The Night Eating Syndrome

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					The Night Eating Syndrome

            By: Beth Magana
What is the Night Eating

   Caused primarily by stress and depression

   A delay in the Circadian pattern of food

   When an individual cant control waking up to
    eat in the middle of the night.
Quick Facts

   Affects about 1 percent to 2 percent of the general population.

   Both men and women are affected, with women representing about 60
    percent of sufferers and men about 40 percent.

   The hypothalamus, pituitary and adrenal glands may be chronically
    over stimulated in people with night eating syndrome.
NOT to be confused with
Sleep-Related Eating Syndrome

   A Parasomnia, and rare type of sleepwalking, a disorder or arousal.

   Lack of conscious awareness during nocturnal eating episodes, with
    associated amnesia the following day.
What are the Symptoms?

   Hyperphagia
                                   The eating produces feelings of
                                    guilt and shame, not enjoyment.
   Morning anorexia
                                   Especially at night the individual
                                    may be moody, tense, anxious,
   Trouble falling asleep or       or agitated.
    staying asleep.
Who is affected?

   The disorder occurs predominantly among obese individuals, during
    periods of stress, and tends to remit of stress is alleviated.

   However, it is also seen in individuals at their ideal body weight. The
    inability to gain weight is not known entirely.
There’s Different Types of Night

   The compelled evening and nighttime overeater

   The anxious/agitated night eater

   The cravings night eater

   The all-or-nothing belief about sleep night eater
Why does this occur in some

   People with this condition are       NES individuals had lower
    under stress, either recognized       nighttime serum melatonin.
    or hidden.
   Their bodies are flooded with        Smaller nighttime rise in Leptin.
    Cortisol, a stress hormone.
                                         Plain and simple: Their bodies
                                          just can’t cope with stress like
                                          they should.
   Leptin falls in response to fasting or weight loss.
   Ghrelin increases before meals in normal subjects and is
    suppressed by feeding.
   Melatonin peaks during the first half of the night.
   Cortisol and prolactin are both increased by stress
   Cortisol peaks in the morning while prolactin peaks during the
    latter part of the sleep period and declines upon awakening.
   Thyroid stimulating hormone (TSH) peaks in the late evening
    and is suppressed by sleep.
Hormones Activity in NES Subjects

   Insulin was higher at night and lower in the morning for NES subjects.
   Ghrelin levels showed a pattern opposite of that of insulin, lower in the
    early morning hours.
   Leptin and melatonin levels increased at night in NES subjects.
   Cortisol was highest in the morning and declined at night.
   There was a trend for TSH levels to be higher in NES subjects than in
    controls, especially in the early morning.
Average Caloric Intake
Treatment Options

   Sertaline

   Stress-reduction programs, including mental health
    therapy, seem to help
Awakenings Before and After
   Marshall, H., Kelly, A., O’Reardon, J., Birketvedt, G., Stunkard, A. Night Eating Syndrome
    among Nonobese Persons. (2003)Int J Eat Disord 35: 217–222
   Allison, K., Ahima, R., Dinges, D., Sharma, V., Cummings, D.Neuroendocrine Profiles
    Associated with Energy Intake, Sleep, and Stress in the Night Eating Syndrome. (2005) J
    Clin Endocrinology & Metabolism. 05-1018
   Rosenhagen, M., Uhr, M., Schussler, P., Steiger, A. Elevated Plasma Ghrelin Levels in
    Night-Eating Syndrome. Am J Physiol Endocrinol Metab (2003); 284:E407-E415
   Striegel, R., Thompson, D., Franko, D., Barton, B., Affenito, S., Daniels, S. Definitions of
    Night Eating in Adolescent Girls (2004) Obes Res; 12:1311-1321
   O’Reardon, J., Stunkard, A., Allison K. Clinical Trial of Sertaline in the Treatment of Night
    Eating Syndrome (2004) Int J Eat Disord 35: 16-26