Global Spinal Surgical Devices Market by ylh54231

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Spinal Surgery - Global Strategic Business Report

Description:    This report analyzes the worldwide markets for Spinal Surgery in Millions of US$ by the following
                segments: Spinal Fusion Devices, Spinal Fixation Devices, Artificial Discs, and Vertebral
                Compression Fracture Devices. The report provides separate comprehensive analytics for the US,
                Europe, Asia-Pacific and Rest of World. Annual forecasts are provided for each region for the period
                of 2005 through 2015. The report profiles 92 companies including many key and niche players
                worldwide such as Alphatec Spine Inc., Altiva Corporation Inc., ArthroCare Corporation, Biomet,
                Inc., Depuy Spine Inc., Medtronic Inc., Medtronic Sofamor Danek, Inc., Kyphon, Inc., NuVasive
                Inc.,. Orthofix International N.V., Orthovita Inc., SCIENTX SA, Smith & Nephew Plc, SpineVision,
                Stryker Corporation, Synthes Inc., and Zimmer Spine Inc. Market data and analytics are derived
                from primary and secondary research. Company profiles are mostly extracted from URL research
                and reported select online sources.


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Contents:       I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

                Study Reliability and Reporting Limitations I-1
                Disclaimers I-2
                Data Interpretation & Reporting Level I-2
                Quantitative Techniques & Analytics I-3
                Product Definitions and Scope of Study I-3
                Spinal Surgery I-3
                Spinal Fusion Devices I-3
                Spinal Fixation Devices I-3
                Artificial Discs I-3
                Vertebral Compression Fracture Devices I-3


                II. Executive Summary

                1. INDUSTRY OVERVIEW II-1
                Regional Perspective II-1
                Product Segment Perspective II-1
                Aging Population Drives Demand II-1
                Table 1: Select Musculoskeletal Conditions - Percentage
                Breakdown by Age Group (includes corresponding Graph/Chart) II-2
                Table 2: World Demographic Trends: 65+ Group as a Percentage
                of Total Population by Geographic Region - US, Canada, Japan,
                Europe, Asia-Pacific, and Latin America for years 2000, 2008,
                2010, and 2020 (includes corresponding Graph/Chart) II-3
                Spinal Surgery Market: Primary Growth Drivers II-3
                Spinal Surgery: The Last Resort II-3
                Risks Associated with Spinal Surgery: II-4
                Spinal Surgery Alternatives II-4
                Spinal Decompression with a ‘Herniated Disc Device II-5
                Pain Relief Medications II-5

                2. MARKET DYNAMICS II-6
Spinal Fusion Devices Taking Back Seat II-6
Innovations to Sustain Growth in Fusion Process II-6
Artificial Disc Replacement: An Ideal Alternative to Spinal
Fusion II-6
Minimally Invasive Procedures Gain Prominence II-6
MIS Spinal Fusion - Another Prospective Avenue II-7
Microscopic Surgeries-A Key Development II-7
Growing Presence of Mid-Tier Firms & Start-Ups in Spinal Segment II-7

3. COMPETITION II-8
Table 3: Leading Players in the Global Spinal Surgery Market
(2008 E): Percentage Share Breakdown of Revenues for
Medtronic/Kyphon ,D ePuy, Synthes, Stryker, Biomet, Zimmer and
Others (includes corresponding Graph/Chart) II-8
Vertebral Compression Fracture II-8
Disc Replacement Devices II-8
Select Artificial Discs Available in the Market or in
Development, 2008 II-9
Review of Select Artificial Discs II-9
Bryan Cervical Artificial Disc II-9
Prestige Cervical Disc II-10
Cervitech PCM Disc II-10
Prodisc-C Artificial Cervical Disc II-10
Cervicore Artificial Cervical Disc II-10
Mobi-C Artificial Cervical Disc II-10
SECURE-C Artificial Cervical Disc II-11
Kineflex-C Artificial Cervical Disc II-11
Consolidation Moves II-11
Review of Select Recent Strategic Acquisitions II-11

