ARS
                  Dietary Fiber Analysis (Total)                          ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100306-ARS
                  Direct Infusion Mass Spec Analysis                      ARS         $100.00         $80.00       $70.00    $60.00    CDA-00100138-ARS
                  Dissociation Constant Determination                     ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100249-ATR
                  Dong Quai for Ligustilide by HPLC                       ARS         $250.00         $200.00      $175.00   $150.00   CDA-00004002-ARS
                  Dong Quai for Ligustilide by HPLC                       ATR         $350.00         $280.00      $245.00   $210.00   CDA-00004002-ATR
                  Dong Quai Identity by TLC                               ARS         $225.00         $180.00      $157.50   $135.00   CDA-00100170-ARS
                  Ecdysterone by HPLC                                     ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100241-ARS
                  Echinacea for Isobutylamides by HPLC                    ARS         $300.00         $240.00      $210.00   $180.00   CDA-00005006-ARS
                  Echinacea for Isobutylamides by HPLC                    ATR         $400.00         $320.00      $280.00   $240.00   CDA-00005006-ATR
Forms




                  Echinacea for Phenolic acids by HPLC                    ARS         $250.00         $200.00      $175.00   $150.00   CDA-00005001-ARS
                  Echinacea for Phenolic acids by HPLC                    ATR         $350.00         $280.00      $245.00   $210.00   CDA-00005001-ATR


                                   Tel. (949) 419-0288          Fax. (949) 419-0294             email. sales@chromadex.com      www.chromadex.com
                                                                                                                                       31




                                                                                                                                             Introduction
                                                                                      Cost per Sample($)
SERVICE DESCRIPTION                                            Report 1 Sample 2-4     5-9     10+                        Service Code
                                                               Type            Samples Samples




                                                                                                                                              ntrod
Echinacea Identity by TLC                                      ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100089-ARS
Elemental Analysis on C,H,N and P                              ATR    $275.00      $220.00        $192.50       $165.00   CDA-00100116-ATR
Eleuthero (Siberian Ginseng) Identity by TLC                   ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100310-ARS
Eleuthero (Siberian Ginseng) Identity by TLC                   ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100310-ATR
Eleutherococcus for Eleutherosides by HPLC                     ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100047-ARS
Ephedrine Alkaloids by HPLC                                    ARS    $250.00      $200.00        $175.00       $150.00   CDA-00005003-ARS
Ephedrine Alkaloids by HPLC                                    ATR    $350.00      $280.00        $245.00       $210.00   CDA-00005003-ATR




                                                                                                                                             Validation
Epimedium (Horny Goat Weed) for Icariin by HPLC                ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100099-ARS
Epimedium (Horny Goat Weed) for Icariin by HPLC                ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100099-ATR




                                                                                                                                             Valida
Essential Oils by GC                                           ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100278-ARS
Essential Oils by GC                                           ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100278-ATR
Eucalyptus for Eucalyptol by GC                                ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100122-ARS
Eucalyptus for Eucalyptol by GC                                ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100122-ATR
Eurycoma longifolia (Tongkat ali) by HPLC                      ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100160-ATR




                                                                                                                                              Example Reports
Eurypeptides in Eurycoma by BCA method                         ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100285-ARS
Eurypeptides in Eurycoma by BCA method                         ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100285-ATR
Evodia for Evodiamine by HPLC                                  ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100096-ARS
Evodia for Evodiamine by HPLC                                  ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100096-ATR
Eyebright Analysis for Aucubin by HPLC                         ARS    $250.00      $200.00        $175.00       $150.00   CDA-00005007-ATR
Eyebright Analysis for Aucubin by HPLC                         ATR    $350.00      $280.00        $245.00       $210.00   CDA-00005007-ARS
Fatty Acid (Total) Analysis by GC                              ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100332-ARS
Fatty Acid (Total) Analysis by GC                              ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100332-ATR
Fatty Acid (Total) including EPA/DHA by GC                     ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100222-ARS
Fatty Acid (Total) including EPA/DHA by GC                     ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100222-ATR
Fenugreek for 4-Hydroxyisoleucine by HPLC                      ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100044-ARS
Fenugreek for 4-Hydroxyisoleucine by HPLC                      ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100044-ATR




                                                                                                                                              Micro-Bio
Fenugreek Identity Testing by TLC                              ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100038-ARS
Fenugreek Identity Testing by TLC                              ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100038-ATR
Feverfew Analysis for Parthenolide by HPLC                     ARS    $250.00      $200.00        $175.00       $150.00   CDA-00006002-ARS
Feverfew Analysis for Parthenolide by HPLC                     ATR    $350.00      $280.00        $245.00       $210.00   CDA-00006002-ATR
Fish Oil for Fatty acids by GC                                 ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100125-ARS
Fish Oil for Fatty acids by GC                                 ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100125-ATR
Fish Oil for Rancidity-Anisidine level                         ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100205-ATR
Flavonoids (Misc) by HPLC                                      ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100293-ARS
Flavopereirine by HPLC                                         ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100175-ARS




                                                                                                                                             Service List
Flavopereirine by HPLC                                         ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100175-ATR
Flax Seed for Lignans - SDG by HPLC                            ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100064-ARS
Flax Seed for Lignans - SDG by HPLC                            ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100064-ATR
Folic Acid (Vitamin M) (w/sample clean up) by HPLC             ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100267-ARS
Folic Acid (Vitamin M) (w/sample clean up) by HPLC             ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100267-ATR
Fucoidin Analysis                                              ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100275-ARS
Furocoumarins in Citrus Oils by HPLC                           ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100315-ARS
Furocoumarins in Citrus Oils by HPLC                           ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100315-ATR
GABA by HPLC                                                   ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100309-ARS
GABA by HPLC                                                   ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100309-ATR
GaKIC Analysis by HPLC                                         ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100247-ARS
                                                                                                                                              Forms




Garcinia for Hydroxycitric Acid (HCA) by HPLC                  ARS    $250.00      $200.00        $175.00       $150.00   CDA-00007001-ARS
Garcinia for Hydroxycitric Acid (HCA) by HPLC                  ATR    $350.00      $280.00        $245.00       $210.00   CDA-00007001-ATR


      Tel. (949) 419-0288                Fax. (949) 419-0294            il. sales@chromadex.com
                                                                     email. sales@ch                        www.chromadex.com
                                                                                                                                   33




                                                                                                                                         Introduction
                                                                                   Cost per Sample($)
SERVICE DESCRIPTION                                        Report 1 Sample 2-4     5-9     10+                        Service Code
                                                           Type            Samples Samples
Green Coffee for Chlorogenic acids by HPLC                 ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100223-ATR
Green Coffee Identity by TLC                               ARS    $200.00       $160.00       $140.00       $120.00   CDA-00010319-ARS
Green Coffee Identity by TLC                               ATR    $300.00       $240.00       $210.00       $180.00   CDA-00100319-ATR
Green Tea for Catechins by HPLC                            ARS    $250.00       $200.00       $175.00       $150.00   CDA-00007010-ARS
Green Tea for Catechins by HPLC                            ATR    $350.00       $280.00       $245.00       $210.00   CDA-00007010-ATR
Green Tea Identity Testing by TLC                          ARS    $200.00       $160.00       $140.00       $120.00   CDA-00100004-ARS
Guarana Identity Testing by TLC                            ARS    $200.00       $160.00       $140.00       $120.00   CDA-00100272-ARS




                                                                                                                                         Validation
Guggul for Guggulsterones by HPLC                          ARS    $250.00       $200.00       $175.00       $150.00   CDA-00007011-ARS
Guggul for Guggulsterones by HPLC                          ATR    $350.00       $280.00       $245.00       $210.00   CDA-00007011-ATR
Gymnema for Gymnemagenin by HPLC                           ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100121-ARS
Gymnema for Gymnemagenin by HPLC                           ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100121-ATR
Hawthorn Identity by TLC                                   ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100300-ATR
Heavy Metals by AA                                         ARS    $99.00        $79.20        $69.30        $59.40    CDA-00100262-ARS
Hibiscus Identity Testing by Microscopy                    ARS    $225.00       $180.00       $157.50       $135.00   CDA-00100035-ARS




                                                                                                                                          Example Reports
Hibiscus Identity Testing by TLC                           ARS    $200.00       $160.00       $140.00       $120.00   CDA-00100034-ARS
Hibiscus Identity Testing by TLC                           ATR    $300.00       $240.00       $210.00       $180.00   CDA-00100034-ATR
Histidine by HPLC                                          ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100353-ARS
Histidine by HPLC                                          ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100353-ATR
Holy Basil For Eugenol and Caryophyllene by GC             ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100189-ARS
Holy Basil For Eugenol and Caryophyllene by GC             ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100189-ATR
Holy Basil for Phenolic acids by HPLC                      ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100155-ARS
Holy Basil for Phenolic acids by HPLC                      ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100155-ATR
Holy Basil Ursolic Acid and Oleanolic Acid by HPLC         ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100098-ARS
Holy Basil Ursolic Acid and Oleanolic Acid by HPLC         ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100098-ATR
Honokiol Analysis by HPLC                                  ARS    $250.00       $200.00       $175.00       $150.00   CDA-00022002-ARS
Honokiol Analysis by HPLC                                  ATR    $350.00       $280.00       $245.00       $210.00   CDA-00022002-ATR




                                                                                                                                          Micro-Bio
Hoodia by Microscopy                                       ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100243-ARS
Hoodia Identity Testing for Fingerprint by TLC             ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100217-ARS
Hoodia Identity Testing for Fingerprint by TLC             ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100217-ATR
Hoodia Identity Testing for P57 by HPLC                    ARS    $350.00       $280.00       $245.00       $210.00   CDA-00100139-ARS
Hoodia Identity Testing for P57 by HPLC                    ATR    $450.00       $360.00       $315.00       $270.00   CDA-00100139-ATR
Hops for Bitter Acids by HPLC                              ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100173-ARS
Hops for Bitter Acids by HPLC                              ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100173-ATR
Hops Identity by TLC                                       ARS    $200.00       $160.00       $140.00       $120.00   CDA-00100172-ARS
Hops Identity by TLC                                       ATR    $300.00       $240.00       $210.00       $180.00   CDA-00100172-ATR




                                                                                                                                         Service List
Hyaluronic Acid by HPLC                                    ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100086-ARS
Hydroxyproline by HPLC                                     ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100085-ARS
Hydroxyproline by HPLC                                     ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100085-ATR
ICP-MS Full Panel (66 Elements)                            ARS    $450.00       $360.00       $315.00       $270.00   CDA-00100069-ARS
ICP-MS/ICP-OES for Single Element                          ARS    Call          Call          Call          Call      CDA-00100245-ARS
Iodine Analysis by ICP-MS                                  ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100336-ARS
IR Fingerprint Assay                                       ARS    $50.00        $40.00        $35.00        $30.00    CDA-00009005-ARS
IR Fingerprint Assay                                       ATR    $150.00       $120.00       $105.00       $90.00    CDA-00009005-ATR
Irish Moss Identity by Microscopy                          ARS    $200.00       $160.00       $140.00       $120.00   CDA-00100021-ARS
Irish Moss Identity Testing by TLC                         ARS    $200.00       $160.00       $140.00       $120.00   CDA-00100006-ARS
Isoleucine by HPLC                                         ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100354-ATR
                                                                                                                                          Forms




Ivy (Hedera Helix) for Hederacoside by HPLC                ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100325-ARS
Ivy (Hedera Helix) for Hederacoside by HPLC                ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100325-ATR


     Tel. (949) 419-0288             Fax. (949) 419-0294         email. sales@chromadex.com             www.chromadex.com
                                                                                                                                   33




