mannitol by dredwardmark



induces diuresis mainly by elevating the osmotic pressure of the glomerular filtrate to such an extent that the tubular reabsorption of water and solutes is hindered.

Cerebral edema, edema, hemolysis prevention, ocular hypertension, prevention and/or treatment of the oliguric phase of acute renal failure, may prevent or reverse acute functional renal failure before there is evidence of tubular necrosis or multiple vascular thrombosis

To reduce intracranial pressure: 1.5–2 g/kg administered as a 15, 20, or 25% solution over a period of 30–60 minutes

Hypersensitivity, kidney problems, liver problems (e.g., cirrhosis), heart disease, lung or breathing problems (e.g., pulmonary edema), nervous system problems, chemical disorders (e.g., acid/base balance, electrolyte disorders

lithium, aminoglycoside antibiotics

More Frequent: dry mouth, nausea, polydipsia, headache, polyuria, vomiting. Less Frequent: blurring of vision, dizziness, hives, skin rash. Rare or Very Rare: allergic dermatitis, allergic reactions, chest pain, chills, difficulty urination, electrolyte imbalance, fever, pulmonary congestion, renal failure, swelling of feet or legs, tachycardia, thrombophlebitis

5%, 10%, 15%, 20%, 25% parenteral injection

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