4. ANATOMY OF THE SPINE II-12
Back Pain - A Warning Signal II-12
What Causes Back Pain? II-12
Herniated Disc II-12
Degenerative Disc Disease II-13
Osteophytes or Bone Spurs II-13
Lumbar Spinal Stenosis II-13
Osteroprosis II-13
Osteoarthritis II-13
Cervical Spondylosis II-13
Scoliosis II-14
Strains and Sprains II-14
Compression Fractures II-14
Vertebral Fractures II-14
Precise Cause of Pain: Still Untraceable II-14
Cervical Spine Disorders II-14
Disc Herniation II-14
Spinal Stenosis II-14

5. SPINAL SURGERY - AN INSIGHT II-15
Spinal Surgery II-15
Lumbar Spine Surgery II-15
Cervical Spine Surgery II-15
Minimally invasive Spinal Surgeries II-16
Recuperation After Surgery II-17
Novel Innovations Aid in Reduced Pain and Faster Recovery II-17
Factors Conducive to Faster Recovery II-17
Classification of Spinal Surgery II-17
Classification By Technology II-17
Spinal Fusion II-17
Solid Fusion II-18
Factors Influencing Solid Fusion II-18
Disadvantages of Spinal Fusion II-18
Minimally Invasive Spine Fusion: An Overview II-19
Minimally Invasive Frontal Approach II-19
Approach to Interbody Fusion Surgery II-20
Posterior Lumbar Interbody Fusion (PLIF) II-20
Anterior Lumbar Interbody Fusion (ALIF or TLIF or from the
front) II-20
Non-fusion/Motion Preservation Technologies II-20
Total Disc Replacement (TDR) II-21
Nucleus Arthroplasty Motion Preservation System II-21
Select Companies with Nucleus Arthroplasty Devices Under
Development II-22
Dynamic Stabilization II-22
Facet Joint Replacement II-23

6. A BACKDROP OF SELECT PRODUCTS AND DEVICES INVOLVED II-24
SPINAL FUSION DEVICES II-24
Spinal Fixation Devices II-24
Artificial Discs II-24
Vertebral Compression Fracture Devices II-24
Other Devices and Materials II-25
Bone Grafts II-25
Bone Graft Substitutes and Enhancers II-26
Demineralized Bone matrix (DBM) II-26
Platelet-derived Growth Factors II-26
Bone Morphogenetic Proteins (BMPs) II-26

7. REVIEW OF SELECT SPINAL SURGERY AND TREATMENT PROCEDURES II-27
VERTEBROPLASTY II-27
Kyphoplasty II-27
Intradiscal Electrothermal Annuloplasty (IDET) II-27
Endoscopic Spine Surgery II-28
Percutaneous Discectomy II-28
Foraminotomy II-28
Laminectomy II-29
Facet Thermal Ablation II-30
Disc Decompression II-30
Video-assisted thoracic surgery (VATS) II-31
Gene Therapy II-31
Table 4: Global Spinal Surgery Market (2009 E): Percentage
Share Breakdown of Surgical Procedures - Spine Fusion, Bone
Graft Substitutes, Disc Replacements, Image Guided Surgery,
Vertebroplasty/Kyphoplasty, Nucleus Replacements, and Others
(includes corresponding Graph/Chart) II-31

