Victorian Cancer Trials Link and finding suitable clinical trials for adolescents and young adults In 2007 and 2008, the Victorian Cancer Agency funded the Cancer Council Victoria to develop a clinical trial matching database to make it easier for cancer patients and clinicians to find suitable clinical trials. The Victorian Cancer Trials Link (VCTL) website was initiated by Professor Raymond Snyder and the Victorian Cooperative Oncology Group Breast Cancer Committee for breast cancer trials and was then further expanded to include all tumour streams including Paediatric and Adolescent and Young Adult (AYA) cancers. Improvements in cancer survival rates for AYA lag behind those in children and older patients over the last 3 decades. Clinical trials provide research traction that can improve survival outcomes. AYA oncology patients suffer from a diverse range of tumours and are treated across paediatric and adult health care sectors, with poor clinical trials recruitment. Improving access to clinical trials for AYA patients is one of the key challenges in optimizing the management of AYA. The Victorian Cancer Trials Link (VCTL) website is a clinical trial matching database to make it easier for cancer patients and clinicians to find suitable clinical trials for AYA cancer patients. It includes all tumour streams including Paediatric and Adolescent and Young Adult cancers. AYA patients can input their age to find a clinical trial suitable for them if one is available. VCTL searches can also be performed by keyword or hospital. It is important to note that the VCTL is not a clinical trial registry; it is a trial matching database that links patients or clinicians to the relevant clinical trial registry for more comprehensive information via a hyperlink. Hospital contact details, including a name and phone number, are displayed for all Victorian sites participating in each trial and this is a distinguishing feature. A Victorian AYA clinical trial recruitment rate is currently being estimated by the Victorian & Tasmanian Youth Cancer Network (VTYCN). Once known, this will provide a baseline on which to measure change over time. Anne Mitchell et al reported an AYA recruitment rate of approximately 5% (21/409) for the years 1992 to 1996 for sarcoma, brain, haematological and germ cell cancers investigated. A VTYCN aim is to improve the baseline AYA rate in line with the VCAP target. The average clinical trial recruitment rate for all cancers in Victoria is approximately 7% based on Victorian Cancer Registry incidence data. The VCTL is a unique resource for Victoria that has the potential to build real capacity in the area of clinical trials recruitment, for all patient age groups. For further VCTL information, visit the website at www.cancervic.org.au/trials or contact Cancer Council Victoria by email at firstname.lastname@example.org For further Victorian & Tasmanian Youth Cancer Network or AYA clinical trial information, contact – YouthCancerProject@petermac.org or 03 9656 5241. References: 1. Victorian Cancer Trials Link – www.cancervic.org.au/trials 2. Clinical Trials Office, Cancer Council Victoria. Report on 2009 Clinical Trial Activity in Victoria. Melbourne: Cancer Council Victoria, September 2010. http://www.cancervic.org.au/downloads/VCTL/CTMS_2009_- _Review_report_Final_.pdf 3. Mitchell AE, Scarcella DL, Rigutto GL, Thursfield VJ, Giles GG, Sexton M et al. Cancer in adolescents and young adults: treatment and outcome in Victoria. Med J Aust 2004; 180:59-62.