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ORIGINAL ARTICLES/Heikki Huikuri

1.    Huikuri HV, Ikäheimo MJ, Linnaluoto MK, Takkunen JT. Left ventricular response to
      isometric exercise and its value in predicting the change in ventricular function after mitral
      valve replacement for mitral regurgitation. Am J Cardiol 1983, 51: 1110-1115.

2.    Huikuri HV. Effect of mitral valve replacement on left ventricular function in mitral
      regurgitation. Br Heart J 1983, 49: 328-333.

3.    Huikuri HV, Ikäheimo MJ, Takkunen JT. Left ventricular response to isometric exercise in
      aortic valve diseases and its value in the optimal timing of aortic valve replacement. Acta
      Med Scand 1983, 213: 399-404.

4.    Huikuri HV, Ikäheimo MJ, Linnaluoto MK, Takkunen JT. Value of isometric exercise
      testing in the optimal timing of aortic valve replacement in aortic regurgitation. Eur Heart J
      1983, 4: 632-638.

5.    Huikuri HV, Takkunen JT. Value of isometric exercise testing during cardiac catheterization
      in patients with mitral valve stenosis. Am J Cardiol 1983, 52: 540-543.

6.    Huikuri HV. Isometric exercise testing in patients with valvular heart disease. Acta Univ.
      Ouluensis, series D 105, 1983. (Doctoral Thesis).

7.    Lilja M, Huikuri H, Jounela A, Juustila HJ, Paalzov G. Clonidine twice daily in
      hypertension. Acta Med Scand 1983, 214: 111-117.

8.    Jounela AJ, Honkala M, Huikuri H. Antihypertensive effects of prizidilol. Ann Clin Res
      1984, 16: 176-180.

9.    Huikuri HV, Korhonen UR, Linnaluoto MKL, Takkunen JT. Effect of coronary artery
      bypass grafting on left ventricular response to isometric exercise. Am J Cardiol 1984, 54:
      514-518.

10.   Pentikäinen PJ, Huikuri H, Jounela AJ, Wilen G. Disopyramide pharmacokinetics in patients
      with acute myocardial infarction. Eur J Clin Pharmacol 1985, 28: 45-51.

11.   Huikuri HV, Korhonen UR, Takkunen JT. Ventricular arrhythmias induced by dynamic and
      static exercise in relation to coronary artery bypass grafting. Am J Cardiol 1985, 55: 948-951.

12.   Huikuri HV, Korhonen UR, Heikkilä J, Takkunen JT. Detection of coronary artery disease
      by thallium scintigraphy in patients with valvular heart disease. Br Heart J 1986, 56: 146-151.

13.   Huikuri HV, Airaksinen KEJ, Lilja M, Takkunen JT. Echocardiographic evaluation of left
      ventricular response to isometric exercise in young insulin-dependent diabetics. Acta Diab
      Lat. 1986, 13: 193-200.

14.   Huikuri HV, Korhonen UR, Linnaluoto MK, Takkunen JT. The relationship of ventricular
      arrhythmias to the angiographically and scintigraphically estimated extent of ventricular
      damage late after myocardial infarction. Clin Cardiol 1987, 10: 175-179.
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15.   Huikuri HV, Korhonen UR, Ikäheimo MJ, Heikkilä J, Takkunen JT. Detection of coronary
      artery disease by thallium imaging using a combined intravenous dipyridamole and isometric
      handgrip test in patients with aortic valve stenosis. Am J Cardiol 1987, 59: 336-340.

16.   Huikuri HV, Ikäheimo MJ, Korhonen UR, Heikkilä J, Takkunen JT. Thallium scintigraphy
      in prediction of occlusion of bypass grafts in asymptomatic and symptomatic patients. Acta
      Med Scand 1987, 222: 311-318.

17.   Airaksinen KEJ, Ikäheimo MJ, Linnaluoto MK, Huikuri HV, Takkunen JT. Increased left
      atrial size relative to left ventricular size in young women with insulin dependent diabetes.
      Diab Res 1987, 6: 37-41.

18.   Groundstroem KW, Huikuri HV, Korhonen UR, Ikäheimo MJ, Heikkilä J, Takkunen JT.
      Comparison of echocardiographic and radionuclide methods with contrast angiography
      assessment of left ventricular function- response to isometric exercise in subjects without
      definite heart disease. Ann Clin Res 1987, 19: 187-194.

19.   Huikuri HV, Korhonen UR, Ikäheimo MJ, Airaksinen KEJ, Heikkilä J, Takkunen JT.
      Comparison of dipyridamole-handgrip test and bicycle exercise test for thallium tomographic
      imaging. Am J Cardiol 1988, 61: 264-268.

20.   Huikuri HV, Ikäheimo MJ, Airaksinen KEJ, Linnaluoto MK, Heikkilä J, Takkunen JT.
      Prevalence and significance of gallium- 67 uptake of the heart after open-heart surgery. Am J
      Cardiol 1988, 61: 405-408.

21.   Ikäheimo MJ, Huikuri HV, Airaksinen KEJ, Korhonen UR, Linnaluoto MK, Tarkka M,
      Takkunen JT. Pericardial effusion after cardiac surgery: Incidence, relation to the type of
      surgery, antithrombotic therapy, and early coronary bypass graft patency. Am Heart J 1988,
      116: 97-102.

22.   Kimura S, Basset AL, Cameron JS, Huikuri H, Kozlovskis PL, Myerburg RJ. Cellular
      electrophysiological changes during ischemia in isolated coronary-perfused cat ventricle with
      healed myocardial infarction. Circulation 1988, 78: 401-406.

23.   Huikuri HV, Airaksinen KEJ, Ikheimo MJ, Korhonen UR, Heikkilä J, Takkunen JT.
      Detection of coronary artery disease by dipyridamole thallium tomography in mitral valve
      stenosis. Am J Cardiol 1989, 70: 230-233.

24.   Groundstroem KWE, Huikuri HV, Ikäheimo MJ, Korhonen UR, Linnaluoto MK, Takkunen
      JT. Echocardiographic assessment of left ventricular function during isometric exercise in
      aortic valve incompetence. Am J Noninv Cardiol 1989, 3: 342-344.

25.   Groundstroem KWE, Huikuri H, Korhonen UR, Ikäheimo M, Heikkilä J, Torniainen P,
      Linnaluoto M, Takkunen J. Left ventricular dimensions during isometric exercise in aortic
      valve incompetence assessed by M-mode echocardiography and gated equilibrium
      radionuclide angiography. Eur J Nucl Med 1989, 15: 204-209.

26.   Huikuri HV, Zaman L, Castellanos A, Kessler KM, Cox M, Glicksman F, Myerburg RJ.
      Changes in spontaneous sinus node rate as an estimate of cardiac autonomic tone during
      stable and unstable ventricular tachycardia. J Am Coll Cardiol 1989, 13: 646-652.
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27.   Ikäheimo MJ, Ruskoaho HJ, Airaksinen KEJ, Huikuri HV, Korhonen UR, Leppäluoto PJ,
      Tuominen MO, Takkunen JT. Plasma levels of atrial natriuretic peptide during myocardial
      ischemia induced by percutaneous transluminal angioplasty or dynamic exercise. Am Heart J
      1989, 117: 837-841.

28.   Poukkula A, Korhonen UR, Huikuri H, Linnaluoto MK. Theophylline and salbutamol in
      patients with severe obstructive pulmonary disease and concurrent heart disease: Effect on
      cardiac arrhythmia. J Int Med 1989, 226: 229-234.

29.   Myerburg RJ, Kessler KM, Cox M, Glicksman F, Interian A, Huikuri H, Fernandez P,
      Castellanos A. Reversal of proarrhythmic effects of flecainide acetate and encainide
      hydrochloride by propranolol. Circulation 1989, 80: 1571-1579.

30.   Airaksinen KEJ, Koistinen J, Ikäheimo MJ, Huikuri HV, Korhonen UR, Pirttiaho H,
      Linnaluoto MK, Takkunen JT. Augmentation of atrial contribution to left ventricular filling in
      IDDM subjects as assessed by Doppler echocardiography. Diabetes Care 1989, 12: 159-161.

31.   Huikuri HV, Cox M, Interian A, Castellanos A, Myerburg RJ. Efficacy of intravenous
      propranolol for suppression of inducibility of ventricular tachyarrhythmias with different
      electrophysiological characteristics in coronary artery disease. Am J Cardiol 1989, 64: 1305-
      1309.

32.   Castellanos A, Fuenmayor AJ, Huikuri H, Interian Jr. A, Cox M, Myerburg RJ. Dynamics of
      atrioventricular nodal conduction ratios of alternating Wenckebach periods. Am J Cardiol
      1989, 64: 1047-1049.

33.   Airaksinen KEJ, Ikäheimo MJ, Huikuri HV, Koistinen MJ, Linnaluoto MK, Takkunen JT.
      Effects of isometric exercise and heart rate on left ventricular filling pattern assessed by
      pulsed Doppler echocardiography. J Int Med 1989, 226: 245-249.

34.   Airaksinen KEJ, Koistinen MJ, Ikäheimo MJ, Pirttiaho H, Huikuri HV, Takkunen JT. Effect
      of coronary artery disease on parasympathetic cardiovascular reflexes in NIDDM patients.
      Diab Care 1990, 13: 83-86.

35.   Groundstroem K, Huikuri H, Korhonen U, Ikäheimo M, Heikkilä J, Torniainen P, Linnaluoto
      M, Takkunen J. Isometric exercise testing and echocardiography at rest in aortic valve
      incompetence. Nucl Med Communic 1990, 11: 279-287.

36.   Koistinen J, Huikuri HV, Korhonen UR, Linnaluoto MK, Takkunen JT. Evaluation of
      exercise electrocardiography and thallium tomographic imaging in detecting asymptomatic
      coronary arterydisease in diabetic subjects. Br Heart J 1990, 63: 7-11.

37.   Huikuri HV, Yli-Mäyry S, Korhonen UR, Airaksinen KEJ, Ikäheimo MJ, Linnaluoto MK,
      Takkunen JT. Prevalence and prognostic significance of complex ventricular arrhythmias
      after coronary arterial bypass graft surgery. Int J Cardiol 1990, 27: 333-337.

38.   Koistinen MJ, Huikuri HV, Pirttiaho H, Linnaluoto MK, Takkunen JT. Evaluation of 24-
      hour ambulatory electrocardiographic recording in detecting asymptomatic coronary artery
      disease in diabetic subjects. Am J Noninv Cardiol 1990, 4: 312-316.
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39.   Huikuri HV, Kessler KM, Terracall L, Castellanos A, Linnaluoto MK, Myerburg RJ.
      Reproducibility and circadian rhythm of heart rate variability in healthy subjects. Am J
      Cardiol 1990, 65: 391-93.

40.   Yli-Mäyry S, Huikuri HV, Korhonen UR, Airaksinen KEJ, Ikäheimo MJ, Linnaluoto MK,
      Takkunen JT. Prevalence and prognostic significance of exercise induced ventricular
      arrhythmias after coronary artery bypass grafting. Am J Cardiol 1990, 66: 1451-1454.

41.   Peuhkurinen K, Ikäheimo M, Airaksinen J, Huikuri H, Linnaluoto M, Takkunen J. Changes
      in myocardial energy metabolism in elective coronary angioplasty. Cardiovasc Res 1991, 25:
      158-163.

42.   Airaksinen KEJ, Niemelä M, Ikäheimo MJ, Huikuri HV, Linnaluoto MK, Takkunen JT.
      Effects of coronary arterial occlusion on vagal control of heart rate. Int J Cardiol 1991, 30:
      269-274.

43.   Kettunen R, Huikuri HV, Heikkilä J, Takkunen JT. Usefulness of Technetiumc-99m-MIBI
      and thallium-201 in tomographic imaging combined with high-dose dipyridamole and
      handgrip exercise for detecting coronary artery disease. Am J Cardiol 199l, 68: 575-579.

44.   Huikuri HV, Yli-Mäyry S, Airaksinen KEJ, Ikäheimo MK, Linnaluoto MK, Takkunen JT.
      Clinical and angiographic prediction of cardiac death after coronary artery bypass surgery. Br
      Heart J 1992; 67: 216-220.

45.   Huikuri HV, Peuhkurinen KJ, Takkunen JT. Relationship between beat-to-beat changes in
      hemodynamic state and action potential duration during rapid ventricular rhythm in man.
      PACE 1992; 15: 878-884.

46.   Huikuri HV, Linnaluoto MK, Seppänen T, Airaksinen KEJ, Kessler KM, Myerburg RJ.
      Circadian rhythm of heart rate variability in survivors of cardiac arrest. Am J Cardiol 1992,
      70: 610-15.

47.   Peuhkurinen KJ, Huikuri HV, Takkunen JT. Blood pressure, atrial natriuretic peptide and
      catecholamines during rapid ventricular pacing and effects of beta-adrenergic blockade in
      coronary artery disease. Am J Cardiol 1992, 69: 35-39.

48.   Valkama JO, Huikuri HV, Linnaluoto MK, Takkunen JT. Circadian rhythm of ventricular
      tachycardia in patients with coronary artery disease. Int J Cardiol 1992, 34: 173-178.

49.   Kettunen R, Huikuri HV, Heikkilä J, Takkunen JT. Preoperative diagnosis of coronary artery
      disease in patients with valvular heart disease using Technetium-99m isonitrile tomographic
      imaging together with high-dose dipyridamole and handgrip exercise. Am J Cardiol 1992; 69:
      1442-1445.

50.   Huikuri HV, Koistinen MJ, Takkunen JT. Efficacy of intravenous sotalol for suppressing
      inducibility of supraventricular tachycardias at rest and during isometric exercise. Am J
      Cardiol 1992, 69: 498-502.
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51.   Yli-Mäyry S, Huikuri HV, Korhonen UR, Airaksinen KEJ, Ikäheimo MJ, Linnaluoto MK,
      Takkunen JT. Efficacy and safety of anticoagulant therapy started pre-operatively in
      preventing coronary vein graft occlusion. Eur Heart J 1992; 13: 1259-1264.

52.   Yli-Mäyry S, Huikuri HV, Airaksinen KEJ, Ikäheimo MJ, Linnaluoto MK, Takkunen JT.
      Usefulness of postoperative exercise test for predicting cardiac events after coronary artery
      bypass grafting. Am J Cardiol 1992; 70: 56-59.

53.   Koistinen MJ, Airaksinen KEJ, Huikuri HV, Pirttiaho H, Linnaluoto MK, Ikäheimo MJ,
      Takkunen JT. Asymptomatic coronary artery disease in diabetes: associated with autonomic
      neuropathy? Acta Diabetol 1992; 28: 199-202.

54.   Huikuri HV, Yli-Mäyry S. Frequency-dependent effects of d-sotalol and amiodaone on the
      action potential duration of the human right ventricle. PACE 1992, 15: 2103-2107.

55.   Valkama JO, Huikuri HV, Airaksinen KEJ, Linnaluoto MK, Takkunen JT. Changes in
      frequency domain measures of heart rate variability in relation to the onset of ventricular
      tachycardia in acute myocardial infarction. Int J Cardiol 1993;38: 177-182.

56.   Huikuri HV, Valkama JO, Airaksinen KEJ, Seppänen T, Kessler KM, Takkunen JT, and
      Myerburg RJ. Frequency domain measures of heart rate variability before the onset of
      nonsustained and sustained ventricular tachycardia in patients with coronary artery disease.
      Circulation 1993; 87: 1220-1228.

57.   Chakko S, Mulingtapang RF, Huikuri HV, Kessler KM, Materson BJ, Myerburg RJ.
      Alterations in heart rate variability and its circadian rhythm in hypertensive patients with left
      ventricular hypertrophy free of coronary artery disease. Am Heart J 1993; 126: 1364-1372.

58.   Yli-Mäyry S, Huikuri HV. Clinical and angiographic prediction of myocardial infarction and
      recurrence of severe angina during a five-year follow-up after coronary artery bypass grafting.
      Am J Cadiol 1993; 72: 1371-1375.

59.   Uusimaa PA, Ikäheimo MJ, Ruskoaho H, Airaksinen KEJ, Huikuri HV, Linnaluoto MK,
      Takkunen JT, Peuhkurinen KJ. Release of atrial natriuretic peptide in relation to metabolic
      changes during myocardial ischaemia induced by coronary angiolplasty. Eur Heart J 1993; 14:
      682-686.

60.   Airaksinen KEJ, Ikäheimo MJ, Huikuri HV, Linnaluoto MK, Takkunen JT. Responses of
      heart rate variability to coronary occlusion during angioplasty. Am J Cardiol 1993; 72: 1026-
      30.

61.   Airaksinen KEJ, Hartikainen JEK, Niemelä MJ, Huikuri HV, Mussalo HM, Tahvanainen
      KUO. Valsalva manoeuvre in the assessment of baroreflex sensitivity in patients with
      coronary artery disease. Eur Heart J 1993; 14: 1519-1523.

62.   Huikuri HV, Niemelä MJ, Ojala S, Rantala A, Ikäheimo MJ, Airaksinen KEJ. Circadian
      rhythms of frequency domain measures of heart rate variability in healthy subjects and
      patients with coronary artery disease. Effects of arousal and upright posture. Circulation 1994;
      90: 121-126.
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63.   Niemelä MJ, Airaksinen KEJ, Huikuri HV. Effect of beta-blockade on heart rate variability
      in patients with coronary artery disease. J Am Coll Cardiol 1994; 23 (6): 1370-1377.

64.   Peuhkurinen KEJ, Huikuri HV, Linnaluoto MK, Takkunen JT. Changes in myocardial
      metabolism and transcardiac electrolytes during simulated ventricular tachycardia: Effects of
      beta-adrenergic blockade. Am Heart J 1994; 128: 96-105.