8. PRODUCT DEVELOPMENT / APPROVAL/ LAUNCHES II-32

FDA APPROVES MEDTRONIC SOFAMOR’S PREMARKET APPROVAL Application
for Bryan Cervical Disc II-32
Pioneer Surgical Receives FDA Approval for IDE pivotal study
of NuBac Implant II-32
Scientx Introduces Novel Cage System II-32
DePuy Spine Introduces EAGLE™ Plus and SWIFT™ Plus ACP Systems II-33
Medtronic Rolls out Discyphor DirectTM Catheter System II-33
US Spine Receives FDA Approval for Preference 2 Complex Spine
System II-33
Scient’x Receives USFDA Approval for Isobar DUO™ Dynamic
Stabilization System II-34
Osteotech Obtains USFDA Approval for Plexur M™ Biocomposite II-34
Orthofix Receives FDA Approval for Firebird Spinal Fixation
Device II-34
LDR Introduces verteBRIDGE TM Anchoring Technology II-34
LDR Releases ROI-T TM II-35
LDR Releases ROI-A™ II-35
DePuy Spine Launches CONCORDETM Bullet Vertebral Body Replacement II-35
DePuy Spine Introduces the EXPEDIUM™ 4.5 Spine System II-36
DePuy Spine Launches VIPER™2 Pedicle Screw Fixation System II-36
DePuy Spine Introduces EXPEDIUM™ PEEK Rod System II-37
DePuy Spine Unveils CONFIDENCE SPINAL CEMENT SYSTEM™ II-37
DePuy Spine Introduces Latest Anterior Cervical Plating Systems II-37
Alphatec Holdings Introduces DYNAMO Semi-Rigid Spinal System II-38
Integra LifeSciences Introduces a Smaller Variant of the
Accell TBM® II-38
Scientx Introduces TribecaTM Cage System II-38
Princess Grace Releases Balloon Kyphoplasty II-39
Health Canada Approves the use of FzioMed’s Oxiplex® Gel II-39
Pioneer Surgical Launches Cross-FuseTM Lateral Option System II-39
Globus Introduces Niko Spacer System II-39
X-spine Receives USFDA Approval for BUTREX Buttress Plating
System II-40
K2M Launches Lumbar Spacer Systems II-40
Medtronic Launches Image-Guided Spinal Surgery System II-40
Synergetics Introduces Ultrasonic Aspirator for Spinal Surgeries II-40
Integra LifeSciences Receives FDA Approval for Integra Mozaik™
Osteoconductive Scaffold II-41
Medtronic Unveils CD Horizon® LongitudeTM Multi-level
Percutaneous Fixation System II-41
Spine Wave Receives FDA Approval for CapSure™ PS Spine System II-41
Synthes Receives FDA Approval for ProDisc®-C II-41
Synthes Receives FDA Approval for chronOS™ Strip II-42
Theken Spine Develops Unique Spinal Pedicle Screw in
Collaboration with a Surgeon II-42
DePuy Spine Launches VERTIGRAFT VG2 TLIF Allograft II-42
DePuy Spine Launches EXPEDIUM™ SFX™ Cross Connector system II-43
DePuy Spine Launches AEGIS Anterior Lumbar Plate System II-43
DePuy Spine Launches EXPEDIUM 6.35 Screw and Rod System II-43
Abbott Introduces Universal Clamp™ Spinal Fixation System II-44
HydroCision Introduces New SpineJet XL® Fusion Instruments II-44
Innovative Spinal Technologies Launches Paramount VBR System II-44
Alphatec Holdings Launches New NOVEL-TL Spinal Spacer System II-44
Biomet Orthopedics Introduces Two New Hip Stems II-45
Alphatec Launches CONNECT II Cervical Structural Allograft Spacer II-45
Pioneer Surgical Releases Quantum MIS Rodding System II-46
Spinal Elements Rolls out MercuryTM Spinal System II-46
K2M Introduces SERENGETI™ Minimally Invasive Retractor System II-46
Theken Spine Secures FDA Approval for Two of its Products II-47
Vertebration Receives FDA Approval for its XycorTM Spinal Implant II-47
Medtronic Launches PRESTIGE Artificial Disc II-47
X-spine Secures Approval from the FDA to Market its Capless LI
™ Pedicle Screw System II-47
Theken Spine to Introduce Two New Products II-48
Imaging3 to Launch Dominion Real-Time 3D Imaging Device II-48
US Surgical Receives USFDA Approval for Ray TFC II-48
NuVasive Introduces New Spinal Surgery Devices II-49
Medtronic Introduces Spine Stabilizing Rod II-49
Globus Medical Launches XPand R II-49
Innovative Spinal Technologies Launches Paramount Pedicle
Screw System II-50
Medtronic Launches CD HORIZON SPIRE™ II-50
SpineVision Launches FlexPLUS II-50
Abbott Introduces New Harmony Retractor Minimally Invasive
Access System II-50
NuVasive Unveils Gradient PlusTM Anterior Cervical Plating System II-51
Medtronic Introduces CD HORIZON® LEGACYTM 4.5 Spinal System II-51
Medtronic Receives TGA Approval for Three Devices II-52