                                                                                                                                         Introduction
                                                                                   Cost per Sample($)
SERVICE DESCRIPTION                                        Report 1 Sample 2-4     5-9     10+                        Service Code
                                                           Type            Samples Samples
Green Coffee for Chlorogenic acids by HPLC                 ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100223-ATR
Green Coffee Identity by TLC                               ARS    $200.00       $160.00       $140.00       $120.00   CDA-00010319-ARS
Green Coffee Identity by TLC                               ATR    $300.00       $240.00       $210.00       $180.00   CDA-00100319-ATR
Green Tea for Catechins by HPLC                            ARS    $250.00       $200.00       $175.00       $150.00   CDA-00007010-ARS
Green Tea for Catechins by HPLC                            ATR    $350.00       $280.00       $245.00       $210.00   CDA-00007010-ATR
Green Tea Identity Testing by TLC                          ARS    $200.00       $160.00       $140.00       $120.00   CDA-00100004-ARS
Guarana Identity Testing by TLC                            ARS    $200.00       $160.00       $140.00       $120.00   CDA-00100272-ARS




                                                                                                                                         Validation
Guggul for Guggulsterones by HPLC                          ARS    $250.00       $200.00       $175.00       $150.00   CDA-00007011-ARS
Guggul for Guggulsterones by HPLC                          ATR    $350.00       $280.00       $245.00       $210.00   CDA-00007011-ATR
Gymnema for Gymnemagenin by HPLC                           ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100121-ARS
Gymnema for Gymnemagenin by HPLC                           ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100121-ATR
Hawthorn Identity by TLC                                   ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100300-ATR
Heavy Metals by AA                                         ARS    $99.00        $79.20        $69.30        $59.40    CDA-00100262-ARS
Hibiscus Identity Testing by Microscopy                    ARS    $225.00       $180.00       $157.50       $135.00   CDA-00100035-ARS




                                                                                                                                          Example Reports
Hibiscus Identity Testing by TLC                           ARS    $200.00       $160.00       $140.00       $120.00   CDA-00100034-ARS
Hibiscus Identity Testing by TLC                           ATR    $300.00       $240.00       $210.00       $180.00   CDA-00100034-ATR
Histidine by HPLC                                          ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100353-ARS
Histidine by HPLC                                          ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100353-ATR
Holy Basil For Eugenol and Caryophyllene by GC             ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100189-ARS
Holy Basil For Eugenol and Caryophyllene by GC             ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100189-ATR
Holy Basil for Phenolic acids by HPLC                      ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100155-ARS
Holy Basil for Phenolic acids by HPLC                      ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100155-ATR
Holy Basil Ursolic Acid and Oleanolic Acid by HPLC         ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100098-ARS
Holy Basil Ursolic Acid and Oleanolic Acid by HPLC         ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100098-ATR
Honokiol Analysis by HPLC                                  ARS    $250.00       $200.00       $175.00       $150.00   CDA-00022002-ARS
Honokiol Analysis by HPLC                                  ATR    $350.00       $280.00       $245.00       $210.00   CDA-00022002-ATR




                                                                                                                                          Micro-Bio
Hoodia by Microscopy                                       ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100243-ARS
Hoodia Identity Testing for Fingerprint by TLC             ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100217-ARS
Hoodia Identity Testing for Fingerprint by TLC             ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100217-ATR
Hoodia Identity Testing for P57 by HPLC                    ARS    $350.00       $280.00       $245.00       $210.00   CDA-00100139-ARS
Hoodia Identity Testing for P57 by HPLC                    ATR    $450.00       $360.00       $315.00       $270.00   CDA-00100139-ATR
Hops for Bitter Acids by HPLC                              ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100173-ARS
Hops for Bitter Acids by HPLC                              ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100173-ATR
Hops Identity by TLC                                       ARS    $200.00       $160.00       $140.00       $120.00   CDA-00100172-ARS
Hops Identity by TLC                                       ATR    $300.00       $240.00       $210.00       $180.00   CDA-00100172-ATR




                                                                                                                                         Service List
Hyaluronic Acid by HPLC                                    ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100086-ARS
Hydroxyproline by HPLC                                     ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100085-ARS
Hydroxyproline by HPLC                                     ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100085-ATR
ICP-MS Full Panel (66 Elements)                            ARS    $450.00       $360.00       $315.00       $270.00   CDA-00100069-ARS
ICP-MS/ICP-OES for Single Element                          ARS    Call          Call          Call          Call      CDA-00100245-ARS
Iodine Analysis by ICP-MS                                  ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100336-ARS
IR Fingerprint Assay                                       ARS    $50.00        $40.00        $35.00        $30.00    CDA-00009005-ARS
IR Fingerprint Assay                                       ATR    $150.00       $120.00       $105.00       $90.00    CDA-00009005-ATR
Irish Moss Identity by Microscopy                          ARS    $200.00       $160.00       $140.00       $120.00   CDA-00100021-ARS
Irish Moss Identity Testing by TLC                         ARS    $200.00       $160.00       $140.00       $120.00   CDA-00100006-ARS
Isoleucine by HPLC                                         ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100354-ATR
                                                                                                                                          Forms




Ivy (Hedera Helix) for Hederacoside by HPLC                ARS    $250.00       $200.00       $175.00       $150.00   CDA-00100325-ARS
Ivy (Hedera Helix) for Hederacoside by HPLC                ATR    $350.00       $280.00       $245.00       $210.00   CDA-00100325-ATR


     Tel. (949) 419-0288             Fax. (949) 419-0294         email. sales@chromadex.com             www.chromadex.com
                  34
Introduction
                                                                                                           Cost per Sample($)
                  SERVICE DESCRIPTION                                       Report 1 Sample 2-4     5-9     10+                          Service Code
                                                                            Type            Samples Samples
                  Jojoba for Simmondsin by HPLC                             ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100291-ARS
                  Jojoba for Simmondsin by HPLC                             ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100291-ATR
                  Kava Kava Analysis for Kavalactones by HPLC               ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100063-ARS
                  Kava Kava Analysis for Kavalactones by HPLC               ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100063-ATR
                  Kelp Identity Testing by Microscopy                       ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100023-ARS
                  Kelp Identity Testing by TLC                              ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100013-ARS
Validation




                  Kelp Identity Testing by TLC                              ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100013-ATR
                  Kudzu Analysis for Isoflavones by HPLC                     ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100328-ARS
                  Kudzu Analysis for Isoflavones by HPLC                     ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100328-ATR
                  Lactose by GC                                             ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100308-ARS
                  Lawsone Analysis by HPLC                                  ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100077-ARS
                  LC-MS Fingerprint                                         ARS         $350.00         $280.00      $245.00   $210.00   CDA-00100104-ARS
                  LC-MS Fingerprint                                         ATR         $550.00         $440.00      $385.00   $330.00   CDA-00100104-ATR
                  Lecithin by HPLC                                          ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100294-ARS
Example Reports




                  Lemon for Limonene by GC                                  ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100132-ARS
                  Leucine by HPLC                                           ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100208-ARS
                  Leucine by HPLC                                           ATR         $350.00         $280.00      $245.00   $210.00   CDA-000100208-ATR
                  Licorice for Glycyrrhizic Acid by HPLC                    ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100054-ARS
                  Licorice for Glycyrrhizic Acid by HPLC                    ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100054-ATR
                  Licorice Identity by TLC                                  ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100007-ARS
                  Licorice Identity by TLC                                  ATR         $300.00         $240.00      $210.00   $180.00   CDA-00100007-ATR
                  Licorice (Glycyrrhiza) Identity by Microscopy             ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100024-ARS
                  Linoleic Acid by HPLC                                     ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100196-ARS
                  Lipoic Acid, DL-Alpha by HPLC                             ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100126-ARS
                  Lipoic Acid, DL-Alpha by HPLC                             ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100126-ATR
                  Lupeol Analysis by GC                                     ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100164-ARS
Micro-Bio




                  Lupeol Analysis by GC                                     ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100164-ATR
                  Lutein and Zeaxanthin Testing by HPLC                     ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100191-ARS
                  Lutein and Zeaxanthin Testing by HPLC                     ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100191-ATR
                  Lycopene by HPLC                                          ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100296-ARS
                  Lycopene by HPLC                                          ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100296-ATR
                  Lysine by HPLC                                            ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100355-ARS
                  Lysine by HPLC                                            ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100355-ATR
                  Maca Identity Testing by TLC                              ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100078-ARS
Service List




                  Maca Isothiocyanates by HPLC                              ARS         $300.00         $240.00      $210.00   $180.00   CDA-00100303-ARS
                  Maca Isothiocyanates by HPLC                              ATR         $400.00         $320.00      $280.00   $240.00   CDA-00100303-ATR
                  Magnesium by ICP                                          ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100307-ARS
                  Magnolia Analysis for Honokiol/Magnolol by HPLC           ARS         $250.00         $200.00      $175.00   $150.00   CDA-00013004-ARS
                  Magnolia Analysis for Honokiol/Magnolol by HPLC           ATR         $350.00         $280.00      $245.00   $210.00   CDA-00013004-ATR
                  Maitake Mushroom for Polysaccharides                      ARS         $275.00         $220.00      $192.50   $165.00   CDA-00100119-ARS
                  Malate (Malic Acid) by HPLC/UV                            ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100158-ARS
                  Malate (Malic Acid) by HPLC/UV                            ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100158-ATR
                  Mangosteen for Mangostin Xanthones by HPLC                ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100084-ARS
                  Mangosteen for Mangostin Xanthones by HPLC                ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100084-ATR
                  Marigold for Lutein by HPLC                               ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100183-ARS
                  Meadowsweet Identity by TLC                               ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100298-ARS
Forms




                  Melatonin by HPLC                                         ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100229-ARS
                  Melatonin by HPLC                                         ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100229-ATR


                                   Tel. (949) 419-0288            Fax. (949) 419-0294             email. sales@chromadex.com      www.chromadex.com
                                                                                                                                      35




                                                                                                                                            Introduction
                                                                                     Cost per Sample($)
SERVICE DESCRIPTION                                           Report 1 Sample 2-4     5-9     10+                        Service Code
                                                              Type            Samples Samples
Melting Point                                                 ARS    $100.00      $80.00         $70.00        $60.00    CDA-00100067-ARS
Methionine by HPLC                                            ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100356-ARS
Methionine by HPLC                                            ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100356-ATR
Method Development for Customer Sample by GC                  ARS    $750.00      $600.00        $525.00       $450.00   CDA-00100228-ARS
MICROBIOLOGICAL: Coliform - E. Coli Count                     ARS    $95.00       $76.00         $66.50        $57.00    CDA-00100252-ARS
MICROBIOLOGICAL: E-Coli 0157:H7                               ARS    $100.00      $80.00         $70.00        $60.00    CDA-00100348-ARS
MICROBIOLOGICAL: Enterobacteriaceae                           ARS    $65.00       $52.00         $45.50        $39.00    CDA-00100347-ARS




                                                                                                                                            Validation
MICROBIOLOGICAL: Full Panel                                   ARS    $155.00      $124.00        $108.50       $93.00    CDA-00100254-ARS
MICROBIOLOGICAL: Listeria                                     ARS    $65.00       $52.00         $45.50        $39.00    CDA-00100256-ARS
MICROBIOLOGICAL: Pseudomonas                                  ARS    $55.00       $44.00         $38.50        $33.00    CDA-00100257-ARS
MICROBIOLOGICAL: Salmonella Count                             ARS    $65.00       $52.00         $45.50        $39.00    CDA-00100255-ARS
MICROBIOLOGICAL: Staph aureus Count                           ARS    $65.00       $52.00         $45.50        $39.00    CDA-00100253-ARS
MICROBIOLOGICAL: Total Aerobic Plate Count                    ARS    $45.00       $36.00         $31.50        $27.00    CDA-00100087-ARS
MICROBIOLOGICAL: Total Yeast and Mold Count                   ARS    $45.00       $36.00         $31.50        $27.00    CDA-00100251-ARS