65.   Valkama JO, Huikuri HV, Airaksinen KEJ, Linnaluoto MK, Takkunen JT. Determinants of
      frequency domain measures of heart rate variability in the acute and convalescent phases of
      myocardial infarction. Cardiovascular Res 1994; 28: 1273-1276.

66.   Airaksinen KEJ, Ikäheimo MJ, Peuhkurinen KJ, Yli-Mäyry S, Linnaluoto MK, Serka T,
      Huikuri HV. Effect of preocclusion stenosis severity on heart rate reactions to coronary
      occlusion. Am J Cardiol 1994; 74: 864 - 868.

67.   Airaksinen KEJ, Niemelä MJ, Huikuri HV. Effect of beta-blockade on baroflex sensitivity
      and cardiovascular autonomic function tests in patients with coronary artery disease. Eur
      Heart J 1994; 15: 1482-1485.

68.   Koistinen MJ, Huikuri HV, Pirttiaho H, Korhonen UR, Linnaluoto MK, Kuusi T, Takkunen
      JT, Taskinen MR. Asymptomatic coronary artery disease in diabetes: Relation to common
      risk factors, lipoproteins, apoproteins, and Apo E polymorphism. Acta Diabetol 1994; 31:
      210-214.

69.   Valkama JO, Huikuri HV, Koistinen MJ, Yli-Mäyry S, Airaksinen KEJ, Myerburg RJ.
      Relation between heart rate variability and spontaneous and induced ventricular arrhythmias
      in patients with coronary artery disease. J Am Coll Cardiol 1995; 25: 437-443.

70.   Airaksinen KEJ, Ylitalo KV, Peuhkurinen KJ, Ikäheimo MJ, Huikuri HV. Heart rate
      variability during repeated arterial occlusion in coronary angioplasty. Am J Cardiol 1995; 75:
      877 - 881.

71.   Huikuri HV, Koistinen MJ, Yli-Mäyry S, Airaksinen KEJ, Seppänen T, Ikäheimo MJ,
      Myerburg RJ. Impaired low frequency oscillations of heart rate in patients with prior acute
      myocardial infarction and life-threatening arrhythmias. Am J Cardiol 1995; 76: 56 - 60.

72.   Peuhkurinen KJ, Uusimaa PA, Ruskoaho H, Linnaluoto M, Huikuri H. Hemodynamic
      recovery, and catecholamines during simultaed ventricular tachycardia. PACE: 1995; 18:75-
      82.

73.   Huikuri HV, Yli-Mäyry S, Linnaluoto M, Ikäheimo MJ. Diurnal fluctuations in human
      ventricular and atrial refractoriness. PACE 1995; 18: 1362 - 1368.

74.   Airaksinen KEJ, Ikäheimo MJ, Huikuri HV. Stenosis severity and the occurrence of
      ventricular ectopic activity during acute coronary occlusion during balloon angioplasty. Am J
      Cardiol 1995; 76: 346 - 349.

75.   Perkiömäki J, Koistinen MJ, Yli-Mäyry S, Huikuri HV. Dispersion of the QT interval in
      patients with and without susceptibility to ventricular tachyarrhythmias after previous
      myocardial infacrtion. J Am Coll Cardiol 1995; 26: 174 - 179.
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76.   Koistinen MJ, Perkiömäki J, Airaksinen KEJ, Yli-Mäyry S, Ikäheimo MJ, Huikuri HV.
      Effects of perfusion of the infarct-related artery on risk markers of life-threatening
      arrhythmias in patients with prior myocardial infarction. Reblampa 1995; 8: 205 - 208.

77.   Huikuri HV, Koistinen MJ, Airaksinen KEJ, Ikäheimo MJ. Significance of perfusion of the
      infarct-related coronary artery for susceptibility to ventricular tachyarrhythmias in patients
      with prior myocardial infarction. Heart, 1996; 75:17-22.

78.   Airaksinen KEJ, Ikäheimo MJ, Niemelä MJ, Valkama JO, Peuhkurinen KJ, Huikuri HV.
      Effect of beta-blockade on heart rate variability during vessel occlusion at the time of
      coronary angioplasty. Am J Cardiol, 1996; 77:20-24.

79.   Koistinen MJ, Airaksinen KEJ, Huikuri HV, Linnaluoto MK, Heikkilä J, Torniainen P,
      Ahonen A. No difference in cardiac innervation of diabetic patients with painful and
      asymptomatic coronary artery disease. Diabetes Care, 1996, 19: 231-236.

80.   Huikuri HV, Seppänen T, Koistinen MJ, Airaksinen KEJ, Ikäheimo MJ, Castellanos A,
      Myerburg RJ. Abnormalities in beat-to-beat dynamics of heart rate before the spontaneous
      onset of life-threatening ventricular tachyarrhythmias in patients with prior myocardial
      infarction. Circulation 1996, 93: 1836-1844.

81.   Tulppo MP, Mäkikallio TH, Takala TES, Seppänen T, Huikuri HV. Quantitative beat-to-beat
      analysis of heart rate dynamics during exercise. Am J Physiol, 1996: 271: H244-H252

82.   Perkiömäki JS, Ikäheimo MJ, Pikkujämsä MS, Rantala AO, Lilja M, Kesäniemi YA, Huikuri
      HV. Dispersion of the QT interval and autonomic modulation of heart rate in hypertensive
      men with and without left ventricular hypertrophy. Hypertension, 1996; 28: 16-21

83.   Huikuri HV, Pikkujämsä SM, Airaksinen KEJ, Ikäheimo MJ, Rantala AO, Kauma H, Lilja
      M, Kesäniemi YA. Sex-related differences in autonomic modulation of heart rate in middle-
      aged subjects. Circulation, 1996, 94: 122-125.

84.   Huikuri HV, Ylitalo A, Pikkujämsä SM, Ikäheimo MJ, Airaksinen KEJ, Rantala AO, Lilja
      M, Kesäniemi YA. Heart rate variability in systemic hypertension. Am J Cardiol, 1996, 77:
      1073-1077

85.   Mäkikallio TH, Seppänen T, Niemelä M, Airaksinen KEJ, Tulppo M, Huikuri HV.
      Abnormalities in beat-to-beat complexity of heart rate dynamics in patients with a previuos
      myocardial infarction. J Am Coll Cardiol, 1996, 28: 1005-1011

86.   Korpelainen JT, Sotaniemi KA, Huikuri HV, Myllylä VV. Abnormal heart rate variability as
      a manifestation of autonomic dysfunction in hemispheric brain infarction. Stroke, 1996, 27:
      2059-2063

87.   Pikkuämsä SM, Huikuri HV, Ikäheimo MJ, Airaksinen KEJ, Rantala AO, Lilja M,
      Savolainen MJ, Reunanen A, Kesäniemi YA. Relationship between heart rate variability and
      cardiovascular risk factors in middle-aged males A.N.E. 1996; 1:354-362
                                                                                                  8

88.   Korpelainen JT, Huikuri HV, Sotaniemi KA, Myllylä VV. Abnormal heart rate variability
      reflecting autonomic dysfunction in brainstem infarction. Acta Neurol Scand 1996, 94: 337-
      342

89.   Huikuri HV, Airaksinen KEJ, Koistinen MJ, Palmgren J-E, Linnaluoto MK, Tikkanen P,
      Sellin L. Two-dimensional vector analysis of beat-to-beat dynamics of ventricular
      repolarization. A.N.E., 1997, 2(2):121-125.

90.   Airaksinen KEJ, Tahvanainen KUO, Kuusela TA, Huikuri HV, Niemelä MJ, Karjalainen P,
      Eckberg DL. Cross spectral analysis in assessment of baroreflex gain in patients with
      coronary artery disease. A.N.E, 1997, 2(3): 229-235.

91.   Airaksinen KEJ, Huikuri HV. Antiarrhythmic effect of repeated coronary occlusion during
      balloon angioplasty. J Am Coll Cardiol, 1997, 29: 1035-1038.

92.   Ekholm E.M.K., Hartiala J., Huikuri HV. Circadian rhythm of frequency-domain measures
      of heart rate variability in pregnancy. Br J Obstet Gynaecol, 1997, 104: 825-828.

93.   Mäkikallio TH, Seppänen T, Airaksinen KEJ, , Koistinen J, Tulppo M, Peng CK, Goldberg
      AL, Huikuri HV. Dynamic analysis of heart rate may predict subsequent ventricular
      tachycardia after myocardial infarction. Am J Cardiol, 1997, 80:779-783.

94.   Korpelainen JT, Sotaniemi KA, Huikuri HV, Myllylä VV. Circadian rhythm of heart rate
      variability is reversibly abolished in ischemic stroke. Stroke 1997; 28:2150-2154.

95.   Ylitalo A, Airaksinen KEJ, Tahvanainen KUO, Kuusela TA, Ikäheimo MJ, Rantala A, Lilja
      M, Huikuri HV. Baroreflex sensitivity in drug-treated systemic hypertension. Am J Cardiol,
      1997;80:1369-1372.

96.   Perkkiömäki JS, Huikuri HV, Koistinen JM, Mäkikallio TH, Castellanos A, Myerburg RJ.
      Heart rate variability and dispersion of QT interval in patients with vulnerability to ventricular
      tachycardia and ventricular fibrillation after previous myocardial infarction. J Am Coll
      Cardiol, 1997, 1997; 30: 1331-1338.

97.   Mäkikallio TH., Ristimäki T, Airaksinen KEJ, Peng C-K, Goldberg AL., Huikuri HV.. Heart
      rate dynamics in patients with stable angina pectoris and utility of fractal and complexity
      measures. Am J Cardiol 1998;81:27-31.

98.   Tulppo MP., Mäkikallio TH., Seppänen T, Laukkanen RT., Huikuri HV.. Vagal modulation
      of heart rate during exercise: effects of age and physical fitness. Am. J. Physiol. 1998; 274
      (Heart Circ. Physiol. 43):H424-H429.

99.   Tulppo MP., Mäkikallio TH., Seppänen T, Airaksinen KEJ., Huikuri HV. Heart rate
      dynamics during accentuated sympathovagal interaction. Am. J. Physiol. 1998;274 (Heart
      Circ. Physiol.43):H810-H816.

100. Huikuri HV, Mäkikallio TH, Airaksinen KEJ, Seppänen T, Puukka P, Räihä I, Sourander L.
     Power-law relationship of heart rate variability and mortality in the elderly. Circulation,
     1998;97:2031-2036.
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101. Airaksinen KEJ, Ikäheimo MJ, Linnaluoto M, Tahvanainen KUO, Huikuri HV.Gender
     difference in autonomic and hemodynamic reactions to abrupt coronary occlusion. J Am Coll
     Cardiol 1998;31:301-6.

102. Pikkujämsä SM., Huikuri HV., Airaksinen KEJ, Rantala AO., Kauma H, Lilja M, Savolainen
     MJ., Kesäniemi YA. Heart rate variability and baroreflex sensitivity in hypertensive subjects
     with and without metabolic features of insulin resistance syndrome. Am J Hypert,
     1998;11:523-531.

103. Castellanos A, Moleiro F, Chakko S, Acosta H, Huikuri H, Mitrani R, Myerburg RJ. Heart
     rate variability in inappropriate sinus tachycardia. Am J Cardiol 1998; 81:531-532.

104. Airaksinen KEJ, Tahvanainen KUO, Eckberg DL., Niemelä MJ, Ylitalo A, Huikuri HV.
     Arterial baroreflex impairment in patients during acute coronary occlusion. J Am Coll Cardiol
     1998;32:1641-7.

105. Kuikka JT, Bendel S, Kettunen R, Hartikainen J, Remes J, Vanninen E, Yang J, Huikuri HV.
     Effect of revascularization on (99mTc) Sestamibi and (123I) IPPA uptakes in patients with
     myocardial infarction. Nuklearmedizin 1998; 37 (Suppl.): S12-14.

106. Ristimäki T, Huikuri HV, Teesalu R. Heart rate variability in patients with the first and
     recurrent myocardial infarction. Clin Auton Res 1998; 8(4): 195-9.

107. Tapanainen JM, Seppänen T, Laukkanen R, Loimaala A, Huikuri HV.. Significance of the
     accuracy of RR interval detection for the analysis of new dynamic measures of heart rate
     variability. Ann Noninvas Electrocard, A.N.E. 1999; 4(1): 10-18.

108. Extramiana F, Neyroud N, Huikuri HV, Koistinen MJ, Coumel P, Maison-Blanche P. QT
     interval and arrhythmic risk assessment after myocardial infarction. Am J Cardiol 1999;
     83:266-269.

109. Loimaala A, Sievanen H, Laukkanen R, Parkka J, Vuori I, Huikuri HV. Accuracy of a novel
     real-time microprocessor QRS detector for heart rate variability assessment. Clin Physiol
     1999;19(1):84-88.

110. Ylitalo A, Airaksinen KEJ, Sellin L, Huikuri HV. Effects of combination antihypertensive
     therapy on baroreflex sensitivity and heart rate variability in systemic hypertension. Am J
     Cardiol 1999; 83:885-889.

111. Mäkikallio TH, Høiber S, Køber L, Torp-Pedersen C, Peng C-K, Goldberger AL., Huikuri
     HV and the TRACE Investigators. Fractal analysis of heart rate dynamics as a predictor of
     mortality in patients with depressed left ventricular function after acute myocardial infarction.
     Am J Cardiol 1999; 83; 836-839.

112. Makikallio TH, Koistinen J, Jordaens L, Tulppo MP, Wood N, Glosarsky B, Peng CK,
     Goldberger AL, Huikuri HV. Heart rate dynamics before spontaneous onset of ventricular of
     ventricular fibrillation in patients with healed myocardial infarcts. Am J Cardiol 1999; 83(6):
     880-4.
                                                                                               10

113. Airaksinen KEJ, Ylitalo A, Niemelä MJ, Tahvanainen KUO, Huikuri HV. Heart rate
     variability and occurrence of ventricular arrhythmias during balloon occlusion of a major
     coronary occlusion. Am J Cardiol 1999; 83:1000-1005.

114. Tikkanen PE, Sellin LC, Kinnunen HO, Huikuri HV. Using simulated noise to define
     optimal QT intervals for computer analysis of amlulatory ECG. Medical Engineering
     &Physics 1999; 21; 15-25.

115. Poutiainen A-M, M. Koistinen J, Airaksinen KEJ, Hartikainen JEK., Kettunen RJ,
     Karjalainen JE, Huikuri HV. Prevalence and Natural Course of Ectopic Atrial Tachycardia.
     Eur Heart J 1999; 20(9): 694-700.

116. Huikuri HV, Jokinen V, Syvanne M, Nieminen MS, Airaksinen KEJ, Ikäheimo MJ,
     Koistinen MJ, Kauma H, Kesäniemi YA, Majahalme S, Niemela K, Frick H. Heart rate
     variability and progression of coronary atherosclerosis. Arteriosl Thromb Vasc Biol 1999;
     19:1979-1985.

117. Perkiömäki JS, Koistinen JM, Huikuri HV. Standard 12-lead and 24-hour ambulatory
     electrocardiographic abnormalities in survivors of tachyarrhythmic cardiac arrest. A.N.E.
     1999; 4(2): 158-166.

118. Tulppo MP, Mäkikallio TH, Laukkanen RJ, Huikuri HV. Differences in autonomic
     modulation of heart rate during arm and leg ecercise. Clin Physiol 1999; 19(4):294-9.

119. Pikkujämsä S, Mäkikallio T, Sourander LB, Räihä IJ, Puukka P, Skyttä J, Peng C-K,
     Goldberger AL, Huikuri HV. Cardiac interbeat interval dynamics from childhood to
     senescene: Comparison of conventional and new measures based on fractals and chaos theory.
     Circulation 1999; 100:393-399.

120. Korpelainen JT, Sotaniemi KA, Makikallio A, Huikuri HV, Myllyla VV. Dynamic behavior
     of heart rate in ischemic stroke. Stroke 1999; 30(5): 1008-13.

121. Mitrani RD, Kloosterman EM, Huikuri H, Dylewski J, Atapattu S, Interian A Jr, Castellanos
     A, Myerburg RJ. Muscarinic receptor stimulation with edrophonium hydrochloride does not
     elevate ventricular fibrillation thresholds in humans. J Cardiovasc Electrophysiol 1999; 10(6):
     809-16.

122. Bloch Thomsen PE, Huikuri H, Køber L, Linde C, Koistinen J, Ohm O-J, Rokkedal J, Torp-
     Pedersen C. Lessons from the Nordic ICD pilot study. Lancet 1999; 353(19): 2130.

123. Vikman S, Mäkikallio TH, Yli-Mäyry S, Pikkujämsä S, Koivisto A-M, Reinikainen P,
     Airaksinen KEJ, Huikuri HV. Altered complexity and correlation properties of R-R interval
     dynamics before the spontaneous onset of paroxysmal atrial fibrillation. Circulation 1999;
     100:2079-2084.

124. Huikuri HV, Poutiainen A-M, Mäkikallio TH, Koistinen JM, Airaksinen KEJ, Mitrani R,
     Myerburg RJ, Gastellanos A. Dynamic behavior and autonomic nervous regulation of ectopic
     atrial tachycardia. Circulation 1999; 100:1416-1422.
                                                                                                 11

125. Bendel S, Kettunen R, Hartikainen J, Remes J, Vanninen E, Yang J, Kuikka J, Huikuri HV.
     Similar effect of revascularization on technetium-99m sestamibi and 15-(p-iodophenyl)
     pentadecanoic acid uptake in myocardial infarction patients. Eur J Nucl Med 1999; 26:1304-
     1309.