9. RECENT INDUSTRY ACTIVITY II-53
NuVasive to Take Over Cervitech II-53
Norman Noble Expands Production Facility II-53
Osteotech Enters into Distribution Agreement with Harvest II-53
Orthofix Purchases IP of an Advanced Spinal System from IIS II-54
Integra LifeSciences Takes Over Theken II-54
Exactech Acquires Altiva II-54
Spineology Secures US$7.5 million for Expansion II-54
Encore Medical Division Changes Name to DJO Surgical II-54
Alphatec Spine Enters into Agreement with Stout Medical II-55
Zimmer Takes over Abbott Spine II-55
Scient’x Repurchases Isobar License from Alphatec Spine II-55
Bonati Institute Starts New Spine Center in Chile II-56
Mubadala Healthcare Enters into Agreement with the Wooridul
Spine Hospital II-56
Interventional Spine and Dr. Rudolf Morgenstern Sign Agreement
for PNSS II-56
VSCI Inks a Development and Supply Agreement with SpineView II-56
NuVasive Acquires Osiris Therapeutics’ Osteocel Biologics
Business II-56
Bonesupport Takes Over Ultrazonix II-57
Biomet Merges with LVB Acquisition Merger Sub II-57
Zimmer Holdings Acquires Endius II-57
Cytovance Biologics Inks Agreement with Bone Biologics II-58
Alphatec Inks Agreement with Scientx II-58
Kyphon Acquires St. Francis Medical Technologies II-58
NuVasive Acquires Biologic Product Technology from Radius Medical II-58
ReAble Therapeutics and DJO Complete Merger Transaction II-58
Pioneer Surgical Takes Over Angstrom Medica II-59
Integra LifeSciences Takes Over IsoTis II-59
TriMas Takes Over DEW Technologies II-59
Osteotech and Novation Sign Single Source Agreement II-59
Medtronic Takes Over Kyphon II-60
Biomet Sports Medicine and Marc Tec Enter into Licensing
Agreement II-60
Synthes Acquires N Spine II-60
Pioneer Surgical Takes Over Encelle II-60
Integra LifeSciences to Take Over Physician Industries II-61
TriMas Takes Over DEW Technologies II-61
ASC Enters into an Agreement with PTG II-61
Medtronic and Axon Systems Enter into Agreement II-61
Sandvik Acquires JKB Medical Technologies II-61
Alphatec Spine Acquires Exclusive Global License to Develop V
-Stent II-62
Alphatec Spine Enters into Licensing Agreement with JGMG
Bengochea II-62
Smith & Nephew and Teknimed Ink Distribution Agreement II-62
Scient’x Opens Regional Office in Singapore II-63
Medtronic and Shandong Weigao to Establish Joint Venture in China II-63
DePuy Spine Inks Acquisition Agreement with Disc-O-Tech II-63
Sandvik Acquires Medtronics Medical Instrumentation Plant II-64
Sandvik Takes Over Doncasters Medical Technologies II-64
Kensey Nash Acquires MacroPore Biosurgery II-64
Healthcor Associates Acquires Stake in Paradigm Spine II-65
X-spine Receives Patent for Disk Augmentation System II-65
Orthofix Acquires Blackstone Medical II-65
NuVasive Receives IDE Approval for NeoDisc Clinical Trial II-65
LDR Merges LDR Spine and LDR Medical to Form LDR Holding
Corporation II-66
Orthofix International Enters into an Agreement with
UnitedHealthcare II-66
Blackstone Medical and Regeneration Technologies Sign
Production Agreement II-66
Kyphon Acquires Disc-O-Tech II-67
10. FOCUS ON SELECT PLAYERS II-68
Alphatec Spine Inc. (US) II-68
Altiva Corporation Inc. (US) II-68
ArthroCare Corporation (US) II-68
Biomet, Inc. (US) II-69
Depuy Spine Inc. (US) II-69
Medtronic Inc. (US) II-70
Medtronic Sofamor Danek, Inc. (US) II-70
Kyphon, Inc. (US) II-70
NuVasive Inc. (US) II-70
Orthofix International N.V. (US) II-71
Orthovita Inc. (US) II-71
SCIENTX SA (France) II-72
Smith & Nephew Plc (UK) II-72
SpineVision (France) II-72
Stryker Corporation (US) II-72
Synthes Inc. (US) II-73
Zimmer Spine Inc. (US) II-73

11. GLOBAL MARKET PERSPECTIVE II-75
Table 5: World Recent Past, Current & Future Market Analysis
for Spinal Surgery Devices by Geographic Region -US, Europe,
Asia-Pacific and Rest of World Independently Analyzed with
Annual Sales Figures in US$ million for Years 2005 through
2015 (includes corresponding Graph/Chart) II-75

