Sup-table-2

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					                                                                                         Cleava
                                                                         Seq size          ge
                                                            Link to        (aa     SigP Positi                   Matur
               Seq name              Link to nucleotide      NCBI       residues) Result   on     MW      pI     e MW
Group 1: Basic Tail Peptides
IS-18-24-clu17putative              IS-18-24-clu17putative 67083136       121      SIG   21-22    13.62   8.99   11.32
ISNU-L-ISN-1                        ISNU-L-ISN-1             67083694     121      SIG   21-22    13.34    8.9   11.12
gi|22164156                         gi|22164155              22164156     121      SIG   21-22    13.56   8.67   11.3
ISNU-L-ISN-4                        ISNU-L-ISN-4             67083733     125      SIG   21-22    13.86   8.82   11.6
gi|22164188                         gi|22164187              22164188     120      SIG   21-22    13.29   9.27   11.04
gi|22164174                         gi|22164173              22164174     125      SIG   21-22    13.87   9.25   11.61
ISN-L-15                                                     67083505
                                    ISN-L-is_5_100_92_15_CLUputative      125      SIG   21-22    13.89   8.96   11.63
IS-18-24-clu18b                     IS-18-24-clu18b          67083142     121      SIG   21-22    13.47   9.17   11.21
ISN-L-16                            ISN-L-is_5_100_92_16_CLU 67083509     120      SIG   21-22    13.33   9.15   11.07
gi|22164184                         gi|22164183              22164184     121      SIG   21-22    13.51   8.83   11.23
IS-18-24-clu18a                     IS-18-24-clu18a          67083140     120      SIG   21-22    13.39   9.07   11.13
IS-18-24-Clu16                      IS-18-24-Clu16           67083134     121      SIG   21-22    13.41   8.83   11.18
ISNU-L-ISN-2                        ISNU-L-ISN-2             67083723     121      SIG   21-22    13.59   8.83   11.31
gi|22164176                         gi|22164175              22164176     121      SIG   21-22    13.39   8.89   11.13
gi|55736023                         gi|55736022              55736023     125      SIG   21-22    13.72   8.82   11.45
IS-6-12L-5-100-92-5                 IS-6-12L-5-100-92-5                   121      SIG   21-22    13.42   8.97   11.17
gi|22164186                         gi|22164185              22164186     121      SIG   21-22    13.5    9.11   11.24
IS-18-24-clu21putative              IS-18-24-clu21putative 67083154       121      SIG   21-22    13.43   8.68   11.17
gi|22164164                         gi|22164163              22164164     121      SIG   21-22    13.43   8.89   11.14
gi|15428308                         gi|15428307              15428308     125      SIG   21-22     14     8.87   11.7
gi|22164192                         gi|22164191              22164192     126      SIG   22-23    14.03   9.14   11.7
gi|22164154                         gi|22164153              22164154     122      SIG   21-22    13.65   9.11   11.33
gi|22164180                         gi|22164179              22164180     122      SIG   21-22    13.67     9    11.33
gi|22164166                         gi|22164165              22164166     122      SIG   21-22    13.66   9.11   11.34
is-all-15                           is-all-15                67083397     121      SIG   21-22    13.55   8.86   11.24
gi|22164160                         gi|22164159              22164160     122      SIG   21-22    13.74   9.14   11.37
ISNU-L-ISN-22                       ISNU-L-ISN-22            67083727     121      SIG   21-22    13.56   8.99   11.23
gi|22164162                         gi|22164161              22164162     122      SIG   21-22    13.72   8.86   11.38
is-all-10                           is-all-10                67083393     121      SIG   21-22    13.55   9.05   11.34
gi|22164172                         gi|22164171              22164172     122      SIG   21-22    13.74   9.15   11.36
gi|22164168                         gi|22164167              22164168     122      SIG   21-22    13.61   9.11   11.33
gi|22164170                         gi|22164169              22164170     122      SIG   21-22    13.63   9.11   11.31
ISN-L-11                                                     67083497
                                    ISN-L-is_5_100_92_11_CLUputative      121      SIG   21-22    13.56   9.11   11.2
IS-6-12L-18                         IS-6-12L-18              67083353     121      SIG   21-22    13.46   8.94   11.24
gi|22164182                         gi|22164181              22164182     122      SIG   21-22    13.72   9.14   11.33
gi|22164178                         gi|22164177              22164178     122      SIG   21-22    13.65     9    11.3
ISJ-ISPL_P9_D8                      ISJ-ISPL_P9_D8           67083481     127      SIG   21-22    14.28    7.5   11.86
ISNU-L-ISN-3                        ISNU-L-ISN-3             67083729     155      SIG   16-17    17.71     9    15.63
ISNU-cluster-89                     ISNU-cluster-90          67083688     130      SIG   21-22    14.71   8.88   12.19
ISNU-cluster-89a                    ISNU-cluster-89aputative 67083690     166      SIG   21-22    18.73   9.43   16.24
IS-18-24-clu384                     IS-18-24-clu384          67083180     118      SIG   21-22    13.06   4.78   10.59
gi|22164194                         gi|22164193              22164194     120      SIG   21-22    13.34   7.56   11.12
Group 2: Basic Tail-less Peptides
gi|22164158                         gi|22164157            22164158       102      SIG   21-22 11.44       4.2   9.086
gi|22164152                         gi|22164151            22164152       96       SIG   15-16 10.74      4.23   9.025
gi|33340608                           gi|22164151             22652868   91    SIG   21-22   10.1    4.34   7.723
ISNU-L-ISN-6                          ISNU-L-ISN-6            67083745   91    SIG   21-22   10.13   4.22   7.779
ISNU-L-ISN-6a                         ISNU-L-ISN-6a           67083751   91    SIG   21-22   10.18   4.21   7.837
ISNU-L-ISN-7                          ISNU-L-ISN-7            67083753   91    SIG   21-22   10.01   4.29   7.669
ISNU-L-ISN-10                         ISNU-L-ISN-10           67083696   91    SIG   21-22   10.05   4.42   7.709
ISNU-L-ISN-12                         ISNU-L-ISN-12           67083701   91    SIG   21-22   10.13   4.22   7.71
ISNU-L-ISN-9                          ISNU-L-ISN-9            67083765   91    SIG   21-22   10.07   4.29   7.68
is-all-17                             is-all-17               67083401   91    SIG   21-22   10.07   4.29   7.693
ISNU-L-ISN-11                         ISNU-L-ISN-11           67083699   91    SIG   21-22   10.09   4.17   7.693
IS-6-12-J-cluster-394                 IS-6-12-J-cluster-394   67083272   62    SIG   19-20   7.106   8.73   4.684
gi|22164190                           gi|22164189             22164190   101   SIG   21-22   11.17   4.58   8.858
Group 3: Kunitz containing proteins
Single Kunitz - Monolaris
IS-6-12L-5-58                         IS-6-12L-5-58         67083381     96    SIG   17-18   10.64   5.46   8.722
gi|22164254                           gi|22164253           22164254     96    SIG   17-18   10.18   8.18   8.253
gi|22164252                           gi|22164251           22164252     96    SIG   17-18   10.21   8.18   8.253
gi|15428348                           gi|15428347           15428348     96    SIG   17-18   10.42   8.17   8.473
gi|22164248                           gi|22164247           22164248     91    SIG   17-18   9.898   7.52   7.922
ISN-L-87                                                    67083583
                                      ISN-L-is_5_100_92_87_CLU           91    SIG   24-25    9.9    8.52   7.171
gi|22164250                           gi|22164249           22164250     91    SIG   24-25   9.87    8.52   7.143
gi|55736019                           gi|55736018           55736019     96    SIG   17-18   10.49   8.17   8.506
gi|22164258                           gi|22164257           22164258     96    SIG   17-18   10.43   8.48   8.462
gi|22164260                           gi|22164259           22164260     96    SIG   17-18   10.48   8.48   8.462
gi|22164246                           gi|22164245           22164246     91    SIG   17-18   9.883   7.52   7.906
ISN-L-29                                                    67083533
                                      ISN-L-is_5_100_92_29_CLU           96    SIG   17-18   10.53   8.88   8.561
ISNU-L-ISN-143                        ISNU-L-ISN-143        67083711     82    SIG   19-20   9.205   9.23   7.027
gi|22164286                           gi|22164285           22164286     82    SIG   23-24   8.975   9.64   6.301
IS-18-24-clu265                       IS-18-24-clu265       67083162     92    SIG   19-20   10.1    5.57   7.989
ISJ-ISPL_P8_C1                        ISJ-ISPL_P8_C1        67083475     87    SIG   19-20   9.344   5.79   7.189
gi|22164218                           gi|22164217           22164218     92    SIG   19-20   10.27   6.69   8.02
gi|22164198                           gi|22164197           22164198     81    SIG   19-20   8.668   8.79   6.616
ISN-L-53A                                                   67083559
                                      ISN-L-is_5_100_92_53A_CLU          78    SIG   19-20   8.627   5.25   6.515
ISNU-cluster-414                      ISNU-cluster-414      67083657     78    SIG   21-22   8.561    5.7   6.203
ISJ-ISPM_P1_A11                       ISJ-ISPM_P1_A11       67083489     94    SIG   19-20   10.45   8.35   8.289
gi|22164214                           gi|22164213           22164214     94    SIG   19-20   9.944   8.62   7.893
gi|22164216                           gi|22164215           22164216     95    SIG   19-20   10.21   8.91   8.074
ISN-L-91                                                    67083593
                                      ISN-L-is_5_100_92_91_CLU           95    SIG   19-20   10.27   8.76   8.088
ISN-L-59                                                    67083563
                                      ISN-L-is_5_100_92_59_CLU           85    SIG   21-22   9.084   5.16   6.709
ISJ-ISPL_P5_A8                        ISJ-ISPL_P5_A8        67083441     82    SIG   19-20   8.732   6.51    6.6
IS-6-12L-4                            IS-6-12L-4            67083359     85    SIG   27-28   8.963   4.85   5.946
gi|22164212                           gi|22164211           22164212     85    SIG   27-28   9.188   4.69   6.19
IS-6-12L-4B                           IS-6-12L-4B           67083365     85    SIG   19-20   9.146   4.54   6.99
ISJ-ISPL_P5_H8                        ISJ-ISPL_P5_H8        67083447     86    SIG   19-20   9.365    5.1   7.225
ISN-L149                              ISN-L149              67083503     85    SIG   23-24   9.469   6.06   6.673
ISN-L-67                                                    67083569
                                      ISN-L-is_5_100_92_67_CLU           84    SIG   19-20   9.16    4.97   7.025
gi|22164204                           gi|22164203           22164204     85    SIG   19-20   9.052   6.51   6.921
IS-18-24-clu2                         IS-18-24-clu2         67083150     85    SIG   21-22   9.026   5.63   6.65
ISN-L-46                                                    67083549
                                      ISN-L-is_5_100_92_46_CLU           106   SIG   19-20   11.17   7.49   9.027
ISN-L-53                                                    67083557
                                      ISN-L-is_5_100_92_53_CLU           84    SIG   19-20   9.315   4.64   7.106
gi|22164208                           gi|22164207           22164208     84    SIG   19-20   9.077   4.86   6.936
gi|22164210                           gi|22164209           22164210     84    SIG   19-20   9.161   8.92   7.032
ISN-L-62                                                    67083565
                                      ISN-L-is_5_100_92_62_CLU           91    SIG   18-19   10.31    9.1   8.122
ISNU-cluster-522                      ISNU-cluster-522      67083678     91    SIG   18-19   10.36   9.08   8.232
gi|22164308                           gi|22164307           22164308     91    SIG   18-19   10.33   9.12   8.155
ISN-L-154                                                   67083507
                                      ISN-L-is_5_100_92_154_CLU          97    SIG   17-18   10.52   6.69   8.532
ISJ-ISPL_P6_B2                        ISJ-ISPL_P6_B2        67083449     99    SIG   17-18   10.95   8.92   9.03
IS-6-12L-81                           IS-6-12L-81           67083387     97    SIG   17-18   10.45   6.52   8.467
ISN-L-75                                                    67083577
                                      ISN-L-is_5_100_92_75_CLUPutative   94    SIG   19-20   10.39   8.52   8.152
gi|22164220                           gi|22164219           22164220     94    SIG   19-20   10.4    8.53   8.18
gi|22164196                           gi|22164195           22164196     75    SIG   19-20   8.468   8.82   6.244
IS-6-12L-86                           IS-6-12L-86           67083389     94    SIG   16-17   10.48   7.65   8.526
IS-18-24-clu42                        IS-18-24-clu42        67083186     94    SIG   16-17   10.46   7.65   8.53
gi|56159935                           gi|56159934           56159935     94    SIG   16-17   10.53   7.65   8.576
ISNU-L-ISN-125                              ISNU-L-ISN-125         67083705     91    SIG   19-20   10.22     9     7.995
gi|22164206                                 gi|22164205            22164206     81    SIG   19-20   9.022   8.68    6.838
gi|22164200                                 gi|22164199            22164200     81    SIG   21-22   8.795   4.91    6.446
gi|22164202                                 gi|22164201            22164202     82    SIG   19-20   8.924   5.22    6.831
ISN-L341                                    ISN-L341               67083539     96    SIG   17-18   10.6    8.73    8.562
ISNU-L-ISN-79                               ISNU-L-ISN-79          67083761     94    SIG   19-20   10.26   8.14    8.049
ISUFJ-cluster-367                           ISUFJ-cluster-367      67083779     96    SIG   19-20   11.06   9.25    8.724
IS-18-24-clu519                             IS-18-24-clu519        67083198     71    SIG   18-19   7.958   7.47    5.695
gi|56159965                                 gi|56159964            56159965     95    SIG   28-29   10.54   8.95    7.381
gi|22164256                                 gi|22164255            22164256     97    SIG   22-23   10.44   8.17    7.893
Bilaris/Ixolaris - double Kunitz proteins
ISN-L709                                    ISN-L709                67083575    137   SIG   20-21   15.9    9.06    13.53
ISJ-ISPL_P6_C11putative                     ISJ-ISPL_P6_C11putative             154   SIG   19-20   17.29   8.02    15.13
ISN-L-131                                                           67083501
                                            ISN-L-is_5_100_92_131_CLU           168   SIG   31-32   18.75   4.65    15.18
gi|15077002                                 gi|15077001             15077002    165   SIG   26-27   18.41   4.63    15.4
gi|22164284                                 gi|22164283             22164284    174   SIG   26-27   18.73   5.78    15.87
ISNU-cluster-257                            ISNU-cluster-257        67083629    176   SIG   18-19   19.56     9     17.34
ISNU-cluster-402                            ISNU-cluster-402        67083655    175   SIG   18-19   20.09   8.42    17.89
IS-18-24-clu90                              IS-18-24-clu90          67083208    178   SIG   18-19   20.38   8.83    18.21
IS-6-12-J-IS612-186                         IS-6-12-J-IS612-186     67083327    187   SIG   21-22   21.07   8.96    18.53
IS-6-12-J-IS612-151secreted                                         67083325
                                            IS-6-12-J-IS612-151secreted         190   SIG   18-19   21.32   9.06    19.09
ISNU-cluster-484                            ISNU-cluster-484        67083667    206   SIG   17-18   24.2    7.82    22.22
Penthalaris - Five Kunitz domains
ISNU-cluster-435                            ISNU-cluster-435       67083661     258   SIG   19-20   29.12   5.44    26.74
ISJ-ISPL_P5_F10                             ISJ-ISPL_P5_F10        67083443     293   SIG   21-22   33.64   5.36    30.98
ISNU-cluster-105                            ISNU-cluster-105       67083601     320   SIG   19-20   36.11   7.27    33.88
ISJ-ISPL_P6_F12                             ISJ-ISPL_P6_F12        67083461     324   SIG   17-18   36.52   8.76    34.67
ISNU-cluster-203                            ISNU-cluster-203       67083615     330   SIG   19-20   37.95   8.76    35.62
gi|22164266                                 gi|22164265            22164266     330   SIG   22-23   38.05   8.56    35.28
gi|22164262                                 gi|22164261            22164262     319   SIG   19-20   35.71   8.31    33.5
gi|22164264                                 gi|22164263            22164264     321   SIG   19-20   36.38   8.41    34.02
Group 4: Pro-Gly Rich
ISUFJ-cluster-287                           ISUFJ-cluster-287        67083773   96    SIG   19-20   9.922   7.95     7.7
ISNU-cluster-376                            ISNU-cluster-376         67083647   67    SIG   19-20   6.68    9.06    4.474
ISNU-cluster-253                            ISNU-cluster-253         67083625   64    SIG   19-20   6.322    6.5    4.14
ISN-L-5                                                              67083551
                                            ISN-L-is_5_100_92_5_CLUputative     65    SIG   19-20   6.435   6.51    4.234
ISN-L346                                    ISN-L346                 67083541   66    SIG   20-21   6.664   7.87    4.278
ISN-L-3                                     ISN-L-is_5_100_92_3_CLU  67083535   65    SIG   19-20   6.528   7.75    4.363
ISN-L-1D                                                             67083525
                                            ISN-L-is_5_100_92_1D_CLUputative    64    SIG   19-20   6.426   7.75    4.262
ISN-L-1C                                                             67083523
                                            ISN-L-is_5_100_92_1C_CLUputative    65    SIG   19-20   6.305   5.87    4.169
ISN-L-1B                                                             67083521
                                            ISN-L-is_5_100_92_1Bputative        67    SIG   19-20   6.657   9.06    4.488
ISN-L-1                                     ISN-L-is_5_100_92_1_CLU  67083493   65    SIG   19-20   6.337   7.74    4.173
is-all-636                                  is-all-636               67083423   81    SIG   17-18   8.025   5.29    5.964
IS-6-12L-93                                 IS-6-12L-93              67083391   64    SIG   19-20   6.23    7.69    4.04
IS-6-12L-54                                 IS-6-12L-54              67083379   65    SIG   19-20   6.373   9.15    4.203
IS-6-12L-53                                 IS-6-12L-53              67083375   65    SIG   19-20   6.381   8.66    4.21
IS-6-12L-5-100-92-2-CLU                     IS-6-12L-5-100-92-2-CLU67083369     72    SIG   19-20   6.958   7.81    4.764
IS-6-12L-5-100-92-1-CLU                     IS-6-12L-5-100-92-1-CLU67083367     74    SIG   24-25   7.039   5.55    4.383
IS-6-12L-49                                 IS-6-12L-49              67083363   64    SIG   19-20   6.236   7.73    4.063
IS-6-12L-48                                 IS-6-12L-48              67083361   86    SIG   19-20   8.886    8.9    6.668
IS-6-12L-15                                 IS-6-12L-15              67083351   64    SIG   19-20   6.447   6.51    4.232
IS-6-12L-12A                                IS-6-12L-12A             67083349   64    SIG   19-20   6.272   5.98    4.107
IS-6-12L-12                                 IS-6-12L-12              67083347   65    SIG   19-20   6.354   7.74    4.172
IS-6-12L-10                                 IS-6-12L-10              67083343   84    SIG   19-20   8.325    5.6    6.172
IS-6-12-J-cluster-584                       IS-6-12-J-cluster-584    67083301   110   SIG   23-24   12.27   10.41   9.53
IS-6-12-J-cluster-317                       IS-6-12-J-cluster-317    67083256   86    SIG   19-20   8.798   8.37    6.534
IS-6-12-J-cluster-307                                                67083252
                                            IS-6-12-J-cluster-307putative       100   SIG   19-20   10.22   8.95    8.035
IS-6-12-J-cluster-3                         IS-6-12-J-cluster-3      67083250   62    SIG   24-25   5.838   5.48    3.185
IS-6-12-J-cluster-289                       IS-6-12-J-cluster-289    67083244   65    SIG   19-20   6.605   7.75    4.42
IS-6-12-J-cluster-108                       IS-6-12-J-cluster-108    67083216   70    SIG   19-20   6.704   4.97    4.621
IS-6-12-J-cluster-101                       IS-6-12-J-cluster-101    67083212   81    SIG   17-18   8.01    5.01    5.938
IS-18-24-clu8a                              IS-18-24-clu8a           67083206   65    SIG   19-20   6.489   6.51    4.289
IS-18-24-clu86                  IS-18-24-clu86putative   67083204   75    SIG   19-20   8.096   9.07    5.823
IS-18-24-clu8                   IS-18-24-clu8            67083202   65    SIG   19-20   6.453   6.51    4.289
IS-18-24-clu7a                  IS-18-24-clu7a           67083200   65    SIG   19-20   6.372   8.63    4.158
IS-18-24-clu217                 IS-18-24-clu217          67083152   90    SIG   23-24   8.628   11.26   5.988
IS-18-24-clu14                  IS-18-24-clu14           67083126   43    SIG   19-20   4.267   7.85    2.076
IS-18-24-clu11                  IS-18-24-clu15           67083120   65    SIG   19-20   6.525   7.75    4.32
IS-18-24-clu10                  IS-18-24-clu10           67083114   64    SIG   19-20   6.301   5.46    4.13
gi|22164244                     gi|22164243              22164244   67    SIG   19-20   6.773    9.5    4.606
gi|22164242                     gi|22164241              22164242   67    SIG   19-20   6.671    9.1    4.506
gi|22164240                     gi|22164239              22164240   65    SIG   19-20   6.571   7.75    4.336
gi|22164238                     gi|22164237              22164238   65    SIG   19-20   6.567   7.77    4.369
gi|22164236                     gi|22164235              22164236   65    SIG   19-20   6.574   8.66    4.368
gi|22164234                     gi|22164233              22164234   65    SIG   19-20   6.534   6.51    4.364
gi|22164232                     gi|22164231              22164232   65    SIG   19-20   6.517    9.1    4.377
gi|22164230                     gi|22164229              22164230   65    SIG   19-20   6.385   7.72    4.231
gi|22164228                     gi|22164227              22164228   65    SIG   19-20   6.302    6.5    4.172
gi|22164226                     gi|22164225              22164226   65    SIG   19-20   6.345   7.72    4.191
gi|22164224                     gi|22164223              22164224   65    SIG   19-20   6.339   7.77    4.175
gi|22164222                     gi|22164221              22164222   54    SIG   19-20   5.449   5.43    3.25
Group 5: 18.7 kDa family
IS-18-24-clu37putative          IS-18-24-clu37putative              178   SIG   18-19   20.25   4.91    17.9
is-all-328                      is-all-328               67083405   178   SIG   20-21   19.95   4.71    17.59
IS-6-12-J-cluster-88            IS-6-12-J-cluster-88     67083315   177   SIG   19-20    20      5.4    17.85
IS-6-12-J-cluster-14            IS-6-12-J-cluster-14     67083222   178   SIG   19-20   19.95   4.98    17.69
IS-6-12-J-cluster-26            IS-6-12-J-cluster-26     67083238   178   SIG   18-19   20.17   4.81    17.85
gi|22164316                     gi|22164315              22164316   186   SIG   20-21   20.77   5.15    18.54
Group 6: 5.3 kDa family
ISN-L175                        ISN-L175                67083513    66    SIG   22-23   7.504   9.43    4.801
ISNU-cluster-297                ISNU-cluster-297        67083635    65    SIG   22-23   7.44    8.54    4.759
ISN-L-92                        ISN-L-is_5_100_92_92_CLU67083595    67    SIG   29-30   7.535   8.93    4.214
ISNU-L-ISNU-171                 ISNU-L-ISNU-171         67083767    68    SIG   22-23   8.128   9.06    5.345
ISN-L520                        ISN-L520                67083555    65    SIG   22-23   7.601   9.16    4.845
ISN-L409                        ISN-L409                67083543    66    SIG   22-23   7.396   8.83    4.731
IS-6-12-J-cluster-308           IS-6-12-J-cluster-308   67083254    67    SIG   24-25   7.46    7.51    4.575
is-all-122                      is-all-122              67083395    65    SIG   22-23   7.468   8.86    4.734
ISNU-L-ISN-126                  ISNU-L-ISN-126putative 67083707     65    SIG   22-23   7.377   9.08    4.66
IS-6-12-J-cluster-281           IS-6-12-J-cluster-281   67083242    70    SIG   26-27   7.535   8.61    4.619
gi|22164302                     gi|22164301             22164302    69    SIG   22-23   7.823   8.57    5.098
ISNU-L-ISN-152                  ISNU-L-ISN-152          67083715    69    SIG   22-23   7.889   8.26    5.114
is-all-332                      is-all-332              67083409    69    SIG   35-36   7.597   8.86    3.585
ISNU-L-ISN-3A                   ISNU-L-ISN-3A           67083731    69    SIG   16-17   7.846   8.92    5.755
ISN-L-76                        ISN-L-is_5_100_92_76_CLU67083579    66    SIG   22-23   7.345   8.83    4.684
IS-18-24-clu413                 IS-18-24-clu493putative 67083184    67    SIG   23-24   7.431   8.96    4.647
ISJ-ISPL_P10_A2                 ISJ-ISPL_P10_A2         67083429    66    SIG   22-23   7.381   9.14    4.704
Group 7: 9.3 and 7 kDa family
ISNU-L-ISN-82                   ISNU-L-ISN-82            67083763   79    SIG   16-17   8.865   5.16    6.777
ISNU-cluster-449                ISNU-cluster-449         67083663   120   SIG   23-24   13.7    7.43    10.81
ISNU-cluster-243                ISNU-cluster-243         67083621   79    SIG   16-17   9.005   5.64    7.073
ISNU-cluster-189                ISNU-cluster-189         67083613   101   SIG   21-22   11.47   8.87    9.064
ISN-L5-100-92-24-CLU            ISN-L5-100-92-24-CLU 67083553       101   SIG   20-21   11.38   8.44    9.153
ISN-L-42                        ISN-L-is_5_100_92_42_CLU 67083545   79    SIG   16-17   8.958   5.68    7.06
ISN-L-25                        ISN-L-is_5_100_92_25_CLU 67083531   101   SIG   20-21   11.62   8.14    9.371
ISJ-ISPL_P6_G2                  ISJ-ISPL_P6_G2           67083463   79    SIG   18-19   8.801   7.58    6.653
IS-18-24-clu196b                IS-18-24-clu196bputative 67083148   111   SIG   23-24   12.15   8.07    9.457
IS-18-24-clu196                 IS-18-24-clu196          67083146   105   SIG   23-24   11.38   6.07    8.694
gi|56159941                     gi|56159940              56159941   120   SIG   23-24   13.72   7.46    10.84
gi|22164310                     gi|22164309              22164310   101   SIG   20-21   11.46   8.14    9.232
gi|22164306                     gi|22164305              22164306   79    SIG   16-17   8.88    6.12      7
Group 8: Metalloproteases
gi|22164296                     gi|22164295              22164296   403   CYT         46.12     8.68
gi|60729624                     gi|31322779              31322780   488   IND         55.75     6.96
gi|31322780                     gi|31322779              31322780   488   SIG   19-20 55.75     6.96    53.44
gi|22164294                              gi|22164293              22164294   367   CYT           42.25   8.72
Group 9: Ixodegrin, RGD containing peptides
IS-18-24-clu190                          IS-18-24-clu190          67083144   60    SIG   21-22   6.527   4.66   4.136
IS-6-12L-11                              IS-6-12L-11              67083345   60    SIG   21-22   6.583   4.66   4.102
IS-18-24-clu189                          IS-18-24-clu189          67083138   61    SIG   21-22   6.627   4.44   4.214
ISNU-cluster-288                         ISNU-cluster-288         67083633   110   SIG   21-22   11.45   3.68   9.02
is-all-162                               is-all-162               67083399
is-all-979                               is-all-979               67083427
IS-18-24-clu45                           IS-18-24-clu45           67083190   111   SIG   21-22 11.63     3.93   9.191
is-all-306                               is-all-306               67083403
Group 10: Cys rich Ixostatins
ISUFJ-cluster-644                        ISUFJ-cluster-644putative67083781   101   SIG   18-19   10.71   8.78   8.793
ISNU-L-ISN-67                            ISNU-L-ISN-67            67083747   148   SIG   37-38   16.25   6.55   11.9
ISNU-cluster-518                         ISNU-cluster-518putative 67083673   119   SIG   24-25   12.78   8.37   10.08
ISNU-cluster-340                         ISNU-cluster-340         67083643   121   SIG   15-16   13.81   6.88   11.85
ISNU-cluster-310                         ISNU-cluster-310         67083639   141   SIG   38-39   15.84   8.96   11.34
ISNU-cluster-218                         ISNU-cluster-218         67083617   98    SIG   22-23   10.86    9.6   8.128
ISNU-cluster-155                         ISNU-cluster-155         67083607   140   SIG   37-38   15.66   8.02   11.31
ISNU-cluster-154                         ISNU-cluster-154         67083605   82    SIG   37-38   9.017   8.37   4.747
ISN-L-ISL1179                            ISN-L-ISL1179            67083597   126   SIG   19-20   13.87   9.05   11.73
ISN-L-872                                ISN-L-is_5_100_92_872_CLU67083585   114   SIG   15-16   12.89   5.91   10.9
ISN-L-650                                                         67083567
                                         ISN-L-is_5_100_92_650_CLUputative   116   SIG   19-20   12.81   5.73   10.41
ISN-L-218-B                              ISN-L-is_5_100_92_218-B  67083529   114   SIG   21-22   13.03   6.16   10.39
ISN-L-217A                               ISN-L-is_5_100_92_217A67083527      114   SIG   23-24   12.85   6.18   10.09
ISJ-ISPM_P1_D7                           ISJ-ISPM_P1_D7           67083491   125   SIG   15-16   14.43    9.2   12.58
ISJ-ISPL_P8_D5                           ISJ-ISPL_P8_D5           67083479   114   SIG   17-18   12.76    4.8   10.61
ISJ-ISPL_P6_B5                           ISJ-ISPL_P6_B5           67083451   111   SIG   22-23   12.48   8.96   9.924
is-all-585                               is-all-585               67083421   114   SIG   23-24   12.84   5.72   10.06
is-all-523                               is-all-523               67083419   116   SIG   16-17   13.18   6.39   11.11
is-all-407                               is-all-407               67083413   107   SIG   23-24   11.54   8.14   8.988
IS-6-12L-6                               IS-6-12L-6               67083383   140   SIG   39-40   15.39   7.56   10.96
IS-6-12L-5-100-92-7                                               67083373
                                         IS-6-12L-5-100-92-7putative         137   SIG   32-33   15.49   8.78   11.56
IS-6-12-J-IS612-375                      IS-6-12-J-IS612-375      67083331   137   SIG   18-19   15.06   8.56   12.83
IS-6-12-J-cluster-8                      IS-6-12-J-cluster-8      67083313   132   SIG   37-38   14.44   8.55   10.12
IS-6-12-J-cluster-56                     IS-6-12-J-cluster-56     67083299   120   SIG   22-23   13.06   7.47   10.44
IS-6-12-J-cluster-55                     IS-6-12-J-cluster-55     67083297   120   SIG   22-23   13.11   6.68   10.5
IS-18-24-clu445                          IS-18-24-clu445          67083188   118   SIG   17-18   13.06   8.63   11.16
IS-18-24-clu396                          IS-18-24-clu396          67083182   112   SIG   21-22   12.28   5.24   9.703
IS-18-24-clu35                           IS-18-24-clu35           67083172   126   SIG   19-20   13.89   8.04   11.6
IS-18-24-clu140                          IS-18-24-clu140          67083128   106   SIG   18-19   11.44   7.99   9.319
IS-18-24-clu122                          IS-18-24-clu122          67083122   117   SIG   17-18   13.47    6.4   11.21
gi|56159939                              gi|56159938              56159939   112   SIG   22-23   11.91   8.56   9.313
gi|56159923                              gi|56159922              56159923   117   SIG   33-34   12.85   8.69   8.992
gi|56159921                              gi|56159920              56159921   127   BL    21-22   14.19   8.07   11.51
gi|22164274                              gi|22164273              22164274   121   SIG   18-19   13.57    6.7   11.35
gi|22164272                              gi|22164271              22164272   114   SIG   23-24   12.86   5.85   10.06
gi|15428296                              gi|15428295              15428296   144   SIG   38-39   16.03   8.04   11.7
gi|15428294                              gi|15428293              15428294   135   SIG   21-22   14.69   8.62   12.24
gi|15428290                              gi|15428289              15428290   114   SIG   21-22   12.7    6.25   10.1
Group 11: Lipocalins
ISNU-L-ISNU-361                          ISNU-L-ISNU-361          67083769   176   SIG   19-20   20.71   5.71   18.31
ISNU-L-ISN-74                            ISNU-L-ISN-74            67083755   191   SIG   24-25   21.82   8.95   19.05
ISNU-L-ISN-68                            ISNU-L-ISN-68            67083749   220   SIG   18-19   25.61   9.08   23.44
ISNU-L-ISN-58                            ISNU-L-ISN-58            67083743   217   SIG   22-23   24.34   5.33   21.82
ISNU-L-ISN-56                            ISNU-L-ISN-56            67083741   226   SIG   16-17   25.71   4.88   23.8
ISNU-L-ISN-48                            ISNU-L-ISN-48            67083737   216   SIG   20-21   24.85   9.02   22.58
ISNU-L-ISN-47                            ISNU-L-ISN-47            67083735   189   SIG   23-24   21.62   6.14   18.88
ISNU-L-ISN-20                            ISNU-L-ISN-20            67083725   216   SIG   20-21   25.1    8.43   22.87
ISNU-L-ISN-18                            ISNU-L-ISN-18            67083721   230   SIG   20-21   26.6    8.42   24.29
ISNU-L-ISN-17                            ISNU-L-ISN-17            67083719   230   SIG   20-21   26.75   9.04   24.45
ISNU-L-ISN-16                            ISNU-cluster-19          67083717   222   SIG   20-21   25.52   8.92   23.21
ISNU-L-ISN-148                           ISNU-L-ISN-148           67083713   253   CYT           28.59    4.8
ISNU-L-ISN-130                          ISNU-L-ISN-130         67083709   222   SIG   22-23   24.85   6.15   22.38
ISNU-cluster-60                         ISNU-cluster-60        67083686   243   SIG   20-21   27.94   7.46   25.57
ISNU-cluster-59                         ISNU-cluster-59        67083684   200   SIG   20-21   23.15   8.59   20.78
ISNU-cluster-57                         ISNU-cluster-57        67083682   225   SIG   16-17   25.8    5.05   23.9
ISNU-cluster-486                        ISNU-cluster-486       67083669   210   SIG   19-20   24.36   5.14   21.95
ISNU-cluster-423                        ISNU-cluster-423       67083659   188   SIG   25-26   21.6    9.23   18.74
ISNU-cluster-398                        ISNU-cluster-398       67083653   220   SIG   18-19   25.51   8.67   23.33
ISNU-cluster-395                        ISNU-cluster-395       67083651   200   SIG   20-21   22.97   7.98   20.6
ISNU-cluster-303                        ISNU-cluster-303       67083637   198   SIG   18-19   22.36   6.43   20.1
ISNU-cluster-256                        ISNU-cluster-256       67083627   212   SIG   20-21   24.12   7.97   21.85
ISNU-cluster-247                        ISNU-cluster-247       67083623   210   SIG   19-20   24.35   5.23   21.96
ISNU-cluster-232                        ISNU-cluster-232       67083619   182   SIG   20-21   20.18   4.75   17.87
ISNU-cluster-163                        ISNU-cluster-163       67083611   205   SIG   20-21   23.6    8.27   21.32
ISN-L-88                                                       67083589
                                        ISN-L-is_5_100_92_88_CLU          230   SIG   18-19   25.3     4.8   23.16
ISN-L88                                 ISN-L88                67083587   231   SIG   16-17   25.57    5.5   23.63
ISN-L-44                                                       67083547
                                        ISN-L-is_5_100_92_44_CLU          222   SIG   20-21   25.47   9.27   23.14
ISN-L-33                                                       67083537
                                        ISN-L-is_5_100_92_33_CLU          177   SIG   18-19   19.64   5.49   17.39
ISJ-ISPL-P3-F625                        ISJ-ISPL-P3-F625       67083485   230   SIG   20-21   26.69   8.62   24.43
ISJ-ISPL_P6_D12                         ISJ-ISPL_P6_D12putative67083457   192   SIG   17-18   22.15   7.63   20.27
ISJ-ISPL_P6_D10                         ISJ-ISPL_P6_D10        67083455   192   SIG   15-16   22.49   8.59   20.66
ISJ-ISPL_P3_H8                          ISJ-ISPL_P3_H8         67083439   217   SIG   21-22   25.08   9.07   22.58
ISJ-ISPL_P10_B8_JIN                     ISJ-ISPL_P10_B8_JIN 67083431      220   SIG   22-23   24.39   6.14   21.89
is-all-466                              is-all-466             67083417   191   SIG   24-25   21.55   8.64   18.86
is-all-330                              is-all-330             67083407   198   SIG   18-19   22.14   5.16   19.85
IS-6-12-J-IS612-39                      IS-6-12-J-IS612-39     67083333   201   SIG   20-21   22.43     5    20.22
IS-6-12-J-IS612-27                      IS-6-12-J-IS612-27     67083329   209   SIG   20-21   23.38   5.08   21.13
IS-6-12-J-cluster-453                   IS-6-12-J-cluster-453  67083284   178   SIG   26-27   20.52   8.85   17.64
IS-6-12-J-cluster-38                    IS-6-12-J-cluster-38   67083266   204   SIG   21-22   22.39   4.91   20.12
IS-6-12-J-cluster-365                   IS-6-12-J-cluster-365  67083262   180   SIG   18-19   20.07   8.57   18.04
gi|56159943                             gi|56159942            56159943   236   SIG   18-19   26.3    4.54   24.28
gi|22164320                             gi|22164319            22164320   223   SIG   22-23   24.56   5.54   21.98
gi|22164318                             gi|22164317            22164318   210   SIG   19-20   24.71   5.47   22.34
gi|22164278                             gi|22164277            22164278   220   SIG   21-22   25.42   6.43   23.19
gi|22164276                             gi|22164275            22164276   222   SIG   20-21   25.37   9.19   23.05
gi|22164270                             gi|22164269            22164270   311   SIG   18-19   36.59   5.67   34.45
gi|22164268                             gi|22164267            22164268   306   SIG   17-18   34.27   5.83   32.28
gi|15428310                             gi|15428309            15428310   222   SIG   20-21   25.38   9.12   23.06
gi|15428306                             gi|15428305            15428306   218   SIG   21-22   25.66    8.9   23.22
gi|15428302                             gi|15428301            15428302   222   SIG   20-21   25.52   9.13   23.17
gi|15428298                             gi|15428297            15428298   150   SIG   20-21   17.18    8.7   14.92
gi|15428292                             gi|15428291            15428292   221   SIG   20-21   25.37   8.12   23.1
Group 12: GGY and other immune peptides
gi|56159955                             gi|56159954            56159955   77    SIG   23-24   7.798   9.45   5.26
gi|56159959                             gi|56159958            56159959   161   SIG   16-17   15.37   8.69   13.49
IS-18-24-clu340                         IS-18-24-clu340        67083170   99    SIG   19-20   9.851   8.83   7.668
ISJ-ISPL_P10_H6                         ISJ-ISPL_P10_H6        67083433   72    SIG   22-23   7.214   9.47   4.792
gi|50363174                                                    50363174
                                        Defensin
gi|56159961                             gi|56159960            56159961   74    SIG   22-23 8.106     8.93   5.663
                                        Microplusin family
ISN-L582                                ISN-L582               67083561   124   SIG   19-20 13.42      5.2   11.19
IS-18-24-clu105                         IS-18-24-clu105        67083118   125   SIG   19-20 13.4      5.36   11.18
Group 13: Oxidant metabolism
Glutathione and Thioredoxin peroxidases
ISNU-L-ISN-78                           ISNU-L-ISN-78          67083759   218   SIG   23-24 24.5      8.87   22.27
gi|15428288                             gi|15428287            15428288   221   CYT         24.58     5.77
IS-6-12-J-cluster-514                   IS-6-12-J-cluster-514  67083289   251   SIG   27-28 27.98     5.98   24.86
ISNU-L-ISN-123                          ISNU-L-ISN-123         67083703   232   SIG   18-19 25.64     8.91   23.57
IS-6-12-J-IS612-476                     IS-6-12-J-IS612-476    67083335   233   SIG   16-17 25.71      9.1   23.81
Selenoproteins
ISJ-ISPL-P8-G6                          ISJ-ISPL-P8-G6         67083487   150   SIG   23-24 17.08      6.2   14.33
ISN-L70                                 ISN-L70                67083573   129   SIG   18-19 14.41     4.85   12.3
ISNU-L-ISNU-495A                          ISNU-L-ISNU-495A                    101   CYT           10.99   8.49
Group 14: Isac family
ISNU-L-ISNU-51                            ISNU-L-ISNU-51           67083771   183   SIG   21-22 20.36     4.86    18
ISNU-L-ISN-50                             ISNU-L-ISN-50            67083739   174   SIG   21-22 19.34     4.69   16.99
ISNU-cluster-52                           ISNU-cluster-52nymphal 67083676     173   SIG   21-22 19.26     4.86   16.93
IS-18-24-clu513                           IS-18-24-clu513          67083196   183   SIG   21-22 20.34     4.71   18.01
gi|8896135                                gi|8896134                8896135   184   SIG   21-22 20.31     4.55   17.94
gi|15428346                               gi|15428345              15428346   81    CYT         8.816     3.64
gi|15428300                               gi|15428299              15428300   183   SIG   21-22 20.35     4.61   18.01
Group 15: WC10 family
IS-6-12-J-cluster-62                      IS-6-12-J-cluster-62     67083309   134   SIG   22-23   14.92   5.45   12.31
IS-6-12-J-cluster-96                      IS-6-12-J-cluster-96     67083321   83    SIG   22-23   9.489   5.44   6.824
IS-6-12-J-cluster-97                      IS-6-12-J-cluster-97     67083323   88    SIG   22-23   9.895   7.79   7.239
IS-18-24-clu28                            IS-18-24-clu28           67083166   111   SIG   23-24   12.61   9.17   9.687
ISJ-ISPL_P7_G12                           ISJ-ISPL_P7_G12          67083469   115   SIG   19-20   12.62   5.21   10.32
ISNU-cluster-393                          ISNU-cluster-393         67083649   115   SIG   19-20   12.68   4.77   10.36
IS-18-24-clu27                            IS-18-24-clu27           67083164   114   SIG   23-24   12.89   9.02   9.969
IS-18-24-clu376                           IS-18-24-clu376          67083176   113   SIG   23-24   12.58   6.54   9.992
IS-18-24-clu31                            IS-18-24-clu31           67083168   118   SIG   27-28   13.31   8.86   10.2
IS-18-24-clu123                           IS-18-24-clu123          67083124   117   SIG   24-25   13.3    8.54   10.38
IS-6-12-J-cluster-226                                              67083236
                                          IS-6-12-J-cluster-226putative       115   SIG   19-20   12.77   8.61   10.59
IS-18-24-clu23                            IS-18-24-clu23           67083156   122   SIG   23-24   13.84    8.9   10.92
IS-18-24-clu233                           IS-18-24-clu233          67083158   121   SIG   24-25   13.4    6.27   10.61
IS-18-24-clu50b                           IS-18-24-clu50b          67083194   115   SIG   17-18   12.45   4.91   10.44
ISNU-cluster-489                          ISNU-cluster-489         67083671   115   SIG   19-20   12.56   4.93   10.27
IS-6-12L-5-33                             IS-6-12L-5-33            67083377   113   SIG   18-19   12.62   6.54   10.48
IS-18-24-47                               IS-18-24-clu48           67083112   115   SIG   19-20   12.7    4.52   10.4
ISJ-ISPL_P7_G8                            ISJ-ISPL_P7_G8           67083473   128   SIG   18-19   14.02   8.13   11.91
IS-18-24-clu50                            IS-18-24-clu50           67083192   115   SIG   19-20   12.3    4.61   10.01
ISN-L-85                                  ISN-L-is_5_100_92_85_CLU 67083581   121   SIG   23-24   13.54   5.59   10.97
ISN-L-107                                 ISN-L-is_5_100_92_107_CLU67083495   121   SIG   24-25   13.42    8.1   10.61
gi|22164314                               gi|22164313              22164314   115   SIG   19-20   12.21   5.54   9.921
gi|56159937                               gi|56159936              56159937   119   SIG   29-30   13.33   5.84   10.08
gi|56159949                               gi|56159948              56159949   122   SIG   26-27   13.75   8.42   10.68
ISN-L-68                                  ISN-L-is_5_100_92_68_CLU 67083571   80    SIG   23-24   8.43    7.63   5.67
ISJ-ISPL_P5_G9                            ISJ-ISPL_P5_G9           67083445   136   SIG   21-22   16.14    5.7   13.48
IS-6-12-J-cluster-200                     IS-6-12-J-cluster-200    67083226   60    SIG   19-20   6.58    5.34   4.275
IS-6-12-J-cluster-295                     IS-6-12-J-cluster-295    67083246   125   SIG   22-23   13.78   5.29   11.08
ISJ-ISPL_P9_E5                            ISJ-ISPL_P9_E5           67083483   91    SIG   19-20   10.13    4.8   7.764
IS-6-12-J-cluster-511                     IS-6-12-J-cluster-511    67083287   100   SIG   18-19   10.86   5.29   8.764
IS-6-12L-19                               IS-6-12L-19              67083355   107   SIG   19-20   11.93   8.96   9.687
IS-18-24-clu24                            IS-18-24-clu24           67083160   107   SIG   19-20   11.91   8.18   9.73
gi|22164304                               gi|22164303              22164304   75    SIG   17-18   8.257   5.13   6.288
gi|56159919                               gi|56159918              56159919   104   SIG   18-19   11.55   4.79   9.401
Group 16: LPTS coxy family
IS-6-12L-70                               IS-6-12L-70              67083385   137   SIG   20-21   14.51   4.73   12.05
IS-6-12-J-cluster-588                     IS-6-12-J-cluster-588    67083303   151   SIG   18-19   16.69   5.59   14.35
IS-18-24-clu362                           IS-18-24-clu362          67083174   153   SIG   18-19   16.76   5.02   14.46
IS-6-12-J-cluster-91                      IS-6-12-J-cluster-91     67083319   163   SIG   18-19   17.4    5.06   15.15
IS-6-12-J-cluster-90                      IS-6-12-J-cluster-90     67083317   174   SIG   21-22   18.3      5    15.85
gi|56159933                               gi|56159932              56159933   174   SIG   18-19   18.65   5.48   16.4
ISNU-cluster-358                          ISNU-cluster-358         67083645   165   SIG   18-19   17.82   4.74   15.57
ISN-L-167                                 ISN-L-is_5_100_92_167_CLU67083511   165   SIG   23-24   17.79   4.54   15.13
gi|56159925                               gi|56159924              56159925   131   SIG   23-24   15.03   5.38   11.97
gi|12002008                               gi|12002007              12002008   152   SIG   18-19   16.34   5.18   14.06
ISNU-L-ISN-77                             ISNU-L-ISN-77            67083757   167   SIG   18-19   17.55   5.07   15.27
Group 17: Other anti-protease polypeptides
Serpins
gi|22164288                               gi|22164287              22164288   213   SIG   16-17 23.84     5.95   21.74
gi|56159953                               gi|56159952              56159953   393   SIG   16-17 43.59     5.04   41.68
Cystatins
ISN-L-110                                 ISN-L-is_5_100_92_110_CLU67083499   132   SIG   17-18 14.38     5.33   12.54
gi|22164282                            gi|22164281            22164282     133   SIG   19-20   14.3    5.46    12.26
Probable TIL domain peptides
ISN-L181A                              ISN-L181A              67083517     105   SIG   19-20 11.65     4.39    9.332
ISN-L181B                              ISN-L181B              67083519     105   SIG   19-20 11.7      4.31    9.386
Group 18: Mucins
ISJ-ISPL_P7_G3                         ISJ-ISPL_P7_G3           67083471   127   SIG   24-25   13.98   3.92    11.26
IS-6-12-J-cluster-211                  IS-6-12-J-cluster-211    67083232   176   SIG   19-20   18.29   9.86    15.96
IS-6-12-J-cluster-385                  IS-6-12-J-cluster-385    67083268   93    SIG   22-23   9.422   8.63    7.101
IS-6-12-J-IS612-484                    IS-6-12-J-IS612-484      67083337   143   SIG   20-21   15.58    6.7    13.25
IS-18-24-clu102salivary                IS-18-24-clu102salivary 67083116    125   SIG   20-21    14     5.41    11.81
ISJ-ISPL_P3_H12                        ISJ-ISPL_P3_H12          67083437   105   SIG   17-18   10.61    4.1    8.62
IS-6-12-J-cluster-530                                           67083293
                                       IS-6-12-J-cluster-530putative       105   SIG   17-18   10.63   4.06    8.621
Group 19: IS6 family
gi|56159957                            gi|56159956            56159957     116   SIG   25-26 12.35     4.36    9.703
IS-18-24-clu144                        IS-18-24-clu144        67083130     125   SIG   23-24 13.4      4.38    10.91
is-all-704                             is-all-704             67083425     130   SIG   20-21 14.18     8.79    11.82
gi|29649848                                                   29649848
Group 20: 12 kDa family
IS-18-24-clu96                         IS-18-24-clu96         67083210     133   SIG   22-23 14.32     3.97    11.66
ISJ-ISPL_P7_F12                        ISJ-ISPL_P7_F12putative67083467     133   SIG   22-23 14.6      4.29    12.01
gi|56159931                            gi|56159930            56159931     135   BL    16-17 14.98     4.27    12.98
Group 21: 26 kDa family
gi|15428304                            gi|15428303            15428304     233   SIG   18-19 26.41     4.69    24.19
gi|56159927                            gi|56159926            56159927     190   SIG   21-22 21.66     4.76    19.02
Group 22: 30 kDa protein
ISJ-ISPL_P8_D4                         ISJ-ISPL_P8_D4putative 67083477     284   SIG   23-24 32.28     6.67    29.5
IS-6-12-J-cluster-330                  IS-6-12-J-cluster-330  67083260     294   SIG   33-34 33.49     6.72    29.64
Group 23: Toxin-like
IS-6-12-J-cluster-41                   IS-6-12-J-cluster-41   67083276     72    SIG   23-24 8.231      9.3    5.583
IS-6-12-J-cluster-42                   IS-6-12-J-cluster-42   67083278     88    SIG   23-24 9.238     4.39    6.555
Group 24: SRAEL family
IS-6-12-J-cluster-399                  IS-6-12-J-cluster-399    67083274   159   SIG   17-18 18.34     5.92    16.4
ISNU-cluster-482                       ISNU-cluster-482putative 67083665   210   SIG   17-18 24.35     7.48    22.42
Group 25: Other enzymes
gi|22164290                            gi|22164289            22164290     350   SIG   29-30 38.21     8.11    34.73
gi|55736035                            gi|55736034            55736035     394   SIG   18-19 42.37     8.45    40.22
ISNU-cluster-162                       ISNU-cluster-162       67083609     273   SIG   19-20 29.88     9.36    27.84
ISNU-cluster-390                       ISNU-cluster-390       67083889     98    CYT         11.34     5.16
ISNU-cluster-117                       ISNU-cluster-117       67083603     162   SIG   27-28 18.37     5.02    15.17
ISN-L905                               ISJ-ISPL_P8_G7         67083591     95    SIG   38-39 10.83     8.25    6.452
ISJ-ISPL_P2_B3                         ISJ-ISPL_P2_B3         67083435     124   IND         13.46     8.11
Group 26:Other peptides and proteins
IS-6-12-J-IS612-504                    IS-6-12-J-IS612-504      67083339   228   SIG   20-21   24.89   8.36    22.57
IS-6-12-J-cluster-442                                           67083282
                                       IS-6-12-J-cluster-442putative       49    SIG   32-33   5.519   6.88    1.446
IS-6-12-J-cluster-165                                           67083224
                                       IS-6-12-J-cluster-165putative       38    SIG   23-24   4.512   8.94    1.651
IS-6-12-J-cluster-263                                           67083240
                                       IS-6-12-J-cluster-263putative       37    SIG   18-19   3.83    9.49    1.749
ISNU-cluster-283                       ISNU-cluster-283         67083631   37    SIG   20-21   4.389   10.24   1.845
IS-6-12-J-cluster-390                                           67083270
                                       IS-6-12-J-cluster-390putative       50    SIG   25-26    5.5     9.8    2.429
IS-6-12-J-cluster-297                  IS-6-12-J-cluster-297    67083248   52    SIG   26-27   5.374   11.11   2.632
IS-6-12L-34                            IS-6-12L-34              67083357   65    SIG   36-37   7.006   10.04   2.733
ISNU-cluster-333                       ISNU-cluster-333         67083641   49    SIG   21-22   5.453   9.82    2.809
IS-6-12-J-cluster-105                  IS-6-12-J-cluster-105    67083214   44    SIG   19-20   5.219   11.54   2.941
IS-6-12-J-cluster-126                                           67083218
                                       IS-6-12-J-cluster-126putative       52    SIG   16-17   5.905     6     3.86
gi|22164300                            gi|22164299              22164300   61    SIG   27-28   7.162   10.43   3.99
IS-6-12-J-cluster-207                  IS-6-12-J-cluster-207    67083230   54    SIG   20-21   6.328   7.92    4.047
IS-6-12-J-cluster-328                                           67083258
                                       IS-6-12-J-cluster-328putative       65    SIG   24-25   7.081   6.69    4.183
ISNU-L-IS-283A                         ISNU-L-IS-283A           67083692   66    SIG   22-23   7.47    9.25    4.635
ISNU-cluster-525                       ISNU-cluster-525         67083680   67    SIG   22-23   7.425   9.21    4.736
IS-6-12-J-cluster-423                                           67083280
                                       IS-6-12-J-cluster-423putative       69    BL    25-26   7.784    9.1    4.752
ISUFJ-cluster-310                      ISUFJ-cluster-310        67083775   84    SIG   37-38   9.415   11.48   5.06
ISJ-ISPL_P6_G3                         ISJ-ISPL_P6_G3           67083465   75    SIG   20-21   8.201   11.3    5.823
IS-6-12-J-cluster-534   IS-6-12-J-cluster-534    67083295   85    SIG   25-26 9.707   7.76    6.719
is-all-335              is-all-335               67083411   105    BL   28-29 11.77   3.95    8.438
IS-6-12-J-cluster-602                            67083307
                        IS-6-12-J-cluster-602putative       99    SIG   19-20 11.21   10.75   8.783
ISJ-ISPL_P6_E9          ISJ-ISPL_P6_E9           67083459   108   SIG   23-24 11.92   8.53    9.17
IS-6-12-J-cluster-139   IS-6-12-J-cluster-139    67083220   118   SIG   33-34 13.48   9.81    9.42
ISUFL108                ISUFL108                 67083785   110   SIG   20-21 12.11   10.8    9.703
gi|56159963             gi|56159962              56159963   114   SIG   19-20 12.52   4.17    10.41
IS-18-24-34             IS-18-24-34              67083110   117   SIG   19-20 12.76    7.5    10.52
gi|56159945             gi|56159944              56159945   138   SIG   29-30 15.32   6.81    12.23
IS-18-24-clu147         IS-18-24-clu147          67083132   131   SIG   17-18 14.3    4.52    12.34
is-all-465              is-all-465               67083415   145   SIG   25-26 15.68   8.33    12.88
IS-6-12-J-cluster-370                            67083264
                        IS-6-12-J-cluster-370putative       153   SIG   27-28 17.72   10.24   14.51
ISN-L179                ISN-L179                 67083515   150   SIG   19-20 17.19   7.51    14.9
IS-6-12-J-cluster-204   IS-6-12-J-cluster-204    67083228   151   SIG   16-17 16.13   8.08    14.38
gi|56159951             gi|56159950              56159951   171   SIG   21-22 18.6    6.72    16.05
ISUFJ-cluster-89        ISUFJ-cluster-89Putative 67083783   194   SIG   23-24 20.35   4.99    17.71
IS-6-12-J-cluster-218   IS-6-12-J-cluster-218    67083234   192   SIG   31-32 21.26   4.65    17.9
ISUFJ-cluster-333       ISUFJ-cluster-333        67083777   196   SIG   29-30 21.69   8.68    18.15
IS-6-12-J-cluster-69    IS-6-12-J-cluster-69     67083311   179   SIG   21-22 21.09   9.68    18.43
IS-6-12-J-IS612-525                              67083341
                        IS-6-12-J-IS612-525putative         212   SIG   27-28 23.23   5.67    20.15
IS-6-12-J-cluster-523   IS-6-12-J-cluster-523    67083291   218   SIG   17-18 24.51   5.96    22.55
ISNU-cluster-102        ISNU-cluster-102         67083599   282   SIG   20-21 32.5    9.47    30.2
IS-6-12-J-cluster-593   IS-6-12-J-cluster-593    67083305   234   CYT         27.32   8.72
gi|56159929             gi|56159928              56159929   135    BL         14.34   9.88
gi|51243761             gi|51243760              51243761         SIG   16-17 47.62   4.54    45.7
IS-6-12-J-cluster-114   IS-6-12-J-cluster-114    67084105   244   SIG   21-22 27.58   4.96    25.28
ISN-L-177               ISN-L-is_5_100_92_177_CLU67083915   122   SIG   17-18 13.25   11.29   11.41
                                                                                        ------------------------------------------------------------------SDS-PAG

                                                                                              ISGNV-9
                                                                                               [NHAI]-
                                                                                             [DEPVKL
                                                                                                   ]-
                                                                                             [EARYPK       ISGNV-11
                                                                                              ]-[DQE]-      [EHAM]-
                                                                                                 [AV]-     [NTKL]-E-
                                                                                               [GEK]-         [QRL]-
                                   Number           GAMMA-                                      [TRK]-       [GYM]-
                                      of             COXY                                    [DNQTA]-       [DGV]-T-                            ISGNV-16
                                   possible         GLUTAMI Predicted                            [NP]-      R-P-A-S-                            [QEHA]-N-
        No.      % Perc Perc       HO-Pro Number NATION Tyr-SO4 -                    RGD     [EAY]-E-I-      [QE]-K-                             X-Q-X-G-
       glyc    Ser + ent ent Pro+ [LPAE]-P- of Pro- E-X(3)-E- Prosite              flanked    Q-K-Q-S-     [DN]-R-E-                            T-R-P-A-A-
pI     sites    Thr Gly Pro Gly       G      Gly's    X-C.     rules                by Cys     L-X-I-Y.     G-X-D-Y.                             E-E-N-R.