                                                                                                                                             Example Reports
Milk Thistle Analysis for Silymarin by HPLC                   ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100339-ARS
Milk Thistle Analysis for Silymarin by HPLC                   ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100339-ATR
Momordica for Charantin by HPLC                               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100124-ARS
Mushroom Extract for Agaric Acid by HPLC                      ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100234-ARS
Mushroom Extract for Agaric Acid by HPLC                      ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100234-ATR
Mushroom Extract for Betulinic acid by HPLC                   ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100235-ATR
Navajo Tea (Thelesperma) by TLC                               ATR    $200.00      $160.00        $140.00       $120.00   CDA-00100292-ATR
Negative Sildenafil (and other analogs) by HPLC                ARS    $650.00      $520.00        $455.00       $390.00   CDA-00100334-ARS
Negative Sildenafil (and other analogs) by HPLC                ATR    $750.00      $600.00        $525.00       $450.00   CDA-00100334-ATR
Neohesperidin Dihydrochalcone by HPLC                         ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100282-ARS
Nettle Extract for Silica by IC                               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100326-ARS
Nettle Identity Testing by Microscopy                         ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100058-ARS




                                                                                                                                             Micro-Bio
Nettle Identity Testing by TLC                                ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100010-ARS
Nettle Identity Testing by TLC                                ATR    $300.00      $240.00        $210.00       $180.00   CDA-00100010-ATR
Nettle Root for Scopoletin by HPLC                            ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100288-ARS
Niacin (Bound and Free) Activity Assay                        ARS    $130.00      $104.00        $91.00        $78.00    CDA-00100273-ARS
Nicotine Content by HPLC                                      ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100271-ATR
NLEA Abbreviated Nutrient Package                             ARS    $795.00      $636.00        $556.50       $477.00   CDA-00100088-ARS
NLEA Mandatory Nutritional Labeling Package                   ARS    $1,350.00    $1,080.00      $945.00       $810.00   CDA-00100179-ARS
NMR With C13 and Proton                                       ATR    $550.00      $440.00        $385.00       $330.00   CDA-00100115-ATR
Noni for Identity Testing by TLC                              ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100227-ARS




                                                                                                                                            Service List
Norvaline by HPLC                                             ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100366-ARS
Norvaline by HPLC                                             ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100366-ATR
Octopamine HCL by HPLC                                        ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100135-ATR
Olive Leaf Analysis for Oleuropein by HPLC                    ARS    $250.00      $200.00        $175.00       $150.00   CDA-00015002-ARS
Olive Leaf Analysis for Oleuropein by HPLC                    ATR    $350.00      $280.00        $245.00       $210.00   CDA-00015002-ATR
Optical Rotation (Specific)                                    ARS    $165.00      $132.00        $115.50       $99.00    CDA-00100068-ARS
Organic acids by HPLC                                         ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100338-ARS
Organic acids by HPLC                                         ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100338-ATR
Ornithine by HPLC                                             ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100370-ARS
Ornithine by HPLC                                             ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100370-ATR
Pantethine Analysis by CE                                     ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100280-ARS
                                                                                                                                             Forms




Pantothenic Acid (Vitamin B5) by HPLC                         ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100193-ARS
Pao Pereira for Alstonine and Flavopereirine HPLC             ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100244-ARS


      Tel. (949) 419-0288               Fax. (949) 419-0294         email. sales@chromadex.com             www.chromadex.com
                  36
Introduction
                                                                                                         Cost per Sample($)
                  SERVICE DESCRIPTION                                     Report 1 Sample 2-4     5-9     10+                          Service Code
                                                                          Type            Samples Samples
                  Pao Pereira for Alstonine and Flavopereirine HPLC       ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100244-ATR
                  Passion Flower for Flavonoids by HPLC                   ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100043-ARS
                  Passion Flower Identity Testing by TLC                  ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100042-ARS
                  Passion Flower Identity Testing by TLC                  ATR         $300.00         $240.00      $210.00   $180.00   CDA-00100042-ATR
                  PCBs Testing by GC                                      ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100323-ARS
                  Pesticide Screening Panel CDFA                          ARS         $510.00         $408.00      $357.00   $306.00   CDA-00100316-ARS
Validation




                  Petrolatum by GC                                        ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100123-ATR
                  PH level testing                                        ARS         $50.00          $40.00       $35.00    $30.00    CDA-00100074-ARS
                  Phenylalanine, DL- Analysis by Chiral HPLC              ARS         $300.00         $240.00      $210.00   $180.00   CDA-00100181-ARS
                  Phenylalanine, DL- Analysis by Chiral HPLC              ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100181-ATR
                  Phosphatidyl Serine by HPLC                             ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100127-ARS
                  Phosphatidyl Serine by HPLC                             ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100127-ATR
                  Phytosterol Analysis by GC                              ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100233-ARS
                  Phytosterol Analysis by GC                              ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100233-ATR
Example Reports




                  Phytosterol Analysis by HPLC                            ARS         $250.00         $200.00      $175.00   $150.00   CDA-00016004-ARS
                  Phytosterol Analysis by HPLC                            ATR         $350.00         $280.00      $245.00   $210.00   CDA-00016004-ATR
                  Picrorhiza Kurroa Identity by TLC                       ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100304-ARS
                  Pine Bark Identity Testing by TLC                       ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100250-ARS
                  Pine Bark Identity Testing by TLC                       ATR         $300.00         $240.00      $210.00   $180.00   CDA-00100250-ATR
                  Piperine in Pepper by HPLC                              ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100290-ARS
                  Piperine in Pepper by HPLC                              ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100290-ATR
                  Policosanol for Fatty Acids (C15:C34) by GC             ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100215-ARS
                  Policosanol for Fatty Acids (C15:C34) by GC             ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100215-ATR
                  Policosanol for Fatty Alcohols by GC                    ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100091-ARS
                  Policosanol for Fatty Alcohols by GC                    ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100091-ATR
                  Polyphenols (Total) by Folin C Method                   ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100224-ARS
Micro-Bio




                  Polyphenols (Total) by Folin C Method                   ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100224-ATR
                  Polyphenols by HPLC                                     ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100192-ARS
                  Polysaccharides - Beta-Glucans AOAC Method              ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100210-ARS
                  Polysaccharides - Beta-Glucans AOAC Method              ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100210-ATR
                  Pomegranate for Ellagic Acid by HPLC                    ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100120-ARS
                  Pomegranate for Ellagic Acid by HPLC                    ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100120-ATR
                  Pomegranate Identity Testing by TLC                     ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100052-ARS
                  Pomegranate Identity Testing by TLC                     ATR         $300.00         $240.00      $210.00   $180.00   CDA-00100052-ATR
Service List




                  Pomegranate Identity Testing by UV Spec                 ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100053-ARS
                  Potato for Glyco-Alkloids by HPLC                       ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100110-ARS
                  Potato for Glyco-Alkloids by HPLC                       ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100110-ATR
                  Procyanidins by HPLC                                    ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100167-ARS
                  Proline by HPLC                                         ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100357-ARS
                  Proline by HPLC                                         ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100357-ATR
                  Protein Content by BCA method                           ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100312-ARS
                  Protein content by Lowery Method                        ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100313-ARS
                  Protein content by Lowery Method                        ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100313-ATR
                  Protein (Total) by Combustion                           ARS         $49.50          $39.60       $34.65    $29.70    CDA-00100220-ARS
                  Prune Extract for Anthocyanidins by UV                  ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100020-ARS
                  Prune Extract Identity Testing by TLC                   ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100036-ARS
Forms




                  Prune Extract Identity Testing by TLC                   ATR         $300.00         $240.00      $210.00   $180.00   CDA-00100036-ATR
                  Pygeum for Phytosterols by GC                           ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100031-ARS


                                     Tel. (949) 419-0288        Fax. (949) 419-0294             email. sales@chromadex.com      www.chromadex.com
                                                                                                                                     37




                                                                                                                                           Introduction
                                                                                    Cost per Sample($)
SERVICE DESCRIPTION                                          Report 1 Sample 2-4     5-9     10+                        Service Code
                                                             Type            Samples Samples
Pygeum for Phytosterols by GC                                ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100031-ATR
Pygeum for Triterpenes by HPLC                               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100340-ARS
Pygeum for Triterpenes by HPLC                               ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100340-ATR
Pyridoxal-5-phosphate (Vitamin B6) by HPLC                   ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100095-ARS
Pyridoxal-5-phosphate (Vitamin B6) by HPLC                   ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100095-ATR
Pyrrolizidine Alkaloids by TLC                               ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100240-ARS
Pyrrolizidine Alkaloids by TLC                               ATR    $300.00      $240.00        $210.00       $180.00   CDA-00100240-ATR




                                                                                                                                           Validation
Quassia for Quassins by HPLC                                 ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100287-ARS
Quassia for Quassins by HPLC                                 ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100287-ATR
Rauwolfia Identity Testing by TLC                             ATR    $200.00      $160.00        $140.00       $120.00   CDA-00100201-ATR
Rauwolfia Testing by HPLC                                     ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100070-ATR
Rauwolfia Testing by HPLC                                     ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100070-ARS
RCRA 8 Metals Panel by ICP                                   ARS    $255.00      $204.00        $178.50       $153.00   CDA-00100314-ARS
Red Clover for Isoflavones by HPLC                            ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100094-ARS




                                                                                                                                            Example Reports
Red Clover for Isoflavones by HPLC                            ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100094-ATR
Red Clover Identity By TLC                                   ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100081-ARS
Red Clover Identity By TLC                                   ATR    $300.00      $240.00        $210.00       $180.00   CDA-00100081-ATR
Red Yeast Rice for Lovastatin (Statins) by HPLC              ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100202-ARS
Red Yeast Rice for Lovastatin (Statins) by HPLC              ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100202-ATR
Reishi Mushroom by HPLC                                      ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100230-ARS
Residual Solvent Testing by GC                               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00018006-ARS
Residual Solvent Testing by GC                               ATR    $300.00      $240.00        $210.00       $180.00   CDA-00018006-ATR
Residue on Ignition                                          ARS    $75.00       $60.00         $52.50        $45.00    CDA-00100066-ARS
Resveratrol by HPLC                                          ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100102-ARS
Resveratrol by HPLC                                          ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100102-ATR
Rhodiola Rosea (Goldenroot) Analysis by HPLC                 ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100059-ARS




                                                                                                                                            Micro-Bio
Rhodiola Rosea (Goldenroot) Analysis by HPLC                 ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100059-ATR
Rhubarb Identity Testing by Microscopy                       ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100029-ARS
Rhubarb Identity Testing by TLC                              ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100014-ARS
Rhubarb Identity Testing by TLC                              ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100014-ATR
Rose Hips Identity Testing by TLC                            ARS    $200.00      $160.00        $140.00       $120.00   CDA-00100015-ARS
Rose Hips Identity Testing by TLC                            ATR    $300.00      $240.00        $210.00       $180.00   CDA-00100015-ATR
Rosemary for Rosmarinic Acid By HPLC                         ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100082-ARS
Royal Jelly for 10-HDA by HPLC                               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00018005-ARS
Royal Jelly for 10-HDA by HPLC                               ATR    $350.00      $280.00        $245.00       $210.00   CDA-00018005-ATR