126. Ylitalo A, Airaksinen KEJ, Hautanen A, Kupari M, Carson M, Virolainen J, Savolainen M,
     Kauma H, Kesaniemi YA, White PC, Huikuri HV. Baroreflex sensitivity and the renin
     angiotensin system genes. J Am Coll Cardiol 2000; 35:194-200.

127. Huikuri HV, MäkikallioTH, Peng C-K, Goldberger AL, Hintze U, Møller M, and the
     Diamond Study Group Fractal correlation properties of R-R Interval dynamics and mortality
     in patients with depressed left ventricular function after an acute myocardial infarction.
     Circulation 2000; 101:47-53.

128. Laitio TT, Huikuri HV, Kentala ESH, Mäkikallio TH, Jalonen JR, HeleniusH, Sariola-
     Heinonen K, Yli-Mäyry S, Scheinin H. Correlation properties and comlexityof perioperative
     RR-interval dynamics in coronary artery bypass surgery patients. Anestesiology 2000; 93(1):
     69-80.

129. Ekholm EM, Salminen EK, Huikuri HV, Jalonen J, Antila KJ, Salm Rantanen VT.
     Impairment of heart rate variability during paclitaxel therapy. Cancer 2000; 88(9): 2149-2153.

130. Perkiömäki JS, Mäkikallio TH, Huikuri HV. Nonlinear analysis of heart rate variability:
     Fractal and complexity measures of heart rate behavior. A.N.E. 2000; 5(2): 179-187.

131. Niemelä RK, Pikkujämsä SM, Hakala M, Huikuri HV, Airaksinen KE. No signs of
     autonomic nervous system dysfunction in primary Sjorgen´s syndrome evaluated by 24 hour
     herat rate variability. J Rheumatol 2000; 27:2605-2610.

132. Loimaala A, Huikuri HV, Oja P, Pasanen M, Vuori I. Controlled 5-mo aerobic training
     improves heart rate but not heart rate variability or baroreflex sensitivity. J App Physiol 2000;
     89:1825-1829.

133. Castellanos A, Moleiro F, Lopera G, Huikuri HV, Interian A Jr., Myerburg RJ. Dynamics of
     the uncorrected QT interval during vagalinduced lengthening of RR intervals. Am J Cardiol
     2000; 86:1390-1392.

134. Saermark K, Moeller M, Hintze U, Moelgaard H, Bloch-Thomsen PE, Huikuri HV,
     Mäkikallio T, Levitan J, Lewkowicz M. Comparison of recent methods of analyzing heart rate
     variability. Fractals 2000; 8:315-322.

135. Lopera G, Huikuri HV, Mäkikallio TH, Castellanos A, Myerburg RJ. Muerte súbita
     isquémica: análisis crítico de los marcadores de riesgo. Rev Esp Cardiol 2000; 53:568-578.

136. Tulppo MP, Hughson RL, Mäkikallio TH, Airaksinen KEJ, Seppänen T, Huikuri HV.
     Effects of exercise and passive head-up tilt on fractal and complexity dynamics of heart rate
     dynamics. Am J Physiol 2001; 280:H1081-7.
                                                                                                 12

137. Pikkujämsä SM, Mäkikallio TH, Airaksinen KEJ, Huikuri HV. Determinants and
     interindividual variation of R-R interval dynamics in healthy middle-aged subjects. Am J
     Physiol 2001; 280:H1400-H1406.

138. Salo MA, Huikuri HV, Seppänen T. Dealing with ectopic beats in heart rate variability
     analysis: Effects of editing on time and frequency domain measures. A.N.E. 2001; 6:5-17.

139. Mäkikallio TH, Huikuri HV, Hintze U, Videbæk J, Mitrani RD, Castellanos A, Myerburg
     RJ, Møller for the DIAMOND Study Group. Fractal analysis and time- and frequency-domain
     measures of heart rate variability as predictors of mortality in patients with heart failure. Am J
     Cardiol 2001; 87:178-182.

140. Mäkikallio TH, Huikuri HV, Mäkikallio A, Sourander LB, Mitrani RD, Agustin Castellanos
     A, Myerburg RJ. Prediction of sudden cardiac death by fractal analysis of heart rate
     variability in elderly subjects. J Am Coll Cardiol 2001; 37:1395-402.

141. Jokinen V, Syvänne M, Mäkikallio TH, Airaksinen KEJ, Huikuri HV. Temporal age-related
     changes in spectral, fractal and complexity characteristics of heart rate variability. Clinical
     Physiology 2001; 21:273-281.

142. Hautala A, Tulppo M, Mäkikallio TH, Laukkanen R, Nissila S, Huikuri HV.Changes in
     cardiac autonomic regulation after prolonged maximal exercise. Clin Physiol, 2001; 21:238-
     245.

143. Vikman S, Yli-Mäyry S, Mäkikallio TH, Airaksinen KE, Huikuri HV. Differences in heart
     rate dynamics before the spontaneous onset of long and short episodes of paroxysmal atrial
     fibrillation. A.N.E. 2001; 6:134-142.

144. Tapanainen JM, Still AM, Airaksinen KE, Huikuri HV. Prognostic significance of risk
     stratifiers of mortality including T wave alternans after acute myocardial infarction. Results of
     a prospective follow-up study. J Cardiovasc Electrophysiol, 2001; 12:645-652.

145. Diaz JO, Mäkikallio TH, Morillo CA, Mitrani RD, Castellanos A, Myerburg RJ, Huikuri
     HV. Heart rate dynamics before the spontaneous onset of ventricular tachyarrhythmias in
     Chagas disease. Am J Cardiol, 2001; 87:1211-1213.

146. Lopera G, Huikuri HV, Tapanainen J, Chakko S, Myerburg RJ, Castellanos A. Is abnormal
     heart rate variability a specific feature of congestive heart failure? Am J Cardiol, 2001;
     87:1123-1125.

147. Airaksinen KEJ, Huikuri HV, Huhti L, Kuusela TA, Tahvanainen KUO, Tulppo M,
     Mäkikallio T, Eckberg DL. Effects of noradrenaline on human vagal baroreflexes. Ann Med
     2001; 33:193-200.

148. Haapaniemi TH, Pursiainen V, Korpelainen JT, Huikuri HV, Sotaniemi KA, Myllylä.
     Ambulatory ECG and analysis of heart rate variability in Parkinson´s disease. J Neurol
     Neurosurg Psychiatry 2001; 70:305-310.
                                                                                               13

149. Perkiömäki JS, Zareba W, Kalaria VG, Couderc J, Huikuri HV, Moss AJ. Comparability of
     nonlinear measures of heart rate variability between long- and short-term electrocardiographic
     recordings. Am J Cardiol 2001;87(7):905-908.

150. Lund K, Arildsen H, Perkiomaki JS, Huikuri HV, May O, Pedersen AK. Bias of qt
     dispersion. A.N.E. 2001; 6(1):38-42.

151. Lund K, Perkiömäki JS, Brohet C, Zaidi M, Elming H, Pedersen CT, Huikuri HV, Nygaard
     H, Pedersen AK. Improving the reproducibility of QT dispersion measures. A.N.E. 2001;
     6:143-52.

152. Ashkenazy Y, Lewkowicz, Levitan J, Havlin S, Saermark K, Moelgaard H, Bloch Thomsen
     PE, Moller M, Hintze U, Huikuri HV. Scale-specific and scale-independent measures of
     heart rate variability as risk indicators. Europhys. Lett. 2001; 53:709-715.

153. Penttilä J, Helminen A, Jartti T, Kuusela T, Huikuri HV. Time domain, geometrical and
     frequency domain analysis of cardiac vagal outflow: effects of various respiratory patterns.
     Clin Physiol 2001; 21:365-376.

154. Tulppo MP, Mäkikallio TH, Seppänen T, Shoemaker K, Tutungi E, Hughson RL, Huikuri
     HV. Effects of pharmacological adrrenergic and vagal modulation on fractal heart rate
     dynamics. Clin Physiol, 2001; 21:515-23.

155. Perkiömäki JS, Sourander LB, Levomäki L, Räihä IJ, Puukka P, Huikuri HV. QT dispersion
     and mortality in the elderly. A.N.E. 2001; 6:183-192.

156. Ansakorpi H, Korpelainen JT, Huikuri HV, Tolonen U, Myllylä VV, Isojärvi JIT. Heart rate
     dynamics in refractory and well-controlled temporal lobe epilepsy. J Neurol Neurosurg
     Psychiatry 2002; 72:26-30.

157. Lund K, Perkiömäki JS, Brohet C, Elming H, Zaidi M, Torp-Pedersen C, Huikuri HV,
     Nygaard H, Kirstein Pedersen A. The prognostic accuracy of different QT interval measures.
     A.N.E. 2002; 7:10-16.

158. Mahon NG, Hedman AE, Padula M, Gang Y, Savelieva I, Waktare JEP, Malik MM, Huikuri
     HV, McKenna WJ. Fractal correlation properties of R-R interval dynamics in asymptomatic
     relatives of patients with dilated cardiomyopathy. J Eur Heart Fail 2002; 4:151-158.

159. Mäkikallio TH, Huikuri HV, Myerburg RJ, Seppänen T, Kloosterman M, Interian A Jr,
     Castellanos A, Mitrani RD. Differences in the activation patterns between sustained and self-
     terminating episodes of ventricular fibrillation. Ann Med 2002; 34:130-135.

160. Laitio TT, Mäkikallio TH, Huikuri HV, Kentala ESH, Uotila P, Jalonen JR, Helenius H,
     Hartiala J, Yli-Mäyry S, Scheinin H. Relation of heart rate dynamics to the occurence of
     myocardial ischemia after coronary artery bypass grafting. Am J Cardiol 2002; 89:1176-1181.

161. Ridha M, Mäkikallio TH, Lopera G, Pastor J, de Marchena E, Chakko S, Castellanos A,
     Myerburg RJ, Huikuri HV. Effects of carvedilol on heart rate dynamics with congestive
     heart failure. A.N.E. 2002; 7:133-138.
                                                                                              14

162. Still A-M, Huikuri HV, Airaksinen JKE, Koistinen MJ, Kettunen R, Hartikainen J, Mitrani
     RD, Castellanos A, Myerburg RJ, Raatikainen PMJ. Impaired negative chronotrophic
     response to adenosine in patients with inappropriate sinus tachycardia. J Cardiovasc
     Electrophysiol 2002; 13:557-562.

163. Jari M Tapanainen, Poul Erik Bloch Thomsen, Lars Kober, Christian Torp-Pedersen, Timo H.
     Mäkikallio, Aino-Maija Still, Kai S. Lindgren, Heikki V. Huikuri. Fractal analysis of heart
     rate variability and mortality after an acute myocardial infarction. Am J Cardiol 2002; 90:347-
     352.

164. Pietilä E, Fodstad H, Niskasaari E, Laitinen PJ, Swan H, Savolainen M, Kesäniemi YA,
     Kontula K, Huikuri HV. Association between HERG K897T polymorphism and QT interval
     in middle-aged Finnish women. J Am Coll Cardiol 2002; 40:511-514.

165. Kakko S, Elo T, Tapainen J.M, Huikuri HV, Savolainen MJ. Polymorphisms of genes
     affecting thrombosis and risk of myocardial infarction. Eur J Clin Invest 2002; 32:643-648.

166. Pursiainen V, Haapaniemi TH, Korpelainen JT, Huikuri HV, Sotaniemi KA, Myllylä VV.
     Circadian heart rate variability in Parkinson´s disease. J Neurol 2002;249:1535-1540.

167. Niemelä R, Hakala M, Huikuri HV, Airaksinen KEJ. Comprehensive study of autonomic
     function in a population with primary Sjögren´s syndrome. No evidence of autonomic
     involvement. J Rheumatol 2003; 30:74-9.

168. Lindgren KS, Raatikainen PMJ, Airaksinen JKE, Huikuri HV. Relationship between the
     frequency of paroxysmal episodes of atrial fibrillation and pulmonary venous flow pattern.
     Europace 2003; 5:17-23.

169. Nissinen SI, Mäkikallio TH, Seppänen T, Tapanainen JM, Salo M, Tulppo MP, Huikuri HV.
     Heart rate recovery after exercise as a predictor of mortality among survivors of acute
     myocardial infarction. Am J Cardiol 2003;91:711-714.

170. Jokinen V, Ukkola O, Airaksinen KEJ, Koistinen JM, Ikäheimo MJ, Kesäniemi YA, Huikuri
     HV. Temporal changes in cardiovascular autonomic regulation in type II diabetic patients:
     Association with coronary risk variables and progression of coronary artery disease. Ann Med
     2003;35:216-223.

171. Huikuri HV, Mahaux V, Bloch-Thomsen P-E for the CARISMA Investigators. Cardiac
     arrhythmias and risk stratification after myocardial infarction: Results of the CARISMA Pilot
     Study. PACE 2003;26(1Pt 2):1-4.

172. Lopera G, Castellanos A, Moleiro F, Huikuri HV, Myerburg RJ. Chronic inappropriate sinus
     tachycardia in elderly females. A.N.E. 2003;8:139-143.

173. Tulppo MP, Hautala A, Mäkikallio TH, Laukkanen RT, Nissilä S, Hughson RL, Huikuri HV.
     Effects of aerobic training on heart rate dynamics in sedentary subjects. Journal Appl Physiol
     2003;95:364-372.
                                                                                                15

174. Lindgren KS, Mäkikallio TH, Seppänen T, Raatikainen P, Castellanos A, Myerburg RJ,
     Huikuri HV. Heart rate turbulence after ventricular and atrial premature beats in subjects
     without structural heart disease. Journal Cardiovasc Electrophysiol 2003;14:447-452.

175. Vikman S, Mäkikallio TH, Yli-Mayry S, Nurmi M, Airaksinen KE, Huikuri HV. Heart rate
     variability and recurrence of atrial fibrillation after electrical cardioversion. Ann Med
     2003;35(1):36-42.

176. Huikuri HV, Tapanainen JM, Lindgren K, Raatikainen P, Mäkikallio TH, Airaksinen KEJ,
     Myerburg RJ. Prediction of sudden cardiac deth after myocrdial infarction in the beta-
     blocking era. J Am Coll Cardiol 2003;42(4):652-658.

177. Hautala AJ, Mäkikallio TH, Kiviniemi A, Laukkanen RT, Nissilä S, Huikuri HV, Tulppo
     MP. Cardiovascular autonomic function correlates with the response to aerobic training in
     healthy sedentary subjects. Am J Physiol Heart Circ Physiol 2003;285(4):H1747-52 .

178. Jokinen V, Tapanainen JM, Seppänen T, Huikuri HV. Temporal changes and prognostic
     significance of measures of heart rate dynamics after acute myocardial infarction in the beta-
     blocking era. Am J Cardiol 2003;92(8).907-912.

179. Loimaala A, Huikuri HV, Kööbi T, Rinne M, Oja P, Turjanmaa V, Parkkari J, Vuori I.
     Exercise training improves baroreflex sensitivity in non-insulin dependent men. Diabetes
     2003;52:1837-1842.

180. Hautala AJ, Mäkikallio TH, Seppänen T, Huikuri HV, Tulppo MP. Short-term correlation
     properties of R-R interval dynamics at different exercise intensity levels. Clin Physiol Funct
     Imaging 2003;23:215-223.

181. Luukinen H, Laippala P, Huikuri HV. Depressive symptoms and the risk of sudden cardiac
     death among the elderly. Eur Heart J, 2003;24:2021-2026.

182. Penttilä J, Helminen A, Jartti T, Kuusela T, Huikuri HV, Tulppo MP, Scheinin H. Effect of
     cardiac vagal outflow on complexity and fractal correlation properties of heart rate dynamics.
     Autonomic and Autacoid Pharmacology 2003;23:173-179.

183. Tapanainen JM, Lindgren KS, Mäkikallio TH, Vuolteenaho O, Leppäluoto J, Huikuri HV.
     Natriuretic peptides as predictors of non-sudden and sudden cardiac death after acute
     myocardial infarction in the -blocking era. J Am Coll Cardiol 2004;43:757-63.

184. Laitio TT, Huikuri HV, Mäkikallio TH, Jalonen J, Kentala ESH, , Helenius H, Pullisaari O,
     Hartiala J, Scheinin H. The breakdown of fractal heart rate dynamics predicts prolonged
     postoperative myocardial ischemia. Anesth Analg 2004;98:1239-1244.

185. Peltola MA, Seppänen T, Mäkikallio TH, Huikuri HV. Effects and significance of premature
     beats on fractal correlation properties of R-R intervals dynamics. A.N.E 2004;9:127-35.

186. Hautala AJ, Mäkikallio TH, Kiviniemi A, Laukkanen RT, Nissilä S, Huikuri HV, Tulppo
     MP. Heart rate dynamics after controlled training followed by a home-based exercise
     program. Eur J Appl Physiol 2004;92:289-297.
                                                                                                 16

187. Junttila MJ, Raatikainen MJP, Karjalainen J, Kauma H, Kesäniemi YA, Huikuri HV.
     Prevalence and prognosis of subjects with Brugada-type ECG pattern in a young and middle-
     aged Finnish population. Eur Heart J, 2004;25:874-878.

188. Virtanen R, Jula A, Huikuri H, Kuusela T, Helenius H, Ylitalo A, Voipio-Pulkki L-M,
     Kauma H, Kesäniemi YA, Airaksinen J. Increased pulse pressure is associated with reduced
     baroreflex sensitivity. Journal of Human Hypertension 2004;18:247-252.