9.07    3      16.5   9.9    5.0    14.9            GAMMA-COXY -> EenrEgC 32                                                                    ISGNV-11B -> HNcknGTRPtsEENR 21



8.91    5      14.0   10.7   7.4    18.2            GAMMA-COXY -> EenrEgC 32                              ISGNV-11 -> HNcQnGTRPASEeNREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEENR 21




8.74    4      13.2   9.1    7.4    16.5            GAMMA-COXY -> EenrEgC 32                              ISGNV-11 -> HNcQnGTRPASEeNREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEENR 21



8.89    5      16.0   10.4   6.4    16.8            GAMMA-COXY -> EenrEgC 32                              ISGNV-11 -> HNcQnGTRPASEeNREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEENR 21




9.27    3      14.2   10.0   5.8    15.8            GAMMA-COXY -> EknrEgC 32                              ISGNV-11 -> HNcQnGTRPASEKNREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEkNR 21



9.25    5      16.0   10.4   6.4    16.8            GAMMA-COXY -> EknrEgC 32                              ISGNV-11 -> HNcQnGTRPtSEKNREGcDf 21   ISGNV-11B -> HNcQnGTRPtsEkNR 21



9.03    5      15.2   10.4   6.4    16.8            GAMMA-COXY -> EenrEgC 32                              ISGNV-11 -> HNcQnGTRPASEeNREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEENR 21



9.23    5      16.5   9.9    6.6    16.5            GAMMA-COXY -> EekrEgC 32                                                                    ISGNV-11B -> HNcknGTRPAsEEkR 21



9.15    1      16.7   10.0   4.2    14.2            GAMMA-COXY -> EqnrEgC 32   1                          ISGNV-11 -> HNcQnGTRPASEqNREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEqNR 21




 8.9    4      13.2   9.9    7.4    17.4            GAMMA-COXY -> EenrEgC 32                              ISGNV-11 -> HNcknGTRPASEeNREGcDY 21   ISGNV-11B -> HNcknGTRPAsEENR 21



9.14    1      15.8   10.0   4.2    14.2            GAMMA-COXY -> EekrEgC 32   1                          ISGNV-11 -> HNcQnGTRPASEekREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEEkR 21



 8.9    3      13.2   9.9    5.8    15.7            GAMMA-COXY -> EenrEgC 32                              ISGNV-11 -> HNcknGTRPASEeNREGcDY 21   ISGNV-11B -> HNcknGTRPAsEENR 21



 8.9    4      13.2   9.1    7.4    16.5            GAMMA-COXY -> EenrEgC 32                              ISGNV-11 -> HNcknGTRPASEeNREGcDY 21   ISGNV-11B -> HNcknGTRPAsEENR 21



 8.9    3      13.2   10.7   6.6    17.4            GAMMA-COXY -> EenrEgC 32                              ISGNV-11 -> HNcknGTRPASEeNREGcDY 21   ISGNV-11B -> HNcknGTRPAsEENR 21



8.89    6      15.2   10.4   7.2    17.6            GAMMA-COXY -> EenrEgC 32                              ISGNV-11 -> HNcQnGTRPASEeNREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEENR 21



9.04    5      15.7   9.9    6.6    16.5            GAMMA-COXY -> EenrEgC 32                              ISGNV-11 -> HNcknGTRPASEeNREGcDY 21   ISGNV-11B -> HNcknGTRPAsEENR 21



9.18    6      15.7   9.9    6.6    16.5            GAMMA-COXY -> EknrEgC 32                              ISGNV-11 -> HNcQnGTRPASEKNREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEkNR 21



8.75    5      14.9   10.7   5.0    15.7            GAMMA-COXY -> EenrEgC 32                              ISGNV-11 -> HNcQnGTRPASEeNREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEENR 21



 8.9    4      14.9   10.7   5.0    15.7            GAMMA-COXY -> EenrEgC 32                              ISGNV-11 -> HNcknGTRPASEeNREGcDY 21   ISGNV-11B -> HNcknGTRPAsEENR 21



8.88    3      14.4   9.6    4.8    14.4            GAMMA-COXY -> EqdrEgC 32   1                          ISGNV-11 -> HNcQnGTRPASEqDREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEqdR 21



9.14    5      16.7   9.5    4.0    13.5            GAMMA-COXY -> EqnrEgC 33   1                          ISGNV-11 -> HNcQnGTRPASEqNREGcDY 22   ISGNV-11B -> HNcQnGTRPAsEqNR 22



9.32    2      18.0   8.2    7.4    15.6                                       1                          ISGNV-11 -> ETcRnGTRPASQtDREGcDY 21




9.23    2      18.0   8.2    7.4    15.6                                       1                          ISGNV-11 -> ETcRnGTRPASQtDREGcDY 21




9.32    2      18.0   8.2    7.4    15.6                                       1                          ISGNV-11 -> ETcRnGTRPAtQtDREGcDY 21




9.13    4      19.0   7.4    6.6    14.0                                       1                          ISGNV-11 -> ETcRnGTRPASQteREGcDY 21




9.35    2      17.2   8.2    7.4    15.6                                                                  ISGNV-11 -> ETcRnGTRPASQtqREGcDY 21




9.22    2      18.2   8.3    7.4    15.7                                       1                          ISGNV-11 -> ETcRnGTRPASQtDREGcDY 21




9.13    4      18.9   7.4    7.4    14.8                                       2                          ISGNV-11 -> ETcRnGTRPASQtDREGcDY 21




9.22    3      19.0   8.3    6.6    14.9                                       1                          ISGNV-11 -> ETcRnGTRPASQteREGcDY 21




9.37    2      18.9   8.2    7.4    15.6                                                                  ISGNV-11 -> ETcRnGTRPASQtqREGcDY 21




9.32    2      18.0   8.2    7.4    15.6                                       1                          ISGNV-11 -> ETcRnGTRPASQtDREGcDY 21




9.32    2      18.0   8.2    7.4    15.6                                       1                          ISGNV-11 -> ETcRnGTRPASQtDREGcDY 21




9.22    2      18.2   8.3    7.4    15.7                                       1                          ISGNV-11 -> ETcRnGTRPASQtDREGcDY 21




9.13    1      15.7   9.1    7.4    16.5                                       1                          ISGNV-11 -> ETcRnGTRPASQteREGcDY 21




9.35    2      18.9   9.0    7.4    16.4       1
9.23    4      18.9   8.2    7.4    15.6                                       2                          ISGNV-11 -> ETcRnGTRPASQtDREGcDY 21




8.63    6      13.4   4.7    10.2   15.0
9.01    4      11.6   7.7    6.5    14.2            GAMMA-COXY -> EenrEgC 66


8.84    4      11.5   5.4    9.2    14.6
9.52    4      12.7   5.4    8.4    13.9                                       1
4.63    2      10.2   7.6    7.6    15.3
7.73    6      15.8   10.0   6.7    16.7            GAMMA-COXY -> EenrEgC 32                              ISGNV-11 -> HNcQnGTRPASEeNREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEENR 21




4.2     1      12.7   8.8    2.0    10.8                                                                                                        ISGNV-11B -> HdcQnGTRPAsEEkR 21



4.2     1      12.5   8.3    2.1    10.4            GAMMA-COXY -> EekrEgC 26                                                                    ISGNV-11B -> HdcQnGTRPAsEEkR 15
4.35   0   13.2   9.9    2.2    12.1           GAMMA-COXY -> EekrEgC 32                                             ISGNV-11B -> HdcQnGTRPAsEEkR 21



4.22   0   12.1   9.9    2.2    12.1           GAMMA-COXY -> EekrEgC 32   1                                         ISGNV-11B -> HdcQnGTRPAsEEkR 21



4.21   0   12.1   8.8    2.2    11.0           GAMMA-COXY -> EekrEgC 32   1                                         ISGNV-11B -> HdcQnGTRPAsEEkR 21



4.22   0   16.5   8.8    2.2    11.0           GAMMA-COXY -> EekrEgC 32   1   ISGNV-11 -> HNcQnGTRPASEekREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEEkR 21




4.35   1   14.3   9.9    2.2    12.1           GAMMA-COXY -> EekrEgC 32   1   ISGNV-11 -> HNcQnGTRPASEekREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEEkR 21




4.22   1   14.3   9.9    2.2    12.1           GAMMA-COXY -> EenrEgC 32   1   ISGNV-11 -> HdcQnGTRPASEeNREGcDY 21   ISGNV-11B -> HdcQnGTRPAsEENR 21



4.22   0   15.4   9.9    2.2    12.1           GAMMA-COXY -> EekrEgC 32   1   ISGNV-11 -> HNcQnGTRPASEekREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEEkR 21




4.22   0   14.3   9.9    2.2    12.1           GAMMA-COXY -> EekrEgC 32   1   ISGNV-11 -> HNcQnGTRPASEekREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEEkR 21



4.08   0   13.2   11.0   2.2    13.2           GAMMA-COXY -> EenrEgC 32   1   ISGNV-11 -> HNcQnGTRPASEeNREGcDY 21   ISGNV-11B -> HNcQnGTRPAsEENR 21




8.75   0   8.1    1.6    4.8    6.5
4.45   4   14.9   10.9   5.9    16.8           GAMMA-COXY -> EenrEgC 32       ISGNV-11 -> HNcknGTRPASEeNREGcDY 21   ISGNV-11B -> HNcknGTRPAsEENR 21




5.21   1   6.3    4.2    10.4   14.6   1   2
7.75   1   10.4   8.3    9.4    17.7   1   2
7.75   1   11.5   8.3    9.4    17.7   1   2
7.73   0   6.3    7.3    10.4   17.7   1   2
 6.7   0   8.8    6.6    6.6    13.2   1   2
6.31   0   6.6    7.7    8.8    16.5   1   2
6.28   0   7.7    7.7    8.8    16.5   1   2
7.73   0   12.5   8.3    5.2    13.5       2                              1
8.26   0   7.3    7.3    7.3    14.6   1   2                              1
8.26   0   7.3    7.3    7.3    14.6   1   2                              1
 6.7   0   8.8    6.6    7.7    14.3   1   2
 8.8   0   5.2    8.3    9.4    17.7   1   2
9.22   0   8.5    7.3    3.7    11.0
9.61   1   12.2   9.8    3.7    13.4       1
4.92   0   13.0   8.7    4.3    13.0   1   1
5.37   0   17.2   8.0    3.4    11.5   1   1
6.62   1   16.3   6.5    4.3    10.9   1   1
 8.8   0   9.9    7.4    6.2    13.6   1   1
4.95   0   10.3   6.4    6.4    12.8           GAMMA-COXY -> EkcqEeC 69


6.73   0   12.8   6.4    6.4    12.8           GAMMA-COXY -> EkcqEeC 69


8.22   0   12.8   6.4    6.4    12.8   1   1
8.62   0   9.6    12.8   7.4    20.2   1   1
8.94   1   10.5   7.4    6.3    13.7
8.94   0   10.5   7.4    6.3    13.7
5.62   2   21.2   5.9    5.9    11.8           GAMMA-COXY -> EkckEnC 69


5.62   1   15.9   7.3    7.3    14.6
4.46   3   18.8   8.2    5.9    14.1
4.35   2   17.6   7.1    5.9    12.9
4.46   0   14.1   7.1    7.1    14.1
4.84   0   12.8   8.1    7.0    15.1
4.91   0   11.8   8.2    4.7    12.9
4.75   0   14.3   6.0    6.0    11.9   1   1
5.64   0   12.9   9.4    7.1    16.5   1   1
  5    0   11.8   9.4    7.1    16.5
6.72   2   16.0   7.6    9.5    17.1   1   2
4.57   0   10.7   6.0    4.8    10.7
4.63   0   14.3   8.3    6.0    14.3
8.83   0   11.9   8.3    8.3    16.7   1   2
 9.4   0   11.0   7.7    8.8    16.5
9.15   0   9.9    7.7    9.9    17.6
9.44   0   11.0   7.7    8.8    16.5
6.06   0   7.2    10.3   7.2    17.5   1   1
8.84   0   11.1   9.1    7.1    16.2   1   1
5.65   0   9.3    9.3    8.2    17.5   1   1
7.47   1   14.9   6.4    4.3    10.6
7.47   1   14.9   6.4    4.3    10.6
 7.6   1   13.3   4.0    2.7    6.7
6.81   0   12.8   8.5    5.3    13.8
6.81   0   11.7   8.5    5.3    13.8
6.81   0   12.8   8.5    4.3    12.8
8.75    0    14.3   7.7    4.4    12.1       1
8.19    0    14.8   6.2    3.7    9.9
4.84    0    13.6   6.2    6.2    12.3
4.91    0    13.4   6.1    6.1    12.2
8.42    0    7.3    6.3    9.4    15.6   1   2
6.77    0    14.9   8.5    4.3    12.8
8.95    0    5.2    13.5   9.4    22.9   1   4
7.74    1    16.9   8.5    4.2    12.7       3
8.89    5    12.6   3.2    8.4    11.6       1
8.29    0    8.2    11.3   9.3    20.6   1   1

9.21    0    6.6    8.0    2.9    10.9
6.88    0    12.3   7.1    3.9    11.0   1   1
4.76    0    12.5   8.9    5.4    14.3   1   1                               2
4.52    0    15.2   9.1    3.0    12.1           GAMMA-COXY -> EeckEtC 144



5.31    0    14.9   12.1   4.0    16.1   1   1
9.25    15   18.8   5.7    8.5    14.2       1
8.72    18   20.0   4.6    5.7    10.3
8.92    15   20.2   3.9    7.9    11.8
9.02    23   24.1   5.3    7.5    12.8
9.13    23   23.7   4.2    7.9    12.1
 7.9    0    14.1   3.9    1.0    4.9        1

5.32    4    12.8   6.6    5.0    11.6                                       1
5.34    2    12.3   5.5    5.8    11.3       1                               1
7.24    0    11.3   7.5    5.0    12.5       1                               1
8.79    1    17.0   7.1    4.3    11.4   1   2
8.86    0    13.0   5.8    5.2    10.9                                       1
8.59    1    14.2   6.1    5.5    11.5       2                               1
8.23    0    11.3   7.8    5.3    13.2       1                               1
8.23    1    12.1   6.5    5.6    12.1       1

6.97    0    4.2    21.9   6.3    28.1   1   2
9.39    5    17.9   14.9   16.4   31.3   2   5
6.73    6    17.2   15.6   17.2   32.8   2   6
6.74    10   21.5   15.4   15.4   30.8   2   5
8.08    9    22.7   15.2   18.2   33.3   3   5
8.07    5    13.8   12.3   20.0   32.3   3   4
8.07    3    12.5   14.1   18.8   32.8   2   4
6.05    8    20.0   16.9   16.9   33.8   2   6
9.39    6    17.9   14.9   16.4   31.3   2   5
8.06    8    20.0   15.4   16.9   32.3   2   6
4.67    4    12.3   19.8   8.6    28.4   1   2
8.08    6    18.8   15.6   20.3   35.9   3   5
8.96    8    23.1   12.3   18.5   30.8   3   3
8.06    7    21.5   16.9   13.8   30.8   2   4
4.79    3    8.3    20.8   11.1   31.9   1   1
4.75    2    9.5    18.9   12.2   31.1   2   3
6.12    8    23.4   12.5   17.2   29.7   3   4
8.92    9    14.0   11.6   26.7   38.4   3   5
6.74    9    20.3   14.1   15.6   29.7   2   4
  6     6    17.2   17.2   17.2   34.4   2   6
8.06    9    20.0   15.4   16.9   32.3   2   6
5.08    6    13.1   22.6   10.7   33.3   2   4                               2
10.26   4    13.6   7.3    13.6   20.9   1   1
8.53    10   16.3   12.8   22.1   34.9   3   4
 9.1    12   19.0   11.0   19.0   30.0   5   5
4.51    1    9.7    19.4   9.7    29.0   2   2
8.07    10   21.5   10.8   16.9   27.7   3   3
4.35    4    14.3   24.3   7.1    31.4   2   2                               1
4.48    4    13.6   19.8   9.9    29.6   2   3
6.74    9    20.0   15.4   15.4   30.8   2   5
9.21   1    8.0    17.3   12.0   29.3   1   2
6.74   10   20.0   15.4   15.4   30.8   2   5
 8.9   7    18.5   13.8   18.5   32.3   3   4
 12    0    3.3    42.2   0.0    42.2
9.76   6    20.9   11.6   16.3   27.9   1   3
8.07   9    20.0   15.4   13.8   29.2   2   3
5.38   8    20.3   15.6   17.2   32.8   2   6
10.1   7    19.4   13.4   14.9   28.4   2   4
 9.5   7    19.4   14.9   14.9   29.9   2   5
8.07   6    16.9   12.3   20.0   32.3   3   4
8.08   9    20.0   13.8   15.4   29.2   2   5
8.96   5    15.4   12.3   20.0   32.3   3   4
6.74   5    16.9   12.3   20.0   32.3   3   4
 9.5   5    15.4   12.3   20.0   32.3   3   4
8.06   5    15.4   16.9   20.0   36.9   3   6
6.73   8    20.0   15.4   16.9   32.3   2   6
8.06   7    18.5   16.9   18.5   35.4   2   6
8.08   6    16.9   18.5   18.5   36.9   2   5
5.32   7    20.4   11.1   14.8   25.9   1   2

4.79   0    9.0    9.6    6.2    15.7           3
4.78   0    11.8   9.6    5.6    15.2       1   1
5.59   0    11.9   8.5    5.1    13.6       1
 5.2   0    11.8   9.6    7.9    17.4   1   2
4.79   0    7.3    10.7   7.3    18.0   1   2   1
5.27   0    10.8   7.5    5.4    12.9       1   1

9.59   0    10.6   4.5    10.6   15.2       1
 9.1   0    4.6    7.7    10.8   18.5   1   1
8.86   0    10.4   6.0    1.5    7.5
8.99   0    11.8   4.4    4.4    8.8
9.55   0    9.2    1.5    10.8   12.3
8.94   0    10.6   7.6    7.6    15.2
7.77   1    11.9   6.0    10.4   16.4
8.89   0    13.8   3.1    3.1    6.2
 9.1   0    13.8   4.6    3.1    7.7
8.65   0    11.4   8.6    5.7    14.3
8.94   0    8.7    7.2    8.7    15.9       1
8.64   0    13.0   5.8    4.3    10.1
8.89   0    15.9   5.8    4.3    10.1
8.94   0    10.1   7.2    2.9    10.1
8.33   0    16.7   4.5    7.6    12.1
8.62   2    13.4   6.0    7.5    13.4
9.27   0    12.1   7.6    7.6    15.2

 4.6   0    8.9    8.9    1.3    10.1
5.28   0    9.2    9.2    9.2    18.3       1
5.66   0    7.6    6.3    1.3    7.6            1   ISGNV-9 -> NVKEAGKTdYEIQeQSLlIf 18




8.48   0    14.9   7.9    4.0    11.9
8.17   0    12.9   7.9    6.9    14.9
5.71   0    7.6    6.3    1.3    7.6                ISGNV-9 -> NVKEAGKTNYEIQeQSLlIf 18




7.71   0    7.9    8.9    5.0    13.9       1
6.36   0    10.1   7.6    1.3    8.9                ISGNV-9 -> NVEEAGKssYqIQKQSLiIf 18




 8.7   0    9.9    9.9    3.6    13.5       1
7.94   0    8.6    10.5   3.8    14.3       1
5.28   0    9.2    9.2    9.2    18.3       1
 7.7   0    11.9   8.9    5.9    14.9
6.34   0    7.6    7.6    1.3    8.9                ISGNV-9 -> NVKEAGKsNYEIQegSLlIf 18




       0    11.4   6.7    4.7    11.4   1   1
       1    12.7   6.8    3.9    10.7   1   1   4
6.81   1    12.7   6.8    3.9    10.7   1   1   4
       3    13.1   6.5    3.8   10.4   1   1                              1

  5    0    10.0   6.7    8.3   15.0   1   1                                  1
4.39   0    8.3    8.3    8.3   16.7   1   1                                  1
4.86   0    9.8    6.6    4.9   11.5       1                                  1
3.74   3    18.2   7.3    9.1   16.4   1   2                              1   1


 4     5    20.7   8.1    8.1   16.2       2                              1



8.79   0    14.9   13.9   2.0   15.8       1                              1
7.65   0    14.2   4.7    4.7   9.5
8.44   0    13.4   9.2    5.0   14.3
6.34   0    11.6   6.6    5.8   12.4
8.91   0    9.2    7.1    5.0   12.1
8.85   0    13.3   7.1    3.1   10.2
6.73   0    7.1    9.3    4.3   13.6   1   1
6.98   0    9.8    3.7    2.4   6.1
8.99   1    11.1   5.6    6.3   11.9       1
5.76   0    13.2   7.9    3.5   11.4   1   1
5.59   1    17.2   7.8    1.7   9.5
7.08   0    15.8   5.3    2.6   7.9
8.18   0    11.4   6.1    3.5   9.6
9.33   0    9.6    4.0    6.4   10.4
 5.1   0    10.5   8.8    5.3   14.0   1   1
9.04   0    9.9    6.3    3.6   9.9
7.03   0    13.2   6.1    3.5   9.6
7.02   0    7.8    6.9    8.6   15.5       1
8.63   0    13.1   5.6    4.7   10.3
8.24   0    15.0   6.4    3.6   10.0       1
6.99   1    11.7   4.4    6.6   10.9       1
8.52   0    14.6   6.6    2.2   8.8            GAMMA-COXY -> EhvkEaC 49


8.12   0    7.6    9.1    5.3   14.4   1   1
8.35   0    16.7   8.3    3.3   11.7
8.04   0    16.7   7.5    3.3   10.8
8.75   2    11.0   5.9    6.8   12.7       1
5.27   0    17.9   8.9    3.6   12.5       1
8.62   0    9.5    9.5    4.8   14.3
8.39   0    17.9   7.5    4.7   12.3
6.33   0    9.4    6.8    6.0   12.8       1
8.45   0    17.0   8.0    5.4   13.4       1
8.34   1    17.9   6.8    5.1   12.0
7.57   0    9.4    11.0   7.9   18.9       1
6.68   0    9.1    9.1    5.0   14.0           GAMMA-COXY -> EslqEgC 31


 7.7   0    11.4   6.1    4.4   10.5
7.03   2    12.5   6.9    6.3   13.2
8.86   1    14.1   5.2    4.4   9.6        1
 7.7   0    15.8   7.9    2.6   10.5

6.38   0    10.8   3.4    2.8   6.3        1                              1
8.87   3    16.2   2.1    3.7   5.8
8.96   1    15.0   2.7    6.8   9.5
5.15   0    15.7   5.5    9.7   15.2   1   2
5.04   1    15.9   6.6    4.9   11.5                                      1
 9.1   2    13.4   6.0    6.9   13.0
5.74   0    10.6   7.4    6.3   13.8       2                              2
7.55   2    14.8   4.6    6.5   11.1
8.49   11   17.4   5.7    5.2   10.9       1
9.12   13   18.7   4.8    5.7   10.4       1
8.87   10   17.1   5.9    6.3   12.2       2
       0    13.8   7.9    2.0   9.9        1                              1
6.07   3    18.9   4.5    7.7    12.2                                       1
6.87   2    16.5   4.1    6.6    10.7   1   2                               1
8.54   0    18.0   2.5    4.0    6.5                                        1
 5.3   8    16.9   5.3    5.3    10.7                                       1
5.21   0    11.4   6.2    2.9    9.0        1                               1
 9.2   0    13.3   4.3    4.8    9.0    1   1
8.37   5    17.3   3.2    6.8    10.0                                       1
7.66   0    16.0   4.5    5.5    10.0                                       1
6.84   0    13.6   5.1    6.6    11.6
7.68   0    12.7   4.7    6.1    10.8       1                               1
5.33   0    13.8   4.8    2.9    7.6        1
4.77   0    11.5   10.4   4.4    14.8       1
8.14   6    16.1   4.4    4.4    8.8
4.71   3    18.7   7.4    7.8    15.2       1                               1
 5.5   3    18.6   6.5    6.9    13.4       1
 9.1   8    16.7   6.3    8.1    14.4       1
5.71   0    10.2   9.6    8.5    18.1   1   2                               1
8.47   14   20.0   5.7    5.2    10.9       1
7.77   0    13.0   5.2    3.6    8.9                                        1
 8.9   0    12.0   3.6    5.2    8.9
 9.1   4    15.2   5.5    6.5    12.0
6.06   0    18.2   5.9    6.8    12.7                                       1
8.69   0    15.2   4.2    3.1    7.3
5.29   6    17.2   6.6    6.1    12.6   1   1                               1
 5.2   1    19.4   5.5    2.5    8.0                                        2
5.19   0    16.3   5.3    3.8    9.1                                        1
9.06   0    13.5   8.4    3.9    12.4
  5    13   21.6   4.4    4.9    9.3        1
9.05   0    20.6   5.0    2.2    7.2
4.63   5    22.5   4.7    3.0    7.6        1
5.42   1    18.8   5.8    8.5    14.3           GAMMA-COXY -> EvwkEdC 212   1
5.49   0    10.5   5.2    3.3    8.6        1                               2
6.76   0    13.2   5.5    3.6    9.1
8.99   6    14.9   7.2    8.1    15.3       1
5.54   0    15.1   3.2    2.9    6.1                                        1
5.84   0    15.4   4.2    5.9    10.1
8.88   7    16.7   6.3    8.1    14.4       1
8.73   3    14.7   3.2    7.3    10.6                                       1
8.86   6    15.8   6.3    7.7    14.0       1
7.58   4    16.0   6.0    7.3    13.3
7.53   12   19.5   5.9    5.0    10.9       1

9.56   0    3.9    39.0   0.0    39.0
8.19   0    12.4   32.9   1.2    34.2   1   2
8.62   0    7.1    39.4   0.0    39.4
9.63   0    6.9    37.5   0.0    37.5



8.94   0    9.5    10.8   1.4    12.2

5.32   5    19.4   3.2    5.6    8.9
 5.5   5    18.4   2.4    4.8    7.2



8.99   1    9.6    6.4    7.3    13.8       2
       0    12.2   7.7    8.1    15.8
6.18   1     12    7.57   5.58   13.1       1
8.59   1    9.05   6.9    7.76   14.7           GAMMA-COXY -> EkhgEvC 200


8.49   5    10.7   6.9    6.9    13.7           GAMMA-COXY -> EkhgEvC 200




7.73   0    4.7    5.3    6.0    11.3
4.92   0    3.9    7.0    4.7    11.6   1   1
       1    10.9   8.0    4.0   12.0       1

4.84   10   20.8   4.9    4.4   9.3        1
4.66   8    22.4   5.2    3.4   8.6
4.83   8    20.2   5.8    4.6   10.4       1
4.69   11   20.2   4.9    3.8   8.7
4.52   12   20.7   5.4    4.3   9.8
       14   22.2   3.7    9.9   13.6                                       1
4.58   10   21.3   4.9    3.8   8.7                                        1

5.19   1    11.9   9.0    6.0   14.9   2   2
4.81   0    4.8    7.2    2.4   9.6
6.73   0    9.1    5.7    4.5   10.2
9.35   0    8.1    6.3    4.5   10.8
5.55   0    12.2   9.6    4.3   13.9
5.02   0    13.0   9.6    4.3   13.9       1
9.22   0    8.8    6.1    6.1   12.3   1   1
6.74   0    9.7    8.8    5.3   14.2                                       1
8.47   0    13.6   8.5    2.5   11.0                                       1
8.56   0    13.7   8.5    3.4   12.0
8.78   0    9.6    11.3   6.1   17.4       1
9.08   0    9.0    5.7    4.9   10.7
5.22   0    11.6   9.1    5.0   14.0
5.12   0    13.9   11.3   4.3   15.7                                       2
5.06   0    10.4   10.4   4.3   14.8
6.74   0    10.6   10.6   4.4   15.0                                       1
4.61   0    11.3   8.7    4.3   13.0       1
8.18   0    12.5   9.4    5.5   14.8       1
4.72   0    12.2   12.2   5.2   17.4                                       1
5.23   0    14.0   7.4    4.1   11.6
6.31   0    11.6   9.1    4.1   13.2           GAMMA-COXY -> EvlgEwC 108



6.02   0    13.0   12.2   4.3   16.5                                       2
5.84        11.8                0.0                                        1
8.64   0    5.7    9.8    6.6   16.4
6.72   2    18.8   6.3    5.0   11.3
4.98   1    11.0   5.1    4.4   9.6
6.73   0    8.3    8.3    5.0   13.3
4.81   1    8.8    11.2   6.4   17.6   2   3
4.95   0    9.9    7.7    4.4   12.1
5.73   0    19.0   8.0    2.0   10.0
9.14   0    12.1   7.5    4.7   12.1
8.53   0    11.2   9.3    6.5   15.9
 5.1   0    13.3   8.0    4.0   12.0
 4.9   0    12.5   8.7    1.9   10.6                                       1

4.81   4    17.5   10.2   5.1   15.3
5.37   7    15.9   7.9    7.3   15.2
5.01   4    15.7   4.6    7.8   12.4
4.89   5    17.8   11.7   4.3   16.0
5.09   6    15.5   12.6   5.7   18.4   1   1
5.19   9    20.7   8.6    7.5   16.1       1
4.65   7    16.4   10.3   7.9   18.2
4.48   10   17.6   7.9    8.5   16.4       1
5.55   1    11.5   5.3    9.9   15.3
4.99   9    19.1   8.6    5.9   14.5
5.06   2    18.0   12.0   5.4   17.4



5.58   0    15.5   7.5    1.4   8.9
5.09   0    12.7   7.6    3.3   10.9

5.64   1    18.9   5.3    1.5   6.8        1                               1
5.47    2    18.8   6.0    3.0    9.0        1

4.41    0    10.5   5.7    10.5   16.2   1   2   1
4.31    0    10.5   5.7    10.5   16.2   1   2

3.85    21   23.6   5.5    4.7    10.2
9.39    33   23.3   13.6   11.9   25.6   2   4   1
8.63    20   30.1   3.2    2.2    5.4
6.13    14   20.3   8.4    10.5   18.9       2
5.42    15   20.8   4.8    5.6    10.4
4.06    4    11.4   7.6    12.4   20.0   1   2
3.98    4    11.4   6.7    12.4   19.0   1   2

4.37    3    16.4   6.0    6.9    12.9   1   1   1
4.13    0    10.4   10.4   7.2    17.6       2   1
8.57    1    11.5   10.8   7.7    18.5   2   2   1



3.91    13   23.3   4.5    4.5    9.0
4.29    9    21.8   2.3    4.5    6.8
4.17    6    17.0   0.7    6.7    7.4

4.63    0    10.7   5.2    5.2    10.3           1
4.84    0    12.6   3.7    4.2    7.9

7.19    9    18.0   3.9    2.8    6.7            1
6.43    10   17.7   3.7    2.7    6.5    1   1   1

8.06    0    20.8   2.8    0.0    2.8
4.11    0    17.0   8.0    4.5    12.5       1

5.94    1    10.1   5.0    3.1    8.2
7.66    0    13.3   4.8    4.8    9.5

6.12    0    17.1   9.4    4.3    13.7   1   1   1
8.45    8    14.0   8.9    8.1    17.0   1   3
9.23    0    15.4   9.2    3.7    12.8       1
        0    15.3   3.1    3.1    6.1
5.12    0    21.6   3.7    1.9    5.6            1
8.56    0    10.5   3.2    2.1    5.3
        6    16.1   8.9    8.1    16.9   1   2

 8.2    1    12.7   5.7    5.3    11.0   1   1
4.63    0    10.2   6.1    0.0    6.1
 12     0    18.4   0.0    0.0    0.0
10.03   2    18.9   10.8   16.2   27.0       1
9.69    0    2.7    8.1    2.7    10.8
9.02    0    20.0   2.0    2.0    4.0
11.7    0    9.6    9.6    3.8    13.5
10.77   0    15.4   10.8   7.7    18.5
9.83    1    18.4   8.2    4.1    12.2
12.48   0    15.9   4.5    2.3    6.8    1   1
6.84    0    11.5   3.8    9.6    13.5       1
9.43    0    9.8    6.6    1.6    8.2
6.91    0    5.6    7.4    5.6    13.0
5.36    0    20.0   9.2    4.6    13.8
9.39    0    10.6   10.6   7.6    18.2       1
9.69    0    17.9   4.5    7.5    11.9       1
8.41    3    18.8   1.4    11.6   13.0
10.67   0    13.1   2.4    11.9   14.3
10.9    1    18.7   9.3    6.7    16.0
8.77    0   11.8   5.9    5.9   11.8   1   2
3.91    1   15.2   6.7    3.8   10.5           1
11.21   0   17.2   7.1    4.0   11.1
8.65    0   4.6    9.3    1.9   11.1       1
9.79    2   15.3   4.2    8.5   12.7
10.57   0   5.5    17.3   5.5   22.7
 4.2    0   10.5   1.8    3.5   5.3
8.44    0   13.7   10.3   5.1   15.4   1   1
6.32    0   10.9   9.4    5.1   14.5
4.44    0   5.3    6.9    1.5   8.4
7.71    0   5.5    8.3    6.2   14.5   1   1
10.28   0   9.8    4.6    5.9   10.5
5.81    0   12.0   4.7    5.3   10.0
7.08    2   11.3   15.2   6.6   21.9   3   3
6.13    1   19.9   7.6    5.8   13.5       1
4.78    0   12.4   8.8    7.7   16.5       1
 4.6    1   9.4    8.3    6.3   14.6       1
8.79    1   13.8   6.1    5.6   11.7
9.86        7.3                 0.0    1   2
5.67    0   14.6   7.5    5.7   13.2   2   2   1
5.86    1   12.8   4.1    3.2   7.3
9.47    0   17.4   4.3    4.3   8.5            1
        0   12.8   8.5    2.1   10.7           2
        0   18.5   8.9    2.2   11.1
4.54    0   8.2    6.5    6.5   13.1   1   1   4
4.91    5   15.2   5.3    5.3   10.7       1
11.56   0   5.7    12.3   6.6   18.9   1   2   1
------------------------------------SDS-PAGE RESULTS FROM VALENZUELA ET. AL ISGNV salivary gland homogenate ISSNV saliva sample--------------------------------------------



                                                                                               ISSNV-4
                                                                                              [DNSQTE              ISSNV-6 ISSNV-6B
                                                                                                 HMW]-   ISSNV-5 [NQEHAK [HNAL]-
                                                                                                 [PVL]- [NEHL]-V- ]-[DPV]-      [DV]-                        ISSNV-8b
                                                                ISS4                          [TK]-[EF]- A-[QEH]- [AYK]-       [EPK]-     ISSNV-7            [EH]-[NT]-                                                                                                   ISSNV-12
                                                             [HSQEA]-                           [GA]-G- [EA]-[GA]- [QEH]-A- [QE]-[AV]- [DNSHA]- ISSNV-8        [SP]-                                                                                          ISSNV-11 [DSQTGA
               ISGNV-12                                        [NT]-X-                           [TYK]-   [TPK]-    G-[TK]- G-[TEK]- [QTPV]-         [EHA]- [QRK]-X-                                                                                          [DNGAY]- ]-E-[DV]-T-
               [SQHAM]-                         ISSNV-3      [QK]-X-G-                           [STR]-   [TER]-     [TR]-   [AR]-[NP]- [PIK]- [NT]-[SPI]- G-T-R-P-                                                                                           K-I-P-A-E- [KL]-Y-N-
               [NP]-X-Q-                        E-[PV]-E-     T-R-P-A-                          [DE]-Y- [DNA]-Y- [NAP]-         [AY]-     [SEK]-X- [QERK]-X- A-S-[EQ]-                                                                                        I-Y-[NP]-E- M-Y-[EK]-
                X-G-T-R-                        P-G-X-A-     [SA]-E-E-                        [EAL]-[NI]- [EL]-I-  [AY]-X-I- [SEA]-[EI]- [GY]-[TK]- G-T-R-P- E-N-R-E-                                                                                         V-H-L-V-V- [IV]-P-L-K-
                P-A-S-E-                        Y-Q-V-K-     N-[NR]-E-                         Q-Q-X-N- [QE]-E-Q- [QE]-[EK]- [QE]-[EK]- [RYV]-P- A-S-Q-E- [GE]-X-                                                                                              D-X-A-F- I-Y-X(2)-
                 N-X-R.                          A-G-R.       G-X(2)-Y.                            L.    X-L-X-D. [QR]-X-L.     [QR].   [AS]-[DS]. [NE]-R.     [DY].                                                                                               A.         V.


               ISGNV-12 -> HNcknGTRPtSEenR 21               ISS4 -> HNcKnGTRPtSEENREGcdY 21                                                                                              ISSNV-8 -> HNcKnGTRPtSeENR 21   ISSNV-8B -> HNcKnGTRPtSEENREGcD 21




               ISGNV-12 -> HNcQnGTRPASEenR 21               ISS4 -> HNcQnGTRPASEENREGcdY 21                                  ISSNV6B -> HncQnGTRPASEEnR 21                               ISSNV-8 -> HNcQnGTRPASeENR 21   ISSNV-8B -> HNcQnGTRPASEENREGcD 21




               ISGNV-12 -> HNcQnGTRPASEenR 21               ISS4 -> HNcQnGTRPASEENREGcdY 21                                  ISSNV6B -> HncQnGTRPASEEnR 21                               ISSNV-8 -> HNcQnGTRPASeENR 21   ISSNV-8B -> HNcQnGTRPASEENREGcD 21




               ISGNV-12 -> HNcQnGTRPASEenR 21               ISS4 -> HNcQnGTRPASEENREGcdY 21                                  ISSNV6B -> HncQnGTRPASEEnR 21                               ISSNV-8 -> HNcQnGTRPASeENR 21   ISSNV-8B -> HNcQnGTRPASEENREGcD 21




               ISGNV-12 -> HNcQnGTRPASEknR 21               ISS4 -> HNcQnGTRPASEkNREGcdY 21                                  ISSNV6B -> HncQnGTRPASEknR 21                               ISSNV-8 -> HNcQnGTRPASekNR 21   ISSNV-8B -> HNcQnGTRPASEkNREGcD 21




               ISGNV-12 -> HNcQnGTRPtSEknR 21               ISS4 -> HNcQnGTRPtSEkNREGcdf 21                                                                                              ISSNV-8 -> HNcQnGTRPtSekNR 21   ISSNV-8B -> HNcQnGTRPtSEkNREGcD 21




               ISGNV-12 -> HNcQnGTRPASEenR 21               ISS4 -> HNcQnGTRPASEENREGcdY 21                                  ISSNV6B -> HncQnGTRPASEEnR 21                               ISSNV-8 -> HNcQnGTRPASeENR 21   ISSNV-8B -> HNcQnGTRPASEENREGcD 21




               ISGNV-12 -> HNcknGTRPASEekR 21               ISS4 -> HNcKnGTRPASEEkREGcdY 21                                  ISSNV6B -> HncknGTRPASEEKR 21   ISSNV-7 -> HncKnGTRPAS 21   ISSNV-8 -> HNcKnGTRPASeEkR 21   ISSNV-8B -> HNcKnGTRPASEEkREGcD 21




               ISGNV-12 -> HNcQnGTRPASEqnR 21               ISS4 -> HNcQnGTRPASEqNREGcdY 21                                  ISSNV6B -> HncQnGTRPASEQnR 21                               ISSNV-8 -> HNcQnGTRPASeqNR 21   ISSNV-8B -> HNcQnGTRPASEqNREGcD 21




               ISGNV-12 -> HNcknGTRPASEenR 21               ISS4 -> HNcKnGTRPASEENREGcdY 21                                  ISSNV6B -> HncknGTRPASEEnR 21   ISSNV-7 -> HncKnGTRPAS 21   ISSNV-8 -> HNcKnGTRPASeENR 21   ISSNV-8B -> HNcKnGTRPASEENREGcD 21




               ISGNV-12 -> HNcQnGTRPASEekR 21               ISS4 -> HNcQnGTRPASEEkREGcdY 21                                  ISSNV6B -> HncQnGTRPASEEKR 21                               ISSNV-8 -> HNcQnGTRPASeEkR 21   ISSNV-8B -> HNcQnGTRPASEEkREGcD 21




               ISGNV-12 -> HNcknGTRPASEenR 21               ISS4 -> HNcKnGTRPASEENREGcdY 21                                  ISSNV6B -> HncknGTRPASEEnR 21   ISSNV-7 -> HncKnGTRPAS 21   ISSNV-8 -> HNcKnGTRPASeENR 21   ISSNV-8B -> HNcKnGTRPASEENREGcD 21




               ISGNV-12 -> HNcknGTRPASEenR 21               ISS4 -> HNcKnGTRPASEENREGcdY 21                                  ISSNV6B -> HncknGTRPASEEnR 21   ISSNV-7 -> HncKnGTRPAS 21   ISSNV-8 -> HNcKnGTRPASeENR 21   ISSNV-8B -> HNcKnGTRPASEENREGcD 21




               ISGNV-12 -> HNcknGTRPASEenR 21               ISS4 -> HNcKnGTRPASEENREGcdY 21                                  ISSNV6B -> HncknGTRPASEEnR 21   ISSNV-7 -> HncKnGTRPAS 21   ISSNV-8 -> HNcKnGTRPASeENR 21   ISSNV-8B -> HNcKnGTRPASEENREGcD 21




               ISGNV-12 -> HNcQnGTRPASEenR 21               ISS4 -> HNcQnGTRPASEENREGcdY 21                                  ISSNV6B -> HncQnGTRPASEEnR 21                               ISSNV-8 -> HNcQnGTRPASeENR 21   ISSNV-8B -> HNcQnGTRPASEENREGcD 21




               ISGNV-12 -> HNcknGTRPASEenR 21               ISS4 -> HNcKnGTRPASEENREGcdY 21                                  ISSNV6B -> HncknGTRPASEEnR 21   ISSNV-7 -> HncKnGTRPAS 21   ISSNV-8 -> HNcKnGTRPASeENR 21   ISSNV-8B -> HNcKnGTRPASEENREGcD 21




               ISGNV-12 -> HNcQnGTRPASEknR 21               ISS4 -> HNcQnGTRPASEkNREGcdY 21                                  ISSNV6B -> HncQnGTRPASEknR 21                               ISSNV-8 -> HNcQnGTRPASekNR 21   ISSNV-8B -> HNcQnGTRPASEkNREGcD 21




               ISGNV-12 -> HNcQnGTRPASEenR 21               ISS4 -> HNcQnGTRPASEENREGcdY 21                                  ISSNV6B -> HncQnGTRPASEEnR 21                               ISSNV-8 -> HNcQnGTRPASeENR 21   ISSNV-8B -> HNcQnGTRPASEENREGcD 21




               ISGNV-12 -> HNcknGTRPASEenR 21               ISS4 -> HNcKnGTRPASEENREGcdY 21                                  ISSNV6B -> HncknGTRPASEEnR 21   ISSNV-7 -> HncKnGTRPAS 21   ISSNV-8 -> HNcKnGTRPASeENR 21   ISSNV-8B -> HNcKnGTRPASEENREGcD 21




               ISGNV-12 -> HNcQnGTRPASEqdR 21               ISS4 -> HNcQnGTRPASEqdREGcdY 21                                  ISSNV6B -> HncQnGTRPASEQdR 21                               ISSNV-8 -> HNcQnGTRPASeqdR 21   ISSNV-8B -> HNcQnGTRPASEqdREGcD 21




               ISGNV-12 -> HNcQnGTRPASEqnR 22               ISS4 -> HNcQnGTRPASEqNREGcdY 22                                  ISSNV6B -> HncQnGTRPASEQnR 22                               ISSNV-8 -> HNcQnGTRPASeqNR 22   ISSNV-8B -> HNcQnGTRPASEqNREGcD 22




                                                            ISS4 -> ETcrnGTRPASqtdREGcdY 21                                                                                              ISSNV-8 -> ETcRnGTRPASQtdR 21   ISSNV-8B -> ETcRnGTRPASQtdREGcD 21




                                                            ISS4 -> ETcrnGTRPASqtdREGcdY 21                                                                                              ISSNV-8 -> ETcRnGTRPASQtdR 21   ISSNV-8B -> ETcRnGTRPASQtdREGcD 21




                                                                                                                                                                                         ISSNV-8 -> ETcRnGTRPAtQtdR 21   ISSNV-8B -> ETcRnGTRPAtQtdREGcD 21




                                                            ISS4 -> ETcrnGTRPASqteREGcdY 21                                                                                              ISSNV-8 -> ETcRnGTRPASQtER 21   ISSNV-8B -> ETcRnGTRPASQteREGcD 21




                                                            ISS4 -> ETcrnGTRPASqtqREGcdY 21                                                                                              ISSNV-8 -> ETcRnGTRPASQtqR 21   ISSNV-8B -> ETcRnGTRPASQtqREGcD 21




                                                            ISS4 -> ETcrnGTRPASqtdREGcdY 21                                                                                              ISSNV-8 -> ETcRnGTRPASQtdR 21   ISSNV-8B -> ETcRnGTRPASQtdREGcD 21




                                                            ISS4 -> ETcrnGTRPASqtdREGcdY 21                                                                                              ISSNV-8 -> ETcRnGTRPASQtdR 21   ISSNV-8B -> ETcRnGTRPASQtdREGcD 21




                                                            ISS4 -> ETcrnGTRPASqteREGcdY 21                                                                                              ISSNV-8 -> ETcRnGTRPASQtER 21   ISSNV-8B -> ETcRnGTRPASQteREGcD 21




                                                            ISS4 -> ETcrnGTRPASqtqREGcdY 21                                                                                              ISSNV-8 -> ETcRnGTRPASQtqR 21   ISSNV-8B -> ETcRnGTRPASQtqREGcD 21




                                                            ISS4 -> ETcrnGTRPASqtdREGcdY 21                                                                                              ISSNV-8 -> ETcRnGTRPASQtdR 21   ISSNV-8B -> ETcRnGTRPASQtdREGcD 21




                                                            ISS4 -> ETcrnGTRPASqtdREGcdY 21                                                                                              ISSNV-8 -> ETcRnGTRPASQtdR 21   ISSNV-8B -> ETcRnGTRPASQtdREGcD 21




                                                            ISS4 -> ETcrnGTRPASqtdREGcdY 21                                                                                              ISSNV-8 -> ETcRnGTRPASQtdR 21   ISSNV-8B -> ETcRnGTRPASQtdREGcD 21




                                                            ISS4 -> ETcrnGTRPASqteREGcdY 21                                                                                              ISSNV-8 -> ETcRnGTRPASQtER 21   ISSNV-8B -> ETcRnGTRPASQteREGcD 21




                                                                                                                                                                                         ISSNV-8 -> ETcRnGTRPgSQtqR 21   ISSNV-8B -> ETcRnGTRPgSQtqREGcD 21




                                                            ISS4 -> ETcrnGTRPASqtdREGcdY 21                                                                                              ISSNV-8 -> ETcRnGTRPASQtdR 21   ISSNV-8B -> ETcRnGTRPASQtdREGcD 21




               ISGNV-12 -> SrcnnGTRPASEenR 55               ISS4 -> SrcnnGTRPASEENREGcdY 55                                                                                              ISSNV-8 -> srcnnGTRPASeENR 55   ISSNV-8B -> srcnnGTRPASEENREGcD 55




               ISGNV-12 -> HNcQnGTRPASEenR 21               ISS4 -> HNcQnGTRPASEENREGcdY 21                                  ISSNV6B -> HncQnGTRPASEEnR 21                               ISSNV-8 -> HNcQnGTRPASeENR 21   ISSNV-8B -> HNcQnGTRPASEENREGcD 21




               ISGNV-12 -> HdcQnGTRPASEekR 21               ISS4 -> HdcQnGTRPASEEkREGydY 21                                  ISSNV6B -> HDcQnGTRPASEEKR 21                               ISSNV-8 -> HdcQnGTRPASeEkR 21   ISSNV-8B -> HdcQnGTRPASEEkREGyD 21




               ISGNV-12 -> HdcQnGTRPASEekR 15               ISS4 -> HdcQnGTRPASEEkREGcdY 15                                  ISSNV6B -> HDcQnGTRPASEEKR 15                               ISSNV-8 -> HdcQnGTRPASeEkR 15   ISSNV-8B -> HdcQnGTRPASEEkREGcD 15
ISGNV-12 -> HdcQnGTRPASEekR 21   ISS4 -> HdcQnGTRPASEEkREGcdY 21   ISSNV6B -> HDcQnGTRPASEEKR 21                               ISSNV-8 -> HdcQnGTRPASeEkR 21   ISSNV-8B -> HdcQnGTRPASEEkREGcD 21




ISGNV-12 -> HdcQnGTRPASEekR 21   ISS4 -> HdcQnGTRPASEEkREGcdY 21   ISSNV6B -> HDcQnGTRPASEEKR 21                               ISSNV-8 -> HdcQnGTRPASeEkR 21   ISSNV-8B -> HdcQnGTRPASEEkREGcD 21




ISGNV-12 -> HdcQnGTRPASEekR 21   ISS4 -> HdcQnGTRPASEEkREGcdY 21   ISSNV6B -> HDcQnGTRPASEEKR 21                               ISSNV-8 -> HdcQnGTRPASeEkR 21   ISSNV-8B -> HdcQnGTRPASEEkREGcD 21




ISGNV-12 -> HNcQnGTRPASEekR 21   ISS4 -> HNcQnGTRPASEEkREGcdY 21   ISSNV6B -> HncQnGTRPASEEKR 21                               ISSNV-8 -> HNcQnGTRPASeEkR 21   ISSNV-8B -> HNcQnGTRPASEEkREGcD 21




ISGNV-12 -> HNcQnGTRPASEekR 21   ISS4 -> HNcQnGTRPASEEkREGcdY 21   ISSNV6B -> HncQnGTRPASEEKR 21                               ISSNV-8 -> HNcQnGTRPASeEkR 21   ISSNV-8B -> HNcQnGTRPASEEkREGcD 21




ISGNV-12 -> HdcQnGTRPASEenR 21   ISS4 -> HdcQnGTRPASEENREGcdY 21   ISSNV6B -> HDcQnGTRPASEEnR 21                               ISSNV-8 -> HdcQnGTRPASeENR 21   ISSNV-8B -> HdcQnGTRPASEENREGcD 21




ISGNV-12 -> HNcQnGTRPASEekR 21   ISS4 -> HNcQnGTRPASEEkREGcdY 21   ISSNV6B -> HncQnGTRPASEEKR 21                               ISSNV-8 -> HNcQnGTRPASeEkR 21   ISSNV-8B -> HNcQnGTRPASEEkREGcD 21




ISGNV-12 -> HNcQnGTRPASEekR 21   ISS4 -> HNcQnGTRPASEEkREGcdY 21   ISSNV6B -> HncQnGTRPASEEKR 21                               ISSNV-8 -> HNcQnGTRPASeEkR 21   ISSNV-8B -> HNcQnGTRPASEEkREGcD 21




ISGNV-12 -> HNcQnGTRPASEenR 21   ISS4 -> HNcQnGTRPASEENREGcdY 21   ISSNV6B -> HncQnGTRPASEEnR 21                               ISSNV-8 -> HNcQnGTRPASeENR 21   ISSNV-8B -> HNcQnGTRPASEENREGcD 21




ISGNV-12 -> HNcknGTRPASEenR 21   ISS4 -> HNcKnGTRPASEENREGcdY 21   ISSNV6B -> HncknGTRPASEEnR 21   ISSNV-7 -> HncKnGTRPAS 21   ISSNV-8 -> HNcKnGTRPASeENR 21   ISSNV-8B -> HNcKnGTRPASEENREGcD 21
ISSNV-3 -> EPdPGqpwQVKAGR 22




                               ISSNV-4 -> NVeEAGKTErqIQagsL 18




                               ISSNV-4 -> NVKEAGKTDYEIQeqsL 18   ISSNV5 -> NVkEAGKTDYEIQEQsLli 18   ISSNV-6 -> NVKEAGKTdYeIQEQsL 18   ISSNV6B -> NVKEAGKtdYEIQEQ 18




                               ISSNV-4 -> NVKEAGKTnYEIQeqsL 18   ISSNV5 -> NVkEAGKTNYEIQEQsLli 18   ISSNV-6 -> NVKEAGKTNYeIQEQsL 18   ISSNV6B -> NVKEAGKtNYEIQEQ 18




                               ISSNV-4 -> NVeEAGKSsYqIQkqsL 18                                      ISSNV-6 -> NVeEAGKssYqIQKQsL 18   ISSNV6B -> NVEEAGKssYqIQKQ 18




                               ISSNV-4 -> NVKEAGKSnYEIQegsL 18   ISSNV5 -> NVkEAGKsNYEIQEgsLli 18   ISSNV-6 -> NVKEAGKsNYeIQEgsL 18   ISSNV6B -> NVKEAGKsNYEIQEg 18




                                                                                                                                                                                                             ISSNV-12 -> AaDTKYpMYqIPtqIYpeV 71



                                                                                                                                                                      ISSNV-11 -> YKIPlEIYPEVHLVVDstFA 169   ISSNV-12 -> TgsTKhsMYKIPLeIYpeV 161




                                                                                                                                                                      ISSNV-11 -> YKIPlEIYPEVHLVVDstFA 169   ISSNV-12 -> TgsTKhsMYKIPLeIYpeV 161
ISSNV-11 -> YKIPAEIYPEVHLVVDsAFA 48   ISSNV-12 -> AgsTepqMYKIPaeIYpeV 40
ISSNV-4 -> TgvFGGYSErANhQaNp 19
ple-------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------




                                                                                                   BASIC                                                                                                                                                 Basic tail
                                                                   PROLINE                          TAIL                                                                                                 Basic tail                                        coxy K Basic tail
                                                                   GLYCINE                       PEPTIDE                                                                                                 carboxy                                            rich 1   coxy K
                                ISSNV-                                RICH                       FAMILY -                                                                                                motif F-F-                                      [EK]-P-K- rich 2 E-K-                                                         THROMB
                                  13B                              PEPTIDE                       AMINOTE                        Basic tail                                                               X(3)-E-X-                                        Q-K-K-K- P-[RK]-K- IXOSTATI                                                  OSPONDI
                     ISSNV-13 [NSKL]-               ISSNV-14       S motif G-                     RMINAL                         cysteine                                                                 C-F-Y-                                          K-[TLPQ]- [SN]-K-K- N motif L-                                                 N CYS
                      [SK]-E-    [TEP]-               [SWF]-        [SKQN]-          GPP         REGION                         framewor                                                                  X(2)-G-                                            K-K-   K-[SQ]-K- X-D-G-T-                                                 DOMAIN
                       [DPV]-    [DPV]-             [EP]-[DV]-     [ST]-X-P-       Platelet      A-A-X(2)-                      k C-X(14)-                                                               X(2)-G-X-                                        [TNPA]-K- K-[ST]-K- X-C-G-                                                   C-X(11)-C-
                     [QG]-L-E- [QG]-L-E-             G-L-E-Q-      C-X(3)-P-       collagen      C-X-N-G-                       C-X(3)-C-                                                                C-X(2)-G-                                        K-P-K-R- K-P-K-K- X(4)-C-                                                     X(14)-C-
                      Q-Y-X-R- Q-Y-X-K-             Y-[PV]-X-      G-X(2)-C-       binding       T-R-P-X-                        X(18)-C-                                                                X-C-H-L-                                        [KN]-[ST]- [ST]-K-K- X(2)-G-X-                                                 X(3)-C-
                       V-E-D.      V.                  V-E.          X(8)-P.       domain            S.                           X(9)-C.                                                                 X(6)-P                                             K-K.       P.     C-X(7)-F.                                                X(24)-C.


                                                                                                 BT-NH2 -> AAhnCkNGTRPtS 19   BT-CY S -> CkngtrptseenregCdy y Cwnev tsswdqf f f gngerCf y ntgengrC 23   BT-COXY -> FFgngErCFYntGenGrCqnGeCHLttssggP 54   BTSP-K1 -> KPKQKKKKPKKNKKPKRKSrK 98




                                                                                                 BT-NH2 -> AAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseenregCdy y Cwndv tnswdqf f f gngerCf y ntgengkC 23   BT-COXY -> FFgngErCFYntGenGkClnGeCHLttssggP 54   BTSP-K1 -> KPKQKKKKPKKPKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseenregCdy y Cwnev tnswdqf f f gngerCf y ntgengkC 23   BT-COXY -> FFgngErCFYntGenGkCqnGeCHLttnsdgP 54   BTSP-K1 -> KPKQKKKKPKKPKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseenregCdy y Cwntdtnswdqf f f gngekCf y ntgekgtC 23    BT-COXY -> FFgngEkCFYntGekGtClnGeCHLttssggP 54   BTSP-K1 -> KPKQKKKKPKKTKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseknregCdy y Cwnaetklwdqf f f gngekCf y ntgdrgiC 23    BT-COXY -> FFgngEkCFYntGdrGiCqnGeCHLttssggP 54   BTSP-K1 -> KPKQKKKKPKKTKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCqNGTRPtS 19   BT-CYS -> CqngtrptseknregCdfyCwnadtnlwdkfffgngekCfyntgekgtC 23            BT-COXY -> FFgngEkCFYntGekGtClnGeCHLttssggP 54   BTSP-K1 -> KPKQKKKKPKKTKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseenregCdy y Cwnaetkswdqf f f gngerCf y ntgekgtC 23    BT-COXY -> FFgngErCFYntGekGtClnGeCHLttssggP 54   BTSP-K1 -> KPKQKKKKPKKTKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCkNGTRPaS 19   BT-CY S -> CkngtrpaseekregCdy y Cwntetkswdkf f f gngerCf y stgengkC 23    BT-COXY -> FFgngErCFYstGenGkCqnGeCHLttssggP 54   BTSP-K1 -> KPKQKKKKPKKTKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseqnregCdy y Cwnaetkswdqf f f gngekCf y nsgdrgtC 23    BT-COXY -> FFgngEkCFYnsGdrGtCqnGeCHLttnsggP 54   BTSP-K1 -> KPKQKKKKTKKTKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCkNGTRPaS 19   BT-CY S -> CkngtrpaseenregCdy y Cwnev tnswdqf f f gngerCf y ntgengkC 23   BT-COXY -> FFgngErCFYntGenGkCqnGeCHLttnsggP 54   BTSP-K1 -> KPKQKKKKPKKPKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseekregCdy y Cwntetkswdkf f f gngerCf y nsgdhgtC 23    BT-COXY -> FFgngErCFYnsGdhGtCqnGeCHLtnnsggP 54   BTSP-K1 -> KPKQKKKKTKKTKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCkNGTRPaS 19   BT-CY S -> CkngtrpaseenregCdy y Cwnev tsswdqf f f gngerCf y ntgengkC 23   BT-COXY -> FFgngErCFYntGenGkClnGeCHLttnsggP 54   BTSP-K1 -> KPKQKKKKPKKNKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCkNGTRPaS 19   BT-CY S -> CkngtrpaseenregCdy y Cwnev tnswdqf f f gngerCf y ntgengkC 23   BT-COXY -> FFgngErCFYntGenGkCqnGeCHLttnsdgP 54   BTSP-K1 -> KPKQKKKKPKKPKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCkNGTRPaS 19   BT-CY S -> CkngtrpaseenregCdy y Cwndgtnswdqf f f gngeiCf y nsgekgiC 23    BT-COXY -> FFgngEiCFYnsGekGiCqnGeCHLtnnsggP 54   BTSP-K1 -> KPKQKKKKPKKPKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseenregCdy y Cwnaetxswdqy f f gngerCf y nsgekgtC 23    BT-COXY -> FFgngErCFYnsGekGtClnGeCHLttssggP 54   BTSP-K1 -> KPKQKKKKPKKTKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCkNGTRPaS 19   BT-CY S -> CkngtrpaseenregCdy y Cwntv tsswdqf f f gngerCf y ntgengkC 23   BT-COXY -> FFgngErCFYntGenGkCinGeCHLttnsggP 54   BTSP-K1 -> KPKQKKKKPKKTKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseknregCdy y Cwnaetkswdqf f f gdgerCf y ntgengtC 23    BT-COXY -> FFgdgErCFYntGenGtCrnGeCHLttssggP 54   BTSP-K1 -> KPKQKKKKPKKTKKPKRKSrK 98




                                                                                                 BT-NH2 -> AAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseenregCdy y Cwnsgtnlwdqf f f gngekCf y ntgekgiC 23    BT-COXY -> FFgngEkCFYntGekGiCqnGeCHLttnsggP 54   BTSP-K1 -> KPKQKKKKTeKTKKPKRKSrK 98




                                                                                                 BT-NH2 -> AAhnCkNGTRPaS 19   BT-CY S -> CkngtrpaseenregCdy y Cwndgtnswdqf f f gngeiCf y nsgekgiC 23    BT-COXY -> FFgngEiCFYnsGekGiCqnGeCHLtnnsggP 54   BTSP-K1 -> KPKQKKKKTKKPKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseqdregCdy y Cwnaetkswdqf f f gngekCf y nsgdhgtC 23    BT-COXY -> FFgngEkCFYnsGdhGtCqnGeCHLtnnsggP 54   BTSP-K1 -> KPKQKKKKTKKTKKPKRKSKK 98




                                                                                                 BT-NH2 -> AAhnCqNGTRPaS 20   BT-CY S -> CqngtrpaseqnregCdy y Cwnaetkswdqf f f gngekCf y nsgdrgtC 24    BT-COXY -> FFgngEkCFYnsGdrGtCqnGeCHLtttsggP 55   BTSP-K1 -> KPKQKKKKTKKTKKPKRKSKK 99




                                                                                                 BT-NH2 -> AAetCrNGTRPaS 19   BT-CYS -> CrngtrpasqtdregCdyyCwntltsswdkyffgdeepCfyntglkgtC 23            BT-COXY -> FFgdeEpCFYntGlkGtCknGeCHLtseggvP 54                                          BTSP-K2 -> EKPKKNKKKSKKTKKPKKSKKP 97




                                                                                                 BT-NH2 -> AAetCrNGTRPaS 19   BT-CYS -> CrngtrpasqtdregCdyyCwntltsswdkyffgdeepCfyntglrgtC 23            BT-COXY -> FFgdeEpCFYntGlrGtCknGeCHLtseggvP 54                                          BTSP-K2 -> EKPKKNKKKSKKTKKPKKSKKP 97




                                                                                                 BT-NH2 -> AAetCrNGTRPat 19   BT-CYS -> CrngtrpatqtdregCdyyCwntltsswdkyffgdeepCfyntglkgtC 23            BT-COXY -> FFgdeEpCFYntGlkGtCknGeCHLtseggvP 54                                          BTSP-K2 -> EKPKKNKKKSKKTKKPKKSKKP 97




                                                                                                 BT-NH2 -> AAetCrNGTRPaS 19   BT-CYS -> CrngtrpasqteregCdyyCwnsetsswdkyffgdnepCfyntglrgtC 23            BT-COXY -> FFgdnEpCFYntGlrGtCknGeCHLtsegsvP 54                                          BTSP-K2 -> EKPKKNKKKSKKTKKPKKTKKa 97




                                                                                                 BT-NH2 -> AAetCrNGTRPaS 19   BT-CYS -> CrngtrpasqtqregCdyyCwnlqtsswdkyffgdnepCfyntglrgtC 23            BT-COXY -> FFgdnEpCFYntGlrGtCqnGeCHLtseggvP 54                                          BTSP-K2 -> EKPKKNKKKSKKTKKPKKTKKP 97




                                                                                                 BT-NH2 -> AAetCrNGTRPaS 19   BT-CYS -> CrngtrpasqtdregCdyyCwntltsswdkyffgdeepCfyntglkgtC 23            BT-COXY -> FFgdeEpCFYntGlkGtCknGeCHLtseggvP 54                                          BTSP-K2 -> EKPKKNKKKSKKTKKPKKTKKP 97




                                                                                                 BT-NH2 -> AAetCrNGTRPaS 19   BT-CYS -> CrngtrpasqtdregCdyyCwntltsswdkyffgdeepCfyntglrgtC 23            BT-COXY -> FFgdeEpCFYntGlrGtCknGeCHLtsegnvP 54                                          BTSP-K2 -> EKPKKSKKKSKKTKKPKKTKKP 97




                                                                                                 BT-NH2 -> AAetCrNGTRPaS 19   BT-CYS -> CrngtrpasqteregCdyyCwntetrswdkyffgdnepCfyntglkgtC 23            BT-COXY -> FFgdnEpCFYntGlkGtCknGeCHLtsegnlP 54                                          BTSP-K2 -> EKPKKSKKKSKKTKKPKKTKKt 97




                                                                                                 BT-NH2 -> AAetCrNGTRPaS 19   BT-CYS -> CrngtrpasqtqregCdyyCwnsqtsswdkyffgdnepCfyntglrgtC 23            BT-COXY -> FFgdnEpCFYntGlrGtCqnGeCHLtseggvP 54                                          BTSP-K2 -> EKPRKNKKKSKKTKKPKKSKKP 97




                                                                                                 BT-NH2 -> AAetCrNGTRPaS 19   BT-CYS -> CrngtrpasqtdregCdyyCwntltsswdkyffgdeepCfyntglkgtC 23            BT-COXY -> FFgdeEpCFYntGlkGtCknGeCHLtseggvP 54                                          BTSP-K2 -> EKPKKNKKKSKKTKKPKKSKKP 97




                                                                                                 BT-NH2 -> AAetCrNGTRPaS 19   BT-CYS -> CrngtrpasqtdregCdyyCwnsltsswdkyffgdeepCfyntglkgtC 23            BT-COXY -> FFgdeEpCFYntGlkGtCknGeCHLtseggvP 54                                          BTSP-K2 -> EKPKKNKKKSKKTKKPKKSKKP 97




                                                                                                 BT-NH2 -> AAetCrNGTRPaS 19   BT-CYS -> CrngtrpasqtdregCdyyCwntltsswdkyffgdqepCfyntglkgtC 23            BT-COXY -> FFgdqEpCFYntGlkGtCknGeCHLtseggvP 54                                          BTSP-K2 -> EKPKKNKKKSKKTKKPKKTKKP 97




                                                                                                 BT-NH2 -> AAetCrNGTRPaS 19   BT-CYS -> CrngtrpasqteregCdyyCwntqtsswdkyffgdnepCfyntglkgtC 23            BT-COXY -> FFgdnEpCFYntGlkGtCqnGeCHLtndggvP 54                                          BTSP-K2 -> EKPKKNKKKSKKTKKPKKTKKP 97




                                                                                                 BT-NH2 -> AAetCrNGTRPgS 19   BT-CYS -> CrngtrpgsqtqregCdyyCwnsqtsswdkyffgdnepCfyntglrgtC 23            BT-COXY -> FFgdnEpCFYntGlrGtCqnGeCHLtseggvP 54                                          BTSP-K2 -> EKPKKNKKKSKKTKKPKKTKKP 97




                                                                                                 BT-NH2 -> AAetCrNGTRPaS 19   BT-CYS -> CrngtrpasqtdregCdyyCwntltsswdkyffgdeepCfyntglrgtC 23            BT-COXY -> FFgdeEpCFYntGlrGtCknGgCHLtsegnvP 54                                          BTSP-K2 -> EKPKKSKKKSKKTKKPKKTKKP 97




                                                                                                                              BT-CY S -> ssecpdirrrpqdtnCny y Crnqddngweegf lldgetCny v tendgv C 19




                                                                                                 BT-NH2 -> scsrCnNGTRPaS 53   BT-CY S -> CnngtrpaseenregCdy y Cwnev tnswdqf f f gngerCf y ntgengkC 57   BT-COXY -> FFgngErCFYntGenGkCqnGeCHLttnsggP 88   BTSP-K1 -> KPKQKKKKPKKAKKPKRKSKK 132




                                                                                                                              BT-CY S -> sskcpdikrrqqdtnCny y Cpnqagdgwdegf lldgetCny laendgv C 19




                                                                                                                              BT-CY S -> stkcpdikrrqqdtnCny y Cpnqagdgwdegf lldgetCny laendgv C 19




                                                                                                 BT-NH2 -> AAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseenregCdy y Cwnsetqswdqy f f gdgerCf y nsgdrgiC 23    BT-COXY -> FFgdgErCFYnsGdrGiCqnGeCHLttssggP 54   BTSP-K1 -> KPKQKKKKPKKTKePKRKSKK 98




                                                                                                 BT-NH2 -> AAhdCqNGTRPaS 19   BT-CY S -> Cqngtrpaseekregy dy y Cwntetkswdkf f f gngerCf y nngdeglC 23   BT-COXY -> FFgngErCFYnnGdeGlCqnGeCHLttdsgvP 54




                                                                                                 BT-NH2 -> AAhdCqNGTRPaS 13   BT-CY S -> CqngtrpaseekregCdy y Cwntetkswdkf f f gngerCf y nngdeglC 17    BT-COXY -> FFgngErCFYnnGdeGlCqnGeCHLttdsgvP 48
BT-NH2 -> AAhdCqNGTRPaS 19   BT-CY S -> CqngtrpaseekregCdy y Cwntetkswdkf f f gngerCf y nngdeglC 23    BT-COXY -> FFgngErCFYnnGdeGlCqnGeCHLttdsgvP 54




BT-NH2 -> AAhdCqNGTRPaS 19   BT-CY S -> CqngtrpaseekregCdy y Cwneetkswdkf f f gngerCf y ndggeglC 23    BT-COXY -> FFgngErCFYndGgeGlCqdGeCHLntdssvP 54




BT-NH2 -> AAhdCqNGTRPaS 19   BT-CY S -> CqngtrpaseekregCdy y Cwneetkswdkf f f gngerCf y ndgaeglC 23    BT-COXY -> FFgngErCFYndGaeGlCqnGeCHLttdsevP 54




BT-NH2 -> AAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseekregCdy y Cwnaetnswdkf f f gngerCf y sdgseglC 23    BT-COXY -> FFgngErCFYsdGseGlCqnGeCHLttdssvP 54




BT-NH2 -> AAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseekregCdy y Cwnaetkswdkf f f gngerCf y ndggegqC 23    BT-COXY -> FFgngErCFYndGgeGqCqnGeCHLttdssvP 54




BT-NH2 -> vAhdCqNGTRPaS 19   BT-CY S -> CqngtrpaseenregCdy y Cwntetkswdkf f f gngerCf y ndggeglC 23    BT-COXY -> FFgngErCFYndGgeGlCqnGeCHLttdssvP 54




BT-NH2 -> vAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseekregCdy y Cwnaetnswdkf f f gngerCf y ndggeglC 23    BT-COXY -> FFgngErCFYndGgeGlCqnGeCHLttdssvP 54




BT-NH2 -> vAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseekregCdy y Cwnaetnswdkf f f gngerCf y ndggeglC 23    BT-COXY -> FFgngErCFYndGgeGlCqnGeCHLttdssvP 54




BT-NH2 -> vAhnCqNGTRPaS 19   BT-CY S -> CqngtrpaseenregCdy y Cwnaetkswdqf f f gngerCf y ndggeglC 23    BT-COXY -> FFgngErCFYndGgeGlCqnGeCHLttdssvP 54




                             BT-CYS -> CctasardvnllsclparkCnvpeingwiskvvcrefcCrvcciysrpC 13




BT-NH2 -> AAhnCkNGTRPaS 19   BT-CY S -> CkngtrpaseenregCdy y Cwnev tnswdqf f f gngerCf y ntgengkC 23   BT-COXY -> FFgngErCFYntGenGkCqnGeCHLttnsdgP 54
                                    GPP-> GPP 43




                                    GPP-> GPP 41
                                    GPP-> GPP 41




PRP -> GSStPCpgaPGqpCnplqgsqgP 22



PRP -> GSTtPCpgaPGeaCnpgngpqgP 22




PRP -> GSStPCpgaPGedCspgsglqgP 22



PRP -> GSTtPCpgaPGqpCdsgpgpqgP 23




PRP -> GSStPCpgaPGepCqngqpsqpP 22




PRP -> GNStPCpvaPGqdCnpgngpqgP 22




PRP -> GSTtPCpgaPGevCnpgngpqgP 22




PRP -> GSTtPCpgaPGqpCnplqgsqgP 22



PRP -> GSTtPCpgaPGeaCnpgngpqgP 22




PRP -> GSStPCpngPGqpCgpgqnpqgP 22   GPP-> GPP 43
PRP -> GSStPCpnpPGqgCapgqnpqgP 22   GPP-> GPP 43
PRP -> GSStPCpgaPGqdCssggglqgP 22