                                                                                                                                           Service List
Rutin Analysis by HPLC                                       ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100019-ARS
Rutin Analysis by HPLC                                       ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100019-ATR
Sample Preparation Fee (Special Requirements)                ARS    $150.00      $120.00        $105.00       $90.00    CDA-00100226-ARS
Sanguinaria (Blood Root) By HPLC                             ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100148-ARS
Sanguinaria (Blood Root) By HPLC                             ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100148-ATR
Saponins by Gravimetric Method                               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100286-ARS
Sarsaparilla Identity Testing by TLC                         ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100056-ARS
Sarsaparilla Identity Testing by TLC                         ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100056-ATR
Saw Palmetto Fatty Acid profile                               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100182-ARS
Schisandra Analysis for Schisandrins by HPLC                 ARS    $250.00      $200.00        $175.00       $150.00   CDA-00018502-ARS
Schisandra Analysis for Schisandrins by HPLC                 ATR    $350.00      $280.00        $245.00       $210.00   CDA-00018502-ATR
                                                                                                                                            Forms




Sclareolide by GC                                            ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100259-ARS
Serine by HPLC                                               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100358-ARS


      Tel. (949) 419-0288              Fax. (949) 419-0294         email. sales@chromadex.com             www.chromadex.com
                  38
Introduction
                                                                                                            Cost per Sample($)
                  SERVICE DESCRIPTION                                        Report 1 Sample 2-4     5-9     10+                          Service Code
                                                                             Type            Samples Samples
                  Serine by HPLC                                             ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100358-ATR
                  Sesamin by GC/HPLC                                         ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100168-ARS
                  Sesamin by GC/HPLC                                         ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100168-ATR
                  Sitosterol (Beta) by GC/MS                                 ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100057-ARS
                  Sitosterol (Beta) by GC/MS                                 ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100057-ATR
                  Sitosterol (Beta) by HPLC                                  ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100163-ATR
Validation




                  Skullcap by HPLC                                           ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100209-ARS
                  Skullcap for Flavonoids by HPLC                            ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100349-ARS
                  Skullcap for Flavonoids by HPLC                            ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100349-ATR
                  Solanesol by HPLC                                          ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100090-ARS
                  Solanesol by HPLC                                          ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100090-ATR
                  Solvent Analysis by LC-MS                                  ATR         $250.00         $200.00      $175.00   $150.00   CDA-00100153-ATR
                  Soy Analysis for Isoflavones by HPLC                        ARS         $250.00         $200.00      $175.00   $150.00   CDA-00018506-ARS
                  Soy Analysis for Isoflavones by HPLC                        ATR         $350.00         $280.00      $245.00   $210.00   CDA-00018506-ARS
Example Reports




                  Specific Gravity of Sample                                  ARS         $75.00          $60.00       $52.50    $45.00    CDA-00100114-ARS
                  Spirulina Identity for GLA by GC                           ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100169-ARS
                  Spirulina Identity Test by Microscopy                      ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100028-ARS
                  Spirulina Identity Test by TLC                             ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100002-ARS
                  Squalene by GC                                             ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100103-ATR
                  St. John’s Wort for Flavonoids by HPLC                     ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100204-ATR
                  St. John’s Wort for Hyperforin by HPLC                     ARS         $250.00         $200.00      $175.00   $150.00   CDA-00018507-ARS
                  St. John’s Wort for Hyperforin by HPLC                     ATR         $350.00         $280.00      $245.00   $210.00   CDA-00018507-ATR
                  St. John’s Wort for Hypericins by HPLC                     ARS         $250.00         $200.00      $175.00   $150.00   CDA-00018505-ARS
                  St. John’s Wort for Hypericins by HPLC                     ATR         $350.00         $280.00      $245.00   $210.00   CDA-00018505-ATR
                  Stevia for Stevioside and Reb A by HPLC                    ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100134-ARS
                  Stevia for Stevioside and Reb A by HPLC                    ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100134-ATR
Micro-Bio




                  Stevia Identity by TLC                                     ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100213-ARS
                  Sucralose by HPLC                                          ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100321-ARS
                  Sucralose by HPLC                                          ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100321-ATR
                  Sugars (Misc.) Analysis by GC                              ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100274-ARS
                  Sulfur Analysis                                            ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100258-ARS
                  Sulfur Dioxide (SO2) by Titration                          ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100261-ARS
                  Taurine by HPLC                                            ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100197-ARS
                  Taurine by HPLC                                            ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100197-ATR
Service List




                  Taxanes (Paclitaxel) by HPLC                               ARS         $250.00         $200.00      $175.00   $150.00   CDA-00019011-ARS
                  Taxanes (Paclitaxel) by HPLC                               ATR         $350.00         $280.00      $245.00   $210.00   CDA-00019011-ATR
                  TEA (Total Method) by HPLC                                 ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100231-ARS
                  TEA (Total Method) by HPLC                                 ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100231-ATR
                  Theanine, L- Analysis by HPLC                              ARS         $250.00         $200.00      $175.00   $150.00   CDA-00019008-ARS
                  Theanine, L- Analysis by HPLC                              ATR         $350.00         $280.00      $245.00   $210.00   CDA-00019008-ATR
                  Theobromine - Theophylline Analysis by HPLC                ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100330-ARS
                  Theobromine - Theophylline Analysis by HPLC                ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100330-ATR
                  Threonine by HPLC                                          ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100361-ARS
                  Threonine by HPLC                                          ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100361-ATR
                  Titration (Base Hydrolysis to Carboxylic Acid)             ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100065-ARS
                  TLC Fingerprint for Finished Products                      ATR         $300.00         $240.00      $210.00   $180.00   CDA-00100219-ATR
Forms




                  TLC Fingerprint with Bioluminex                            ARS         $350.00         $280.00      $245.00   $210.00   CDA-00100203-ARS
                  Tocopherol (Vitamin E) by HPLC                             ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100295-ARS


                                    Tel. (949) 419-0288            Fax. (949) 419-0294             email. sales@chromadex.com      www.chromadex.com
                                                                                                                                     39




                                                                                                                                           Introduction
                                                                                    Cost per Sample($)
SERVICE DESCRIPTION                                          Report 1 Sample 2-4     5-9     10+                        Service Code
                                                             Type            Samples Samples
Tocopherol Acetate (Vitamin E Acetate) by HPLC               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100195-ARS
Tocopherol Succinate (Vitamin E Succinate) by HPLC           ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100184-ARS
Tocopherols (Vitamin E) by HPLC                              ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100238-ARS
Tocotrienols by HPLC                                         ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100239-ARS
Tocotrienols by HPLC                                         ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100239-ATR
Total Dissolved Solids (TDS)                                 ARS    $50.00       $40.00         $35.00        $30.00    CDA-00100277-ARS
Tribulus or Fenugreek for Protodioscin by HPLC/UV            ARS    $250.00      $200.00        $175.00       $150.00   CDA-00019004-ARS




                                                                                                                                           Validation
Tribulus or Fenugreek for Protodioscin by HPLC/UV            ATR    $350.00      $280.00        $245.00       $210.00   CDA-00019004-ATR
Tryptophan/5-HTP (Griffonia) Testing for Peak X              ARS    $500.00      $400.00        $350.00       $300.00   CDA-00100030-ARS
Tryptophan/5-HTP (Griffonia) Testing for Peak X              ATR    $600.00      $480.00        $420.00       $360.00   CDA-00100030-ATR
Turmeric for Curcuminoids by HPLC                            ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100092-ARS
Turmeric for Curcuminoids by HPLC                            ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100092-ATR
Tyramine HCL by HPLC                                         ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100154-ARS
Tyrosine by HPLC                                             ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100362-ARS




                                                                                                                                            Example Reports
Tyrosine by HPLC                                             ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100362-ATR
UV/Vis Spectrophotometric Fingerprint                        ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100166-ARS
Valerian for Valerenic acids by HPLC                         ARS    $250.00      $200.00        $175.00       $150.00   CDA-00021001-ARS
Valerian for Valerenic acids by HPLC                         ATR    $350.00      $280.00        $245.00       $210.00   CDA-00021001-ATR
Valerian Root Identity by TLC                                ATR    $300.00      $240.00        $210.00       $180.00   CDA-00100117-ATR
Valine by HPLC                                               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100363-ARS
Valine by HPLC                                               ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100363-ATR
Vanadyl Sulfate for Vanadium by ICP                          ARS    $250.00      $200.00        $175.00       $150.00   CDA-00021010-ARS
Vanilla for Vanillins by HPLC                                ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100246-ARS
Vanilla for Vanillins by HPLC                                ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100246-ATR
Vitamin A (Acetate) by HPLC                                  ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100270-ARS
Vitamin A (Acetate) by HPLC                                  ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100270-ATR




                                                                                                                                            Micro-Bio
Vitamin A (Palmitate) by HPLC                                ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100335-ARS
Vitamin A (Palmitate) by HPLC                                ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100335-ATR
Vitamin A (Retinol) by HPLC                                  ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100269-ARS
Vitamin A (Retinol) by HPLC                                  ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100269-ATR
Vitamin B Panel by HPLC                                      ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100265-ARS
Vitamin B Panel by HPLC                                      ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100265-ATR
Vitamin B1 (Thiamine) by HPLC                                ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100260-ARS
Vitamin B1 (Thiamine) by HPLC                                ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100260-ATR
Vitamin B12 (Cyanocobalamin) by HPLC                         ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100185-ARS




                                                                                                                                           Service List
Vitamin B12 (Cyanocobalamin) by HPLC                         ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100185-ATR
Vitamin B2 (Riboflavin) by HPLC                               ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100373-ARS
Vitamin B2 (Riboflavin) by HPLC                               ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100373-ATR
Vitamin B3 (Niacinamide) by HPLC                             ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100322-ARS
Vitamin B3 (Niacinamide) by HPLC                             ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100322-ATR
Vitamin B5 (D-Calcium Phosphate) by HPLC                     ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100374-ARS
Vitamin B5 (D-Calcium Phosphate) by HPLC                     ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100374-ATR
Vitamin B6 (Pyroxidine) by HPLC                              ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100375-ARS
Vitamin B6 (Pyroxidine) by HPLC                              ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100375-ATR
Vitamin C (Ascorbic Acid) by HPLC                            ARS    $250.00      $200.00        $175.00       $150.00   CDA-00021009-ARS
Vitamin C (Ascorbic Acid) by HPLC                            ATR    $350.00      $280.00        $245.00       $210.00   CDA-00021009-ATR
                                                                                                                                            Forms




Vitamin D2 (Ergocalciferol - formula) by HPLC                ARS    $250.00      $200.00        $175.00       $150.00   CDA-00100377-ARS
Vitamin D2 (Ergocalciferol - formula) by HPLC                ATR    $350.00      $280.00        $245.00       $210.00   CDA-00100377-ATR


      Tel. (949) 419-0288              Fax. (949) 419-0294         email. sales@chromadex.com             www.chromadex.com
                  40
Introduction
                                                                                                            Cost per Sample($)
                  SERVICE DESCRIPTION                                        Report 1 Sample 2-4     5-9     10+                          Service Code
                                                                             Type            Samples Samples
                  Vitamin D2 (Ergocalciferol - raw) by HPLC                  ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100376-ARS
                  Vitamin D2 (Ergocalciferol - raw) by HPLC                  ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100376-ATR
                  Vitamin D3 (Cholecalciferol - formula) by HPLC             ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100378-ARS
                  Vitamin D3 (Cholecalciferol - formula) by HPLC             ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100378-ATR
                  Vitamin D3 (Cholecalciferol - raw) by HPLC                 ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100268-ARS
                  Vitamin D3 (Cholecalciferol - raw) by HPLC                 ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100268-ATR
Validation




                  Vitamin E (Acetate) by HPLC                                ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100380-ARS
                  Vitamin E (Acetate) by HPLC                                ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100380-ATR
                  Vitamin E (Succinate) by HPLC                              ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100381-ARS
                  Vitamin E (Succinate) by HPLC                              ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100381-ATR
                  Vitamin E (Tocopherol) by HPLC                             ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100379-ARS
                  Vitamin E (Tocopherol) by HPLC                             ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100379-ATR
                  Vitamin K1 (Menadione - formula) by HPLC                   ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100384-ARS
                  Vitamin K1 (Menadione - formula) by HPLC                   ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100384-ATR
Example Reports