189. Mäkikallio AM, Mäkikallio TH, Korpelainen JT, Sotaniemi KA, Huikuri HV, Myllylä VV.
     Heart rate dynamics predict poststroke mortality. Neurology 2004;62:1822-1826.

190. Airaksinen KEJ, Koivikko ML, Niemelä MJ, Tahvanainen KUO, Linnaluoto M, Huikuri
     HV. Diabetes and haemodynamic reactions to acute coronary occlusion. Int J Cardiol
     2004;95:237-244.

191. Majamaa-Voltti K, Majamaa K, Peuhkurinen K, Mäkikallio TH, Huikuri HV.
     Cardiovascular autonomic regulation in patients with 3243A>G mitochondrial DNA
     mutation. Ann Med 2004;36:225-231.

192. Ahvenvaara T, Uusimaa P. Huikuri HV, Raatikainen MJP. Eteislepatuksen
     katetriablaatiohoito. Suomen Lääkärilehti 2004;23:2355-2361.

193. Ansakorpi H, Korpelainen JT, Tanskanen P, Huikuri HV, Koivula A, Tolonen U, Pyhtinen J,
     Myllylä VV, Isojärvi JIT. Cardiovascular regulation and hippocampal sclerosis. Epilepsia
     2004;45(8):933-939.

194. Tulppo MP, Huikuri HV, Tutungi E, Kimmerly DS, Gelb AW, Hughson RL, Mäkikallio
     TM, Shoemaker JK. Feedback effects of circulating norepinephrine on sympathetic outflow in
     healthy subjects. Am J Physiol 2005;288:H710-H715.

195. Kiviniemi AM, Hautala AJ, Seppänen T, Mäkikallio TH, Huikuri HV, Tulppo MP.
     Saturation of high-frequency oscillations of R-R intervals in healthy subjects and patients
     after acute myocardial infarction during ambulatory conditions. Am J Physiol Heart Circ
     Physiol 2005;287:H1921-1927.

196. Vikman S, Lindgren K, Mäkikallio TH, Yli-Mäyry S, Airaksinen KEJ, Huikuri HV. Heart
     rate turbulence after atrial premature beats before spontaneous onset of atrial fibrillation. J
     Am Coll Cardiol 2005;45:278-284.

197. Raatikainen MJP, Jokinen V, Virtanen V, Hartikainen J, Hedman A, Huikuri HV and for the
     CARISMA INVESTIGATORS. Microvolt T-wave alternans during exercise and pacing in
     patients with acute myocardial infarction. PACE 2005;28:Suppl 1:S193-7.

198. Kaikkonen KS, Kakko S, Kortelainen M-L, Tapanainen JM, Savolainen MJ, Kesäniemi YA,
     Huikuri HV, Savolainen E-R. The -1C to T Polymorphism in the Annexin A5 Gene is not
     Associated with the Risk of Acute Myocardial Infarction or Sudden Cardiac Death in Middle-
     aged Finnish Males. Scand J Clin Lab Invest 2005;65:133-140.
                                                                                                17

199. Still A-M, Raatikainen MJP, Ylitalo A, Kauma H, Ikäheimo M, Kesäniemi YA, Huikuri HV.
     Prevalence, characteristics and natural course of inappropriate sinus tachycardia. Europace
     2005;7(2):104-112.

200. Koivikko ML, Salmela PI, Airaksinen KEJ, Tapanainen JS, Ruokonen A, Mäkikallio TH,
     Huikuri HV. Effects of Insulin-induced Hypoglycemia on Cardiovascular Autonomic
     Regulation in Type 1 Diabetes. Diabetes 2005;54(3):744-750.

201. Stein PK, Domitrovich PP, Huikuri HV, Lkleiger RE; Cast Investigators. Traditional and
     nonlinear heart rate variability are each independently associated with mortality after
     myocardial infarction. J Cardiovasc Electrophysiol 2005;16(1):13-20.

202. Vaisanen MA, Vainio OM, Raekallio MR, Hietanen H, Huikuri HV. Results of 24-hour
     ambulatory electrocardiography in dogs undergoing ovariohysterectomy following
     premendication with medetomidine or acepromazine. J Am Vet Med Assoc. 2005;226(5):738-
     745.

203. Mäkikallio TH, Barthel P, Schneider R, Bauer A, Tapanainen JM, Tulppo MP, Schmidt G,
     Huikuri HV. Prediction of sudden cardiac death after acute myocardial infarction; Role of
     Holter monitoring in the modern treatment era. Eur Heart J 2005;26:762-769.

204. Mäkikallio AM, Mäkikallio TH, Korpelainen JT, Vuolteenaho O, Tapanainen JM, Ylitalo K,
     Sotaniemi KA, Huikuri HV, Myllylä VV. Natriuretic peptides and mortality after stroke.
     Stroke 2005; 36(5):1016-1020.

205. Jokinen V, Sourander LB, Karanko H, Mäkikallio TH, Huikuri HV. Changes in
     cardiovascular autonomic regulation among elderly subjects - follow-up of sixteen years.
     Annals of Medicine 2005;37:206-212.

206. Tulppo MP, Kiviniemi AM, Hautala AJ, Kallio M, Seppänen T, Mäkikallio TH, Huikuri HV.
     Physiological background of the loss of fractal heart rate dynamics. Circulation
     2005;19;112(3):314-319.

207. Wu Z-K, Vikman S, Laurikka J, Pehkonen E, Iivainen T, Huikuri HV, Tarkka MR.
     Nonlinear heart rate variability in CABG patients and the preconditioning effect. European
     Journal of Cardio-thoracic Surgery 2005;28:109-113.

208. Ronkainen E, Ansakorpi H, Huikuri HV, Myllylä VV, Isojärvi JIT, Korpelainen JT.
     Suppressed circadian heart rate dynamics in temporal lobe epilepsy. J Neurol Neurosurg
     Psychiatry 2005;76:1382-1386.

209. Hautala AJ, Kiviniemi AM, Mäkikallio TH, Kinnunen H, Nissilä S, Huikuri HV, Tulppo
     MP. Individual differences in the responses to endurance and resistance training. Eur J Appl
     Physiol 2006;96:535-542.

210. Perkiömäki JS, Hyytinen-Oinas Miia, Karsikas M, Seppänen T, Hnatkova K, Malik M,
     Huikuri HV. Usefulness of T-wave loop and QRS comblex loop to predicts mortality after
     acute myocardial infarction. Am J Cardiol 2006;97:353-360.
                                                                                             18

211. Ronkainen E, Korpelainen JT, Heikkinen E, Myllylä VV, Huikuri HV, Isojärvi JIT. Cardiac
     autonomic control in patients with refractory epilepsy bfore and during vagus nerve
     stimulation treatment: A one-year follow-up study. Epilepsia 2006;47:556-562.

212. Hautala AJ, Rankinen T, Kiviniemi AM, Mäkikallio TH, Huikuri HV. Bouchard C, Tulppo
     MP. Heart rate recovery after maximal exercise associated with acetylcholine receptor M2
     (CHRM2) gene polymorphism. Am J Physiol Heart Circ Physiol 2006;291:H459-H466.

213. Linna EH, Perkiömäki JS, Karsikas M, Seppänen T, Savolainen M, Kesäniemi YA,
     Mäkikallio T, Huikuri HV. Functional significance of KCNH2 (HERG) K897T
     polymorphism for cardiac repolarization assessed by analysis of T-wave morphology. Ann
     Noninvasive electrocardiol 2006;11(1):57-62.

214. Mäkikallio TH, Barthel P, Schneider R, Bauer A, Tapanainen JM, Tulppo MP, Perkiömäki
     JS, Schmidt G, Huikuri HV. Frequency of sudden cardiac death among acute myocardial
     infarction survivors with optimised medical and revascularization therapy. Am J Cardiol
     2006;97(4):480-4.

215. Kiviniemi AM, Hautala AJ, Mäkikallio TH, Seppänen T, Huikuri HV, Tulppo MP. Cardiac
     vagal outflow after aerobic training by analysis of high-frequenct oscillation of the R-R
     interval. Eur J Appl Physiol 2006;96(6):686-92.

216. Laitio TT, Huikuri HV, Koskenvuo J, Jalonen J, Mäkikallio TH, Helenius H, Kentala ES,
     Hartiala J, Scheinin H. Long-term alterations of heart rate dynamics after coronary artery
     bypass graft surgery. Anesth Analg 2006;102(4):1026-31.

217. de Sousa MR, Huikuri HV, Lombardi F, Perez AA, Gomes ME, Lins Barros MV, Val Barros
     VC, Costa Rocha MO, Pinho Ribeiro AL. Abnormalities in fractal heart rate dynamics in
     chagas disease. Ann Noninvasive Electrocardiol 2006;11(2):145-53.

218. Bauer A, Kantelhardt JW, Barthel P, Schneider R, Mäkikallio TH, Ulm K, Hnatkova K,
     Schöning A, Huikuri HV, Bunde A, Malik M, Schmidt G. Deceleration capacity of heart rate
     as a predictor of mortality after myocardial infarction: Cohort study. Lancet
     2006:367(9523):1674-81.

219. Kaikkonen K; Kortelainen M-L; Linna E, Huikuri HV. Family History and the Risk of
     Sudden Cardiac Death as a Manifestation of an Acute Coronary Event. Circulation
     2006;114:1462-1467

220. Raatikainen MJP, Laine A, Uusimaa P, Virtanen V, Ylitalo K, Huikuri HV. Eteisvärinän
     katetriablaatiohoidon aiheet ja tulokset. Suomen Lääkärilehti 2006;35(61):3435-3442.

221. Mäkikallio TH, Huikuri HV. Association between usage of beta-blocking medication and
     benefit implantable cardioverter therapy. Am J Cardiol 2006;98:1245-1247.

222. Kiviniemi AM, Tulppo MP, Wichterle D, Hautala AJ, Tiinanen S, Seppänen T, Mäkikallio
     TH, Huikuri HV. Novel spectral indexes o heart rate variability as predictors of sudden and
     non-sudden cardiac death after an acute myocardial infarction. Annals of Medicine
     2007;39:54-62.
                                                                                                19

223. Junttila MJ, Raatikainen MJP, Perkiömäki JS, Hong K, Brugada R, Huikuri HV. Familial
     clustering of lone atrial fibrillation in patients with saddleback-type ST-segment elevation in
     right precordial leads. Eur Heart J 2007;28:463-468.



REVIEW ARTICLES AND EDITORIALS

224. Huikuri HV. Sepelvaltimotautiin liittyvä sydämenpysähdys ja hoidon valinta elvytyksen
     jälkeen. (Cardiac arrest and treatment of patients after aborted death in patients with ischemic
     heart disease, review, Engl. transl). Duodecim 1989, 105: 751-757.

225. Koistinen MJ, Huikuri HV. Diabeetikon oireeton sydälihasiskemia. Lääkärilehti 1991, 14:
     1360-1364.

226. Huikuri HV. Lääkkeiden asema rytmihäiriöiden pitkäaikaishoidossa. Duodecim.
     Pääkirjoitus. (Role of antiarrhythmic drugs in the treatment of cardiac arrhythmias. editorial,
     Engl. transl). Duodecim 1992; 108: 1158-60.

227. Huikuri HV, Yli-Mäyry S. Predicting cardiac-related death after bypass surgery. Card Board
     Rev 1993, 10: 46-52.

228. Huikuri HV. Eteisvärinän hoito. (Treatment of atrial fibrillation, review, Engl. transl)
     Suomen Lääkärilehti 1993, 48: 1745-1750.

229. Huikuri HV, Koistinen MJ, Yli-Mäyry S, Airaksinen KEJ, Ikäheimo MJ.
     Supraventrikulaarisen takykardian katetriablaatiohoito. (Catheter ablation of supraventricular
     tachycardias, review, Engl. transl) Duodecim 1993; 109: 1459-1464.

230. Huikuri HV, Myerburg RJ. Alterations of heart rate variability associated with spontaneous
     ventricular arrhythmias. (review) Primary Cardiology 1994; 20: 24-28.

231. Heikki Huikuri. Kammiotakykardioiden luokittelu, diagnosointi ja hoito. (Diagnosis,
     classification and treatment of ventricular tachyarrhythmias, review, Engl. transl) Suomen
     Lääkärilehti 1994; 49; 27: 2641 - 2645.

232. Airaksinen KEJ, Linnaluoto M, Ikäheimo M, Huikuri HV, Koistinen MJ, Takkunen J.
     Sepelvaltimoiden varjoainekuvauksiin päässeet potilaat OYKS: ssa: Kehityssuuntia vuosilta
     1981 - 1992. Suomen Lääkärilehti 1994; 49: 290-295.

233. Airaksinen KEJ, Linnaluoto M, Kokkonen T, Pölkki H, Huikuri HV, Koistinen MJ,
     Ikäheimo M. Sepelvaltimoiden pallolaajennushoito. Onnistuminen, komplikaatiot ja
     restenoosin esiintyminen OYKS:ssa vuosina 1984 - 1991. Suomen Lääkärilehti 1994; 49:
     545-550.

234. Huikuri HV, Valkama JO, Niemelä MJ, Airaksinen KEJ. Sydämen sykevaihtelun
     mittaaminen ja merkitys. (Clinical significance and measurement of heart rate variability,
     review, Engl. transl). Duodecim 1995; 111: 307-314.

235. Huikuri HV. Heart rate variability in coronary artery disease. J Int Med 1995; 237: 349-357.
                                                                                              20



236. Huikuri HV. Toivonen L. Tahdistinhoito kehittyy nopeasti. (Advancements in pacemaker
     therapy, editorial, Engl. transl) Suomen Lääkärilehti 1995; 50:3550.

237. Huikuri HV. Tahdistinpotilaan ongelmat seuranta-aikana. (Problems in follow-up of patients
     with permanent pacemaker, review, English transl.) Suomen Lääkärilehti 1995; 50: 3561-
     3565.

238. Huikuri HV. Rytmihäiriöiden vaikutus elämänlaatuun. (Influence of cardiac arrhythmias on
     quality of life, editorial, Engl. trans.). Duodecim 1996; 111: 2381-2382.

239. Yli-Mäyry S, Korhonen P, Koistinen J, Viitasalo M, Parikka H, Huikuri H, Toivonen L.
     Terveen sydämen kammiotakykardia. (Idiopathic ventricular tachycardia, review, Engl.
     Transl) Duodecim , 1996; 112:207-216.

240. Huikuri HV. Heart rate abnormalities as a precursor of life-threatening ventricular
     tachyarrhythmias. Card Rev, 1996, 13:31-35.

241. Huikuri HV. Abnormal dynamics of ventricular repolarisation - A new insight into
     mechanisms of ventricular tachyarrhythmias (editorial). Eur Heart J 1997;18:893-895.

242. Huikuri HV. Rytmihäiriöiden hoito sydämen vajaatoiminnassa. Duodecim 1977; 113:973-
     977.

243. Huikuri HV. Heart rate dynamics and vulnerability to ventricular tachyarrhythmias. Ann
     Med 1997; 29:321-325.

244. Perkiömäki JS., Huikuri HV.. Vulnerability to ventricular tachycardia and ventricular
     fibrillation after myocardial infarction. Cardiology Review, August 1998; 15:8:17-21.

245. Raatikainen MJP, Huikuri HV. Amiodaroni rytmihäiriöiden hoidossa. Duodecim 1998;
     114:1923-36.

246. Huikuri HV. Treatment and prevention of life-threatening arrhythmia. Northern Medicine
     1998; 17-18.

247. Huikuri HV, Makikallio TH, Airaksinen KEJ, Mitrani R, Castellanos A, Myerburg RJ.
     Measurement of heart rate variability – A clinical tool or a research toy? J Am Coll Cardiol
     1999; 34:1878-83.

248. Huikuri HV. Routine tests should be challenged in cardiology. (Editorial) Eur Heart J 2000;
     21:87-91.

249. Lopera G, Huikuri HV, Makikallio TH, Castellanos A, Myerburg R. Ischemic sudden
     cardiac death: Critical analysis of risk markers. Rev Esp Cardiol 2000;53(4):568-578.

250. Mäkikallio TH, Tulppo MP, Seppänen T. Huikuri HV. Analysis of nonlinear heart rate
     dynamics in cardiac arrhythmias. Herzschr Elektrophys 2000; 11:131-138.
                                                                                              21

251. Huikuri H. Effect of stored electrograms on management in the paced patient. Am J Cardiol
     2000; 86(suppl): 101K-103K.

252. Huikuri H. Risk stratification of sudden cardiac death. Everyday Problems in Clinical
     Cardiology 2000; 10:3-8.

253. Huikuri HV, Castellanos A, Myerburg R. Sudden death due to cardiac arrhythmias. N Eng J
     Med 2001; 345:1473-1482.

254. Huikuri HV, Mäkikallio TH. Heart rate variability in ischemic heart disease. J Auton
     Nervous System, 2001; 90:96-101.

255. Lombardi F, Mäkikallio TH, Myerburg RJ, Huikuri HV. Sudden cardiac death: role of heart
     rate variability to identify patients at risk. Cardiovascular Res, 2001; 50:210-217.

256. Huikuri HV. QT dispersion - What does it mean? Cardiovascular Drugs and Therapy 2001;
     15, 299-300.

257. Raatikainen P, Huikuri HV. Eteisvärinän ablaatiohoito. Duodecim 2001; 117-1997-9.

258. Huikuri HV. Kardiologien määrä ja koulutus Länsi-Euroopan maissa – suuri paradoksi.
     Suomen Lääkärilehti 2001;38:3863-3865.

259. Mäkikallio TH, Tapanainen JM, Tulppo MP, Huikuri HV. Clinical applicability of heart rate
     variability analysis by methods based on nonlinear dynamics. Cardiovasc Electrophysiology
     Review 2002; 6:250-255.