                                    GPP-> GPP 44
                                    GPP-> GPP 56
PRP -> GSStPCpngPGqpCapgqnpqgs 22




PRP -> GSptPCpnpPGqpCtpgqrpqgr 22



PRP -> GSStPCptaPGedCnpgsrlqgP 22



PRP -> GSTtPCpgaPGegChpgdglqgP 22




PRP -> GSTtPCpgaPGeaCspgnnpqgP 22




                                    GPP-> GPP 59


PRP -> GSptPCpnpPGepCtpgkgpqgP 43



PRP -> GSStPCtspPGepCppgqgpqgP 22




PRP -> GNStPCsnpPGtpCgpgqdpqdP 22



                                    GPP-> GPP 63
                                    GPP-> GPP 57
PRP -> GSStPCpgaPGqeCspggdlqgP 22
PRP -> GSStPCpgaPGqeCspggdlqgP 22




PRP -> GSStPCpkaPGqpCgpgqnpqgP 22   GPP-> GPP 43


                                    GPP-> GPP 22
PRP -> GSStPCptaPGedCrsggglqgP 22



PRP -> GSTtPCpgaPGedCnpgngpqgP 22




PRP -> GSTtPCpgaPGqpCnplqgsqgP 22



PRP -> GSTtPCpgaPGqpCnplqgsqgP 22




PRP -> GSStPCpgaPGepCqngqpsqpP 22




PRP -> GSStPCpgaPGedCnpgsrlqgP 22



PRP -> GSStPCpgaPGepCqngnpsqpP 22




PRP -> GSStPCpgaPGepCqngqpsqpP 22




PRP -> GSStPCpgaPGepCqngnpskpP 22




PRP -> GSStPCpgaPGepCgngnspggP 22




PRP -> GSTtPCpgaPGeaCnpgngpqgP 22




PRP -> GSStPCpgaPGepCgngnspggP 22




PRP -> GSTtPCpgaPGqdChpgngpqgP 22




PRP -> GSStPCptaPGedCnpgsrlqgP 22




                                    GPP-> GPP 47




                                    GPP-> GPP 48




                                                   IXOSTATINS -> vvDGTpCGkkkaCilGkCvddikisk 460




                                                   IXOSTATINS -> vvDGTpCGkkkaCilGkCvddikisk 460
IXOSTATINS -> vvDGTpCGnkkaCilGkCrneikist 339




IXOSTATINS -> LnDGTpCGpnkiCidGqCvsrcsmpF 87    THROMB-CYS -> CkdklktemiqrCsehlyqpllvevleCtfkCgnehnngktiltsgqyiklndgtpC 37




IXOSTATINS -> LkeGTaCGfrkvCigGkCvqqcqvvF 87    THROMB-CYS -> CkndlkeqmerrCsehsyqprllevndCsitCgdwhnngqtrgtssqiihlkegtaC 37




                                               THROMB-CYS -> CksklidevqdkClrtslgstlvefkgCsfvCekiktksgtqeevrvtvnlnddipC 37




IXOSTATINS -> mkDGTpCGhsrvCvsGvCvdtcrmsF 87    THROMB-CYS -> CkhklkeqiqneCsghtyqplvikvtdCtytCgnehenffiqtktnqtfnmkdgtpC 37




IXOSTATINS -> LkDGTpCGhsrvCvkGeCvdtcrmtF 87    THROMB-CYS -> CktnlkeqiqnrCsghkyqplllevkdCkivCgdwhdngvtkattrhtinlkdgtpC 37




IXOSTATINS -> LkDGTpCGqnkvCikGnCvyacgmtF 87    THROMB-CYS -> CkenlkkqiaseCegnqyhptpveftgCqfkCgyendyifvklttrrtinlkdgtpC 37




IXOSTATINS -> LkDGTpCGhsrvCikGeCvdtcqmtF 87    THROMB-CYS -> CknnlkeqiqnkCsghtyqplllevkdCtiiCgdwhdngvtkaktrhtinlkdgtpC 37




                                               THROMB-CYS -> CqteiqyqmkqvCkvhershfipsllgCfvyCyndrsdgmrvplrnglpcgnygqiC 40




IXOSTATINS -> LaDGlpCGpckeCchGvCrpvefgfg 65




                                               THROMB-CYS -> CkteiklqmeqiCkvhdrfkftpsyggCfvyCynnendgmrvtlrnglpcgengqiC 41




IXOSTATINS -> LpDGlpCGkcreCcgGsCtavqfnle 76




IXOSTATINS -> LnDGTpCGpnkiCidGqCvprcsmpF 87    THROMB-CYS -> CkqklrdemeqrCsehpfqpelvevlqCkfkCgnehsngktllisgqyinlndgtpC 37




IXOSTATINS -> LkDGTpCGhsrvCikGkCfdtcqmtF 87    THROMB-CYS -> CkvnikkqiedkCsgnpyqpqllevkdCtiiCgdwhdngvtkaitrhiinlkdgtpC 37




IXOSTATINS -> LkDGTsCGyrkiCvgGhCvqqclvdF 87    THROMB-CYS -> CkdtliqqmrnkCgespfqtqlvevkdCsfaCgewhnngqtmgtsrqttnlkdgtsC 37
                             GPP-> GPP 188




                             GPP-> GPP 183




                             GPP-> GPP 187




ISSV-13A -> KTPQLgsYgKt 20
ISSNV-13 -> SEDGLEQdtkVEt 21   ISSV-13A -> SEDGLEQdtKV 21   ISSNV-14 -> SEDGLEQdtkVE 21



ISSNV-13 -> SEgGLEkdsRVEt 21



ISSNV-13 -> SEgGLEkdsRVEt 21



ISSNV-13 -> SEDGLEQdskVEt 21   ISSV-13A -> SEDGLEQdsKV 21   ISSNV-14 -> SEDGLEQdskVE 21



ISSNV-13 -> SEDGLEQdtiVEt 21   ISSV-13A -> SEDGLEQdtiV 21   ISSNV-14 -> SEDGLEQdtiVE 21




ISSNV-13 -> SEDGLEQdskVEt 21   ISSV-13A -> SEDGLEQdsKV 21   ISSNV-14 -> SEDGLEQdskVE 21




                                                                                          GPP-> GPP 63
GPP-> GPP 29




GPP-> GPP 90
GPP-> GPP 90
GPP-> GPP 91
------------------------------------------------------------------------MOTIFS SEARCHED TO FACILITATE GROUPING OF POLYPEPTIDES--------------------------------------------------------------

                            CONSER
                               VED                                                                                                                         PUT-10
                            CATALYT                                                                                                                       CYSTEIN
                                IC        MONOLA                                                                                                              E
                            DOMAIN          RIS-2                                                                                            MICROPL      FRAMEW
                               OF         CYSTEIN                  MONOLA MONOLA            MONOLA                           RGD               USIN        ORK OF
                             IXODES           E        SALP10         RIS-3     RIS-4          RIS-5   MONOLA               peptide             CYS       PUTATIV
                   SCO-     METALL        FRAMEW       motif L-     cysteine cysteine        Cysteine RIS-6 cys MONOLA        cys            FRAMEW       E 10 KDA
                 PONDIN OPROTE             ORK C-       X(3)-C-    framewor framewor        framewor framewor RIS-7 C- framewor               ORK C-      PEPTIDE
                 C-X(14)-C- ASES H-        X(5)-C-      X(2)-P-     k C-X(8)- k C-X(10)-     k C-X(8)- k C-X(8)- X(8)-C- k C-X(4)-            X(12)-C-    C-X(11)-C-
                  X(3)-C- E-L-A-H-         X(15)-C-    X(2)-C-X-   C-X(15)-C- C-X(3)-C-     C-X(18)-C- C-X(18)-C- X(16)-C- C-X(5)-C-          X(21)-C-     X(15)-C-
                  X(22)-C- N-L-G-C-        X(8)-C-     G-X(6)-Y-     X(7)-C-   X(23)-C-       X(5)-C-   X(5)-C-   X(5)-C- X(5)-C-X-           X(4)-C-      X(3)-C-
                  X(6)-C- Q-H-D-G-         X(11)-C-    Y-X(4)-G-    X(12)-C- X(10)-C-        X(12)-C- X(11)-C- X(11)-C-C- C-X(11)-            X(5)-C-      X(12)-C-
                  X(4)-C.       D.         X(3)-C.        C.         X(3)-C.    X(4)-C.       X(3)-C.   X(3)-C.   X(3)-C.      C.             X(25)-C.     X(6)-C.
MONOLARIS-2 -> Cv kpv dCpgnekev sf y dprrgCqlirlgenCthndny ptldlCnehC 37   SALP10 -> LdprCvkPvdCpGnekevsfYdprrGC 33




MONOLARIS-2 -> Cv kpreCpgtsqtv sy y npeagCqliqlganCtdngny ktlgeCnkhC 37    SALP10 -> LdpkCvkPreCpGtsqtvsYYnpeaGC 33




MONOLARIS-2 -> Cv kpreCpgtsqtv sy y npeagCqliqlganCtdngny ktlgeCnkhC 37    SALP10 -> LdpkCvkPreCpGtsqtvsYYnpeaGC 33




MONOLARIS-2 -> Cv kpkgCpgdf ktv sy y dpnkgCqliklgenCtdngny ptledCnrhC 37   SALP10 -> LnpkCvkPkgCpGdfktvsYYdpnkGC 33




MONOLARIS-2 -> CvkpkeCpgnsktvyyydpksgCqhiqlgadCtdngnyrtlaeCnqyC 37         SALP10 -> LngrCvkPkeCpGnsktvyYYdpksGC 33




MONOLARIS-2 -> CekpndCpgnqrtv f y y nrtagCqqirlgagCsdngny qtleeClknC 35    SALP10 -> LnprCekPndCpGnqrtvfYYnrtaGC 31




MONOLARIS-2 -> CekpndCpgnqrtv f y y nrtagCqqirlgagCsdngny qtldeCltkC 35    SALP10 -> LnprCekPndCpGnqrtvfYYnrtaGC 31




MONOLARIS-2 -> Cekpkv Cpgnnrtv y y y nrrggCksitlgadCtdngny etlreCqqnC 37   SALP10 -> LnpkCekPkvCpGnnrtvyYYnrrgGC 33




MONOLARIS-2 -> CekpkeCpgsdrtvyyynrkegCkgvqlgknCtdngnydslelCntyC 37         SALP10 -> LnpkCekPkeCpGsdrtvyYYnrkeGC 33




MONOLARIS-2 -> CekpkeCpgsdrtvyyynrkegCkgvqlgknCtdngnydslelCntyC 37         SALP10 -> LnpkCekPkeCpGsdrtvyYYnrkeGC 33




MONOLARIS-2 -> CekpkeCpgnsktvyyydpksgCqhiqlgadCtdngnyrtlaeCnqyC 37         SALP10 -> LnpkCekPkeCpGnsktvyYYdpksGC 33




MONOLARIS-2 -> CekpkeCpgkdrtvyyynpkqgCrgvqlgknCtdngnyhslelCnryC 37         SALP10 -> LdpkCekPkeCpGkdrtvyYYnpkqGC 33




                                                                                                                      KUN-ANCY -> CymkpktgpCkakyerfhydrkdltCkpfiyggCggnennfktkeeCqkaC 30




                                                                                                                      KUN-ANCY -> CtlpkktgpCkasf srf y f dnkdgqCksf ty ggCggngnnf ktlkkCqrtC 30




                                                                                                                      KUN-ANCY -> CrspyavtmCeegslkyiysfdnntnqcvsyqgCgtgknifdsyekClgeC 25




                                                                                                                      KUN-ANCY -> CrgllasssCahgstrtiy sf lnatnrcqsy dgCdqgpnrf dsy geCitkC 25




                                                                                                                      KUN-ANCY -> Craqlaf ssCeanstrv f y sf f nntnqcesy tgCdtgknrf pslgkCineC 25




                                                                                                                      KUN-ANCY -> CraphpissCapgavketwyfnnrtnkcekysgCgkgmndfgtracCkdsC 25




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CraprpqtiCgndvnvtlqhyfnnntgkCekengCnkgpnnfpteekCqeeC 24




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CraprpqsiCgndvnvtlqhyfsnntgkCeketgCnkgpnnfptkekCqeeC 24




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CraprpfasCsgnaplrtfyyfsnytnqCehsfgCdmglntfedkvcCateC 25




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CraphpvssCasgtpittmyyfdnhtdrCqnylgCgggyndfgslgcCmdsC 25




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CraphavasCaadikpkllfyfnngtnrCesyygCggglndfgskacCkdsC 25




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CraphavasCaadikpkllfyfnngtnrCesyygCggglndfgskacCkdsC 25




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CraphassiCatgttpkttyyfnngtdqCesefgCasgpydfptlekCkenC 24




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CeaprafasCasdvtpvtlyyynnhtgkCekdfgCgngpnnfptegvCkseC 24




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CeaphptpsCdgqaplrtsyyfnngtgkCeseigCsngttdfssegdCkraC 24




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CeaphptpsCdgqaplrtsyyfnngtgkCesefgCsngrtdfsseedCrqaw 24




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CeaphptphCddqaplrityyfnngtgkCesqfgCsngptdfsseedCrgaC 24




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CeaphpesiCapdvaprytyyynnhtgqCeqtfgCgggrndfpniedCqneC 25




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CeaphatpqCapnatlqttyyynngtgkCegeygCgngendfstedeCrreC 26




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CeaphasslCapgvpledtyyynngtlqCekdfgCekrgnnfpsleeCkneC 24




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CeaphampqCapgvtprvtyyfnngtgrCesdygCgngrndfptaekCrdaC 24




                                                                                                                                                                                                                                                                                MONOLARIS-5 -> CeaphampqCapdvpprvtyyfnngtgrCesdygCgsgqndfatakeCrdaC 24




                                                                                                                                                                                                                                                                                                                                                         MONOLARIS-6 -> CeapyatpqCapgstlgdfyyynngtqkCekefsCpgprnfpsegqCrkeC 24




                                                                                                                                                                                                                                                                                                                                                         MONOLARIS-6 -> CeapyatayCasdaelrdffyfyngtgkCeielgCrgpmnypteeeCikaC 24




                                                                                                                                                                                                                                                                                                                                                         MONOLARIS-6 -> CeapyasasCgsdaelgdffyfhngtgrCvsefgChgpmnyptedeCrrqC 24




                                                                                                                                                                                                                                                                                                                                                         MONOLARIS-6 -> CeaphatpqCapgstlgnfyyynngtqrCekeftCpgprnfpskgqCrkeC 24




                                                                                                                                                                                                   MONOLARIS-4 -> CtrkwpvlwppClfiCqhgswglhswpkftlehkqngtpCrrhlglsrgvClngrC 22




                                                                                                                                                                                                   MONOLARIS-4 -> CtrkwpvlwppClfiCqhgswglhswpkftlehkpngtyCrrhlglsrgeCfngrC 22




                                                                                                                                                                                                   MONOLARIS-4 -> CtrkwpvlwppClfiCqhgnwglhswptftlehkpngtpCrrhlglsrgvCmngrC 22
                                                                          CC-7 -> CrrpvpstsCanglrtiyyfsnhtnkCekmqsCgvgvnhfekeeCCeseC 25




                                                                          CC-7 -> Crrpv pstsCasgv rtiy y f snhtnkCekmqsCgv gv nhf ekkkCCeseC 25




KUN-ANCY -> CtrdmkdgpCralikrffynmttgkCeqfwyggCdgnknnfdeenvCnaiC 31




KUN-ANCY -> fcldpdnvtCpengthasynrntsmCelkngsdCgggenhypslekCnssC 43




KUN-ANCY -> Cldpeqv tcesqegthasy nrktgqCeeqkgteCgggenhf etllkCnesC 42




KUN-ANCY -> Cldrdnv tcenksgthasy npltgkCev lv gtdCgggenhf tnmteCnktC 42




KUN-ANCY -> tkcnltktsCpglkekwhf ngligrCerstpsf Cggkdntf pdf keCqrtC 21




KUN-ANCY -> tqcnstkv sCprlkeewhf ngligrCerstrsf Cggndnkf stf eeCqriC 21




KUN-ANCY -> tqcnltktsCprrkqnwhf ny ligrCersttsf Cggkditf ssf eeCqrtC 21




KUN-ANCY -> tqcnlmttsCtrrqkdwhf nhligrCerstssf Cggkgntf skf eeCqqtC 21




KUN-ANCY -> tkcnltkv sCprrkqnwhf ndligrCerstssf Cggkgntf stf keCqqtC 21
MET-CD -> HELAHNLGCnHDGD 240



MET-CD -> HELAHNLGCQHDGD 330



MET-CD -> HELAHNLGCQHDGD 330
                                                                           MET-CD -> HELAHNLGCQHDGD 209




                                                                                                          5-CYS-RGD -> CpyslCeedkdCgsiplCrCfpprgdlpgkrC 25




                                                                                                          5-CYS-RGD -> CpdslCekdedCgylplCqClpprgdlpgkrC 25




                                                                                                          5-CYS-RGD -> ClhslCntnedCgdpalCiCsphrgdfpgnwC 26




SCO-PONDIN -> CeekwphskpgalagCfinCneqnqdnstvkihtltlsngspCiiyggvCndgkC 79




SCO-PONDIN -> CnetwpnsepgavggCyvnCkqknentetvtihtltrsdgspCllaggtCqngvC 55
6-CYS-LONG -> ChlddehltalttCvghgmtealrtklqavttslsCentvCtlrklCeqeplstvsvfndeekhefrtlaagC 36




6-CYS-LONG -> ChlddtaltaltqCvgaqvseglraklhdvttrlsCentvCtlkklCeqeplstvsvftaeeklefrtlaagC 36
CY S-4 -> Cldiiev hgnlsCalegsgdlqnv dpmsCtleCsgngrpklpnglCsnndlnC 29




CY S-4 -> CleiieehgnisCalegsgdlqnv dpmsCtleCsgngrpklpnglCsnndlnC 29




CY S-4 -> Cmdmlv qcgeimCrlv gsgglrdy dpnf CrleCagsampsv pdgv Crgdv rnC 35




CY S-4 -> CmdlidqgghlkCgldgsgdiddy y pdtCslkCsgganpklpsgv Csgggv nC 29




CY S-4 -> CmdiidhagerkCglegsgdlddidptsCtlkCsgkerpklptgv Csggev v C 29




CY S-4 -> Cldiieny gnisCalegf gelv nv dpmlCtlv CsgngrpklpsgiCsnnelnC 29




CY S-4 -> CmdlideggeisCglsgsgniddy dpdsCnlkCsgganpklpsgv Csgggv nC 29




CY S-4 -> Cmdllsdcgy ieCllrgggaf mdy nprf CtldCsgnv wpkv pdgv Crgdv ehC 35




CY S-4 -> Cmdtlv dcgemkCrlegsgglqdy dpnsCrleCkgsarpsv pdgv Crgdv rnC 35




CY S-4 -> CidlidegghisCglagsggiddy dpy sCalrCsgggnpklpkgv Csgggv nC 29
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



                                                                           8-CYS
                      SMALL           SMALL                               SIMILAR
                     PEPTIDE         PEPTIDE                                 TO
                     CYSTEIN         CYSTEIN                              SCORPIO
                         E               E                       ANTIMIC      N
                     FRAMEW          FRAMEW                       ROBIAL TOXINS
                      ORK C-          ORK C-            4-CYS-1 PEPTIDE C-X(18)-C- YGGC C-                                                                      TFPI-COX       10KDAPE
                      X(3)-C-         X(4)-C- 5-CYS C- FRAMEW CONTAIN X(4)-C- X(3)-I-Y-G- PCGP                                                                  [QEN]-F-       P C-X-
                      X(5)-C-         X(5)-C-  X(6)-C-  ORK C- ING GGY X(11)-C-      G-C-G- ixostatin LPTSon                                                    [AS]-[ST]-     [NDV]-X-
                      X(3)-C-         X(4)-C-  X(24)-C-  X(8)-C- REPEATS X(8)-C-     X(11)-C domain P- coxy                                                     X-[KDE]-       [IV]-[DE]-
                      X(2)-C-         X(2)-C-  X(11)-C- X(18)-C- G-G-Y-G- X(11)-C-C- Kunitz C-G-P-X- [LVI]-P-                                                   [KDE]-C-       X(2)-G-X- WC coxy
                      X(10)-C.        X(9)-C.  X(3)-C.   X(6)-C.   G-Y.    X(4)-C.   domain. G-[QE]. [TS]-C.                                                    K.             [LI]-X-C.  motif
                                                                                                                                YGGC -> CkpfIYGGCGgnennfktkeeC 55



                                                                                                                                YGGC -> CksftYGGCGgngnnfktlkkC 55




                                                                                                                                                                    TFPI-COX -> NFpSlEECK 64




5-CY S -> CekppsnCf gdav tv y v y nrtggchpv glneeCsgy gy y mtpddChkkC 36




5-CYS -> CekpprhClgteftvytynrtlgctgvrlkeeCrkhgyytsqdeChqkC 36




5-CYS -> CekppsnClgvavtvyvynitegrypvglnqeCsgngyyttpddChrkC 36




                                                                           4-CYS-1 -> CrtpvpssmCaedaktrtiysfnnntnkCervqdsC 25




                                                                           4-CYS-1 -> CrtpvpssmCaedaktrtiysfnnntnkCervqdsC 25




                                                                           4-CYS-1 -> CrtpvpssmCvedaktrtiysfnnntnkCervqdsC 25
                                                                                                                                                                    TFPI-COX -> EFSTeDECK 63


                                                                                                                                                                    TFPI-COX -> EFSTeDECK 63




                                                                          4-CYS-1 -> CrfpvpvtsCaegaelrtvysfnnntnqCepvrgsC 25




                                                                                                                               YGGC -> CleyIYGGCGpdgggyrtmdqC 44




                                                                                                                                                                    TFPI-COX -> QFASlKKCK 78


5-CY S -> CekppsnClgnasy ay v y nrtkgcy sv glsegCgnngy y ttpqdChqy C 36




                                                                                                                                                                    TFPI-COX -> NFeSeEECK 139




                                                                                                                               YGGC -> CrsfIYqGCGgnennfptkrtC 256
SM-CYS -> CrrfCdtprdCtkiCnkChpgnpwtpkkC 35




SM-CYS -> CrqfCngpgnCgppCpnCkgnwwnpnkce 36




SM-CYS -> CnkkCsgrsdCdwpCekCqynayqgrkrC 37




SM-CYS -> CdkpCstndqCgwpCpwCkyhqywkkklC 37                                                                                                                                       WC
SM-CYS -> CekpCkepsdCkrpCirCnnhpwgdtlck 34




SM-CYS -> CkqlCdgdhqCggpCpkCrgtfwtpkeca 36




SM-CYS -> CsqvCrtpsdCgppCpnCiggiwtsyqck 37




                                             CYS6-SMALL-2 -> CyrkeCtkdedCktgsCsrCnnnvw gdntC 34




                                             CYS6-SMALL-2 -> CykieCtkdadCkrgsCsrCnsnvw gdntC 34




                                             CYS6-SMALL-2 -> CtmtdCksndqCqdppCsrCdsgaw gtgrC 38




                                             CYS6-SMALL-2 -> CysipCrkhdeCrvgsCsrCnnglwgdrtC 38




                                             CYS6-SMALL-2 -> CyritCtkdeeCkvgsCsyCnnglwgdntC 38




                                             CYS6-SMALL-2 -> CykkvCsnnsqCkvgsCsyCnnspw gdntC 38




                                             CYS6-SMALL-2 -> CykkaCkedneCkfgsCsrCnnglygdntC 38




                                             CYS6-SMALL-2 -> CtktlCtnndqCndppCtrCssnpwgsgtC 34




                                             CYS6-SMALL-2 -> CtktpCtndgeCkeppCskCkngpw gsntC 34




                                             CYS6-SMALL-2 -> CinkpCkhdggCkeppCsrCsnnpw gsgtC 34




                                                                                                  8-CYS -> CkwgnylvpdgeslnledpCqtwqCsvedrsfavlgCglignpynCeivrgtgpypnCCyrtnC 36




                                                                                                  8-CYS -> CrymnrtvqdgedmhledpCqtlkCeakkgsfailgCgimsskpgCklekgtgvfpqCCyksvC 37




                                                                                                  8-CYS -> CrymnrtvqdgedmhledpCqtlkCeakkgsfailgCgimaskpgCklekgtgvfpqCCyksvC 37




                                                                                                  8-CYS -> CkwgnylvpdgeslnledpCqtwqCsvedrsfavlgCglignpynCeivrgtgpypnCCyrtnC 36
                      WC




PCGP -> PCGPsGQ 104




PCGP -> PCGPdGQ 92




PCGP -> PCGnyGQ 88




PCGP -> PCGPqnQ 96




PCGP -> PCGPckE 70

PCGP -> PCGenGQ 89




PCGP -> PCGPkGE 92




PCGP -> PCGPnGQ 113




                      WC
                                                                                                        WC




                                                                                                        WC
5-CYS -> CrghrerCpdcteselqqrwsqlpelaaefhrCpdlsesdpvknClyvC 93                                           WC




                                                                                   PCGP -> PrGPnGQ 84




                                                                                                        WC




                                                                                                        WC



                                                                GGY -> GGYGGY 34




                                                                GGY -> GGYGGY 57

                                                                GGY -> GGYGGY 26
                               WC




                               WC
                               ClDiIEvhGnLsC 29
                   10KDAPEP -> WC
                               WC
                               WC
                               WC
                               WC
                               WC
                               WC
                               WC
                               WC
                               CmDlIDqgGhLkC 29
                   10KDAPEP -> WC
                               WC
                               WC
                               ClDiIEnyGnIsC 29
                   10KDAPEP -> WC
                               ClDiIEdhGnIsC 29
                   10KDAPEP -> WC
                               CmDlIDegGeIsC 29
                   10KDAPEP -> WC
                               WC
                               WC
                               CiDlIDegGhIsC 29
                   10KDAPEP -> WC
                               WC
                               CyNsVDpiGnLlC 36
                   10KDAPEP -> WC


                   10KDAPEP -> CyNsVDpiGnLlC 29

                   10KDAPEP -> CvNiIEeaGgLlC 30




LPTS -> VPSC 133



LPTS -> LPSC 148

LPTS -> VPSC 159

LPTS -> LPTC 170

LPTS -> VPTC 170

LPTS -> LPSC 161

LPTS -> LPSC 161

LPTS -> IPSC 127

LPTS -> LPSC 148
-----------------------------------------------------------------------------------------




                                                                                              Best
                                                                                            match to
                                                                                               NR                                           Length of
                      WP coxy                                                                protein                           Extent of      best            % Match
                       motif                           CPC coxy motif                       database     E value     Match      match        match % identity length


                                                                                                           1E-066 gi|22164184
                                                                                            putative secreted protein [Ixodes sca   121         121    92       100
                                                                                                           7E-067 gi|22164184
                                                                                            putative secreted protein [Ixodes sca   121         121    92       100
                                                                                                           5E-072     scapularis]
                                                                                            putative protein [Ixodesgi|22164156     121
                                                                                                                                     271        121
                                                                                                                                            5e-072     100      100
                                                                                                           1E-070 4 [Ixodes s
                                                                                            fed tick salivary proteingi|55736023    125         125    94       100
                                                                                                           1E-069 gi|22164188
                                                                                            putative secreted protein [Ixodes sca   120         120    100      100
                                                                                                           1E-073 gi|22164174
                                                                                            putative secreted protein [Ixodes sca   125         125    100      100
                                                                                                           1E-071 4 [Ixodes s
                                                                                            fed tick salivary proteingi|55736023    125         125    96       100
                                                                                                           2E-066 gi|22164184
                                                                                            putative secreted protein [Ixodes sca   121         121    92       100
                                                                                                           2E-067 gi|22164192
                                                                                            putative secreted salivary protein [I   121         126    98       96
                                                                                                           3E-072 gi|22164184
                                                                                            putative secreted protein [Ixodes sca   121         121    100      100
                                                                                                           2E-065 gi|15428308
                                                                                            14 kDa salivary gland protein [Ixodes   120         125    92       96
                                                                                                           5E-068 gi|22164184
                                                                                            putative secreted protein [Ixodes sca   121         121    95       100
                                                                                                           2E-071     scapularis]
                                                                                            putative protein [Ixodesgi|22164156     121
                                                                                                                                     268        121
                                                                                                                                            2e-071     98       100
                                                                                                           2E-071 gi|22164176
                                                                                            putative secreted protein [Ixodes sca   121         121    100      100
                                                                                                           2E-073 4 [Ixodes s
                                                                                            fed tick salivary proteingi|55736023    125         125    100      100
                                                                                                           1E-068 gi|22164184
                                                                                            putative secreted protein [Ixodes sca   121         121    95       100
                                                                                                           2E-071 gi|22164186
                                                                                            salivary secreted protein [Ixodes sca   121         121    100      100
                                                                                                           9E-064     scapularis]
                                                                                            putative protein [Ixodesgi|22164156     121
                                                                                                                                     243        121
                                                                                                                                            9e-064     90       100
                                                                                                           1E-070 gi|22164164
                                                                                            putative secreted protein [Ixodes sca   121         121    100      100
                                                                                                           2E-073 gi|15428308
                                                                                            14 kDa salivary gland protein [Ixodes   125         125    100      100
                                                                                                           4E-073 gi|22164192
                                                                                            putative secreted salivary protein [I   126         126    100      100
                                                                                                           7E-071     scapularis]
                                                                                            putative protein [Ixodesgi|22164154     122
                                                                                                                                     267        122
                                                                                                                                            7e-071     100      100
                                                                                                           5E-071 gi|22164180
                                                                                            putative secreted protein [Ixodes sca   122         122    100      100
                                                                                                           4E-071 gi|22164166
                                                                                            putative secreted protein [Ixodes sca   122         122    100      100
                                                                                                           2E-065 gi|22164182
                                                                                            putative secreted protein [Ixodes sca   121         122    92       99
                                                                                                           5E-071 gi|22164160
                                                                                            putative secreted protein [Ixodes sca   122         122    100      100
                                                                                                           3E-069     scapularis]
                                                                                            putative protein [Ixodesgi|22164154     121
                                                                                                                                     261        122
                                                                                                                                            3e-069     98       99
                                                                                                           6E-071 gi|22164162
                                                                                            putative secreted protein [Ixodes sca   122         122    100      100
                                                                                                           3E-062 gi|22164162
                                                                                            putative secreted protein [Ixodes sca   121         122    89       99
                                                                                                           5E-071 gi|22164172
                                                                                            putative salivary protein [Ixodes sca   122         122    100      100
                                                                                                           8E-071 gi|22164168
                                                                                            putative secreted protein [Ixodes sca   122         122    100      100
                                                                                                           9E-071 gi|22164170
                                                                                            putative secreted protein [Ixodes sca   122         122    100      100
                                                                                                           7E-068 gi|22164180
                                                                                            putative secreted protein [Ixodes sca   121         122    95       99
                                                                                                           1E-063 gi|22164160
                                                                                            putative secreted protein [Ixodes sca   121         122    89       99
                                                                                                           2E-071 gi|22164182
                                                                                            putative secreted protein [Ixodes sca   122         122    100      100
                                                                                                           5E-071 gi|22164178
                                                                                            putative secreted protein [Ixodes sca   122         122    100      100
                                                                                                           8E-041 gi|51011432
                                                                                            BTSP-11 [Ixodes pacificus]              94
                                                                                                                                    166         118
                                                                                                                                           8e-041      79       80
                                                                                                           1E-056 gi|22164184
                                                                                            putative secreted protein [Ixodes sca   106         121    91       88
                                                                                                           5E-049 gi|51011432
                                                                                            BTSP-11 [Ixodes pacificus]              194
                                                                                                                                    117         118
                                                                                                                                           5e-049      74       99
                                                                                                           4E-043 gi|51011432
                                                                                            BTSP-11 [Ixodes pacificus]              175
                                                                                                                                    153         118
                                                                                                                                           4e-043      56       130
                                                                                                           2E-060 gi|51011432
                                                                                            BTSP-11 [Ixodes pacificus]              232
                                                                                                                                    118         118
                                                                                                                                           2e-060      89       100
                                                                                                           4E-070 gi|22164194
                                                                                            putative secreted protein [Ixodes sca   120         120    100      100

                                                                                                          4E-057     scapularis]
                                                                                            putative protein [Ixodesgi|22164158      221     102
                                                                                                                                    102 4e-057         100      100
                                                                                                          6E-054     scapularis]
                                                                                            putative protein [Ixodesgi|22164152      211 6e-054
                                                                                                                                    96       96        100      100
                   3E-051 gi|22652868
     putative anticoagulant Salp9 [Ixodes 91     102   100   89
                   2E-045 gi|22652868
     putative anticoagulant Salp9 [Ixodes 90     102   90    88
                   2E-046 gi|22652868
     putative anticoagulant Salp9 [Ixodes 90     102   93    88
                   2E-045 gi|22652868
     putative anticoagulant Salp9 [Ixodes 90     102   88    88
                   3E-046 gi|22652868
     putative anticoagulant Salp9 [Ixodes 90     102   91    88
                   4E-045 gi|22652868
     putative anticoagulant Salp9 [Ixodes 90     102   88    88
                   2E-044 gi|22652868
     putative anticoagulant Salp9 [Ixodes 90     102   87    88
                   1E-043 gi|22652868
     putative anticoagulant Salp9 [Ixodes 90     102   86    88
                   6E-043 gi|22652868
     putative anticoagulant Salp9 [Ixodes 90     102   84    88
                     8.2    gi|47479435 49
     KRN1 protein [Homo sapiens] >gnl|BL_O       169   30    29
                   5E-060 gi|22164190
     putative secreted salivary protein [I 101   101   100   100



                    6E-032 gi|15428348 137 6e-03296
     Salp10 [Ixodes scapularis]            94          65    98
                    1E-052 gi|22164254
     putative secreted protein [Ixodes sca 96     96   100   100
                    8E-053 gi|22164252
     putative secreted protein [Ixodes sca 96     96   100   100
                    2E-053 gi|15428348 209 2e-05396
     Salp10 [Ixodes scapularis]            96          100   100
                    1E-049 gi|22164248
     putative secreted protein [Ixodes sca 91     91   100   100
                    5E-048 gi|22164250
     putative secreted protein [Ixodes sca 91     91   96    100
                    7E-050 gi|22164250
     putative secreted protein [Ixodes sca 91     91   100   100
                    1E-052 2 [Ixodes s
     fed tick salivary proteingi|55736019 96      96   100   100
                    1E-052 gi|22164258
     putative secreted protein [Ixodes sca 96     96   100   100
                    1E-052 gi|22164260
     putative secreted protein [Ixodes sca 96     96   100   100
                    8E-050 gi|22164246
     putative secreted protein [Ixodes sca 91     91   100   100
                    2E-047 gi|22164258
     putative secreted protein [Ixodes sca 96     96   90    100
                    2E-029 gi|22164286
     putative secreted protease inhibitor 82      82   70    100
                    7E-044 gi|22164286
     putative secreted protease inhibitor 82      82   100   100
                    8E-029 gi|22164218
     putative secreted protein [Ixodes sca 91     92   65    99
                    5E-027 gi|22164218
     putative secreted protein [Ixodes sca 85     92   65    92
                    2E-050 gi|22164218
     putative secreted protein [Ixodes sca 92     92   100   100
                    1E-044 gi|22164198
     putative secreted protein [Ixodes sca 81     81   100   100
                    1E-019 gi|22164204
     putative secreted protein [Ixodes sca 78     85   53    92
                    1E-018 gi|22164204
     putative secreted protein [Ixodes sca 78     85   51    92
                    1E-023 gi|22164214
     putative secreted protein [Ixodes sca 93     94   48    99
                    1E-053 gi|22164214
     putative secreted protein [Ixodes sca 94     94   100   100
                    4E-053 gi|22164216
     putative secreted protein [Ixodes sca 95     95   100   100
                    3E-052 gi|22164216
     putative secreted protein [Ixodes sca 95     95   97    100
                    2E-031 gi|22164204
     putative secreted protein [Ixodes sca 84     85   72    99
                    2E-025 gi|22164204
     putative secreted protein [Ixodes sca 82     85   63    96
                    6E-041 gi|22164212
     putative secreted protein [Ixodes sca 85     85   91    100
WP                  8E-046 gi|22164212
     putative secreted protein [Ixodes sca 85     85   100   100
                    2E-039 gi|22164212
     putative secreted protein [Ixodes sca 85     85   89    100
                    8E-027 gi|22164204
     putative secreted protein [Ixodes sca 86     85   63    101
                    6E-025 gi|51011560 114 6e-025 85
     KUN-6 [Ixodes pacificus]              84          64    99
                    5E-024 gi|22164204
     putative secreted protein [Ixodes sca 84     85   57    99
                    5E-046 gi|22164204
     putative secreted protein [Ixodes sca 85     85   100   100
                    2E-039 gi|22164204
     putative secreted protein [Ixodes sca 85     85   87    100
                    2E-043 gi|22164210
     putative secreted protein [Ixodes sca 84     84   94    100
                    4E-032 gi|22164208
     putative secreted protein [Ixodes sca 84     84   73    100
                    4E-045 gi|22164208
     putative secreted protein [Ixodes sca 84     84   100   100
                    3E-046 gi|22164210
     putative secreted protein [Ixodes sca 84     84   100   100
                    2E-049 gi|22164308
     putative 8.4 kDa secreted protein [Ix 91     91   93    100
                    3E-046 gi|22164308
     putative 8.4 kDa secreted protein [Ix 91     91   89    100
                    4E-053 gi|22164308
     putative 8.4 kDa secreted protein [Ix 91     91   100   100
                    3E-035 gi|22164256
     putative secreted protein [Ixodes sca 97     97   72    100
                    6E-030 gi|22164256
     putative secreted protein [Ixodes sca 97     97   64    100
                    1E-036 gi|22164256
     putative secreted protein [Ixodes sca 96     97   75    99
                    4E-050 gi|22164220
     putative secreted protein [Ixodes sca 94     94   97    100
                    8E-051 gi|22164220
     putative secreted protein [Ixodes sca 94     94   100   100
                    4E-037 gi|22164196 75
     putative salivary secreted protein [I        75   100   100
                    2E-051 gi|56159935
     putative secreted salivary gland pept 94     94   97    100
                    4E-051 gi|56159935
     putative secreted salivary gland pept 94     94   96    100
                    6E-053 gi|56159935
     putative secreted salivary gland pept 94     94   100   100
             2E-039 gi|22164206
putative secreted protein [Ixodes sca   79        81     92    98
             2E-043 gi|22164206
putative secreted protein [Ixodes sca   81        81     100   100
             6E-043 gi|22164200
putative secreted protein [Ixodes sca   81        81     100   100
             2E-043 gi|22164202
putative secreted protein [Ixodes sca   82        82     100   100
             2E-024 gi|22164258
putative secreted protein [Ixodes sca   97        96     57    101
             5E-032 gi|22164220
putative secreted protein [Ixodes sca   94        94     67    100
             1E-005 gi|22164286
putative secreted protease inhibitor    77        82     33    94
               2.1     gi|39997454
isoamylase family protein [Geobacte     47        630    36     7
             1E-052 gi|56159965
putative secreted salivary gland pept   95        95     100   100
             2E-054 gi|22164256
putative secreted protein [Ixodes sca   97        97     100   100

               1E-032 gi|51011414 140 1e-032142
KUN-5 [Ixodes pacificus]              134                47    94
               1E-010 gi|22164264
putative secreted protein [Ixodes sca 144    321         29    45
               1E-085 gi|51011542 316 1e-085 168
ixolaris-1 [Ixodes pacificus]         166                84    99
               4E-098 gi|15077002 358 4e-098 165
ixolaris [Ixodes scapularis]          165                100   100
               1E-103 gi|22164284
putative secreted protein [Ixodes sca 174    174         100   100
               1E-043 gi|51011606 177 1e-043 186
ixolaris-2 [Ixodes pacificus]         165                53    89
               3E-041 gi|51011606 169 3e-041 186
ixolaris-2 [Ixodes pacificus]         165                49    89
               9E-043 gi|51011606 174 9e-043 186
ixolaris-2 [Ixodes pacificus]         165                50    89
               1E-042 gi|51011606 174 1e-042 186
ixolaris-2 [Ixodes pacificus]         165                51    89
               9E-042 gi|51011606 171 9e-042 186
ixolaris-2 [Ixodes pacificus]         165                50    89
               5E-007 [Apis mellifera]      2760
similar to CG33103-PAgi|48120927 13856 5e-007            27     5

             1E-103 gi|22164264
putative secreted protein [Ixodes sca 254  321           66    79
             6E-022 gi|28572036 271
CG33103-PA, isoform A [Drosophila m       2894           28     9
             1E-127 gi|22164264
putative secreted protein [Ixodes sca 322  321           64    100
             1E-056 gi|22164262
putative secreted protein [Ixodes sca 314  319           35    98
             1E-140 gi|51011486 499 e-140 330
KUN-4 [Ixodes pacificus]              330                68    100
               0.0     gi|22164266
putative secreted protein [Ixodes sca 330  330           100   100
               0.0     gi|22164262
putative secreted protein [Ixodes sca 319  319           100   100
               0.0     gi|22164264
putative secreted protein [Ixodes sca 321  321           100   100

             2E-005 gi|46275812 36
keratin complex 1, acidic, gene 10                 570   61     6
             5E-032 gi|22164242
putative secreted protein [Ixodes sca 67            67   92    100
             3E-031 gi|22164228
putative secreted protein [Ixodes sca 64            65   95    98
             2E-031 gi|22164238
putative secreted protein [Ixodes sca 65            65   95    100
             7E-018 gi|22164238
putative secreted protein [Ixodes sca 66            65   62    102
             1E-032 gi|22164234
putative secreted protein [Ixodes sca 65            65   95    100
             5E-027 gi|22164224
putative secreted protein [Ixodes sca 63            65   84    97
             2E-029 gi|22164228
putative secreted protein [Ixodes sca 65            65   89    100
             2E-033 gi|22164242
putative secreted protein [Ixodes sca 67            67   97    100
             5E-029 gi|22164228
putative secreted protein [Ixodes sca 65            65   90    100
              0.008      melanogaster] 61
pericardine [Drosophilagi|6468017                 1729
                                              41 0.008   37     4
             2E-025 gi|51011544 116
CLSP-9 [Ixodes pacificus]               61   2e-02565    83    94
             1E-026 gi|51011464 120
CLSP-2 [Ixodes pacificus]               65   1e-02665    83    100
             1E-025 gi|22164238
putative secreted protein [Ixodes sca 65            65   81    100
              0.004 gi|6319085
bindin precursor [Echinometra mathaei]  48         102   45    47
              hypothetical protein XP_
PREDICTED: 0.051 gi|57108703 54                    648   37     8
             3E-024 gi|51011464 112
CLSP-2 [Ixodes pacificus]               62   3e-02465    82    95
             2E-019 gi|51011452 97
CLSP-1 [Ixodes pacificus]               86   2e-019 65   54    132
             2E-029 gi|22164238
putative secreted protein [Ixodes sca 64            65   92    98
             1E-026 gi|22164224
putative secreted protein [Ixodes sca 64            65   84    98
             3E-029 gi|22164228
putative secreted protein [Ixodes sca 65            65   90    100
             2E-004 gi|47224990
unnamed protein product [Tetraodon n70             444   41    16
             3E-006 gi|51011514 102
CLSP-11 [Ixodes pacificus]              52   3e-00679    38    129
             4E-018 gi|51011452 92
CLSP-1 [Ixodes pacificus]               86   4e-018 65   56    132
             3E-030 gi|51011460 132
CLSP-8 [Ixodes pacificus]               72   3e-03075    76    96
               1.3      gi|34913144 65
putative receptor-like protein kina               1059   32     6
             6E-026 gi|51011514 117
CLSP-11 [Ixodes pacificus]              65    6e-02679   83    82
              0.065 gi|22164226
putative secreted protein [Ixodes sca 70            65   37    108
              0.006 gi|283868           43
collagen alpha 1(XI) chain - chicken (frag         888   51     5
             1E-029 gi|22164238
putative secreted protein [Ixodes sca 65            65   89    100
                     1.3     gi|57094784
     PREDICTED: similar to dJ34F7.1.1 (t 40        4146   40     1
                   6E-029 gi|22164238
     putative secreted protein [Ixodes sca 65       65    87    100
                   6E-027 gi|51011464 121 6e-02765
     CLSP-2 [Ixodes pacificus]             65             83    100
                   4E-022 gi|51011404 104 4e-022 78
     NPL-2 [Ixodes pacificus]              77             72    99
                   9E-009 gi|51011544 61 9e-009 65
     CLSP-9 [Ixodes pacificus]             61             54    94
                   3E-028 gi|22164238
     putative secreted protein [Ixodes sca 65       65    87    100
                   8E-028 gi|22164228
     putative secreted protein [Ixodes sca 63       65    90    97
                   3E-034 gi|22164244
     putative secreted protein [Ixodes sca 67       67    100   100
                   2E-034 gi|22164242
     putative secreted protein [Ixodes sca 67       67    100   100
                   3E-034     scapularis]
     putative protein [Ixodesgi|22164240 65         65
                                            145 3e-034    100   100
                   1E-033 gi|22164238
     putative secreted protein [Ixodes sca 65       65    100   100
                   3E-034 gi|22164236
     putative secreted protein [Ixodes sca 65       65    100   100
                   3E-034 gi|22164234
     putative secreted protein [Ixodes sca 65       65    100   100
                   2E-034 gi|22164232
     putative secreted protein [Ixodes sca 65       65    100   100
                   2E-034 gi|22164230
     putative secreted protein [Ixodes sca 65       65    100   100
                   4E-033 gi|22164228
     putative secreted protein [Ixodes sca 65       65    100   100
                   4E-034 gi|22164226
     putative secreted protein [Ixodes sca 65       65    100   100
                   2E-034 gi|22164224
     putative secreted protein [Ixodes sca 65       65    100   100
                   4E-026 gi|22164222
     putative secreted protein [Ixodes sca 54       54    100   100

                   kDa secreted protein
     putative 18.7 2E-018 gi|22164316[I 175        186    34    94
                   kDa secreted protein
     putative 18.7 8E-052 gi|22164316[I 170        186    60    91
                   kDa secreted protein
     putative 18.7 1E-051 gi|22164316[I 169        186    56    91
                   kDa secreted protein
     putative 18.7 1E-043 gi|22164316[I 169        186    52    91
                    19 kDa gi|51011470
     18_2 putative6E-020 secreted protein189       190    33    99
                   kDa secreted protein
     putative 18.7 1E-113 gi|22164316[I 186        186    100   100

                   1E-022 gi|51011562
     putative secreted peptide of 6.3 kDa 64       79     71    81
                   1E-014 gi|51011556
     putative secreted peptide of 4.99 kDa 65      66     56    98
                    0.28    gi|49525702
     unnamed protein product [Candida gla41        627    41     7
                    0.003 gi|51011556
     putative secreted peptide of 4.99 kDa 32      66     50    48
                   2E-008 gi|51011556
     putative secreted peptide of 4.99 kDa 65      66     44    98
                   7E-009 gi|51011556
     putative secreted peptide of 4.99 kDa 64      66     46    97
                   5E-011 gi|51011556
     putative secreted peptide of 4.99 kDa 67      66     50    102
                   3E-020 gi|22164302
     putative 5.3 kDa secreted protein [Ix 69      69     66    100
                   2E-019 gi|22164302
     putative 5.3 kDa secreted protein [Ix 69      69     66    100
                   2E-018 gi|51011582
     putative secreted peptide of 4.3 kDa 70       72     60    97
                   1E-037 gi|22164302
     putative 5.3 kDa secreted protein [Ix 69      69     100   100
                   7E-023 gi|22164302
     putative 5.3 kDa secreted protein [Ix 69      69     71    100
                   1E-020 gi|22164302
     putative 5.3 kDa secreted protein [Ix 69      69     65    100
                   3E-020 gi|22164302
     putative 5.3 kDa secreted protein [Ix 69      69     65    100
                   9E-017 gi|51011582
     putative secreted peptide of 4.3 kDa 66       72     54    92
                   5E-019 gi|51011582
     putative secreted peptide of 4.3 kDa 66       72     59    92
                   4E-017 gi|51011582
     putative secreted peptide of 4.3 kDa 66       72     53    92

                   3E-028 gi|51011434
     putative secreted salivary peptide of   79    79     74    100
                   2E-071 gi|56159941
     putative secreted salivary gland pept   120   120    98    100
                   1E-034 gi|51011434
     putative secreted salivary peptide of   79    79     87    100
WP                 3E-042 gi|22164310
     putative 9.4 kDa secreted protein [Ix   101   101    72    100
WP                 2E-050 gi|22164310
     putative 9.4 kDa secreted protein [Ix   101   101    86    100
                   6E-038 gi|22164306
     putative 7 kDa secreted protein [Ixod   79    79     94    100
WP                 2E-042 gi|51011396
     putative secreted salivary peptide of   101   101    76    100
                   4E-032 gi|51011434
     putative secreted salivary peptide of   79    79     79    100
                   7E-022 gi|56159941
     putative secreted salivary gland pept   95    120    46    79
                   7E-022 gi|56159941
     putative secreted salivary gland pept   95    120    46    79
                   1E-072 gi|56159941
     putative secreted salivary gland pept   120   120    100   100
WP                 3E-059 gi|22164310
     putative 9.4 kDa secreted protein [Ix   101   101    100   100
                   4E-040 gi|22164306
     putative 7 kDa secreted protein [Ixod   79    79     100   100

                    0.0     gi|22164296
     truncated secreted metalloprotease [I 403     403    100   100
                    0.0     gi|31322780
     salivary gland metalloprotease [Ixode 488     488    100   100
                    0.0     gi|31322780
     salivary gland metalloprotease [Ixode 488     488    100   100
                     0.0    gi|22164294
      truncated secreted metalloprotease [I 367       367    100   100

                    2E-008 gi|51011476
      putative salivary secreted peptide [I   51       60    58    85
                    5E-008 gi|51011476
      putative salivary secreted peptide [I   51       60    56    85
                    1E-008 gi|51011476
      putative salivary secreted peptide [I   60       60    56    100
                    2E-005 gi|58569882
      GekBS205P [Gekko japonicus]                      256
                                              76 50 2e-005   34    30


CPC             7E-004 gi|58569882
      GekBS205P [Gekko japonicus]                      256
                                              77 44 7e-004   32    30



                     0.55     gi|6680259
      homeo box D12 [Mus musculus] >gnl|BL  67     279       41    24
                    3E-038 gi|15428296
      16 kDa salivary gland protein A [Ixod 133    144       58    92
                    1E-007 gi|15428296
      16 kDa salivary gland protein A [Ixod 136    144       30    94
                    7E-047 gi|22164274
      putative secreted protein [Ixodes sca 121    121       73    100
                    2E-041 gi|15428296
      16 kDa salivary gland protein A [Ixod 142    144       59    99
                      3.6     gi|51095044 37
      similar to 4930579E17Rik protein [Hom        617       35     6
                    2E-040 gi|15428296
      16 kDa salivary gland protein A [Ixod 136    144       60    94
                    7E-020 gi|15428296
      16 kDa salivary gland protein A [Ixod 82     144       56    57
                    2E-036 gi|15428294
      15 kDa salivary gland protein [Ixodes 131    135       54    97
                    7E-036 gi|15428290             114
      thrombospondin [Ixodes scapularis] 114150 7e-036       59    100
                    3E-016 gi|15428290             114
      thrombospondin [Ixodes scapularis] 114 85 3e-016       39    100
                    2E-037 gi|51011596 155 2e-037114
      THR2 [Ixodes pacificus]               114              58    100
                    3E-051 gi|22164272
      putative secreted protein [Ixodes sca 114    114       76    100
                    3E-011 gi|15428294
      15 kDa salivary gland protein [Ixodes 127    135       34    94
                    8E-034 gi|51011596 143 8e-034114
      THR2 [Ixodes pacificus]               114              55    100
                     0.010 gi|15428296
      16 kDa salivary gland protein A [Ixod 116    144       28    81
                    5E-055 gi|22164272
      putative secreted protein [Ixodes sca 114    114       85    100
                    8E-005 gi|22164274
      putative secreted protein [Ixodes sca 83     121       31    69
                     0.73     gi|49645652
      unnamed protein product [Yarrowia li 88     1012       29     9
                    5E-005 gi|15428296
      16 kDa salivary gland protein A [Ixod 59     144       45    41
                    8E-042 gi|15428296
      16 kDa salivary gland protein A [Ixod 137    144       59    95
      4930404J24Rik7.9         [Mus musculus]
                       proteingi|15030168 80       122       27    66
                    3E-040 gi|15428296
      16 kDa salivary gland protein A [Ixod 132    144       60    92
                    1E-026 gi|56159939
      putative secreted salivary gland pept 115    112       53    103
                    7E-027 gi|56159939
      putative secreted salivary gland pept 115    112       53    103
                    3E-025 gi|15428294
      15 kDa salivary gland protein [Ixodes 133    135       46    99
                      2.0     gi|24635995 88
      Hypothetical protein Y39A3B.3 [Caenor        215       27    41
                     0.076 gi|56159939
      putative secreted salivary gland pept 72     112       26    64
                    8E-021 gi|56159939
      putative secreted salivary gland pept 107    112       47    96
                    5E-004 gi|22164274
      putative secreted protein [Ixodes sca 82     121       31    68
                    3E-062 gi|56159939
      putative secreted salivary gland pept 112    112       100   100
                    3E-064 gi|56159923
      putative secreted salivary gland pept 117    117       100   100
                    7E-075 gi|56159921
      putative secreted salivary gland pept 127    127       100   100
                    1E-067 gi|22164274
      putative secreted protein [Ixodes sca 121    121       100   100
                    1E-064 gi|22164272
      putative secreted protein [Ixodes sca 114    114       100   100
                    6E-083 gi|15428296
      16 kDa salivary gland protein A [Ixod 144    144       100   100
                    2E-075 gi|15428294
      15 kDa salivary gland protein [Ixodes 135    135       100   100
                    4E-064 gi|15428290             114
      thrombospondin [Ixodes scapularis] 114244 4e-064       100   100

                     kDa secreted protein
      putative 22.5 7E-067 gi|22164318[I 181       210       68    86
                      histamine-binding saliva199
      male-specific2E-004 gi|3452093               200       24    100
                     2E-097 gi|15428306
      26 kDa salivary gland protein B [Ixod 220    218       77    101
                     8E-012 gi|45360102
      lipocalin-like protein [Boophilus mic 160    201       28    80
                     3E-011 gi|45360102
      lipocalin-like protein [Boophilus mic 155    201       27    77
                     2E-093      scapularis]   343 222
      putative protein [Ixodesgi|22164276 223 2e-093         75    100
      dehydrogenase1.0          vulnificus YJ
                        [Vibrio gi|37676871 90     246       31    37
                     5E-088 gi|15428310
      25 kDa salivary gland protein A [Ixod 217    222       71    98
                     1E-102 gi|15428292
      histamine binding protein [Ixodes sca 222    221       77    100
                     1E-101 gi|15428292
      histamine binding protein [Ixodes sca 222    221       78    100
                     1E-101 gi|15428292
      histamine binding protein [Ixodes sca 221    221       80    100
                      0.004 gi|51011422
      truncated histamine binding protein [ 250    266       22    94
               kDa secreted protein
putative 22.7 1E-098 gi|22164320[I 223        223   79    100
               4E-008 gi|15428306
26 kDa salivary gland protein B [Ixod 245     218   24    112
               1E-012 gi|15428306
26 kDa salivary gland protein B [Ixod 204     218   26    94
               1E-010 gi|45360102
lipocalin-like protein [Boophilus mic 155     201   26    77
               kDa secreted protein
putative 22.5 8E-086 gi|22164318[I 208        210   71    99
                0.089 gi|51011416
putative secreted histamine binding p 143     194   23    74
               1E-103 gi|15428306
26 kDa salivary gland protein B [Ixod 220     218   81    101
               2E-011 gi|15428306
26 kDa salivary gland protein B [Ixod 202     218   26    93
               4E-061 gi|51011498
truncated histamine binding protein [ 157     160   70    98
               3E-017 gi|15428306
26 kDa salivary gland protein B [Ixod 200     218   29    92
               kDa secreted protein
putative 22.5 5E-084 gi|22164318[I 207        210   71    99
                19 kDa gi|51011570
18_3 putative1E-076 secreted protein183       190   69    96
               3E-016 gi|15428306
26 kDa salivary gland protein B [Ixod 199     218   29    91
               kDa secreted protein
putative 22.7 1E-081 gi|22164320[I 231        223   69    104
               kDa secreted protein
putative 22.7 5E-078 gi|22164320[I 232        223   67    104
               1E-129     scapularis]    461
putative protein [Ixodesgi|22164276 222 e-129 222   97    100
                19 kDa gi|51011570
18_3 putative1E-020 secreted protein183       190   33    96
               1E-107 gi|15428292
histamine binding protein [Ixodes sca 222     221   80    100
               4E-036 gi|22164278
putative secreted protein [Ixodes sca 174     220   43    79
               8E-041 gi|22164278
putative secreted protein [Ixodes sca 219     220   42    100
               2E-090     scapularis]    333
putative protein [Ixodesgi|22164276 223 2e-090222   73    100
               kDa secreted protein
putative 22.7 1E-103 gi|22164320[I 222        223   83    100
                histamine-binding saliva193
male-specific3E-004 gi|3452093                200   24    97
               4E-073 gi|51011498
truncated histamine binding protein [ 157     160   83    98
               7E-012 gi|51011416
putative secreted histamine binding p 213     194   29    110
               7E-007 gi|45360102
lipocalin-like protein [Boophilus mic 177     201   23    88
                 3.3     gi|34860609
similar to immunoglobulin superfami 75       1387   26     5
               5E-008 gi|51011416
putative secreted histamine binding p 144     194   29    74
               6E-058 gi|56159943
putative secreted salivary gland pept 172     236   69    73
               1E-136 gi|56159943
putative secreted salivary gland pept 236     236   100   100
               kDa secreted protein
putative 22.7 1E-131 gi|22164320[I 223        223   100   100
               kDa secreted protein
putative 22.5 1E-124 gi|22164318[I 210        210   100   100
               1E-130 gi|22164278
putative secreted protein [Ixodes sca 220     220   100   100
               1E-132     scapularis]    473
putative protein [Ixodesgi|22164276 222 e-132 222   100   100
                 0.0     gi|22164270
putative secreted histamine binding p 311     311   100   100
               1E-178 gi|22164268
putative secreted histamine binding p 306     306   100   100
               1E-132 gi|15428310
25 kDa salivary gland protein A [Ixod 222     222   100   100
               1E-129 gi|15428306
26 kDa salivary gland protein B [Ixod 218     218   100   100
               1E-132 gi|15428302
25 kDa salivary gland protein B [Ixod 222     222   100   100
               4E-086 gi|15428298
17 kDa salivary gland protein [Ixodes 150     150   100   100
               1E-131 gi|15428292
histamine binding protein [Ixodes sca 221     221   100   100

             1E-042 gi|56159955
putative secreted salivary gland pept 77   77       100   100
             9E-093 gi|56159959
putative secreted salivary gland pept 161 161       100   100
             1E-017 gi|39586024 72
Hypothetical protein CBG15126 [Caeno      128       65    56
             2E-035 gi|51011444 149 2e-035 73
NPL-1 [Ixodes pacificus]              72            93    99



             3E-038 gi|56159961
putative secreted salivary gland pept 74     74     100   100

              7E-010 gi|51011474
putative salivary secreted peptide wi 40     45     82    89
              4E-009 gi|51011474
putative salivary secreted peptide wi 40     45     80    89



             2E-063 gi|51011420
truncated glutathione peroxidase [Ixo 117  117      96    100
             1E-129 [Ixodes scapul
glutathione peroxidase gi|15428288 221     221      100   100
             1E-104 gi|47227198 248
unnamed protein product [Tetraodon n       261      74    95
             5E-084 gi|49256209            251
MGC83969 protein [Xenopus laevis] 245 312 5e-084    64    98
             1E-082 gi|55725787 208        256
hypothetical protein [Pongo pygmaeus] 308 1e-082    71    81

            2E-033 gi|24666045 143
CG7484-PB [Drosophila melanogaster]          178    46    80
            7E-014 gi|27805721 92
Selenoprotein M precursor (SelM              145    43    63
                    W2a [Danio rerio] >gnl|
      selenoprotein4E-015 gi|29165352 100           95    51    105

                   3E-094 gi|15428300
      20 kDa salivary gland protein [Ixodes 183 183       91    100
                   1E-081 gi|15428300
      20 kDa salivary gland protein [Ixodes 184 183       82    101
                   4E-081 gi|15428300
      20 kDa salivary gland protein [Ixodes 183 183       79    100
                   2E-092 gi|8896135
      anticomplement protein [Ixodes scapula183 184       90    99
                   1E-105 gi|8896135
      anticomplement protein [Ixodes scapula184 184       100   100
                    scapularis]             81
      Salp9 [Ixodes5E-042 gi|15428346 171 5e-042 81       100   100
                   1E-103 gi|15428300
      20 kDa salivary gland protein [Ixodes 183 183       100   100

                     0.95    gi|56159937
      putative secreted salivary gland pept 123     119   28    103

                      1.7    gi|16077235
      hypothetical protein BSU01670 [Baci     78    441   29    18
                    3E-017 gi|56159949
      putative secreted salivary gland pept   121   122   40    99
CPC                 kDa secreted protein
      putative 10.2 5E-031 gi|22164314[I      115   115   53    100
CPC                 kDa secreted protein
      putative 10.2 3E-033 gi|22164314[I      115   115   55    100
                    2E-018 gi|56159949
      putative secreted salivary gland pept   120   122   44    98
                    3E-024 gi|56159937
      putative secreted salivary gland pept   113   119   50    95
                    5E-027 gi|56159937
      putative secreted salivary gland pept   119   119   52    100
                    2E-024 gi|56159949
      putative secreted salivary gland pept   118   122   46    97
                    2E-045 gi|56159949
      putative secreted salivary gland pept   115   122   71    94
                    3E-021 gi|56159949
      putative secreted salivary gland pept   121   122   42    99
                    kDa secreted protein
      putative 10.2 2E-029 gi|22164314[I      114   115   53    99
                    kDa secreted protein
      putative 10.2 4E-047 gi|22164314[I      115   115   74    100
CPC                 kDa secreted protein
      putative 10.2 2E-032 gi|22164314[I      115   115   57    100
                    1E-022 gi|56159937
      putative secreted salivary gland pept   111   119   45    93
CPC                 kDa secreted protein
      putative 10.2 4E-029 gi|22164314[I      115   115   51    100
CPC                 kDa secreted protein
      putative 10.2 2E-027 gi|22164314[I      128   115   48    111
CPC                 kDa secreted protein
      putative 10.2 3E-048 gi|22164314[I      115   115   77    100
                    kDa secreted protein
      putative 10.2 3E-026 gi|22164314[I      115   115   49    100
                    kDa secreted protein
      putative 10.2 1E-029 gi|22164314[I      114   115   53    99
                    kDa secreted protein
      putative 10.2 3E-064 gi|22164314[I      115   115   100   100
                    2E-065 gi|56159937
      putative secreted salivary gland pept   119   119   100   100
                    1E-069 gi|56159949
      putative secreted salivary gland pept   122   122   100   100
                    8E-013 gi|56159949
      putative secreted salivary gland pept   69    122   53    57
                    kDa secreted protein
      putative 10.2 7E-007 gi|22164314[I      119   115   32    103
                    1E-020 gi|56159949
      putative secreted salivary gland pept   48    122   97    39
                      1.1    gi|56159949
      putative secreted salivary gland pept   95    122   27    78
                    8E-008 gi|56159949
      putative secreted salivary gland pept   77    122   41    63
                    2E-030 gi|56159919
      putative secreted salivary gland pept   98    104   65    94
                    4E-023 gi|56159949
      putative secreted salivary gland pept   106   122   48    87
                    3E-025 gi|56159949
      putative secreted salivary gland pept   107   122   49    88
                    8E-037 gi|22164304
      putative 6.4 kDa secreted protein [Ix   75    75    100   100
                    1E-055 gi|56159919
      putative secreted salivary gland pept   104   104   100   100

                    1E-022 gi|51011590
      putative peptide 14.4 kDa [Ixodes pac 157     154   43    102
                    8E-029 gi|51011394
      putative peptide 11.9 kDa [Ixodes pac 152     123   44    124
                    2E-039 gi|51011394
      putative peptide 11.9 kDa [Ixodes pac 153     123   54    124
                    2E-028 gi|51011590
      putative peptide 14.4 kDa [Ixodes pac 164     154   40    106
                    2E-028 gi|51011590
      putative peptide 14.4 kDa [Ixodes pac 175     154   41    114
                    2E-099 gi|56159933
      putative secreted salivary gland pept 174     174   100   100
                    1E-030 gi|12002008
      salivary gland 16 kD protein [Ixodes 165      152   44    109
                    1E-036 gi|51011590
      putative peptide 14.4 kDa [Ixodes pac 164     154   46    106
                    4E-077 gi|56159925
      putative secreted salivary gland pept 131     131   100   100
                    2E-085 gi|12002008
      salivary gland 16 kD protein [Ixodes 152      152   100   100
                    2E-034 gi|12002008
      salivary gland 16 kD protein [Ixodes 167      152   46    110