                  Vitamin K1 (Menadione - raw) by HPLC                       ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100383-ARS
                  Vitamin K1 (Menadione - raw) by HPLC                       ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100383-ATR
                  Vitamin K1 (Phylloquinone - raw) by HPLC                   ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100188-ARS
                  Vitamin K1 (Phylloquinone - raw) by HPLC                   ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100188-ATR
                  Vitamin K1 (Phylloquinones- formula) by HPLC               ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100382-ARS
                  Vitamin K1 (Phylloquinones- formula) by HPLC               ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100382-ATR
                  Vitamin K2 (Menaquinone-4) by HPLC                         ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100346-ARS
                  Vitamin K2 (Menaquinone-4) by HPLC                         ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100346-ATR
                  Vitamin K2 (Menaquinone-7) by HPLC                         ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100118-ARS
                  Vitamin K2 (Menaquinone-7) by HPLC                         ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100118-ATR
                  Vitex Agnus Castus (Chaste Tree) by HPLC                   ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100100-ARS
                  Vitex Agnus Castus (Chaste Tree) by HPLC                   ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100100-ATR
Micro-Bio




                  Vitex Agnus Castus Identity by TLC                         ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100171-ARS
                  Wasabi for Glucosinolate by HPLC                           ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100180-ATR
                  Water Content by Karl Fischer                              ARS         $95.00          $76.00       $66.50    $57.00    CDA-00100207-ARS
                  Water Content by Loss on Drying                            ARS         $90.00          $72.00       $63.00    $54.00    CDA-00100130-ARS
                  White Willow Bark for Salicin by HPLC                      ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100174-ARS
                  White Willow Bark for Salicin by HPLC                      ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100174-ATR
                  Wild Yam Identity by TLC                                   ARS         $200.00         $160.00      $140.00   $120.00   CDA-00100080-ARS
                  Yohimbine by HPLC                                          ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100161-ARS
Service List




                  Yohimbine by HPLC                                          ATR         $350.00         $280.00      $245.00   $210.00   CDA-00100161-ATR
                  Yucca Identity by TLC                                      ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100142-ARS
                  Zinc by ICP                                                ARS         $250.00         $200.00      $175.00   $150.00   CDA-00100337-ARS
Forms




                                  Tel. (949) 419-0288              Fax. (949) 419-0294             email. sales@chromadex.com      www.chromadex.com
                                                                                                                                            41




                                                                                                                                                  Introduction
Amino Acids                                                                                 Cost per Sample($)
 SERVICE DESCRIPTION                                        Report 1 Sample 2-4     5-9     10+                                Service Code
                                                            Type            Samples Samples
 Alanine                                                    ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100364-ARS
 Arginine                                                   ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100152-ARS
 9-Aminobutyric Acid                                        ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100365-ARS
 Asparagine                                                 ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100367-ARS
 Aspartic Acid                                              ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100350-ARS
 Cystine                                                    ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100351-ARS




                                                                                                                                                  Validation
 Glutamic Acid                                              ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100352-ARS
 Glutamine                                                  ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100369-ARS
 Glycine                                                    ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100151-ARS
 Histidine                                                  ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100353-ARS
 4-Hydroxyisoleucine                                        ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100044-ARS
 Hydroxyproline                                             ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100368-ARS
 Isoleucine                                                 ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100354-ARS




                                                                                                                                                   Example Reports
 Leucine                                                    ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100208-ARS
 Lysine                                                     ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100355-ARS
 Methionine                                                 ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100356-ARS
 Norvaline                                                  ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100366-ARS
 Ornithine                                                  ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100370-ARS
 Phenylalanine                                              ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100181-ARS
 Proline                                                    ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100357-ARS
 Serine                                                     ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100358-ARS
 Taurine                                                    ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100197-ARS
 Theanine                                                   ARS         $250.00         $200.00        $175.00       $150.00   CDA-00019008-ARS
 Threonine                                                  ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100361-ARS




                                                                                                                                                   Micro-Bio
 Tryptophan                                                 ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100030-ARS
 Tyrosine                                                   ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100362-ARS
 Valine                                                     ARS         $250.00         $200.00        $175.00       $150.00   CDA-00100363-ARS




Multiple Amino Acid Panels: Please note that ChromaDex can test for multiple amino acids in a single
assay, but not all amino acids can be tested in a single assay. Multiple amino acid samples will need to




                                                                                                                                                  Service List
be quoted based on the amino acids being screened as well as the composition of the sample matrix.


                                                                                                                                                   Forms




          Tel. (949) 419-0288         Fax. (949) 419-0294              email. sales@chromadex.com                www.chromadex.com
                  42
Introduction

                  Vitamins                                                                                  Cost per Sample($)
                  SERVICE DESCRIPTION                                        Report 1 Sample 2-4     5-9     10+                              Service Code
                                                                             Type            Samples Samples
                  Beta-carotene                                              ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100371-ARS
                  Biotin - raw                                               ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100076-ARS
                  Biotin – formula (w/ sample clean up)                      ARS        $300.00         $240.00           $210.00   $180.00   CDA-00100372-ARS
                  Folic Acid - raw                                           ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100398-ARS
                  Folic Acid – formula (w/ sample clean up)                  ARS        $300.00         $240.00           $210.00   $180.00   CDA-00100267-ARS
Validation




                  Vitamin A (Retinol)                                        ARS        $250.00         $200.00           $175.00   $150.00   CDA-001002679-ARS
                  Vitamin A (Acetate)                                        ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100270-ARS
                  Vitamin A (Palmitate)                                      ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100335-ARS
                  Vitamin B1 (Thiamine)                                      ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100260-ARS
                  Vitamin B2 (Riboflavin)                                     ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100373-ARS
                  Vitamin B3 (Niacin/Niacinamide)                            ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100322-ARS
                  Vitamin B5 (D-Calcium Pantothenate)                        ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100374-ARS
Example Reports




                  Vitamin B6 (Pyridoxine)                                    ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100375-ARS
                  Vitamin B12 (Cyanocobalamin)                               ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100185-ARS
                  Vitamin C (Ascorbic Acid)                                  ARS        $250.00         $200.00           $175.00   $150.00   CDA-00021009-ARS
                  Vitamin D2 (Ergocalciferol – raw)                          ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100376-ARS
                  Vitamin D2 (Ergocalciferol – formula) (w/ sample clean     ARS        $300.00         $240.00           $210.00   $180.00   CDA-00100377-ARS
                  up)
                  Vitamin D3 (Cholecalciferol – raw)                         ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100268-ARS
                  Vitamin D3 (Cholecalciferol – formula) (w/ sample clean    ARS        $300.00         $240.00           $210.00   $180.00   CDA-00100378-ARS
                  up)
                  Vitamin E (Tocopherol)                                     ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100379-ARS
                  Vitamin E (Acetate)                                        ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100380-ARS
Micro-Bio




                  Vitamin E (Succinate)                                      ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100381-ARS
                  Vitamin K1 (Phylloquinones – raw)                          ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100188-ARS
                  Vitamin K1 (Phylloquinones – formula) (w/ sample           ARS        $300.00         $240.00           $210.00   $180.00   CDA-00100382-ARS
                  clean up)
                  Vitamin K2 (Menaquinones)                                  ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100346-ARS
                  Vitamin K3 (Menadione – raw)                               ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100383-ARS
                  Vitamin K3 (Menadione – formula) (w/ sample clean up) ARS             $300.00         $240.00           $210.00   $180.00   CDA-00100384-ARS
                  Tocotrienols                                               ARS        $250.00         $200.00           $175.00   $150.00   CDA-00100239-ARS
Service List




                  Multiple Vitamin Panels: Please note that ChromaDex can test for multiple Vitamins in a single assay,
                  but not all Vitamins can be tested in a single assay. Multiple Vitamin samples will need to be quoted
                  based on the vitamins being screened as well as the composition of the sample matrix.


                                 GENERAL SERVICES INFORMATION
                                 Turn Around Times
                                                      # Days             Surcharge
                                 Standard             10 days            None
                                 Rush                 5 days             2.0X
                                 Expedite             3 days             2.5X
Forms




                                 Report Types:
                                 Analytical Results Sheet       ARS      One page standard results sheet, reported values only.
                                 Analytical Test Report         ATR      Multi-page analytical report with all method detials

                                     Tel. (949) 419-0288          Fax. (949) 419-0294             email. sales@chromadex.com           www.chromadex.com
                                                                                                             43




                                                                                                                  Introduction
                                                                                                                  Validation
ChromaDex™ Literature Search Services
    Are you starting research and development on a
                     new botanical?




                                                                                                                   Example Reports
   Are you looking to substantiate your label claims for a formulation or a
                            specific ingredient?
 Backing up your R&D efforts and substantiating your claims will take a
 significant literature search effort.
 Let ChromaDex™ perform literature searches for you. ChromaDex™ currently subscribes to
 some of the best literature search services available and can support your R&D efforts which will
 help substantiate your product claims.
 ChromaDex™ can provide literature search reports including abstracts for:




                                                                                                                   Micro-Bio
        1.        Botanicals by scientific and common names
        2.        Botanicals by related phytochemicals
        3.        Botanicals by specific type of biological activity
        4.        Botanicals for analytical methods
        5.        Botanicals by any specific key word search

 Once the search has been completed ChromaDex™ will filter and sort the data and provide a
 report with abstracts for the articles which seem pertinent to desired search criteria.


                                                                                                                  Service List
 Literature Search Service Fee Schedule
 Description of the Service                                                Cost Estimate($)
 Basic Keyword Literature Search with Abstract report                      $1000
                                                                                                                  Ser

 ChromaDex™ to provide publications as PDF files                            $25 to $100 per publication
                                                                                             blica
                                                                                               icat
                                                                                               icati
                                                                                            ublic on
                                                                                                                  S


 Creation of a Botanical “monograph” based on search                       $2500 to $5000
                                                                           $    0      00
                                                                                      0000

 For examples of ChromaDex™ literature search reports or for examples of ChromaDex™
 created monographs please contact our technical sales department at 949-419-0288 or e-mail
                                                                                                                   Forms




 us at sales@chromadex.com


      Tel. (949) 419-0288       Fax. (949) 419-0294                    hromade
                                                                        romadex
                                                                         omade
                                                         email. sales@chromadex.com      www.chromadex.com
                  44 PRICE LIST OF BIOASSAYS
Introduction
                      A. BIOCHEMICAL ASSAYS
                  Code               Bioassay                                                 Pharmacological Relevance                                Price
                  CDA-BCA01-ATR      Alpha - Amylase Inhibition Assay                         Obesity, Diabetes                                        $395.00
                  CDA-BCA02-ATR      Alpha - Glucosidase Inhibition Assay                     Anti-diabetic                                            $395.00
                  CDA-BCA03-ATR      Beta - Glucuronidase Inhibition Assay                    Anti-oxidant                                             $495.00
                  CDA-BCA04-ATR      ABTS Radical Scavenging Assay                            Anti-oxidant                                             $495.00
                  CDA-BCA05-ATR      Acetylcholinesterase Inhibition Assay                    Cognition enhancement                                    $395.00
                  CDA-BCA06-ATR      Aryl Sulphatase Inhibition Assay                         Axillary odor                                            $995.00
                  CDA-BCA07-ATR      Butyrylcholinesterase Inhibition Assay                   Cognition enhancement                                    $395.00
Validation