Table 6: World 11-Year Perspective for Spinal Surgery Devices
by Geographic Region - Percentage Breakdown of Dollar Sales
for US, Europe, Asia-Pacific and Rest of World Markets for
Years 2005, 2009 & 2015 (includes corresponding Graph/Chart) II-76

Table 7: World Recent Past, Current & Future Market Analysis
for Spinal Fusion Devices by Geographic Region -US, Europe,
Asia-Pacific and Rest of World Independently Analyzed with
Annual Sales Figures in US$ million for Years 2005 through
2015 (includes corresponding Graph/Chart) II-77

Table 8: World 11-Year Perspective for Spinal Fusion Devices
by Geographic Region - Percentage Breakdown of Dollar Sales
for US, Europe, Asia-Pacific and Rest of World Markets for
Years 2005, 2009 & 2015 (includes corresponding Graph/Chart) II-78

Table 9: World Recent Past, Current & Future Market Analysis
for Spinal Fixation Devices by Geographic Region -US, Europe,
Asia-Pacific and Rest of World Independently Analyzed with
Annual Sales Figures in US$ million for Years 2005 through
2015 (includes corresponding Graph/Chart) II-79

Table 10: World 11-Year Perspective for Spinal Fixation
Devices by Geographic Region - Percentage Breakdown of Dollar
Sales for US, Europe, Asia-Pacific and Rest of World Markets
for Years 2005, 2009 & 2015 (includes corresponding
Graph/Chart) II-80

Table 11: World Recent Past, Current & Future Market Analysis
for Artificial Discs by Geographic Region -US, Europe,
Asia-Pacific and Rest of World Independently Analyzed with
Annual Sales Figures in US$ million for Years 2005 through
2015 (includes corresponding Graph/Chart) II-81

Table 12: World 11-Year Perspective for Artificial Discs by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Europe, Asia-Pacific and Rest of World Markets for Years
2005, 2009 & 2015 (includes corresponding Graph/Chart) II-82

Table 13: World Recent Past, Current & Future Market Analysis
for Vertebral Compression Fracture Devices by Geographic
Region -US, Europe, Asia-Pacific and Rest of World
Independently Analyzed with Annual Sales Figures in US$
million for Years 2005 through 2015 (includes corresponding
Graph/Chart) II-83

Table 14: World 11-Year Perspective for Vertebral Compression
Fracture Devices by Geographic Region - Percentage Breakdown
of Dollar Sales for US, Europe, Asia-Pacific and Rest of World
Markets for Years 2005, 2009 & 2015 (includes corresponding
Graph/Chart) II-84


III. MARKET

1. THE UNITED STATES III-1
A.Market Analysis III-1
Market Statistics III-1
Spinal Products Market III-1
Low Back Pain Prevalent in the US III-2
Spinal Procedures in US Witness Substantial Growth III-2
Table 15: Spinal Implant Procedures in the US: 2001-2008E
(includes corresponding Graph/Chart) III-3
Vertebral Compression Fracture Devices Market On Growth Spree III-3
Table 16: Kyphoplasty Procedures in the US (2006 -2010P) (
includes corresponding Graph/Chart) III-3
Minimally Invasive Spinal Surgery Market: An Overview III-3
Facet Fixation Market: Driven by Innovation III-4
Disc Replacements: The New Buzz III-4
Competition III-4
Spinal Fusion Market III-5
Table 17: Leading Players in the US Spinal Fusion Devices
Market (2008): Percentage Share Breakdown of Revenues for
Medtronic, DePuy Spine, Stryker Spine, Zimmer, Biomet and
Others (includes corresponding Graph/Chart) III-5
Spinal Fixation Market III-5
Table 18: Leading Players in the US Spinal Fixation Devices
Market (2008): Percentage Share Breakdown of Revenues for
Medtronic, DePuy Spine, Synthes, Stryker Spine, Biomet,
Zimmer and Others (includes corresponding Graph/Chart) III-5
Vertebral Compression Fracture Devices Market III-6
Reimbursement Scenario III-6
Product Approval/Launches III-7
Strategic Corporate Developments III-26
Review of Major Players III-38
B.Market Analytics III-44
Table 19: US Recent Past, Current & Future Market Analysis
for Spinal Surgery Devices by Product Segment - Spinal
Fusion Devices, Spinal Fixation Devices, Artificial Discs
and Vertebral Compression Fracture Devices Markets
Independently Analyzed with Annual Sales Figures in US$
million for Years 2005 through 2015 (includes corresponding
Graph/Chart) III-44