                    1E-117 scapularis]       424  213
      putative serpin [Ixodes gi|22164288 213 e-117       100   100
                      0.0     gi|56159953
      putative secreted salivary gland pept 393   393     100   100

                   5E-052 gi|22164282
      putative secreted cystatin [Ixodes sc 133     133   75    100
                   3E-072 gi|22164282
      putative secreted cystatin [Ixodes sc 133       133        100   100

                     0.004 gi|56462340                 86
      protease inhibitor 6 [Lonomia obliqua] 93 42 0.004         32    108
                     0.002 gi|19572353
      cysteine-rich venom protein 6 [Pimpl 94          77        28    122

                   8E-008 gi|45478208 107 58 8e-008
      LRRGT00184 [Rattus norvegicus]                 596         33    18
                   4E-006 gi|54657421
      hypothetical protein Chro.40415 [Cryp156      1042         28    15
                    0.017     of the Srp1p/ 70
      Cell wall mannoprotein gi|6324583              487         42    14
                    0.065      c [Caenorhabd
      Long protein 1, isoformgi|21328348 58          287         39    20
                   4E-009                   110
      Is3 [Ixodes scapularis] gi|29649819 62 4e-009 108          35    102
                   6E-010 gi|41352541
      mucin/peritrophin-like protein precur 105      194         34    54
                   2E-010 gi|41352541
      mucin/peritrophin-like protein precur 105      194         34    54

CPC                6E-064 gi|56159957
      putative secreted salivary gland pept 116       116        100   100
CPC                2E-020 gi|56159957
      putative secreted salivary gland pept 127       116        44    109
CPC                5E-004 gi|50749272
      PREDICTED: similar to Dkk-1 [Gallus 81          341        32    24



                   1E-038 gi|56159931
      putative secreted salivary gland pept 135       135        61    100
                   2E-040 gi|56159931
      putative secreted salivary gland pept 135       135        63    100
                   8E-074 gi|56159931
      putative secreted salivary gland pept 135       135        100   100

                   1E-134 gi|15428304
      26 kDa salivary gland protein A [Ixod 233       233        100   100
                   1E-108 gi|56159927
      putative secreted salivary gland pept 190       190        100   100

                    1E-109 gi|51011406
      putative salivary secreted peptide [I   219     225        88    97
                    1E-107 gi|51011406
      putative salivary secreted peptide [I   219     225        86    97



                    2E-032 gi|51011472
      putative salivary secreted peptide [I   87      88         77    99

                     sensorgi|58337789 114
      two-component5.4      histidine kina            525        21    22
                    1.3     gi|51513445
      Npc2-prov protein [Xenopus tropicalis 46        151        30    30

                       0.0     gi|22164290
      putative secreted carboxypeptidase [I 350       350        100   100
                        proteingi|55736035 394
      fed tick salivary0.0      10 [Ixodes            394        100   100
                     1E-036 gi|48098816 244
      similar to serine proteinase [Apis              255        36    96
                     1E-005 gi|39591154 103
      Hypothetical protein CBG20611 [Caeno            739        30    14
                     1E-028 enzyme-like 162
      angiotensin-converting gi|1468981 pro           660        41    25
                     2E-024 gi|30923682 91
      CG40127-PA.3 [Drosophila melanogaster           95         56    96
                     4E-013 gi|51011418
      putative salivary secreted peptide [I 94        196        38    48

                 [Drosophila pseudoobscura]
      GA22109-PA1E-014 gi|54637112 208                  1e-014
                                                    82 250       25    83




                     8.2     gi|33603656
      putative malate/L-lactate dehydroge     27      356        51    8

                  0.25      gi|46324461
      COG4232: Thiol:disulfide intercha       56      352        30    16




                    2E-028 gi|22164300
      putative 4.3 kDa secreted protein [Ix 61        61         100   100
                    1E-025 gi|51011426
      putative salivary secreted peptide [I 54        54         98    100
                      2.4     gi|28797323
      putative helicase [Streptomyces viola 62        866        30     7
                    1E-008 gi|51011562
      putative secreted peptide of 6.3 kDa 65         79         46    82
                      2.1     gi|31430729
      putative membrane protein [Oryza sati 60        464        38    13
                     0.050 gi|31430385
      hypothetical protein [Oryza sativa (j 64        728        37     9

                     6.6     gi|34898592
      hypothetical protein [Oryza sativa      27      106        48    25
                   1.3      protein, see:
conserved hypotheticalgi|1673769 M57             672        35     8
Notch homolog1.6           - sea squirt   38
                   protein gi|7522619 (Haloc    2352        39     2
                   2.8     gi|56677223 62
ABC transporter, transmembrane ATP-bi           1032        33     6
                   2.6     gi|51011484
putative peptide 11.9 kDa [Ixodes pac 113        119        23    95
                   4.3     gi|33596276
hypothetical protein BPP1641 [Borde 70           461        30    15
                3E-027 gi|45386069
secreted protein PK-4 precursor [Orni 94         110        59    85
                3E-055 gi|56159963
putative secreted salivary gland pept 114        114        100   100
                   2.1     gi|23612987
hypothetical protein [Plasmodium fa 29          2568        37     1
                1E-076 gi|56159945
putative secreted salivary gland pept 138        138        100   100
                  0.43     gi|21323034 88
Predicted membrane protein [Coryneba             495        29    18
                1E-018 gi|55237569 123
ENSANGP00000010503 [Anopheles gambiae 143                   39    86
                  0.15     gi|15606451
septum site-determining protein Min 65           278        27    23
                 0.001 gi|47221376
unnamed protein product [Tetraodon n55           675        40     8
                2E-004 gi|24583498 33
CG7296-PA [Drosophila melanogaster]              161        63    20
                2E-096 gi|56159951
putative secreted salivary gland pept 171        171        100   100
                   1.1     gi|17938449 57
transcriptional regulator, GntR fam              482        33    12
                3E-004 gi|23490698
hypothetical protein [Plasmodium yoel136         396        31    34
                 0.002 gi|12655472
keratin associated protein 9.5 [Homo 85          111        34    77
                 [Drosophila pseudoobscura]
GA14264-PA5E-035 gi|54644951 144                   5e-035
                                              148146        47    99
                  0.76     gi|1519707
ORFveg106; random cDNA sequence139                 0.76
                                               36715        23    19
                   3.1     gi|56118314 39
NACHT, leucine rich repeat and P                1098        33     4
                   2.9     gi|52006613
COG0557: Exoribonuclease R [Thiob 55             758        32     7
                4E-066 gi|58422507 253 4e-066 286
Ixoderin B [Ixodes ricinus]               233               56    81
                5E-069 gi|56159929
putative secreted salivary gland pept 135        135        100   100
                   0.0     gi|51243761 884 0.0
calreticulin [Ixodes scapularis]          413    413        100   100
                7E-013 gi|34869750 81
similar to RPGR-interacting protein             1311        48     6
                 0.018 gi|53767905 77
hypothetical protein Krad07003954                771        41    10
            First                                                        Best
   First  residue                                                      match to                          All
 residue     of                                Comment                    GO                          descripto
of match sequence Species      Key words          s           Class    database         E value          rs         Parent


   1        1               PUTATIVE SECRETEDtail
                 Ixodes scapularis        basic IXODES SCAPULARIS SALIVARY 0.007 primary transcript processing - RNA bindingBTSP-1 1 B
                                                        s/bt                              35S        RNA binding||nucleic acid binding||binding
                                                                                                                 binding
                                                                    snRNA processing4- GLAND BTSP-2 PACIFICUS BTSP 2 BTSP-6 6 - nucleolus
   1        1               PUTATIVE SECRETEDtail
                 Ixodes scapularis        basic IXODES SCAPULARIS SALIVARY 0.009
                                                        s/bt                            4 GLAND BTSP-1 PACIFICUS BTSP 1 BTSP-6 6 BTSP-2 2 B
                                                                    physiological process                        transporter activity
                                                                                                     potassium channel activity||cation channel activity
   1        1    Ixodes scapularis
                            PUTATIVE IXODES SCAPULARIS SECRETED SALIVARY 0.005
                                          basic tail protein
                                                        s/bt                            4 GLAND BTSP-6 PACIFICUS BTSP 6 BTSP-1 1 BTSP-2 2 B
                                                                    negative regulation of body size             catalytic activity
                                                                                                     ATP-dependent DNA helicase activity||DNA-depe
   1        1               SALIVARY 4 IXODES SCAPULARIS PUTATIVE SECRETED- BTSP-1 PACIFICUS BTSP 1 BTSP-6 6 GLAND BTSP-2 2 B
                 Ixodes scapularis        basic tail    s/bt                           0.006         RNA binding||nucleic acid binding||binding
                                                                                                                 binding
                                                                    snRNA processing 35S primary transcript processing - RNA binding - nucleolus
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARIS SALIVARY 0.058potassium channeltransporter activity ion transport 2 B
                                                        s/bt                            GLAND 4 BTSP-1 PACIFICUS BTSP 1 BTSP-6 6 BTSP-2
                                                                    integral to membrane -                        activity - potassium
                                                                                                     potassium channel activity||cation channel activity
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARIS SALIVARY 0.004 primary transcript processing - RNA bindingBTSP-2 2 B
                                                        s/bt                              35S        RNA binding||nucleic acid binding||binding
                                                                                                                 binding
                                                                    snRNA processing4- BTSP-6 PACIFICUS BTSP 6 BTSP-1 1 GLAND - nucleolus
   1        1    Ixodes scapularis
                            SALIVARY 4 IXODES SCAPULARIS PUTATIVE SECRETED- GLAND BTSP-6 PACIFICUS BTSP RNA bindingBTSP-2 2 B
                                          basic tail protein
                                                        s/bt                           0.006         RNA binding||nucleic acid binding||binding
                                                                                                                 binding
                                                                    snRNA processing 35S primary transcript processing - 6 BTSP-1 1 - nucleolus
   1        1               PUTATIVE SECRETEDtail
                 Ixodes scapularis        basic IXODES SCAPULARIS SALIVARY 0.009potassium channeltransporter activity ion transport 6 B
                                                        s/bt                            4 GLAND BTSP-2 PACIFICUS BTSP 2 BTSP-1 1 BTSP-6
                                                                    integral to membrane -                        activity - potassium
                                                                                                     potassium channel activity||cation channel activity
   1        1               PUTATIVE SECRETEDtail protein IXODES SCAPULARIS 0.098potassium channeltransporter activity ion transport 2 BT
                 Ixodes scapularis        basic SALIVARYs/bt                            GLAND BTSP-1 PACIFICUS BTSP 1 BTSP-6 channel activity
                                                                    integral to membrane -                        activity - potassium
                                                                                                     potassium channel activity||cation 6 BTSP-2
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARIS SALIVARY 0.005
                                                        s/bt                            4 GLAND BTSP-2 PACIFICUS BTSP 2 BTSP-6 6 BTSP-1 1 B
                                                                    physiological process                        transporter activity
                                                                                                     potassium channel activity||cation channel activity
   1        1               SALIVARY GLAND IXODES SCAPULARIS PUTATIVE process
                 Ixodes scapularis        basic tail    s/bt                           0.057         potassium channel activity||cation channel activity
                                                                                                                 transporter 1 4 BTSP-2 2 BTSP-6 6 B
                                                                    physiological SECRETED BTSP-1 PACIFICUS BTSPactivity
   1        1               PUTATIVE SECRETEDtail
                 Ixodes scapularis        basic IXODES SCAPULARIS SALIVARY 0.007 primary transcript processing - RNA bindingBTSP-1 1 B
                                                        s/bt                              35S        RNA binding||nucleic acid binding||binding
                                                                                                                 binding
                                                                    snRNA processing4- GLAND BTSP-2 PACIFICUS BTSP 2 BTSP-6 6 - nucleolus
   1        1               PUTATIVE IXODES SCAPULARIS SECRETED SALIVARY 0.005
                 Ixodes scapularis        basic tail    s/bt                            4 GLAND BTSP-2 PACIFICUS BTSP 2 BTSP-6 6 BTSP-1 1 B
                                                                    negative regulation of body size             catalytic activity
                                                                                                     ATP-dependent DNA helicase activity||DNA-depe
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARIS SALIVARY 0.011 BTSP-6 PACIFICUSDNA helicase activity||DNA-depe
                                                        s/bt                            GLAND
                                                                    physiological process                        catalytic activity
                                                                                                     ATP-dependent BTSP 6 BTSP-2 2 BTSP-1 1 4 B
   1        1    Ixodes scapularis
                            SALIVARY 4 IXODES SCAPULARIS PUTATIVE SECRETED- GLAND BTSP-6 PACIFICUS BTSP RNA bindingBTSP-2 2 B
                                          basic tail protein
                                                        s/bt                           0.009         RNA binding||nucleic acid binding||binding
                                                                                                                 binding
                                                                    snRNA processing 35S primary transcript processing - 6 BTSP-1 1 - nucleolus
   1        1               PUTATIVE SECRETEDtail
                 Ixodes scapularis        basic IXODES SCAPULARIS SALIVARY 0.007
                                                        s/bt                            4 GLAND BTSP-2 PACIFICUS BTSP 2 BTSP-1 1 BTSP-6 6 B
                                                                    physiological process                        transporter activity
                                                                                                     potassium channel activity||cation channel activity
   1        1               SALIVARY SECRETEDtail protein
                 Ixodes scapularis                      s/bt
                                          basic IXODES SCAPULARIS PUTATIVE 4 GLAND BTSP-6 PACIFICUS BTSP 6 BTSP-1 1 BTSP-2 2 B
   1        1    Ixodes scapularis
                            PUTATIVE IXODES SCAPULARIS SECRETED SALIVARY 0.033potassium channeltransporter activity ion transport 2 B
                                          basic tail protein
                                                        s/bt                            GLAND 4 BTSP-6 PACIFICUS BTSP 6 BTSP-1 1 BTSP-2
                                                                    integral to membrane -                        activity - potassium
                                                                                                     potassium channel activity||cation channel activity
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARIS SALIVARY 0.015 BTSP-6 PACIFICUS BTSP 6 activity||mRNA binding||
                                                        s/bt                            GLAND
                                                                    physiological process                        binding
                                                                                                     pre-mRNA splicing factor BTSP-2 2 BTSP-1 1 4 B
   1        1    Ixodes scapularis
                            SALIVARY GLAND IXODES SCAPULARIS PUTATIVE process
                                          basic tail protein
                                                        s/bt                           0.007         DNA binding||nucleic acid binding||binding
                                                                                                                 binding
                                                                    physiological SECRETED BTSP-6 PACIFICUS BTSP 6 BTSP-1 1 BTSP-2 2 4 B
   1        1               PUTATIVE SECRETEDtail protein IXODES SCAPULARIS 0.016 BTSP-6 PACIFICUS BTSPactivity (sensu Animalia)
                 Ixodes scapularis        basic SALIVARYs/bt                            GLAND        potassium channel activity||cation 1 4 BTSP-2 2 B
                                                                                                                 transporter 6 BTSP-1
                                                                    post-embryonic body morphogenesis - embryonic development channel activity
   1        1    Ixodes scapularis
                            PUTATIVE IXODES SCAPULARIS SECRETEDdevelopmentBTSP-10 PACIFICUSgrowth - reproductionBTSP-6 6 BTSP-8
                                          basic tail protein
                                                        s/bt                             (sensu      protein - BTSP 10 GLAND 4
                                                                                                                 binding
                                                                    larval SALIVARY 0.001 Nematoda) binding||binding
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARISdevelopmentGLAND 4 BTSP-10 binding||binding
                                                        s/bt                             (sensu      protein - growth - reproduction
                                                                                                                 binding
                                                                    larval SALIVARY 0.002 Nematoda) PACIFICUS BTSP 10 BTSP-6 6 BTSP-8
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARISdevelopmentBTSP-10 PACIFICUSgrowth - reproductionBTSP-6 6 BTSP-8
                                                        s/bt                             (sensu      protein - BTSP 10 GLAND 4
                                                                                                                 binding
                                                                    larval SALIVARY 0.001 Nematoda) binding||binding
   1        1    Ixodes scapularis
                            PUTATIVE SECRETED with basicSCAPULARISdevelopmentGLAND BTSP-10 PACIFICUS reproduction
                                          salp9 IXODES tail
                                                        s/bt                             (sensu      protein - growth - BTSP
                                                                                                                 binding
                                                                    larval SALIVARY 0.009 Nematoda) binding||binding 10 BTSP-8 BTSP-7 BTS
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARIS SALIVARY 0.026 activity - regulation of transcription, DNA-dependent cof
                                                        s/bt                            GLAND        transcription corepressor 6 BTSP-2 2 BTSP-8 - c
                                                                                                                 transcription regulator activity
                                                                    transcription corepressor 4 BTSP-6 PACIFICUS BTSP activity||transcription BT
   1        1    Ixodes scapularis
                            PUTATIVE IXODES SCAPULARIS SECRETEDdevelopmentBTSP-10 PACIFICUSgrowth - reproductionBTSP-6 6 BTSP-8
                                          salp9 with basic tail
                                                        s/bt                             (sensu      transcription corepressor activity||transcription cof
                                                                                                                 transcription regulator activity
                                                                    larval SALIVARY 0.001 Nematoda) - BTSP 10 GLAND 4
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARISdevelopmentGLAND BTSP-10 PACIFICUS reproductionBTSP-6 6 BTSP-8
                                                        s/bt                             (sensu      molecular_function unknown
                                                                                                                 molecular_function
                                                                    larval SALIVARY 0.001 Nematoda) - growth - BTSP 10 4 unknown
   1        1    Ixodes scapularis
                            PUTATIVE SECRETED with basicSCAPULARISdevelopmentBTSP-10 PACIFICUSgrowth - reproductionBTSP-2 2 BTSP-8
                                          salp9 IXODES tail
                                                        s/bt                             (sensu      molecular_function 4 GLAND
                                                                                                                 molecular_function
                                                                    larval SALIVARY 0.003 Nematoda) - BTSP 10 unknown unknown
   1        1    Ixodes scapularis
                            PUTATIVE SALIVARY IXODES SCAPULARIS SECRETED 0.033 BTSP-6 PACIFICUS-BTSP 6 4 BTSP-2 2 BTSP-8 BT
                                          basic tail protein
                                                        s/bt                             (sensu      molecular_function unknown
                                                                                                                 molecular_function
                                                                    larval developmentGLAND Nematoda) - growth reproduction unknown
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARISdevelopmentBTSP-10 PACIFICUSgrowth - reproductionBTSP-6 6 BTSP-8
                                                        s/bt                             (sensu      protein - BTSP 10 GLAND 4
                                                                                                                 binding
                                                                    larval SALIVARY 0.001 Nematoda) binding||binding
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARISdevelopmentGLAND 4 BTSP-10 binding||binding
                                                        s/bt                             (sensu      protein - growth - reproduction
                                                                                                                 binding
                                                                    larval SALIVARY 0.001 Nematoda) PACIFICUS BTSP 10 BTSP-6 6 BTSP-8
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARISdevelopmentBTSP-10 PACIFICUSgrowth - reproduction unknown
                                                        s/bt                             (sensu      molecular_function GLAND
                                                                                                                 molecular_function
                                                                    larval SALIVARY 0.002 Nematoda) - BTSP 10 unknownBTSP-6 6 BTSP-8 BT
   1        1    Ixodes scapularis
                            PUTATIVE SECRETED with basicSCAPULARISdevelopmentGLAND 4 BTSP-2 PACIFICUS BTSP 2 BTSP-8 BTSP-7 BTS
                                          salp9 IXODES tail
                                                        s/bt                             (sensu      molecular_function unknown
                                                                                                                 molecular_function
                                                                    larval SALIVARY 0.015 Nematoda) - growth - reproduction unknown
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARIS SALIVARY 0.034 activity - regulation of transcription, DNA-dependent cof
                                                        s/bt                            GLAND        transcription corepressor 6 BTSP-2 2 BTSP-8 - c
                                                                                                                 transcription regulator activity
                                                                    transcription corepressor 4 BTSP-6 PACIFICUS BTSP activity||transcription BT
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARISdevelopmentBTSP-6 Nematoda) - BTSP 6-BTSP-8 BTSP-7 GLAND BTSP-
                                                        s/bt        larval SALIVARY 0.001            molecular_function unknown
                                                                                                                 molecular_function
                                                                                         (sensu PACIFICUS growth reproduction unknown
   1        1    Ixodes pacificus
                            BTSP-11 IXODESbasic tail protein
                                           PACIFICUSs/btcys 11 PUTATIVE of protein activity, epigeneticSALIVARY BTSP-9 9 BTSP-2 2 BTSP-6
                                                         BTSP                          0.0002        transporter transporter activity
                                                                                                                 activity
                                                                    regulation SECRETED SCAPULARIS - embryonic development (sensu Animal
  16       52    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARIS SALIVARY 0.007potassium channeltransporter activity ion transport 1 B
                                                        s/bt                            4 GLAND BTSP-6 PACIFICUS BTSP 6 BTSP-2 2 BTSP-1
                                                                    integral to membrane -                        activity - potassium
                                                                                                     potassium channel activity||cation channel activity
   1        1    Ixodes pacificus
                            BTSP-11 IXODESbasic tail protein
                                           PACIFICUSs/btcys 11 SALIVARY SECRETED SCAPULARISbinding||binding
                                                         BTSP                          0.031
                                                                    fatty acid metabolism                        binding
                                                                                                     protein PUTATIVE GLAND 4 BTSP-6 6 BTSP-2
   1        1    Ixodes pacificus
                            BTSP-11 IXODESbasic tail protein - probable splice variantchannel activity - visual perceptionGLAND BTSP-6 6 PREDICTE
                                           PACIFICUSs/bt2 11 PUTATIVE SECRETED SCAPULARIS SALIVARY - integral to plasma membran
                                                         BTSP                          0.074         ligand-gated ion
                                                                                                                 transporter activity
                                                                    ligand-gated ion as it has inserted sequence channel activity||ion channel activ
   1        1    Ixodes pacificus
                            BTSP-11 IXODESDGVCR family 10 kda PUTATIVE SECRETED SCAPULARIS SALIVARYactivity||transcription regulator
                                           PACIFICUSs/btcys 11 transcription factor activity
                                                         BTSP                          0.043                     transcription regulator activity
                                                                                                     transcription factor GLAND 2 PRECURSOR RICI
   1        1    Ixodes scapularis
                            PUTATIVE SECRETEDtail protein
                                          basic IXODES SCAPULARIS SALIVARY 0.002potassium channeltransporter activity ion transport 6 B
                                                        s/bt                            4 GLAND BTSP-1 PACIFICUS BTSP 1 BTSP-2 2 BTSP-6
                                                                    integral to membrane -                        activity - potassium
                                                                                                     potassium channel activity||cation channel activity

   1        1               PUTATIVE IXODES SCAPULARIS ANTICOAGULANT SALP9 SALP11 SALIVARY GLAND SECRETED BTSP-4 PACIFIC
                 Ixodes scapularis                    s/bt
                                          salp11 anticoagulant
   1        1               PUTATIVE IXODES SCAPULARIS ANTICOAGULANT SALP9 SALP11 SALIVARY GLAND SECRETED BTSP-4 PACIFIC
                 Ixodes scapularis                    s/bt
                                          truncated salp9
 1     1              PUTATIVE ANTICOAGULANTs/bt
           Ixodes scapularis                      SALP9 IXODES
                                    putative anticoagulant Salp9 SCAPULARIS SALP11 SALIVARY GLAND SECRETED BTSP-4 PACIFIC
 1     1              PUTATIVE ANTICOAGULANT SALP9 IXODES SCAPULARIS SALP11 BTSP-5 PACIFICUS BTSP 5 BTSP-4 4 SECRETE
           Ixodes scapularis        salp9 YYCWs/bt
 1     1              PUTATIVE ANTICOAGULANT SALP9 IXODES SCAPULARIS SALP11 SECRETED SALIVARY GLAND BTSP-10 PACIFI
           Ixodes scapularis        salp9 YYCWs/bt
 1     1              PUTATIVE ANTICOAGULANT SALP9 IXODES SCAPULARIS SALP11 SECRETED BTSP-5 PACIFICUS BTSP 5 BTSP-4
           Ixodes scapularis        salp9 YYCWs/bt
 1     1              PUTATIVE ANTICOAGULANT SALP9 IXODES SCAPULARIS SALP11 BTSP-10 PACIFICUS BTSP 10 SALIVARY GLAN
           Ixodes scapularis        salp9 YYCWs/bt
 1     1              PUTATIVE ANTICOAGULANT SALP9 IXODES SCAPULARIS SALP11 BTSP-10 PACIFICUS BTSP 10 BTSP-5 5 BTSP-4
           Ixodes scapularis        salp9 YYCWs/bt
 1     1              PUTATIVE ANTICOAGULANT SALP9 IXODES SCAPULARIS SALP11 SECRETED BTSP-10 PACIFICUS BTSP 10 SALI
           Ixodes scapularis        salp9 YYCWs/bt
 1     1              PUTATIVE ANTICOAGULANT SALP9 IXODES SCAPULARIS SALP11 SECRETED BTSP-10 PACIFICUS BTSP 10 SALI
           Ixodes scapularis        salp9 YYCWs/bt
 1     1              PUTATIVE ANTICOAGULANT SALP9 IXODES SCAPULARIS SALP11 BTSP-10 PACIFICUS BTSP 10 BTSP-5 5 BTSP-4
           Ixodes scapularis        salp9 YYCWs/bt
115   14              SAPIENS KERATIN ASSOCIATED HAS BASIC TAIL CYS FRAMEWORK BUT REALLY DOES NOT MATCH 5-9 5.9 U
           Homo sapiens                          s/btcys
                                    4.7 kDa peptide - ULTRA HIGH-SULPHUR SULFER KR59_HUMAN KERATIN-ASSOCIATED
 1     1              PUTATIVE SECRETEDtail protein IXODES SCAPULARIS 4 GLAND BTSP-2 PACIFICUS BTSP 2 BTSP-1 1 BTSP-6 6 B
           Ixodes scapularis                     s/bt
                                    basic SALIVARY



1     1               SALP10         salp10 family s/kun monolaris
           Ixodes scapularis IXODES SCAPULARIS PUTATIVE SECRETED SALIVARY 2 SIMILAR TO HYPOTHETICAL RATTUS NORVEG
1     1               PUTATIVE SECRETED IXODESpeptide
           Ixodes scapularis                       s/kun monolaris
                                     Kunitz domain SCAPULARIS SALP10 SALIVARY 2 PROTEASE INHIBITOR ISL1156_CLUSTER318 T
1     1               PUTATIVE SECRETED IXODESpeptide
           Ixodes scapularis                       s/kun monolaris
                                     Kunitz domain SCAPULARIS SALP10 SALIVARY 2 PROTEASE INHIBITOR ISL1156_CLUSTER318 T
1     1               SALP10         Salp10 family/kun monolaris
                                                   s           embryonic development (sensu Animalia) INHIBITOR ISL1156_CLUSTER318 C
                                                                                  0.044
           Ixodes scapularis IXODES SCAPULARIS PUTATIVE SECRETED SALIVARY 2 PROTEASE - larval development (sensu Nematoda
1     1               PUTATIVE SECRETED IXODESpeptide
           Ixodes scapularis                       s/kun monolaris
                                     Kunitz domain SCAPULARIS SALP10 SALIVARY 2 PROTEASE INHIBITOR ISL1156_CLUSTER318 S
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODESpeptide embryonic development (sensu Animalia) - larval development (sensu Nematoda
                                     Kunitz domain SCAPULARIS SALP10 SALIVARY 2 PROTEASE enzyme regulator activity
                                                   s/kun monolaris               0.0001         endopeptidase inhibitor ISL1156_CLUSTER318 T
                                                                                                            INHIBITOR activity||protease inhibitor
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODESpeptide embryonic development (sensu Animalia) - larval development (sensu Nematoda
                                     Kunitz domain SCAPULARIS SALP10 SALIVARY 2 PROTEASE enzyme regulator activity
                                                   s/kun monolaris               0.0002         endopeptidase inhibitor ISL1156_CLUSTER318 T
                                                                                                            INHIBITOR activity||protease inhibitor
1     1    Ixodes scapularis
                      SALIVARY 2 IXODES SCAPULARISmonolaris SECRETED SALP10 PROTEASE enzyme regulator activity
                                     Salp10 family/kun PUTATIVE
                                                   s           basement membrane  0.007                     INHIBITOR activity||protease inhibitor
                                                                                                endopeptidase inhibitor ISL1156_CLUSTER318 K
1     1               PUTATIVE SECRETED IXODES SCAPULARIS SALP10 SALIVARY 2 PROTEASE INHIBITOR ISL1156_CLUSTER318 B
           Ixodes scapularis                       s/kun
                                     bungarotoxin-like monolaris
1     1               PUTATIVE SECRETED IXODES SCAPULARIS SALP10 SALIVARY 2 PROTEASE INHIBITOR ISL1156_CLUSTER318 B
           Ixodes scapularis                       s/kun
                                     bungarotoxin-like monolaris
1     1               PUTATIVE SECRETED IXODESpeptide basement membrane
           Ixodes scapularis                       s/kun monolaris                0.026
                                     Kunitz domain SCAPULARIS SALP10 SALIVARY 2 PROTEASE INHIBITOR ISL1156_CLUSTER318 B
1     1               PUTATIVE SECRETED IXODES SCAPULARIS SALP10 SALIVARY 2 PROTEASE INHIBITOR ISL1156_CLUSTER318 C
           Ixodes scapularis                       s/kun
                                     similar to Salp10 monolaris
1     1    Ixodes scapularis
                      PUTATIVE SECRETED PROTEASEmonolaris 2 ISL1156_CLUSTER318 IXODES SCAPULARIS TOXIN 1 ARANEUS VE
                                     Kunitz domain peptide serine-type endopeptidase inhibitor activityenzyme regulator activity
                                                   s/kun INHIBITOR                1E-12         serine-type endopeptidasematrix structural consti
                                                                                                             - extracellular inhibitor activity||endop
1     1    Ixodes scapularis
                      PUTATIVE SECRETED Kunitzs/kun monolaris 2 ISL1156_CLUSTER318 Animalia)SCAPULARIS KUNITZ-LIKE Nematoda
                                     single PROTEASE INHIBITOR
                                                    peptide embryonic development (sensu IXODES -endopeptidase inhibitor activity||endop
                                                                                  4E-13                      larval development (sensu PRECUR
                                                                                                serine-type enzyme regulator activity
1     1               PUTATIVE SECRETED IXODES SCAPULARIS SALIVARY 0.003 PACIFICUS binding||binding
           Ixodes scapularis         Kunitz 8      s/kun monolaris 2
                                                               basement membrane   KUN-6                    binding
                                                                                                protein KUN 6 PROTEASE INHIBITOR ISL1156_
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS SALIVARY 0.081 PACIFICUS binding||binding
                                     Kunitz 7.1 s/kun monolaris 2 binding - transforming growth factor beta receptor signaling pathway
                                                               protein             KUN-6        protein KUN 6 PROTEASE INHIBITOR ISL1156_
                                                                                                            binding
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODESpeptide embryonic development (sensuINHIBITOR positiveregulator activity KUN-6 PAC
                                     Kunitz domain SCAPULARIS SALIVARY PROTEASEendopeptidase inhibitor activity||protease rate - lar
                                                   s/kun monolaris 2             0.0008          Animalia) - ISL1156_CLUSTER318
                                                                                                            enzyme regulation of growth inhibitor
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS KUN-6 PACIFICUS KUN type VI
                                     Similar to I. pacificus KUN-6 2 development - collagenprotein binding||binding
                                                   s/kun monolaris
                                                               muscle            0.0002                     binding
                                                                                                 6 SALIVARY ANOPHELES GAMBIAE STR. PE
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS KUN-6 PACIFICUS KUN 6 SALIVARY PROTEASE INHIBITOR ISL1156_
                                     Similar to I. pacificus KUN-6 5
                                                   s/kun monolaris
                                                               basement membrane  0.001                     binding
                                                                                                protein binding||binding
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS KUN-6 PACIFICUS KUN 6 SALIVARY PROTEASE INHIBITOR ISL1156_
                                     Similar to I. pacificus KUN-6 5
                                                   s/kun monolaris
                                                               basement membrane 0.0004                     enzyme regulator activity
                                                                                                endopeptidase inhibitor activity||protease inhibitor
1     1               PUTATIVE SECRETED IXODES SCAPULARIS KUN-6 PACIFICUS KUN 6 SALIVARY LACUNIN MANDUCA SEXTA HYP
           Ixodes scapularis         Kunitz 8.2 s/kun monolaris 5
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODESpeptide embryonic development (sensu Animalia) - larval development (sensu Nematoda
                                     Kunitz domain SCAPULARIS KUN-6 PACIFICUS KUN 6 SALIVARY HYPOTHETICAL CAENORHABDI
                                                   s/kun monolaris 5              0.001         protein binding||binding
                                                                                                            binding
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODESpeptide extracellular space
                                     Kunitz domain SCAPULARIS KUN-6 PACIFICUS KUN 6 SALIVARY PROTEASE INHIBITOR ISL1156_
                                                   s/kun monolaris 5            0.000004        protein binding||binding
                                                                                                            binding
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS Kunitzspace
                                     putative secreted peptide with KUN-6domain
                                                   s/kun monolaris 5
                                                               extracellular PACIFICUS KUN 6 SALIVARY PROTEASE INHIBITOR ISL1156_
                                                                                0.000004                    binding
                                                                                                protein binding||binding
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIScoagulation 0.004 KUN 6 SALIVARY KUN-1 1 activity||protease inhibitor
                                     putative secreted peptide with Kunitz domain
                                                   s/kun monolaris 5 KUN-6 PACIFICUS
                                                               blood              - endopeptidase inhibitor activity regulator activity INHIBITOR
                                                                                                            enzyme
                                                                                                endopeptidase inhibitor PROTEASE
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS KUN-6 PACIFICUS KUN 6 SALIVARY PROTEASE INHIBITOR ISL1156_
                                     Kunitz 6.6 s/kun monolaris 5
                                                               basement membrane0.00004                     binding
                                                                                                protein binding||binding
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS KUN-6 PACIFICUS KUN Animalia) -endopeptidase inhibitor activity||endop
                                     Similar to I. pacificus KUN-6 5
                                                   s/kun monolaris
                                                               embryonic development (sensu 6 SALIVARY IBP_CARCR CHELONIANIN BAS
                                                                                  0.002                      positive regulation of growth rate - lar
                                                                                                serine-type enzyme regulator activity
1     1               PUTATIVE SECRETED IXODES SCAPULARIS KUN-6 PACIFICUS KUN 6 SALIVARY HYPOTHETICAL CAENORHABDI
           Ixodes scapularis                       s/kun monolaris
                                     Similar to I. pacificus KUN-6 5
1     1               PUTATIVE SECRETED IXODES SCAPULARIS KUN-6 PACIFICUS KUN 6 SALIVARY HYPOTHETICAL extracellular
           Ixodes scapularis                       s/kun monolaris
                                                               mechanosensory behavior - response to mechanical stimulus - CAENORHABDI
                                     Similar to I. pacificus KUN-6 5              0.003
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS KUN-6 PACIFICUS KUN Animalia) - positiveregulator activity
                                     Kunitz 7.2 s/kun monolaris 5
                                                               embryonic development (sensu 6 SALIVARY PROTEASE INHIBITOR ISL1156_
                                                                                0.00008                     enzyme regulation of growth inhibitor
                                                                                                endopeptidase inhibitor activity||protease rate - lar
1     1               KUN-6
           Ixodes pacificus IXODES PACIFICUS KUN 6 PUTATIVE SECRETED SCAPULARIS DROSOPHILA PSEUDOOBSCURA ANOPHE
                                     Kunitz 6.7 s/kun monolaris 5
                                                               basement membrane0.00006                     enzyme regulator activity
                                                                                                endopeptidase inhibitor activity||protease inhibitor
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIScoagulation - endopeptidasePROTEASEinhibitor activity||protease inhibitor
                                     putative secreted peptide with Kunitz domain
                                                   s/kun monolaris 5 KUN-6 PACIFICUS KUN 6 inhibitor activity regulator activity
                                                               blood tfpi       0.00004         endopeptidase INHIBITOR ISL1156_CLUSTER3
                                                                                                            enzyme
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODESpeptide basement membrane
                                     Kunitz domain SCAPULARIS KUN-6 PACIFICUS KUN 6 ISOFORM A DROSOPHILA MELANOGASTE
                                                   s/kun monolaris 5             0.0001         serine-type enzyme regulator activity
                                                                                                            endopeptidase inhibitor activity||endop
1     1    Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS KUN-6 PACIFICUS KUN 6 SALIVARY BOOPHILIN BOOPHILUS MICRO
                                     Kunitz 6.7 s/kun monolaris 5
                                                               basement membrane 0.0009                     binding
                                                                                                protein binding||binding
1     1               PUTATIVE SECRETED IXODES SCAPULARIS KUN-6 PACIFICUS KUN 6 SALIVARY HYPOTHETICAL CAENORHABDI
           Ixodes scapularis                       s/kun monolaris
                                     Similar to I. pacificus KUN-6 6
1     1               PUTATIVE SECRETED IXODES SCAPULARIS Kunitz domain
           Ixodes scapularis                       s/kun monolaris 6
                                     putative secreted peptide with KUN-6 PACIFICUS KUN 6 SALIVARY TROPHOBLAST KUNITZ DOMAIN
1     1               PUTATIVE SECRETED IXODES SCAPULARIS Kunitz domain
           Ixodes scapularis                       s/kun monolaris 6
                                                               basement membrane  0.096
                                     putative secreted peptide with KUN-6 PACIFICUS KUN 6 ANOPHELES GAMBIAE STR. PEST MULGIN
1     1               PUTATIVE SECRETED IXODES SCAPULARIS KUN-6 PACIFICUS KUNmembrane
           Ixodes scapularis                       s/kun monolaris
                                                               extracellular space - integral to 6 HYPOTHETICAL CAENORHABDITIS ELEGA
                                     Similar to I. pacificus KUN-6 6              0.074
1     1               PUTATIVE 8.4 KDA SECRETED IXODESembryonic 4
           Ixodes scapularis                       s/Kun-ACR monolaris
                                                                SCAPULARIS 8.0 PACIFICUS 7.9 HYPOTHETICAL CAENORHABDITIS BRIG
                                                                                  0.015
                                     putative 8.1 kDa secreted protein development (sensu Animalia) - positive regulation of growth rate - lar
1     1               PUTATIVE 8.4 KDA SECRETED motif peptide
           Ixodes scapularis                       s/Kun-ACR SCAPULARIS 8.0 PACIFICUS 7.9 HYPOTHETICAL CAENORHABDITIS BRIG
                                     ADAM cys-rich IXODES monolaris 4
1     1               PUTATIVE 8.4 KDA SECRETED IXODESembryonicof 8.68.0 PACIFICUS Animalia) - positive regulation of growth rate - lar
           Ixodes scapularis                       s/Kun-ACR monolaris development (sensu 7.9 HYPOTHETICAL CAENORHABDITIS BRIG
                                                                SCAPULARIS kDa
                                     putative secreted salivary peptide 4         0.015
1     1               PUTATIVE SECRETED IXODES SCAPULARIS SALP10 SALIVARY 2 PROTEASE INHIBITOR ISL1156_CLUSTER318 D
           Ixodes scapularis                       s/Kun-salp10
                                     similar to Salp10
1     1               PUTATIVE SECRETED peptide/Kun-salp10
           Ixodes scapularis                       s
                                     9 kDa IXODES SCAPULARIS SALIVARY 2 SALP10 PROTEASE INHIBITOR ISL1156_CLUSTER318 S
1     1               PUTATIVE SECRETED IXODES SCAPULARIS SALP10 SALIVARY 2 PROTEASE INHIBITOR ISL1156_CLUSTER318 P
           Ixodes scapularis         8.4 kD peptides/Kun-salp10
1     1               PUTATIVE SECRETED IXODES SCAPULARIS Kunitz domain
           Ixodes scapularis                       s/kun-4Cys
                                     putative secreted peptide with SALIVARY KUN-6 PACIFICUS KUN 6 LACUNIN MANDUCA SEXTA UNK
1     1               PUTATIVE SECRETED IXODESpeptide
           Ixodes scapularis                       s/kun-4Cys-CC
                                     Kunitz domain SCAPULARIS SALIVARY KUN-6 PACIFICUS KUN 6 LACUNIN MANDUCA SEXTA KUN
1     1               PUTATIVE SALIVARY SECRETED IXODES SCAPULARIS KUN-6 PACIFICUS KUN 6 CLSP-1 CLSP 1 CLSP-5 5 VARIA
           Ixodes scapularis                        peptide
                                     single Kunitzs/kun-4Cys
1     1    Ixodes scapularis
                      PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS DROSOPHILAregulation of growth rate - lar
                                     Kunitz 8.5 s/kun monolaris 8.5 development (sensu Animalia) - positive PSEUDOOBSCURA MELA
                                                               embryonic         0.0005         protein binding||binding
                                                                                                            binding
1     1    Ixodes scapularis
                      PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS DROSOPHILAregulation of growth PSEUDO
                                     Kunitz 8.5 s/kun monolaris 8.5 development (sensu Animalia) - positive MELANOGASTER rate - lar
                                                               embryonic         0.0005         protein binding||binding
                                                                                                            binding
1     1    Ixodes scapularis
                      PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS DROSOPHILAregulation of growth rate - lar
                                     Kunitz domain peptide embryonic development (sensu Animalia) - positive PSEUDOOBSCURA MELA
                                                   s/kun monolaris 8.5           0.0005         protein binding||binding
                                                                                                            binding
 1      1              PUTATIVE SECRETED IXODES SCAPULARIS SALIVARY 0.098 (sensu Animalia) - larval development (sensu Nematoda
            Ixodes scapularis                        s/kun monolaris
                                                                 embryonic development PACIFICUS KUN 6 PROTEASE INHIBITOR ISL1156_
                                       Similar to I. pacificus KUN-6 7             KUN-6
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS SALIVARY 0.057 PACIFICUS KUN 6 PROTEASE INHIBITOR ISL1156_
                                       Similar to I. pacificus KUN-6 7
                                                     s/kun monolaris
                                                                 ubiquitin-dependent protein catabolism binding||transition metal ion binding||meta
                                                                                   KUN-6        zinc ion   binding
 1      1              PUTATIVE SECRETED IXODESpeptide basement membrane
            Ixodes scapularis                        s/kun tfpi                   0.007
                                       Kunitz domain SCAPULARIS KUN-6 PACIFICUS KUN 6 PROTEINASE INHIBITOR 5.II SNAKE-LOCKS
 1      1              PUTATIVE SECRETED IXODESpeptide basement membrane
            Ixodes scapularis                        s/kun tfpi                   0.005
                                       Kunitz domain SCAPULARIS KUN-6 PACIFICUS KUN 6 PROTEINASE INHIBITOR 5.II SNAKE-LOCKS
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODESpeptide basement membrane
                                       Kunitz domain SCAPULARIS SALP10 SALIVARY 2 PROTEASE enzyme regulator activity
                                                     s/Kun-salp10                 0.001         endopeptidase inhibitor ISL1156_CLUSTER318 T
                                                                                                           INHIBITOR activity||protease inhibitor
 1      1              PUTATIVE SECRETED IXODES SCAPULARIS SALIVARY 0.003 - collagen typeKUN 6 PROTEASE INHIBITOR ISL1156_
            Ixodes scapularis          Kunitz 8      s/kun-4Cys-CC
                                                                 epidermis development PACIFICUS VII enzyme regulator activity
                                                                                   KUN-6                    - basement activity||protease inhibitor
                                                                                                endopeptidase inhibitor membrane
 5      3   Ixodes scapularis
                       PUTATIVE SECRETED PROTEASEYGGC
                                       Kunitz 8.7 s/kun INHIBITOR ISL1156_CLUSTER318 IXODES SCAPULARIS MCPI_MELCP MCAPI in
                                                                 DNA binding - G-protein coupled receptor protein signaling pathway - nucleus - C
                                                                                  0.0005        DNA binding||nucleic acid binding||binding
                                                                                                           binding
40     11              ISOAMYLASE FAMILY GEOBACTER SULFURREDUCENS PCA UNNAMED PRODUCT TETRAODON NIGROVIRIDIS P
                                       putative 8.4 kDa family member 4 - distant
            Geobacter sulfurreducens PCA             s/Kun-ACR monolaris
 1      1              PUTATIVE SECRETED SALIVARYtissue factor pathway inhibitor
            Ixodes scapularis                        s/kun tfpi
                                       weakly similar to GLAND PEPTIDE IXODES SCAPULARIS CO3_LAMJA COMPLEMENT C3 PRECUR
 1      1              PUTATIVE SECRETED IXODES SCAPULARIS SALP10 SALIVARY 2 PROTEASE INHIBITOR ISL1156_CLUSTER318 B
            Ixodes scapularis                        s
                                       Salp10 family/Kun-salp10

  1     1               KUN-5          Kunitz 13.5 s/kun ixolaris FACTOR PATHWAY INHIBITOR B DANIOinhibitor activity||protease inhibitor
                                                                extracellular 2 1E-17
            Ixodes pacificus IXODES PACIFICUS KUN 5 TISSUE monolaris space                                   enzyme regulator activity
                                                                                                endopeptidase RERIO NOVEL SIMILAR TO HU
  1     1               PUTATIVE SECRETED 15
            Ixodes scapularis          Kuniz IXODES SCAPULARIS KUN-4 PACIFICUS KUN 4 KUN-3 3 KUN-2 2 HYPOTHETICAL inhibitor a
                                                     s/kun15                      0.0009        calcium channel inhibitor activity||ion channel inhi
                                                                                                             transporter binding
                                                                calcium channel inhibitor activity - IgA binding - heme activity - trypsin XENOPU
  1     1               IXOLARIS-1 IXODES PACIFICUS IXOLARISmonolaris 2 - transforming growth factor beta receptor signaling pathway
            Ixodes pacificus                                    protein binding 3E-15           protein binding||binding
                                                                                                             binding
                                       ixolaris-1b s/kun ixolaris 1 SCAPULARIS PUTATIVE SECRETED WFIKKN2 HOMO SAPIENS MULT
  1     1   Ixodes scapularis
                        IXOLARIS IXODES SCAPULARIS PUTATIVE SECRETEDtransforming growth factor 1 TISSUE FACTOR PATHWAY INH
                                       ixolaris                 protein binding 2E-16           protein binding||binding
                                                                                                             binding
                                                     s/kun ixolaris monolaris 2 - IXOLARIS-1 PACIFICUS beta receptor signaling pathway
  1     1   Ixodes scapularis
                        PUTATIVE SECRETED IXODES SCAPULARIS IXOLARIS IXOLARIS-1 PACIFICUS 1 UNNAMED PRODUCT TETRAOD
                                       ixolaris family/kun ixolaris monolaris 2 8E-15 (sensu Animalia) - larval development (sensu Nematoda
                                                     s          embryonic development           endopeptidase inhibitor activity||protease inhibitor
                                                                                                             enzyme regulator activity
  1     1               IXOLARIS-2 IXODES PACIFICUS IXOLARISmonolaris 2 1E-17CAENORHABDITISlarval development (sensu Nematoda
            Ixodes pacificus                                    embryonic development           calcium channel inhibitor activity||ion channel inhi
                                                                                                             transporter activity
                                       Kunitz 17 s/kun ixolaris 2 HYPOTHETICAL (sensu Animalia) - ELEGANS PAPILIN ISOFORM A D
  1     1               IXOLARIS-2 IXODES PACIFICUS IXOLARISmonolaris 2 9E-17CAENORHABDITISlarval development (sensu Nematoda
            Ixodes pacificus                                    embryonic development           endopeptidase inhibitor PAPILIN ISOFORM A D
                                                                                                             enzyme regulator activity
                                       Kunitz 18 s/kun ixolaris 2 HYPOTHETICAL (sensu Animalia) - ELEGANSactivity||protease inhibitor
  1     1               IXOLARIS-2 IXODES PACIFICUS IXOLARISmonolaris 2 5E-16CAENORHABDITISlarval development (sensu Nematoda
            Ixodes pacificus                                    embryonic development           endopeptidase inhibitor PAPILIN ISOFORM A D
                                                                                                             enzyme regulator activity
                                       Kunitz 18 s/kun ixolaris 2 HYPOTHETICAL (sensu Animalia) - ELEGANSactivity||protease inhibitor
  1     1               IXOLARIS-2 IXODES PACIFICUS IXOLARISmonolaris 2 A DROSOPHILA MELANOGASTER B HYPOTHETICAL CAEN
            Ixodes pacificus                                    embryonic development           protein binding||binding
                                                                                                             binding
                                       Kunitz 18 s/kun ixolaris 2 ISOFORM 6E-17 (sensu Animalia) - larval development (sensu Nematoda
  1     1   Ixodes pacificus
                        IXOLARIS-2 IXODES PACIFICUS IXOLARIS 22
                                       Kunitz domain peptide basement membrane
                                                     s/kun monolaris ISOFORM A DROSOPHILA MELANOGASTER B EXTRACELLULAR MAT
                                                                                  1E-16                      binding
                                                                                                protein binding||binding
1667   35   Apis mellifera
                        SIMILAR TO MELLIFERA ISOFORM A DROSOPHILA MELANOGASTER B PSEUDOOBSCURA activity||ion channel MAT
                                       Kunitz 22 s/kun22                       0.00000008
                                                                basement membrane                            transporter activity
                                                                                                calcium channel inhibitor EXTRACELLULAR inhi

  1     1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS KUN-1 PACIFICUS KUN 1 KUN-4 4endopeptidase inhibitor activity||endop
                                      Kunitz 27 s/kun27                   2E-15
                                                            basement membrane                  KUN-2 regulator activity
                                                                                  serine-type enzyme 2 KUNITZ-LIKE PROTEASE
1673   23              ISOFORM A
            Drosophila melanogasterDROSOPHILA MELANOGASTER B EXTRACELLULAR MATRIX PAPILIN inhibitor activity||protease inhibitor
                                      Kunitz 31 s/kun YGGC                3E-23
                                                            basement membrane                 enzyme regulator MANDUCA SEXTA
                                                                                  endopeptidase 3 2 LACUNIN activity
  1     1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS KUN-1 PACIFICUS KUN 1 KUN-4 4 KUN-2 2 KUNITZ-LIKE PROTEASE
                                      Kunitz 34 s/kun penthalaris
                                                            basement membrane
                                                                          2E-14               binding
                                                                                  protein binding||binding
  9     9   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS KUN-4 PACIFICUS KUN 4 KUN-2 2 KUN-1 1 KUNITZ-LIKE PROTEASE
                                      Kunitz 34 s/kun penthalaris
                                                            basement membrane
                                                                          8E-26               enzyme regulator activity
                                                                                  endopeptidase inhibitor activity||protease inhibitor
  1     1              KUN-4
            Ixodes pacificus IXODES PACIFICUS KUN 4 PUTATIVE SECRETED SCAPULARIS KUN-2 2endopeptidase inhibitor activity||endop
                                      Kunitz 35 s/kun penthalaris
                                                            basement membrane
                                                                          5E-12                KUN-1 regulator activity
                                                                                  serine-type enzyme 1 KUNITZ-LIKE PROTEASE
  1     1   Ixodes scapularis
                       PUTATIVE SECRETED IXODESpeptide basement membrane
                                      Kunitz domain SCAPULARIS KUN-4 PACIFICUS KUN 4 KUN-2 2endopeptidase inhibitor activity||endop
                                                 s/kun penthalaris        4E-14   serine-type enzyme 1 KUNITZ-LIKE PROTEASE
                                                                                               KUN-1 regulator activity
  1     1   Ixodes scapularis
                       PUTATIVE SECRETED IXODESpeptide basement membrane
                                      Kunitz domain SCAPULARIS KUN-1 PACIFICUS KUN 1 KUN-4 4endopeptidase inhibitor MELLIFERA D
                                                 s/kun penthalaris        4E-19   serine-type enzyme 2 SIMILAR TO activity||endop
                                                                                               KUN-2 regulator activity
  1     1   Ixodes scapularis
                       PUTATIVE SECRETED IXODESpeptide basement membrane
                                      Kunitz domain SCAPULARIS KUN-1 PACIFICUS KUN 1 KUN-4 4endopeptidase inhibitor activity||endop
                                                 s/kun penthalaris        3E-15   serine-type enzyme regulator activity KUN-2 2 K
                                                                                               SIMILAR TO MELLIFERA

96     24   Mus musculus
                       KERATIN COMPLEX 1 ACIDIC GENE 10 structural constituent of cytoskeleton - epidermis developmentactivity
                                          Gly rich peptide
                                                       s/Gly-Pro rich                 0.00002         PRODUCTstructural of cytoskeleton||structural in
                                                                                                                  EPIDERMAL MOUSE SUBUNIT EMB
                                                                     MUS MUSCULUS UNNAMED structural constituent molecule - cytoskeleton - m
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS CLSP-11 PACIFICUS CLSP 11 CLSP-2 2 ~ 4 kDa 9 binding||binding
                                          Gly-Pro-Richs/Gly-Pro rich mucin like peptide of maturesugar binding||carbohydrate CLSP-1 1 CLSP-3 3
                                                         collagen like
                                                                    locomotory behavior0.0004                    binding
                                                                                                      molecular weight CLSP-9
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS CLSP-11 PACIFICUS CLSP 11 CLSP-9 9 ~ 4molecule activity CLSP-3 3
                                          Gly-Pro-Richs/Gly-Pro rich mucin type peptide of maturestructural constituent of cuticle||structural molecul
                                                         collagen like
                                                                    collagen like IV - 0.006          molecular weight CLSP-2
                                                                                                                 structural
                                                                                        membrane - basement membrane kDa 2 CLSP-1 1
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP 1 CLSP-9 9 CLSP-2 regulator activity
                                          Gly-Pro-Richs/Gly-Pro rich mucin type peptide of maturetranscription factor~ 4 kDa CLSP-11 11 CLSP-3 3
                                                         collagen like
                                                                    collagen like IV - 0.007          molecular weight activity||transcription regulator
                                                                                                                 transcription
                                                                                        membrane - basement membrane 2
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP 1 CLSP-2 2 CLSP-9 9 CLSP-11 11 CLSP-3 3
                                          Gly-Pro-Richs/Gly-Pro rich mucindevelopment ofcollagenmolecular weight ~ 4 kDa binding||binding
                                                         collagen like
                                                                    skeletal like peptide - maturesugar binding||carbohydrate
                                                                                       0.0002                    binding
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP (sensuconstituent molecule activity CLSP-8 8
                                          proline serine rich peptide
                                                       s/Gly-Pro rich
                                                                    extracellular - cuticle biosynthesis 1 CLSP-3 3 CLSP-2 cuticle||structural molecul
                                                                                        0.001                    structural of 2 CLSP-11 11
                                                                                                     structural Nematoda) - structural constituent of c
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS CLSP-2 PACIFICUS CLSP 2 CLSP-11 11 ~ 4 kDa 1 CLSP-9 9 CLSP-8 8
                                          Gly-Pro-Richs/Gly-Pro rich mucin like peptide of maturetranscription regulator activity body size - embryon
                                                         collagen like
                                                                    post-embryonic body morphogenesis - positive regulation of
                                                                                       0.0004                    transcription regulator activity
                                                                                                      molecular weight CLSP-1
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS CLSP-9 PACIFICUS CLSP 9 CLSP-2 2 CLSP-11 11 CLSP-1 1 CLSP-8 8
                                          Gly-Pro-Richs/Gly-Pro rich mucin like peptide of matureextracellular matrix structural constituent||structura
                                                         collagen like
                                                                    locomotory behavior 0.005                    structural kDa
                                                                                                      molecular weight ~ 4molecule activity
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS CLSP-11 PACIFICUS CLSP 11 CLSP-2 2 ~ 4 kDa 9 binding||binding
                                          Gly-Pro-Richs/Gly-Pro rich mucin like peptide of maturesugar binding||carbohydrate CLSP-1 1 CLSP-3 3
                                                         collagen like
                                                                    locomotory behavior0.0004                    binding
                                                                                                      molecular weight CLSP-9
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP (sensuconstituent molecule activity CLSP-9 9
                                          Gly-Pro-Richs/Gly-Pro rich mucin like-peptide biosynthesis 1 CLSP-3 3 CLSP-2 cuticle||structural molecul
                                                         collagen like
                                                                    extracellular cuticle of maturestructural Nematoda) kDa CLSP-11 11
                                                                                        0.003                    structural - 2
                                                                                                      molecular weight ~ 4of structural constituent of c
988    15              PERICARDINE Proline rich peptide MELANOGASTER CG5700-PBheart development structural molecule activity conferrin
            Drosophila melanogaster DROSOPHILAs/Gly-Pro rich                           0.0005        extracellular matrix structural constituent
                                                                    extracellular matrix - FIBRONECTIN-BINDING PRECURSOR STAPHYLOCOC
 1      1   Ixodes pacificus
                       CLSP-9 IXODES PACIFICUS CLSP 9 CLSP-2 2 CLSP-11 11 CLSP-1 1 CLSP-3activity||serine-type endopeptidase activity
                                          Gly-Pro-Richs/Gly-Pro rich mucin like peptide of maturetrypsin 3 PUTATIVEregulation of growth rate - m
                                                         collagen like
                                                                    embryonic development (sensu molecular - positiveactivity
                                                                                       0.0003                    catalytic kDa
                                                                                                       Animalia) weight ~ 4 SECRETED SCAPULARIS
 1      1   Ixodes pacificus
                       CLSP-2 IXODES PACIFICUS CLSP 2 CLSP-11 11 like peptide of maturestructural constituentPUTATIVE SECRETED SCA
                                          Gly-Pro-Richs/Gly-Pro rich mucin CLSP-9 0.001
                                                         collagen like
                                                                    hermaphrodite genital morphogenesis 4 CLSP-3 ~ 4molecule activity
                                                                                                      molecular weight 3 of cuticle||structural molecul
                                                                                        9 CLSP-1 1 CLSP-4        structural kDa
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS CLSP-11 body of maturetranscription regulator kDa 2 CLSP-9 9 CLSP-3 3
                                          Gly-Pro-Richs/Gly-Pro rich mucin like peptide morphogenesis - CLSP-1 regulation of body size - locomoto
                                                         collagen like
                                                                    post-embryonic PACIFICUS CLSP 11 positive 1 ~ 4 activity
                                                                                        0.043                    transcription regulator activity
                                                                                                      molecular weight CLSP-2
40     25              BINDIN PRECURSORrich peptide
            Echinometra mathaei           Pro ECHINOMETRA MATHAEI PUTATIVE SECRETED IXODEStranscription regulator activity
                                                       s/Gly-Pro rich
                                                                    transcription factor activity
                                                                                        0.043                       factor activity||transcription regulator
                                                                                                     transcriptionSCAPULARIS CLSP-1 PACIFICUS C
119    20   Canis familiaris
                       PREDICTED HYPOTHETICALs/Gly-Pro rich
                                          4.4 kDa Gly rich peptidetranscription factor activity - transcription cofactor activity - neurogenesis
                                                         CANIS FAMILIARIS CGBO7S COLLAGEN ALPHA 1transcription regulator activity
                                                                                        0.015        transcription III CHAIN BOVINE CA13_BOVIN CO
                                                                                                                    factor activity||transcription regulator
 1      1   Ixodes pacificus
                       CLSP-2 IXODES PACIFICUS CLSP 2 CLSP-11 11 like peptide of matureprotein serine/threonine kinase activity||protein kin
                                          Gly-Pro-Richs/Gly-Pro rich mucin CLSP-9 0.002 (sensu molecular - positiveactivity
                                                         collagen like
                                                                    embryonic development              Animalia) weight ~ 4 SECRETED SCAPULARIS
                                                                                                                 catalytic kDa
                                                                                        9 CLSP-1 1 CLSP-3 3 PUTATIVEregulation of growth rate - m
 1      1   Ixodes pacificus
                       CLSP-1 IXODES PACIFICUS peptide CLSP-6 6 CLSP-10 10 CLSP-8 8 CLSP-5 5 CLSP-7 7unknown 3 CLSP-11 11 CLSP
                                          Proline rich CLSP 1 rich
                                                       s/Gly-Pro embryonic development (sensu Animalia) - hermaphrodite genital morphogenesi
                                                                                     0.0000003                   molecular_function
                                                                                                     molecular_function CLSP-3 unknown
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP 1 CLSP-9 9 CLSP-11 11 CLSP-2 2 CLSP-3 3
                                          Gly-Pro-Richs/Gly-Pro rich mucin like peptide of maturestructural constituent molecule activity - locomoto
                                                         collagen like
                                                                    post-embryonic body morphogenesis - positive regulation of body size molecul
                                                                                        0.086                    structural kDa
                                                                                                      molecular weight ~ 4of cuticle||structural
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP 1 CLSP-11 11 ~structural CLSP-2 2 CLSP-3 3
                                          Gly-Pro-Richs/Gly-Pro rich mucin type peptide of matureextracellular matrixCLSP-9 9 constituent||structura
                                                         collagen like
                                                                    collagen like IV -0.0004          molecular weight 4 kDa
                                                                                                                 structural
                                                                                        membrane - basement membranemolecule activity
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS CLSP-2 PACIFICUS CLSP 2 CLSP-11 11 ~activity 1 CLSP-9 9 CLSP-3 3
                                          Gly-Pro-Richs/Gly-Pro rich mucin like peptide of maturestructural molecule 4molecule activity
                                                         collagen like
                                                                    locomotory behavior 0.001                    structural kDa
                                                                                                      molecular weight CLSP-1
216    14              UNNAMED            Proline rich peptide rich
                                                       s/Gly-Pro skeletal development - collagen type XII constituent molecule activity
                                                                                       0.0001        structural structural of cuticle||structural molecul
            Tetraodon nigroviridis PRODUCT TETRAODON NIGROVIRIDIS HYPOTHETICAL CAENORHABDITIS BRIGGSAE XENOPUS LAEV
 1      1              CLSP-11 IXODESProline rich peptide 11rich
            Ixodes pacificus                             CLSP
                                           PACIFICUSs/Gly-Pro CLSP-7 7 CLSP-6 6 CLSP-5 5 CLSP-10 10 CLSP-3 3 CLSP-8 8 CLSP-1 1 PRED
 1      1   Ixodes pacificus
                       CLSP-1 IXODES PACIFICUS peptide CLSP-3 3 CLSP-6 60.00004 7 CLSP-8 8 CLSP-5 5 CLSP-10 10cellular_component
                                          Proline rich CLSP 1 rich
                                                       s/Gly-Pro molecular_function unknown - biological_process unknown - CLSP-11 11 CLSP
                                                                                        CLSP-7                   molecular_function
                                                                                                     molecular_function unknown unknown
 1      1   Ixodes pacificus
                       CLSP-8 IXODES PACIFICUS CLSP 8 CLSP-6 6 CLSP-7 70.00002 extrastructural molecule1activity 3 PUTATIVE SECRE
                                          Gly-Pro-Richs/Gly-Pro rich mucin like peptide with 5-CLSP-10 10 CLSP-1 CLSP-3 activity
                                                         collagen like
                                                                    structural molecule activity extracellular - structural molecule
                                                                                        CLSP-5        deomain post-mating behavior
 2      3              PUTATIVE RECEPTOR-LIKE KINASE ORYZA SATIVA JAPONICA CULTIVAR-GROUP RECEPTOR LIKE CULTIVAR GR
                                          3.2 kDa      s/Gly-Pro rich
            Oryza sativa (japonica cultivar-group) Gly rich peptide
 1      1   Ixodes pacificus
                       CLSP-11 IXODESProline rich peptide 11rich
                                           PACIFICUSs/Gly-Pro CLSP-2 2 CLSP-9 0.025
                                                         CLSP                              CLSP-1 1 CLSP-4 4 - transcription regulator activity - pos
                                                                                                     transcriptionWnt receptor signaling pathway
                                                                                                                    regulator activity
                                                                    nucleus - segment9polarity determination CLSP-3 3 PUTATIVE SECRETED SCA
 1      1              PUTATIVE SECRETED IXODES SCAPULARIS DANIO RERIO PE-PGRS FAMILY MYCOBACTERIUM TUBERCULOSIS
            Ixodes scapularis                          s/Gly-Pro embryonic development (sensu Animalia)
                                          Proline rich peptide rich                     0.096
48     35                                 Proline rich peptide rich
                                                       s/Gly-Pro collagen fibril organization - proteoglycan SMOOTH MUSCLE CELLS PEPTIDE 9
                                                                                       0.0002          CATTLE metabolism - cartilage condensation
                                                                                                                 structural molecule activity
                       COLLAGEN ALPHA 1 XI CHAIN CHICKEN FRAGMENT ALPHA-1 TYPEextracellular matrix structural constituent||structura
 1      1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP 1 CLSP-9 9 CLSP-3 3 CLSP-2 2 CLSP-11 11
                                          Gly-Pro-Richs/Gly-Pro rich mucin type peptide of matureprotein binding||binding
                                                         collagen like
                                                                    collagen like IV - 0.025          molecular weight ~ 4
                                                                                                                 binding
                                                                                        membrane - basement membrane kDa
158   32              PREDICTED SIMILAR TOrich peptide XB ISOFORM 1 CANIS FAMILIARIS PROBABLE D-AMINOPEPTIDASE MESORH
           Canis familiaris                      s/Gly-Pro
                                    Gly Pro TENASCIN rich
 1     1   Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP 1 CLSP-9 9 CLSP-3 3 CLSP-2 2 CLSP-11 11
                                    Gly-Pro-Richs/Gly-Pro rich mucin type peptide of matureprotein binding||binding
                                                  collagen like
                                                             collagen like IV - 0.025          molecular weight ~ 4
                                                                                                           binding
                                                                                 membrane - basement membrane kDa
 1     1   Ixodes pacificus
                      CLSP-2 IXODES PACIFICUS CLSP 2 CLSP-11 perception 0.0006maturestructural constituent molecule activity CLSP-3 3
                                    Gly-Pro-Richs/Gly-Pro rich mucin like peptide of
                                                  collagen like
                                                             visual 11 CLSP-9-9 CLSP-1 regulation of cell proliferation - organogenesis - colla
                                                                                               molecular SECRETED SCAPULARIS
                                                                                                           structural kDa
                                                                                  negative 1 PUTATIVE weight ~ 4of cuticle||structural molecul
 1     1              NPL-2
           Ixodes pacificus IXODES PACIFICUS NPL 2 PUTATIVE SECRETED1E-14 cytoskeleton - PEPTIDE SCAPULARIS NPL-1 1 FIBRILL
                                    Gly rich peptide
                                                 s/Gly-Pro rich
                                                             structural constituent of        structural constituent molecule - cytoskeleton - m
                                                                                                           structural of cytoskeleton||structural in
                                                                                  SALIVARY GLAND epidermis developmentactivity
 1     1              CLSP-9 IXODES PACIFICUS peptide CLSP-4 4 CLSP-2 2 CLSP-11 11 PUTATIVE SECRETED SCAPULARIS CLSP-7 7
           Ixodes pacificus                      s/Gly-Pro
                                    Proline rich CLSP 9 rich
 1     1              PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP 1 CLSP-9 9 CLSP-11 11 CLSP-2 2 CLSP-3 3
           Ixodes scapularis                      collagen like
                                    Gly-Pro-Richs/Gly-Pro rich mucin like peptide of mature molecular weight ~ 4 kDa
 1     1   Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS -CLSP 1 CLSP-3 3 CLSP-2 cuticle||structural molecul
                                    Gly-Pro-Richs/Gly-Pro rich mucin like peptide of maturestructural constituent molecule activity CLSP-9 9
                                                  collagen like
                                                             circulation - organogenesis collagen typeweight ~ 4of 2 CLSP-11 11
                                                                                 0.001                      III
                                                                                               molecular structural kDa
 1     1   Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS CLSP-2 PACIFICUS CLSP 2 CLSP-11 11 ~ 4 kDa 1 CLSP-9 9 CLSP-3 3
                                    Gly-Pro-Richs/Gly-Pro rich mucin like peptide of matureprotein-self weight CLSP-1 of body size - locomoto
                                                  collagen like
                                                             post-embryonic body morphogenesis positive regulation binding||binding
                                                                                 0.019                     binding||protein
                                                                                               molecular binding
 1     1   Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP 1 CLSP-2 2 CLSP-11 11 CLSP-9 9 CLSP-3 3
                                    Gly-Pro-Richs/Gly-Pro rich mucin like peptide of maturestructural constituent molecule activity
                                                  collagen like
                                                             locomotory behavior 0.004                     structural kDa
                                                                                               molecular weight ~ 4of cuticle||structural molecul
 1     1   Ixodes scapularis
                      PUTATIVE IXODES SCAPULARIS SECRETED CLSP-1 PACIFICUS CLSP (sensuconstituent molecule activity CLSP-9 9
                                    proline serine rich peptide
                                                 s/Gly-Pro rich
                                                             extracellular - cuticle biosynthesis 1 CLSP-3 3 CLSP-2 cuticle||structural molecul
                                                                                 0.001                     structural of 2 CLSP-11 11
                                                                                              structural Nematoda) - structural constituent of c
 1     1   Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP 1 CLSP-9 9 CLSP-2 2 CLSP-11 11 CLSP-3 3
                                    Gly-Pro-Richs/Gly-Pro rich mucin like peptide of matureprotein binding||binding
                                                  collagen like
                                                             protein binding 0.029             molecular weight ~ 4 kDa
                                                                                                           binding
 1     1   Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP 1 CLSP-3 3 CLSP-2 cuticle||structural locomoto
                                    proline serine rich peptide
                                                 s/Gly-Pro rich
                                                             post-embryonic body morphogenesis - positive regulationCLSP-8 8 CLSP-11 11
                                                                                 0.002                     structural of 2 of body size
                                                                                              structural constituent molecule activity - molecul
 1     1   Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP (sensuconstituent molecule activity CLSP-8 8
                                    proline serine rich peptide
                                                 s/Gly-Pro rich
                                                             extracellular - cuticle biosynthesis 1 CLSP-3 3 CLSP-2 cuticle||structural molecul
                                                                                 0.001                     structural of 2 CLSP-11 11
                                                                                              structural Nematoda) - structural constituent of c
 1     1   Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP 1 CLSP-3 3 CLSP-8 cuticle||structural locomoto
                                    proline serine rich peptide
                                                 s/Gly-Pro rich
                                                             post-embryonic body morphogenesis - positive regulationCLSP-2 2 CLSP-6 6 CL
                                                                                0.0005                     structural of 8 of body size
                                                                                              structural constituent molecule activity - molecul
 1     1   Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS CLSP 1 CLSP-3 3 CLSP-2 2 CLSP-11 11 CLSP-9 9
                                    Gly-Pro-Richs/Gly-Pro rich mucin like peptide of maturestructural molecule activity
                                                  collagen like
                                                             embryonic development (sensu molecular weight ~ 4molecule activity
                                                                                0.0001         Animalia) structural kDa
 1     1   Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS CLSP-2 PACIFICUS CLSP 2 CLSP-11 11 ~ 4molecule activity CLSP-3 3
                                    Gly-Pro-Richs/Gly-Pro rich mucin like peptide of maturestructural constituent of cuticle||structural locomoto
                                                  collagen like
                                                             post-embryonic body morphogenesis - positive regulation 9 CLSP-1 1 - molecul
                                                                                  0.01                     structural kDa
                                                                                               molecular weight CLSP-9 of body size
 1     1   Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS CLSP-1 PACIFICUS-CLSP 1 CLSP-3 3 CLSP-2 behavior 11 CLSP-9 9
                                    Gly-Pro-Richs/Gly-Pro rich mucin like peptide of maturestructural molecule activityCLSP-11
                                                  collagen like
                                                             structural molecule activity extracellular -weight ~ 4molecule activity
                                                                               0.00006                     post-mating 2
                                                                                               molecular structural kDa
 1     1   Ixodes scapularis
                      PUTATIVE SECRETED IXODES SCAPULARIS bindingpeptide of maturesugar binding||carbohydrate binding||binding and
                                    Gly-Pro-Richs/Gly-Pro rich mucin like - bacterial bindingmolecular weight ~ 4 kDa 2 CLSP-1 1 CLSP-8 8
                                                  collagen like
                                                             sugar CLSP-11 PACIFICUS CLSP 11 CLSP-9 cytokine production - oxygen
                                                                               0.00007                     binding
                                                                                                - regulation of 9 CLSP-2
 1     1              PUTATIVE SECRETED IXODES SCAPULARIS CLSP-9 PACIFICUS CLSP 9 CLSP-11 11 ~ 4 kDa 2 CLSP-1 1 CLSP-3 3
           Ixodes scapularis                      collagen like
                                    Gly-Pro-Richs/Gly-Pro rich mucin like peptide of mature molecular weight CLSP-2