                  CDA-BCA08-ATR      Collagenase Inhibition Assay                             Anti-ageing / Anti-wrinkle                              $1,875.00
                  CDA-BCA09-ATR      Nitric-oxide Scavenging Assay                            Anti-oxidant, Alzheimer’s disease                        $550.00
                  CDA-BCA10-ATR      Superoxide Anion Scavenging Activity (PMS-NADH system)   Anti-oxidant                                             $660.00
                  CDA-BCA11-ATR      DPP IV Inhibition Assay                                  Anti-diabetic, obesity                                  $1,150.00
                  CDA-BCA12-ATR      DPPH Assay                                               Anti-oxidant                                             $950.00
                  CDA-BCA13-ATR      Elastase Inhibition Assay                                Anti-wrinkle, Anti-ageing                               $1,150.00
                  CDA-BCA14-ATR      Hyaluronidase Inhibition Assay                           Anti-inflammatory, Ant- wrinkle                          $1,250.00
                  CDA-BCA15-ATR      Hydroxyl Radical Scavenging Assay                        Anti-oxidant                                             $825.00
Example Reports




                  CDA-BCA16-ATR      Lipase Inhibition Assay                                  Obesity                                                  $395.00
                  CDA-BCA17-ATR      15 - Lipoxygenase Inhibition Assay                       Anti-inflammatory                                         $995.00

                  CDA-BCA18-ATR      Trypsin Inhibition Assay                                 Anti-inflammatory                                         $825.00
                  CDA-BCA19-ATR      Xanthine Oxidase Inhibition Assay                        Gout                                                     $495.00
                  CDA-BCA20-ATR      TC- PTPase Inhibition Assay                              TC-PTPase inhibitors are likely to inhibit PTP-1B)      $1,550.00
                  CDA-BCA21-ATR      PTP-IB Inhibition Assay                                  Anti-diabetic, Anti-obesity                             $2,195.00
                  CDA-BCA22-ATR      Aldolase Inhibition Assay                                Obesity                                                  $395.00
                  CDA-BCA23-ATR      COX-I Inhibition Assay                                   Done along COX II assay to know selectivity             $1,395.00
                  CDA-BCA24-ATR      COX II Inhibition Assay                                  Inflammation                                             $1,550.00
                  CDA-BCA25-ATR      Phosphodiesterase-1 Inhibition Assay                     Arthritis                                                $795.00
Micro-Bio




                  CDA-BCA26-ATR      Protein Phosphatase-1 Inhibition Assay                   Cognition enhancement                                   $1,550.00
                  CDA-BCA27-ATR      Trolox Equivalent Antioxidant Capacity Assay             Anti-oxidant                                            $1,150.00
                  CDA-BCA28-ATR      Thymidine phosphorylase (TP) Inhibition Assay            Anti-psoriasis                                           $395.00
                  CDA-BCA29-ATR      RHO-Kinase (ROCK-II) new                                 Erectile dysfunction/Male impotency                     $2,500.00
                  CDA-BCA30-ATR      Caspase-3 inhibition Assay new                           Alzheimer’s, neurodegenerative                           $795.00
                  CDA-BCA31-ATR      Angiotensin converting enzyme (ACE) Inhibition new       Hypertension                                            $1,875.00
                  CDA-BCA32-ATR      Tyrosinase Inhibition new                                Skin whitening                                           $500.00

                  CDA-BCA33-ATR      PARP Inhibition new                                      Neuro degenerative disorders                            $3,500.00
Service List




                  CDA-BCA34-ATR      PLA2 Inhibition new                                      Anti-inflammatory                                         $295.00
                  CDA-BCA35-ATR      PAF acetylhydrolase Inhibition new                       Atherosclerosis                                         $1,495.00
                  CDA-BCA36-ATR      IKK-Beta(NF-B kinase) Inhibition new                     Anti-Diabetic                                           $2,500.00
                  CDA-BCA37-ATR      Glucose-6-phosphatase new                                Anti-Diabetic                                           $1,495.00
                  CDA-BCA38-ATR      P70S6 Kinase Inhibition                                  Anti-Diabetic                                           $1,495.00

                      B. Cell Based Assays
                  Code               Bioassay                                                 Pharmacological Relevance                                Price
                                     Lymphocyte Proliferation Assays
                  CDA-CA01A-ATR      a. Naïve and LPS treated lymphocytes                     Immune modulation                                        $1,375.00
                  CDA-CA01B-ATR      b. Naïve and PHA-L treated lymphocytes                   Immune modulation                                        $1,375.00
                  CDA-CA01C-ATR      c. Naïve and Con A treated lymphocytes                   Immune modulation                                        $1,375.00
Forms




                  CDA-CA02-ATR       NO Release (in J774A.1 macrophages)                      Immune stimulation                                       $1,625.00
                  CDA-CA03-ATR       NO Scavenging (in LPS prestimulated macrophges)          Anti-oxidant                                             $1,625.00
                  CDA-CA04-ATR       Macrophage Phagocytosis                                  Immune modulation                                        $1,385.00

                                  Tel. (949) 419-0288                Fax. (949) 419-0294      email. sales@chromadex.com                     www.chromadex.com
                                                                                                                                                          45




                                                                                                                                                               Introduction
B. Cell Based Assays (Continued)
Code                 Bioassay                                                       Pharmacological Relevance                                   Price
CDA-CA05-ATR         LTB4 Release Assay                                             Anti-inflammatory                                            $1,995.00
CDA-CA06-ATR         Hepatoprotection Assay using t-BH                              Hepatoprotection                                            $950.00
CDA-CA07-ATR         Elastin Release Assay                                          Anti-wrinkle                                                $1,875.00
CDA-CA08-ATR         Histamine Release Assay                                        Anti-inflammatory, Anti-allergy                              $2,950.00
CDA-CA09-ATR         Chromosomal Aberration Human Lymphocytes                       Safety assessment                                              Call
CDA-CA10-ATR         Micronucleus Assay using human Lymphocytes                     Safety assessment                                              Call
CDA-CA11-ATR         Melanin Release using B-16                                     Skin tanning/lightening                                        Call
CDA-CA12-ATR         PGE2 Release J774A.1 Macrophage Cells                          Anti-inflammatory                                               Call




                                                                                                                                                               Validation
CDA-CA13-ATR         Insulin Release                                                Anti-diabetic                                                  Call
CDA-CA14-ATR         Collagen release NIH-3T3                                       Anti-wrinkle                                                   Call

C. Miscellaneous Bioassays




                                                                                                                                                                 li
Code                 Bioassay                                                       Pharmacological Relevance                                    Price
CDA-MA01-ATR         Brine Shrimp Lethality Test                                    Non specific general bioassay                                 $99.00
CDA-MA02-ATR         Anti-Staphylococcus aureus (MTCC 737)                          Antibacterial activity                                       $250.00
CDA-MA03-ATR         Anti-Escherichia coli (MTCC 1687)                              Antibacterial activity                                       $250.00




                                                                                                                                                                              s
                                                                                                                                                                Example Reports
CDA-MA04-ATR         Anti-Kleibsiella pnemoniae (MTCC 109)                          Antibacterial activity                                       $250.00
CDA-MA05-ATR         Anti-Pseudomonas aeruginosa (MTCC 1688)                        Antibacterial activity                                       $250.00
CDA-MA06-ATR         Anti-Proteus vulgaris (MTCC 1771)                              Antibacterial activity                                       $250.00
CDA-MA07-ATR         Anti-Staphylococcus epidermidis (MTCC 435)                     Antibacterial activity                                       $250.00
CDA-MA08-ATR         Anti-Propionibacterium acne (MTCC 1951)                        Antibacterial activity                                       $250.00
CDA-MA09-ATR         Anti-S.mutans (MTCC 890)                                       Antibacterial activity                                       $300.00
CDA-MA10-ATR         Anti-S.salivarius (ATCC 13419-derived)                         Antibacterial activity                                       $300.00
CDA-MA11-ATR         Anti-S.sanguis (ATCC 10556-derived)                            Antibacterial activity                                       $300.00
CDA-MA12-ATR         Anti-Candida albicans (MTCC 183)                               Antifungal activity                                          $250.00
CDA-MA13-ATR         Anti-Trichophyton rubrum (MTCC 296)                            Antifungal activity                                          $325.00
CDA-MA14-ATR         Anti-Microsporum gypseum (MTCC 2819)                           Antifungal activity                                          $325.00




                                                                                                                                                                Micro-Bio
CDA-MA15-ATR         Caenorhabditis elegans Lethality                               Antihelmintic                                                  Call

D. New Cell Based Assays
Code                Bioassay                                                        Pharmacological Relevance                                   Price
CDA-SPA01-ATR       MTS Cell Proliferation Assay                                    Cancer, Toxicity                                            $250.00
CDA-SPA02-ATR       Methylene Blue - Cytotoxicity Assay                             Cancer, Toxicity                                            $250.00
CDA-SPA03-ATR       Apoptosis - DNA Fragmentation                                   Cancer, Inflammation                                         $700.00
CDA-SPA04-ATR       Apoptsis - Caspase 3/7                                          Cancer, Inflammation                                         $700.00
CDA-SPA05-ATR       Apoptsis - Caspase 8                                            Cancer, Inflammation                                         $700.00




                                                                                                                                                               Service List
CDA-SPA06-ATR       Apoptsis - Caspase 9                                            Cancer, Inflammation                                         $700.00
CDA-SPA07-ATR       Prostaglandin E2                                                Inflammation                                                 $700.00
CDA-SPA08-ATR       Ca++ Flux Assay for Endothelin Receptor                         Cardiovascular                                              $1,000.00
CDA-SPA09-ATR       Nuclear Factor kappa B                                          Inflammation                                                 $1,000.00
CDA-SPA10-ATR       Transcription Factor Nerf2, Activation of phase 2 enzymes       Oxidative Stress, Carcinogenesis                            $1,000.00
CDA-SPA11-ATR       Mechanism - based assays for Pseudomonas (Quorum sens-          Antimicrobial                                               $250.00
                    ing)
CDA-SPA12-ATR       ORAC and DPPH                                                   Antioxidant                                                 $250.00

      Notes:
      1.   Turn around times will vary depending on the assay, but most bioassay services should be approximately to 6 weeks.
      2.   The prices above are based on a “per sample” basis. There will be volume discounts for: 2-4 Samples, 5-9 Samples, 10+ Samples
                                                                                                                                                                Forms




      3.   The prices quoted above are based on 10 data points per sample or FIVE sample concentrations in duplicate.
      4.   If you would like a custom quote based on a large number of samples and a custom request for data point format please call.
      5.   Minimum sample requirement is 1g, assuming the material is water soluble. If the compound is not water soluble we may require up to 25g of
           the material.

 Tel. (949) 419-0288               Fax. (949) 419-0294               email. sales@chromadex.com                    www.chromadex.com
                                                                                                                                                                                                                                                                           46
                                                                                                                                                  SAMPLE SUBMISSION FORM
                                                                                                                           Payment Address (accounting):
                                                                                                                                                                                                Sample Submission Location
        Company:
                                                                                                                                                                                    ChromaDex Analytics                             Chromadex, Inc.
        Contact Name (for reports):                                                                                                   ChromaDex, Inc.                               Attn: Sample Management                         Attn: Sample Management
                                                                                                                                      Accounts Receivable                           2830 Wilderness Place                           13161 56th Court N Suite 201
        Address (for reports):
                                                                                                                                                                                    Boulder, CO 80301 USA                           Clearwater, FL 33760 USA
                                                                                                                                      2952 S. Daimler st.
                                                                                                                                      Santa Ana, CA 92705                        BEFORE FILLING OUT THIS FORM PLEASE READ BELOW:
         Address (for invoice):                                                                                                                                                    1. Please contact a ChromaDex Representative at 949-419-0288 before
                                                                                                                                      Tel: 949.419.0288                               shipping samples.
                                                                                                                                      Fax: 949.419.0294                            2. Please fax a copy of this form to 949-419-0294 before shipping samples.




