MEBO on Treating Traumatic Keratitis

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                        The Chinese Journal of Burns Wounds and Surface Ulcers1997, (2) 45

                 MEBO for Treating Traumatic Keratitis
                    Chun-Lian Liu Qing-Min Zeng Hui-Qin Guo
         Peoples’ Hospital of Xia-Jiang County, Jiang-Xi Province (331400)

[Abstract] Report admitted 31 cases of traumatic keratitis since 1992, all of the
applied MEBO in treatment. Method is applied on conjunctiva sac. Results: All
cured with short healing time. Editor considers there are no toxic side effects to
ocular tissue and have obvious effect in prophylaxis, alleviating tissue dystrophy,
enhancing lesion healing, and shortening the process, which is another ideal method
to treat traumatic keratitis.
[Key Words] conjunctiva sac cornea trauma

Corneal trauma is more often at primary hospital, yet leaves lots sequela after
treatment, such as achlys or keratoleukoma, that influent vision. Since 1992, the
author applied the MEBO to treat patients of traumatic keratitis, lesion heals fast
without keratoleukoma, elevated vision and the prognosis is remarkable. The
reports are as followed:

General Information:

Admit 31 cases of traumatic keratitis from out-patient department by random, 20
males, 11 females, age from 2 to 56 years old, course of disease from 2 hours to 3
days, and consists of 19 cases abraded by the rice stick , the tree branches, etc., 12
cases of foreign body injury, such as explosion, the Chinese chestnut monkey, the
iron chips, etc., and the foreign body is either stay on the surface of cornea or
penetrate into stroma, yet without penetration through anterior chamber under the
examination of slit lamp microscope. The injured eyes all have stabbing pains,
photophobia, tears and foreign body irritation. Vision exam ranges from 0.1-0.6,
cornea surface abrasion, foreign bodies stuck or penetrate into stroma, topical
spot-like or laminated white opaque, peripheral transparent cornea, and fluorescein
dying test positive, no special changes are seen on anterior chamber.


One percent lidocaine surface anesthesia on conjunctiva sac three times with 3
minutes interval for those who had foreign body retained, and lift foreign body by
corneal foreign body spade or 6.5# needles, dilate pupil once by 1% atropine. Then
applied MEBO on conjunctiva sac every 1 to 2 hours, and reduce gradually time of
applying the drug when the symptoms relieve. Follow up every other day.

Typical Cases:

Case 1 Female, 39 years old, farmer, suburb residents, because of trauma (the rice
stick) on the left for 4 days, complied with stabbing pains, photophobia, tears, vision
blur. Inspection: Left vision 0.1, no eyelid laceration, some congestion on palpebral
conjunctiva, bulbar conjunctiva fundamental mixed congestion(#), some purulent

                         The Chinese Journal of Burns Wounds and Surface Ulcers1997, (2) 45

secretion on conjunctiva sac, transverse perforation on the central cornea without
foreign body retained, topical white haze, slightly hollow, peripheral cornea
transparent, not seeing KP on the anterior chamber, small pupil, sensitive to light
reflex, fundus not examined. Pupil dilation immediately, applied MEBO on the
conjunctiva sac, foreign body irritation vanished, apparent pain relief around 2 to 3
minutes later. Instruct patient to apply the drug every 1 to 2 hours. Followed up in
the third day and found slight bulbar conjunctiva congestion, corneal lesion with mild
haze, patient informed topical symptoms vanished 5 days later, clear vision, and
exam found fleet-like haze, followed up 7 days later and found no conjunctiva
congestion, transparent cornea, fluorescein dying test negative, vision 1.0.
Case 2 Male,28 years old, welder, visit the clinics because of left eye foreign body
irritation, pain, photophobia, tears for 1 hour. Complaint sparks got into the eye
during welding an hour ago, at that time, blunt pain on the left eye and foreign body
irritation and so on, then visit the hospital. Inspection found a dark brown foreign
body retained on the surface of the left central cornea. Immediately bulbar
conjunctiva surface anesthesia three times by 1% lidocaine and lift the foreign body
with foreign body spade, applied MEBO, followed up 2 days later and found
transparent cornea, healed lesion, vision as usual, recovered.


All 31 cases were recovered. Criteria for recovery: healed lesion, only fleet-like haze
or nothing on the cornea, fluorescein dying test negative. Minimum 3 days and
maximum 9 days of treatment course.


The author once used antibiotics topical or general to treat traumatic keratitis patients,
though most recovered through the treatment, yet reached almost 1 moth in longer
treatment course, with higher morbidity of complications, such as achly,
keratoleukoma, etc., and badly affect the vision. Xu’s moist burn ointment extract
from edible vegetable oil, bee wax and Chinese medicines, the main ingredients are
β-Sitosterol et al. Treat by Xu’s moist burn ointment which characters are
intoxication, non-irritation, well infinity with the lesion, analgesic, prophylaxis, and can
eliminate dystrophy, enhance microcirculation, improve healing without scars. It is
another ideal therapy to traumatic keratitis.