Table 20: US 11-Year Perspective for Spinal Surgery Devices
by Product Segment - Spinal Fusion Devices, Spinal Fixation
Devices, Artificial Discs and Vertebral Compression Fracture
Devices Markets for 2005, 2009 & 2015 (includes
corresponding Graph/Chart) III-45
2. EUROPE III-46
A.Market Analysis III-46
Market Overview III-46
B.Market Analytics III-47
Table 21: European Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Product Segment -
Spinal Fusion Devices, Spinal Fixation Devices, Artificial
Discs and Vertebral Compression Fracture Devices Markets
Independently Analyzed with Annual Sales Figures in US$
million for Years 2005 through 2015 (includes corresponding
Graph/Chart) III-47

Table 22: European 11-Year Perspective for Spinal Surgery
Devices by Product Segment - Spinal Fusion Devices, Spinal
Fixation Devices, Artificial Discs and Vertebral Compression
Fracture Devices Markets for 2005, 2009 & 2015 (includes
corresponding Graph/Chart) III-48

Table 23: European Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Geographic Region -
France, Germany, Italy, UK and Rest of Europe Markets
Independently Analyzed with Annual Sales Figures in US$
million for Years 2005 through 2015 (includes corresponding
Graph/Chart) III-49

Table 24: European 11-Year Perspective for Spinal Surgery
Devices by Geographic Region - Percentage Breakdown of
Dollar Sales for France, Germany, Italy, UK and Rest of
Europe Markets for Years 2005, 2009 & 2015 (includes
corresponding Graph/Chart) III-50

2a. FRANCE III-51
A.Market Analysis III-51
Product Approval/Launches III-51
Strategic Corporate Developments III-52
Review of Major Players III-52
B.Market Analytics III-53
Table 25: French Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Product Segment -
Spinal Fusion Devices, Spinal Fixation Devices and Vertebral
Compression Fracture Devices Markets Independently Analyzed
with Annual Sales Figures in US$ million for Years 2005
through 2015 (includes corresponding Graph/Chart) III-53

Table 26: French 11-Year Perspective for Spinal Surgery
Devices by Product Segment - Spinal Fusion Devices, Spinal
Fixation Devices and Vertebral Compression Fracture Devices
Markets for 2005, 2009 & 2015 (includes corresponding
Graph/Chart) III-54

2b. GERMANY III-55
Market Analysis III-55
Table 27: German Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Product Segment -
Spinal Fusion Devices, Spinal Fixation Devices and Vertebral
Compression Fracture Devices Markets Independently Analyzed
with Annual Sales Figures in US$ million for Years 2005
through 2015 (includes corresponding Graph/Chart) III-55

Table 28: German 11-Year Perspective for Spinal Surgery
Devices by Product Segment - Spinal Fusion Devices, Spinal
Fixation Devices and Vertebral Compression Fracture Devices
Markets for 2005, 2009 & 2015 (includes corresponding
Graph/Chart) III-56

2c. ITALY III-57
Market Analysis III-57
Table 29: Italian Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Product Segment -
Spinal Fusion Devices, Spinal Fixation Devices and Vertebral
Compression Fracture Devices Markets Independently Analyzed
with Annual Sales Figures in US$ million for Years 2005
through 2015 (includes corresponding Graph/Chart) III-57

Table 30: Italian 11-Year Perspective for Spinal Surgery
Devices by Product Segment - Spinal Fusion Devices, Spinal
Fixation Devices and Vertebral Compression Fracture Devices
Markets for 2005, 2009 & 2015 (includes corresponding
Graph/Chart) III-58

2d. THE UNITED KINGDOM III-59
A.Market Analysis III-59
Product Approval/Launches III-59
Strategic Corporate Developments III-59
Smith & Nephew Plc - A Key Player III-60
B.Market Analytics III-61
Table 31: United kingdom Recent Past, Current & Future
Market Analysis for Spinal Surgery Devices by Product
Segment - Spinal Fusion Devices, Spinal Fixation Devices and
Vertebral Compression Fracture Devices Markets Independently
Analyzed with Annual Sales Figures in US$ million for Years
2005 through 2015 (includes corresponding Graph/Chart) III-61