260. Heikki V. Huikuri. Dispersion of repolarization and the autonomic system - Can we predict
     Torsade de Pointes? Cardiovascular Drugs and Therapy 2002; 16:93-99.

261. Raatikainen M, Huikuri H. Management of atrial fibrillation in patients with implantable
     cardioverter defibrillator. Do all need a dual chamber device? Eur Heart J 2002; 23: 1412-
     1414.

262. Raatikainen MJ, Yli-Mäyry S, Huikuri HV. Miten tutkin ja hoidan kammiolisälyöntejä?
     Duodecim 2002; 118:145-54.

263. Huikuri HV, Castellanos A, Myerburg RJ. Sudden death duo to cardiac arrhythmias.
     Resdponse to a letter New Engl J Med 2002; 346:926-947.

264. Huikuri HV, Mäkikallio TH, Raatikainen MJP, Perkiömäki J, Castellanos A, Myerburg RJ.
     Prediction of sudden cardiac death. Appraisal of the studies and methods assessing the risk of
     sudden arrhythmic death. Circulation 2003;108:110-115.

265. Raatikainen PMJ, Huikuri HV. Onko ACE:n estäjillä käyttöä eteisvärinän hoidossa?
     Duodecim 2003;119:1505-7.

266. Huikuri HV, Mäkikallio TH, Perkiömäki J. Measurement of heart rate variability by methods
     based on nonlineaer dynamics. J Electrocardiol 2003;36 Suppl:95-9.
                                                                                              22

267. Huikuri HV, Tapanainen JM, Mäkikallio TH. Reply to a letter to the editor: Natriuretic
     peptide after myocardial infarction and candidacy for implantable cardioverter-defibrillator
     therapy. JACC 2004;44:1529.

268. Tulppo MP, Huikuri HV. Origin and significance of heart rate variability. JACC
     2004;43:2278-80.

269. Raatikainen MJP, Huikuri HV. Rytmihäiriötahdistin - kenelle? Suomen Lääkärilehti
     2004;3:163-168.

270. Huikuri HV. Prediction of sudden cardiac death after myocardial infarction. Cardiology
     Review 2004;21:30-33.

271. Laitio T, Kuusela T, Huikuri HV, Jalonen J, Kentala E, Mäkikallio T, Helenius H, Pullisaar
     O, Hartiala J, Scheinin H. Letter to the editor;Prediction of postoperative myocardial ischemia
     by fractal heart rate dynamics. Anesth analg 2005;100:289-301.

272. Perkiömäki JS, Mäkikallio TH, Huikuri HV. Fractal and complexity measures of heart rate
     variability. Clinical and Experimental Hypertension 2005;27(2-3):149-158.

273. Raatikainen MJP, Huikuri HV for the CARISMA Investigators. Microvolt T-wave alternans
     during exercise and pacing in patients with acute myocardial infarction. Letter to the Editor.
     PACE 2005;28:1.

274. Toivonen L, Järvenpää J, Swan H, Junttila J, Mäkikallio T, Huikuri H, Viitasalo M.
     Brugadan oireyhtymä - uusi tulokas periytyvien rytmihäiriösairauksien hoitoon. Duodecim
     2005;121:1301-8.’

275. Raatikainen P, Askonen K, Halinen M, Huikuri H, Jäättelä A, Koistinen J, Lepojärvi M,
     Mäkijärvi M, Tikkanen H, Virtanen V, Hartikainen J, Toivonen L. Käypä hoito-suositus.
     Eteisvärinä. Duodecim 2005;121:2470-94.

276. Raatikainen P, Askonen K, Halinen M, Huikuri H, Jäättelä A, Koistinen J, Lepojärvi M,
     Mäkijärvi M, Tikkanen H, Virtanen V. Käypä hoito-suositus. Eteisvärinä. Duodecim
     2006;122:1457-8.

277. Erola T, Haapaniemi T, Heikkinen E, Huikuri H, Myllylä V. Subthalamic nucleus deep brain
     stimulation does not alter long-term heart rate variability in Parkinson´s disease. Clin Auton
     Res 2006;16:286-288.

278. Huikuri H. Katetriablaation historia. -Sydänääni Teemanumero Rytmihäiriöiden
     katetriablaatiohoito 2006;17;5A:4-6.


CASE REPORTS

279. Huikuri HV, Groundstroem KW, Ikäheimo MJ. Right ventricular cardiomyopathy (Engl.
     transl). Oikean kammion kardiomyopatia. Duodecim 1987, 35: 102-104.
                                                                                                23

280. Glicksman F, Zaman L, Huikuri H, Castellanos A, Myerburg RJ. Reversible failure of
     automatic implantable cardioverter- defibrillator to sense ventricular tachycardia early after
     open-heart surgery. Am J Cardiol 1988, 62: 833-35.2

281. Huikuri HV, Mallon SM, Myerburg RJ. Cardiac arrest due to spontaneous coronary artery
     dissection in a patient with coronary ectasia. A case report. Angiology 1991, 42: 148-151.

282. Huikuri H, Koistinen J, Yli-Mäyry S, Airaksinen J. Execarebation of supraventricular
     tachycardias during pregnancy (Engl. transl.) Surpaventrikulaarisen takykardiaoireiston
     vaikeutuminen raskauden aikana. Duodecim 1995; 111: 351-354.

283. Kettunen R, Huikuri HV, Oikarinen A, Takkunen JT. Methotrexate-linked ventricular
     arrhythmias. Acta Derm Venereol 1995; 75:391-392

284. Lepojärvi M, Salmela E, Huikuri H, Kärkölä P. Repair of an aneurysm of the left main
     coronary artery. Ann Thoragic Surg, 1996; 61:1247-1249.

285. Mäkikallio TH, Huikuri HV. Risks in risk stratification: What is relevant in practice?
     Circulation 2002; 105:e69-70.

286. Anttonen O, Kokkonen L, Huikuri HV. Lyhyeen QT-aikaan liittyvä sydämenpysähdys.
     Duodecim 2004;120:2915-18.

287. Mäkikallio TH, Niemelä M, Kervinen K, Jokinen V, Ylitalo K, Satta J, Juvonen J, Huikuri
     H. Vasemman sepelvaltimon ja aortan dissektoituma pallolaajennuksessa: vasemman
     päärungon hätästenttaus. Duodecim 2007;123:681–4.



CHAPTERS IN BOOKS

268. Myerburg RJ, Kimura S, Kozlovskis L, Basset AL, Huikuri H, Castellanos A. Arrhythmias
     and the healed myocardial infarction, in Lethal arrhythmias resulting from myocardial
     ischemia and infarction. Eds Rosen MR, Palti Y. 1989; 229-241

269. Ruskoaho H, Huikuri H. Rytmihäiriölääkkeet (Antiarrhythmic drugs). Lääketieteellinen
     farmakologia ja toksikologia. Toim. Pelkonen Olavi, Ruskoaho Heikki. Kustannus OY.
     Duodecim. Vammalan Kirjapaino OY 1995, sivut 298-314

270. Huikuri H. Rytmihäiriöiden katetriablaatio. (Catheter ablation of arrhythmias).
     Nuorisokardiologia. toim. (eds.): Pesonen E, Wallgren E-I, Kupari M ja Huikuri H. 1998,
     sivut 169-176.

271. Huikuri H. Sydämen rytmihäiriöt (Diagnostic of cardiac arrhythmias). Kardiologia
     (Cardiology), eds. Huikuri H, Luomanmäki, Nieminen, Peuhkurinen. ss. 689-699, Duodecim
     2000.

272. Huikuri H. Eteisvärinä (Atrial fibrillation). Kardiologia (Cardiology) eds. Huikuri H,
     Luomanmäki, Nieminen, Peuhkurinen. ss. 709-721, Duodecim 2000.
                                                                                               24

273. Huikuri H. Rytmihäiriötahdistin (Implantable cardioverter-defibrillator). Kardiologia
     (Cardiology) eds. Huikuri H, Luomanmäki, Nieminen, Peuhkurinen. ss. 814-818, Duodecim
     2000.

274. Myerburg RJ, Huikuri HV, Castellanos A. Origins, Classification, and Significance of
     Ventricular Arrhythmias. Foundations of Cardiac Arrhythmias, Spooner/Rosen 2000;20:547-
     570.

275. Myllylä V.V., Korpelainen JT, Haapaniemi TH, Tolonen U, Mäkikallio TH, Tulppo MP,
     Sotaniemi KA, Huikuri HV. Cardiovascular autonomic dysregulation. Handbook of the
     autonomic nervous system in health and disease.Ed. by C.L. Bolis & J. Licinio & S. Govoni,
     New York, Marcel Dekker 2003, ss. 363-402.

276. Mäkikallio TH, Perkiömäki JS, Huikuri HV. Nonlinear dynamics of RR intervals. Dynamic
     electrocardiography. Edited by Marek Malik and A. John Camm. Blackwell Futura 2004:22-
     30.

277. Perkiömäki J, Huikuri HV. Repolarisationanalys. Elektrokardiologi. Klinik och teknik 2006
     ss. 311-343. Redaktörer: Olle Pahlm, Leif Sörnmo.



MULTICENTER STUDIES

277. Steiner G for the DAIS Project Group: Finnish Group in Oulu: Kesäniemi A, Ikäheimo M,
     Ukkola O, Salmela P, Savolainen MJ, Huikuri HV, Airaksinen J, Koistinen J, Mannermaa L,
     Ukkola L, Silaste M-L, Salovaara A: Effect of fenofibrate on progression of coronary-artery
     disease in type 2 diabetes: the Diabetes Atherosclerosis Intervention Study, a randomized
     study. Lancet 2001; 357:905-910.

278. Executive Steering Committee on behalf of the SPORTIFF III Investigators. Investigators in
     Finland: Melin J, Pohjola-Sintonen S, Halinen MO, Airaksinen J, Huttunen M, Luotola K,
     Korpilahti K, Koponen A, Huikuri HV. Stroke prevention with the oral direct thrombin
     inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation
     (SPORTIF III): randomised controlled trial.LANCET 2003;362:1691-98.

279. Talmud P.; et al & Kesäniemi, Antero for the DAIS Investigators: Finnish Group in Oulu:
     Ikäheimo M, Ukkola O, Salmela P, Savolainen M, Huikuri HV, Mannermaa L, Ukkola L,
     Salovaara A. Progression of atherosclerosis is associated with variation in the alfa1-
     antitrypsin gene. Atherosclerosis, Thrombosis and Biology, 2003:23:644-649.

280. Vakkilainen J. el al., for the DAIS Investigators: Finnish Group in Oulu: Kesäniemi A,
     Ikäheimo M, Ukkola O, Salmela P, Savolainen M, Huikuri HV, Mannermaa L, Ukkola L,
     Silaste M-L, Salovaara A. Relationship between low-density liporptein particle size, plasma
     lipoproteins, and progression of coronary artery disease. The diabetes Atherosclerosis
     Intervention Study (DAIS). Circulation 2003;107:1733-1737.

281. Nowak B, McMeekin J, Knops M, Wille B, Schröder E, Moro C, Oelher M, Castellanos E,
     Coutu B, Petersen B, Pfeil W, Kreuzer J (on behalf of the Stored EGM in Pulsarmark II and
                                                                                                  25

      Doscovery II Study Group). Validation of dual-champer pacemaker diagnostic data using
      dual-channel stored electrograms. PACE 2005;28:620-629.

282. Cleland JGF, Daubert J-C, Erdman E, Freemantle N, Gras D, Kappenberger L, Tavazzi L, for
     the Cardiac Resynchronization Heart Failure (CARE-HF) Study Investigators, (Huikuri HV,
     Finnish Study Coordinator). The effect of cardiac resynchronization on morbidity and
     mortality in heart failure. N Engl J Med 2005;352:1539-49.

283. Cleland JGF, Daubert JC, Erdman E, Freemantle N, Gras D, Kappenberger L, Klein W,
     Tavazzi L On behalf of the CARE-HF study Steering Committee and Investigators. Baseline
     characteristics of patients recruited into the CARE-HF study, (Huikuri HV, Finnish Study
     Coordinator). The European Journal of Heart Failure 2005;7:205-214.

284. Calvert MJ, Freemantle N, Yao G, Cleland JG, Billingham L, Daubert JC, Bryan S. Cost-
     effectiveness of cardiac resynchronization therapy: Results from the CARE-HF trial,
     (Huikuri HV, Finnish Study Coordinator). Eur Heart J 2005;26(24):2681-8.

285. Ansquer, J-C.; Foucher, M. et al. for the DAIS Investigators. Finnish Group in Oulu:
     Kesäniemi, Antero; Ikäheimo, Markku; Ukkola, Olavi; Salmela, Pasi; Savolainen, Markku;
     Huikuri, Heikki; Mannermaa, Liisa; Ukkola, Leena & Salovaara, Anne Fenofibrate
     reduces progression to microalbuminuria over 3 years in a placebo-controlled study in type 2
     diabetes: Results from the Diabetes Atherosclerosis Intervention Study (DAIS). - American
     Journal of Kidney Disease, 2005, vol. 45, s. 485-493.

286. Ghio S, Freemantle N, Serio A, Magrini G, Scelsi L, Pasotti M, Cleland JGF, Tavazzi L,
     (Huikuri HV, Finnish Study Coordinator). Baseline echocardiographic characteristics of
     heart failure patients enrolled in a large European multicentre trial (Cardiac
     Resynchronisation Heart Failure study) Eur J Echocardiography 2006;7:373-8 .

287. Hoppe UC, Casares JM, Eiskjaer H, Hageman A, Cleland JGF, Freemantle N, Erdman E,
     (Huikuri HV, Finnish Study Coordinator). Effect of cardiac resynchronization on the
     incidence of atrial fibrillation in patients with severe heart failure. Circulation 2006;114:18-
     25.

288. Freemantle N, Tharmanathan P, Calvert MJ, Abraham WT, Ghosh J, Cleland JGF, (Huikuri
     HV, Finnish Study Coordinator). Cardiac resynchronization for patients with heart failure
     due to left ventricular systolic dysfunction – a systematic review and meta-analysis,. The
     European Journal of Heart Failure 2006;8:433-440.

289. Cleland JGF, Daubert J-C, Erdman E, Freemantle N, Gras D, Kappenberger L, Tavazzi L,
     (Huikuri HV, Finnish Study Coordinator). Long-term effects of cardiac resynchronization
     therapy on mortality in heart failure (the Cardiac Resynchronization-Heart Failure (CARE-
     HF) trial extension phase), . Eur H J 2006;27:1928-1932.
                                                                                                 26


ABSTRACTS

1.    Huikuri HV, Koistinen J, Yli-Mäyry S, AIraksinen KEJ, Ikäheimo MJ, Myerburg RJ.
      Impaired very low frequency oscillations of heart rate in patients with life-threatening
      arrhythmias. J Am Coll Cardiol 1994; 38A

2.    Huikuri HV, Seppänen T, Linnaluoto MK, Koistinen MJ, Airaksinen KEJ, Castellanos A,
      Myerburg RJ. Complexity of R-R interval dynamics before the spontaneous onset of
      sustained ventricular tachycardia. Circulation 1994; 4 (2): I-437.

3.    Huikuri HV, Koistinen MJ, Airaksinen KEJ, Yli-Mäyry S, Ikäheimo MJ. Significance of
      perfusion of the infarct-related coronary artery for susceptibility to ventricular
      tachyarrhythmias after myocardial infarction. Circulation 1994; 4 (2).

4.    Airaksinen KEJ, Ikäheimo MJ, Peuhkurinen KJ, Yli-Mäyry S, Linnaluoto MK, Serka T,
      Huikuri HV. Effect of left anterior descending coronary artery occlusion on vagal control
      of heart rate. Significance of the pre-existent stenosis severity. Eur Heart J 1994, 15;
      Abstracts Supplement (August): P3098.

5.    Airaksinen KEJ, Karjalainen O, Huikuri HV, Ikäheimo MJ, Rantala AO, Lilja M,
      Savolainen MS, Reunanen AS, Kesäniemi YA. Baroflex sensitivity in middle-aged
      hypertensive men. Eur Heart J 1994, 15; Abstract Supplement (August): P3202.

6.    Huikuri HV, Pikkujämsä SM, Ikäheimo MJ, Airaksinen KEJ, Rantala AO, Lilja M,
      Reunanen A S, Savolainen MJ, Kesäniemi YA. Determinants of frequency domain measures
      of heart rate variability in hypertensive males. Eur Heart J 1994, 15; Abstract Supplement
      (August): P620.

7.    Karjalainen O, Airaksinen KEJ, Huikuri HV, Ikäheimo MJ, Lilja M, Rantala AO,
      Savolainen M, Reunanen AS, Kesäniemi YA. Baroflex sensitivity and cardiovascular risk
      factors in middle-aged healthy men. Eur Heart J 1994, 15; Abstract Supplement (August):
      725.

8.    Perkiömäki JS, Koistinen MJ, Yli-Mäyry S, Huikuri HV. Dispersion of the QT interval in
      patients with and without susceptibility to life-threatening arrhythmias. Eur Heart J 1994,
      15; Abstract Supplement (August): 967.

9.    Huikuri HV, Jokinen V, Seppänen T, Niemelä M, Airaksinen KEJ, Linnaluoto MK,
      Castellanos A. Reduced complexity of R-R interval dynamics in patients with coronary
      artery disease. J Am Coll Cardiol 1995; Feb.: 194A.

10.   Koistinen MJ, Perkiömäki J, Airaksinen KEJ, Yli-Mäyry S, Ikäheimo MJ, Huikuri HV.
      Effects of perfusion of the infarct related artery on risk markers of life-threatening
      arrhythmias in patients with prior myocardial infarction. PACE 1995; 18, 9(II): Abst 7.