14    12   Ixodes scapularis
                      PUTATIVE 18.7 KDA SECRETED IXODES SCAPULARIS 18.9inflammatory 19 CG6124-PA DROSOPHILA MELANOGAS
                                     putative 18.7s/18.7 kDa calcium ionfamily 0.085
                                                   kDa secreted protein binding - PACIFICUS response - adult heart ion binding||ionblood co
                                                             family                                       binding||metal development - binding
                                                                                             calcium ion binding
 1     1   Ixodes scapularis
                      PUTATIVE 18.7 KDA SECRETED IXODES SCAPULARIS 19glycosylation - lipidUNNAMED PRODUCT mediated endocyto
                                     putative 18.7s/18.7 kDa protein amino acid PACIFICUS 18.9 metabolismstructural constituent||structura
                                                   kDa secreted protein family 0.064
                                                             family                          extracellular matrix - molecule TETRAODON NIG
                                                                                                         structural receptor activity
 1     1   Ixodes scapularis
                      PUTATIVE 18.7 KDA SECRETED IXODES SCAPULARIS 19-PACIFICUS 18.9 SIMILAR TO MELLIFERA binding - low-de
                                     putative 18.7s/18.7 kDa extracellular space integral to protein binding||binding - protein DENSITY LIPO
                                                   kDa secreted protein family 0.037
                                                             family                          membrane binding
                                                                                                          - endosome
 1     1              PUTATIVE 18.7 KDA SECRETED IXODES SCAPULARIS 19 PACIFICUS 18.9domains MEMBER 27.5 KD CAENORHAB
           Ixodes scapularis                       kDa secreted protein family - has two repeated FAMILY
                                     putative 18.7s/18.7 kDa family
 2     1   Ixodes pacificus
                      PUTATIVE 19 KDA SECRETED IXODES low-density lipoprotein receptorlow-density signal transducer endocytosis - protein
                                     18.7 family s/18.7 kDa family
                                                             PACIFICUS 18.7 SCAPULARISactivity - receptor mediated activity
                                                                               0.017                      lipoprotein receptor activity||lipoprotein
                                                                                               18.9 PROTEOLIAISIN LYTECHINUS VARIEGA
 1     1              PUTATIVE 18.7 KDA SECRETED IXODES SCAPULARIS 19 PACIFICUS 18.9 IMMUNOGLOBULIN HEAVY CHAIN HOM
           Ixodes scapularis                       kDa secreted protein
                                     putative 18.7s/18.7 kDa family

 1     1              PUTATIVE SECRETED PEPTIDE 6.3 KDA IXODES PACIFICUS 4.99 ANOPHELES GAMBIAE STR. PEST HYPOTHETIC
           Ixodes pacificus                        collagen like mucin like peptide of mature molecular weight ~ 4 kDa
                                     Gly-Pro-Richs/5
 1     1              PUTATIVE SECRETED PEPTIDE 4.99 KDAneurotoxinPACIFICUS 6.3 4.3 GIARDIA INTESTINALIS ORF-C4 ORF C4 LAM
           Ixodes pacificus                       s/5
                                     weakly similar to paralytic IXODES
486   27   Candida glabrata
                      UNNAMED PRODUCT CANDIDA GLABRATA4.2 kDa SACCHAROMYCES CEREVISIAE - postreplication repair - nucleot
                                     putative secreted peptide of RFA1P
                                                  s/5                           0.017        single-stranded DNA REPLICATION FACTOR-
                                                                                                         repair 4312
                                                              DNA recombination - double-strand break binding binding||DNA binding||nuclei
36    37              PUTATIVE SECRETED PEPTIDE 4.99 KDA IXODES PACIFICUS PREDICTED SIMILAR TO TESTIS EXPRESSED SEQ
           Ixodes pacificus                       s/5
                                     holocyclotoxin-6
 1     1              PUTATIVE SECRETED PEPTIDE 4.99 KDA IXODES PACIFICUS 5.3 SCAPULARIS 6.3 4.3 SAPIENS RIKEN CDNA MU
           Ixodes pacificus                       s/5.3
                                     4.8 kDa peptide family
 1     1              PUTATIVE SECRETED PEPTIDE 4.99 KDA IXODES PACIFICUS 6.3 4.3 NEUROTOXIN TX2-6 PHONEUTRIA NIGRIVEN
           Ixodes pacificus                       s/5.3
                                     4.7 kDa peptide family
 1     1              PUTATIVE SECRETED PEPTIDE 4.99 KDA IXODES PACIFICUS 6.3 5.3 SCAPULARIS ISOFORM D DROSOPHILA MEL
           Ixodes pacificus                       s/5.3
                                     4.6 kDa peptide family
 1     1              PUTATIVE 5.3 KDAkDa peptide/5.3 family SCAPULARIS PEPTIDE 4.3 PACIFICUS 4.99 6.3 SIMILAR TO PRECURSOR
           Ixodes scapularis                      s
                                     5 SECRETED IXODES
 1     1              PUTATIVE 5.3 KDAkDa peptide/5.3 family SCAPULARIS PEPTIDE 4.3 PACIFICUS 4.99 ISOFORM B DROSOPHILA MEL
           Ixodes scapularis                      s
                                     5 SECRETED IXODES
 4     1              PUTATIVE SECRETED PEPTIDE 4.3 KDAfamily
           Ixodes pacificus                       s/5.3 family
                                     putative 5.3 kDa peptide IXODES PACIFICUS 5.3 SCAPULARIS UNNAMED PRODUCT TETRAODON
 1     1              PUTATIVE 5.3 KDA SECRETED IXODES SCAPULARIS PEPTIDE 4.3 PACIFICUS 4.99 6.3 DROSOPHILA MELANOGAS
           Ixodes scapularis                      s/5.3 family
                                     putative 5.0 kDa secreted peptide
 1     1              PUTATIVE 5.3 KDA SECRETED IXODES SCAPULARIS PEPTIDE 4.3 PACIFICUS ISOFORM B DROSOPHILA MELANO
           Ixodes scapularis                      s/5.3 family
                                     putative 5.3 kDa peptide family
 1     1              PUTATIVE 5.3 KDA SECRETED IXODES SCAPULARIS PEPTIDE 4.3 PACIFICUS 4.99 PREDICTED SIMILAR TO INOS
           Ixodes scapularis                      s/5.3 family
                                     putative 5.3 kDa peptide family
 1     1              PUTATIVE 5.3 KDA SECRETED IXODES SCAPULARIS PEPTIDE 4.3 PACIFICUS PREDICTED SIMILAR TO TESK2 GA
           Ixodes scapularis                      s/5.3 family
                                     putative 5.3 kDa peptide family
 8     1              PUTATIVE SECRETED PEPTIDE 4.3 KDA IXODES PACIFICUS 5.3 SCAPULARIS 4.99 6.3 NOTCH RECEPTOR DANIO
           Ixodes pacificus                       s/5.3 family
                                     putative 5.3 kDa secreted peptide
 8     1   Ixodes pacificus
                      PUTATIVE SECRETED PEPTIDE 4.3 KDAfamily
                                     putative 5.3 kDa peptide IXODES PACIFICUSfactor activity -binding||receptor binding||signal TO-VERTE
                                                  s/5.3 familyNotch binding - growth 5.3 SCAPULARIS signal transducer SIMILAR transducer
                                                                                0.096        Notch cell fate determination - cell cycle Notch
                                                                                                         4.99 6.3 NOVEL activity
 8     1              PUTATIVE SECRETED PEPTIDE 4.3 KDAfamily
           Ixodes pacificus                       s/5.3 family
                                     putative 5.3 kDa peptide IXODES PACIFICUS 5.3 SCAPULARIS 4.99 6.3 NOTCH RECEPTOR DANIO

1     1               PUTATIVE SECRETED SALIVARY peptide
           Ixodes pacificus                       s/7-9
                                     6.7 kDa secreted PEPTIDE 6.78 KDA IXODES PACIFICUS 7 SCAPULARIS 9.41 GLAND 8.9 9.4 9.57
1     1               PUTATIVE SECRETED SALIVARY peptide PEPTIDE IXODES SCAPULARIS 8.9 KDA 9.4 9.41 PACIFICUS TXLP1 BUTH
           Ixodes scapularis                      s/7-9
                                     10.8 kDa salivary GLAND
1     1               PUTATIVE SECRETED salivary peptide
           Ixodes pacificus                       s/7-9
                                     7 kDa SALIVARY PEPTIDE 6.78 KDA IXODES PACIFICUS 7 SCAPULARIS 9.41 9.57 GLAND 9.4 8.9
1     1               PUTATIVE 9.4 KDA SECRETED IXODES SCAPULARIS SALIVARY PEPTIDE 9.41 PACIFICUS 9.57 GLAND DROSOPH
           Ixodes scapularis                      s/7-9
                                     9.3 kDa secreted peptide - similar to rat stem cell derived neuronal survival protein
1     1               PUTATIVE 9.4 KDA SECRETED IXODES SCAPULARIS SALIVARY PEPTIDE 9.41 PACIFICUS 9.57 GLAND 8.9 7 6.78 B
           Ixodes scapularis                      s/7-9
                                     9.3 kDa secreted peptide - similar to rat stem cell derived neuronal survival protein
1     1               PUTATIVE 7 KDAputative 7 kDa secreted protein
           Ixodes scapularis                      s/7-9
                                      SECRETED IXODES SCAPULARIS SALIVARY PEPTIDE 6.78 PACIFICUS 9.41 9.57 GLAND DROSO
1     1               PUTATIVE SECRETED SALIVARY PEPTIDE 9.41 KDA IXODES PACIFICUS 9.4 SCAPULARIS 9.57 GLAND 6.78 7 8.9 P
           Ixodes pacificus                       s/7-9
                                     putative 9.4 kDa secreted protein
1     1               PUTATIVE SECRETED SALIVARY peptide
           Ixodes pacificus                       s/7-9
                                     6.7 kDa secreted PEPTIDE 6.78 KDA IXODES PACIFICUS 7 SCAPULARIS 9.41 9.57 9.4 GLAND 8.9 K
7     7               PUTATIVE SECRETED peptide/7-9 GLAND PEPTIDE IXODES SCAPULARIS 8.9 KDA 9.4 TXLP1 BUTHUS MARTENSII
           Ixodes scapularis                      s
                                     9 kDa SALIVARY
7     7               PUTATIVE SECRETED peptide similar to scorpion toxin
           Ixodes scapularis                      s/7-9
                                     9 kDa SALIVARY GLAND PEPTIDE IXODES SCAPULARIS 8.9 KDA 9.4 TXLP1 BUTHUS MARTENSII
1     1               PUTATIVE SECRETED SALIVARYcomplement membrane cofactor protein
           Ixodes scapularis                      s/scorp
                                     weakly similar to GLAND PEPTIDE IXODES SCAPULARIS 8.9 KDA 9.4 9.41 PACIFICUS TXLP1 BUTH
1     1               PUTATIVE 9.4 KDA SECRETED IXODES SCAPULARIS SALIVARY PEPTIDE 9.41 PACIFICUS 9.57 GLAND DROSOPH
           Ixodes scapularis                      s/7-9
                                     putative secreted salivary peptide of 9.3 kDa
1     1               PUTATIVE 7 KDAputative secreted salivary peptide of 7SALIVARY PEPTIDE 6.78 PACIFICUS 9.41 8.9 9.57 GLAND DRO
           Ixodes scapularis                      s/7-9
                                      SECRETED IXODES SCAPULARIS kDa

1     1    Ixodes scapularis
                      TRUNCATED SECRETED METALLOPROTEASEbinding 0.0000003 regulation ofbinding||receptor binding||signal transduce
                                   Disintegrin metalloproteinases with thrombospondin repeats
                                                s/enz metaloprotease
                                                           integrin IXODESnegative        integrin cell adhesion - integral to membrane
                                                                                                      signal transducer activity
                                                                           - SCAPULARIS SALIVARY GLAND HYPOTHETICAL RICINUS
1     1    Ixodes scapularis
                      SALIVARY GLAND METALLOPROTEASE IXODES SCAPULARIS HYPOTHETICAL RICINUS TRUNCATED SECRETED
                                   Disintegrin metalloproteinases with1 space - protein prenyltransferase activity - protein amino acid preny
                                                s/enz metaloprotease thrombospondin repeats prenyltransferase activity||prenyltransferas
                                                           extracellular 0.00000003       protein     catalytic activity
1     1    Ixodes scapularis
                      SALIVARY GLAND METALLOPROTEASE IXODES SCAPULARIS HYPOTHETICAL RICINUS TRUNCATED SECRETED
                                   Disintegrin metalloproteinases with1 space - protein prenyltransferase activity - protein amino acid preny
                                                s/enz metaloprotease thrombospondin repeats prenyltransferase activity||prenyltransferas
                                                           extracellular 0.00000003       protein     catalytic activity
1     1    Ixodes scapularis
                      TRUNCATED SECRETED fertilins and related Zn-dependent metalloproteinases of the ADAMs family SALIVARY PACIFI
                                  Meltrins, METALLOPROTEASE IXODES activity
                                              s/enz metaloprotease 1 0.000000005
                                                          metallopeptidase SCAPULARIS HYPOTHETICAL RICINUS
                                                                                                   catalytic activity
                                                                                       metallopeptidase activity||peptidase activity||hydro

 1     1              PUTATIVE SALIVARY SECRETED PEPTIDE IXODES PACIFICUS
           Ixodes pacificus                     s/RGD
                                    4.1 kDa peptide
 1     1              PUTATIVE SALIVARY SECRETED PEPTIDE IXODES PACIFICUS UNNAMED PRODUCT TETRAODON NIGROVIRIDIS
           Ixodes pacificus                     s/RGD
                                    4.1 kDa peptide with RDG motif
 1     1              PUTATIVE SALIVARY SECRETED PEPTIDE IXODES PACIFICUS SIMILAR TO C-SERATE-1 APIS MELLIFERA C SER
           Ixodes pacificus                     s/RGD
                                    4.2 kDa peptide
105   31   Gekko japonicus
                      GEKBS205P GEKKO JAPONICUS PUTATIVE SALIVARY0.00006
                                    9 kDa peptide/RGD
                                                s                            SECRETED PEPTIDE IXODES PACIFICUS GLAND SCAPUL
                                                                                             enzyme      enzyme regulator activity
                                                           regulation of protein activity, epigenetic activator activity||enzyme regulator activit


104   29   Gekko japonicus
                     GEKBS205P GEKKO family member - venom and hormone-like
                                  IS6 JAPONICUS PUTATIVE SALIVARY SECRETED PEPTIDE IXODEStransducer activity
                                             s/IS6                         0.005        integrin binding||receptor binding||signal SCAPUL
                                                       extracellular - extracellular space          signal PACIFICUS GLAND transduce



147    9   Mus musculus              8.7 kDa peptide weakly skeletal development endothelial regulator precursor HOMEOTIC HOX 4.7 MO
                                                  s/ixostatin-stabilin to BMP-binding
                                                               similar            0.016
                       HOMEO BOX D12 MUS MUSCULUS HXDC_MOUSE HOMEOBOX HOX-D12 HOX-4.7 HOX-5.6protein
 1     1               SALIVARY GLAND AkDa protein
           Ixodes scapularis                       SCAPULARIS PUTATIVE SECRETED PEPTIDE 9.1 KDA PACIFICUS DROSOPHILA ME
                                     12 IXODESs/ixostatin family
21     1               SALIVARY GLAND AkDa peptide
           Ixodes scapularis                       SCAPULARIS PUTATIVE SECRETED PEPTIDE 9.1 KDA PACIFICUS SAPIENS AGRIN H
                                     10 IXODESs/ixostatin family
 1     1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES motif peptide PACIFICUS THROMBOSPONDIN ANOPHELES GAMBIAE activity||hydro
                                     ADAM cys-rich SCAPULARIS
                                                  s/ixostatin extracellular space 0.003                    catalytic activity
                                                                                               metallopeptidase activity||peptidase STR. PEST P
 1     1               SALIVARY GLAND AkDa protein
           Ixodes scapularis                       SCAPULARIS PUTATIVE SECRETED PEPTIDE HYPOTHETICAL CAENORHABDITIS EL
                                     11 IXODESs/ixostatin family
271    9   Homo sapiens              8.1 kDa peptide Kunitz family
                                                  s/ixostatin CAENORHABDITIS ELEGANS NA24_CAEEL METALLOPROTEINASE NAS-24
                       SIMILAR TO SAPIENS HYPOTHETICALMetalCys
 1     1               SALIVARY GLAND AkDa protein
           Ixodes scapularis                       SCAPULARIS
                                     11 IXODESs/16kda family PUTATIVE SECRETED PEPTIDE 9.1 KDA PACIFICUS DROSOPHILA ME
 1     1               SALIVARY GLAND A kDa peptide
           Ixodes scapularis                       SCAPULARIS
                                     9.2 IXODESs/9.2
 7     1               SALIVARY GLAND IXODES SCAPULARIS PUTATIVE PEPTIDE 11.9 KDA PACIFICUS SECRETED 11.3 14.4 16 KD FO
           Ixodes scapularis                      s/ixostatin PCGP
                                     12 kDa protein
 1     1   Ixodes scapularis
                       THROMBOSPONDIN IXODESs/ixostatin fertilization (sensu0.058
                                     thrombonspondin family
                                                   SCAPULARIS PUTATIVE SECRETED - metallopeptidase activity
                                                                                               metallopeptidase activity||peptidase activity||hydro
                                                                                                           catalytic activity
                                                                                   Animalia) PACIFICUS HYPOTHETICAL CAENORHABDITIS
 1     1               THROMBOSPONDIN IXODESs/ixostatin thrombospondin SECRETED PACIFICUS SALIVARY GLAND PEPTIDE 11.3 KD
           Ixodes scapularis                       SCAPULARIS PUTATIVE
                                     thrombonspondin family
 1     1   Ixodes pacificus
                       IXODES PACIFICUS PUTATIVE SECRETED SCAPULARIS0.02
                                     tick thrombospondin family
                                                  s/ixostatin extracellular space - protein prenyltransferase activity - protein SALIVARY GLAN
                                                                                               protein prenyltransferase KDA amino acid preny
                                                                                                           catalytic activity
                                                                                    THROMBOSPONDIN PEPTIDE 11.3activity||prenyltransferas
 1     1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS PACIFICUS THROMBOSPONDIN TRUNCATED development (sensu NeS
                                     tick thrombospondin family
                                                  s/ixostatin osmoregulation - positive regulation of prenyltransferase activity||prenyltransferas
                                                                                  0.007                    catalytic activity
                                                                                               protein body size - larval METALLOPROTEASE
 7     1               SALIVARY GLAND IXODES SCAPULARIS PUTATIVE PEPTIDE 11.9 KDA PACIFICUS 16 KD TEGUMENT HUMAN HER
           Ixodes scapularis                      s/ixostatin PCGP
                                     13 kDa peptide
 1     1   Ixodes pacificus
                       IXODES PACIFICUS PUTATIVE SECRETED SCAPULARIS - protein prenyltransferase activity - protein amino acid preny
                                     ADAM cys-rich motif peptide
                                                  s/ixostatin extracellular space THROMBOSPONDIN HYPOTHETICAL CAENORHABDITIS
                                                                                  0.056                    catalytic activity
                                                                                               protein prenyltransferase activity||prenyltransferas
21     1               SALIVARY GLAND AkDa peptide
           Ixodes scapularis                       SCAPULARIS PREDICTED SIMILAR TO DISINTEGRIN-LIKE METALLOPROTEASE REP
                                     10 IXODESs/ixostatin family
 1     1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES motif peptide PACIFICUS THROMBOSPONDIN SALIVARY GLAND PEPTIDE TRUNC
                                     ADAM cys-rich SCAPULARIS
                                                  s/ixostatin osmoregulation - positive regulation of prenyltransferase development (sensu Ne
                                                                                  0.002                    catalytic activity
                                                                                               protein body size - larval activity||prenyltransferas
25    28               PUTATIVE SECRETED IXODES SCAPULARIS PEPTIDE 11.3 KDA PACIFICUS SIMILAR TO ADAM32 RATTUS NORVE
           Ixodes scapularis                      s/Ixostatin ACR
                                     similar to cys rich domain of ADAM
322   11   Yarrowia lipolytica
                       UNNAMED PRODUCT YARROWIA LIPOLYTICAbinding - HYPOTHETICAL MDC15binding adhesion - integral to membra
                                     ADAM cys-rich motif peptidedomain 15 SH3 domain binding -binding||binding
                                                  s/ixostatin ACR
                                                               protein CLIB99 0.034            protein cell-matrix
                                                                                                            DISINTEGRIN-LIKE METALLOPROT
 1     1               SALIVARY GLAND AkDa protein
           Ixodes scapularis                       SCAPULARIS PUTATIVE frame
                                     11 IXODESs/ixostatin sco-ponding cys SECRETED JUVENILE HORMONE EPOXIDE HYDROLASE AE
 6     1               SALIVARY GLAND AkDa protein
           Ixodes scapularis                       SCAPULARIS PUTATIVE PEPTIDE 9.1 KDA PACIFICUS SECRETED PREDICTED SIMIL
                                     12 IXODESs/ixostatin family
 9     4   Mus musculus              13 kDa peptide Kunitz family
                                                  s/ixostatin MetalCys
                       MUSCULUS RIKEN CDNA Q9CQB7 YG01_MOUSE FAMILY HOMOLOG UNNAMED PRODUCT AFL046WP ASHBYA G
 1     1               SALIVARY GLAND AkDa peptide
           Ixodes scapularis                       SCAPULARIS
                                     10 IXODESs/16kda family PUTATIVE PEPTIDE 9.1 KDA PACIFICUS SECRETED DROSOPHILA ME
 1     1               PUTATIVE SECRETED SALIVARY GLAND PEPTIDE space - integral to membrane FERTILIN BETA SUBUNIT PH 30 U
           Ixodes scapularis                      s/ixostatin ACR
                                                               extracellular IXODES SCAPULARIS PH-30
                                     ADAM cys-rich motif peptide                  0.005
 1     1               PUTATIVE SECRETED SALIVARY GLAND PEPTIDE space - integral to membrane
           Ixodes scapularis                      s/ixostatin ACR
                                                               extracellular IXODES SCAPULARIS PACIFICUS FERREDOXIN ACTINOBACIL
                                     ADAM cys-rich motif peptide                  0.034
 7     1   Ixodes scapularis
                       SALIVARY GLAND IXODES SCAPULARIS PUTATIVE PEPTIDE 11.9 KDA PACIFICUS SECRETED activity SIMILAR
                                     11 kDa peptide
                                                  s/ixostatin PCGP transducer activity - phagocytosis, engulfment - apoptosis 11.3
                                                               signal             0.057        signal transducer activity
                                                                                                           signal transducer 14.4
93    12               HYPOTHETICAL CAENORHABDITIS ELEGANS PREDICTED CDS PUTATIVE 3D75 HELICOBACTER PYLORI SCO-SP
           Caenorhabditis elegans                 s/ixostatin sco-ponding to SCO-Spondin/Thrombospondin
                                     9.7 kDa peptide with weak similarity cys frame
30    44               PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS TRUNCATED METALLOPROTEASE PACI
           Ixodes scapularis                       peptide
                                     11.6 salivarys/ixostatin family
 5     1   Ixodes scapularis
                       PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS ofbinding||receptor binding||signal transduce
                                     tick thrombosponding family hasbinding - negative regulation THROMBOSPONDIN PACIFICUS UNNAM
                                                  s/ixostatin integrin thioredoxin motif
                                                                                  0.044        integrin cell adhesion - integral to membrane
                                                                                                           signal transducer activity
26    30   Ixodes scapularis
                       PUTATIVE SECRETED IXODES motif peptide PACIFICUS FERTILINconstituent - structural molecule PRECURSOR A D
                                     ADAM cys-rich SCAPULARIS
                                                  s/Ixostatin ACR
                                                               extracellular matrix structural BETA SUBUNIT AD02_RABIT activity developm
                                                                                  0.096                    calcium ion binding - skeletal
                                                                                               extracellular matrix structural constituent||structura
 1     1               PUTATIVE SECRETED SALIVARY family PEPTIDE IXODES SCAPULARIS THROMBOSPONDIN 11.3 KDA PACIFICU
           Ixodes scapularis                      s/ixostatin
                                     thrombonspondin GLAND
 1     1               PUTATIVE SECRETED SALIVARY family PEPTIDE IXODES SCAPULARIS 9.1 KDA PACIFICUS A THROMBOSPOND
           Ixodes scapularis                      s/ixostatin
                                     thrombonspondin GLAND
 1     1               PUTATIVE SECRETED SALIVARY peptide of11.5 kDa IXODES SCAPULARIS 11.3 KDA PACIFICUS DP87_DICDI PRES
           Ixodes scapularis                      s/ixostatin PCGP
                                     putative secreted GLAND PEPTIDE
 1     1               PUTATIVE SECRETED IXODES SCAPULARIS PACIFICUS - integral to integrin binding||receptor binding||signal transduce
           Ixodes scapularis                      s/ixostatin                    0.0008         membrane signal transducer activity
                                     thrombonspondin familyextracellular space THROMBOSPONDIN ANOPHELES GAMBIAE STR. PEST S
 1     1   Ixodes scapularis
                       PUTATIVE SECRETED IXODES SCAPULARIS PACIFICUS THROMBOSPONDIN PEPTIDE 11.3development (sensu Ne
                                     thrombonspondin familyosmoregulation - positive regulation of prenyltransferase activity||prenyltransferas
                                                  s/ixostatin                     0.004        protein body size - larval KDA HYPOTHETICAL
                                                                                                           catalytic activity
 1     1               SALIVARY GLAND AkDa salivary gland protein A
           Ixodes scapularis                       SCAPULARIS PUTATIVE PEPTIDE 9.1 KDA PACIFICUSregulation of body size - positive
                                                               post-embryonic body morphogenesis - positive SECRETED HYPOTHETICAL C
                                     16 IXODESs/ixostatin family                  0.053
 1     1               SALIVARY GLAND IXODES SCAPULARIS PUTATIVE PEPTIDE 11.9 KDA PACIFICUS SECRETED 11.3 14.4 16 KD SIM
           Ixodes scapularis                      s/ixostatin PCGP
                                     15 kDa salivary gland protein
 1     1               THROMBOSPONDIN IXODESs/ixostatin osmoregulation - positive regulation of body size - larval development (sensu Ne
           Ixodes scapularis                       SCAPULARIS PUTATIVE SECRETED PACIFICUS SALIVARY GLAND PEPTIDE HYPOT
                                     thrombonspondin family                       0.033

 1     1                PUTATIVE 22.5 KDA SECRETED IXODES SCAPULARIS TSGP4 ORNITHODOROS SAVIGNYI LIPOCALIN-LIKE BOOP
           Ixodes scapularis           HBP 18.3 s/hbp21.9
 1     5                MALE-SPECIFIC HISTAMINE-BINDING SALIVARY RHIPICEPHALUS APPENDICULATUS HBPM_RHIAP PRECURSOR
           Rhipicephalus appendiculatusHBP 19     s/hbp19
 1     1                SALIVARY GLAND B IXODESs/hbp26
           Ixodes scapularis           HBP 23      SCAPULARIS LIPOCALIN-LIKE BOOPHILUS MICROPLUS LIPOCALIN LIKE PUTATIVE
36    48                LIPOCALIN-LIKE BOOPHILUS MICROPLUS LIPOCALIN LIKE PUTATIVE SECRETED HISTAMINE BINDING 22.8 KDA I
           Boophilus microplus         HBP 21.8 s/hbp/21.8
36    41                LIPOCALIN-LIKE BOOPHILUS MICROPLUS LIPOCALIN LIKE PUTATIVE SECRETED HISTAMINE BINDING 22.8 KDA I
           Boophilus microplus         HBP 23.8 s/hbp23.8
 1     1                PUTATIVE IXODES SCAPULARIS SALIVARY GLAND A B SECRETED HISTAMINE BINDING 22.5 KDA PACIFICUS 25.
           Ixodes scapularis           HBP 22     s/hbp23.1
 2    92                DEHYDROGENASE VIBRIO VULNIFICUS PUTATIVE CATION-EFFLUX TRANSPORTER COMPONENT MYCOBACTER
           Vibrio vulnificus YJ016     HBP 18.9 s/hbp18.9
 1     1                SALIVARY GLAND A IXODESs/hbp23.1
           Ixodes scapularis           HBP 23      SCAPULARIS PUTATIVE SECRETED HISTAMINE BINDING 22.5 KDA PACIFICUS 25.9
 1     1                HISTAMINE BINDING IXODES SCAPULARIS PUTATIVE SALIVARY GLAND B A SECRETED 22.5 KDA PACIFICUS 25.
           Ixodes scapularis           HBP 24     s/hbp23.1
 1     1                HISTAMINE BINDING IXODES SCAPULARIS PUTATIVE SALIVARY GLAND B A SECRETED 22.5 KDA PACIFICUS 25.
           Ixodes scapularis           HBP 24.4 s/hbp23.1
 1     1                HISTAMINE BINDING IXODES SCAPULARIS PUTATIVE SALIVARY GLAND B A SECRETED 22.5 KDA PACIFICUS 25.
           Ixodes scapularis           HBP 23     s/hbp23.1
 2    44                TRUNCATED HISTAMINE BINDING IXODES PACIFICUS TRYPSIN INHIBITOR SUBTYPE A GLYCINE MAX KUNITZ PR
           Ixodes pacificus                       s/hbp
                                       HBP truncated
 1    1               PUTATIVE 22.7 KDA SECRETED IXODES SCAPULARIS HISTAMINE BINDING 19.7 PACIFICUS SALIVARY GLAND A
           Ixodes scapularis           HBP 22.4 s/hbp23
 1    1               SALIVARY GLAND B IXODESs/hbp26
           Ixodes scapularis           HBP 25.6      SCAPULARIS PUTATIVE SECRETED PEPTIDE UNKNOWN FOR IMAGE DANIO RERIO
 1    1               SALIVARY GLAND B IXODESs/hbp26
           Ixodes scapularis           HBP20.7       SCAPULARIS PUTATIVE SECRETED PEPTIDE LIPOCALIN-LIKE BOOPHILUS MICROP
36   41               LIPOCALIN-LIKE BOOPHILUS MICROPLUS LIPOCALIN LIKE PUTATIVE SECRETED HISTAMINE BINDING 22.8 KDA I
           Boophilus microplus         HBP 23.9 s/hbp23.8
 1    1               PUTATIVE 22.5 KDA SECRETED IXODES SCAPULARIS TRUNCATED HISTAMINE BINDING PACIFICUS LIPOCALIN-L
           Ixodes scapularis           HBP 21.94 s/hbp21.9
29   31               PUTATIVE SECRETED HISTAMINE BINDING 20.0 KDA IXODES PACIFICUS MALE-SPECIFIC HISTAMINE-BINDING S
           Ixodes pacificus            HBP 18.7 s/hbp18.7
 1    1               SALIVARY GLAND B IXODESs/hbp26
           Ixodes scapularis           HBP 23.3      SCAPULARIS PUTATIVE SECRETED PEPTIDE SEROTONIN HISTAMINE BINDING DER
 1    1               SALIVARY GLAND B IXODESs/hbp26
           Ixodes scapularis           HBP 20.6      SCAPULARIS PUTATIVE SECRETED PEPTIDE HISTAMINE BINDING 22.8 KDA PACIFI
 3   41               TRUNCATED HISTAMINE BINDING IXODES PACIFICUS SCAPULARIS PUTATIVE SALIVARY GLAND A B SECRETED
           Ixodes pacificus            HBP 20       s/hbp20
 1    1               SALIVARY GLAND B IXODESs/hbp22
           Ixodes scapularis           HBP 22        SCAPULARIS PUTATIVE SECRETED PEPTIDE LIPOCALIN-LIKE BOOPHILUS MICROP
 1    1               PUTATIVE 22.5 KDA SECRETED IXODES SCAPULARIS TRUNCATED HISTAMINE BINDING PACIFICUS LIPOCALIN-L
           Ixodes scapularis           HBP 21.9 s/hbp21.9
 1    1               PUTATIVE 19 KDA SECRETED IXODES family
           Ixodes pacificus            18_3 family s/18.7 kDa PACIFICUS 18.9 18.7 SCAPULARIS BTSP-11 BTSP 11 LIPOPROTEIN RECEP
 1    1               SALIVARY GLAND B IXODESs/hbp21
           Ixodes scapularis           HBP 21        SCAPULARIS PUTATIVE SECRETED PEPTIDE LIPOCALIN-LIKE BOOPHILUS MICROP
 1    1               PUTATIVE 22.7 KDA SECRETED IXODES SCAPULARIS HISTAMINE BINDING 19.7 PACIFICUS 22.5 ORYZA SATIVA
           Ixodes scapularis                        s/hbp22.7
                                       putative secreted histamine binding protein of 23 kDa
 1    1               PUTATIVE 22.7 KDA SECRETED IXODES SCAPULARIS HISTAMINE BINDING 19.7 PACIFICUS 22.5 UNNAMED PROD
           Ixodes scapularis           HBP 23       s/hbp22.7
 1    1               PUTATIVE IXODES SCAPULARIS SALIVARY GLAND A B SECRETED HISTAMINE BINDING 22.5 KDA PACIFICUS 25.
           Ixodes scapularis                        s/hbp23
                                       histamine binding protein
 1    1               PUTATIVE 19 KDA SECRETED IXODES family
           Ixodes pacificus                          kDa secreted protein
                                       putative 18.7s/18.7 kDa PACIFICUS 18.7 SCAPULARIS 18.9 PREDICTED SIMILAR TO FERM RHOGE
 1    1               HISTAMINE BINDING IXODES SCAPULARIS SALIVARY GLAND B PUTATIVE A SECRETED 22.5 KDA PACIFICUS 25.
           Ixodes scapularis           HBP 24       s/hbp23.1
46   31               PUTATIVE SECRETED IXODES SCAPULARIS HISTAMINE BINDING 20.0 KDA PACIFICUS POLYMERASE ALPHA CA
           Ixodes scapularis           HBP 20.3 s/hbp20.3
 1    1               PUTATIVE SECRETED IXODES SCAPULARIS HISTAMINE BINDING 20.0 KDA PACIFICUS ARGINYL-TRNA SYNTHET
           Ixodes scapularis           HBP 21       s/hbp21
 1    1               PUTATIVE IXODES SCAPULARIS SALIVARY GLAND A B SECRETED HISTAMINE BINDING 22.5 KDA PACIFICUS 25.
           Ixodes scapularis           HBP 22       s/hbp23.1
 1    1               PUTATIVE 22.7 KDA SECRETED IXODES SCAPULARIS HISTAMINE BINDING 19.7 PACIFICUS HYPOTHETICAL MEM
           Ixodes scapularis           HBP 21.8 s/hbp23
 1    5               MALE-SPECIFIC HISTAMINE-BINDING SALIVARY RHIPICEPHALUS APPENDICULATUS HBPM_RHIAP PRECURSOR
           Rhipicephalus appendiculatusHBP 19       s/hbp19
 4   42               TRUNCATED HISTAMINE BINDING IXODES PACIFICUS SCAPULARIS SALIVARY GLAND A PUTATIVE B SECRETED
           Ixodes pacificus            HBP 19.8 s/hbp20
 3    5               PUTATIVE SECRETED HISTAMINE BINDING 20.0 KDA IXODES PACIFICUS LIPOCALIN-LIKE BOOPHILUS MICROPL
           Ixodes pacificus            HBP 20       s/hbp20
40   31               LIPOCALIN-LIKE BOOPHILUS MICROPLUS LIPOCALIN LIKE PUTATIVE SECRETED HISTAMINE BINDING 20.0 KDA I
           Boophilus microplus         HBP 21       s/hbp21
94   74               SIMILAR          HBP 17.6 s/hbp18
           Rattus norvegicus TO IMMUNOGLOBULIN SUPERFAMILY MEMBER 9 NCAM-LIKE NRT1 NEURAL CELL ADHESION MOLECUL
16   16               PUTATIVE SECRETED HISTAMINE BINDING 20.0 KDA IXODES activity - protein binding - general RNA polymerase II tra
           Ixodes pacificus                                                      0.064       transcription coactivator activity||transcription cofa
                                                                                                         transcription BOOPHILUS MICROPL
                                       HBP 20.1 s/HBP20.1 transcription coactivator PACIFICUS LIPOCALIN-LIKEregulator activity
 1    1               PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS TRANSPORTER ATP BINDING LACTOBA
           Ixodes scapularis           HBP 18       s/hbp18
 1    1    Ixodes scapularis
                      PUTATIVE SECRETED SALIVARY protein PEPTIDE matrix structural constituent - structural molecule unknownPACIFICU
                                       histamine binding GLAND
                                                    s/hbp24                      0.063       extracellular matrix structural constituent||structura
                                                                                                         biological_process activity
                                                               extracellular IXODES SCAPULARIS HISTAMINE BINDING 22.8 KDA - integral
 1    1               PUTATIVE 22.7 KDA SECRETED IXODES SCAPULARIS peripheral nervous system development 22.5 ISOFORM B DRO
           Ixodes scapularis                        s/hbp23    axon guidance - HISTAMINE BINDING 19.7 PACIFICUS
                                       weakly similar to holocyclotoxin          0.002
 1    1               PUTATIVE 22.5 KDA SECRETED IXODES SCAPULARIS TRUNCATED HISTAMINE BINDING PACIFICUS LIPOCALIN-L
           Ixodes scapularis                        s/hbp21.9
                                       histamine binding protein
 1    1               PUTATIVE SECRETED IXODES SCAPULARIS HISTAMINE BINDING 20.0 KDA PACIFICUS GUANYLATE KINASE STA
           Ixodes scapularis                        s/hbp23
                                       histamine binding protein
 1    1               PUTATIVE IXODES SCAPULARIS SALIVARY GLAND A B SECRETED HISTAMINE BINDING 22.5 KDA PACIFICUS 25.
           Ixodes scapularis                        s/hbp23
                                       putative secreted histamine binding protein of 23 kDa
 1    1               PUTATIVE SECRETED HISTAMINE BINDING IXODES SCAPULARIS TRUNCATED PACIFICUS 33.2 KDA 19.5 FEMALE
           Ixodes scapularis                        s/hbp34
                                       putative secreted histamine binding protein
 1    1               PUTATIVE SECRETED HISTAMINE BINDING IXODES SCAPULARIS 33.2 KDA PACIFICUS 19.5 TRUNCATED REPLIC
           Ixodes scapularis                        s/hbp33
                                       putative secreted histamine binding protein
 1    1               SALIVARY GLAND A IXODESs/hbp23
           Ixodes scapularis                         SCAPULARIS
                                       histamine binding protein PUTATIVE B SECRETED HISTAMINE BINDING 22.5 KDA PACIFICUS 25.
 1    1               SALIVARY GLAND BkDa salivary gland protein B
           Ixodes scapularis                         SCAPULARIS PUTATIVE SECRETED PEPTIDE LIPOCALIN-LIKE BOOPHILUS MICROP
                                       26 IXODESs/hbp26
 1    1               SALIVARY GLAND B IXODESs/hbp23
           Ixodes scapularis                         SCAPULARIS
                                       histamine binding protein PUTATIVE A SECRETED HISTAMINE BINDING 22.5 KDA PACIFICUS 25.
 1    1               SALIVARY GLAND IXODESbinding protein A PUTATIVE B SECRETED HISTAMINE BINDING 22.5 KDA PACIFICUS 25.
           Ixodes scapularis                        s/hbp15
                                       histamine SCAPULARIS
 1    1               HISTAMINE BINDING IXODES SCAPULARIS SALIVARY GLAND B PUTATIVE A SECRETED 22.5 KDA PACIFICUS 25.
           Ixodes scapularis                        s/hbp23.1 biological_process unknown - cellular_component unknown
                                       histamine binding protein                 0.097

 1    1    Ixodes scapularis
                      PUTATIVE SECRETEDNeuropeptide-like biological_process unknown RNA binding||nucleic acid NPL 2 NEUROPEPTID
                                    GGY SALIVARY GLAND PEPTIDE IXODES SCAPULARIS NPL-2 PACIFICUS binding||binding
                                               s/immunity protein
                                                          ggy                 2E-13                   binding
 1    1    Ixodes scapularis
                      PUTATIVE SECRETEDNeuropeptide-like biological_process unknown elegans UNNAMED PRODUCT ARABIDOPSIS TH
                                    GGY SALIVARY GLAND PEPTIDE IXODES SCAPULARIS antimicrobial molecule activity
                                               s/immunity protein similar to immune C. structural constituent of cytoskeleton||structural m
                                                          ggy                 4E-17                   structural
63   29    Caenorhabditis briggsae
                      HYPOTHETICAL CAENORHABDITIS BRIGGSAE KERATIN ASSOCIATED 16-1 MUS MUSCULUS KERATIN-ASSOCIAT
                                    Gly GYG rich peptide structural molecule activity - cytoskeletonmolecule activity biogenesis - intermed
                                               s/immunity ggy                 1E-13       structural organization and
                                                                                                      structural molecule activity
 2    1               NPL-1
           Ixodes pacificus IXODES PACIFICUSrich peptide structural constituent of cytoskeleton - epidermis developmentactivity
                                    Gly GYG NPL 1 NPL-2ggy
                                               s/immunity 2 PUTATIVE 0.000000002SALIVARY GLAND PEPTIDE SCAPULARIS NEURO
                                                                         SECRETED                     structural of cytoskeleton||structural m
                                                                                          structural constituent molecule - intermediate fila



1    1                PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS SCAPULARISIN PREPROPROTEIN VARI
           Ixodes scapularis                  s/imm defensin
                                   preprodefensin

1    1                PUTATIVE SALIVARY kDa salivary protein with HEAA motif
           Ixodes pacificus                    s/microplusin
                                    11.8 SECRETED PEPTIDE WITH HEAHEAHEA REPEAT IXODES PACIFICUS MICROPLUSIN PREPR
1    1                PUTATIVE SALIVARY kDa HEAA salivary peptide HEAHEAHEA REPEAT IXODES PACIFICUS MICROPLUSIN PREPR
           Ixodes pacificus                    s/microplusin
                                    12.5 SECRETED PEPTIDE WITH



 1   102   Ixodes pacificus
                      TRUNCATED GLUTATHIONEperoxidase glutathione peroxidase activity glutathione catalytic activity - response to activity
                                      Glutathione h/ox
                                                   PEROXIDASE IXODES PACIFICUS PREDICTED SIMILAR TOactivity
                                                                                5E-42                      peroxidase activity||peroxidase lipid hy
                                                                                              - electron transporter PLASMA PRECURSOR G
 1    1    Ixodes scapularis
                      GLUTATHIONE PEROXIDASE IXODES SCAPULARIS PEROXIREDOXIN HAEMAPHYSALIS LONGICORNIS CG3083-P
                                      Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes
                                                   h/ox                         8E-75         peroxidase catalytic activity
                                                                                                           activity||oxidoreductase
                                                             cytosol - peroxidase activity - response to reactive oxygen species activity\, actin
14    4               UNNAMED
           Tetraodon nigroviridis PRODUCT TETRAODON NIGROVIRIDIS THIOREDOXIN PEROXIDASE HOMOactivity
                                      thioredoxin peroxidase thioredoxin peroxidase activity - I-kappaB phosphorylation
                                                   h/pm                            0          thioredoxin catalytic SAPIENS ANTIOXIDANT EN
                                                                                                           peroxidase activity||peroxidase activity
 7    3    Xenopus laevis
                      XENOPUS LAEVIS HYPOTHETICAL PONGO hydroperoxide reductase activity 3 HOMO SAPIENS ISOFORM A PRECUR
                                      thioredoxin peroxidase alkyl PYGMAEUS4E-85
                                                   h/pm                                       alkyl hydroperoxide reductase activity||oxidoreduc
                                                                                  PEROXIREDOXIN            catalytic activity
46   24    Pongo pygmaeus
                      HYPOTHETICAL PONGO PYGMAEUS PEROXIREDOXIN 3 HOMO SAPIENS ISOFORM A reductase activity||oxidoreduc
                                      thioredoxin peroxidase alkyl hydroperoxide reductase activity
                                                   h/pm                         6E-84         alkyl hydroperoxide activity
                                                                                                           catalytic PRECURSOR AOP-1 SP-22

 6    6               CG7484-PB DROSOPHILA MELANOGASTER ANOPHELES GAMBIAE selenium binding||binding
           Drosophila melanogaster             s
                                   Selenoprotein/selenop selenium binding 5E-32                    binding
                                                                                       STR. PEST PSEUDOOBSCURA SELENOPROT
37   28                            Selenoprotein M
                                               s/selenop endoplasmic reticulum - Golgi apparatus - molecular_function unknown - biologic
                                                                          3E-15        molecular_function unknown
                                                                                                   molecular_function RERIO
                      Q8VHC3 SELM_MOUSE SELENOPROTEIN M PRECURSOR SELM Q8WWX9 SELM_HUMAN DANIOunknownMUS MUS
3   8                           selenoprotein RERIO W2B UNNAMED PRODUCT TETRAODON NIGROVIRIDIS RIKEN CDNA MUSC
                                            s/selenop molting cycle (sensu Insecta) - learning and/or memory - learning - grooming beh
        Danio rerio SELENOPROTEIN W2A DANIOW2A                          0.033

1   1              SALIVARY GLAND IXODES SCAPULARIS ANTICOMPLEMENT ISAC-1 PACIFICUS ISAC 1 SALP9 CRYPTOSPORIDIU
        Ixodes scapularis                      s/isac
                                  anticomplement
1   1              SALIVARY GLAND IXODES SCAPULARIS ANTICOMPLEMENT ISAC-1 PACIFICUS ISAC 1 SALP9 HYPOTHETICAL CR
        Ixodes scapularis                      s/isac
                                  anti-complement
1   1              SALIVARY GLAND IXODES SCAPULARIS ANTICOMPLEMENT ISAC-1 PACIFICUS ISAC 1 SALP9 DROSOPHILA PSE
        Ixodes scapularis                      s/isac
                                  anti-complement
1   1              ANTICOMPLEMENT IXODES s/isac
        Ixodes scapularis                      SCAPULARIS SALIVARY GLAND ISAC-1 PACIFICUS ISAC 1 SALP9 PREDICTED NEUR
                                  anticomplement
1   1              ANTICOMPLEMENT IXODES s/isac
        Ixodes scapularis                      SCAPULARIS SALIVARY GLAND ISAC-1 PACIFICUS ISAC 1 SALP9 HYPOTHETICAL CA
                                  anticomplement protein
1   1              SALP9          salp9 anticlomplement family development (sensu
                                               s/isac     larval         ANTICOMPLEMENT growth - reproduction
        Ixodes scapularis IXODES SCAPULARIS ISAC-1 PACIFICUS ISAC 1 0.074 Nematoda) - SALIVARY GLAND HYPOTHETICAL CA
1   1              SALIVARY GLAND IXODES SCAPULARIS ANTICOMPLEMENT ISAC-1 PACIFICUS ISAC 1 SALP9 UNCHARACTERIZE
        Ixodes scapularis                      s/isac
                                  20 kDa salivary gland protein

9   7              PUTATIVE SECRETED SALIVARY protein PEPTIDE IXODES SCAPULARIS 10.2 KDA
        Ixodes scapularis                            s/VCRNH
                                        12.3 kDa salivary GLAND
                                                     s/VCRNH
                                        6.8 kDa peptide
1   2              HYPOTHETICAL BACILLUS s/VCRNH
                                        7.2 kDa peptide
        Bacillus subtilis subsp. subtilis str. 168 SUBTILIS SUBSP. STR. 168 BETA-LACTAMASE HOMOLOG YBBE_BACSU PRECURSOR
1   1              PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS 10.2 KDA LEUCYL-TRNA SYNTHETASE B
        Ixodes scapularis                            s/WC10
                                        10 kDa peptide
1   1   Ixodes scapularis
                   PUTATIVE 10.2 KDAkDa peptide IXODES SCAPULARIS SALIVARY GLAND PEPTIDE 6.4 EPIDERMALactivity||transme
                                        10 SECRETED                                0.011         epidermal epidermal growth factor receptor FAC
                                                                                                            signal transducer activity
                                                     s/WC10 epidermal growth factor receptor activity -growth factor receptor GROWTHsigna
1   1   Ixodes scapularis
                   PUTATIVE 10.2 KDAkDa peptide IXODES SCAPULARIS SALIVARY GLAND PEPTIDE 6.4 EPIDERMALactivity||transme
                                        10 SECRETED                                0.019         epidermal epidermal growth factor receptor FAC
                                                                                                            signal transducer activity
                                                     s/WC10 epidermal growth factor receptor activity -growth factor receptor GROWTHsigna
1   1              PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS 10.2 KDA
        Ixodes scapularis                            s/WC10
                                        10 kDa peptide
7   1              PUTATIVE SECRETED SALIVARY GLAND opioid PFAM domain
        Ixodes scapularis                            s/WC10
                                        10 kDa WC peptide weak PEPTIDE IXODES SCAPULARIS 10.2 KDA 6.4 GALLERIA MELLONELLA S
1   1              PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS 10.2 KDA 6.4 RELATED TO CARBOXYPE
        Ixodes scapularis                            s/WC10
                                        10.2 kDa WC salivary protein
1   1              PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS 10.2 KDA 6.4 PREDICTED HYPOTHETICA
        Ixodes scapularis                            s/WC10
                                        10.3 salivry WC peptide
8   1              PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS 10.2 KDA PRECURSOR CRYPTOCOCCU
        Ixodes scapularis                            s/WC10
                                        10.5 kDa peptide
1   1              PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS 10.2 KDA UNNAMED PRODUCT TETRAO
        Ixodes scapularis                            s/WC10
                                        11 kDa peptide
2   8              PUTATIVE 10.2 KDA SECRETED IXODES SCAPULARIS SALIVARY GLAND PEPTIDE 6.4 AFL110CP ASHBYA GOSSY
        Ixodes scapularis                            s/WC10
                                        DGVCR family 10 kda
1   1              PUTATIVE 10.2 KDA SECRETED IXODES SCAPULARIS SALIVARY GLAND PEPTIDE 6.4 HYPOTHETICAL CAENORH
        Ixodes scapularis                             kDa secreted family
                                        putative 10.2s/WC10
1   1              PUTATIVE 10.2 KDA SECRETED IXODES SCAPULARIS SALIVARY GLAND PEPTIDE 6.4 PROENKEPHALIN HETERO
        Ixodes scapularis                             kDa secreted family
                                        putative 10.2s/WC10
7   1              PUTATIVE SECRETED SALIVARY secretedPEPTIDE IXODES SCAPULARIS 10.2 KDA 6.4 UNNAMED PRODUCT TETR
        Ixodes scapularis                             kDa GLAND family
                                        putative 10.2s/WC10
1   1              PUTATIVE 10.2 KDA SECRETED IXODES SCAPULARIS SALIVARY GLAND PEPTIDE 6.4 EPIDERMAL GROWTH FAC
        Ixodes scapularis                             kDa secreted family
                                        putative 10.2s/WC10
1   1              PUTATIVE 10.2 KDA SECRETED IXODES SCAPULARIS SALIVARY GLAND PEPTIDE 6.4 TRANSCRIPTIONAL REGUL
        Ixodes scapularis                             kDa secreted family
                                        putative 10.2s/WC10
1   1              PUTATIVE 10.2 KDA SECRETED IXODES SCAPULARIS SALIVARY GLAND PEPTIDEvenoms
        Ixodes scapularis                             kDa secreted family - similar to cys rich domain of snake 6.4 METALLOPROTEINASE PR
                                        putative 10.2s/WC10
1   7              PUTATIVE 10.2 KDA SECRETED IXODES SCAPULARIS SALIVARY GLAND PEPTIDE 6.4 PROENKEPHALIN HETERO
        Ixodes scapularis                            s/WC10
                                        opioid putative 10.2 kDa secreted protein - similar to opioid
2   8              PUTATIVE 10.2 KDA SECRETED IXODES SCAPULARIS SALIVARY GLAND PEPTIDE 6.4 ANTHRANILATE PHOSPHO
        Ixodes scapularis                             kDa secreted protein family
                                        putative 10.2s/WC10
1   1              PUTATIVE 10.2 KDA SECRETED IXODES SCAPULARIS SALIVARY GLAND PEPTIDE 6.4 GROUP I PHOSPHOLIPASE
        Ixodes scapularis                            s/WC10
                                        putative 9.9 kDa secreted peptide
1   1              PUTATIVE SECRETED SALIVARY salivary gland peptide
        Ixodes scapularis                            s/WC10
                                        putative secreted GLAND PEPTIDE IXODES SCAPULARIS 10.2 KDA 6.4 CAT2_RICCO CATALASE IS
1   1              PUTATIVE SECRETED SALIVARY salivary gland peptide 0.015
        Ixodes scapularis                            s/WC10 cellular_component unknown
                                        putative secreted GLAND PEPTIDE IXODES SCAPULARIS 10.2 KDA UNKNOWN ARABIDOPSIS THA
1   1              PUTATIVE SECRETED SALIVARY secretedPEPTIDE IXODES SCAPULARIS 10.2 KDA
        Ixodes scapularis                             kDa GLAND
                                        putative 10.2s/WC10 family protein
1   1              PUTATIVE 10.2 KDA SECRETED IXODES SCAPULARIS SALIVARY GLAND PEPTIDE HYPOTHETICAL ARGININE RE
        Ixodes scapularis                             kDa secreted
                                        putative 10.2s/WC10 long family
8   1              PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS 10.2 KDA
        Ixodes scapularis                            s/WC10 short
                                        4.3 kDa salivary peptide
8   5              PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS UNNAMED PRODUCT TETRAODON NIGR
        Ixodes scapularis                            s/WC10 short
                                        4.8 kDa peptide
8   1   Ixodes scapularis
                   PUTATIVE SECRETED SALIVARY secretedPEPTIDE binding - protein-nucleus10.2 KDAnuclear pore binding||binding
                                        putative 10.2s/WC10 short family
                                                      kDa GLAND protein IXODES SCAPULARISprotein binding||protein
                                                                RAN                0.075         RAN import - NUCLEOPORIN RBP2_HUMAN
                                                                                                            binding
1   1              PUTATIVE SECRETED SALIVARY secretedPEPTIDE IXODES SCAPULARIS 10.2 KDA 6.4 DYNEIN HEAVY CHAIN ENC
        Ixodes scapularis                             kDa GLAND
                                        putative 10.2s/WC10 short family
8   1              PUTATIVE SECRETED SALIVARY secretedPEPTIDE IXODES SCAPULARIS 10.2 KDA 6.4 IMIDAZOLEGLYCEROL-PHO
        Ixodes scapularis                             kDa GLAND
                                        putative 10.2s/WC10 short family
8   1              PUTATIVE SECRETED SALIVARY secretedPEPTIDE IXODES SCAPULARIS 10.2 KDA UNNAMED PRODUCT HOMO S
        Ixodes scapularis                             kDa GLAND
                                        putative 10.2s/WC10 short family
1   1              PUTATIVE 6.4 KDA SECRETED IXODES SCAPULARIS 10.2 SALIVARY GLAND PEPTIDE 36KDA PROTEASE BACILLU
        Ixodes scapularis                            s/WC10 short
                                        putative 6.3 kDa secreted p
1   1              PUTATIVE SECRETED SALIVARY peptide of 9.4 kDa IXODES SCAPULARIS 10.2 KDA 6.4 AMP-DEPENDENT SYNTHE
        Ixodes scapularis                            s/WC10 short
                                        putative secreted GLAND PEPTIDE