Table 32: United Kingdom 11-Year Perspective for Spinal
Surgery Devices by Product Segment - Spinal Fusion Devices,
Spinal Fixation Devices and Vertebral Compression Fracture
Devices Markets for 2005, 2009 & 2015 (includes
corresponding Graph/Chart) III-62

2e. REST OF EUROPE III-63
A.Market Analysis III-63
Review of Select Regions III-63
Czech Republic III-63
Hungary III-63
Strategic Corporate Developments III-63
B.Market Analytics III-64
Table 33: Rest of European Recent Past, Current & Future
Market Analysis for Spinal Surgery Devices by Product
Segment - Spinal Fusion Devices, Spinal Fixation Devices and
Vertebral Compression Fracture Devices Markets Independently
Analyzed with Annual Sales Figures in US$ million for Years
2005 through 2015 (includes corresponding Graph/Chart) III-64

Table 34: Rest of European 11-Year Perspective for Spinal
Surgery Devices by Product Segment - Spinal Fusion Devices,
Spinal Fixation Devices and Vertebral Compression Fracture
Devices Markets for 2005, 2009 & 2015 (includes
corresponding Graph/Chart) III-65

3. ASIA-PACIFIC III-66
A.Market Analysis III-66
Asia-Pacific: A Promising Market for Spinal Implants III-66
Key Players Eye Asia III-66
Overview of the Minimally Invasive Surgery Market III-66
Competition III-66
Table 35: Leading Players in the Asia-Pacific Spinal
Surgery Market (2008): Percentage Share Breakdown of
Revenues for Medtronic, Synthes, DePuy, Stryker, Zimmer and
Others (includes corresponding Graph/Chart) III-67
Review of Select Regions III-67
Japan III-67
Market Analysis III-67
Market Overview III-67
Table 36: Japanese Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Product Segment -
Spinal Fusion Devices, Spinal Fixation Devices and
Vertebral Compression Fracture Devices Markets
Independently Analyzed with Annual Sales Figures in US$
million for Years 2005 through 2015 (includes
corresponding Graph/Chart) III-68

Table 37: Japanese 11-Year Perspective for Spinal Surgery
Devices by Product Segment - Spinal Fusion Devices,
Spinal Fixation Devices and Vertebral Compression
Fracture Devices Markets for 2005, 2009 & 2015 (includes
corresponding Graph/Chart) III-68
China III-69
Thailand III-69
Product Approval / Launches III-69
Strategic Corporate Developments III-70
B.Market Analytics III-71
Table 38: Asia-Pacific Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Product Segment -
Spinal Fusion Devices, Spinal Fixation Devices, Artificial
Discs and Vertebral Compression Fracture Devices Markets
Independently Analyzed with Annual Sales Figures in US$
million for Years 2005 through 2015 (includes corresponding
Graph/Chart) III-71

Table 39: Asia-Pacific 11-Year Perspective for Spinal
Surgery Devices by Product Segment - Spinal Fusion Devices,
Spinal Fixation Devices, Artificial Discs and Vertebral
Compression Fracture Devices Markets for 2005, 2009 & 2015
(includes corresponding Graph/Chart) III-72

4. REST OF WORLD III-73
A.Market Analysis III-73
Strategic Corporate Developments III-73
B.Market Analytics III-75
Table 40: Rest of World Recent Past, Current & Future Market
Analysis for Spinal Surgery Devices by Product Segment -
Spinal Fusion Devices, Spinal Fixation Devices, Artificial
Discs and Vertebral Compression Fracture Devices Markets
Independently Analyzed with Annual Sales Figures in US$
million for Years 2005 through 2015 (includes corresponding
Graph/Chart) III-75

Table 41: Rest of World 11-Year Perspective for Spinal
Surgery Devices by Product Segment - Spinal Fusion Devices,
Spinal Fixation Devices, Artificial Discs and Vertebral
Compression Fracture Devices Markets for 2005, 2009 & 2015
(includes corresponding Graph/Chart) III-76


IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 92 (including Divisions/Subsidiaries - 122)
            ------------------------------------------
            Region/Country Players
            ------------------------------------------
            The United States 85
            Canada 1
            Japan 4
            Europe 24
            Germany 6
            The United Kingdom 9
            Rest of Europe 9
            Asia-Pacific (Excluding Japan)2
            Middle East 4
            Latin America 1
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