11.   Koistinen MJ, Perkiömäki J, Yli-Mäyry S, Ikäheimo MJ, Huikuri HV. Prevalence and
      prediction of inducubility of ventricular tachyarrhythmia in patients with remote myocardial
      infarction. PACE 1995; 18, 9(II): Abst 6.
                                                                                                27

12.   Huikuri HV, Seppänen T, Koistinen MJ, Airaksinen KEJ, Ikäheimo MJ, Castellanos A,
      Myerburg RJ. Abnormalities in nonlinear complexity of RR interval dynamics in patients
      with susceptibility to spontaneous ventricular tachycardias. PACE 1995; 18, 9(II): Abst 137.

13.   Perkiömäki J, Ikäheimo MJ, Rantala A, Lilja M, Kesäniemi YA, Huikuri HV. Comparison
      of dispersion of QT interval and heart rate variability in hypertensive males with and
      without left ventricular hypertrophy. PACE 1995; 18, 9(II): Abst 138.

14.   Huikuri HV, Seppänen T, Castellanos A, Myerburg RJ. Approximate entropy of RR-
      interval dynamics and propensity to ventricular tachyarrhythmias after myocardial
      infarction. Circulation Suppl 1995; 92(8): I-97, 464.

15.   Ylitalo A, Airaksinen KEJ, Niemelä MJ, Ruskoaho H, Ikäheimo MJ, Huikuri HV.
      Determinants of reduced very low frequency oscillations of heart rate in patients with
      ischemic heart disease. Circulation Suppl 1995; 92(8): I-732, 3517.

16.   Pikkujämsä SM, Huikuri HV, Airaksinen KEJ, Ikäheimo MJ, Rantala AO, Lilja M,
      Savolainen MJ, Kesäniemi YA. Abnormalities in vagal control of heart rate in insulin
      resistance syndrome. Circulation Suppl 1995; 92(8): I-155, 734.

17.   Huikuri HV, Airaksinen KEJ, Koistinen MJ, Palmgren J-E, Linnaluoto MK, Tikkanen P,
      Sellin L. Two-dimensional vector analysis of beat-to-beat dynamics of ventricular
      repolarization. Eur J.C.P.E. 1996: 6:36

18.   Edvardsson N, Huikuri H, Kennebäck G, Timmermans A, Ullman B. Antiarrhythmic
      efficacy by a class III agent with and without betablockade in chronic atrial fibrillation - A
      double-blind randomized comparison of Dl-Sotalol, D-Sotalol and Placebo. J Am Coll
      Cardiol (Suppl) 1996; 27:46 A

19.   Mäkikallio TH, Koistinen MJ, Airaksinen KEJ, Seppänen T, Peng C-K, Goldberger AL,
      Huikuri HV. Altered RR interval dynamics and vulnerability to life-threatening
      arrhythmias: Fractal analysis. Eur Heart J (Suppl), 1996: 17:29.

20.   Ylitalo A, Airaksinen KEJ, Tahvanainen KUO, Kuusela TA, Lilja M, Rantala A, Kesäniemi
      YA, Huikuri HV. Baroreflex sensitivity in systemic hypertension. Eur Heart J (Suppl),
      1996: 17:337.

21.   Tulppo MP, Mäkikallio TH, Airaksinen KEJ, Huikuri HV. Nonlinear dynamics of heart
      rate durinh accentuated sympatho-vagal interaction. Circulation (Suppl) 1996; 94: I-431.

22.   Perkiömäki JS, Huikuri HV, Koistinen JM, Castellanos A, Myerburg RJ. Dispersion of QT
      interval and heart rate in patients with vulnerability to ventricular tachycardia and
      ventricular fibrillation. Circulation (Suppl) 1996; 94: I-625.

23.   Mäkikallio TH, Koistinen JM, Airaksinen KEJ, Seppänen T, Peng C-K, Goldberger AL,
      Huikuri HV. Heart rate dynamics in patients with and without vulnerability to ventricular
      tachyarrhythmias after a prior myocardial infarction. Circulation (Suppl) 1996, 94:I-669.
                                                                                               28

24.   Ylitalo A, Airaksinen KEJ, Huikuri HV. Modulation of baroreflex sensitivity and heart rate
      variability in hypertensive patients: Effect of combination antihypertensive therapy.
      Scandinavian Cardiovascular Journal (Suppl) 1997; 45:P67.

25.   Mäkikallio T, Ristimäki T, Airaksinen KEJ., Peng C-K, Goldberg A-L and Huikuri HV..
      Altered heart rate dynamics in patients with uncomplicated coronary artery disease.
      Scandinavian Cardiovascular Journal (Suppl) 1997; 45:P46.

26.   Loimaala A, Sievänen H, Laukkanen R, Pärkkä J, Vuori I, Huikuri H. Accuracy of the
      Polar recorder for heart rate variability assessment. Scandinavian Cardiovasvular Journal
      (Suppl) 1997; 45:P45.

27.   Jokinen V, Huikuri H, Syvänne M, Nieminen M, Airaksinen J, Ikäheimo M, Koistinen J,
      Kauma H, Kesäniemi A, Majahalme S, Niemelä K, Frick H. Cardiovascular autonomic
      regulation and progression of coronary atherosclerosis. Scandinavian Cardiovascular Journal
      (Suppl) 1997; 45:P40.

28.   Bendel S, Kettunen R, Kuikka J, Huikuri H, Hartikainen J. Effects of coronary bypass
      grafting on myocardial viability in postinfarction patients. Scandinavian Cardiovascular
      Journal (Suppl) 1997; 45:P33.

29.   Poutiainen A-M, Hartikainen J, Kettunen R, Karjalainen J, Huikuri HV. Prevalence and
      natural course of ectopic atrial tachycardia. Scandinavian Cardiovascular Journal (Suppl)
      1997; 45:21.

30.   Perkiömäki JS, Koistinen JM, Huikuri HV. Dispersion of QT interval, heart rate variability
      and spontaneous ventricular arrhythmias in survivors of ventricular fibrillation and without
      inducible ventricular tachyarrhythmia. Eur Heart J (Suppl) August 24-28, Stockholm,
      Sweden 1997; 18:199.

31.   Tulppo MP, Mäkikallio TH, Seppänen T, Laukkanen RT, Huikuri HV. Vagal modulation
      of heart rate during exercise: Effects of age and physical fitness. Eur Heart J (Suppl) 1997;
      18:115.

32.   Airaksinen KEJ, Ikäheimo MJ, Linnaluoto M, Tahvanainen KUO, Huikuri HV. Sex
      difference in autonomic and haemodynamic reactions to acute coronary occlusion. Eur Heart
      J (Suppl) 1997; 18:57.

33.   Koistinen MJ, Airaksinen KEJ, Perkiömäki JS, Mustonen J, Hartikainen J, Huikuri HV. QT
      dispersion and cardiac denervation in patients with coronary artery disease. Scandinavian
      Cardiovascular Journal (Suppl) 1997; 45:16.

34.   Mäkikallio T, Huikuri H, Seppänen T, Airaksinen KEJ, Tulppo M, Räihä I, Puukka P,
      Sourander L. Power-Law relationship of heart rate variabillity and mortality in the elderly.
      Scandinavian Cardiovascular Journal (Suppl) 1997; 45:10.

35.   Ylitalo A, Hautanen A, Airaksinen KEJ, Savolainen MJ, Kauma H, Kupari M, Kesäniemi
      AY, Huikuri HV. Baroreflex sensitivity and aldosterone synthase gene polymorphism in
      middle agend subjects. Circulation (Suppl) 1997; 96:563.
                                                                                                 29

36.   Huikuri HV, Neyround N, Koistinen JM, Coumel P, Maison-Blanche P. QT rate
      adaptation: Anew index to discriminate patients with and without ventricular arrhytmias
      following myocardial infarction? Circulation (Suppl) 1997; 96:4014.

37.   Mäkikallio TH, Huikuri HV, Airaksinen KEJ, Seppänen T, Puukka P, Räihä IJ, Sourander
      LB. Power law behavior of heart rate variability as a predictor of mortality in the elderly.
      Circulation (Suppl) 1997; 96:3248.

38.   Huikuri HV, Jokinen V, Syvänne M, Nieminen MS, Airaksinen KEJ, Ikäheimo MJ,
      Koistinen JM, Kauma H, Kesäniemi AY, Majahalme S, Niemelä K, Frick H. Heart rate
      variability and progression of coronary atherosclerosis. Circulation (Suppl) 1997; 96:3249.

39.   Huikuri HV, Mäkikallio TH, Airaksinen KEJ, Puukka P, Sourander LB. Power law
      behavior of RR-interval variability in chronic atrial fibrillation. Circulation (Suppl) 1997;
      96:3251.

40.   Airaksinen KEJ, Tahvanainen KU, Eckberg DL, Niemelä M, Ylitalo A, Huikuri HV.
      Baroreflex gain during acute coronary occlusion. Circulation (Suppl) 1997; 96:3541.

41.   Loimaala A., Sievänen H, Laukkanen R, Vuori I, H Huikuri. Accuracy of a digital real-time
      QRS-detector for heart rate variability (HRV) asssessmen. Journal of the American College
      of Cardiology (Suppl) 1998; 31:413C.

42.   Tapanainen JM, Tulppo MP, Mäkikallio TH, Seppänen T, Laukkanen RT, Huikuri HV.
      Impaired vagal modulation of heart rate during ecercise in patients after acute myocardial
      infarction. Journal of the American College of Cardiology (Suppl) 1998; 31:201C.

43.   Niemelä MJ, Koistinen MJ, Airaksinen KEJ, Huikuri HV. Impact of infarct-related artery
      patency on vulnerability to monomorphic ventricular tachycardia and ventricular fibrillation.
      Journal of the American College of Cardiology (Suppl) 1998; 31:201C.

44.   Perkiömäki JS, Levomäki L, Puukka P, Räihä IJ, Sourander LB, Huikuri HV. Maximum
      Qtc interval as a predictor of mortality in the elderly. Journal of the American College of
      Cardiology (Suppl) 1998; 31:202C.

45.   Poutiainen A-M, Koistinen MJ, Airaksinen KEJ, Hartikainen JEK, Kettunen RVJ,
      Karjalainen J, Huikuri HV. Prevalence and natural course of ectopic atrial tachycardia.
      Journal of the American College of Cardiology (Suppl) 1998; 31:202C.

46.   Mäkikallio TH, Koistinen MJ, Tulppo MP, Jordaens L, Wood N, Peng C-K, Goldberger AL,
      Huikuri HV. RR interval dynamics before the spontaneous onset of ventricular fibrillation.
      Journal of the American College of Cardiology (Suppl) 1998; 31:202C.

47.   Koistinen MJ, Perkiömäki JS, Airaksinen KEJ, Mäkikallio TH, Huikuri HV. Comparison
      of standard 12-lead and 24-hour electrocardiogram in identifying the patients with
      vulnerability to cardiac arrest. Journal of the American College of Cardiology (Suppl) 1998;
      31:202C.

48.   Mäkikallio TH, Ristimäki T, Airaksinen KEJ, Peng C-K, Goldberger AL, Huikuri HV.
      Heart rate dynamics in patients with stable angina pectoris and utility of fractal and
                                                                                                30

      comblexcity measures. Journal of the American College of Cardiology (Suppl) 1998;
      31:203C.

49.   Perkiömäki JS., Koistinen JM., Huikuri HV.. Standard 12-lead and 24-hour ambulatory
      electrogardiographic abnormalities in survivors of tachyarrhythmic cardiac arrest. Pacing
      and Clinical Electrophysiology 1998; 21:886.

50.   Poutiainen A-M, Koistinen MJ, Airaksinen KEJ, Castellanos A, Huikuri HV. Heart rate
      variability in ectopic atrial tachycardia. Pacing and Clinical Electrophysiology, Part II 1998;
      21:907.

51.   Airaksinen KEJ, Koistinen MJ, Perkiömäki JS, Niemelä M, Ylitalo A, Peuhkurinen K,
      Ikäheimo MJ, Huikuri HV. Is screening of patients fulfilling the MADIT criteria after a
      prior myocardial infarction cost-effective. Pacing and Clinical Electrophysiology 1998;
      21:929.

52.   Mäkikallio T, Hojbjergs S, Torp-Pedersen C, Peng C-K, Goldberger AL., Huikuri HV.
      Comparison of traditional and new dynamical measures of heart rate variability as predictors
      of mortality in patients with depressed left ventricular function. Cardiostim Abstract 1998;
      98;45-1.

53.   Poutiainen A-M, Koistinen MJ, Airaksinen KEJ, Castellanos A, Huikuri HV. Heart rate
      variability in ectopic atrial tachycardia. Cardiostim Abstract 1998; 45-P7.

54.   Perkiömäki JS., Levomäki L, Puukka P, Räihä IJ, Sourander LB., Huikuri HV.. Maximum
      Qtc interval as a predictor of mortality in the elderly. Cardiostim Abstract 1998; 166-1.

55.   Koistinen MJ, Airaksinen KEJ, Perkiömäki J, Niemelä M, Ylitalo A, Peuhkurinen K,
      Ikäheimo MJ., Huikuri HV.. Prevalence of patients fulfilling the madit criteria after
      myocardial infarction. Cardiostim Abstract 1998; 166-1.

56.   Airaksinen KEJ, Ylitalo A, Tahvanainen KUO, Niemelä MJ, Huikuri HV. Heart rate
      variability as a predictor of ischaemia-induced ventricular arrhythmias during acute
      coronary occlusion. Eur Heart J 1998; 19 (Abstr. Suppl): 245.

57.   Ylitalo A, Airaksinen KEJ, Hautanen A, Kauma H, Kupari M, Kesäniemi YA, White PC,
      Huikuri HV. Baroreflex sensitivity and variants of the renin angiotensin system genes. Eur
      Heart J 1998; 19 (Abstr. Suppl): 135.

58.   Mäkikallio TH, Huikuri HV, Airaksinen KEJ, Puukka P, Räihä IJ, Peng C-K, Goldberger
      AL, Sourander LB. Altered heart rate dynamics as a predictor of sudden cardiac death in a
      population of elderly subjects. Eur Heart J 1998; 19 (Abstr. Suppl): 4295.

59.   Vikman S, Yli-Mäyry S, Niemelä K, Raatikainen P, Huikuri HV. RR-Interval dynamics
      before paroxysmal atrial fibrillation. Eur Heart J 1998; 19 (Abstr. Suppl): 663.

60.   Perkiömäki JS, Levomäki L, Puukka P, Räihä IJ, Sourander LB, Huikuri HV. Maximum
      Qtc interval as a predictor of mortality in the elderly. Eur Heart J 1998; 19 (Abstr. Suppl):
      425.
                                                                                                  31

61.   Huikuri HV, Salo MA, Saarivirta A, Tikkanen P, Airaksinen KEJ. QT-Interval dynamics
      before the spontaneous onset of ventricular fibrillation. Circulation (Suppl.) 1998; 98: I-26.

62.   Mäkikallio TH, Huikuri HV, Peng C-K, Goldberger AL, Hintze U, Moller M. Fractal
      analysis of heart rate dynamics as a predictor of mortality in patients with depressed left
      ventricular function after an acute myocardial infarction. Circulation (Suppl) 1998; 98: I-25.

63.   Hedman AE, Mäkikallio TH, Huikuri HV.. Risk stratification of arrhythmic mortality after
      myocardial infarction using measures of non-linear heart rate dynamics. Circulation (Suppl)
      1998; 98: I-705.

64.   Tulppo MP, Mäkikallio TH, Laukkanen RT, Huikuri HV. Differences in vagal modulation
      of heart rate during dynamic arm and leg exercise. Medicine&Science in sports&Exercise
      (Suppl) 1998:30:S307.

65.   Castellanos A, Moleiro F, Lopera G, Huikuri H. Dynamics of the QT interval in response
      to sudden vagal-induced lengthening of the RR interval. J Am Coll Cardiol (Suppl) 1999;
      33(2): 130A.

66.   Hohnloser SH, Huikuri H, Schwartz PJ., Johan Vijgen, Roberto F. Pedretti, Samuel Levy,
      Thomas Klingenheben, Jari Tapanainen, Emilio Vanoli, A. John Camm, Douglas P. Zipes,
      Richard J. Cohen. T wave alternans in post myocardial infarction patients (ACES Pilot
      Study). J Am Coll Cardiol (Suppl) 1999; 33(2): 144A.

67.   Tapanainen J, Airaksinen KEJ, Huikuri HV. Baroreflex sensitivity and heart rate variability
      in patients with and without sustained T-wave alternans after an acute myocardial infarction.
      J Am Coll Cardiol (Suppl) 1999; 33(2): 121A.

68.   Jokinen V., Airaksinen KEJ., Huikuri HV. Temporal changes in fractal and spectral
      characteristics of heart rate variability in patients with coronary artery disease. Eur Heart J
      1999; 20:591.

69.   Tapanainen JM, Airaksinen KEJ, Huikuri HV. Baroreflex sensitivity and heart rate
      variability in patients with and without sustained T-wave alternans after an acute myocardial
      infarction. Eur Heart J 1999; 20:333.

70.   Tapanainen JM, Bloch-Thomsen PE, Rosenqvist M, Koistinen MJ, Torp-Pedersen C, Kober
      L, Huikuri HV. Fractal analysis of heart rate variability as a predictor of mortality after
      acute myocardial infarction. Eur Heart J 1999; 20:342.