1   1              PUTATIVE PEPTIDEkDa proteinIXODES PACIFICUS SALIVARY GLAND 16 KD SCAPULARIS SECRETED 11.9 ANOPH
        Ixodes pacificus         12 14.4 KDA  s/LPTS
1   1              PUTATIVE PEPTIDE 11.9 KDA IXODES PACIFICUS SALIVARY GLAND 16 KD SCAPULARIS 14.4 SECRETED CIRCUM
        Ixodes pacificus                      s/LPTS
                                 14.3 kDa peptide
1   1              PUTATIVE PEPTIDE 11.9 KDAprotein PACIFICUS SALIVARY GLAND 16 KD SCAPULARIS 14.4 SECRETED 11.3 HY
        Ixodes pacificus                        IXODES
                                 14.5 salivarys/LPTS
1   1              PUTATIVE PEPTIDE 14.4 KDAprotein PACIFICUS SALIVARY GLAND 16 KD SCAPULARIS SECRETED 11.9 HOMEO
        Ixodes pacificus                        IXODES biological_process unknown
                                 15.1 salivarys/LPTS                        0.024
1   1   Ixodes pacificus
                   PUTATIVE PEPTIDE 14.4 KDAprotein PACIFICUS SALIVARY GLAND 16 biological_process SECRETED UNNAMED P
                                 15.8 salivarys/LPTS
                                                IXODES translation initiation factor activity - KD SCAPULARISregulator activity
                                                                            0.001                       translation unknown - cellular_compo
                                                                                           translation initiation factor activity||translation facto
1   1              PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS 16 KD 14.4 KDA PACIFICUS 11.9 ARABID
        Ixodes scapularis                     s/LPTS     biological_process unknown - cellular_component unknown
                                 16 kDa salivary gland protein              0.028
1   1   Ixodes scapularis
                   SALIVARY GLAND 16 KDprotein SCAPULARIS PUTATIVE PEPTIDE ARF guanyl-nucleotide SECRETED 11.9 HYPOT
                                 cys rich IXODES
                                              s/LPTS                        0.005           14.4 KDA PACIFICUS exchange factor Golgi ves
                                                                                                        enzyme regulator activity
                                                         ARF guanyl-nucleotide exchange factor activity - intra-Golgi transport - activity||g
1   3   Ixodes pacificus
                   PUTATIVE PEPTIDE 14.4 peptide 14.4 kDa
                                 putative KDA IXODES PACIFICUS SALIVARY GLANDmembrane signal transducer activity 11.9 HYPOT
                                              s/LPTS     extracellular space - integral to G-protein coupled receptor activity||transmembran
                                                                            0.095            16 KD SCAPULARIS SECRETED
1   1              PUTATIVE SECRETED SALIVARY salivary gland peptide
        Ixodes scapularis                     s/LPTS
                                 putative secreted GLAND PEPTIDE IXODES SCAPULARIS 14.4 KDA PACIFICUS 16 KD 11.9 PHOSP
1   1              SALIVARY GLAND 16 KDgland 14 kD protein
        Ixodes scapularis                     s/LPTS
                                 salivary IXODES SCAPULARIS PUTATIVE PEPTIDE 14.4 KDA PACIFICUS SECRETED 11.9 SIMILAR
1   1   Ixodes scapularis
                   SALIVARY GLAND 16 kDaIXODES protein
                                 15.3 KD salivary SCAPULARIS PUTATIVEunknown molecular_function unknown unknown SURFAC
                                              s/LPTS family
                                                         cellular_component PEPTIDE 14.4 KDA PACIFICUS SECRETED 11.9
                                                                            0.003                       molecular_function



1   1              PUTATIVE SERPIN IXODES SCAPULARIS SECRETED SALIVARY inhibitor activityenzyme regulator - cytosol
        Ixodes scapularis       Serpin    s/serpin                  1E-21        serine-type endopeptidase inhibitor activity||endop
                                                                                                - protein binding activity
                                                   serine-type endopeptidase GLAND PEPTIDE LIMULUS INTRACELLULAR COA
1   1   Ixodes scapularis
                   PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS LIMULUS INTRACELLULAR activity||endop
                                Serpin    s/serpin                  8E-55        serine-type endopeptidase inhibitor COAGULATIO
                                                   serine-type endopeptidase inhibitor activityenzyme regulator activity

1   1              PUTATIVE SECRETED CYSTATIN cystatin 2 SCAPULARIS PRECURSOR ORNITHODOROS MOUBATA CYSTATIN-2 2
        Ixodes scapularis                    s/cystatin biological_process unknown cysteine protease inhibitor activity||endopeptidase
                                putative secreted IXODES                0.000005              enzyme regulator activity
1     1               PUTATIVE SECRETED CYSTATIN IXODES SCAPULARIS CYSTATIN-2 PRECURSOR ORNITHODOROS MOUBATA 2
           Ixodes scapularis                   s/cystatin biological_process unknown cysteine protease inhibitor activity||endopeptidase
                                   secreted cystatin                       0.0002               enzyme regulator activity

7     4    Lonomia obliqua
                     PROTEASE INHIBITOR 6 secreted TIL 9.3
                                   Salivary LONOMIA OBLIQUA HYPOTHETICAL receptor activityactivity||signal transducer activity CYS
                                                s/til                        0.003     receptor - caspase activator activity - TRAIL
                                                                                                  signal transducer
                                                         receptor activity - death BRANCHIOSTOMA BELCHERI TSINGTAUNESE bind
1     1    Pimpla hypochondriaca
                     CYSTEINE-RICH similar to6 PIMPLA HYPOCHONDRIACA 0.005
                                   VENOM parasitoid wasp cysteine-rich venom protein biological_process unknown -RICH HYPOTHETIC
                                                s/til                        CVP6_PIMHY PRECURSOR CYSTEINE unknown
                                                                                       6          molecular_function
                                                         molecular_function unknown - molecular_function unknown cellular_component

391   21              RATTUS
           Rattus norvegicus NORVEGICUS HYPOTHETICAL CRYPTOSPORIDIUM HOMINIS ARABIDOPSIS activity||transcription regulator
                                     11 kDa peptide mucin transcription factor activity - zinc ion bindingfactor THALIANA CONTAINS WEAK
                                                  s/muc                     0.000000005       transcription - regulationregulator activity DNA-de
                                                                                                           transcription of transcription,
236   21              HYPOTHETICAL CRYPTOSPORIDIUM HOMINIS SIMILAR TO MELLIFERA UNNAMED PRODUCT YARROWIA LIPOLY
           Cryptosporidium hominis                s/muc
                                     probable mucin           basement membrane0.00005
178    2              MANNOPROTEIN SRP1P mucin
           Saccharomyces cerevisiae probable TIP1P FAMILYcell wall (sensu Fungi) - molecular_function unknown UNDER ANAEROBIC CON
                                                  s/muc                         0.0007        molecular_function unknown unknown
                                                                                                           molecular_function
                                                               SERINE-ALANINE-RICH PROTEINS EXPRESSED - biological_process unkno
209   72              ISOFORM C
           Caenorhabditis elegans CAENORHABDITIS ELEGANS VENOM ALLERGEN (sensu Animalia) - physiologicalCG4835-PA DROSOPH
                                     probable mucin
                                                  s/muc                          0.004        extracellular LON-1 LON process
                                                                                                           structural molecule activity
                                                              embryonic development 5 BODY LENGTH matrix structural constituent||structura
 1     1              IXODES
           Ixodes scapularis SCAPULARIS ISOFORM A DROSOPHILA MELANOGASTER HYPOTHETICAL HUMAN HERPESVIRUS 1 IMM
                                     IS3 family s/mucin                          0.096        glucan endo-1\,3-beta-D-glucosidase activity||hyd
                                                                                                           catalytic activity
                                                              glucan endo-1,3-beta-D-glucosidase activity - cell separation during cytokinesis -
 1     1   Ornithodoros moubata
                      MUCIN PERITROPHIN-LIKE PRECURSOR ORNITHODOROS MOUBATA PERITROPHIN LIKE SIMILAR TO MELLIFER
                                     mucin/peritrophin-like protein activity - proteolysis and peptidolysis
                                                  s/muc chit trypsin             0.027        trypsin activity||serine-type endopeptidase activity
                                                                                                           catalytic activity
 1     1   Ornithodoros moubata
                      MUCIN PERITROPHIN-LIKE PRECURSOR ORNITHODOROS MOUBATA PERITROPHIN LIKE SIMILAR TO MELLIFER
                                     mucin/peritrophin-like protein activity - proteolysis and peptidolysis
                                                  s/muc chit trypsin             0.027        trypsin activity||serine-type endopeptidase activity
                                                                                                           catalytic activity

 1     1   Ixodes scapularis
                       PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS JERDOSTATIN TRIMERESURUS JERDON
                                     IS6 family member - venom and hormone-like
                                                   s/IS6                          0.02        receptor activity||signal - protein heterodimerizatio
                                                                                                          signal transducer activity
                                                             receptor activity - calcium ion binding - protein binding transducer activity
 3     1   Ixodes scapularis
                       PUTATIVE SECRETED SALIVARY GLAND PEPTIDE -IXODES SCAPULARIS SIMILAR binding||glycosaminoglycan bindin
                                     IS6 family member - venom and hormone-like
                                                   s/IS6                         0.009
                                                             extracellular extracellular space            binding
                                                                                              hyaluronic acid TO MUSCULUS PREDICTED DK
251   30   Gallus gallus
                       PREDICTED SIMILAR TO DKK-1 GALLUS DKK 1 UNNAMED PRODUCT TETRAODON NIGROVIRIDIS DICKKOPF1 DA
                                     similar to Dickkopf weakly similar to a extracellular space thrombospondin family
                                                   s/IS6                        0.00007       signal transducer activity
                                                             extracellular - tick member of the           signal transducer activity
                                     IS6 family member - venom and hormone-like

1     1               PUTATIVE SECRETED SALIVARY protein PEPTIDE IXODES SCAPULARIS PACIFICUS SURFACE BACILLUS CEREU
           Ixodes scapularis                    s/12kd family
                                   11.6 kDa salivary GLAND
1     1               PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS PACIFICUS HYPOTHETICAL GALLUS PR
           Ixodes scapularis                    s/12kd family
                                   12 kDa protein
1     1               PUTATIVE SECRETED SALIVARY salivary gland peptide
           Ixodes scapularis                    s/12kd family
                                   putative secreted GLAND PEPTIDE IXODES SCAPULARIS PACIFICUS RIKEN CDNA MUSCULUS UN

1     1               SALIVARY GLAND AkDa salivary gland protein A
           Ixodes scapularis                    SCAPULARIS PUTATIVE SECRETED PEPTIDE HYPOTHETICAL CAENORHABDITIS EL
                                   26 IXODESs/hbp
1     1               PUTATIVE SECRETED SALIVARY26 kDa salivary gland proteinSCAPULARIS A SHOCK HTPG METHYLOCOCCUS CAP
           Ixodes scapularis                   s/hbp
                                   weakly similar to GLAND PEPTIDE IXODES A

1      1              PUTATIVE SALIVARY SECRETEDkDa
           Ixodes pacificus                      s/30 PEPTIDE IXODES
                                    putative secreted protein of 29 kDa PACIFICUS CYTOTOXIN BACTERIOPHAGE PHI CTX UNNAMED
1     11              PUTATIVE SALIVARY SECRETEDkDa
           Ixodes pacificus                      s/30 PEPTIDE IXODES
                                    putative secreted protein of 29 kDa PACIFICUS CRYSTAL 34K BACILLUS THURINGIENSIS CFAA_B

                                               s/tox1
                                    5.6 kDa peptide
1     1               PUTATIVE SALIVARY SECRETED PEPTIDE IXODES PACIFICUS PREDICTED MAGNAPORTHE GRISEA UNNAMED P
           Ixodes pacificus                    s/tox1
                                    6.6 kDa peptide

37     5               TWO-COMPONENT   Same family as ww
                                                   HISTIDINE KINASE one exon - see psiblast report
           Lactobacillus acidophilus NCFM SENSORs/ww protein withoutLACTOBACILLUS ACIDOPHILUS NCFM COMPONENT HYDROLAS
27    42               NPC2-PROV XENOPUS TROPICALIS ALLERGEN LIKE IXODES RICINUS UNKNOWN SCHISTOSOMA JAPONICUM S
           Xenopus tropicalis                     s/ww
                                       WW secreted protein

 1     1   Ixodes scapularis
                       PUTATIVE SECRETED CARBOXYPEPTIDASE IXODES SCAPULARIS carboxypeptidase D activity PYGMAEUS SIMILAR
                                      Serine carboxypeptidases (lysosomal cathepsin A)
                                                   s/enz carboxypeptidase
                                                               cellular_component unknown HYPOTHETICAL PONGO
                                                                                  7E-23                    catalytic activity||serine carboxypeptid
 1     1   Ixodes scapularis
                       SALIVARY 10 IXODES SCAPULARIS enzyme precursor- proteolysis and peptidolysis
                                      Trypsin - Proclotting LIMULUS activity
                                                   h/imm                          4E-65       trypsin activity||serine-type endopeptidase activity
                                                                                                           catalytic activity
                                                               trypsin CLOTTING ENZYME EC PRECURSOR HORSESHOE CRAB TACHYPL
 8    30               SIMILAR TO SERINE PROTEINASE APIS protease
           Apis mellifera             Trypsin      s/enz serine MELLIFERA ANOPHELES GAMBIAE STR. PEST CG9372-PA PROTEASE pe
                                                               plasma membrane - serine-type endopeptidase activity - proteolysis and peptido
                                                                                  9E-33       serine-type catalytic activityactivity||serine-type PA
                                                                                                           endopeptidase
636    1   Caenorhabditis briggsae
                       HYPOTHETICAL CAENORHABDITIS BRIGGSAE ELEGANS ENDOTHELIN-CONVERTING 2F66 ENDOTHELIN CONVE
                                      M13 family peptidase probaly truncated 0.00004
                                                   s/enz       reproduction                                binding
                                                                                              zinc ion binding||transition metal ion binding||meta
 1     1               ANGIOTENSIN-CONVERTING ENZYME-LIKE ANGIOTENSIN CONVERTING ENZYME LIKE PEPTIDYL-DIPEPTIDASEa
                                      Angiotensin I-convertingpeptidyl-dipeptidase A peptidases
                                                   h/en kin                       1E-10        metamorphosis (sensu Insecta)
                                                                                                           catalytic A activity||metallopeptidase
                                                                enzymes - M2 family activity -peptidyl-dipeptidase activity
 1     1               DROSOPHILA small ribonucleaseribonuc
                                                   s/enz       embryonic CERATITIS (sensu Animalia) - larval GAMBIAE STR. PEST SIMILA
                                                                                  1E-11
           Drosophila melanogaster MELANOGASTER RIBONUCLEASE developmentCAPITATA ANOPHELES development (sensu Nematoda
73    29   Ixodes pacificus
                       PUTATIVE SALIVARY SECRETED PEPTIDE IXODES endoplasmic ANOPHELES GAMBIAEactivityPEST SIMILAR TO ME
                                      truncated phospholipase
                                                   s/enz pl                       3E-13       phospholipase A2 activity||phospholipase activity|
                                                                                                           catalytic STR.
                                                               intracellular - PACIFICUS reticulum - Golgi apparatus - phospholipase A2 activit

12    3                DROSOPHILA similar to scorpion protein - conserved Cys framework
                                                      s/scorp
           Drosophila pseudoobscura PSEUDOOBSCURA CG9896-PA MELANOGASTER ANOPHELES GAMBIAE STR. PEST CG9896-LIKE M
                                                      s/1.4
                                         1.4 kDa salivary peptide with 4 cysteines
                                                      s/1.6
                                         1.6 kDa salivary peptide
                                                      s/1.7
                                         1.7 kDa peptide
                                                      s/1.8
                                         1.8 kDa peptide
125   22               PUTATIVE MALATE kDa salivary peptide
                                         2.4          s/2.4
           Bordetella bronchiseptica RB50 L-LACTATE DEHYDROGENASE BORDETELLA BRONCHISEPTICA RB50 LACTATE
                                                      s/2.6
                                         2.6 kDa peptide
139   15               THIOL DISULFIDE INTERCHANGE BURKHOLDERIA CEPACIA HYPOTHETICAL 2 RRNA EXTERNAL TRANSCRIBED
                                                      s/2.7
           Burkholderia cepacia R1808 2.7 kDa salivary peptide
                                                      s/2.8
                                         2.8 kDa peptide
                                                      s/2.9
                                         2.9 kDa peptide
                                                      s/3.6
                                         3.86 kDa peptide
 1     1               PUTATIVE 4.3 KDA SECRETED IXODES SCAPULARIS SAPIENS TRANS-ACTIVATED BY HEPATITIS C VIRUS CORE
           Ixodes scapularis                          s/7.2
                                         putative7.2 kDa secreted peptide
 1     1               PUTATIVE SALIVARY SECRETED PEPTIDE IXODESpacificus
           Ixodes pacificus                            peptide - identical regulation0.051
                                                                                      of growth rate - larval development (sensu Nematoda) - growt
                                         4 kDa YYYYs/imm yyyypositiveto Ix. PACIFICUS HYPOTHETICAL CAENORHABDITIS BRIGGSAE BR
504    7               PUTATIVE HELICASE STREPTOMYCES VIOLACEORUBER HYPOTHETICAL CAENORHABDITIS ELEGANS FINGER
           Streptomyces violaceoruber 4.1 kDa peptide s/7.1
 1     1               PUTATIVE SECRETED PEPTIDE 6.3 KDA IXODES PACIFICUS 4.99 PREDICTED SIMILAR TO RING FINGER 127 GAL
           Ixodes pacificus                           s/7.5
                                         7.5 kDa peptide
87     5               PUTATIVE MEMBRANE ORYZA
                                         7.4 kDa      s/7.4
           Oryza sativa (japonica cultivar-group) peptideSATIVA JAPONICA CULTIVAR-GROUP CULTIVAR GROUP UNKNOWN ARABIDOPSI
653   18               HYPOTHETICAL ORYZAYIYI peptides/7.8
           Oryza sativa (japonica cultivar-group) SATIVA JAPONICA CULTIVAR-GROUP CULTIVAR GROUP
                                                      s
                                         5 kDa peptide/5
23    44               HYPOTHETICAL ORYZA peptide
                                         5.98 kDa     s/5.8
           Oryza sativa (japonica cultivar-group) SATIVA JAPONICA CULTIVAR-GROUP CULTIVAR GROUP
 279   11                 CONSERVED HYPOTHETICAL SEE MYCOPLASMA PNEUMONIAE M129 HOMOLOG STRAIN ATCC Y042_MYCPN RI
                                           6.7          s/6.7
             Mycoplasma pneumoniae M129 kDa secreted peptide
1258   40                  roretzi         putative secreted peptide of 8.4 kDa
                                                        s/8.4
             HalocynthiaNOTCH HOMOLOG SEA SQUIRT HALOCYNTHIA RORETZI HRNOTCH HYPOTHETICAL ARABIDOPSIS THALIANA
 187    6                 pomeroyi DSS-3 8.8 kDa peptides/8.8
             Silicibacter TRANSPORTER TRANSMEMBRANE ATP-BINDING PUTATIVE SILICIBACTER POMEROYI DSS-3 BINDING DSS 3 GIA
  2     3                 PUTATIVE PEPTIDE 11.9 KDA IXODES PACIFICUS HYPOTHETICAL AVICENNIA MARINA PROBABLE AMINO ACID T
             Ixodes pacificus                           s/11.9
                                           weakly similar to I. pacificus ppolypeptide of same size
 153   25                 HYPOTHETICAL BORDETELLA PARAPERTUSSIS CONSERVED BRONCHISEPTICA RB50 RIM101P CANDIDA DUBLI
             Bordetella parapertussis                   s/9.4
                                           9.4 kda salivary peptide
 14    13                 SECRETED
             Ornithodoros moubata PK-4 9.7 kDa peptideORNITHODOROSadaptor protein activity - signal adaptor transducer activityELEGANS PU
                                           PRECURSOR similar to Ornithodorus salivary peptide - Gly richtransduction - plasma membrane - sign
                                                        s/9.7        SH3/SH2 MOUBATA PK 4 HYPOTHETICAL CAENORHABDITIS
                                                                                         0.02        SH3/SH2 signal protein activity||transmembrane
  1     1                 PUTATIVE SECRETED SALIVARY salivary gland peptide 0.025
             Ixodes scapularis                          s/10         biological_process unknown - cellular_component unknown
                                           putative secreted GLAND PEPTIDE IXODES SCAPULARIS HYPOTHETICAL ASPERGILLUS NIDULAN
1285   89                 HYPOTHETICAL 10.5 kDa peptide similar to hbp18
                                                        s/12kDa
             Plasmodium falciparum 3D7 PLASMODIUM FALCIPARUM 3D7 PUTATIVE SALIVARY SECRETED PEPTIDE IXODES PACIFICUS
  1     1                 PUTATIVE SECRETED SALIVARY salivary gland peptide
             Ixodes scapularis                          s/12.2
                                           putative secreted GLAND PEPTIDE IXODES SCAPULARIS SUGAR PENTULOSE HEXULOSE KINASE
 119    6                 PREDICTED MEMBRANE salivary protein
                                           ATCC 13032   s/14.3
             Corynebacterium glutamicum 12.3 kDa CORYNEBACTERIUM GLUTAMICUM ATCC FUMARASE SYNECHOCOCCUS ELONGATUS
  1     1                 ANOPHELES GAMBIAE STR.s/13 SIMILAR TO MELLIFERA CG7781-PA DROSOPHILA MELANOGASTER PSEUDOO
             Anopheles gambiae str. PEST                 PEST
                                           unknown conserved
 188   53                 SEPTUM           14.5 kDa salivary protein
                                                        s/14.5
             Aquifex aeolicus VF5 SITE-DETERMINING MIND AQUIFEX AEOLICUS VF5 DIVISION INHIBITOR PLACEMENT MIND1 SITE DETE
 492   26                 UNNAMED
             Tetraodon nigroviridis PRODUCTkDa salivary protein
                                           14.9 TETRAODON NIGROVIRIDIS GALNT10-MUSCULUS N-acetylgalactosaminyltransferase activityac
                                                        s/14.9                          0.015        polypeptidecatalytic activity
                                                                                                                   N-acetylgalactosaminyltransferase
                                                                     O-linked glycosylation polypeptide UDP-N-ACETYL-ALPHA-D-GALACTOSAM
 38     1    Drosophila melanogaster
                          CG7296-PA DROSOPHILA MELANOGASTER PSEUDOOBSCURA development binding acidRECOGNITION PARTIC
                                           Gly rich peptide
                                                        s/Gly-Pro rich                 0.0004        RNA binding||nucleic
                                                                     extracellular matrix - heart XENOPUS LAEVIS SIGNAL binding||binding
  1     1                 PUTATIVE SECRETED SALIVARY GLANDprotein
             Ixodes scapularis                          s/16
                                           putative salivary secreted PEPTIDE IXODES SCAPULARIS HYPOTHETICAL ORYZA SATIVA JAPONI
 208   25                 TRANSCRIPTIONAL REGULATOR GNTR
                                           17.7 kDa     s/17.7
             Agrobacterium tumefaciens str. C58 salivary protein FAMILY AGROBACTERIUM TUMEFACIENS STR. C58 AGR_L_244P TRANS
 182   70                 HYPOTHETICAL PLASMODIUM YOELII FALCIPARUM 3D7 CYCLIC NUCLEOTIDE-GATED CHANNEL ion binding||meta
             Plasmodium yoelii yoelii                   s/17.9        from Babesia 0.0008            zinc ion binding||transition metal BETA SUBUNIT
                                           17.9 kDa protein maybeintracellular - cytoplasm - zinc ion binding binding
 26    112   Homo sapiens                  18.1 salivarys/keratin associated
                                                         protein
                          KERATIN ASSOCIATED 9.5 HOMO SAPIENS Q9BYQ1 KR95_HUMAN KERATIN-ASSOCIATED 9-5 ULTRAHIGH SULF
  6    35                 DROSOPHILA antigen 5 s/ag5                 cell wall (sensu Fungi) - molecular_function unknown - biological_process unkno
                                                                                        3E-26        molecular_function unknown unknown
             Drosophila pseudoobscura PSEUDOOBSCURA MELANOGASTER ANOPHELES GAMBIAE STR. PEST UNKNOWN FUNCTION HA  molecular_function
 506   73                                  20 kDa secreted
                                                         SEQUENCE
                          ORFVEG106 RANDOM CDNAs/20 protein UNNAMED PRODUCT TETRAODON NIGROVIRIDIS HYPOTHETICAL CAE
 717   120                                  RICH REPEAT peptide
                                                        s/5.8
             Bos taurus NACHT LEUCINE5.8 kDa salivary PYD CONTAINING 5 BOS TAURUS MATERNAL ANTIGEN THAT EMBRYO REQUIRE
 448   17                 EXORIBONUCLEASE R THIOBACILLUS DENITRIFICANS ATCC GLYCOSYLTRANSFERASE LEGIONELLA PNEUMOP
                                           32.5 kDa     s/32.5
             Thiobacillus denitrificans ATCC 25259 salivary protein
 57     2                 IXODERIN B IXODES RICINUS PUTATIVE SALIVARY SECRETED PEPTIDE - sugar binding - opsonization - antimicrobia
             Ixodes ricinus                             s/angiopo antigen binding 2E-27              antigen binding||binding
                                                                                                                  binding
                                           Ficolin and related extracellular proteins- calcium ion binding PACIFICUS OMFREP ORNITHODOROS M
  1     1                 PUTATIVE SECRETED SALIVARY GLAND PEPTIDE IXODES SCAPULARIS PREDICTED SIMILAR TO KERATINOCYT
             Ixodes scapularis                          s/keratinocyte-like
                                                                     biological_process 2unknown
                                           similar to keratinocytes associated protein5E-16
  1     1    Ixodes scapularis
                          CALRETICULIN IXODES SCAPULARIS PACIFICUS PAVLOVSKYI PERSULCATUS corepressor activity||transcriptiontran
                                           Calreticulin s/calr                             0         transcriptionion storage regulator activity
                                                                                                                    NIPPONENSIS MURIS RICINUS JE
                                                                     transcription corepressor activity - calcium transcriptionactivity - regulation of cof
 888   24                 SIMILAR
             Rattus norvegicus TO RPGR-INTERACTING RATTUS NORVEGICUSprotein binding - visual binding
                                           Very charged secreted protein -- axonemeclusters with calreticulins perception - eye photoreceptor cell TH
                                                        h/vc         cilium Psiblast - RPGR INTERACTING HYPOTHETICAL ARABIDOPSIS de
                                                                                        3E-11        protein binding||binding
 658   25                 HYPOTHETICAL KINEOCOCCUS RADIOTOLERANS PREDICTED HYDROLASES OR ACYLTRANSFERASES ALPHA
                                           proline rich h/glue
             Kineococcus radiotolerans SRS30216 protein
                                   E value    Best                                Best                   Best                        Best
                                      of    match to                            match to               match to                    match to
            Second                functiona   KOG                    General     PFAM                   SMART                       ACARI
            parent       GO #       l GO    database      E value     class     database    E value    database       E value      database


                         binding
            nucleic acidGO:0003723                           0.029 Function unknown
                                          0.007 Uncharacterized conserved protein                                                putative secreted protein [
                        GO:0005267        0.009 TPR-containing nuclear phosphoprotein that regulates K(+) uptake
            channel or pore class transporter activity                           DUF589        0.061
                                                             0.010 Inorganic ion transport and metabolism                        putative secreted protein [
                        GO:0004003
            hydrolase activity                               0.073 RNA processing and modification, Translation, ribosomal structure and biogenesis
                                          0.007 Ribosome biogenesis protein - Nop56p/Sik1p                                       putative protein [Ixodes sc
                         binding
            nucleic acidGO:0003723                           0.003 Inorganic ion transport and metabolism
                                                                                 Herpes_DNAp_acc
                                                                                               0.044
                                          0.006 TPR-containing nuclear phosphoprotein that regulates K(+) uptake                 fed tick salivary protein 4 [Ixodes s
                        GO:0005267        0.058 Uncharacterized conserved protein
            channel or pore class transporter activity       0.048 Function unknown                                              putative secreted protein [
                         binding
            nucleic acidGO:0003723                           0.003 Inorganic ion transport and metabolism
                                                                                 Herpes_DNAp_acc
                                                                                               0.048
                                          0.004 TPR-containing nuclear phosphoprotein that regulates K(+) uptake                 putative secreted protein [
                         binding
            nucleic acidGO:0003723                           0.003 Inorganic ion transport and metabolism
                                                                                 Herpes_DNAp_acc
                                                                                               0.042
                                          0.006 TPR-containing nuclear phosphoprotein that regulates K(+) uptake                 fed tick salivary protein 4 [Ixodes s
                        GO:0005267        0.009 Uncharacterized conserved protein
            channel or pore class transporter activity       0.061 Function unknown                                              putative secreted protein [
                        GO:0005267        0.098
            channel or pore class transporter activity                                                                           putative secreted salivary
                        GO:0005267        0.009 Uncharacterized conserved protein
            channel or pore class transporter activity                           DUF589
                                                             0.014 Function unknown            0.099                             putative secreted protein [
                        GO:0005267        0.075
            channel or pore class transporter activity                                                                           14 kDa salivary gland prote
                         binding
            nucleic acidGO:0003723                           0.007 Function unknown
                                          0.007 Uncharacterized conserved protein                                                putative secreted protein [
                        GO:0004003
            hydrolase activity                               0.078 RNA processing and modification, Translation, ribosomal structure and biogenesis
                                          0.007 Ribosome biogenesis protein - Nop56p/Sik1p                                       putative protein [Ixodes sc
                        GO:0004003
            hydrolase activity                               0.003 RNA processing and modification, Translation, ribosomal structure and biogenesis
                                          0.015 Ribosome biogenesis protein - Nop56p/Sik1p                                       putative secreted protein [
                         binding
            nucleic acidGO:0003723                           0.005 Inorganic ion transport and metabolism
                                                                                 Herpes_DNAp_acc
                                                                                               0.033
                                          0.009 TPR-containing nuclear phosphoprotein that regulates K(+) uptake                 fed tick salivary protein 4 [Ixodes s
                        GO:0005267        0.007 Uncharacterized conserved protein
            channel or pore class transporter activity                           DUF589
                                                             0.019 Function unknown            0.051                             putative secreted protein [
                                                                                                                                 salivary secreted protein [
                        GO:0005267        0.033 Ribosome biogenesis protein - Nop56p/Sik1p
            channel or pore class transporter activity                                                                           putative protein [Ixodes sc
                                                             0.062 RNA processing and modification, Translation, ribosomal structure and biogenesis
                         binding
            nucleic acidGO:0008248                           0.014 RNA processing and modification, Translation, ribosomal structure and biogenesis
                                                                                 BLVR
                                          0.057 Ribosome biogenesis protein - Nop56p/Sik1p 0.089                                 putative secreted protein [
                         binding
            nucleic acidGO:0003677                           0.059 RNA processing and modification, Translation, ribosomal structurekDa salivary gland prote
                                          0.025 Ribosome biogenesis protein - Nop56p/Sik1p                                       14 and biogenesis
                        GO:0005267        0.063 Ribosome biogenesis protein - Nop56p/Sik1p
            channel or pore class transporter activity                                                                           putative secreted salivary
                                                             0.090 RNA processing and modification, Translation, ribosomal structure and biogenesis
                        GO:0005515
            protein binding                                  0.037 Transcription, Replication,                                    structure and dynamics
                                          0.034 Nucleosome-binding factor SPN, POB3 subunit recombination and repair, Chromatinputative protein [Ixodes sc
                        GO:0005515
            protein binding                                  0.027 Inorganic ion transport and metabolism
                                          0.033 TPR-containing nuclear phosphoprotein that regulates K(+) uptake                 putative secreted protein [
                        GO:0005515
            protein binding                                  0.035 Transcription, Replication,                                    structure and dynamics
                                          0.034 Nucleosome-binding factor SPN, POB3 subunit recombination and repair, Chromatinputative secreted protein [
                        GO:0005515
            protein binding                                  0.065 Transcription, Replication,                                    structure and dynamics
                                          0.015 Nucleosome-binding factor SPN, POB3 subunit recombination and repair, Chromatinputative secreted protein [
                        GO:0003714        0.026 Nucleosome-binding factor SPN, POB3 subunit recombination and repair, Chromatinputative secreted protein [
            transcription cofactor activity                  0.018 Transcription, Replication,                                    structure and dynamics
                        GO:0003714        0.026 Nucleosome-binding factor SPN, POB3 subunit recombination and repair, Chromatinputative protein [Ixodes sc
            transcription cofactor activity                  0.024 Transcription, Replication,                                    structure and dynamics
                        GO:0005554
molecular_function unknown                                   0.014 Inorganic ion transport and metabolism
                                          0.015 TPR-containing nuclear phosphoprotein that regulates K(+) uptake                 putative secreted protein [
                        GO:0005554
molecular_function unknown                                   0.025 Transcription, Replication,                                    structure and dynamics
                                          0.015 Nucleosome-binding factor SPN, POB3 subunit recombination and repair, Chromatinputative secreted protein [
                        GO:0005554
molecular_function unknown                                   0.035 RNA processing and modification, Translation, ribosomal structure and biogenesis
                                          0.057 Ribosome biogenesis protein - Nop56p/Sik1p                                       putative salivary protein [
                        GO:0005515
            protein binding                                  0.035 Transcription, Replication,                                    structure and dynamics
                                          0.034 Nucleosome-binding factor SPN, POB3 subunit recombination and repair, Chromatinputative secreted protein [
                        GO:0005515
            protein binding                                  0.038 Transcription, Replication,                                    structure and dynamics
                                          0.026 Nucleosome-binding factor SPN, POB3 subunit recombination and repair, Chromatinputative secreted protein [
                        GO:0005554
molecular_function unknown                                   0.020 Transcription, Replication,                                    structure and dynamics
                                            0.02 Nucleosome-binding factor SPN, POB3 subunit recombination and repair, Chromatinputative secreted protein [
                        GO:0005554
molecular_function unknown                                   0.038 Transcription, Replication,                                    structure and dynamics
                                          0.015 Nucleosome-binding factor SPN, POB3 subunit recombination and repair, Chromatinputative secreted protein [
                        GO:0003714        0.034 Nucleosome-binding factor SPN, POB3 subunit recombination and repair, Chromatinputative secreted protein [
            transcription cofactor activity                  0.020 Transcription, Replication,                                    structure and dynamics
                        GO:0005554
molecular_function unknown                                   0.011 Inorganic ion transport and metabolism
                                          0.015 TPR-containing nuclear phosphoprotein that regulates K(+) uptake                 putative secreted protein [
transporter activity    GO:0005215                           0.013 Energy production and conversion
                                          0.003 Dihydrolipoamide succinyltransferase (2-oxoglutarate dehydrogenase, E2 subunit)  BTSP-11 [Ixodes pacificus]
                        GO:0005267        0.007 Uncharacterized conserved protein
            channel or pore class transporter activity       0.036 Function unknown                                              putative secreted protein [
                        GO:0005515
            protein binding               0.089                                                                                  BTSP-11 [Ixodes pacificus]
                        GO:0015276        0.074 Thyroid      0.024 Transcription
            channel or pore class transporter activity hormone receptor-associated protein complex, subunit TRAP230              BTSP-11 [Ixodes pacificus]
                        GO:0003700
            transcription factor activity 0.043                                                                                  BTSP-11 [Ixodes pacificus]
                        GO:0005267        0.002 Ribosome biogenesis protein - Nop58p/Nop5p
            channel or pore class transporter activity                                                                           putative secreted protein [
                                                             0.064 RNA processing and modification, Translation, ribosomal structure and biogenesis

                                                                                                                                   putative protein [Ixodes sc
                                                                                                                                   putative protein [Ixodes sc
                                                                                                                        putative anticoagulant Salp
                                                                                                                        putative anticoagulant Salp
                                                                                                                        putative anticoagulant Salp
                                                                                                                        putative anticoagulant Salp
                                                                                                                        putative anticoagulant Salp
                                                                                                                        putative anticoagulant Salp
                                                                                                                        putative anticoagulant Salp
                                                                                                                        putative anticoagulant Salp
                                                                                                                        putative anticoagulant Salp
                                                                                                                        putative salivary secreted peptide [I
                                                                                                                        putative secreted salivary



                                                                                                                       Salp10 [Ixodes scapularis]       137
                                                                                                                       putative secreted protein [
                                                                                                                       putative secreted protein [
                                                  0.080 Signal transduction mechanisms
                                    Epidermal growth factor receptor EGFR and related tyrosine kinases                 Salp10 [Ixodes scapularis]       209
                                                                                              KU               0.018   putative secreted protein [
          GO:0004866
enzyme inhibitor activity 0.0004                                                              KU               0.005   putative secreted protein [
          GO:0004866
enzyme inhibitor activity 0.0009                                                              KU               0.006   putative secreted protein [
          GO:0004866
enzyme inhibitor activity  0.026                                                                                       fed tick salivary protein 2 [Ixodes s
                                                                       RNase_U2 0.075                                  putative secreted protein [
                                                                       RNase_U2 0.069                                  putative secreted protein [
                                                                                              KU               0.011   putative secreted protein [
                                                                                              KU               0.082   putative secreted protein [
            GO:0004867
enzyme inhibitor activity 1E-12                  4E-008 Posttranslational
                                                                       Kunitz_BPTI 3E-013 KU                  6E-016
                                    Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones putative secreted protease
            GO:0004867
enzyme inhibitor activity 3E-12                  1E-007 Posttranslational
                                                                       Kunitz_BPTI 2E-013 KU                  8E-017
                                    Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones putative secreted protease
            GO:0005515
protein binding           0.036                   0.025 Posttranslational
                                                                       Kunitz_BPTI 2E-004 KU                  1E-005
                                    Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones putative secreted protein [
            GO:0005515
protein binding           0.081                   0.044 Posttranslational
                                                                       Kunitz_BPTI 0.005 KU                   7E-004
                                    Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones putative secreted protein [
            GO:0004866
enzyme inhibitor activity 0.003                                        Kunitz_BPTI 0.008 KU                   3E-004   putative secreted protein [
            GO:0005515 0.0008
protein binding                                                        Kunitz_BPTI 5E-005 KU                  7E-006   putative secreted protein [
            GO:0005515
protein binding           0.007                                        Kunitz_BPTI 0.002 KU                   4E-005   putative secreted protein [
            GO:0004866
enzyme inhibitor activity 0.007                                        Kunitz_BPTI 0.003 KU                   2E-005   putative secreted protein [
                                                                                              KU               0.045   putative secreted protein [
            GO:0005515
protein binding             0.002                7E-004 Posttranslational
                                                                       Kunitz_BPTI 2E-004 KU                  4E-006
                                    Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones putative secreted protein [
            GO:0005515
protein binding             0.001                 0.003 Posttranslational
                                                                       Kunitz_BPTI 7E-005 KU                  5E-007
                                    Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones putative secreted protein [
            GO:0005515
protein binding             0.001                 0.003 Posttranslational
                                                                       Kunitz_BPTI 5E-005 KU                  5E-007
                                    Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones putative secreted protein [
            GO:0004866
enzyme inhibitor activity   0.004                                      Kunitz_BPTI 0.034 KU                    0.004   putative secreted protein [
            GO:0005515
protein binding             0.002                                      Kunitz_BPTI 0.001 KU                   2E-005   putative secreted protein [
            GO:0004867
enzyme inhibitor activity   0.019                                      Kunitz_BPTI 0.004 KU                   2E-004   putative secreted protein [
                                                                       Kunitz_BPTI 0.005 KU                   1E-004   putative secreted protein [
                                                                       Kunitz_BPTI 0.006 KU                   1E-004   putative secreted protein [
            GO:0004866
enzyme inhibitor activity 0.0002                  0.036 Posttranslational
                                                                       Kunitz_BPTI 1E-004 KU                  6E-006
                                    Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones putative secreted protein [
            GO:0004866
enzyme inhibitor activity 0.0002                  0.009 Posttranslational
                                                                       Kunitz_BPTI 7E-004 KU                  1E-005
                                    Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones KUN-6 [Ixodes pacificus]
            GO:0004866
enzyme inhibitor activity 0.00004                 0.090 Posttranslational
                                                                       Kunitz_BPTI 3E-004 KU                  7E-006
                                    Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones putative secreted protein [
            GO:0004867
enzyme inhibitor activity   0.015                 0.012 Posttranslational
                                                                       Kunitz_BPTI 0.001 KU                   1E-005
                                    Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones putative secreted protein [
            GO:0005515
protein binding             0.021                 0.002 Posttranslational
                                                                       Kunitz_BPTI 5E-004 KU                  2E-006
                                    Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones putative secreted protein [
                                                                                              KU               0.004   putative secreted protein [
                                                                       Kunitz_BPTI 0.074 KU                    0.001   putative secreted protein [
                                                                       Kunitz_BPTI 0.067 KU                    0.002   putative secreted protein [
                                                                       DUF713       0.052 KU                   0.009   putative secreted protein [
                                                                                              ACR              0.075   putative 8.4 kDa secreted p
                                                                                                                       putative 8.4 kDa secreted p
                                                                                                                       putative 8.4 kDa secreted p
                                                                                                                       putative secreted protein [
                                                                                              DM11             0.070   putative secreted protein [
                                                                                                                       putative secreted protein [
                                                  0.035 Secondary metabolites biosynthesis, transport and catabolism putative secreted protein [
                                    Multidrug/pheromone exporter, ABC superfamily
                                                  0.047 Secondary metabolites biosynthesis, transport and catabolism putative secreted protein [
                                    Multidrug/pheromone exporter, ABC superfamily
                                                                                                                       putative salivary secreted
            GO:0005515
protein binding             0.002                                      Kunitz_BPTI 0.003 KU                   4E-004   putative secreted salivary gland pep
            GO:0005515
protein binding             0.001                                      Kunitz_BPTI 0.011 KU                   6E-004   putative secreted salivary gland pep
            GO:0005515
protein binding             0.004                 0.036 Posttranslational
                                                                       Kunitz_BPTI 0.002 KU                   3E-004
                                    Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones putative secreted salivary gland pep
                                                         0.048 Amino acid Kunitz_BPTI 0.019 KU Posttranslational modification, protein turnover, chaperones
                                                                              transport and metabolism,
                                           Serine carboxypeptidases (lysosomal cathepsin A)                           0.003   putative secreted protein [
           ion binding GO:0008270                        0.057 Amino acid Kunitz_BPTI 0.048 KU Posttranslational modification, protein turnover, chaperones
                                                                              transport and metabolism,
                                     0.057 Serine carboxypeptidases (lysosomal cathepsin A)                           0.003   putative secreted protein [
                                                                              Kunitz_BPTI 0.003 KU                   4E-005   putative secreted protein [
                                                                              Kunitz_BPTI 0.002 KU                   7E-005   putative secreted protein [
                       GO:0004866
           enzyme inhibitor activity 0.002                                    Kunitz_BPTI 0.002 KU                   4E-005   putative secreted protein [
                       GO:0004866
           enzyme inhibitor activity                     0.060 Posttranslational
                                                                              Kunitz_BPTI 0.003 KU                    0.001
                                     0.015 Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones putative secreted protein [
                        binding
           nucleic acidGO:0003677 0.0005                                      Kunitz_BPTI 0.002 KU                   2E-005   putative secreted protease
                                                                                                                              putative 8.4 kDa secreted p
                                                                                                                              putative secreted salivary gland pep
                                                                                                     MCM              0.033   putative secreted protein [

                        GO:0004866
           enzyme inhibitor activity 5E-17                      6E-006 Posttranslational
                                                                                      Kunitz_BPTI 3E-010 KU                 4E-013
                                                  Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones   KUN-5 [Ixodes pacificus]
                        GO:0019855 0.0009
           auxiliary transport protein activity                                                             KU               0.022     putative secreted protein [
                        GO:0005515 3E-15
           protein binding                                       0.006 Posttranslational modification, protein turnover,
                                                                                      Kunitz_BPTI 6E-007 KU                 1E-009
                                                  Serine proteinase inhibitor (KU family) with thrombospondin repeats chaperones       ixolaris-1 [Ixodes pacificus]
                        GO:0005515 2E-16
           protein binding                                      3E-006 Posttranslational
                                                                                      Kunitz_BPTI 1E-010 KU                 2E-013
                                                  Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones   ixolaris [Ixodes scapularis]    358 e
                        GO:0004866
           enzyme inhibitor activity 2E-14                      5E-005 Posttranslational
                                                                                      Kunitz_BPTI 3E-010 KU                 7E-013
                                                  Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones   putative secreted protein [
                        GO:0019855 8E-10
           auxiliary transport protein activity                  0.003 Posttranslational
                                                                                      Kunitz_BPTI 9E-008 KU                 2E-009
                                                  Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones   ixolaris-2 [Ixodes pacificus]
                        GO:0004866
           enzyme inhibitor activity 3E-11                       0.003 Posttranslational
                                                                                      Kunitz_BPTI 2E-007 KU                 5E-008
                                                  Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones   ixolaris-2 [Ixodes pacificus]
                        GO:0004866
           enzyme inhibitor activity 8E-10                                            Kunitz_BPTI 9E-007 KU                 1E-008     ixolaris-2 [Ixodes pacificus]
                        GO:0005515 4E-09
           protein binding                                       0.007 Replication,Kunitz_BPTI component
                                                                                       recombination and KU
                                                  Nucleotide excision repair factor NEF2, RAD23 2E-007repair                4E-009     ixolaris-2 [Ixodes pacificus]
                        GO:0005515 4E-10
           protein binding                                       0.020     protein TAU
                                                  Microtubule-associatedCytoskeleton  Kunitz_BPTI 9E-008 KU                 2E-009     ixolaris-2 [Ixodes pacificus]
                        GO:0019855       0.006
           auxiliary transport protein activity   Actin regulatory proteinSignal transduction mechanisms, Cytoskeleton
                                                                 0.047                Kunitz_BPTI 0.068 KU
                                                                           (Wiskott-Aldrich syndrome protein)                0.029     putative secreted protein [

                       GO:0004867
           enzyme inhibitor activity    4E-07                                    Kunitz_BPTI 0.056 KU                   8E-005         putative secreted protein [
                       GO:0004866
           enzyme inhibitor activity                       5E-004 Posttranslational
                                                                                 Kunitz_BPTI 3E-008 KU                  6E-010
                                        8E-09 Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones       boophilin [Boophilus microplus]
                       GO:0005515
           protein binding              2E-07                                    Kunitz_BPTI 0.031 KU                   3E-004         putative secreted protein [
                       GO:0004866
           enzyme inhibitor activity                        0.056 Posttranslational
                                                                                 Kunitz_BPTI 5E-004 KU                  7E-007
                                        1E-10 Serine proteinase inhibitor (KU family) modification, protein turnover, chaperones       putative secreted protein [
                       GO:0004867
           enzyme inhibitor activity    1E-09                                                           KU              6E-004         KUN-4 [Ixodes pacificus]
                       GO:0004867
           enzyme inhibitor activity    3E-10                                    Kunitz_BPTI 0.024 KU                   2E-005         putative secreted protein [
                       GO:0004867
           enzyme inhibitor activity    8E-09                                    Kunitz_BPTI 0.005 KU                   3E-004         putative secreted protein [
                       GO:0004867
           enzyme inhibitor activity    2E-08                                    Kunitz_BPTI 0.018 KU                   6E-004         putative secreted protein [

                        GO:0005200 0.00002 Dosage compensation Transcription
            structural constituent of cytoskeleton              0.034   complex, subunit MLE                                           putative secreted salivary gland pep
                        GO:0005529
            carbohydrate binding                                0.018
                                          0.013 AAA+-type ATPase Posttranslational modification, protein turnover, chaperones          putative secreted protein [
                        GO:0042302        0.017
            structural constituent of cuticle                                                                                          putative secreted protein [
                        GO:0003700                              0.009 Signal transduction mechanisms
            transcription factor activity 0.033 Inositol 1,4,5-trisphosphate receptor                                                  putative secreted protein [
                        GO:0005529
            carbohydrate binding          0.001                                    DUF390       0.046                                  putative secreted protein [
                        GO:0042302        0.001 Inositol 1,4,5-trisphosphate receptor
            structural constituent of cuticle                   0.004 Signal transduction mechanisms                                   putative secreted protein [
                        GO:0030528
transcription regulator activity            0.01                                                                                       putative secreted protein [
                        GO:0005201        0.005
            extracellular matrix structural constituent                                                                                putative secreted protein [
                        GO:0005529
            carbohydrate binding                                0.049
                                          0.013 AAA+-type ATPase Posttranslational modification, protein turnover, chaperones          putative secreted protein [
                        GO:0042302        0.003
            structural constituent of cuticle                                                                                          putative secreted protein [
                        GO:0030020        0.002
            extracellular matrix structural constituent                                                                                CLSP-8 [Ixodes pacificus]
                        GO:0004295
            hydrolase activity                                  0.041 Replication,CD2
                                                                                    recombination and repair
                                          0.005 DNA replication licensing factor, MCM4 component0.045                                  CLSP-2 [Ixodes pacificus]
                        GO:0042302        0.001 AAA+-type ATPase Posttranslational modification, protein turnover, chaperones
            structural constituent of cuticle                   0.017              CD2          0.017                                  CLSP-2 [Ixodes pacificus]
                        GO:0030528
transcription regulator activity          0.057                                                                                        putative secreted protein [
                        GO:0003700
            transcription factor activity 0.043                                                                                        putative secreted protein [
                        GO:0003700
            transcription factor activity 0.015                                                                                        putative secreted protein [
                         activity
            transferase GO:0004674        0.029                                                                                        CLSP-2 [Ixodes pacificus]
                        GO:0005554 6E-07 RhoA GTPase effector Signal transduction mechanisms, Cytoskeleton
molecular_function unknown                                    3E-004 DIA/DiaphanousCD2         1E-005                                  CLSP-1 [Ixodes pacificus]
                        GO:0042302        0.086 Inositol 1,4,5-trisphosphate receptor
            structural constituent of cuticle                   0.012 Signal transduction mechanisms                                   putative secreted protein [
                        GO:0005201        0.006
            extracellular matrix structural constituent                                                                                putative secreted protein [
                        GO:0005198
structural molecule activity                                    0.072 Signal transduction mechanisms
                                          0.017 Inositol 1,4,5-trisphosphate receptor                                                  putative secreted protein [
                        GO:0042302 0.0002
            structural constituent of cuticle                                                                                          CLSP-5 [Ixodes pacificus]
                                                                                                                                       CLSP-11 [Ixodes pacificus]
                       GO:0005554 0.00004 Oligophrenin-1 and related Rho GTPase-activating proteins
molecular_function unknown                                                 CD2         6E-004
                                                        0.015 Signal transduction mechanisms                                           CLSP-1 [Ixodes pacificus]
                       GO:0005198 0.00002 RhoA GTPase effector Signal transduction mechanisms, Cytoskeleton
structural molecule activity                                               CD2
                                                       3E-004 DIA/Diaphanous           8E-004                                          CLSP-8 [Ixodes pacificus]
                                                                                                                                       putative secreted protein [
                        GO:0030528
transcription regulator activity                          0.037
                                        0.025 AAA+-type ATPase          Posttranslational modification, protein turnover, chaperones   CLSP-2 [Ixodes pacificus]
                                                                                                                                       putative secreted protein [
                       GO:0005201 0.0002 RhoA                0.050     DIA/Diaphanous
                                                                                   CobT        0.069
           extracellular matrix structural constituent GTPase effector Signal transduction mechanisms, Cytoskeleton                    CLSP-2 [Ixodes pacificus]
                       GO:0005515
           protein binding               0.074                                                                                         putative secreted protein [
                                                                                                                                   notch-like protein [Boophilus micropl
                        GO:0005515
            protein binding               0.074                                                                                    putative secreted protein [
                        GO:0042302        0.003
            structural constituent of cuticle                                                                                      CLSP-2 [Ixodes pacificus]
                        GO:0005200 1E-14 Dosage compensation Transcription
            structural constituent of cytoskeleton                       API5
                                                   3E-012 complex, subunit MLE 2E-005                                              NPL-2 [Ixodes pacificus]
                                                                                                                                   CLSP-9 [Ixodes pacificus]
                                                                   0.016 Signal transduction mechanisms
                                                   Inositol 1,4,5-trisphosphate receptor                                           putative secreted protein [
                        GO:0042302        0.004
            structural constituent of cuticle                      0.086 Signal transduction mechanisms
                                                                                      Menin
                                                   Inositol 1,4,5-trisphosphate receptor         0.049                             putative secreted protein [
                        GO:0042802
            protein binding               0.096                    0.007
                                                   AAA+-type ATPase Posttranslational modification, protein turnover, chaperones   putative secreted protein [
                        GO:0042302        0.033
            structural constituent of cuticle                      0.018
                                                   AAA+-type ATPase Posttranslational modification, protein turnover, chaperones   putative secreted protein [
                        GO:0042302        0.001
            structural constituent of cuticle                      0.004 Signal transduction mechanisms
                                                   Inositol 1,4,5-trisphosphate receptor                                           putative protein [Ixodes sc
                        GO:0005515
            protein binding               0.029                    0.047 Signal transduction mechanisms
                                                   Inositol 1,4,5-trisphosphate receptor                                           putative secreted protein [
                        GO:0042302        0.002
            structural constituent of cuticle                      0.016 Signal transduction mechanisms
                                                   Inositol 1,4,5-trisphosphate receptor                                           putative secreted protein [
                        GO:0042302        0.001
            structural constituent of cuticle                      0.010 Signal transduction mechanisms
                                                   Inositol 1,4,5-trisphosphate receptor                                           putative secreted protein [
                        GO:0042302        0.002
            structural constituent of cuticle                      0.019 Signal transduction mechanisms
                                                   Inositol 1,4,5-trisphosphate receptor                                           putative secreted protein [
                        GO:0005198 0.0001
structural molecule activity                                       0.039    DIA/Diaphanous
                                                   RhoA GTPase effector Signal transduction mechanisms, Cytoskeleton               putative secreted protein [
                        GO:0042302          0.01
            structural constituent of cuticle                                                                                      putative secreted protein [
                        GO:0005198 0.00006
structural molecule activity                                                                                                       putative secreted protein [
                        GO:0005529 0.00007
            carbohydrate binding                                                      Menin      0.054                             putative secreted protein [
                                                                   0.016 Signal transduction mechanisms
                                                   Inositol 1,4,5-trisphosphate receptor                                           putative secreted protein [

            ion binding GO:0005509        0.085                                                                                    putative 18.7 kDa secreted
                        GO:0005201        0.064
            extracellular matrix structural constituent                                                                            putative 18.7 kDa secreted
                        GO:0005515
            protein binding               0.037                                                           DUF2          0.010      putative 18.7 kDa secreted
                                                                                                                                   putative 18.7 kDa secreted
                       GO:0005041
            receptor activity            0.017                                                                                     18_2 putative 19 kDa secreted prote
                                                                                                                                   putative 18.7 kDa secreted

                                                                                                                                   putative secreted peptide of 6.3 kDa
                                                                                                                                   putative secreted peptide of 4.99 kD
                         binding
            nucleic acidGO:0003697       0.017                                                                                     holocyclotoxin-1 [Ixodes holocyclus]
                                                                                                                                   putative secreted peptide of 4.99 kD
                                                                                                                                   putative secreted peptide of 4.99 kD
                                                                                                                                   putative secreted peptide of 4.99 kD
                                                                0.059 Function unknown
                                                   Uncharacterized conserved protein                                               putative secreted peptide of 4.99 kD
                                                                                                                                   putative 5.3 kDa secreted p
                                                                                                                                   putative 5.3 kDa secreted p
                                                                                                                                   putative secreted peptide of 4.3 kDa
                                                                                                                                   putative 5.3 kDa secreted p
                                                                                   DUF1304      0.035                              putative 5.3 kDa secreted p
                                                                                   DUF1423      0.021                              putative 5.3 kDa secreted p
                                                                                                                                   putative 5.3 kDa secreted p
                                                                                                                                   putative secreted peptide of 4.3 kDa
                        GO:0005112
            receptor binding             0.096                                                                                     putative secreted peptide of 4.3 kDa
                                                                                                                                   putative secreted peptide of 4.3 kDa

                                                                                                                                   putative secreted salivary peptide of
                                                                                                                                   putative secreted salivary gland pep
                                                                                                                                   putative secreted salivary peptide of
                                                                                                                                   putative 9.4 kDa secreted p
                                                                                                                                   putative 9.4 kDa secreted p
                                                                                                                                   putative 7 kDa secreted pro
                                                                                                                                   putative secreted salivary peptide of
                                                                                                                                   putative secreted salivary peptide of
                                                                                                                                   putative secreted salivary gland pep
                                                                                                                                   putative secreted salivary gland pep
                                                                                                                                   putative secreted salivary gland pep
                                                                                   NSP11        0.016                              putative 9.4 kDa secreted p
                                                                                                                                   putative 7 kDa secreted pro

                        GO:0005178
            receptor binding                                3E-011 Posttranslational modification, protein
                                                                                  Reprolysin 2E-014 ZnMc               0.053
                                         3E-07 Disintegrin metalloproteinases with thrombospondin repeats turnover, chaperones     truncated secreted metallop
                        activity
            transferase GO:0008318                          2E-012 Posttranslational modification, protein
                                                                                  Reprolysin 1E-011 ACR               8E-004
                                         3E-08 Disintegrin metalloproteinases with thrombospondin repeats turnover, chaperones     salivary gland metalloprotease [Ixod
                        activity
            transferase GO:0008318                          2E-012 Posttranslational modification, protein
                                                                                  Reprolysin 1E-011 ACR               8E-004
                                         3E-08 Disintegrin metalloproteinases with thrombospondin repeats turnover, chaperones     salivary gland metalloprotease [Ixod
                      GO:0008237
           hydrolase activity                                8E-011 Posttranslational modification, protein turnover, chaperones
                                                                                  Reprolysin 4E-012 ACR                  0.003
                                       5E-09 Meltrins, fertilins and related Zn-dependent metalloproteinases of the ADAMs family   truncated secreted metallop

                                                                                                                                   putative salivary secreted peptide [I
                                                                                                                                   putative salivary secreted peptide [I
                                                                                                                                   putative salivary secreted peptide [I
                     GO:0008047
           enzyme activator activity                      0.039     E3 ubiquitin ligase
                                       0.026 RING-finger-containingPosttranslational modification, protein turnover, chaperones    putative salivary secreted peptide [I


                       GO:0005178
           receptor binding            0.045                                                                                       putative salivary secreted peptide [I



                                                                                                                                    midgut cysteine proteinase 5 [Rhipic
                                                                                                                                    16 kDa salivary gland prote
                                                                                                                                    16 kDa salivary gland prote
                        GO:0008237
            hydrolase activity                                   0.004 Posttranslational modification, protein turnover, chaperones
                                                                                                           ACR             1E-005
                                          0.003 Meltrins, fertilins and related Zn-dependent metalloproteinases of the ADAMs family putative secreted protein [
                                                                                                                                    16 kDa salivary gland prote
                                                                                                                                    TEBP=tick embryo basic protein {N-
                                                                                                                                    16 kDa salivary gland prote
                                                                                                                                    16 kDa salivary gland prote
                                                                 0.027 Posttranslational modification, protein turnover, chaperones
                                                Meltrins, fertilins and related Zn-dependent metalloproteinases of the ADAMs family 15 kDa salivary gland prote
                        GO:0008237
            hydrolase activity            0.058                                                            ACR              0.009   thrombospondin [Ixodes scap
                                                                                                                                    thrombospondin [Ixodes scap
                         activity
            transferase GO:0008318                               0.067 Extracellular structures            ACR              0.003   THR2 [Ixodes pacificus]
                                           0.02 Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17) and related metalloproteases
                         activity
            transferase GO:0008318                               0.097 Posttranslational modification, protein turnover, chaperones
                                          0.011 Meltrins, fertilins and related Zn-dependent metalloproteinases of the ADAMs family putative secreted protein [
                                                                                                                                    15 kDa salivary gland prote
                         activity
            transferase GO:0008318                               0.065 Posttranslational modification, protein turnover, chaperones
                                                                                                           ACR             4E-004
                                          0.056 Meltrins, fertilins and related Zn-dependent metalloproteinases of the ADAMs family THR2 [Ixodes pacificus]
                                                                                                                                    16 kDa salivary gland prote
                         activity
            transferase GO:0008318                               0.022 Posttranslational modification, protein turnover, chaperones
                                                                                                           ACR             5E-004
                                          0.009 Meltrins, fertilins and related Zn-dependent metalloproteinases of the ADAMs family putative secreted protein [
                                                                                                           ACR              0.064   putative secreted protein [
                        GO:0005515
            protein binding               0.034                                                                                     salivary gland 16 kD protei
                                                                                                                                    16 kDa salivary gland prote
                                                                                                                                    16 kDa salivary gland prote
                                                                                                                                    paramyosin [Sarcoptes scabiei] 23
                                                                                                                                    16 kDa salivary gland prote
                                                                                                           ACR              0.032   putative secreted salivary gland pep
                                                                                                           ACR              0.094   putative secreted salivary gland pep
                        GO:0004871
signal transducer activity                0.057                                                                                     15 kDa salivary gland prote
                                                                                                                                    putative peptide 11.3 kDa [Ixodes pa
                                                                                                                                    putative secreted salivary gland pep
                        GO:0005178
            receptor binding              0.044                                                                                     putative secreted salivary gland pep
                        GO:0005201        0.096
            extracellular matrix structural constituent                                                    ACR              0.018   putative secreted protein [
                                                                                                                                    putative secreted salivary gland pep
                                                                 0.021 Translation, subunit
                                                Phenylalanyl-tRNA synthetase betaribosomal structure and biogenesis                 putative secreted salivary gland pep
                                                                                                                                    putative secreted salivary gland pep
                        GO:0005178
            receptor binding                                     0.003 Posttranslational modification, protein turnover, chaperones
                                                                                                           ACR             3E-005
                                          0.001 Meltrins, fertilins and related Zn-dependent metalloproteinases of the ADAMs family putative secreted protein [
                         activity
            transferase GO:0008318        0.015                                                            ACR              0.002   putative secreted protein [
                                                                                                                                    16 kDa salivary gland prote
                                                                 0.097    protein
                                                Predicted DNA-bindingTranscription                                                  15 kDa salivary gland prote
                                                                                                           ACR              0.007   thrombospondin [Ixodes scap

                                                                                                                                   putative 22.5 kDa secreted
                                                                                His_binding 1E-006                                 male-specific histamine-binding saliv
                                                                                                                                   26 kDa salivary gland prote
                                                                                                                                   lipocalin-like protein [Boophilus mic
                                                                                                                                   lipocalin-like protein [Boophilus mic
                                                                                His_binding 0.018                                  putative protein [Ixodes sc
                                                                                                                                   truncated histamine binding protein [
                                                                                His_binding 0.016                                  25 kDa salivary gland prote
                                                                                His_binding 0.045                                  histamine binding protein [
                                                                                                                                   histamine binding protein [
                                                           0.064 General        His_binding 0.003
                                               WD40 repeat-containing proteinfunction prediction only                              histamine binding protein [
                                                                                                                                   truncated histamine binding protein [
                                                                                                                              putative 22.7 kDa secreted
                                                                                                                              26 kDa salivary gland prote
                                                                                                                              26 kDa salivary gland prote
                                                                                                     PLAc            0.011    lipocalin-like protein [Boophilus mic
                                                                                                                              putative 22.5 kDa secreted
                                                                                                                              putative secreted histamine binding
                                                                                                                              26 kDa salivary gland prote
                                                                                                                              26 kDa salivary gland prote
                                                                                                                              truncated histamine binding protein [
                                                                                                                              26 kDa salivary gland prote
                                                                                                                              putative 22.5 kDa secreted
                                                                                                                              18_3 putative 19 kDa secreted prote
                                                                                                                              26 kDa salivary gland prote
                                                                                                                              putative 22.7 kDa secreted
                                                                                                                              putative 22.7 kDa secreted
                                                                                                                              putative protein [Ixodes sc
                                                                                                                              18_3 putative 19 kDa secreted prote
                                                           0.051 General       His_binding 0.002
                                              WD40 repeat-containing proteinfunction prediction only                          histamine binding protein [
                                                                                                                              putative secreted protein [
                                                                               His_binding 0.098                              putative secreted protein [
                                                                               His_binding 0.020                              putative protein [Ixodes sc
                                                                                                                              putative 22.7 kDa secreted
                                                                               His_binding 2E-004                             male-specific histamine-binding saliv
                                                                                                                              truncated histamine binding protein [
                                                                               His_binding 5E-006                             putative secreted histamine binding
                                                                               His_binding 1E-005                             lipocalin-like protein [Boophilus mic
                                                                                                     Glyco_10        0.040    truncated histamine binding protein [
                      GO:0003713        0.064
          transcription cofactor activity                                                                                     putative secreted histamine binding
                                                                                                                              putative secreted salivary gland pep
                      GO:0005201        0.063
          extracellular matrix structural constituent                          His_binding 0.003                              putative secreted salivary gland pep
                                                                                                                              putative 22.7 kDa secreted
                                                                                                                              putative 22.5 kDa secreted
                                                           0.083 Carbohydrate transport 2                                     putative secreted protein [
                                              Acetylglucosaminyltransferase EXT2/exostosinand metabolism, Cell wall/membrane/envelope biogenesis, Extracellular stru
                                                                                                                              putative protein [Ixodes sc
                                                                               His_binding 5E-005                             putative secreted histamine
                                                                               His_binding 2E-004                             putative secreted histamine
                                                                                                                              25 kDa salivary gland prote
                                                                                                     Zn_pept         0.098    26 kDa salivary gland prote
                                                                                                                              25 kDa salivary gland prote
                                                                                                                              17 kDa salivary gland prote
                                                           0.069 General function prediction only
                                              NAD dependent epimerase          His_binding 7E-004                             histamine binding protein [

                         binding                   3E-010 complex, subunit MLE 1E-005
                                                                         API5
            nucleic acidGO:0003723 3E-11 Dosage compensation Transcription                                                     putative secreted salivary gland pep
                        GO:0005200 3E-16 Dosage compensation Transcription
            structural constituent of cytoskeleton 5E-009 complex, subunit MLE                                                 putative secreted salivary gland pep
                        GO:0005198 1E-13 Dosage compensation Transcription
structural molecule activity                                             AKAP95
                                                   2E-010 complex, subunit MLE 0.017                                           putative secreted salivary gland pep
                        GO:0005200 2E-09 Dosage compensation Transcription
            structural constituent of cytoskeleton                       API5
                                                   5E-006 complex, subunit MLE 4E-005                                          NPL-1 [Ixodes pacificus]



                                                                             Defensin_2 3E-005      Knot1           0.075      putative secreted salivary gland pep