Tel. (949) 419-0288
         Contact Phone#:                                             Contact Fax#:                                                                                                 3. Please Ship the samples to the specified location checked above.
                                                                                                                                                                                   4. If the number of samples exceeds six please attach a separate sheet with
         Contact e-mail (for reports):                                                                                                                                                the Sample Information. (Sample names and Sample Lot #s)
SAMPLE INFORMATION

                Sample Name:                                                                                                                      Lot #:
                # of Samples:           Storage Conditions:                                                 Sample Amount:                                                       Note: Each sample should be clearly identified with a name and lot/ID number.

ASSAY INFORMATION
                Assay                        Assay                                       Spec                       Method #                   *Report Type           **Turn Around Time          ChromaDex Part #         NOTES:     (FOR CHROMADEX USE ONLY)




Fax. (949) 419-0294
                  #                                                                                                 (if known)                Please circle one         Please circle one


                             1                                                                                                                    ARS      ATR        10     5      3   Other



                             2                                                                                                                    ARS      ATR        10     5      3   Other



                             3                                                                                                                    ARS      ATR        10     5      3   Other




                             4                                                                                                                    ARS      ATR        10     5      3   Other



                             5                                                                                                                    ARS      ATR        10     5      3   Other




email. sales@chromadex.com
                             6                                                                                                                    ARS      ATR        10     5      3   Other



*REPORT INFORMATION                                                                                                                                                        Credit Card Details (if paying by credit card):
         ANALYTICAL RESULT SHEET(ARS): One page sum-                       ANALYTICAL TEST REPORT(ATR): This is a full report, including methods                               AMEX      VISA        MC      Exp. Date: _____________________
         mary report, results only                                         data details and chromatograms.
      *For more information about these report types and their associated fees please call 949-419-0288. If report is not indicated, an ARS will be assigned
                                                                                                                                                                           Card #: ____________________________________________________
**TURNAROUND TIME
            Standard:10 Working Days Priority Service: 5 Working Days (list price X2)                  Priority Service: 3 Working Days (list price X2.5)
       Note: The start time will begin once the sample and work order has been received by the testing facility. If nothing is marked, 10 working days will be assigned.
                                                                                                                                                                           Name on Card: _____________________________________________
CLIENT AUTHORIZATION                                                                                                                                                                             Terms: Due upon delivery of completed results, with an approved




www.chromadex.com
                                                                                                                                                                                                 ChromaDex credit account. All work is subject to our Standard Terms and
          Date:                                  Signature:                                                                                                                                      Conditions for the Purchase and Sale of ChromaDex Products and/or Ser-
                                                                                                                                                                                                 vices, a copy of which has been provided to Company and is incorporated
          Purchase Order #:                                                       Full Name:                                                                                                     herein by this reference.
                                                                                                                                                                                                 Note: Please sign to confirm services, pricing and terms noted above, as
              Work Order # (to be assigned):                                                               Accepted:                                                                             an authorized Representative of the company reference above.
                                             STANDARD TERMS AND CONDITIONS FOR THE PURCHASE AND SALE OF CHROMADEX, INC PRODUCTS AND/OR SERVICES                                                                                47
1. Definitions. As used in these Terms and Conditions (“Agreement”), (a) “Seller” means ChromaDex, Inc., its             (G) BUYER WARRANTS AND REPRESENTS TO SELLER THAT ALL SAMPLES TO BE SENT TO
affiliates and their respective successors and assigns, (b) “Buyer” means the party executing this Agreement to          SELLER FOR ANALYSIS SHALL BE IN A SAFE AND STABLE CONDITION AND BUYER SHALL
purchase the Products or Services and/or the party accepting delivery of the Products or Services under this             INDEMNIFY, DEFEND AND HOLD SELLER HARMLESS FOR ANY AND ALL DAMAGES WHICH
Agreement, (c) “Products” mean, but are not limited to, the standards, kits reference materials and other                SELLER MAY SUFFER AS A RESULTS OF ANY SAMPLE NOT BEING IN A SAFE OR STABLE
equipment and goods provided by Seller under this Agreement, and (d) “Services” means all lab work and other             CONDITION, NOTWITHSTANDING THAT BUYER MAY HAVE GIVEN AN INDICATION ON THE
services provided by Seller in connection with the sale, use or installation of the Products.                            SAMPLE OR ANY ORDER FORM OF ANY PERCEIVED PROBLEM WITH THE SAMPLE.
2. Acceptance, Merger and Integration. Buyer will be deemed to have accepted this Agreement when Seller                  9. Sample Storage. Samples will be destroyed by Seller 30 days after the analysis has been completed by Seller.
returns to Buyer an executed copy of this Agreement, by confirming this Agreement by its purchase agreement or           If Buyer desires a sample to be retained by Seller, Buyer must so request in writing, in which case the terms on
confirmation, or by acceptance of delivery of the Products or Services under this Agreement. Seller will be              which the sample will be retained must be agreed in writing between Seller and Buyer. In the absence of such
deemed to have accepted this Agreement when Buyer returns to Seller an executed copy of this Agreement, or, at           mutual agreement, Seller shall have no obligation to retain the sample.
Seller’s option, when Seller begins substantial performance under this Agreement. Seller reserves the right to
accept or reject any purchase agreement or confirmation. Buyer has no right to cancel or defer shipment, delivery        10. LIMITATION OF LIABILITY. TO THE FULLEST EXTENT PERMITTED BY LAW, THE PARTIES
or installation unless agreed to in writing by Seller. Notwithstanding the manner in which Buyer accepts this            WAIVE AND RELINQUISH ANY CLAIMS, DEMANDS, AND CAUSES OF ACTION OR RECOVERIES
Agreement, Buyer’s acceptance of this Agreement is limited exclusively to the acceptance of all of Seller’s terms        FOR PUNITIVE DAMAGES, EXEMPLARY DAMAGES, OR STATUTORY DAMAGES. IN NO EVENT
and conditions set forth in this Agreement. Buyer may acknowledge this Agreement by its purchase agreement,              WILL SELLER BE LIABLE FOR INDIRECT, SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES
confirmation or acknowledgment form, but any and all terms and conditions contained in such purchase                     ARISING UNDER THIS AGREEMENT OR OTHERWISE WITH RESPECT TO THE SALE OF THE
agreement, confirmation or acknowledgment form or other communications with respect to the transaction                   PRODUCTS OR PROVISION OF SERVICES, INCLUDING ANY LOST REVENUES OR PROFITS,
contemplated by this Agreement, or subsequent to the date hereof, shall be without any force and effect. This            CONSEQUENTIAL AND/OR INCIDENTAL DAMAGES, BUSINESS INTERRUPTION OR DAMAGE TO
Agreement, and all exhibits, riders or limited warranties attached hereto, is intended to be the exclusive and final     BUSINESS REPUTATION, REGARDLESS OF THE THEORY UPON WHICH ANY CLAIM MAY BE
statement of the terms and understandings relative to the subject matter hereof, merging herein and superseding all      BASED, INCLUDING ANY TORT OR STATUTORY CAUSES OF ACTION. NOTWITHSTANDING THE
negotiations and prior written or oral agreements between the parties as to the subject matter of the purchase of        TERMS OF ANY LIMITED WARRANTY, AND/OR IN THE EVENT ANY LIMITED WARRANTY
the Products or Services.                                                                                                PROVIDED TO BUYER FAILS OF ITS ESSENTIAL PURPOSE, IN NO EVENT WILL SELLER’S ENTIRE
3. Payment. Payment shall be net thirty (30) days from the date of shipment; provided, however, Seller reserves          LIABILITY TO BUYER (IN TORT, CONTRACT, FOR INTELLECTUAL PROPERTY INFRINGEMENT, OR
the right to modify such credit terms in its sole and absolute discretion. Failure to make prompt and full payment       OTHERWISE) EXCEED THE PURCHASE PRICE ACTUALLY PAID BY BUYER FOR THE PRODUCTS
hereunder constitutes a material breach of this Agreement and affords Seller the right to suspend its performance        AND/OR SERVICES SUBJECT TO THE CONTRACT OR AGREEMENT IN DISPUTE, OR ANY
without liability to Buyer and cancel this Agreement and any purchase orders. Buyer has no right of setoff. If full      DEFECTIVE OR NONCONFORMING PORTION THEREOF, WHICHEVER IS THE LESSER AMOUNT.
payment is not made when due, Seller shall be entitled to interest on any amount unpaid at the rate of 1.5% per          BOTH PARTIES UNDERSTAND AND AGREE THAT THIS LIMITATION OF LIABILITY ALLOCATES
month until Seller receives payment in full. In addition, if any amount payable to Seller is not received by Seller      RISK OF NONCONFORMING GOODS BETWEEN THE PARTIES AS AUTHORIZED BY THE UNIFORM
within 10 days of the due date, a late payment processing charge equal to 6% of such delinquent amount will be           COMMERCIAL CODE AND OTHER APPLICABLE LAW. THE PRICE OF THE PRODUCTS AND
paid by Buyer to Seller to defray the expense incident to the processing, administration and collection of               SERVICES REFLECTS THIS ALLOCATION OF RISK AND THE LIMITATIONS OF LIABILITY,
delinquent payments. Buyer agrees to reimburse Seller for any and all expenses Seller may incur, including               INCLUDING THE EXCLUSION OF SPECIAL, INDIRECT, CONSEQUENTIAL AND INCIDENTAL
reasonable attorneys' fees, in taking any action contemplated by this Paragraph.                                         DAMAGES, IN THIS AGREEMENT.

