This is the tendency to maintain stability or uniformity in an organism’s internal environment. An internal balance is maintained of body temperature and of chemicals such as water , glucose , urea salts carbon dioxide homeostasis involves both the nervous and endocrine systems. The simple sugar that serves as the main source of energy in the body. Glucose is the principal sugar the body makes. The body makes glucose from proteins, fats and, in largest part, carbohydrates. Glucose is carried to each cell through the bloodstream. Cells, however, cannot use glucose without the help of insulin. Glucose is also known as dextrose. In animals such as ourselves, the internal environment of our bodies must have certain conditions within a tolerance level to continue the healthy functioning of our body. This is done by a process called negative feedback control, where different receptors and effectors bring about a reaction to make sure that such conditions remain under control. Negative Feedback Mechanisms: Are the most common they are stimulus response mechanisms in which the response produced decreases the original stimulus. When the body sweats it cools the body down to its preferred temperature to 37 degrees. Positive Feedback Mechanisms: Are those which the stimulus causes the change that increases rather than decreases back to the original stimulus's. A positive feedback would be the action of a potential nerve cell. Diabetes is a disorder of the metabolism, the way our bodies uses food for growth and energy. Most of the food we eat is broken down into glucose, and creates sugar in our blood. Glucose is the main component of fuel for the body. After digestion, glucose goes through the bloodstream, where it is used by cells for growth and energy. For glucose to get into cells, insulin must be provided. Insulin is a hormone made by the pancreas, it is a large gland behind the stomach. When we eat, the pancreas automatically makes the right amount of insulin to move glucose from blood into our cells. In people with diabetes the pancreas either makes little or no insulin, or the cells do not respond well to the insulin that is produced. Glucose builds up in the blood, overflows into the urine, and passes out of the body. Either way, the body loses its main source of fuel even though the blood contains large amounts of sugar. Type 1: Diabetes is generally genetic, which is known as type 1 diabetes. Type 2: This type of Diabetes can usually be healed by healthy diet and fitness . 1. EAT WISELY! 2. GET MOVING! 3. SAY HELLO TO THE SUN! 4. SHED THOSE EXTRA KILOS! 5. TAKE GLUCOSE-BALANCE! The body requires volumes of glucose in order to make ATP. Two hormones are responsible for controlling the concentration of glucose in the blood. These are insulin and glucagon. The diagram shows the principle of negative feedback control in action involving blood/sugar levels. The receptors of the pancreas are in charge for controlling the glucose levels in the bloodstream. Two types of cells release two different hormones from the pancreas, insulin and glucagon. These hormones target the liver, one or the other depending on the glucose concentration. When glucose levels increase, less glucagon and more insulin is released by the pancreas and targets the liver . In cases where glucose levels decrease, less insulin and more glucagon is released by the pancreas and targets the liver The liver acts as a storage place for glycogen, the storage form of glucose. When glycogen or insulin hormones aim for the liver, the following occurs; Insulin - Insulin is released to the increase of glucose levels, therefore it converts the glucose into glycogen, which is stored in the liver to be used in a later date. Glucagon - Glucagon is released as a result of a decrease in glucose levels, and promotes the conversion of glycogen into glucose, where the lack glucose can be made up for by the new supply of glucose brought about from glycogen. The amount of glucose in your blood is carefully controlled. Again, this uses the hormonal system. The hormones responsible for regulating blood glucose are produced in the pancreas in particular areas called Islets of Langerhans.