                                                        0.060 Lipid transport and acid transporter
                                           Very long-chain acyl-CoA synthetase/fatty metabolism                                putative salivary secreted peptide wi
                                                                                                                               putative salivary secreted peptide wi



                     GO:0004602 5E-42 Glutathione peroxidasePosttranslational modification, protein turnover, chaperones
          oxidoreductase activity                     4E-042               GSHPx          4E-031                               truncated glutathione peroxidase [Ixo
                     GO:0004601 8E-75 Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes
          oxidoreductase activity                                          AhpC-TSA 7E-037
                                                      5E-091 Posttranslational modification, protein turnover, chaperones      glutathione peroxidase [Ixo
                     GO:0008379                       3E-093 Posttranslational modification, protein turnover, chaperones
                                                                           AhpC-TSA 9E-047
          oxidoreductase activity 1E-105 Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes         thioredoxin peroxidase [Ixodes ricinu
                     GO:0008785 4E-85 Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes
          oxidoreductase activity                                          AhpC-TSA 8E-049
                                                      3E-093 Posttranslational modification, protein turnover, chaperones      thioredoxin peroxidase [Ixodes ricinu
                     GO:0008785 6E-84 Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes
          oxidoreductase activity                                          AhpC-TSA 6E-050
                                                      3E-092 Posttranslational modification, protein turnover, chaperones      thioredoxin peroxidase [Ixodes ricinu

                      GO:0008430
           selenium binding                           2E-034
                                    5E-32 Selenoprotein                     Pox_int_trans 0.008
                                                                 General function prediction only                              heat shock protein 82 [Platynothrus
                      GO:0005554
molecular_function unknown                            8E-005
                                    3E-15 Selenoprotein          General function prediction only                              paramyosin [Sarcoptes scabiei] 23
                                                              T
                                                Selenoprotein 0.032     General function prediction only                           glutathione S-transferase [

                                                                                                                                   20 kDa salivary gland prote
                                                                                                                                   20 kDa salivary gland prote
                                                                                                                                   20 kDa salivary gland prote
                                                                                   Transaldolase0.088                              anticomplement protein [Ixod
                                                                                                                                   anticomplement protein [Ixod
                                                                                                                                   Salp9 [Ixodes scapularis]
                                                                                   Transaldolase0.047                              20 kDa salivary gland prote

                                                                                                                                   putative secreted salivary gland pep
                                                                                                                                   putative immunoglobulin-binding pro
                                                                                                                                   putative immunoglobulin-binding pro
                                                                                                                                   putative secreted salivary gland pep
                     GO:0005006
          receptor activity             0.011                                                                                      putative 10.2 kDa secreted
                     GO:0005006
          receptor activity             0.019                                                                                      putative 10.2 kDa secreted
                                                                                                                                   putative secreted salivary gland pep
                                                                                               0.031
                                                                                   Opiods_neuropep                                 putative secreted salivary gland pep
                                                                                                                                   putative secreted salivary gland pep
                                                                                                                                   putative secreted salivary gland pep
                                                              0.041 Posttranslational modification, protein turnover, chaperones
                                                Putative ubiquitin-specific protease                                               putative secreted salivary gland pep
                                                                                                                                   putative secreted salivary gland pep
                                                                                   Pox_RNA_pol0.019                                putative 10.2 kDa secreted
                                                                                                                                   putative 10.2 kDa secreted
                                                                                                                                   putative 10.2 kDa secreted
                                                                                                                                   putative 10.2 kDa secreted
                                                                                                                                   putative 10.2 kDa secreted
                                                                                                                                   putative 10.2 kDa secreted
                                                                                                                                   putative 10.2 kDa secreted
                                                                                               0.053
                                                                                   Opiods_neuropep                                 putative 10.2 kDa secreted
                                                                                                                                   putative 10.2 kDa secreted
                                                                                                                                   putative 10.2 kDa secreted
                                                                                                                                   putative secreted salivary gland pep
                                                                                                           TLDc         0.065      putative secreted salivary gland pep
                                                                                                                                   putative secreted salivary gland pep
                                                                                                                                   putative 10.2 kDa secreted
                                                                                                                                   putative secreted salivary gland pep
                                                                                                                                   putative secreted salivary gland pep
                      GO:0008536
          protein binding               0.075                                                                                      putative secreted salivary gland pep
                                                             0.065 Function unknown
                                                Uncharacterized conserved protein                                                  putative secreted salivary gland pep
                                                             0.098 General       Pox_A30L_A26L 0.040
                                                Arginine N-methyltransferase function prediction only                              putative secreted salivary gland pep
                                                                                                                                   putative secreted salivary gland pep
                                                                                                                                   putative 6.4 kDa secreted p
                                                                                                                                   putative secreted salivary gland pep

                                                                                                                                   putative peptide 14.4 kDa [Ixodes pa
                                                RNA helicase 0.062      RNA processing and modification                            putative peptide 11.9 kDa [Ixodes pa
                                                                                                                                   putative peptide 11.9 kDa [Ixodes pa
                                                                                                                                   putative peptide 14.4 kDa [Ixodes pa
                       GO:0003743        0.001
          translation factor activity\, nucleic acid binding                       eIF-4B      0.047                               putative peptide 14.4 kDa [Ixodes pa
                                                                                   KorB_C      0.050                               putative secreted salivary gland pep
                     GO:0005086
          GTPase regulator activity     0.005                                                  0.052
                                                                                   Mannosyl_trans                                  salivary gland 16 kD protei
                     GO:0004930
          receptor activity             0.095                                                                                      putative peptide 14.4 kDa [Ixodes pa
                                                                                                                                   putative secreted salivary gland pep
                                                                                                                                   salivary gland 16 kD protei
                      GO:0005554
molecular_function unknown              0.015                                                                                      salivary gland 16 kD protei



                    GO:0004867
          enzyme inhibitor activity    1E-21 Serpin            6E-030   Defense mechanisms
                                                                                 Serpin         7E-032     SERPIN      1E-031      putative serpin [Ixodes sca
                    GO:0004867
          enzyme inhibitor activity    8E-55 Serpin            7E-081   Defense mechanisms
                                                                                 Serpin         8E-088     SERPIN      1E-088      putative secreted salivary gland pep

                    GO:0004869
          enzyme inhibitor activity     0.072                                      Cystatin     8E-007     CY          2E-009      putative secreted cystatin
                     GO:0004869
           enzyme inhibitor activity   0.072                                    Cystatin     9E-008     CY         6E-009     putative secreted cystatin

                      GO:0004872
           receptor activity           0.003                                                                                  von Willebrand factor [Ixodes ricinus
                      GO:0005554
molecular_function unknown                                  0.018
                                       0.005 Neurexin III-alpha       Signal transduction mechanisms                          BTSP-11 [Ixodes pacificus]

                       GO:0003700                           9E-004 IntracellularTT_ORF1 secretion, and vesicular transport
                                                                                   trafficking, 0.005
           transcription factor activity 5E-09 Vesicle coat complex AP-3, beta subunit                                        calreticulin [Ixodes ovatus]
                                                             0.003 Cytoskeleton   Sprouty
                                               Actin filament-binding protein Afadin            0.013                         extracellularmatrix-like protein [Hae
                       GO:0005554 0.0007
molecular_function unknown                                                                                                    cell surface glycoprotein BM86 precu
                       GO:0005201        0.014
           extracellular matrix structural constituent                            Podocalyxin 0.076                           98kDa HDM allergen [Dermatop
                       GO:0042973
           hydrolase activity            0.096                                                                                Is3 [Ixodes scapularis]               6
                       GO:0004295
           hydrolase activity            0.027                                    CBM_14        0.005 ChtBD2        2E-004    mucin/peritrophin-like protein precur
                       GO:0004295
           hydrolase activity            0.027                                    CBM_14        0.005 ChtBD2        2E-004    mucin/peritrophin-like protein precur

                        GO:0004872
            receptor activity                           0.055 Function unknown
                                     0.02 Uncharacterized conserved protein                                                   putative secreted salivary gland pep
                        GO:0005540
            pattern binding         0.011                                                                                     putative secreted salivary gland pep
                        GO:0004871 0.0001 Transcriptional repressor EZH1 Prokineticin
signal transducer activity                              0.010 Transcription                   0.100     COLIPASE   9E-004     putative secreted salivary gland pep



                                                                                                        HOLI       0.058      putative secreted salivary gland pep
                                                                                                                              putative secreted salivary gland pep
                                                                                                                              putative secreted salivary gland pep

                                                                                                                              26 kDa salivary gland prote
                                                                                                                              putative secreted salivary gland pep

                                                                                                                              putative salivary secreted peptide [I
                                                                                                                              putative salivary secreted peptide [I

                                                                                                                              putative salivary secreted peptide [I
                                                                                                                              putative salivary secreted peptide [I

                                                                                                                              cytochrome oxidase subunit I [Petro
                                                                                           0.012
                                                                                E1_DerP2_DerF2                                allergen like protein [Ixodes ricinus]

                       GO:0004187 1E-21 Serine carboxypeptidases (lysosomal cathepsin3E-043
           hydrolase activity                                            transport and A)
                                                     5E-041 Amino acid Peptidase_S10                                        putative secreted carboxype
                                                                                       metabolism, Posttranslational modification, protein turnover, chaperones
                       GO:0004295 4E-65 Trypsin
           hydrolase activity                                            transport    3E-046 Tryp_SPc
                                                     1E-057 Amino acid Trypsin and metabolism                  2E-066       fed tick salivary protein 10 [Ixodes
                       GO:0004252 9E-33 Trypsin
           hydrolase activity                                            transport    2E-034 Tryp_SPc
                                                     1E-043 Amino acid Trypsin and metabolism                  5E-051       fed tick salivary protein 10 [Ixodes
                                                     9E-011              transport and metabolism
           ion binding GO:0008270 0.0002 M13 family peptidase Amino acid Peptidase_M136E-006                                neutral endopeptidase-like
                       GO:0004246 1E-10 Angiotensin I-converting enzymes Peptidase_M2metabolism
           hydrolase activity                                            transport and E-009
                                                                                      3
                                                     6E-011 Amino acid - M2 family peptidases                               angiotensin-converting enzyme-like
                                                                         GCN5L1        0.010                                NADH dehydrogenase subunit 4 [Ixo
                       GO:0004623 3E-13
           hydrolase activity                                            PLA2G12      1E-012                                putative salivary secreted peptide [I

                                                                                                                              KUN-1 [Ixodes pacificus]
                                                                                                                              NADH dehydrogenase 4 [Ornithodor

                                                                                                                              acetylcholinesterase [Boophilus mic
                                                                                                                              putative secreted peptide of 6.3 kDa

                                                                                                                              acetylcholinesterase [Rhipicephalus
                                                                                                                              thrombin inhibitor [Ornithodoros mou
                                                                                                                              group 3 allergen SMIPP-S Yv6017G
                                                                                                                              putative salivary secreted peptide [I
                                                                                                                              putative secreted protein [
                                                                                                                              putative 4.3 kDa secreted p
                                                              0.063
                                               Sialyltransferase      Carbohydrate transport and metabolism                   putative salivary secreted peptide [I
                                                                                                                              cell surface glycoprotein BM86 precu
                                                            0.056     proteins
                                               FYVE finger-containingGeneral function prediction only                         putative secreted peptide of 4.99 kD

                                                                                                                              BM86-like protein [Hyalomma
                                                                                                                              putative secreted peptide of 6.3 kDa
                                                                                                                              hypothetical protein [Ixodes pacificus
                                                                                                                                  trypsin [Blomia tropicalis]
                                                                                                                                  putative secreted salivary gland pep
                                                                                                                                  putative secreted protein [
                                                                                                                                  putative peptide 11.9 kDa [Ixodes pa
                                                                                                                                  RNA polymerase II largest subunit [C
                      GO:0005070        0.02
          receptor signaling protein activity                                                                                     secreted protein PK-4 precursor [Orn
                                                                                                                                  putative secreted salivary gland pep
                                                                                                                                  putative salivary secreted peptide [I
                                                                                                                                  putative secreted salivary gland pep

                                                                                                                                  cell surface glycoprotein BM86 precu
                                                                                                                                  thrombin inhibitor [Ornithodoros mou
                      activity
          transferase GO:0004653       0.015                                                                                      putative secreted salivary gland pep
                       binding
          nucleic acidGO:0003723       0.015                                                                                      putative cement protein RIM36 [Rhip
                                                                                                                                  putative secreted salivary gland pep

                                                       0.065     ABC50 (ABC superfamily)
                                                                             ribosomal structure and biogenesis
          ion binding GO:0008270 0.0008 eIF2-interacting proteinTranslation,KorB_C        0.016                                  heat shock protein 82 [Tectocepheu
                                                                                                                                 NADH dehydrogenase 4 [Ixodes hex
                      GO:0005554
molecular_function unknown            3E-26     Defense-related protein containingSCP domain4E-017 SCP
                                                              9E-022 Function unknown SCP                               1E-025   Is4 [Ixodes scapularis]             2
                                                                                                                                 secreted protein [Ixodes ricinus]
                                                                                                           HTH_ARAC      0.042   unknown secreted protein PK-26 pre
                                                                                                                                 RNA polymerase II largest subunit [Z
                     GO:0003823
          antigen binding             2E-27                   3E-037 General proteinsFibrinogen_C3E-029
                                                Ficolin and related extracellular function prediction only FBG          2E-038   Ixoderin B [Ixodes ricinus]
                                                              1E-011 Function unknown
                                                Uncharacterized conserved protein                                                putative secreted salivary gland pep
                      GO:0003714
          transcription cofactor activity 0                                          Calreticulin 1E-111
                                                Calreticulin 1E-141 Posttranslational modification, protein turnover, chaperones calreticulin [Ixodes scapularis]
                      GO:0005515 3E-11
          protein binding                                     5E-006 RNA processing and modification,
                                                                                     Daxx                                        heat shock protein
                                                Ribosome biogenesis protein - Nop56p/Sik1p 3E-005 Translation, ribosomal structure and biogenesis 82 [Steganacarus
                                                                                                                                 putative glutathione S-transferase [D
          Clustered             Clustered             Clustered             Clustered
           at 60%-               at 70%-               at 80%-               at 90%-              Clustered           Clustered
           Sim- on               Sim- on               Sim- on               Sim- on              at 90%-Id-          at 95%-Id-
           60% of                60% of                60% of                60% of                 on 90%              on 95%
          length - -            length - -            length - -            length - -            of length -         of length -
E value   Cluster#     # seqs   Cluster#     # seqs   Cluster#     # seqs   Cluster#     # seqs   - Cluster# # seqs   - Cluster#


1E-069        1         306         2          63         1          35         1          23        1         21         2
9E-070        1         306         2          63         1          35         1          23        1         21         2
4E-075        1         306         2          63         1          35         1          23        1         21         2
1E-073        1         306         2          63         1          35         1          23        1         21         2
8E-073        1         306         2          63         1          35         1          23        1         21         2
1E-076        1         306         2          63         1          35         1          23        1         21         5
1E-074        1         306         2          63         1          35         1          23        1         21         5
2E-069        1         306         2          63         1          35         1          23        1         21         5
1E-070        1         306         2          63         1          35         1          23        1         21         6
2E-075        1         306         2          63         1          35         1          23        1         21        34
2E-068        1         306         2          63         1          35         1          23        1         21        34
6E-071        1         306         2          63         1          35         1          23        1         21        289
3E-074        1         306         2          63         1          35         1          23        1         21        419
2E-074        1         306         2          63         1          35         1          23        1         21        270
2E-076        1         306         2          63         1          35         1          23        1         21        581
9E-072        1         306         2          63         1          35         1          23        1         21        585
2E-074        1         306         2          63         1          35         1          23        1         21        422
1E-066        1         306         2          63         1          35         1          23        1         21        583
1E-073        1         306         2          63         1          35         1          23        1         21        584
2E-076        1         306         2          63         1          35         1          23        1         21        428
4E-076        1         306         2          63         1          35         1          23        1         21        421
6E-074        1         306         2          63         4          15         2          15        2         15         1
6E-074        1         306         2          63         4          15         2          15        2         15         1
5E-074        1         306         2          63         4          15         2          15        2         15         1
2E-068        1         306         2          63         4          15         2          15        2         15         1
5E-074        1         306         2          63         4          15         2          15        2         15         1
3E-072        1         306         2          63         4          15         2          15        2         15         1
8E-074        1         306         2          63         4          15         2          15        2         15         1
2E-065        1         306         2          63         4          15         2          15        2         15         1
5E-074        1         306         2          63         4          15         2          15        2         15         1
1E-073        1         306         2          63         4          15         2          15        2         15         6
8E-074        1         306         2          63         4          15         2          15        2         15         6
6E-071        1         306         2          63         4          15         2          15        2         15         9
1E-066        1         306         2          63         4          15         2          15        2         15         9
2E-074        1         306         2          63         4          15         2          15        2         15        456
6E-074        1         306         2          63         4          15         2          15        2         15        146
1E-043        1         306        11           5        135          1        140          1       132         1        441
1E-059        1         306         2          63         1          35         1          23       278         1        474
7E-052        1         306        11           5        301          1        334          1       338         1        131
5E-046        1         306        11           5        302          1        335          1       339         1        358
2E-063        1         306        11           5        365          1        406          1       411         1        359
4E-073        1         306         2          63         1          35        524          1       538         1         9

3E-060        1         306         2          63         1          35         3          11        3         11        586
3E-057        1         306         2          63         1          35         3          11        3         11        587
1E-054   1   306    2    63     1    35    3    11    3    11   536
6E-049   1   306    2    63     1    35    3    11    3    11   295
7E-050   1   306    2    63     1    35    3    11    3    11   298
2E-048   1   306    2    63     1    35    3    11    3    11   299
2E-049   1   306    2    63     1    35    3    11    3    11   271
3E-048   1   306    2    63     1    35    3    11    3    11   274
2E-047   1   306    2    63     1    35    3    11    3    11   21
7E-047   1   306    2    63     1    35    3    11    3    11   21
3E-046   1   306    2    63     1    35    3    11    3    11   273
  2.2    1   306   164    1    210    1   225    1   221    1   225
3E-063   1   306    2    63     1    35    1    23   539    1   582



3E-035   1   306    1    105   165    1   176   1    169   1    172
8E-056   1   306    1    105    3    20   50    2    40    2    31
6E-056   1   306    1    105    3    20   50    2    40    2    31
1E-056   1   306    1    105    3    20   525   1    540   1    588
8E-053   1   306    1    105    3    20    7    5     7    5     7
2E-051   1   306    1    105   30     2   21    2    18    2    15
5E-053   1   306    1    105   30     2   21    2    18    2    15
5E-056   1   306    1    105   416    1   464   1    472   1    508
7E-056   1   306    1    105    3    20   11    3    10    3    30
7E-056   1   306    1    105    3    20   11    3    10    3    30
5E-053   1   306    1    105    3    20    7    5     7    5     7
8E-051   1   306    1    105    3    20   11    3    10    3    81
9E-033   1   306    1    105    3    20   10    3    267   1    278
5E-047   1   306    1    105    3    20   506   1    516   1    555
5E-032   1   306    1    105   359    1   399   1    404   1    432
3E-030   1   306    1    105   133    1   138   1    130   1    128
6E-054   1   306    1    105   465    1   519   1    530   1    572
8E-048   1   306    1    105   58     2   523   1    536   1    579
9E-023   1   306    1    105   29     2   20    2    16    2    88
8E-022   1   306    1    105   29     2   20    2    16    2    343
7E-027   1   306   109    1    137    1   142   1    134   1    133
5E-057   1   306    1    105   466    1   520   1    531   1    573
1E-056   1   306    1    105    5    10   22    2    19    2    16
2E-055   1   306    1    105    5    10   22    2    19    2    16
1E-034   1   306    9     5    101    1   102   1    94    1    90
8E-029   1   306    1    105   118    1   122   1    114   1    111
3E-044   1   306    1    105   15     3   27    2    24    2    163
4E-049   1   306    1    105   15     3   27    2    24    2    574
1E-042   1   306    1    105   15     3   172   1    164   1    167
6E-030   1   306    1    105   121    1   125   1    117   1    114
3E-028   1   306   59     1    61     1   54    1    44    1    36
3E-027   1   306    1    105   104    1   105   1    97    1    93
3E-049   1   306    9     5    11     4   522   1    535   1    578
2E-042   1   306    9     5    11     4   395   1    400   1    426
1E-046   1   306    1    105   28     2   19    2    90    1    85
2E-035   1   306   30     2    100    1   101   1    93    1    89
2E-048   1   306   30     2    467    1   521   1    533   1    576
2E-049   1   306    1    105   28     2   19    2    532   1    575
1E-052   1   306    1    105    3    20    7    5     7    5     7
1E-049   1   306    1    105    3    20    7    5     7    5    352
1E-056   1   306    1    105    3    20    7    5     7    5    544
1E-038   1   306    1    105    3    20   10    3    69    1    62
5E-033   1   306    1    105    3    20   126   1    118   1    115
8E-040   1   306    1    105    3    20   10    3    178   1    181
1E-053   1   306    1    105    5    10   12    3    17    2    14
3E-054   1   306    1    105    5    10   12    3    17    2    14
2E-040   1   306    1    105    5    10   12    3    537   1    580
1E-054   9    4    19     3    16     3   13    3    11    3     8
2E-054   9    4    19     3    16     3   13    3    11    3     8
2E-056   9    4    19     3    16     3   13    3    11    3     8
9E-043    1    306    1    105   44    2    35    2   265   1   275
1E-046    1    306    1    105   44    2    35    2   534   1   577
4E-046    1    306   58     2    59    2    52    2   42    2   33
1E-046    1    306   58     2    59    2    52    2   42    2   33
8E-028    1    306    1    105   63    1    58    1   48    1   40
2E-035    1    306    1    105   260   1    285   1   288   1   303
1E-008    1    306   270    1    345   1    378   1   382   1   402
 0.003    1    306   287    1    373   1    414   1   419   1   450
8E-056   17     2    328    1    420   1    468   1   476   1   512
9E-058    1    306    1    105   464   1    518   1   528   1   567

1E-035   17     2    64    1     69    1    66    1   56    1   48
2E-013   73     1    100   1     123   1    128   1   120   1   117
1E-088    1    306   70    1     78    1    76    1   66    1   59
1E-101   43     2    346   1     442   1    491   1   500   1   537
1E-106   43     2    353   1     454   1    507   1   517   1   556
1E-046    2    12     6    8     280   1    308   1   312   1   328
3E-044    2    12     6    8     291   1    321   1   325   1   342
1E-045    2    12     6    8     374   1    417   1   422   1   453
1E-045    2    12     6    8     42    2    257   1   255   1   261
9E-045    2    12     6    8     237   1    256   1   254   1   260
4E-006   166    1    225   1     295   1    325   1   329   1   347

1E-106    1    306    4    12    293   1    323   1   327   1   345
2E-014   71     1    97     1    119   1    123   1   115   1   112
1E-130    1    306    4    12    270   1    296   1   299   1   315
9E-060   74     1    104    1    127   1    132   1   124   1   121
1E-143   35     2    214    1    277   1    303   1   306   1   322
  0.0    35     2    358    1    461   1    515   1   525   1   564
  0.0     1    306   57     2    463   1    517   1   527   1   566
  0.0     1    306   57     2    462   1    516   1   526   1   565

4E-005   200    1    265    1    340    1   373   1   377   1   397
3E-035    1    306    1    105    2    24    8    4    8    4    3
2E-034    1    306    1    105    2    24    5    5    5    5   24
1E-034    1    306    1    105    2    24    4    7    4    6   13
4E-021    1    306    1    105   64     1   59    1   49    1   41
6E-036    1    306    1    105    5    10    6    5    6    5   12
3E-030    1    306    1    105    2    24   88    1   79    1   72
1E-032    1    306    1    105    2    24   87    1   78    1   71
8E-037    1    306    1    105    2    24    8    4    8    4    3
3E-032    1    306    1    105    2    24    5    5    5    5   11
3E-005    1    306    1    105   37     2   440   1   445   1   479
9E-029    1    306    1    105   10     4   187   1   181   1   184
8E-030    1    306    1    105   10     4   180   1   173   1   176
8E-029    1    306    1    105    2    24   179   1   172   1   175
3E-006    1    306    1    105    3    20   173   1   166   1   169
7E-004    1    306    1    105   36     2   28    2   165   1   168
2E-027    1    306    1    105   10     4   171   1   163   1   166
9E-023    1    306    1    105   162    1   170   1   162   1   165
1E-032    1    306    1    105    2    24    4    7    4    6   145
6E-030    1    306    1    105    2    24   151   1   143   1   143
2E-032    1    306    1    105    2    24    5    5    5    5   142
5E-006    1    306    1    105   139    1   144   1   136   1   135
3E-009    1    306   181    1    228    1   244   1   242   1   246
2E-021    1    306    1    105   202    1   217   1   213   1   216
2E-033    1    306    1    105   200    1   215   1   211   1   214
 0.002    1    306    1    105   36     2   28    2   210   1   213
3E-029    1    306    1    105   197    1   212   1   207   1   210
3E-005    1    306    1    105   177    1   192   1   186   1   189
2E-005    1    306    1    105   37     2   190   1   184   1   187
7E-033    1    306    1    105    2    24    4    7    4    6   27
  3.6    5      6    31     2    31     2   416   1   421   1   452
4E-032   1     306    1    105    2    24    4    7    4    6   27
3E-030   1     306    1    105   10     4   415   1   420   1   451
3E-025   1     306   280    1    357    1   396   1   401   1   427
5E-012   1     306   277    1    354    1   390   1   395   1   416
2E-031   1     306    1    105    2    24    4    7    4    6   410
4E-031   1     306    1    105    2    24    5    5    5    5   11
2E-037   1     306    1    105    2    24    8    4    8    4    3
1E-037   1     306    1    105    2    24    8    4    8    4    3
1E-037   1     306    1    105    5    10    6    5    6    5   568
5E-037   1     306    1    105    2    24    4    7    4    6   13
1E-037   1     306    1    105    5    10    6    5    6    5   569
1E-037   1     306    1    105    5    10    6    5    6    5   12
2E-037   1     306    1    105    5    10    6    5    6    5   570
1E-037   1     306    1    105    2    24   51    2   41    2   32
2E-036   1     306    1    105    2    24    5    5    5    5   24
3E-037   1     306    1    105    2    24   51    2   41    2   32
8E-038   1     306    1    105    2    24   16    2   13    2   10
2E-029   1     306    1    105    2    24    4    7   529   1   571

2E-021   1     306   42     2    364   1    405   1   410   1   440
9E-055   1     306   288    1    375   1    419   1   424   1   457
1E-054   1     306   41     2    41    2    253   1   251   1   255
2E-046   1     306    3    14    182   1    197   1   191   1   194
7E-023   1     306    4    12    194   1    209   1   204   1   207
1E-116   1     306   347    1    444   1    494   1    1

5E-026    1    306    1    105    2    24   16    2   13    2   10
5E-018   160    1    217    1    283    1   311   1   315   1   331
 0.014    5     6    31     2    31     2   112   1   104   1   101
2E-006    5     6    207    1    265    1   290   1   293   1   308
1E-011    1    306    1    105   67     1   63    1   53    1   45
4E-012    1    306   62     1    66     1   61    1   51    1   43
3E-014   120    1    159    1    201    1   216   1   212   1   215
2E-023    1    306    2    63    45     2   36    2   28    2   455
7E-023    1    306    2    63    45     2   36    2   28    2   276
1E-021   118    1    157    1    196    1   211   1   206   1   209
6E-041    1    306    2    63    448    1   499   1   508   1   547
4E-026    1    306    2    63    250    1   270   1   271   1   282
8E-024    1    306    2    63    20     3   436   1   441   1   475
2E-023    1    306    2    63    253    1   276   1   279   1   290
4E-020    5     6    17     3    106    1   107   1   99    1   95
3E-022    5     6    17     3    368    1   409   1   414   1   444
2E-020    5     6    17     3    115    1   118   1   110   1   107

2E-031   1     306    8     5    261   1    286   1   289   1   304
3E-074   1     306   51     2    52    2    42    2   33    2   25
5E-038   1     306    8     5    13    3    305   1   309   1   325
2E-045   4      6    12     4    276   1    302   1   305   1   321
1E-053   4      6    12     4    24    2    62    1   52    1   44
2E-041   1     306    8     5    13    3    18    2   15    2   84
2E-045   4      6    12     4    95    1    96    1   87    1   80
2E-035   1     306    8     5    128   1    133   1   125   1   122
7E-025   1     306    2    63    20    3    43    2   35    2   425
7E-025   1     306    2    63    20    3    43    2   35    2   424
1E-075   1     306   51     2    52    2    42    2   33    2   25
3E-062   4      6    12     4    24    2    497   1   506   1   543
1E-043   1     306    8     5    13    3    18    2   15    2   545

 0.0     7     5     56    2     57    2    48    2   511   1   550
 0.0     7     5     23    3     22    3    49    2   39    2   29
 0.0     7     5     23    3     22    3    49    2   39    2   29
 0.0     7     5     23    3     22    3   502   1   512   1   551

9E-012    1    306    1    105   34    2   394   1   399   1   423
3E-011    1    306    1    105   34    2   149   1   141   1   140
5E-012    1    306   279    1    356   1   393   1   398   1   420
5E-008   36     2    48     2    282   1   310   1   314   1   330


1E-006   36    2     48    2     370   1   411   1   416   1   446



  8.8     1    306    3    14    53    2   380   1   384   1   404
4E-041   149    1    201    1    256   1   280   1   283   1   296
1E-010    1    306   227    1    297   1   328   1   332   1   350
6E-050    1    306   50     2    287   1   315   1   319   1   335
2E-044    1    306   218    1    285   1   313   1   317   1   333
  6.2     1    306    9     5    11    4   33    2   307   1   323
4E-043    1    306   40     2    273   1   299   1   302   1   318
5E-023    1    306   212    1    272   1   298   1   301   1   317
2E-039    1    306    1    105   71    1   68    1   58    1   51
5E-039    1    306    4    12    109   1   110   1   102   1   98
4E-019    1    306    4    12    103   1   104   1   96    1   92
2E-040    1    306   29     2    92    1   93    1   84    1   77
3E-054    1    306    4    12    12    3   92    1   83    1   76
3E-014   78     1    110    1    138   1   143   1   135   1   134
9E-037   23     2    107    1    134   1   139   1   131   1   130
1E-005    1    306   99     1    122   1   127   1   119   1   116
5E-058    1    306    4    12    12    3   438   1   443   1   477
9E-008   39     2    52     2    409   1   457   1   465   1   501
 0.012   215    1    295    1    383   1   427   1   432   1   465
6E-008    1    306   11     5    169   1   182   1   175   1   178
9E-045    1    306   133    1    163   1   174   1   167   1   170
  1.9     1    306    9     5    11    4   33    2   257   1   263
3E-043    1    306   40     2    234   1   251   1   249   1   253
9E-030   30     2    38     2    40    2   31    2   25    2   19
9E-030   30     2    38     2    40    2   31    2   25    2   19
4E-028    1    306   286    1    369   1   410   1   415   1   445
 0.008    1    306    2    63    366   1   407   1   412   1   442
1E-004   23     2    283    1    361   1   402   1   407   1   437
6E-024    1    306    1    105   19    3   14    3   34    2   26
4E-007   39     2    52     2    352   1   388   1   393   1   414
3E-065   42     2    335    1    430   1   479   1   488   1   524
4E-067   248    1    341    1    437   1   486   1   495   1   531
1E-077    1    306   342    1    438   1   487   1   496   1   532
1E-070    1    306   50     2    458   1   511   1   521   1   560
2E-067    1    306    4    12    12    3   512   1   522   1   561
7E-086    1    306   361    1    470   1   529   1   545   1   594
2E-078    1    306   16     3    471   1   530   1   546   1   595
5E-067   259    1    362    1    472   1   532   1   548   1   597

7E-070   11     4    14     4    268   1   294   1   297   1   312
2E-007    1    306   16     3    257   1   282   1   285   1   300
1E-100   10     4    20     3    18    3   281   1   284   1   297
7E-015   148    1    200    1    255   1   279   1   282   1   294
3E-014    3    11     5     9    46    2   278   1   281   1   293
2E-096    1    306    3    14     9    4   24    2   21    2   18
 0.011   32     2    199    1    254   1   277   1   280   1   291
5E-091    1    306    3    14     9    4   37    2   277   1   288
1E-105    1    306   10     5     7    5   275   1   276   1   287
1E-104    1    306   10     5     7    5   274   1   275   1   286
1E-104    1    306   10     5     7    5   272   1   273   1   284
3E-006   145    1    196    1    249   1   269   1   270   1   281
1E-101    6     5    18     3    246   1   266   1   266       1        277
3E-011   16     3    21     3    299   1   332   1   336       1        356
1E-015   16     3    21     3    51    2   331   1   335       1        355
1E-013    3    11     5     9    46    2   330   1   334       1        354
7E-089   11     4    14     4    50    2   326   1   330       1        348
9E-005   165    1    223    1    292   1   322   1   326       1        344
1E-106   10     4    20     3    18    3   320   1   324       1        341
2E-014   16     3    21     3    51    2   319   1   323       1        340
4E-064    2    12    49     2    284   1   312   1   316       1        332
2E-020   34     2    47     2    279   1   307   1   311       1        327
5E-087   11     4    14     4    50    2   306   1   310       1        326
1E-079    1    306   215    1    278   1   304   1   308       1        324
3E-019   34     2    47     2    275   1   301   1   304       1        320
9E-085    6     5    25     2    26    2   17    2   14        2        99
5E-081    6     5    25     2    26    2   17    2   14        2        49
1E-132    1    306    3    14     8    4    9    4    9        4         4
1E-023    1    306   16     3    96    1   97    1   88        1        82
1E-110    1    306   10     5     7    5   115   1   107       1        104
4E-039   13     3    102    1    125   1   130   1   122       1        119
8E-044   13     3    101    1    124   1   129   1   121       1        118
2E-093    1    306    3    14     9    4   24    2   21        2        18
1E-106    6     5    18     3    32    2   119   1   111       1        108
3E-007    1    306   299    1    388   1   433   1   438       1        471
4E-076    2    12    49     2    376   1   420   1   425       1        458
6E-015    3    11    187    1    239   1   259   1   258       1        264
6E-010    3    11     5     9    238   1   258   1   256       1        262
 0.013   128    1    172    1    219   1   234   1   232       1        236
4E-011    3    11    161    1    207   1   222   1   218       1        222
6E-061    8     4    36     2    205   1   220   1   216       1        220
1E-139    8     4    334    1    429   1   478   1   487       1        523
1E-134    6     5    18     3    32    2   492   1   501       1        538
1E-127   11     4    14     4    443   1   493   1   502       1        539
1E-133   255    1    355    1    457   1   510   1   520       1        559
1E-135    1    306    3    14     8    4    9    4    9        4         4
  0.0    13     3    356    1    459   1   513   1   523       1        562
  0.0    256    1    357    1    460   1   514   1   524       1        563
1E-135    1    306    3    14     8    4    9    4    9        4         4
1E-132   10     4    20     3    18    3   527   1   542       1        590
1E-135    1    306    3    14     8    4    9    4    9        4         4
6E-089    1    306    3    14     9    4   37    2   544       1        593
1E-134    1    306   10     5     7    5   531   1   547       1        596

8E-046   1     306    1    105   58    2   472   1   481       1        517
1E-095   1     306   32     2    422   1   470   1   479       1        515
3E-017   1     306   44     2    47    2   401   1   406       1        436
1E-038   1     306    1    105   116   1   120   1   112       1        109



1E-041   1     306   55    2     56    2   47    2   478       1        514

6E-013   1     306    2    63    25    2   64    1   54        1        46
4E-012   1     306    2    63    25    2   385   1   389       1        409



2E-066   151   1     203   1     259   1   284   1   137        1 ISNU-L-ISN-78
1E-132   260   1     363   1     473   1   533   1              4
                                                      6 gi|15428288|gb|AAK97814.1|AF209911_1
2E-066   15    3     176   1     223   1   238   1    6         4      IS-6-12-J-cluster-514
2E-064   15    3     43    2     43    2   34    2    6         4      ISNU-L-ISN-123
4E-066   15    3     43    2     43    2   34    2    6         4 IS-6-12-J-IS612-476

 3.7     70    1     95    1     114   1   117   1   109       1        106
 1.7     45    1     63    1     68    1   65    1   55        1        47
 3.0     33    2     45    2    48    2   39    2   30    2   22

3E-097    3    11     5    9     6    6   40    2   31    2   313
1E-084    3    11     5    9     6    6   38    2   29    2   292
4E-084    3    11     5    9     6    6   38    2   29    2   351
2E-095    3    11     5    9     6    6   44    2   36    2   449
1E-108    3    11     5    9     6    6   44    2   36    2   600
3E-045   257    1    359   1    468   1   526   1   541   1   589
1E-106    3    11     5    9     6    6   40    2   31    2   592

 0.001    1    306    7     7   17    3   248   1   246   1   250
 0.30     1    306    7     7   17    3   32    2   26    2   258
 0.38     1    306    7     7   17    3   32    2   26    2   259
2E-020    1    306   22     3   21    3   15    3   12    3   434
5E-034    1    306   13     4   14    3   25    2   22    2   125
3E-036    1    306   13     4   14    3   25    2   22    2   339
2E-021    1    306   22     3   21    3   15    3   12    3   433
4E-027    1    306    4    12   363   1   404   1   409   1   439
4E-030   210    1    282    1   360   1   400   1   405   1   435
1E-027   207    1    276    1   353   1   389   1   394   1   415
2E-048    1    306   15     3   193   1   208   1   202   1   205
4E-024    1    306   22     3   21    3   15    3   12    3   429
1E-032   12     3    26     2   27    2   397   1   402   1   430
3E-050    1    306    3    14   372   1   413   1   418   1   448
2E-035   167    1    226    1   296   1   327   1   331   1   349
2E-025    1    306    4    12   164   1   175   1   168   1   171
5E-032    1    306   13     4   14    3   383   1   387   1   407
2E-030    1    306   13     4   132   1   137   1   129   1   127
2E-051    1    306    3    14   371   1   412   1   417   1   447
4E-029   12     3    90     1   107   1   108   1   100   1   96
1E-032   12     3    26     2   27    2   70    1   60    1   53
2E-067    1    306    3    14   445   1   495   1   504   1   541
2E-068   25     2    336    1   431   1   480   1   489   1   525
9E-073    1    306   15     3   426   1   475   1   484   1   520
5E-016   20     2    89     1   105   1   106   1   98    1   94
7E-010   72     1    98     1   120   1   124   1   116   1   113
6E-024   20     2    151    1   188   1   203   1   197   1   200
 0.002    1    306    7     7   198   1   213   1   208   1   211
4E-011   77     1    108    1   136   1   141   1   133   1   132
1E-033   29     2    175    1   222   1   237   1   235   1   239
3E-026   85     1    117    1   146   1   153   1   145   1   147
2E-028   209    1    281    1   358   1   398   1   403   1   431
3E-040    1    306    4    12   447   1   498   1   507   1   546
1E-058   29     2    343    1   439   1   488   1   497   1   533

2E-025    1    306    7    7    171   1   184   1   177   1   180
1E-031    1    306   39    2    229   1   245   1   243   1   247
4E-042    1    306   284   1    362   1   403   1   408   1   438
3E-031    1    306   41    2    41    2   255   1   253   1   257
2E-031    1    306   42    2    236   1   254   1   252   1   256
1E-102    1    306   337   1    432   1   481   1   490   1   526
2E-033   162    1    220   1    288   1   316   1   320   1   336
2E-039   53     1    75    1    83    1   81    1   72    1   65
6E-080    1    306   340   1    436   1   485   1   494   1   530
2E-088    2    12    364   1    474   1   534   1   550   1   599
2E-037   150    1    202   1    258   1   283   1   286   1   301



1E-121   28    2     37    2    453   1   505   1   515   1   554
  0.0    245   1     331   1    424   1   473   1   482   1   518

6E-055   18    2     27    2    74    1   72    1   62    1   55
3E-075   18    2     27    2     455   1    508   1   518   1   557

8E-004   1     306   24    2     23    2    56    1   46    1   38
 0.50    1     306   24    2     23    2    57    1   47    1   39

6E-005   76     1    106    1    131    1   136   1   128   1   126
 0.050   116    1    154    1    191    1   206   1   200   1   203
 0.37    122    1    162    1    208    1   223   1   219   1   223
 0.31     1    306   188    1    240    1   260   1   259   1   265
4E-012    1    306   273    1    349    1   384   1   388   1   408
6E-013    1    306    1    105    3    20   23    2   20    2   17
2E-013    1    306    1    105    3    20   23    2   20    2   17

5E-067   1     306   330    1    423   1    471   1   480   1   516
2E-023   1     306    3    14    53    2    391   1   396   1   417
3E-006   1     306   29     2    393   1    441   1   446   1   480



2E-041   2     12     6    8     42    2    418   1   423   1   454
4E-043   2     12     6    8     130   1    135   1   127   1   124
9E-077   2     12     6    8     433   1    482   1   491   1   527

1E-137   258   1     360   1     469   1    528   1   543   1   591
1E-111   247   1     339   1     435   1    484   1   493   1   529

1E-112   22    2     33    2     33    2    26    2   23    2   129
1E-110   22    2     33    2     33    2    26    2   23    2   218

 0.018   1     306    7    7     39    2    30    2   224   1   228
2E-035   1     306    7    7     39    2    30    2   225   1   229

 1.4     27    2     165   1     211   1    226   1   222   1   226
0.001    27    2     224   1     294   1    324   1   328   1   346

  0.0    253   1     352   1     452   1    504   1   514   1   553
  0.0    236   1     319   1     410   1    458   1   14    3
8E-033   158   1     213   1     274   1    300   1   303   1   319
1E-007   164   1     222   1     290   1    318   1   149   1
2E-031   157   1     211   1     271   1    297   1   145   1
 0.36     8    4     65    1     70    1    67    1   35    1
6E-016   21    2     96    1     117   1    121   1   113   1   110

  1.1    138    1    189    1    241   1    261   1   260   1   266
 0.63    126    1    170    1    216   1    231   1   229   1   233
         111    1    147    1    184   1    199   1   193   1   196
 7.4     117    1    156    1    195   1    210   1   205   1   208
 1.1     159    1    216    1    281   1    309   1   313   1   329
         123    1    163    1    209   1    224   1   220   1   224
  4.8    119    1    158    1    199   1    214   1   209   1   212
  2.2    96     1    129    1    158   1    166   1   158   1   160
  9.1    161    1    219    1    286   1    314   1   318   1   334
  1.9    106    1    141    1    176   1    191   1   185   1   188
  1.8    108    1    143    1    179   1    194   1   188   1   191
8E-032   250    1    349    1    449   1    500   1   509   1   548
7E-029   115    1    153    1    190   1    205   1   199   1   202
  2.2     1    306    1    105   203   1    218   1   214   1   217
7E-012   141    1    192    1    244   1    264   1   263   1   269
         168    1    228    1    298   1    329   1   333   1   353
 1.2      1    306   167    1    213   1    228   1   226   1   230
 9.7      1    306   266    1    341   1    374   1   378   1   398
 2.1     75     1    105    1    129   1    134   1   126   1   123
  1.3     1    306    1    105    3    20   240   1   238    1    242
 0.13     1    306   55     2    56     2   47    2   459    1    494
  3.7    136    1    183    1    231    1   247   1   245    1    249
 0.003    1    306   103    1    126    1   131   1   123    1    120
  4.2    110    1    145    1    181    1   196   1   190    1    193
3E-030   171    1    231    1    305    1   338   1   342    1    362
2E-058   244    1    329    1    421    1   469   1   477    1    513
 0.002    8     4    36     2    348    1   382   1   386    1    406
2E-079   42     2    333    1    428    1   477   1   486    1    522
         208    1    278    1    355    1   392   1   397    1    418
 0.18    41     2    54     2    55     2   46    2   38     2    497
  1.7    19     2    28     2    206    1   221   1   217    1    221
 0.002    1    306   60     1    62     1   55    1   45     1    37
 0.008   114    1    152    1    189    1   204   1   198    1    201
3E-099   246    1    332    1    425    1   474   1   483    1    519
         31     2    272    1    347    1   381   1   385    1    405
6E-004   26     2    155    1    192    1   207   1   201    1    204
  2.5    202    1    268    1    343    1   376   1   380    1    400
  2.8     1    306   185    1    233    1   250   1   248    1    252
 0.33    139    1    190    1    242    1   262   1   261    1    267
 0.067   131    1    177    1    224    1   239   1   237    1    241
  3.1    156    1    210    1    269    1   295   1   298    1    314
3E-069   135    1    182    1    230    1   246   1   244    1    248
5E-072    1    306   338    1    434    1   483   1   492    1    528
  0.0    38     2    344    1    440    1   489   1   498    1    534
5E-010   107    1    142    1    178    1   193   1    1    187
 10.0    56     1    78     1    86     1   84    1   47     1
                                         Number
                                             of
                                         matches
         Clustered                         to is-
           by PSI-                      all_blastx
          blast - 4                       _is-all-
         iteraction            View Psi- match-
# seqs        s       # seqs     Blast    maker      E value


  5          1         187                    13
                               IS-18-24-clu17putative 7E-75
  5          1         187     ISNU-L-ISN-1 31        1E-74
  5          1         187                    18      6E-74
                               gi|22164190|gb|AAM93600.1|AF483678_1
  5          1         187     ISNU-L-ISN-4 15        2E-77
  5          1         187                    84      2E-56
                               gi|22164188|gb|AAM93599.1|AF483677_1
  3          1         187                     7      3E-63
                               gi|22164174|gb|AAM93592.1|AF483670_1
  3          1         187     ISN-L-15       10      1E-76
  3          1         187     IS-18-24-clu18b37      1E-74
  3          1         187     ISN-L-16        4      8E-61
  2          1         187                    12      1E-75
                               gi|22164190|gb|AAM93600.1|AF483678_1
  2          1         187     IS-18-24-clu18a13      4E-74
  1          1         187     IS-18-24-Clu16 55      1E-74
  1          1         187                    43      2E-73
                               gi|22164190|gb|AAM93600.1|AF483678_1
  1          1         187                    47      6E-69
                               gi|22164176|gb|AAM93593.1|AF483671_1
  1          1         187                     2      3E-42
                               gi|55736023|gb|AAV63538.1|
  1          1         187     IS-18-24-Clu16 2       5E-58
  1          1         187                     6      6E-75
                               gi|22164186|gb|AAM93598.1|AF483676_1
  1          1         187                    23
                               IS-18-24-clu21putative 2E-72
  1          1         187                    52      7E-72
                               gi|22164164|gb|AAM93587.1|AF483665_1
  1          1         187                     7      1E-72
                               gi|15428308|gb|AAK97824.1|AF209921_1
  1          1         187                     9      2E-72
                               gi|22164192|gb|AAM93601.1|AF483679_1
  9          1         187                    20      3E-74
                               gi|22164154|gb|AAM93582.1|AF483660_1
  9          1         187                     1      1E-58
                               gi|22164180|gb|AAM93595.1|AF483673_1
  9          1         187                     5      3E-74
                               gi|22164166|gb|AAM93588.1|AF483666_1
  9          1         187     is-all-15      12      2E-72
  9          1         187                     3      7E-70
                               gi|22164160|gb|AAM93585.1|AF483663_1
  9          1         187                     2      1E-65
                               gi|22164154|gb|AAM93582.1|AF483660_1
  9          1         187                    13      3E-74
                               gi|22164162|gb|AAM93586.1|AF483664_1
  9          1         187     is-all-10       8      9E-74
  9          1         187                     2      4E-69
                               gi|22164172|gb|AAM93591.1|AF483669_1
  3          1         187                     1      7E-45
                               gi|22164168|gb|AAM93589.1|AF483667_1
  3          1         187                     3      3E-74
                               gi|22164170|gb|AAM93590.1|AF483668_1
  3          1         187     ISN-L-11        4      5E-73
  3          1         187     IS-6-12L-18     7      3E-74
  1          1         187                     5      7E-75
                               gi|22164172|gb|AAM93591.1|AF483669_1
  1          1         187                     1      3E-66
                               gi|22164178|gb|AAM93594.1|AF483672_1
  1          1         187     ISJ-ISPL_P9_D8  7      2E-72
  1          1         187     ISNU-L-ISN-3 1         8E-98
  1          1         187     ISNU-cluster-892       3E-66
  1          1         187     ISNU-cluster-89a1      2E-74
  1          1         187     IS-18-24-clu3845       7E-70
  3          1         187                     3      1E-66
                               gi|22164194|gb|AAM93602.1|AF483680_1

  1          1         187                   153     2E-59
                               gi|22164158|gb|AAM93584.1|AF483662_1
  1          1         187                   20      1E-56
                               gi|22652868|gb|AAN03859.1|AF515779_1
1    1    187                   12    7E-55
                gi|22652868|gb|AAN03859.1|AF515779_1
1    1    187   ISNU-L-ISN-6 11       1E-54
1    1    187   ISNU-L-ISN-6a
1    1    187   ISNU-L-ISN-7 10       5E-54
1    1    187   ISNU-L-ISN-10 2       1E-53
1    1    187   ISNU-L-ISN-12 6       9E-55
2    1    187   ISNU-L-ISN-9 6        1E-55
2    1    187   is-all-17       15    1E-54
1    1    187   ISNU-L-ISN-11 4       6E-55
1   111    1                     1
                IS-6-12-J-cluster-394 3E-37
1    1    187                    2    6E-24
                gi|22164190|gb|AAM93600.1|AF483678_1



1   2     121   IS-6-12L-5-58 3       2E-57
2   2     121                  16     2E-44
                gi|22164254|gb|AAM93632.1|AF483710_1
2   2     121                   3     1E-40
                gi|22164252|gb|AAM93631.1|AF483709_1
1   2     121   gi|15428348|gb|AAK97828.1|AF278575_1
3   2     121                   1     4E-53
                gi|22164248|gb|AAM93629.1|AF483707_1
2   2     121   ISN-L-87        2     7E-43
2   2     121                   1     2E-53
                gi|22164250|gb|AAM93630.1|AF483708_1
1   2     121   gi|55736019|gb|AAV63536.1|
2   2     121                   9     6E-56
                gi|22164258|gb|AAM93634.1|AF483712_1
2   2     121                   4     5E-56
                gi|22164260|gb|AAM93635.1|AF483713_1
3   2     121                   1     2E-53
                gi|22164246|gb|AAM93628.1|AF483706_1
1   2     121   ISN-L-29        9     5E-57
1   2     121   ISNU-L-ISN-1433       2E-44
1   2     121                   5     2E-47
                gi|22164286|gb|AAM93648.1|AF483726_1
1   2     121   IS-18-24-clu2652      4E-54
1   2     121   ISJ-ISPL_P8_C1  1     1E-50
1   2     121                   4     2E-48
                gi|22164218|gb|AAM93614.1|AF483692_1
1   2     121                   5     4E-48
                gi|22164198|gb|AAM93604.1|AF483682_1
1   2     121   ISN-L-53A       2     1E-43
1   2     121   ISNU-cluster-4142     2E-45
1   2     121   ISJ-ISPM_P1_A11 4     4E-55
1   2     121                  12     5E-57
                gi|22164214|gb|AAM93612.1|AF483690_1
2   2     121                   3     4E-55
                gi|22164216|gb|AAM93613.1|AF483691_1
2   2     121   ISN-L-91        2     2E-50
1   2     121   ISN-L-59        6     1E-48
1   2     121   ISJ-ISPL_P5_A8  1     7E-48
1   2     121   IS-6-12L-4    129     5E-49
1   2     121                   2     8E-40
                gi|22164212|gb|AAM93611.1|AF483689_1
1   2     121   IS-6-12L-4B 159       5E-50
1   2     121   ISJ-ISPL_P5_H8  2     9E-46
1   2     121   ISN-L149        1     5E-50
1   2     121   ISN-L-67        4     2E-48
1   2     121                   2     5E-49
                gi|22164204|gb|AAM93607.1|AF483685_1
1   2     121   IS-18-24-clu2 8       2E-49
1   2     121   ISN-L-46       28     2E-61
1   2     121   ISN-L-53        4     4E-34
1   2     121                   1     2E-48
                gi|22164208|gb|AAM93609.1|AF483687_1
1   2     121   gi|22164210|gb|AAM93610.1|AF483688_1
3   1     187   ISN-L-62        4     4E-53
1   1     187   ISNU-cluster-5221     7E-57
1   1     187                   2     2E-36
                gi|22164308|gb|AAM93659.1|AF483737_1
1   2     121   ISN-L-154       2     2E-52
1   2     121   ISJ-ISPL_P6_B2  3     8E-59
1   2     121   IS-6-12L-81     2     1E-56
2   2     121   ISN-L-75        1     1E-27
2   2     121                   2     2E-54
                gi|22164220|gb|AAM93615.1|AF483693_1
1   2     121                   2     1E-20
                gi|22164196|gb|AAM93603.1|AF483681_1
3   2     121   IS-6-12L-86
3   2     121   IS-18-24-clu42 20     1E-56
3   2     121                  17     2E-56
                gi|56159935|gb|AAV80779.1|
1   2     121   ISNU-L-ISN-1252       3E-53
1   2     121                   4     1E-38
                gi|22164206|gb|AAM93608.1|AF483686_1
2   2     121                   4     2E-30
                gi|22164200|gb|AAM93605.1|AF483683_1
2   2     121                  11     2E-42
                gi|22164202|gb|AAM93606.1|AF483684_1
1   2     121   ISN-L341        1     2E-56
1   2     121   ISNU-L-ISN-79 3       1E-54
1   2     121                   1
                ISUFJ-cluster-367     3E-53
1   1     187   IS-18-24-clu5191      3E-42
1   2     121                   2     6E-56
                gi|56159965|gb|AAV80794.1|
1   2     121                   5     4E-58
                gi|22164256|gb|AAM93633.1|AF483711_1

1   2     121   ISN-L709        1      1E-80
1   2     121                   1
                ISJ-ISPL_P6_C11putative9E-92
1   2     121   ISN-L-131       4      1E-102
1   2     121                   2      7E-83
                gi|15077002|gb|AAK83022.1|AF286029_1
1   2     121                   2      3E-75
                gi|22164284|gb|AAM93647.1|AF483725_1
1   2     121   ISNU-cluster-2573      2E-33
1   2     121   ISNU-cluster-4022      1E-100
1   2     121   IS-18-24-clu90 5       1E-109
1   2     121                  10
                IS-6-12-J-IS612-186    1E-106
1   2     121                   4      1E-104
                IS-6-12-J-IS612-151secreted
1   2     121   ISNU-cluster-4842      1E-116

1   2     121                  2
                ISNU-cluster-435     1E-156
1   2     121   ISJ-ISPL_P5_F106     1E-164
1   2     121                  2
                ISNU-cluster-105     1E-147
1   2     121   ISJ-ISPL_P6_F122     1E-121
1   2     121                  3
                ISNU-cluster-203     1E-151
1   2     121                  6     1E-155
                gi|22164266|gb|AAM93638.1|AF483716_1
1   2     121                  1      3E-92
                gi|22164262|gb|AAM93636.1|AF483714_1
1   2     121                  2     1E-129
                gi|22164264|gb|AAM93637.1|AF483715_1

1   187    1    ISUFJ-cluster-2871     5E-49
4    2    121   ISNU-cluster-376 2     5E-23
2    2    121   ISNU-cluster-253 6     1E-33
2    2    121   ISN-L-5         10     9E-36
1    2    121   ISN-L346         3     5E-22
2    2    121   ISN-L-3          8     4E-37
1    2    121   ISN-L-1D         8     2E-37
1    2    121   ISN-L-1C         8     2E-36
4    2    121   ISN-L-1B        13     3E-38
2    2    121   ISN-L-1         29     2E-36
1    2    121   is-all-636       2     1E-40
1    2    121   IS-6-12L-93     46     2E-37
1    2    121   IS-6-12L-54      7     2E-36
1    2    121   IS-6-12L-53      4     3E-36
1    2    121                   22
                IS-6-12L-5-100-92-2-CLU3E-40
1    2    121                   18
                IS-6-12L-5-100-92-1-CLU7E-40
1    2    121   IS-6-12L-49     30     2E-35
1    2    121   IS-6-12L-48      8     3E-54
1    2    121   IS-6-12L-15     39     2E-36
1    2    121   IS-6-12L-12A 7         4E-37
1    2    121   IS-6-12L-12     13     3E-34
1    2    121   IS-6-12L-10     12     4E-48
1    2    121                    3
                IS-6-12-J-cluster-584  2E-62
1    2    121                    8
                IS-6-12-J-cluster-317  6E-36
1    2    121                    5
                IS-6-12-J-cluster-307  5E-57
1    2    121                    2
                IS-6-12-J-cluster-3    6E-32
1    2    121                    1
                IS-6-12-J-cluster-289  1E-36
1    2    121                    2
                IS-6-12-J-cluster-108  3E-36
1    2    121                    1
                IS-6-12-J-cluster-101  2E-37
2    2    121   IS-18-24-clu8a 21      7E-37
1   198    1    IS-18-24-clu86 6      5E-46
2    2    121   IS-18-24-clu8 1       1E-36
1    2    121   IS-18-24-clu7a 25     2E-36
1   64     1    IS-18-24-clu2176      6E-53
1    2    121   IS-18-24-clu14 1      1E-22
1    2    121   IS-18-24-clu11 16     7E-37
2    2    121   IS-18-24-clu10 41     1E-35
4    2    121                   1     2E-31
                gi|22164244|gb|AAM93627.1|AF483705_1
4    2    121                  11     5E-38
                gi|22164242|gb|AAM93626.1|AF483704_1
1    2    121                   4     6E-35
                gi|22164240|gb|AAM93625.1|AF483703_1
2    2    121                   4     5E-35
                gi|22164238|gb|AAM93624.1|AF483702_1
1    2    121                   5     6E-38
                gi|22164236|gb|AAM93623.1|AF483701_1
2    2    121                   2     1E-30
                gi|22164234|gb|AAM93622.1|AF483700_1
1    2    121                   4     2E-34
                gi|22164232|gb|AAM93621.1|AF483699_1
2    2    121                  12     5E-38
                gi|22164226|gb|AAM93618.1|AF483696_1
2    2    121                  13     7E-37
                gi|22164228|gb|AAM93619.1|AF483697_1
2    2    121                  11     4E-36
                gi|22164226|gb|AAM93618.1|AF483696_1
2    2    121                  10     3E-38
                gi|22164224|gb|AAM93617.1|AF483695_1
1    2    121                   1     4E-10
                gi|22164222|gb|AAM93616.1|AF483694_1

1   1     187                   45
                IS-18-24-clu37putative 1E-113
1   1     187   is-all-328      12     8E-74
1   1     187                    2
                IS-6-12-J-cluster-88   1E-109
1   1     187                   16
                IS-6-12-J-cluster-14   1E-109
1   1     187                    5
                IS-6-12-J-cluster-26   1E-113
          187                    3     6E-79
                gi|22164316|gb|AAM93663.1|AF483741_1

2   1     187   ISN-L175         2    2E-17
1   1     187   ISNU-cluster-297 2    9E-39
1   1     187   ISN-L-92         3    9E-39
1   1     187   ISNU-L-ISNU-171  5    3E-42
1   1     187   ISN-L520         2    9E-39
1   1     187   ISN-L409         2    1E-38
1   1     187                    1
                IS-6-12-J-cluster-308 6E-40
1   1     187   is-all-122      15    2E-37
1   1     187   ISNU-L-ISN-1263       3E-37
1   1     187                    2
                IS-6-12-J-cluster-281 7E-12
1   1     187                    1    2E-41
                gi|22164302|gb|AAM93656.1|AF483734_1
1   1     187   ISNU-L-ISN-152  44    4E-40
1   1     187   is-all-332      14    3E-39
1   1     187   ISNU-L-ISN-3A 2       2E-40
1   1     187   ISN-L-76         6    2E-38
1   1     187   IS-18-24-clu4132      1E-35
1   1     187   ISJ-ISPL_P10_A2  2    3E-22

1   4     14    ISNU-L-ISN-82 3       2E-35
2   4     14    ISNU-cluster-4491     1E-76
1   4     14    ISN-L-42        3     5E-43
1   4     14    ISNU-cluster-1891     6E-63
1   4     14                   12
                ISN-L5-100-92-24-CLU 1E-62
1   4     14    ISN-L-42       11     6E-42
1   4     14    ISN-L-25       18     6E-62
1   4     14    ISJ-ISPL_P6_G2  1     4E-43
1   4     14    IS-18-24-clu196b3     3E-64
1   4     14    IS-18-24-clu196b
2   4     14                    3     4E-76
                gi|56159941|gb|AAV80782.1|
1   4     14                   15     4E-62
                gi|22164310|gb|AAM93660.1|AF483738_1
1   4     14                    3     6E-43
                gi|22164306|gb|AAM93658.1|AF483736_1

1   1     187                  8     1E-129
                gi|22164296|gb|AAM93653.1|AF483731_1
2   1     187   gi|31322780|gb|AAP22067.1|
2   1     187                 31     1E-163
                gi|31322780|gb|AAP22067.1|
1   1     187                  7     1E-112
                gi|22164294|gb|AAM93652.1|AF483730_1

1   9      3    IS-18-24-clu1902     4E-34
1   9      3    IS-6-12L-11    12    6E-34
1   9      3    IS-18-24-clu1893     4E-35
1   1     187   ISNU-cluster-2886    5E-62


1   1     187   IS-18-24-clu45 36    7E-65



1   191    1    ISUFJ-cluster-6441    6E-58
1    1    187   ISNU-L-ISN-67 5       3E-82
1    1    187   ISNU-cluster-518 1    4E-70
1    1    187   ISNU-cluster-340 1    4E-71
1    1    187   ISNU-cluster-310 1    1E-83
1   23     2    ISNU-cluster-218 1    2E-55
1    1    187   ISNU-cluster-155 2    2E-83
1    1    187   ISNU-cluster-154
1    1    187   ISN-L-ISL1179 1       7E-74
1    1    187   ISN-L-872        2    2E-66
1    1    187   ISN-L-650        3    2E-68
1    1    187   ISN-L-218-B      1    3E-68
1    1    187   ISN-L-217A       2    1E-65
1    1    187   ISJ-ISPM_P1_D7   1    6E-45
1    1    187   ISJ-ISPL_P8_D5   1    3E-68
1    1    187   ISJ-ISPL_P6_B5   1    2E-63
1    1    187   is-all-585       2    2E-46
1    1    187   is-all-523       5    5E-70
1    1    187   is-all-407       7    1E-60
1    1    187   IS-6-12L-6      18    8E-82
1    1    187                    8
                IS-6-12L-5-100-92-7   5E-81
1   23     2                     2
                IS-6-12-J-IS612-375   3E-37
1    1    187                    2
                IS-6-12-J-cluster-8   9E-73
2    1    187                    2
                IS-6-12-J-cluster-56  2E-70
2    1    187                    1
                IS-6-12-J-cluster-55  4E-59
1    1    187   IS-18-24-clu4451      6E-70
1    1    187   IS-18-24-clu3964      6E-65
1    1    187   IS-18-24-clu35 46     2E-75
2    1    187   IS-18-24-clu1404      1E-63
1    1    187   IS-18-24-clu1225      1E-70
1    1    187                   11    4E-65
                gi|56159939|gb|AAV80781.1|
1    1    187                    3    2E-66
                gi|56159923|gb|AAV80773.1|
1    1    187                    2    5E-78
                gi|56159921|gb|AAV80772.1|
1    1    187                    4    5E-41
                gi|22164274|gb|AAM93642.1|AF483720_1
1    1    187                    2    6E-62
                gi|22164272|gb|AAM93641.1|AF483719_1
1    1    187                    2    3E-82
                gi|15428296|gb|AAK97818.1|AF209915_1
1    1    187                    2    1E-31
                gi|15428294|gb|AAK97817.1|AF209914_1
1    1    187   gi|15428290|gb|AAK97815.1|AF209912_1