4. Taxes and Import Duties. The price of the Products or Services specified does not include federal taxes, state        11. Default. The failure of Buyer to perform any obligation hereunder, the failure to materially perform any
or local sales taxes, use taxes, occupational taxes or import duties. Unless prohibited by law, Buyer is responsible     other agreements between Buyer and Seller, or Buyer’s bankruptcy, insolvency, fraud or inability to pay its debts
for and shall pay all applicable sales, use, occupational, excise, value added or other similar taxes or import duties   as they mature, shall constitute a default under this Agreement and shall, in addition to any other remedies at law
applicable to the manufacture, sale, price, delivery or use of the Products or Services provided by Seller, or in lieu   or in equity, afford Seller, among other remedies, all of the remedies of a secured party under the applicable
thereof, Buyer shall provide Seller with a tax-exemption certificate acceptable to and considered valid by the           Uniform Commercial Code. In the event of such default, Seller may, in addition to pursuing any of the remedies
applicable taxing authorities.                                                                                           provided by law, equity or as set forth in this Agreement, refuse to provide warranty, repair and/or maintenance
                                                                                                                         Service and/or deliver Products under this or any Service or maintenance agreement relating to the Products, and
5. Delivery and Risk of Loss. All sales are FOB\FCA Seller’s U.S. dock. Risk of loss, destruction of or damage           may also cancel this Agreement and any pending orders without liability to Buyer. In the event of default, Seller
to the Products shall be Seller’s until delivery of the Products to a common carrier at Seller’s U.S. dock.              may also, without limiting its other remedies, terminate this Agreement and apply any and all payments received
Thereafter, title shall pass to Buyer and Buyer shall be fully responsible, and shall hold Seller harmless, for and      hereunder or otherwise from Buyer to any damages that Seller may have as a result of the breach of this
assume all risk of loss, destruction of or damage to the Products. Loss or damage to the Products after risk of loss     Agreement or otherwise. To the fullest extent permitted by law, all of Seller’s rights and remedies under this
has passed to Buyer will not release or excuse Buyer from its obligations under this Agreement to Seller,                Agreement shall be cumulative and not exclusive.
including the obligation to make full payment of the purchase price. Seller reserves the right to pack or ship orders
in the most economical manner. However, where Buyer requests special packaging or shipping, any additional               12. Reservation of Rights: The sale of Products and Services covered by this Agreement shall not confer upon
cost will be billed to and be the responsibility of Buyer.                                                               Buyer any license or right under any patents, trade secrets or other proprietary information owned or controlled by
6. Delivery Delays. Seller shall use reasonable efforts to make prompt deliveries in a commercially reasonable           Seller, or the right to otherwise utilize such proprietary information, it being specifically understood and agreed
manner. Delivery dates and estimates are, however, not guaranteed. Seller disclaims any liability or responsibility,     that all such rights are reserved to Seller.
and Buyer shall hold Seller harmless, for the late or non-delivery of Products or Services. Buyer has no right to
delay or defer delivery or acceptance.                                                                                   13. Waiver and Severability. No claim or right arising out of a breach of this Agreement can be discharged in
                                                                                                                         whole or in part by a waiver or renunciation of the claim or right unless the waiver or renunciation is supported by
7. Rejection and Revocation of Acceptance. Any rejection or revocation of acceptance of Products or Services             consideration and is in writing signed by the aggrieved party. If any term, covenant, warranty, remedy or
by Buyer must be made within thirty (30) days of delivery of such Products and Services and any attempted                condition of this Agreement, or the application thereof to any person or circumstance shall, to any extent, be held
rejection or revocation of acceptance of such Products and Services made thereafter shall be null and void unless        or deemed invalid or unenforceable, the remainder of this Agreement or the application of such term, covenant or
agreed to in writing by Seller. Failure to make a claim within such period shall be conclusive evidence that the         provision, to persons or circumstances other than those to which it is held invalid or unenforceable, shall not be
Products and Services were satisfactory in all respects and supplied in accordance with ordered specifications.          affected thereby, and each remaining term, covenant or provision of this Agreement shall be deemed valid and
8. LIMITED WARRANTY AND DISCLAIMER OF ALL OTHER WARRANTIES. (a) SELLER                                                   enforced to the fullest extent permitted by law.
WARRANTS FOR A PERIOD OF 30 DAYS COMMENCING ON THE DATE OF DELIVERY THAT THE
PRODUCTS AND SERVICES (i) MEET OR EXCEED THE WRITTEN SPECIFICATIONS SET FORTH ON                                         14. Force Majeure. Seller shall have no liability or obligation to Buyer of any kind, including, but not limited
SELLER’S ORDER ACKNOWLEDGEMENT, AND (ii) ARE FREE OF MATERIAL DEFECTS IN DESIGN                                          to, any obligation to deliver Products or provide Services, arising from any delay or failure to perform all or any
OR WORKMANSHIP. BUYER’S EXCLUSIVE REMEDY IN CONNECTION WITH THESE EXPRESS                                                part of this Agreement as a result of causes, conduct or occurrences beyond Seller’s reasonable control, including,
WARRANTIES IS THE REPAIR OR REPLACEMENT OF THE PRODUCTS OR SERVICES OR, AT                                               but not limited to, commercial impracticability, fire, flood, earthquake, lightning, storm, accidents, act of war,
SELLER’S OPTION, A REFUND OF THE PURCHASE PRICE, IF ANY, ACTUALLY PAID BY SELLER                                         terrorism, civil disorder or disobedience, act of public enemies, problems associated with transportation (including
FOR THE NONCONFORMING PRODUCTS OR SERVICES. IF BUYER OBTAINS A REFUND OF THE                                             car or truck shortages), shortages of energy or raw materials, acts or failure to act of any state, federal or foreign
PURCHASE PRICE, BUYER SHALL FIRST SHIP THE PRODUCTS SUBJECT TO THE REFUND TO                                             governmental or regulatory authorities, labor disputes, strikes, or failure of suppliers to make timely deliveries of
SELLER AND TRANSFER TITLE TO SAID PRODUCTS TO SELLER AS SOON AS PRACTICABLE.                                             materials, goods or services to Seller.
(b) EXCEPT FOR THE EXPRESS LIMITED WARRANTY SET FORTH IN THIS SECTION 8, SELLER                                          15. Indemnification. To the fullest extent permitted by law, Buyer shall defend, indemnify and hold Seller
MAKES NO EXPRESS OR IMPLIED WARRANTIES IN THIS AGREEMENT OR OTHERWISE. TO THE                                            harmless from any and all claims, demands, subrogation claims by third parties, including Buyer’s insurers,
FULLEST EXTENT PERMITTED BY LAW, SELLER DISCLAIMS ALL WARRANTIES, WRITTEN,                                               causes of action, controversy, liabilities, fines, regulatory actions, seizures of Product, losses, costs, expenses
EXPRESS OR IMPLIED, INCLUDING ALL WARRANTIES OF MERCHANTABILITY AND/OR FITNESS                                           (including, but not limited to attorneys’ fees, expert witness expenses and litigation expenses) (hereinafter
FOR A PARTICULAR PURPOSE.                                                                                                “Claim”), arising from or in connection with any Claim asserted against Seller for any damage, environmental
(C) ANALYSES ARE CARRIED OUT IN THE BEST CONDITIONS AVAILABLE TO SELLER IN                                               liability, patent or intellectual property infringement caused by Buyer’s use, modification or alteration of the
ACCORDANCE WITH TECHNOLOGY DEVELOPED BY SELLER. INTERPRETATIONS ARE BASED                                                Products, injury, death, loss, property damage, delay or failure in delivery of Seller’s Products or any other Claim,
UPON ANALYSIS RESULTS AND ON INFORMATION PROVIDED BY BUYER. INTERPRETATIONS,                                             whether in tort, contract, breach of warranty or otherwise, relating to this Agreement, the business relationship
ASSESSMENTS AND CONCLUSIONS ARE PREPARED WITH A REASONABLE DEGREE OF CARE BUT                                            between the parties, the Products or Services provided hereunder, or Buyer’s breach of this Agreement.
BUYER ACKNOWLEDGES THAT IN ANY EVENT THEY CAN ONLY BE CONSIDERED AS BEING THE                                            Notwithstanding the foregoing, Buyer has no indemnity obligation to Seller to the extent that any Claims result
SIGNATORY’S OPINION. SELLER CANNOT GUARANTEE THAT THESE WILL ALWAYS BE                                                   from the gross negligence of Seller. Buyer, for itself and its insurers, expressly waives any and all limitations or
CORRECT OR ABSOLUTE, PARTICULARLY IN VIEW OF THE CONSTANT EVOLUTION AND RE-                                              liability caps, if any, on Buyer’s contribution liability to Seller, and any and all statutory or common law lien
EVALUATION OF SCIENTIFIC KNOWLEDGE AND REGULATIONS. IN ALL CASES BUYER MUST                                              rights or Claims against Seller arising from any applicable workers compensation or disability acts, which Buyer
VERIFY THE VALIDITY OF ANY INTERPRETATIONS, ASSESSMENTS AND CONCLUSIONS                                                  might or could assert against Seller or Seller’s insurers in the event of the personal injury or death of Buyer’s
SUPPLIED BY SELLER IF IT WISES TO RELY ON THE SAME IN RESPECT OF MATTER OF                                               employees, representatives or servants. Without limiting the foregoing, Buyer, for itself and its insurers, also
IMPORTANCE AND SHALL DO SO AT ITS OWN RISK.                                                                              waives any liens, Claims or other rights it may have as a result of being subrogated to any rights of its employees,
                                                                                                                         representatives or servants.
(D) ANALYSIS RESULTS ARE PREPARED AND SUPPLIED EXCLUSIVELY FO THE USE OF BUYER
AND MAY NOT BE DIVULGED TO A THIRD PARTY WITHOUT THE PRIOR WRITTEN AGREEMENT                                             16. Relationship. The relationship between Seller and Buyer shall be that of independent contractors and neither
OF SELLER, WHICH CONSENT MAY BE WITHHELD BY SELLER IN ITS SOLE AND ABSOLUTE                                              party, its agents and employees, shall under no circumstances be deemed the employees, distributors, franchisees,
DISCRETION. IF SUCH WRITTEN CONSENT IS GIVEN BY SELLER, BUYER SHALL INDEMNIFY,                                           agents or representatives of the other party.
DEFEND AND HOLD SELLER HARMLESS FOR ANY DAMAGES ARISING OUT OF, IN CONNECTION
WITH OR RELATED TO THE DIVULGENCE OF SUCH RESULTS TO A THIRD PARTY.                                                      17. Assignment and Modification. The rights and obligations of Buyer under this Agreement shall not be
(E) EACH ANALYTICAL REPORT RELATES EXCLUSIVELY TO THE PRODUCT RECEIVED BY                                                assignable with the prior written consent of Seller. This Agreement shall not be modified, altered or amended in
SELLER AS SPECIFIED IN THE WRITTEN ACCEPTANCE OF ORDER BY SELLER. SELLER ACCEPTS                                         any respect except by a writing signed by the parties. Any variation, modification or addition to the terms set forth
NO RESPONSIBILITY, AND BUYER SHALL HOLD SELLER HARMLESS, FOR THE WAY THE SAMPLE                                          in this Agreement shall be considered a material modification and shall not be considered part of this Agreement.
WAS COLLECTED, STORED OR DELIVERED TO SELLER UNLESS SELLER HAS SPECIFICALLY
                                                                                                                         17. Governing Law. This Agreement and all claims and causes of action shall be governed by and subject to the
AGREED IN WRITING TO UNDERTAKE SUCH TASKS ITSELF.
                                                                                                                         internal laws (exclusive of the conflicts of law provisions) and decisions of the courts of the State of California.
(F) SELLER ACCEPTS NO RESPONSIBILITY, AND BUYER SHALL HOLD SELLER HARMLESS, FOR                                          The sole and exclusive venue for all claims and causes of action between the parties shall be the state or federal
ANY LOSS OR DAMAGE THAT MAY OCCUR TO ANY SAMPLE IN TRANSIT. BUYER WILL AT ALL                                            court located in Orange County, California.
TIMES BE LIABLE FOR THE SECURITY, PACKAGING, AND INSURANCE OF THE SAMPLE FROM ITS
DISPATCH UNTIL IT IS DELIVERED TO THE OFFICE OR LABORATORIES OF SELLER. SELLER                                           By                                                                           Date:
WILL USE COMMERCIALLY REASONABLE CARE IN HANDING AND STORING SAMPLES, BUT
SELLER SHALL NOT BE HELD RESPONSIBLE, AND BUYER SHALL HOLD SELLER HARMLESS, FOR                                               Its:
ANY LOSS OR DESTRUCTION OF SAMPLES EVEN AFTER THEIR RECEIPT AT ITS LABORATORIES.

                Tel. (949) 419-0288                            Fax. (949) 419-0294                             email. sales@chromadex.com                                 www.chromadex.com
2




           tel. 949.419.0288 fax. 949.419.0294 email. sales@chromadex.com




    Tel. (949) 419-0288   Fax. (949) 419-0294   email. sales@chromadex.com   www.chromadex.com

				
DOCUMENT INFO
Shared By:
Categories:
Stats:
views:134
posted:6/22/2011
language:Italian
pages:48