71.   Tulppo MP, Mäkikallio T, Airaksinen KEJ, Huikuri HV. Physiological correlates of
      complexity of R-R interval dynamics. Eur Heart J 1999; 20:125.

72.   Reissell E, Perola M, Virolainen J, Airaksinen KJ, Ylitalo A, Huikuri H, Kupari M.
      Depressed baroreflex sensitivity is associated with angiotensin II type receptor gene
      polymorphism C1166 in adults free of clinical heart disease. Eur Heart J 1999; 20:238.

73.   Huikuri HV, Poutiainen A-M, Koistinen J, Raatikainen P, Airaksinen J, Hartikainen J,
      Kettunen R, Mitrani R, Castellanos A, Myerburg RJ. Insensitivity of inappropriate sinus
      tachycardia to adenosine. PACE 1999; 22:715.
                                                                                                 32



74.   Huikuri HV, Mitrani RD, Castellanos A, Myerburg RJ. Abnormalities in ventricular
      repolarization after appropriate implantable cardioverter-defibrillator shocks. PACE 1999;
      22:777.

75.   Tapanainen JM, Bloch Thomsen P-E, Koistinen J, Torp-Pedersen C, Kober L, Huikuri HV.
      Fractal analysis of heart rate variability as a predictor of mortality after an acute myocardial
      infarction. PACE 1999; 22:789.

76.   Vikman S, Mäkikallio TM, Yli-Mäyry S, Koivisto A-M, Reinikainen P, Airaksinen KEJ,
      Huikuri HV. A decrease in complexity of R-R interval dynamics precedes the spontaneous
      onset of atrial fibrillation. PACE 1999; 22:A48.

77.   Vikman S, Mäkikallio TM, Yli-Mäyry S, Pikkujämsä S, Airaksinen KEJ, Huikuri HV. R-R
      interval dynamics predict the perpeturation of paroxysmal episodes of atrial fibrillation.
      PACE 1999; 22:A43.

78.   Mäkikallio TH, Huikuri HV, Videbaek J, Hosp B, Hintze U, Moller M, Study Group
      DIAMOND. Comparison of fractal analysis, post-ectopic turbulence analysis and traditional
      analysis of heart rate variability as preditors of mortality in patients with heart failure.
      Circulation (Suppl) 1999; 100:2685.

79.   Mäkikallio TH, Hintze U, Huikuri HV, Mitrani RD, Castellanos A, Myerburg RJ, Videbek
      J, Møller M, The DIAMOND Study Group. Comparison of post-ectopic turbulence analysis,
      fractal analysis and traditional heart rate variability analysis as predictors of mortality in
      patients with a recent and remote myocardial infarction. J Am Coll Cardiol SupplA 2000;
      35:107A.

80.   Mäkikallio TH, Mitrani RD, Castellanos A, Myerburg RJ, Sourander LB, Räihä I, Huikuri
      HV. Altered fractal properties of heart rate dynamics as a predictor of sudden cardiac death
      in the elderly. J Am Coll CardiolSupplA 2000; 35:144A.

81.   Lopera G, Huikuri HV, Tapanainen J, Chakko S, Myerburg RJ, Castellanos A. Is abnormal
      heart rate variability a specific feature of congestive heart failure? J Am Coll Cardiol
      SupplA 2000; 35:106A.

82.   Mäkikallio TH, Huikuri HV, Mitrani RD, Mattila L, Castellanos A, Myerburg RJ. Altered
      fractal properties of R-R interval dynamics before the spontaneous onset of ventricular
      tachyarrhythmias. PACE 2000; 23:450.

83.   Huikuri HV, Koistinen J, Petersen B, Benzer W, Appl U. A new approach to symtomatic
      pacemaker patients: Results from the magnet stored E-gram Study. PACE 2000; 23:518.

84.   Vikman S, Mäkikallio TH, Yli-Mäyry S, Pikkujämsä S, Airaksinen KEJ, Huikuri HV. R-R
      interval dynamics predict the perpetuation of paroxysmal episodes of atrial fibrillation.
      PACE 2000; 23:624.

85.   Diaz JO, Mäkikallio TH, Huikuri HV, Lopera G, Mitrani RD, Castellanos A, Myerburg RJ.
      Altered heart rate dynamics before the spontenous onset of ventricular tachyarrhythmias in
      patients with chronic chagas' disease. Circulation (Suppl) 2000; 102:2140.
                                                                                                33



86.   Stein PK, Domitrovich PP, Mäkikallio TH, Huikuri HV, Kleiger RE. Non-linear but not
      time-domain indices of heart rate variability predict mortality in the cardiac arrhythmia
      suppression trial (CAST). Circulation (Suppl) 2000; 102:2396.

87.   Huikuri HV, Tapanainen JM, Still A-M, Airaksinen KEJ. Prognostic value of assessment
      of sustained T-wave alternans during the exercise test after an acute myocardial infarction:
      results of a prospective follow-up study. Europace 2000; 1:61/3.

88.   Petersen B, Huikuri H, Benzer W, Appl U, BSBME# for the European Investigtors on the
      Validiation of stored E-grams. Specifity of pacemaker diagnostics verified with stored e-
      grams. Europace 2000; 1; 153/3.

89.   Tapanainen JM, Vuolteenaho O, Leppäluoto J, Huikuri HV. Prognostic value of natriuretic
      peptides and heart rate variability in patients with optimized treatment after an acute
      myocardial infarction. J Am Coll Cardiol (supplA) 2001; 37:1262-179.

90.   Pietilä E, Fodstad H, Niskasaari E, Laitinen P, Swan H, Savolainen M, Kesäniemi A,
      Kontula K, Huikuri H. HERG K897T polymorphism and QT interval in a random middle-
      aged population. J Am Coll Cardiol(supplA) 2001;37:823

91.   Koivikko M-L, Salmela PI, Airaksinen KEJ, Tapanainen JS, Ruokonen A, Huikuri HV.
      Effects of hypoglycemia on cardiac autonomic regulation in type 1 diabetes mellitus. J Am
      Coll Cardiol (supplA) 2001; 37:1030.

92.   Huikuri HV, Tapanainen JM, Mäkikallio TH. Predictive power of life-threatening
      arrhythmia risk markers among patients with optimized treatment after acute myocardial
      infarct. Pacing and Clinical Electrophysiology 2001; 24:532.

93.   Mäkikallio TH, Huikuri HV, Kloosterman M, Interian A, Castellanos A, Myerburg RJ,
      Mitrani RD. Evidence for organized during human ventricular fibrillation: Ordered patterns
      of activation in disordered mechanical function. Pacing and Clinical Electrophysiology
      2001; 24:645.

94.   Mäkikallio TH, Huikuri HV, Seppänen T, CAstellanos A, Myerburg RJ, Mitrani RD.
      Evidence for organized dynamics in human ventricular fibrillation: ordered patterns of
      activitation in disordered mechanical function. Nordic Congress of Card. 2001, p. 12 abs. 7.

95.   Hautala A, Tulppo M, Mäkikallio TH, Seppänen T, Huikuri HV. Fractal characteristics of
      heart rate variability at different exercise intensity levels with and without vagal blockade.
      Nordic Congress of Card. 2001, p. 12 abs. 8.

96.   Bloch Thomsen PE, Saermark K, Huikuri HV, Mäkikallio TH, Levitan J, Kober L,
      Lewkowicz M, Feldman S for the DIAMOND Study Group. Multipole analysis predicts
      mortality after acute myocardial infarction. Europace Suppl 2001; 2:B7 633.

97.   Mäkikallio T, Huikuri H, Seppänen T, Kloosterman M, Interia A, Castellanos A, Myerburg
      R, Mitrani R. Evidence for organized dynamics during human ventricular fibrillation.
      Europace Suppl 2001; 2:B175 899.
                                                                                                34

98.    Nurmi M, Vikman S, Huikuri HV, Yli-Mäyry S. A decrease in complexcity of RR intervals
       precedes the paroxysmal episodes of atrial fibrillation in patients with structural heart
       disease. Europace Suppl 2001; 2:B110 962.

99.    Tulppo MP, Shoemaker K, Tutungi E, Gelb A, Kimerly D, Hughson RL, Huikuri HV.
       Effects of circulating norepinephrine of sympathetic outflow. Eur Heart J 2001; 22:P377.

100.   Tapanainen JM, Vuolteenaho O, Leppäluoto J, Huikuri HV. Prognostic value of natriuretic
       peeptides and heart rate variability in patients with optimized tratment after an acute
       myocardial infarction. Eur Heart J 2001; 22:P487.

101.   Mäkikallio T, Ridha M, Pator J, Shakko S, Mitrani R, Castellanos A, Myerburg RJ, Huikuri
       HV. Effects of carvedilol on spectral and fractal heart rate dynamics among patients with
       congestive heart failure, Eur Heart J 2001; 22:P2328.

102.   Tapanainen JM, Mäkikallio TH, Huikuri HV. Predictive value of risk markers on life-
       threatening arrhythmias in patients with optimized tratment after acute myocardial
       infarction. Eur Heart J 2001; 22:P2568.

103.   Mäkikallio T, Huikuri HV, Seppänen T, Kloosterman M, Koshy S, Interian A, Castellanos
       A, Myerburg RJ, Mitrani RD. Evidence for oragnized dynamics during human ventricular
       fibrillation: ordered patterns of activation in disordered mechanical function. Eur Heart J
       2001; 22:P3723.

104.   Huikuri HV, Lindgren K, Tapanainen J, Mäkikallio TH. Prognostic power of traditional
       and new heart rate variability indices in patients with optimized therapy after myocardial
       infarction. Results of a prospective study. Circulation 2001; 104:3014.

105.   Pietilä EH, Kortelainen M-L, Fodstad H, Laitinen PJ, Swan H, Savolainen M, Kesäniemi
       YA, Kontula K, Huikuri HV. HERG K897T polymorphism and sudden arrhythmic death
       due to acute coronary event. Circulation 2001; 104:2196.

106.   Hautala A, Tulppo M, Mäkikallio, Laukkanen R, Nissilä S, Huikuri H. Effects of aerobic
       training on heart rate dynamics: One year follow-up. European College of Sprot Science
       2001:406.

107.   Hautala A, Tulppo M, Mäkikallio T, Seppänen T, Huikuri H. Fractal characteristics of heart
       rate during different ecercise intensity levels. European College of Sprot Science 2001:415.

108.   Tulppo M, Hautala A, Mäkikallio T, Laukkanen R, Nissilä S, Hugson R, Huikuri H. Effects
       of aerobic training on fractal characteristics of heart rate behaviour. . European College of
       Sprot Science 2001:414.

109.   Hautala A, Tulppo M, Mäkikallio T, Seppänen T, Huikuri H. Fractal characteristics of heart
       rate variability at different exercise intensity levels with and without vagal blockade.
       Hjerteforum 2001; 14:112.

110.   Mäkikallio TH, Huikuri HV, Seppänen T, Castellanos A, Myerburg RJ, Mitrani RD.
       Evidence for organized dynamics in human ventricular fibrillation: Ordered patterns of
       activation in disordered mechanical function. Hjerteforum 2001; 14:112.
                                                                                                35



111.   Tulppo MP, Shoemaker K, Tutungi E, Kimerly D, Gelb A, Hughson RL. Huikuri HV.
       Effects of circulating norepinephrine on sympathetic outflow. Hjerteforum 2001; 14:130.

112.   Tulppo MP, Hautala A, Mäkikallio T, Laukkanen R, Nissilä S, Hughson R, Huikuri H.
       Harjoittelun vaikutukset sydämen sykkeen dynamiikkaan. Liikunta ja tiede, Erikoisliite
       2001, s. 41.

113.   Hautala A, Tulppo MP, Mäkikallio T, Seppänen T, Huikuri H. Sydämen sykkeen
       dynamiikka fyysisen kuormituksen aikana. Liikunta ja Tiede, Erikoisliite 2001, s. 21.

114.   Tulppo MP, Shoemaker K, Tutungi E, Kimerly D, Gelb A. Hughson RL, Mäkikallio TH,
       Huikuri HV. Korkea veren noradrenaliinipitoisuus inhiboi neuraalista sympaattista
       aktiivisuutta. Liikunta ja Tiede 2002,;5:42.

115.   Kiviniemi A, Hautala AJ, Mäkikallio TH, Nissilä S, Kinnunen H, Huikuri HV, Tulppo MP.
       Kestävyysharjoittelun onnistuminen on yhteydessä sydämen vagaaliseen säätelyyn. Liikunta
       ja Tiede 2002;5:33.

116.   Hautala AJ, Mäkikallio TH, Laukkanen RT, Nissilä S, Huikuri HV, Tulppo MP.
       Harjoittelun vaikutukset sydämen sykevaihtelub dynamiikkaan: 12 kuukauden
       seurantatutkimus. Liikunta ja Tide 2002;5:30.

117.   Nissinen SI, Mäkikallio TH, Seppänen T, Tapanainen JM, Salo M, Tulppo MP, Huikuri
       HV. Sykkeen palauttaminen ennustaa toipumista sydäninfarktipotilailla. Liikunta ja Tiede
       2002;5:17-18.

118.   Bloch Thomsen PE, Saermark K, Huikuri HV, Mäkikallio TH, Levitan J, Rikke Moerch
       Olesen, Lewkovicz, Feldman S. Multipole analysis predicts mortality after acute myocardial
       infarction. . Pacing and Clinical Electrophysiology 2002; 25:678.

119.   Lindgren KS, Raatikainen PMJ, Airaksinen JEK, Tapanainen JM, Huikuri HV. Paroxysmal
       atrial fibrillation and pulmonary venous flow pattern. Pacing and Clinical Electrophysiology
       2002; 25:252.

120.   Nissinen S, Tapanainen JM, Mäkikallio TH, Lindgren KS, Tulppo MP, Huikuri HV. After
       exercise as a predictor of mortality after an acute myocardial infarction. Pacing and Clinical
       Electrophysiology 2002; 25:253.

121.   Tapanainen JM, Vuolteenaho O, Leppäluoto J, Huikuri HV. Plasma ouabain levels as a
       predictor of mortality after acute myocardial infarction. Accepted 2002.

122.   Kiviniemi A, Hautala AJ, Mäkikallio TH, Nissilä S, Kinnunen H, Huikuri HV, Tulppo MP.
       Relationship between training response and heart rate variability in endurance athletes. 7th
       Annual Congress of the European College of Sport Science, Proceedings 2002;P850YIA:
       770.

123.   Tulppo MP, Shomaker K, Tutungi E, Kimberly D, Gelb A, Hughson RL, Huikuri HV.
       Feedback effects of circulating norepinephrine on sympathetic outflow. 7th Annual Congress
       of the European College of Sport Science, Proceedings 2002; 1:O205: 107.
                                                                                               36



124.   Tulppo MP, Hautala AJ, MäkikallioTH, Laukkanen RM, Nissilä S, Huikuri HV. 24-hour
       baseline heart rate dynamics predicts the response to aerobic training in sedendary subjects.
       7th Annual Congress of the European College of Sport Science, Proceedings2002; 1:O671:
       591.

125.   Hautala AJ, Kiviniemi A, Mäkikallio TH, Nissilä S, Kinnunen H, Huikuri HV, Tulppo MP.
       Differences in very-low-frequency R-R interval oscillations among athletes. 7th Annual
       Congress of the European College of Sport Science, Proceedings 2002; 1:O670: 590.

126.   Nissinen SI, Mäkikallio TH, Tapanainen JM, Tulppo MP, Huikuri HV. Heart rate recovery
       immediately after exercise as a predictor of mortality after an acute myocardial infarction.
       Eur Heart J 2002; 23:P2153.

127.   Huikuri HV, Mahaux V, Bloch-Thomsen P-E. Cardiac arrhythmias and risk stratification
       after myocardial infarction (CARISMA): Results of the Pilot study. Eur Heart J 2002;
       23:P2157.

128.   Huikuri HV, Tapanainen JM, Lindgren K, Raatikainen P, Mäkikallio TH, Myerburg RJ.
       Epidemiological pattern and prediction of sudden cardiac death after myocardial infarction
       in patients with optimized beta-blocking therapy. Eur Heart J 2002; 23:P2803.

129.   Jokinen V, Tapanainen JM, Huikuri HV. Temporal changes and prognostic significance of
       traditional and fractal measures of heart rate variability after acute myocardial infarction.
       Eur Heart J 2002; 23:P2151.

130.   Jokinen V, Tapanainen JM, Lindgren K, Mäkikallio TH, Huikuri HV. Prognostic
       significance of heart rate variability among patients with optimized beta-blocking
       medication after myocardial infarction. Eur Heart J 2002; 23:P2127.

131.   Huikuri HV, Tapanainen JM, Lindgren K, Raatikainen P, Mäkikallio TG, Airaksinen KEJ,
       Myerburg RJ. Sudden cardiac death after myocardial infarction: Prediction and temporal
       distribution of events among patients with optimized -blocking therapy. Circulation 2002;
       106:2683.

132.   Hautala AJ, tulppo MP, Mäkikallio TH, Laukkanen R, Nissilä S, Huikuri H. Effects of
       discontinuing regular aerobic training on heart rate dynamics. One year follow-up. Med Sci
       Sports Exer, Suppl, vol 34, p. 6, 2002.

133.   Tulppo MP, Shoemaker K, Tutungi E, Kimerly D, Gelb A, Hughson RL, Mäkikallio TH,
       Huikuri HV. Korkea veren noradrenaliinipitoisuus inhiboi neuraalista sympaattista
       aktiivisuutta. Liikunta & Tiede 2002;5:42.

134.   Kiviniemi A, Hautala AJ, Mäkikallio TH, Nissiliä S, Kinnunen H, Huikuri HV, Tulppo
       MP. Kestävyysharjoittelun onnistuminen on yhteydessä sydämen vagaaliseen säätelyyn.
       Liikunta & Tiede 2002;5:33.

135.   Hautala AJ, Mäkikallio TH, Laukkanen RT, Nissilä S, Huikuri HV, Tulppo MP.
       Harjoittelun vaikutukset sydämen sykevaihtelun dynamiikkaan: 12 kuukauden
       seurantatutkimus. Liikunta & Tiede 2002;5:30.
                                                                                                 37



136.   Nissinen SI, Mäkikallio TH, Seppänen T, Tapanainen JM, Salo M, Tulppo MP, Huikuri
       HV, Sykkeen palauttaminen ennustaa toipumista sydäninfarktipotilailla. Liikunta & Tiede
       2002;5:17-18.

137.   Lindgren KS, Tapanainen JM, Raatikainen PJ, Huikuri HV. Previous intense sport activity
       and ione atrial fibrillation. European Journal of Echocardiography 2002; 3:733.

138.   Kaikkonen K, Kortelainen ML, Tapanainen JM, Kakko S, Pietilä E, Savolainen M,
       Kesäniemi YA, Huikuri HV. Factor VII R353Q polymorphism and sudden cardiac death
       due to acute ischemic event. 29th Progress Report Meeting 2003.

139.   Junttila MJ, Raatikainen MJP, Perkiömäki JS, Lindgren KS, Hong K, Brugada R, Huikuri
       HV. Clustering of atrial fibrillation in Finnish families with a Brugada syndrome like
       electrocardiographic pattern. 29th Progress Report Meeting 2003.

140.   Junttila MJ, Raatikainen MJP, Perkiömäki JS, Lindgren KS, Hong K, Brugada R, Huikuri
       HV. Clustering of atrial fibrillation in Finnish families with a Brugada syndrome like
       electrocardiographic pattern. Pacing and Clinical Electrophysiology 2003;26 (Part II):23.

141.   Tapanainen JM, Lindgren KS, Mäkikallio TH, Vuolteenaho O, Leppäluoto J, Huikuri HV.
       B-type natriuretic peptide predicts sudden cardiac death after acute myocardial infarction.
       Pacing and Clinical Electrophysiology 2003;26 (Part II):287.

142.   Raatikainen P, Mahaux V, Bloch-Thomsen P-E, Huikuri HV for the CARISMA
       Investigators. Prevalence of patients with MUSTT and MADIT indications for prophylactic
       ICD treatment after myocardial infarction. Pacing and Clinical Electrophysiology 2003;26
       (Part II):235.

143.   Hautala AJ, Mäkikallio TH, Laukkanen RT, Nissilä S, Huikuri HV, Tulppo MP.
       Cardiovascular autonomic function predictd the response to aerobic training in sedentary
       subjects. Medicine&Science in Sports&Exercise 2003;35 (Suppl):1536.

144.   Kiviniemi AM,Hautala AJ, Mäkikallio TH, Nissilä S, Kinnunen H, Huikuri HV, Tulppo
       MP. Relationship between training and heart rate variability in endurance athletes.
       Medicine&Science in Sports&Exercise 2003;35 (Suppl):1540.

145.   Tulppo M, Kallio M, Hautala A, Kiviniemi A, Pietarila P, Seppänen T, Huikuri H.
       Physiological backgroud of fractal heart rate dynamics.ECSS 8th Annual Congress European
       College of Sport Science 2003:O121B-1.

146.   Kiviniemi A, Hautala A, Seppänen T, Mäkikallio T, Huikuri H, Tulppo M. Bimodal
       relationship between the heart rate and high-frequency oscillation of heart rate in athletes.
       ECSS 8th Annual Congress European College of Sport Science 2003:O121B-3.

147.   Hautala AJ, Kiviniemi A, Kinnunen H, Nissilä S, Mäkikallio TH, Huikuri HV, Tulppo MP.
       Association between training response and cardiac vagal in sedentary subjects. ECSS 8th
       Annual Congress European College of Sport Science 2003:O121BJ-5.
                                                                                               38

148.   Mäkikallio TH, Barthel P, Schneider R, Tapanainen J, Bauer A, Seppänen T, Schmidt G,
       Huikuri HV. Heart rate turbulence predicts sudden caridac death among the patients with
       preserved left ventricular function after acute myocardial infarction. Circulation, (suppl)
       2003;108:3103.

149.   Junttila MJ, Raatikainen MJP, Perkiömäki JS, Lindgren KS, Hong K, Brugada Huikuri HV.
       Clustering of atrial fibrillation in Finnish families with a Brugada syndrome like
       electrocardiographic pattern. Europace 2003;4:P-235 (B121).

150.   Junttila MJ, Raatikainen MJP, Karjalainen J, Huikuri HV. Prevalence and prognostic of
       subjects with Brugada type ecg pattern in Finnish male population. Europace 2003;4:P-319
       (B141).

151.   Mäkikallio TH, Tapanainen JM, Seppänen T, Huikuri HV. Heart rate variability, turbulence
       and dynamics as predictors of sudden cardiac death after myocardial infarction in beta-
       blocking era. Eur Heart J 2003;387:P2066.

152.   Huikuri HV, Raatikainen MJP, Mahaux V, Bloch-Thomsen P-E and for the CARISMA
       Investigators. Prevalence of patients with MUSTT and MADIT II indications for
       prophylactic ICD treatment after myocardial infarction. Europace 2003;4:P-496 (B183).

153.   Hautala AJ, Mäkikallio TH, Kiviniemi A, Laukkanen RT, Nissilä S, Huikuri HV, Tulppo
       MP. Sydämen sykevaihtelu ennustaa yksilöllistä kuntomuutosta. Liikunta ja Tiede,
       Erikoisliite 2003.

154.   Kiviniemi AM, Hautala AJ, Seppänen T, Mäkikallio TH, Huikuri HV, Tulppo MP.
       Sydämen sykkeen ja sykevaihtelun välinen yhteys urheilijoilla. Liikunta ja Tiede,
       Erikoisliite 2003.

155.   Kiviniemi AM, Hautala AJ, Mäkikallio TH, Laukkanen RT, Nissilä S, Seppänen T, Huikuri
       HV, Tulppo MP. Saturation of vagally mediated heart rate variability after aerobic
       training.Book of abstracts, 9th Annual Congress European College of Sort Science
       2004:O42Brown06.

156.   Tulppo MP, Hautala AJ, Kiviniemi AM, Kinnunen H, Nissilä S, Huikuri HV, Mäkikallio
       TH. Heart rate reserve is higher in male than female. Book of abstracts, 9th Annual Congress
       European College of Sort Science 2004:O46White01.

157.   Hautala AJ, Kiviniemi AM, Mäkikallio TH, Kinnunen H, Nissilä S, Huikuri HV, Tulppo
       MP. Gender differences in cardiovascular autonomic regulation after short-term aerobic
       training. Book of abstracts, 9th Annual Congress European College of Sort Science
       2004:O46White06.

158.   Kiviniemi AM, Hautala AJ, Mäkikallio TH, Laukkanen RT, Nissilä S, Seppänen T, Huikuri
       HV. Tulppo MP. A plateau in the raltionship between high-frequency power and R-R
       intervals at low heart rates. Medicine&Science in Sports&Exercise 2004;36 (suppl):0892.

159.   Raatikainen P, Jokinen V, Virtanen V, Hedman A, Hartikainen J, Huikuri HV. T-wave
       alternans during exercise and pacing in post-AMI patients. Europace 2004;6(suppl1):167/2.
                                                                                                   39

160.   Mäkikallio TH, Barthel P, Schneider R, Bauer A, Tapanainen JM, Schmidt G, Huikuri HV.
       Altered epidemiological pattern of sudden cardiac death in AMI survivors with optimized
       therapy. Europace 2004;6(suppl1):148/1.

161.   Perkiömäki JS, Niskasaari E, Karsikas M, Seppänen T, Huikuri HV. T-wave and QRS
       complex morphology and ventricular tachyarrhythmias. Europace 2004;6(suppl1):34/5.

162.   Mäkikallio TH, Barthel P, Scheider R, Tapanainen J, Perkiömäki J, Schmidt G, Huikuri
       HV. Altered epidemiological pattern of sudden cardiac death among myocardial infarction
       survivors with optimized medical and revascularization therapy. Heart Rhythm 2004
       (suppl);1:409.

163.   Bauer A, Kantelhardt J, Barthel P, Schneider R, Mäkikallio T, Ulm K, Bunde A, Hnatkova
       K, Huikuri HV, Mlik M, Schmidt G. Phase-rectified signal averaging is superior to lVEF in
       prediction of late mortality after acute MI. Circulation 2004;110;(17):2155.

164.   Junttila J, Raatikainen P, Lindgren KS, Perkiömäki JS, Huikuri HV. Brugada type
       electrocardiogram in lone atrial fibrillation. Circulation 2004;110;(17):3097.

165.   Kiviniemi AM, Hautala AJ, Seppänen T, Mäkikallio TH, Huikuri HV, Tulppo MP.
       Sykevaihtelun saturaatio terveillä ja sydäninfarktipotilailla. Liikunta ja Tiede, Erikoisliite
       2004.

166.   Hautala AJ, Kiviniemi AM, Mäkikallio TH, Huikuri HV, Tulppo MP. Yksilöllinen
       kuntomuutos kestävyys- ja voimaharjoittelun jälkeen: satunnaistettu kontrolloitu cross-over
       tutkimus. Liikunta ja Tiede, Erikoisliite 2004.

167.   Anttonen O, Silvola J, Kokkonen L, Brugada R, Junttila J, Hong K, Huikuri HV. A novel
       inherited syndrome of short QT interval malignant ventricular arrhythmias and familial
       clustering of otosclerosis. Heart Rhythm 2005(suppl);2:P2-118.

168.   Kiviniemi A, Tulppo MP, Hautala AJ, Mäkikallio TH, Seppänen T, Huikuri HV. A novel
       heart rate variability index of cardiac vagal outflow predicts sudden cardiac death after an
       acute myocardial infarction. Heart Rhythm 2005(suppl);2:AB27-6.

169.   Hautala AJ, Rankinen T, Kiviniemi AM, Mäkikallio TH, Kinnunen H, Nissilä S, Seppänen
       T, Huikuri HV, Tulppo MP. Increase in aerobic fitness is associated with inmproved
       cardiac autonomic regulation. The International XVIII Puijo Symposium, Kuopio, Finalnd,
       2005.

170.   Perkiömäki J, Hyytinen-Oinas M, Karsikas M, Seppänen T, Hnatkova K, Malik M, Huikuri
       HV. T-wave loop and QRS complex loop variables and mortality in postinfarction patients.
       EUROPACE 2005;7:31.

171.   Kiviniemi AM, Tulppo MP, Hautala AJ, Mäkikallio T, Seppänen T, Huikuri HV. A novel
       heart rate variability index of cardiac vagal outflow predicts sudden cardiac after an acute
       myocardial infarction. EUROPACE 2005;7:727.

172.   Messier. Lu S, Huikuri H, Bloch-Thomsen P.E., Morch R, Olesen, Stylos L, Talsma P,
       Kaiser D, on behalf of the CARISMA study team. Estimating heart rate variability using
                                                                                              40

       reveal plus EKG: validation using data collected from CARISMA. Eur Heart J 2005;26
       (suppl):P2203.

173.   Tulppo MP, Hautala AJ, Kiviniemi AM, Kinnunen H, Nissilä S, Mäkikallio TH, Huikuri
       HV. Voima- ja kestävyysharjoittelun vaikutukset verenpaineeseen. Liikunta ja Tiede,
       Erikoisliite 2004.

174.   Kiviniemi AM, Tulppo MP, Hautala AJ, Mäkikallio TH, Tiinanen S, Seppänen T, Huikuri
       HV. Uusi sykevaihtelumenetelmä ennustaa sydänperäistä äkkikuolemaa
       sydäninfarktipotilailla. XIV Liikuntalääketieteen päivät, Helsinki, 2005.

175.   Kaikkonen K, Linna E, Kortelainen M-L, Huikuri HV. Family history and the risk of
       sudden cardiac death as a manifestation of an acute ischemic event. Atherosclerosis Club
       Annual Meeting in Oulu, 2006:13.

176.   Anttonen O, Junttila J, Viitasalo M, Rissanen H, Reunanen A, Huikuri HV. Prevalence and
       prognostic significance of short QT-interval in middle-aged Finnish population. Heart
       Rhythm Society 2006;3:suppl. P1-26.

177.   Kaikkonen KS, Kortelainen M-L, Huikuri HV., Family history and the risk of sudden
       cardiac death as a manifestation of an acute ischemic event. . Heart Rhythm Society
       2006;3:suppl. P4-22.

178.   Junttila J, Anttonen O, Giustetto C, GAita F, Linna E, Karsikas M, Seppänen T, Perkiömäki
       JS, Mäkikallio TH, Brugada R, Huikuri HV. T-wave morphology in short QT-syndrome .
       Heart Rhythm Society 2006;3:suppl. P4-37.

179.   Junttila J, Raatikainen P, Lindgren KS, Perkiömäki JS, Brugada R, Huikuri HV.
       Association between Brugada type electrocardiogram and family history of lone atrial
       fibrillation. . Heart Rhythm Society 2006;3:suppl. P6-56.

180.   Huikuri HV, Peltola MA, Tulppo M, Kiviniemi A, Mäkikallio TH, Seppänen T, Barthel P,
       Schmidt G. Respiratory sinus arrhythmia as a predictor of sudden cardiac death after
       myocardial infarction. Heart Rhythm Society 2006;3:suppl. AB28-4.

181.   Bauer A, Kantelhardt JW, Barthel P, Schneider R, Mäkikallio TH, Ulm K, Hnatkova K,
       Schömig A, Huikuri HV, Bunde A, Malik M, Scmidt G. Deceleration capacity of heart rate
       as a prediction of late mortality after myocardial infarction. Heart Rhythm Society
       2006;3:suppl. YI1-4.

182.   Perkiömäki JS, Jokinen V, Tapanainen J, Huikuri HV. Autonomic markers and non-fatal
       acute coronary events in postinfarction patients. Eur Heart J 2006;27:843.

183.   Perkiömäki JS, Jokinen V, Tapanainen J, Huikuri HV. Autonomic markers and non-fatal
       acute coronary events in postinfarction patients. Europace 2006;8:235/4

184.   Perkiömäki JS, Jokinen V, Tapanainen J, Huikuri HV. Autnomic markers as predictors on
       non-fatal acute coronary events after myocardial infarction. JACC 2006;47:Suppl A:998-
       246.
                                                                                            41

185.   Perkiömäki J, Jokinen V, Tapanainen J, Huikuri H. Outcomes after ACS and PCI. JACC
       2006;suppl.:47:216A.

186.   Tulppo MP, Kiviniemi A, Hautala A, Kallio M, Tiinanen S, Seppänen T, Huikuri H:
       Association between heart rate recovery and sympathetic outflow. 8th Scandinavian
       Congress of Medicine and Science in Sports (SCMSS), Vierumäki, Finland, 2006. book of
       Abstracts, page 95.

187.   Hautala A, Kiviniemi A, Mäkikallio T, Tiinanen S, Seppänen T, Huikuri H, Tulppo MP:
       Relationship between sympathetic outflow and physical performance. 8th Scandinavian
       Congress of Medicine and Science in Sports (SCMSS), Vierumäki, Finland, 2006. book of
       Abstracts, page 27.

188.   Kiviniemi AM, Huikuri HV, Hautala AJ, Tiinanen S, Seppänen T, Mäkikallio TH, Tulppo
       MP. Changes in fluctuation pattern of cardiovascular signals during sympathetic activation.
       11th European Collage of Sport Science (ECSS) annual meeting, Lausanne, Switzerland
       2006. Book of Abstracts p.301

189.   Hautala AJ, Kiviniemi AM, Mäkikallio TH, Tiinanen S, Seppänen T, Huikuri HV, Tulppo
       MP. Peripheral sympathetic outflow correlates with the response to endurance training. 11th
       European Collage of Sport Science (ECSS) annual meeting, Lausanne, Switzerland 2006.
       Book of Abstracts p.304

190.   Hautala AJ, Rankinen T, Kiviniemi AM, Mäkikallio TH, Huikuri HV, Bouchard C, Tulppo
       MP. Heart Rate Recovery after Maximal Exercise Is Associated with Acetylcholine
       Receptor M2 (CHRM2) Gene Polymorphism. ACSM annual meeting 2006. Med Sci Sports
       Exer. Suppl, vol 38, p. 49, 2006..

191.   Tulppo MP, Kiviniemi AM, Hautala AJ, Mäkikallio TH, Tiinanen S, Seppänen T, Huikuri
       HV. Association between baroreflex sensitivity and aerobic fitness after dynamic exercise.
       ACSM annual meeting 2006. Med Sci Sports Exer. Suppl, vol 38, p. 18, 2006.

192.   Tulppo MP, Kiviniemi A, Hautala A, Kallio M, Tiinanen S, Seppänen T, Huikuri H:
       Sydämen sykkeen palautuminen on yhteydessä sympaattiseen aktiivisuuteen. 8th
       Scandinavian Congress of Medicine and Science in Sports (SCMSS), Vierumäki, Finland,
       2006. Liikunta ja tiede 43, 5, 2006, sivu 43.

193.   Hookana E, Junttila JM, Särkioja T, Niemelä M, Raatikainen P, Peuhkurinen K, Brugada R,
       Huikuri HV. Sudden cardiac deat and left ventricular fibrosis in a Finnish family with
       mutation R541C in the lamin A/C gene. 33rd Progress Report Meeting, January 26, 2007.

				
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