1   3     52    ISNU-L-ISNU-3613    1E-99
1   3     52    ISNU-L-ISN-74 4     1E-109
1   3     52    ISNU-L-ISN-68 3     1E-120
1   3     52    ISNU-L-ISN-58 6     1E-129
1   3     52    ISNU-L-ISN-56 8     1E-133
2   3     52    ISNU-L-ISN-48 16    1E-132
1   3     52    ISNU-L-ISN-47 18    1E-111
1   3     52    ISNU-L-ISN-20 15    1E-132
1   3     52    ISNU-L-ISN-18 4     1E-138
1   3     52    ISNU-L-ISN-17 3     1E-138
1   3     52    ISNU-L-ISN-16 17    1E-134
1   3     52    ISNU-L-ISN-1485     1E-138
1      3      52    ISNU-L-ISN-1303       1E-134
1      3      52    ISNU-cluster-605      1E-148
1      3      52    ISNU-cluster-593      1E-115
1      3      52    ISNU-cluster-571      1E-134
1      3      52    ISNU-cluster-486 1    1E-128
1      3      52    ISNU-cluster-423 1    1E-110
1      3      52    ISNU-cluster-398 2    1E-110
1      3      52    ISNU-cluster-395 1    1E-120
1      3      52    ISNU-cluster-303 1    1E-118
1      3      52    ISNU-cluster-256 1    1E-126
1      3      52    ISNU-cluster-247 2    1E-121
1      1      187   ISNU-cluster-232 1    1E-115
1      3      52    ISNU-cluster-163 2    1E-117
1      3      52    ISN-L-88         3    3E-80
1      3      52    ISN-L88          1    7E-82
4      3      52    ISN-L-44         2    7E-26
1      1      187   ISN-L-33        37    1E-113
1      3      52    ISJ-ISPL-P3-F625 6    1E-140
1      3      52    ISJ-ISPL_P6_D12  1    1E-111
1      3      52    ISJ-ISPL_P6_D10  8    1E-112
2      3      52    ISJ-ISPL_P3_H8
1      3      52                     1
                    ISJ-ISPL_P10_B8_JIN 1E-81
1      3      52    is-all-466       5    1E-111
1      3      52    is-all-330      13    1E-118
1      3      52                     1
                    IS-6-12-J-IS612-39    5E-65
1      3      52                     4
                    IS-6-12-J-IS612-27    1E-117
1      3      52                     1
                    IS-6-12-J-cluster-453 7E-34
1      3      52                     2
                    IS-6-12-J-cluster-38  1E-106
1      3      52                     1
                    IS-6-12-J-cluster-365 3E-43
1      3      52                    10    1E-96
                    gi|56159943|gb|AAV80783.1|
1      3      52                     7    1E-125
                    gi|22164320|gb|AAM93665.1|AF483743_1
1      3      52                     7    1E-104
                    gi|22164318|gb|AAM93664.1|AF483742_1
1      3      52                     4    1E-107
                    gi|22164278|gb|AAM93644.1|AF483722_1
4      3      52                    16    1E-136
                    gi|22164276|gb|AAM93643.1|AF483721_1
1      3      52                     3    1E-122
                    gi|22164270|gb|AAM93640.1|AF483718_1
1      3      52                    10    1E-109
                    gi|22164268|gb|AAM93639.1|AF483717_1
4      3      52                     3    1E-126
                    gi|15428310|gb|AAK97825.1|AF209922_1
1      3      52                     2    2E-90
                    gi|15428306|gb|AAK97823.1|AF209920_1
4      3      52                     8    1E-129
                    gi|15428302|gb|AAK97821.1|AF209918_1
1      3      52                     3    1E-61
                    gi|15428298|gb|AAK97819.1|AF209916_1
1      3      52                     5    1E-133
                    gi|15428292|gb|AAK97816.1|AF209913_1

1      0      1     IS-18-24-clu2173      3E-46
1     232     1                    6      4E-72
                    gi|56159959|gb|AAV80791.1|
1     196     1     IS-18-24-clu3403      3E-59
1      0      1     IS-18-24-clu2172      6E-41



1     231     1                    3      5E-38
                    gi|56159961|gb|AAV80792.1|

1     16      2     ISN-L582       4     1E-59
1     16      2     IS-18-24-clu1052     5E-71



13   1E-124
 2   1E-114
 4   1E-117
 2   1E-135
 1   1E-109

1     63      1     ISJ-ISPL-P8-G61      1E-88
1     34      1     ISN-L70      12      6E-69
2   24   2                   9
               ISNU-L-ISNU-495A     6E-53

1   5    7     ISNU-L-ISNU-51 5      2E-96
1   5    7     ISNU-L-ISN-50 3       7E-97
1   5    7     ISNU-cluster-522     1E-101
1   5    7     IS-18-24-clu5132      2E-98
1   5    7                    4      1E-97
               gi|8896135|gb|AAF81253.1|AF270496_1
1   5    7     gi|15428346|gb|AAK97827.1|
1   5    7                    5      4E-93
               gi|15428300|gb|AAK97820.1|AF209917_1

1   1    187                   29
               IS-6-12-J-cluster-62  8E-82
1   1    187                    1
               IS-6-12-J-cluster-96  1E-48
1   1    187                    1
               IS-6-12-J-cluster-97  6E-48
1   1    187   IS-18-24-clu28 1      5E-64
1   1    187   ISJ-ISPL_P7_G12  4    1E-66
1   1    187   ISNU-cluster-393 1    2E-67
1   1    187   IS-18-24-clu27 3      1E-66
1   1    187   IS-18-24-clu3761      3E-66
1   1    187   IS-18-24-clu31 2      5E-61
1   1    187   IS-18-24-clu1234      2E-69
1   1    187                    1
               IS-6-12-J-cluster-226 6E-69
1   1    187   IS-18-24-clu23114     3E-71
1   1    187   IS-18-24-clu2333      6E-72
1   1    187   IS-18-24-clu50b6      5E-45
1   1    187   ISNU-cluster-489 1    7E-68
1   1    187   IS-6-12L-5-33 4       3E-67
1   1    187   IS-18-24-47     25    3E-67
1   1    187   ISJ-ISPL_P7_G8   1    2E-68
1   1    187   IS-18-24-clu50 11     3E-68
1   1    187   ISN-L-85         6    3E-72
1   1    187   ISN-L-107        5    2E-71
1   1    187                    7    9E-68
               gi|22164314|gb|AAM93662.1|AF483740_1
1   1    187                    2    8E-69
               gi|56159937|gb|AAV80780.1|
1   1    187                    2    1E-72
               gi|56159949|gb|AAV80786.1|
1   1    187   ISN-L-68         3    1E-37
1   1    187   ISJ-ISPL_P5_G9   4    4E-75
1   1    187   IS-6-12-J-cluster-200
1   1    187                   14
               IS-6-12-J-cluster-295 1E-75
1   1    187   ISJ-ISPL_P9_E5   1    5E-52
1   1    187                    1
               IS-6-12-J-cluster-511 2E-55
1   1    187   IS-6-12L-19      5    9E-62
1   1    187   IS-18-24-clu24 8      4E-63
1   1    187                    2    1E-23
               gi|22164304|gb|AAM93657.1|AF483735_1
1   1    187                    1    6E-59
               gi|56159919|gb|AAV80771.1|

1   1    187   IS-6-12L-70     2     3E-55
1   1    187                   8
               IS-6-12-J-cluster-588 3E-91
1   1    187   IS-18-24-clu3621      3E-92
1   1    187                   1
               IS-6-12-J-cluster-91  6E-96
1   1    187                   3
               IS-6-12-J-cluster-90  1E-104
1   1    187                   4     1E-103
               gi|56159933|gb|AAV80778.1|
1   1    187   ISNU-cluster-3582     9E-99
1   1    187   ISN-L-167       3     1E-70
1   1    187                   3     7E-67
               gi|56159925|gb|AAV80774.1|
1   1    187                   1     1E-19
               gi|12002008|gb|AAG43147.1|AF061845_1
1   1    187   ISNU-L-ISN-77 3       6E-99



1   30   2                    3      2E-84
               gi|22164288|gb|AAM93649.1|AF483727_1
1   30   2                    3     1E-109
               gi|56159953|gb|AAV80788.1|

1   17   2     ISN-L-110    8       2E-73
1   17    2                    2      1E-75
                gi|22164282|gb|AAM93646.1|AF483724_1

1   15    2     ISN-L181A       1         2E-66
1   15    2     ISN-L181B       3         7E-57

1   67     1    ISJ-ISPL_P7_G3  12        9E-69
1   103    1                     1
                IS-6-12-J-cluster-211     2E-96
1   109    1                     1
                IS-6-12-J-cluster-385     2E-46
1    1    187                    4
                IS-6-12-J-IS612-484       1E-83
1    1    187                    4
                IS-18-24-clu102salivary   3E-72
2   19     2    ISJ-ISPL_P3_H12  1        2E-61
2   19     2    ISJ-ISPL_P3_H12  3        1E-60

1   1     187                  1      3E-67
                gi|56159957|gb|AAV80790.1|
1   1     187   IS-18-24-clu1443      6E-78
1   1     187   is-all-704     5      2E-79



1   7     3     IS-18-24-clu96 5      5E-75
1   7     3     ISJ-ISPL_P7_F123      6E-75
1   7     3                    9      3E-76
                gi|56159931|gb|AAV80777.1|

1   31    2                    6     1E-118
                gi|15428304|gb|AAK97822.1|AF209919_1
1   31    2                    4     1E-112
                gi|56159927|gb|AAV80775.1|

1   20    2     ISJ-ISPL_P8_D4  2         1E-106
1   20    2                     4
                IS-6-12-J-cluster-330     1E-111

1   1     187                   1
                IS-6-12-J-cluster-41      8E-38
1   1     187                   4
                IS-6-12-J-cluster-42      1E-48

1   22    2                     2
                IS-6-12-J-cluster-399     2E-93
1   22    2     ISNU-cluster-4823         1E-86

1   238   1                    2     1E-124
                gi|22164290|gb|AAM93650.1|AF483728_1

1   14    3                    4
                ISNU-cluster-162          1E-120




1   65    1                  2
                ISJ-ISPL_P2_B3            6E-49

1   129    1                     3
                IS-6-12-J-IS612-504   4E-58
1   116    1                     2
                IS-6-12-J-cluster-442 4E-20
1   97     1                     1
                IS-6-12-J-cluster-165 3E-13
1   104    1                     1
                IS-6-12-J-cluster-263 3E-17
1   146    1    ISNU-cluster-283
1   110    1                     1
                IS-6-12-J-cluster-390 5E-25
1   105    1                     1
                IS-6-12-J-cluster-297 5E-27
1   83     1    IS-6-12L-34     26    5E-34
1   147    1    ISNU-cluster-333 1    1E-24
1    1    187   IS-6-12-J-cluster-105
1    1    187   is-all-523
1   236    1                     1    6E-32
                gi|22164300|gb|AAM93655.1|AF483733_1
1   102    1                    20
                IS-6-12-J-cluster-207 5E-29
1   106    1                     1
                IS-6-12-J-cluster-328 3E-37
1    1    187   ISNU-L-IS-283A4       4E-25
1   150    1    ISNU-cluster-525 1    9E-35
1   113    1                     1
                IS-6-12-J-cluster-423 2E-31
1   188    1    ISUFJ-cluster-3101    7E-45
1   66     1    ISJ-ISPL_P6_G3   1    4E-43
1   121    1                     1
                IS-6-12-J-cluster-534 3E-44
1   221    1    is-all-335      15    2E-62
1   126    1                     1
                IS-6-12-J-cluster-602 5E-10
1    1    187   ISJ-ISPL_P6_E90 1     2E-62
1   96     1                     1
                IS-6-12-J-cluster-139 7E-55
1   153    1    ISUFL108         2    6E-63
1   230    1                     1    2E-58
                gi|56159963|gb|AAV80793.1|
1    1    187   IS-18-24-34     17    2E-70
1    3    52                     2    2E-76
                gi|56159945|gb|AAV80784.1|
1   195    1    IS-18-24-clu1472      8E-71
1   28     2    is-all-465       3    5E-83
1   108    1                     1
                IS-6-12-J-cluster-370 7E-42
1    1    187   ISN-L179         2    1E-64
1   101    1                     3
                IS-6-12-J-cluster-204 8E-89
1   233    1                     3    1E-100
                gi|56159951|gb|AAV80787.1|
1   192    1    ISUFJ-cluster-89 7    2E-94
1    1    187                    1
                IS-6-12-J-cluster-218 1E-112
1   190    1    ISUFJ-cluster-3331    1E-122
1   127    1                     2
                IS-6-12-J-cluster-69  2E-75
1   130    1                     6
                IS-6-12-J-IS612-525   1E-111
1   120    1                     2
                IS-6-12-J-cluster-523 1E-107
1   144    1    ISNU-cluster-102 4    1E-150
1   125    1                     6
                IS-6-12-J-cluster-593 2E-95
1   235    1                     3    2E-64
                gi|56159929|gb|AAV80776.1|
1   25     2                    14    1E-158
                gi|51243761|gb|AAT99573.1|
                       Link to nucleotide     Link to      First               SigP    Cleavage                    Mature
     Seq name              sequence            NCBI      residue   Seq size   Result   Position    MW       pI      MW
Transposable Element
ISUFJ-cluster-253                       67083861
                  ISUFJ-cluster-253possible                M         254       SIG       17-18    28.07    4.83    26.004
Conserved of unknown function
IS-6-12-J-cluster-114 IS-6-12-J-cluster-114   67084105     M         244      SIG        21-22    27.583   4.96    25.282
ISUFL75               ISUFL75unknown          67083799     M         132      CYT                 14.524   10.17
ISUFL127              ISUFL127                67083841     M         117      ANC                 13.359    9.7
ISUFL126              ISUFL126                67083843     M         142      CYT                 16.183    7.8
ISUFL105              ISUFL105                67083853     M         76       CYT                  8.827   6.26
ISNU-L-ISNU-352       ISNU-L-ISNU-352         67083867     M         105      CYT                 11.939   10.39
ISNU-L-ISNU-305       ISNU-L-ISNU-305         67083871     M         59       ANC                  6.928   10.64
ISNU-L-ISN-83         ISNU-L-ISN-83           67083877     M         141      CYT                 15.499    10
ISNU-L-ISN-146        ISNU-L-ISN-146          67083883     M         185      CYT                 20.438   9.38
ISN-L111              ISN-L111                67083935     M         99       ANC                 10.772   4.75
is-all-489            is-all-489              67083969     M         85       ANC                  9.594    6.7
is-all                is-all                  67084005     M         158      SIG        38-39     16.93    8.7    12.964
IS-6-12-J-cluster-361 IS-6-12-J-cluster-361   67084091     M         202      SIG        20-21    23.302   9.89    21.021
IS-6-12L-454          IS-6-12L-454            67084023     M         37       ANC                  4.07    6.51
IS-6-12L-315          IS-6-12L-315            67084031     M         91       CYT                  9.579   4.67
gi|55736017           gi|55736016             55736017     M         74       CYT                  8.388   9.74
IS-18-24-clu397       IS-18-24-clu397         67084107     M         93       CYT                 10.668   9.25
gi|55736027           gi|55736026             55736027     M         151      CYT                 17.854   4.93
Transporter
gi|55736029           gi|55736028             55736029     M         194       CYT                21.412   9.23
Transcription machinery
ISUFL68             ISUFL68             67083805           M         272       CYT                30.445   5.38
ISUFL133            ISUFL133            67083837           M         220       CYT                24.391   4.79
ISNU-L-ISN-96       ISNU-L-ISN-96       67083873           M         85        CYT                 9.931   6.04
ISN-L-169                               67083917
                    ISN-L-is_5_100_92_169_CLU              M         162       CYT                18.509   4.39
is-all-clu546       is-all-clu546       67083957           M         154       CYT                16.963   5.47
Transcription factor
IS-6-12-J-cluster-439 IS-6-12-J-cluster-439 67084085       M         257       SIG       34-35    28.341   8.88    24.697
Lysosomal
IS-6-12-J-cluster-407 IS-6-12-J-cluster-407 67084089       M         225       BL        37-38    24.466   7.42    20.388
Signal transduction/regulation
ISUFJ-cluster-325    ISUFJ-cluster-325   67083859          M         79        CYT                 9.053   6.97
ISN-L-209                                67083907
                     ISN-L-is_5_100_92_209_CLU             M         107       CYT                11.615   7.06
gi|22164280          gi|22164279         22164280          V         390       IND                42.332   6.23
Translation machinery
ISUFL99             ISUFL99                   67083787     M         112       CYT                12.497   9.71
ISUFL92             ISUFL92                   67083791     M         189       CYT                21.821   10.28
ISUFL81             ISUFL81                   67083793     M         156       CYT                18.102   9.83
ISUFL76             ISUFL76                   67083797     M         71        CYT                 8.316   10.05
ISUFL72           ISUFL72             67083803   M   92    CYT   10.304   10.49
ISUFL56           ISUFL56             67083811   M   165   CYT    17.85   9.23
ISUFL49           ISUFL49             67083815   M   121   CYT   13.688   9.61
ISUFL48           ISUFL48             67083817   M   209   CYT   24.015   10.51
ISUFL46           ISUFL46             67083819   M   114   CYT   11.477   4.76
ISUFL28           ISUFL28             67083827   M   269   CYT   30.705   10.69
ISUFL26           ISUFL26             67083829   M   220   CYT   25.556   10.13
ISUFL22           ISUFL22             67083831   M   319   CYT   34.763   6.05
ISUFL21           ISUFL21             67083833   M   262   CYT    29.64   10.28
ISUFL129          ISUFL129            67083839   M   81    CYT    9.439   10.28
ISUFL114          ISUFL114            67083847   M   136   CYT   15.828    9.5
ISUFL109          ISUFL109            67083849   M   141   CYT   16.399   11.5
is-all-clu554     is-all-554          67083951   M   185   CYT   21.352   10.56
is-all-538        is-all-538          67083965   M   56    CYT    6.678    9.8
is-all-456        is-all-456          67083973   M   204   CYT   24.338   11.47
is-all-441        is-all-441          67083977   M   130   CYT   14.927   10.01
is-all-416        is-all-416          67083983   M   117   CYT   13.545   10.52
is-all-399        is-all-399          67083987   M   251   CYT   29.562   10.97
is-all-398        is-all-360          67083989   M   150   CYT   16.542   10.01
is-all-397        is-all-397          67083991   M   198   CYT   23.458   11.37
is-all-378        is-all-378          67083999   M   270   CYT    30.18   9.75
IS-6-12L-99       IS-6-12L-99         67084007   M   187   CYT   21.447   9.88
IS-6-12L-94       IS-6-12L-94         67084009   M   149   CYT   17.286   10.04
IS-6-12L-89       IS-6-12L-89         67084011   M   100   CYT    11.45   11.96
IS-6-12L-68       IS-6-12L-68         67084015   M   130   CYT   14.974   9.83
IS-6-12L-52       IS-6-12L-52         67084019   M   161   CYT   18.833   10.73
IS-6-12L-50       IS-6-12L-50         67084021   M   84    ANC    9.479   9.57
IS-6-12L-37       IS-6-12L-37         67084025   M   119   CYT   13.624   11.23
IS-6-12L-35       IS-6-12L-35         67084027   M   146   CYT   16.593   11.41
IS-6-12L-32       IS-6-12L-32         67084029   M   140    BL   14.786   10.48
IS-6-12L-311      IS-6-12L-311        67084033   M   127   CYT   14.929   10.51
IS-6-12L-30       IS-6-12L-30         67084035   M   156   CYT   18.122   11.19
IS-6-12L-293      IS-6-12L-293        67084037   M   110   CYT   12.761   11.1
IS-6-12L-29       IS-6-12L-29         67084039   M   151   CYT   17.225   10.69
IS-6-12L-28       IS-6-12L-28         67084041   M   151   CYT   16.132   10.31
IS-6-12L-260      IS-6-12L-260        67084043   M   116   CYT   13.513   10.34
IS-6-12L-242      IS-6-12L-242        67084047   M   123   CYT   14.354   11.58
IS-6-12L-223      IS-6-12L-223        67084049   M   151   CYT   17.351   11.38
IS-6-12L-22       IS-6-12L-22         67084051   M   217   CYT    24.57    9.8
IS-6-12L-136      IS-6-12L-136        67084053   M   188   CYT    21.62   11.67
IS-6-12L-109      IS-6-12L-109        67084057   M   198   CYT   22.941   10.11
IS-18-24-clu110   IS-18-24-clu110     67084113   M   51    CYT    6.373   12.55
ISUFL78           ISUFL78             67083795   M   169   CYT   18.649   6.94
ISUFL41           ISUFL41             67083821   M   209   CYT    23.3    9.76
ISUFL107          ISUFL107            67083851   M   155   CYT   17.661   4.74
ISN-L-99                              67083893
                  ISN-L-is_5_100_92_99_CLU       M   148   CYT   16.807   10.54
ISN-L-89                              67083895
                  ISN-L-is_5_100_92_89_CLU       M   111   CYT   12.416   10.2
ISN-L-86                              67083897
                  ISN-L-is_5_100_92_86_CLU       M   105   CYT   12.499   10.55
ISN-L-49                              67083901
                  ISN-L-is_5_100_92_49_CLU       M   152   CYT   17.718   10.87
ISN-L-180                             67083913
                  ISN-L-is_5_100_92_180_CLU      M   120   CYT   13.488   11.01
ISN-L-141                             67083925
                  ISN-L-is_5_100_92_141_CLU      M   148   CYT   16.645   10.1
ISN-L-140                             67083927
                  ISN-L-is_5_100_92_140_CLU      M   176   CYT   20.858   10.76
ISN-L-128                             67083929
                  ISN-L-is_5_100_92_128_CLU      M   132   CYT   14.393   6.51
ISN-L-126                             67083931
                  ISN-L-is_5_100_92_126_CLU      M   83    CYT    9.257   5.57
ISN-L-101                             67083939
                  ISN-L-is_5_100_92_101_CLU      M   120   CYT   13.646   10.69
is-all-clu550     is-all-clu550       67083953   M   87    CYT   10.719   10.15
is-all-382        is-all-382          67083997   M   318   CYT   35.995   7.06
is-all-360        is-all-360          67083989   M   297   CYT   16.655   10.05
is-all-360        is-all-360          67083989   K   151   CYT   16.663   10.05
IS-6-12L-87       IS-6-12L-87         67084013   M   64    ANC    7.267   10.29
IS-6-12L-111      IS-6-12L-111        67084055   M   192   CYT    22.59   10.62
IS-6-12L-102      IS-6-12L-102        67084061   M   134   CYT    14.6    9.87
IS-6-12L-100      IS-6-12L-100        67084063   M   25    IND    3.463   12.61
IS-6-12-J-cluster-577 IS-6-12-J-cluster-577 67084073       M        309   CYT           33.943   8.12
IS-6-12-J-cluster-444 IS-6-12-J-cluster-444 67084083       M        119   SIG   19-20    13.79   9.82    11.475
Proteasome machinery
ISUFL74           ISUFL74             67083801             M        234   CYT           26.312   9.62
ISN-L-109                             67083937
                  ISN-L-is_5_100_92_109_CLU                M        155   CYT           17.959   8.91
is-all-426        is-all-426          67083981             M        156   CYT           17.948   9.71
IS-6-12L-25       IS-6-12L-25         67084045             M        123   CYT           13.793   9.66
Post-translation modification machinery
ISUFJ-cluster-392     ISUFJ-cluster-392     67083855       M        307   CYT           35.683   5.47
ISUFJ-cluster-365     ISUFJ-cluster-365     67083857       M        320   CYT           36.786   7.27
is-all-450            is-all-450            67083975       M        222   SIG   20-21    25.42    6.5    23.14
IS-6-12-J-cluster-51 IS-6-12-J-cluster-51   67084077       M        242   CYT           27.494   6.16
IS-6-12-J-cluster-235 IS-6-12-J-cluster-235 67084093       M        358   SIG   20-21   41.372   5.98    39.129
IS-6-12-J-cluster-143 IS-6-12-J-cluster-143 67084101       Y        452   CYT           51.617   6.04
is-all-553            is-all-553            67083963       M        100   ANC           11.301   9.87
ISUFL301              ISUFL301              67083823       M        171   SIG   31-32   18.761   9.32    15.136
IS-6-12-J-cluster-190 IS-6-12-J-cluster-190 67084095       M        165   CYT           18.104   9.24
ISUFL522              ISUFL522              67083813       M        120   CYT           13.115   8.46
ISN-L-168                                   67083919
                      ISN-L-is_5_100_92_168_CLU            M        114   CYT            12.77    8.4
is-all-clu549         is-all-549            67083955       M        172   CYT           19.293   7.07
IS-6-12-J-cluster-578 IS-6-12-J-cluster-578 67084071       M        323   SIG   21-22    35.18   4.84    32.459
IS-6-12-J-cluster-170 IS-6-12-J-cluster-170 67084099       M        168   SIG   23-24    18.18   4.51    15.547
IS-18-24-clu117       IS-18-24-clu117       67084109       M        137   CYT           15.278   7.72
gi|56159969           gi|56159968           56159969       M        335   SIG   29-30   37.795   9.81    34.334
gi|55736025           gi|55736024           55736025       M        171   CYT           19.756   5.98
gi|55736021           gi|55736020           55736021       M        107   CYT            12.43   4.55
gi|22164292           gi|22164291           22164292       M        376   ANC           41.474   4.49
Protein export machinery
ISUFL65               ISUFL65                 67083809     M        191   SIG   18-19   21.465    6.9    19.322
ISNU-L-ISNU-95        ISNU-L-ISNU-95          67083863     M        155   SIG   28-29   17.843   5.53    14.654
ISNU-L-ISNU-94        ISNU-L-ISNU-94          67083865     M        155   SIG   27-28    17.89   5.34    14.783
ISNU-L-ISN-157        ISNU-L-ISN-157          67083881     M        107   CYT           12.486   9.52
is-all-429            is-all-429              67083979     M        166   SIG   26-27   18.703   5.02    15.674
IS-6-12L-106          IS-6-12L-106            67084059     M        166   CYT            19.42   9.16
IS-6-12-J-cluster-84 IS-6-12-J-cluster-84     67084067     M        179    BL   25-26   20.323    8.5    17.396
IS-6-12-J-cluster-461 IS-6-12-J-cluster-461   67084079     M        171   SIG   21-22   18.834   6.07    16.443
IS-18-24-clu114       IS-18-24-clu114         67084111     M        181   CYT           20.561   6.15
Oxidant metabolism
ISUFL293           ISUFL293                   67083825     M        154   CYT           15.659   6.09
IS-6-12L-589       IS-6-12L-589               67084017     M        162   CYT           18.374   9.04
Nuclear regulation
ISNU-L-ISN-167          ISNU-L-ISN-167        67083879     M        107   CYT           11.351    9.8
ISN-L369                ISN-L369              67083903     M        69    CYT            8.142   9.16
ISN-L-157                                     67083921
                        ISN-L-is_5_100_92_157_CLU          M        103   CYT           11.373   11.36
ISN-L-112                                     67083933
                        ISN-L-is_5_100_92_112_CLU          M        124   CYT           13.831   10.52
IS-6-12-J-cluster-183   IS-6-12-J-cluster-183 67084097     M        188   CYT            21.7    8.24
gi|55736031             gi|55736030           55736031     M        231   CYT           26.614   5.78
Nucleic acid metabolism
ISUFL125              ISUFL125               67083845       M       176   CYT           20.049   4.44
                                             67084087       M
IS-6-12-J-cluster-432 IS-6-12-J-cluster-432nucleoside-diphosphate   170   SIG   16-17   19.393   8.97    17.57
Energy metabolism
IS-6-12L-589            IS-6-12L-589        67084017       M        162   CYT           18.374   9.04
ISN-L-197                                   67083911
                        ISN-L-is_5_100_92_197_CLU          M        99    SIG   19-20   10.963   9.08     8.726
ISUFL97                 ISUFL97             67083789       M        282   SIG   29-30   31.895   9.03    28.715
ISUFL67                 ISUFL67             67083807       E        198   CYT           20.631   9.55
ISUFL47                 ISUFL47              3452460       M        258   ANC           30.839   9.17
ISUFL14                 ISUFL14             67083835       M        299   CYT            32.93   9.86
ISNU-L-ISNU-313         ISNU-L-ISNU-313     67083869       M        81     BL   29-30    9.434   9.75    6.129
ISNU-L-ISN-86           ISNU-L-ISN-86ATP    67083875       M        172   CYT           20.109   5.39
ISNU-L-ISN-103          ISNU-L-ISN-103      67083887       M        54    ANC            6.306   8.89
ISN-L-61                                    67083709
                        ISN-L-is_5_100_92_61_CLU           M        142   ANC           16.973   10.51
ISN-L-51                                      67083899
                        ISN-L-is_5_100_92_51_CLU         M   152   CYT            15.6    10.03
ISN-L-41                ISN-L-is_5_100_92_41_CLU         M   220   CYT           25.668   9.83
ISN-L-23                ISN-L-is_5_100_92_23_CLU         M   193   CYT           22.422   5.68
ISN-L-22                ISN-L-is_5_100_92_22_CLU         M   512   ANC           57.685   7.95
ISN-L-216               ISN-L-is_5_100_92_216 67083905   M   85    CYT            9.982   9.66
ISN-L-208                                     67083909
                        ISN-L-is_5_100_92_208_CLU        M   109   CYT           12.073    9.6
ISN-L-155                                     67083923
                        ISN-L-is_5_100_92_155_CLU        M   55    CYT            6.126   10.17
is-all-clu620           is-all-clu620         67083945   M   264   SIG   16-17   30.623   9.05    28.502
IS-all-clu578           IS-all-clu578         67083947   M   107   CYT           12.707   9.96
is-all-clu571           is-all-571            67083949   M   166   CYT           17.624   5.02
is-all-611              is-all-611            67083959   M   97    CYT            10.43   9.74
is-all-564              is-all-564            67083961   M   82    CYT             9.7    9.87
is-all-507              is-all-507            67083967   M   179   CYT           20.767   9.54
is-all-484              is-all-484            67083971   M   164   CYT            17.87   9.91
is-all-413              is-all-413            67083985   M   89    CYT           10.218    9.7
is-all-395              is-all-395            67083993   M   76    SIG   31-32    8.438   9.47    4.917
is-all-393              is-all-393            67083995   M   122   CYT           13.994   9.16
IS-6-12-J-IS612-63                            67084065
                        IS-6-12-J-IS612-63probable       M   312   SIG   21-22   33.145   9.03    30.593
IS-6-12-J-cluster-66    IS-6-12-J-cluster-66  67084069   M   129   CYT           14.269   9.83
IS-6-12-J-cluster-451   IS-6-12-J-cluster-451 67084081   L   165   IND           17.213     8
IS-6-12-J-cluster-132   IS-6-12-J-cluster-132 67084103   M   96    CYT           10.587   10.01
gi|55736033             gi|55736032           55736033   M   322   SIG   18-19   35.744   9.93    33.801
gi|22164298             gi|22164297           22164298   M   409   SIG   19-20   47.757   6.44    45.638
ISNU-cluster-364        ISNU-cluster-364      67083891   M   108   CYT           11.869   6.26
gi|56159967             gi|56159966           56159967   M   321   SIG   22-23   35.287   4.96    32.718
Immunity related
ISJ-ISPL-P2-F6          ISJ-ISPL-P2-F6       67083943    C   148   CYT           16.562   9.86
Cuticle and Extracellular matrix
ISJ-ISPL-P4-E5       ISJ-ISPL-P4-E5          67083941    A   156   IND           15.317   9.27
gi|50363178          gi|50363177             50363178    M   320   SIG   18-19    31.77   9.44    29.843
gi|56159947          gi|56159946             56159947    M   117   SIG   16-17   12.447    4.4    10.585
Cytoskeletal proteins
ISNU-L-ISN-145        ISNU-L-ISN-145        67083885     M   147   CYT           16.523   4.49
IS-6-12-J-cluster-559 IS-6-12-J-cluster-559 67084075     M   173   CYT           19.438   4.67
                                                                            ----------------------------------------------------------------------------------------




                                                                                                              PROLINE
                                                                                                              GLYCINE
                                                                                                                 RICH
                                                                                                              PEPTIDE
                                                            Number                                            S motif G-
                                                               of                                              [SKQN]-           GPP
                                                            possible         Predicted                        [ST]-X-P-        Platelet
                                                            HO-Pro           Tyr-SO4 -            RGD         C-X(3)-P-        collagen
       No. glyc   % Ser +    Percent    Percent            [LPAE]-P- Number   Prosite           flanked       G-X(2)-C-        binding
pI      sites       Thr        Gly        Pro      Pro+Gly     G     of PG's   rules             by Cys         X(8)-P.        domain


4.77      0       8.661417 6.692914     5.905512 12.59843      1        2                                                    GPP-> GPP 84



4.91      5       15.16393   5.327869   5.327869   10.65574             1
          6       24.24242   4.545455   3.030303   7.575758             1
          0       17.94872    9.40171       0       9.40171
          1       10.56338   6.338028   3.521127   9.859155             1
          0       17.10526   2.631579       0      2.631579
          0       8.571429   1.904762   5.714286   7.619048
                  8.474576                             0
          0       12.05674   9.929078   3.546099   13.47518
          0       14.59459   7.027027   4.324324   11.35135    1        1
          3       14.14141   9.090909   11.11111   20.20202                          1
          0       9.411765   7.058824   3.529412   10.58824
7.74      3       6.962025   7.594937   6.962025   14.55696    1        1
9.85      0       12.37624   6.435644   6.930693   13.36634             1
          0       8.108108   5.405406   2.702703   8.108109
          1       14.28571   5.494505   4.395605    9.89011                          1
          0       5.405405   1.351351   5.405406   6.756757
          2       9.677419   1.075269   10.75269   11.82796
          0       8.609272   1.324503   2.649007    3.97351

          0       14.43299 8.762887     4.639175 13.40206

          0         12.5     6.25       4.044117   10.29412             1
          1       11.36364 5.454545         5      10.45455             2
          0       7.058824 7.058824     4.705883   11.76471                                                                  GPP-> GPP 76
          0       9.876543 3.08642      5.555555   8.641975
          0       14.28571 8.441559     3.246753   11.68831

8.91      7       14.39689 5.058366     8.171206 13.22957                            1

5.92      0       9.777778 7.111111     2.222222 9.333333                            1

          1       11.39241 5.063291     2.531646 7.594937
          5       13.08411 6.542056     8.411215 14.95327
          1       15.89744 5.897436     3.589744 9.48718       1        1            2

          0       13.39286   7.142857   3.571429   10.71429             1
          1       11.64021   5.820106   2.645503   8.465609             1
          0       5.769231   7.692307   8.974359   16.66667    2        2
          0       9.859155   1.408451   5.633803   7.042254    1        1
0   18.47826   8.695652       0      8.695652
0   12.12121   7.878788   7.272727   15.15152
2   17.35537   4.958678   5.785124    10.7438       1
0   10.04785    8.61244   3.349282   11.96172       1
1    8.77193    13.1579   5.263158   18.42106       1
0   7.063197   4.460967   5.947956   10.40892
0   5.909091   7.727273   5.454545   13.18182       1   1
0   10.03135   6.583072   5.015674   11.59875
0    11.0687   8.396947   5.725191   14.12214       1
0   8.641975   4.938272   2.469136   7.407408
0   8.088235   2.941176   2.941176   5.882352
0   14.89362   4.255319   4.255319   8.510638
0   8.108108   4.864865   4.864865    9.72973           1
0   3.571429   10.71429   3.571429   14.28572   1   1
0   7.843137   7.843137   3.921569   11.76471
0   8.461538   9.230769   2.307692   11.53846
0   8.547009   5.982906   3.418803   9.401709
3   6.374502   5.577689   5.179283   10.75697
0       10     6.666667   5.333333       12
0   4.545455   3.535353   2.020202   5.555555   1   1
1   11.48148   8.888889   2.962963   11.85185       1   1
0   6.951872   10.16043   3.743315   13.90375   1   2
0   8.724832    7.38255   5.369128   12.75168       1
1       16         10         2          12
0       10     6.153846   6.153846   12.30769       1
0   4.347826   9.316771   5.590062   14.90683
0   13.09524   5.952381   7.142857   13.09524       1
    14.28571                              0         2
0    8.90411   7.534246   5.479452    13.0137       1
0   6.428571   12.14286       5      17.14286
0   11.81102   5.511811   3.149606   8.661417
0   9.615385   6.410256   5.128205   11.53846
0   7.272727   7.272727   2.727273       10
0   11.92053   5.960265   4.635762   10.59603
1   11.92053   11.25828   5.298013   16.55629   1   2
0   9.482759   6.034483   2.586207    8.62069
0   7.317073   4.065041   3.252033   7.317074
0   9.933775    3.97351   3.311258   7.284768
1   9.677419   3.225806   4.608295   7.834101   1   1       GPP-> GPP 210
0   7.978723   7.446808   5.319149   12.76596   1   2
0   10.60606   2.525253   3.535353   6.060606       1
0   7.843137   1.960784   3.921569   5.882353
3   11.83432   7.142857   6.547619   13.69048           1
6    13.8756   5.263158   3.349282    8.61244
5   13.54839    5.16129   4.516129   9.677419           1
0   6.756757   12.16216   4.054054   16.21621       2
3   15.31532   6.306306   2.702703   9.009009
0   7.619048   8.571428   2.857143   11.42857
0   9.868421   7.236842   1.973684   9.210526
2       10     3.333333   8.333333   11.66667
1   6.756757   8.108109   4.054054   12.16216   1   1
0   11.36364   2.840909     6.25     9.090909
0   6.060606   7.575758   0.757576   8.333334
0   10.84337   7.228916   3.614458   10.84337
0   10.83333   10.83333      2.5     13.33333
0   5.747126   3.448276   2.298851   5.747127
0   15.72327   5.974843   2.830189   8.805032
0   9.933775   7.407407   2.356902   9.764309
0   9.933775   7.407407   2.356902   9.764309
0     9.375       6.25      6.25        12.5
1   6.770833   6.770833   2.604167     9.375
0   11.19403   8.955224   2.985075    11.9403
0        4          0         0           0
       4   10.35599   4.20712    8.090615 12.29774         2   1
9.67       13.44538                           0

       1   9.401709   5.982906   4.700855   10.68376
       0   7.741935   3.225806    9.67742   12.90323
       0   9.615385   6.410256   3.846154   10.25641
       0   8.943089   8.130081   4.065041   12.19512       1

       2   13.68078   3.908795   4.234528   8.143323
       0    13.125      5.625      4.375        10         1
6.49   0   11.71171   3.603604   4.504505   8.108109       1   1
       0   9.504132   4.545455   4.545455    9.09091           1
5.93   0   10.61453   3.910614   4.748603   8.659217       1   2
       0   11.06195   5.973451   5.309734   11.28319           1
       1      12          7          7          14
8.99   2   15.78947   5.847953   2.923977    8.77193
       0   11.51515   13.33333   4.242424   17.57575   1   1   1
       0   9.166667     12.5     9.166667   21.66667       3
       1   14.03509   7.017544   2.631579   9.649123
       2   11.62791   6.976744   6.976744   13.95349
4.72   0   11.45511   7.120743    3.71517   10.83591       1
4.44   0   13.09524   8.928572   2.380952   11.30952
       0   10.21898   5.109489   4.379562   9.489051
9.86   0   12.23881   5.671642   4.179104   9.850746           1   GPP-> GPP 242
       1   14.03509   3.508772   7.017544   10.52632
       0   7.476636   2.803738   2.803738   5.607476
       0    14.3617   7.446808   4.521276   11.96808           3   GPP-> GPP 290



7.19   0   11.51832   6.282722   3.141361 9.424083     1   2
5.41   0   7.741935   3.225806   0.645161 3.870967
 5.2   0   7.741935   3.225806   0.645161 3.870967
       0   13.08411   6.542056   0.934579 7.476635
4.84   0   10.84337   5.421687   1.807229 7.228916
       4   7.831325   4.819277   7.831326  12.6506     1   2
8.11       16.20112                           0
6.08   0   13.45029   5.847953   2.339181 8.187134         1
       0   10.49724   7.734807   1.657459 9.392266             1

       1   14.93506 16.23377     4.545455 20.77923
       2   9.876543 7.407407     4.320988 11.7284          1   2

       0   10.28037   14.01869   3.738318   17.75701       1       GPP-> GPP 96
       0   14.49275   7.246377   2.898551   10.14493           2
       0   8.737864   16.50485   0.970874   17.47572
       0   17.74194   4.032258   4.032258   8.064516   1   1
       3   9.042553   5.851064   5.319149   11.17021       1
       0   10.82251   4.329004   3.030303   7.359307

       1   10.22727 6.818182     3.977273 10.79546         1   2
 9     0   8.823529 7.647059     4.117647 11.76471         1

       2   9.876543   7.407407   4.320988  11.7284         1   2
9.08   1   9.090909   9.090909   5.050505 14.14141
8.76   0   11.70213   5.319149   6.028369 11.34752         2
       0   11.11111   13.70558   6.091371 19.79695         1
       0   15.11628   4.263566   3.488372 7.751938
           11.03679                           0
9.11   0   12.34568    6.17284   9.876543 16.04938
       0   6.976744   2.906977    8.72093 11.62791         1   2
       0   11.11111   9.259259   3.703704 12.96296
       0   14.08451   1.408451   3.521127 4.929578
        2    17.76316   9.868421   3.947368   13.81579
        0    16.81818   1.818182       5      6.818182
        0    16.58031   3.626943   5.181347    8.80829       2
        0    14.25781   8.398438   4.882813   13.28125   1   3
        0    7.058824   4.705883   7.058824   11.76471
        0    11.00917   11.92661   4.587156   16.51377       1
        2    14.54545   3.636364   3.636364   7.272728
7.89    1    8.712121   6.060606   4.545455   10.60606   2   2
        0    7.476636   6.542056   7.476635   14.01869
        0     12.6506   4.819277   4.819277   9.638554       1
        1    12.37113   6.185567   5.154639   11.34021
        0    6.097561   7.317073   6.097561   13.41463
             8.379888                             0              1
        0    14.02439   4.268293   4.268293   8.536586       1
        4    11.23596   5.617978   5.617978   11.23596
8.11    0    6.578947   10.52632   3.947368   14.47369   1   2   1
        0    7.377049   6.557377   5.737705   12.29508   1   1   1
8.77    5    17.30769    8.01282   2.884615   10.89744   1   3
        0    11.62791   11.62791   3.100775   14.72869
        3    14.54545   9.090909   5.454545   14.54545
        3    14.58333   8.333333   5.208333   13.54167
10.05   0     13.6646   8.695652   3.416149    12.1118   1   1
5.99    0    8.557457   4.156479   4.645477   8.801956           2
        0    12.03704    4.62963   6.481482   11.11111       1
4.86    9    13.70717   4.672897   8.411215   13.08411

        0    10.81081 10.81081     4.054054 14.86486         1

        18   14.74359 3.846154     8.974359 12.82051
9.43    21    14.6875   12.5         6.25     18.75
4.29     9   17.94872 5.982906     5.982906 11.96581         1

        0    11.56463 8.163265     2.040816 10.20408             1
        0    11.56069 8.092485     2.890173 10.98266
------------------------------------------------------------------------------------------------------------------------------------------MOTIFS SEARCHED TO FACILITATE GROUPING OF POLYPEPTID




                                                                              CONSER
                                                                                 VED
                   BASIC                                                      CATALYT MONOLA
                    TAIL                   Basic tail                             IC    RIS-2
                 PEPTIDE                   carboxy                            DOMAIN CYSTEIN                         MONOLA MONOLA               MONOLA
                 FAMILY -                  motif F-F-                            OF       E                SALP10      RIS-3     RIS-4              RIS-5   MONOLA
                 AMINOTE      Basic tail   X(3)-E-X-    IXOSTATI     SCO-      IXODES FRAMEW               motif L- cysteine cysteine             Cysteine RIS-6 cys
                  RMINAL       cysteine     C-F-Y-      N motif L- PONDIN METALL ORK C-                     X(3)-C- framewor framewor            framewor framewor
                 REGION       framewor      X(2)-G-     X-D-G-T-X- C-X(14)-C- OPROTE X(5)-C-                X(2)-P-  k C-X(8)- k C-X(10)-         k C-X(8)- k C-X(8)-
                 A-A-X(2)-    k C-X(14)-   X(2)-G-X-    C-G-X(4)- X(3)-C- ASES H- X(15)-C-                 X(2)-C-X- C-X(15)-C- C-X(3)-C-        C-X(18)-C- C-X(18)-C-
                 C-X-N-G-     C-X(3)-C-    C-X(2)-G-    C-X(2)-G- X(22)-C- E-L-A-H-N- X(8)-C-              G-X(6)-Y- X(7)-C-    X(23)-C-           X(5)-C-   X(5)-C-
                 T-R-P-X-      X(18)-C-    X-C-H-L-      X-C-X(7)- X(6)-C- L-G-C-Q- X(11)-C-               Y-X(4)-G- X(12)-C- X(10)-C-            X(12)-C- X(11)-C-
                     S.         X(9)-C.     X(6)-P          F.      X(4)-C. H-D-G-D. X(3)-C.                  C.      X(3)-C.    X(4)-C.           X(3)-C.   X(3)-C.
E GROUPING OF POLYPEPTIDES----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------




                                                               PUT-10
                                                              CYSTEIN                                                                                             THIS IS   THIS IS
                                                                  E          SMALL    SMALL                                8-CYS                                    FOR       FOR
                                                              FRAMEW        PEPTIDE PEPTIDE                               SIMILAR                                THROMB YGGC C-
                                    RGD     MICROPL            ORK OF       CYSTEIN CYSTEIN                                  TO                                     CYS    X(3)-I-Y-G-
                                  peptide USIN CYS            PUTATIV           E        E                       ANTIMIC SCORPIO                                 DOMAIN      G-C-G-
                   MONOLA            cys    FRAMEW            E 10 KDA      FRAMEW FRAMEW                         ROBIAL N TOXINS                                done on     X(11)C
                   RIS-7 C-      framewor ORK C-              PEPTIDE        ORK C- ORK C-              4-CYS-1 PEPTIDE C-X(18)-C-                                 03-25-   done on
                    X(8)-C-       k C-X(4)- X(12)-C-          C-X(11)-C-     X(3)-C-  X(4)-C- 5-CYS C- FRAMEW CONTAINI X(4)-C-                                    2005 C-    03-25-
                    X(16)-C-     C-X(5)-C- X(21)-C-            X(15)-C-      X(5)-C-  X(5)-C-  X(6)-C-  ORK C- NG GGY X(11)-C-                                   X(11)-C- 2005 C-
                    X(5)-C-      X(5)-C-X- X(4)-C-             X(3)-C-       X(3)-C-  X(4)-C-  X(24)-C-  X(8)-C- REPEATS X(8)-C-                                 X(14)-C- X(3)-I-Y-G-
                   X(11)-C-C-     C-X(11)-   X(5)-C-           X(12)-C-      X(2)-C-  X(2)-C-  X(11)-C- X(18)-C- G-G-Y-G- X(11)-C-C-                              X(3)-C-    G-C-G-
                    X(3)-C.           C.     X(25)-C.          X(6)-C.       X(10)-C. X(9)-C.  X(3)-C.   X(6)-C.   G-Y.    X(4)-C.                                X(24)-C. X(11)-C.
-----------------------------------------------------------------------------------------------------------------------------------------------------




                                                     TFPI-COX        10KDAPE
                        PCGP                          [QEN]-F-         P C-X-
                      ixostatin LPTS on              [AS]-[ST]-      [NDV]-X-
                      domain P- coxy                  X-[KDE]-       [IV]-[DE]-
                      C-G-P-X- [LVI]-P-               [KDE]-C-       X(2)-G-X- WC coxy WP coxy CPC coxy                                 Best match to NR                     Key
                       G-[QE]. [TS]-C.                   K.           [LI]-X-C. motif   motif    motif                                  protein database       E value      words


                                                                                                                                                              5E-019
                                                                                                                                   At3g55350 [Arabidopsis thaliana] >gnlARABIDOPSIS THALIANA UNKNOW

                                                                                                                                                                  7E-013
                                                                                                                                   similar to RPGR-interacting protein SIMILAR TO RPGR-INTERACTING R
                                                                                                                                                                  7E-011 SIMILAR TO MELLIFERA PREDICTE
                                                                                                                                   similar to ENSANGP00000011255 [Apis
                                                                                                                                                                  3E-033 DROSOPHILA PSEUDOOBSCURA M
                                                                                                                                   GA11196-PA [Drosophila pseudoobscura]         142 3e-033
                                                                                                                                                                  4E-017 SIMILAR TO MELLIFERA CG9328-P
                                                                                                                                   similar to ENSANGP00000022512 [Apis
                                                                                                                                                                  5E-027      121 5e-027
                                                                                                                                   MGC68812 protein [Xenopus laevis] XENOPUS LAEVIS BRK1-LIKE HOM
                                                                                                                                                                  3E-011
                                                                                                                                   unknown salivary protein [Culicoides UNKNOWN SALIVARY CULICOIDES
                                                                                                                                                                  7E-004 DROSOPHILA PSEUDOOBSCURA I
                                                                                                                                   GA17338-PA [Drosophila pseudoobscura]          45 7e-004
                                                                                                                                                                  3E-030 PREDICTED SIMILAR TO FUN14 DO
                                                                                                                                   PREDICTED: similar to FUN14 domain
                                                                                                                                                                  5E-053 SIMILAR TO MELLIFERA ANOPHEL
                                                                                                                                   similar to CG11137-PA [Apis mellifera] 208 5e-053
                                                                                                                                                                  8E-021 HYPOTHETICAL
                                                                                                                                   hypothetical protein [Pongo pygmaeus] 100 8e-021 PONGO PYGMAEU
                                                                                                                                                                  1E-030
                                                                                                                                   similar to UPF0197 protein C11orf10 SIMILAR TO HOMOLOG MUS MUSC
                                                                                                                                                                  1E-016 CG7781-PA DROSOPHILA MELANO
                                                                                                                                   CG7781-PA [Drosophila melanogaster]
                                                                                                                                                                  6E-018
                                                                                                                                   unnamed protein product [Tetraodon nUNNAMED PRODUCT TETRAODON
                                                                                                                                   P11F3 [Xenopus laevis]                  XENOPUS
                                                                                                                                                                  2E-010 67 2e-010 LAEVIS RIKEN CDNA MU
                                                                                                                                                                  2E-007
                                                                                                                                   PREDICTED: similar to hepatitis B v PREDICTED SIMILAR TO HEPATITI
                                                                                                                                                                  6E-037 SALIVARY 1 IXODES SCAPULARIS
                                                                                                                                   fed tick salivary protein 1 [Ixodes s
                                                                                                                                                                  7E-046    183 7e-046
                                                                                                                                   hypothetical protein [Ixodes pacificus] HYPOTHETICAL IXODES PACIFICU
                                                                                                                                                                  3E-080 SALIVARY 6 IXODES SCAPULARIS
                                                                                                                                   fed tick salivary protein 6 [Ixodes s

                                                                                                                                                                  1E-108
                                                                                                                                   fed tick salivary protein 7 [Ixodes s   SALIVARY 7 IXODES SCAPULARIS

                                                                                                                                                                 7E-087
                                                                                                                                   unnamed protein product [Tetraodon nUNNAMED PRODUCT TETRAODON
                                                                                                                                                                 7E-067
                                                                                                                                   elongation factor 1-beta [Artemia salinELONGATION FACTOR 1-BETA AR
                     PCGP -> PCGPppE 74                                                                                                                          1E-039 SIMILAR TO PROBABLE SPLICING
                                                                                                                                   similar to Probable splicing factor
                                                                                         WC                                                                      5E-080 ANOPHELES GAMBIAE STR. PEST
                                                                                                                                   ENSANGP00000011120 [Anopheles gambiae
                                                                                                                                                                 8E-054 DROSOPHILA PSEUDOOBSCURA C
                                                                                                                                   GA16529-PA [Drosophila pseudoobscura]       210 8e-054

                                                                                                                                                           6E-066 SIMILAR TO MELLIFERA TBN-PROV
                                                                                                                                   similar to ENSANGP00000016698 [Apis

                                                                                                                                                                4E-095
                                                                                                                                   tetraspanin-like protein [Dermacentor TETRASPANIN-LIKE DERMACENTO

                                                                                                                                                               2E-017     90 2e-017
                                                                                                                                   cystatin [Lepidoglyphus destructor] CYSTATIN LEPIDOGLYPHUS DEST
                                                                                                                                                               2E-021
                                                                                                                                   similar to Death-associated protein SIMILAR TO DEATH-ASSOCIATED
                                                                                                                                                                  scapula
                                                                                                                                   alpha-2-macroglobulin [Ixodes 0.0     ALPHA-2-MACROGLOBULIN IXODE

                                                                                                                                                               9E-059 RIBOSOMAL L30
                                                                                                                                   ribosomal protein L30 [Ixodes pacificus] 226 9e-059 IXODES PACIFICU
                                                                                                                                                               1E-073 RIBOSOMAL 13
                                                                                                                                   ribosomal protein 13 [Lonomia obliqua] 277 1e-073 LONOMIA OBLIQUA
                                                                                                                                                               4E-059
                                                                                                                                   ribosomal protein S10 [Spodoptera fruRIBOSOMAL S10 SPODOPTERA FR
                                                                                                                                                               5E-027 XENOPUS TROPICALIS LAEVIS RIB
                                                                                                                                   MGC89823 protein [Xenopus tropicalis]
                                   9E-039 CG5827-PB ISOFORM B DROSOPH
     CG5827-PB, isoform B [Drosophila me
                                   5E-085 RIBOSOMAL L12
     ribosomal protein L12 [Ixodes pacificus] 314 5e-085 IXODES PACIFICU
                                   8E-051      200 8e-051
     MGC82136 protein [Xenopus laevis] XENOPUS LAEVIS TROPICALIS RIB
                                   rerio]
     ribosomal protein S8 [Danio 8E-093 RIBOSOMAL S8 DANIO RERIO RS8
                                   4E-055
     ribosomal protein, large P2 [Ixodes p RIBOSOMAL LARGE P2 IXODES PA
                                   1E-149 RIBOSOMAL L7A IXODES PACIFICU
     60S ribosomal protein L7A [Ixodes pac
                                            379 e-104
     QM protein [Pinctada fucata]1E-104 PINCTADA FUCATA PLUTELLA XYL
                                   1E-136 CERATITIS CAPITATA RLA0_CERC
     P0 protein [Ceratitis capitata] >gnl|
                                   1E-124
     ribosomal protein S4 [Spodoptera frugRIBOSOMAL S4 SPODOPTERA FRU
                                   1E-033      143 1e-033
     ribosomal protein L32 [Bombyx mori] RIBOSOMAL L32 BOMBYX MORI SP
                                   7E-044
     ribosomal protein L22 [BranchiostomaRIBOSOMAL L22 BRANCHIOSTOMA
                                   2E-026 HYPOTHETICAL GALLUS UNKNOW
     hypothetical protein [Gallus gallus]   119 2e-026
                                   4E-078      291 4e-078
     ribosomal protein L17 [Bombyx mori] RIBOSOMAL L17 BOMBYX MORI 31
                                   6E-026
     ribosomal protein S29 [BranchiostomaRIBOSOMAL S29 BRANCHIOSTOM
                                   6E-096      351 6e-096
     ribosomal protein L15 [Bombyx mori] RIBOSOMAL L15 BOMBYX MORI RP
                                   5E-063 SIMILAR TO DROSOPHILA MELANO
     similar to Drosophila melanogaster CG
                                   1E-046
     ribosomal protein L26 [Argopecten irr RIBOSOMAL L26 ARGOPECTEN IR
                                   7E-098 SIMILAR TO RIBOSOMAL L7 APIS M
     similar to ribosomal protein L7 [Ap
                                   2E-052 SIMILAR TO RIBOSOMAL S19 APIS
     similar to ribosomal protein S19 [A
                                   1E-086
     ribosomal protein L19 [Crassostrea g RIBOSOMAL L19 CRASSOSTREA G
                                   1E-113       410 e-113
     Parcxpwex01 [Periplaneta americana] PARCXPWEX01 PERIPLANETA AM
                                   6E-086 RIBOSOMAL L11 DANIO RERIO XE
     ribosomal protein L11 [Danio rer
                                   7E-082 RIBOSOMAL S15
     ribosomal protein S15 [Ixodes pacificus] 303 7e-082 IXODES PACIFICU
                                   2E-054
     60S ribosomal protein L37 [Ixodes pacRIBOSOMAL L37 IXODES PACIFICU
                                   2E-055
     ribosomal protein S17 [BranchiostomaRIBOSOMAL S17 BRANCHIOSTOM
                                   6E-082 RIBOSOMAL L21 ORNITHODOROS
     ribosomal protein L21 [Ornithodoros m
                                   3E-039
     40S ribosomal protein S27 [LumbricusRIBOSOMAL S27 LUMBRICUS RUB
                                   5E-041
     ribosomal protein L34 [BranchiostomaRIBOSOMAL L34 BRANCHIOSTOMA
                                   9E-042 SIMILAR TO RIBOSOMAL L35A API
     similar to ribosomal protein L35A [
WP                                 2E-072 RIBOSOMAL L23 BOMBYX MORI SP
     ribosomal protein L23 [Bombyx mori] >
                                   3E-050 SIMILAR TO RIBOSOMAL L31 APIS
     similar to ribosomal protein L31 [A
                                   4E-079 RIBOSOMAL S11 DERMACENTOR
     40S ribosomal protein S11 [Dermacento
                                   2E-041 RPL36 MUSCULUS PREDICTED SIM
     Rpl36 protein [Mus musculus] >gnl|BL_
                                   1E-070
     unnamed protein product [Tetraodon nUNNAMED PRODUCT TETRAODON
                                   1E-080 RIBOSOMAL S14
     ribosomal protein S14 [Ixodes pacificus] 299 1e-080 IXODES PACIFICU
                                   1E-047
     ribosomal protein L26 [Argopecten irr RIBOSOMAL L26 ARGOPECTEN IR
                                   3E-061
     60S ribosomal protein L35-like protei RIBOSOMAL L35-LIKE IXODES PAC
                                   1E-036      152 1e-036
     MGC83076 protein [Xenopus laevis] XENOPUS LAEVIS RIBOSOMAL L14
                                   1E-101       369 e-101
     ribosomal protein L10A [Bombyx mori]RIBOSOMAL L10A BOMBYX MORI S
                                   2E-079 SIMILAR TO RIBOSOMAL L18 APIS
     similar to ribosomal protein L18 [A
                                   2E-071
     ribosomal protein S7 [Argopecten irra RIBOSOMAL S7 ARGOPECTEN IRR
                                   2E-022 ANOPHELES GAMBIAE STR. PEST
     ENSANGP00000020220 [Anopheles gambiae
                                   3E-048 SIMILAR TO MELLIFERA TRANSLA
     similar to ENSANGP00000014056 [Apis
                                   1E-115
     40S ribosomal protein S5 [Ixodes paciRIBOSOMAL S5 IXODES PACIFICU
                                   3E-046
     hypothetical protein MGC63631 [Dani HYPOTHETICAL DANIO RERIO PRE
                                   4E-066
     Ribosomal protein L27A2 [Plutella xy RIBOSOMAL PLUTELLA XYLOSTEL
                                   6E-043 ANOPHELES GAMBIAE STR. PEST
     ENSANGP00000017618 [Anopheles gambiae
                                   5E-058 RIBOSOMAL L44
     ribosomal protein L44 [Ixodes pacificus] 224 5e-058 IXODES PACIFICU
                                   1E-081     303 1e-081
     ribosomal protein S18 [Ixodes ricinus] RIBOSOMAL S18 IXODES RICINUS
                                   7E-047
     Unknown (protein for MGC:77927) [DaUNKNOWN FOR MGC DANIO RERI
                                   1E-068 RIBOSOMAL S16 HETEROPNEUST
     ribosomal protein S16 [Heteropneustes
                                   1E-069
     PREDICTED: similar to ribosomal pro PREDICTED SIMILAR TO RIBOSOM
                                   3E-068 RIBOSOMAL S12 DERMACENTOR
     40S ribosomal protein S12 [Dermacento
                                   9E-029
     PREDICTED: similar to ribosomal pro PREDICTED SIMILAR TO RIBOSOM
                                   2E-047
     40S ribosomal protein S24 [Ictalurus RIBOSOMAL S24 ICTALURUS PUNC
                                   3E-029 ANOPHELES GAMBIAE STR. PEST
     ENSANGP00000021509 [Anopheles gambiae
                                   1E-147
     guanine nucleotide-binding protein [P GUANINE NUCLEOTIDE-BINDING P
                                   3E-052 SIMILAR TO RIBOSOMAL S19 APIS
     similar to ribosomal protein S19 [A
                                   3E-052 SIMILAR TO RIBOSOMAL S19 APIS
     similar to ribosomal protein S19 [A
                                   2E-022 SAPIENS CHROMOSOME 13 OPEN
     OTTHUMP00000040977 [Homo sapiens] >g
                                   6E-091
     S9e ribosomal protein [Meladema coriRIBOSOMAL MELADEMA CORIACE
                                   4E-066 RIBOSOMAL S30 IXODES PACIFICU
     40S ribosomal protein S30 [Ixodes pac
                                   1E-006 RIBOSOMAL L41
     ribosomal protein L41 [Ixodes pacificus] 54 1e-006 IXODES PACIFICU
                          2E-075 UNNAMED PRODUCT MUS MUSCU
unnamed protein product [Mus musculus] 284 2e-075
                          2E-022 DROSOPHILA MELANOGASTER PU
CG14283-PA [Drosophila melanogaster

                             8E-085 PARTNER NOB1 ORYZIAS LATIPES
partner of Nob1 [Oryzias latipes]     315 8e-085
                             2E-073 DANIO RERIO UBIQUITIN-CONJUG
zgc:86727 [Danio rerio] >gnl|BL_
                             3E-083
ubiquitin/ribosomal protein S27a fusi UBIQUITIN RIBOSOMAL S27A FUSI
                             2E-043
similar to Drosophila melanogaster RpSIMILAR TO DROSOPHILA MELANO

                               4E-047 HYPOTHETICAL TRICHODESMIUM
hypothetical protein Tery02001221
                               1E-041 HYPOTHETICAL TRICHODESMIUM
hypothetical protein Tery02001221
                               3E-017 HYPOTHETICAL CAENORHABDITIS
Hypothetical protein F35G2.4 [Caenorh
                               2E-085 ANOPHELES GAMBIAE STR. PEST
ENSANGP00000027211 [Anopheles gambiae
                               3E-029 ANOPHELES GAMBIAE STR. PEST
ENSANGP00000018738 [Anopheles gambiae
                               3E-061
PREDICTED: similar to procollagen-p PREDICTED SIMILAR TO PROCOLL
                               2E-024
PREDICTED: similar to Microsomal si PREDICTED SIMILAR TO MICROSO
                               2E-038
Vitamin K epoxide reductase complex,VITAMIN K EPOXIDE REDUCTASE
cyclophilin A [Chlamys farreri]           CYCLOPHILIN A CHLAMYS FARRE
                               3E-076 285 3e-076
                               4E-031 IMMUNOPHILIN VICIA FABA ARABI
immunophilin [Vicia faba] >gnl|BL_ORD_
                               9E-042 DEFENDER AGAINST PROGRAMM
defender against programmed cell deat
                               5E-053
putative heat shock-related protein [ PUTATIVE HEAT SHOCK-RELATED
                               7E-078 SIMILAR TO SMALL GLUTAMINE-R
similar to small glutamine-rich tet
                               8E-054 ANOPHELES GAMBIAE STR. PEST
ENSANGP00000021015 [Anopheles gambiae
                               tropicalis
Txn2-prov protein [Xenopus 2E-029 TXN2-PROV XENOPUS TROPICALI
                                  0.0
putative secreted salivary gland pept PUTATIVE SECRETED SALIVARY G
                               4E-094 SALIVARY 5 IXODES SCAPULARIS
fed tick salivary protein 5 [Ixodes s
                               1E-055 SALIVARY 3 IXODES SCAPULARIS
fed tick salivary protein 3 [Ixodes s
                                  0.0
putative serine protease with signal PUTATIVE SERINE PROTEASE WIT

                             1E-051
signal sequence receptor beta-like p SIGNAL SEQUENCE RECEPTOR B
                             3E-014      79 3e-014
MGC83844 protein [Xenopus laevis] XENOPUS LAEVIS DERIVED NEUR
                             2E-014      80 2e-014
MGC83844 protein [Xenopus laevis] XENOPUS LAEVIS HYPOTHETICAL
                             4E-023     108 4e-023
MGC84493 protein [Xenopus laevis] XENOPUS LAEVIS UNNAMED PRO
                             8E-013 HYPOTHETICAL GALLUS SIMILAR
hypothetical protein [Gallus gallus]
                             2E-073 CG6359-PA ISOFORM A DROSOPH
CG6359-PA, isoform A [Drosophila me
                             3E-067 ANOPHELES GAMBIAE STR. PEST
ENSANGP00000018480 [Anopheles gambiae
                             1E-041     170 1e-041
LOC398633 protein [Xenopus laevis] XENOPUS LAEVIS DANIO RERIO T
                             2E-097
ADP-ribosylation factor 1 [Mus musculADP-RIBOSYLATION FACTOR 1 MU

                            2E-065 CU-ZN SUPEROXIDE DISMUTASE 1
Cu-Zn superoxide dismutase 1 [Lasius
                            6E-040 TETRATRICOPEPTIDE REPEAT DO
tetratricopeptide repeat domain 11

                               7E-004 HYPOTHETICAL CAENORHABDITIS
Hypothetical protein CBG22046 [Caeno
                               7E-023 DROSOPHILA YAKUBA CG6770-PA
CG6770 [Drosophila yakuba] >gnl|BL_OR
                               1E-052
PREDICTED: similar to germinal hist PREDICTED SIMILAR TO GERMINA
                                mellif
similar to Histone H2B [Apis 5E-056 SIMILAR TO HISTONE H2B APIS ME
                               1E-054
similar to chromobox homolog 3; het SIMILAR TO CHROMOBOX HOMOL
                               1E-128 SALIVARY 8 IXODES SCAPULARIS
fed tick salivary protein 8 [Ixodes s

                         4E-063      242 4e-063
MGC80885 protein [Xenopus laevis] XENOPUS LAEVIS DANIO RERIO H
                         2E-052 CG2210-PA DROSOPHILA MELANO
CG2210-PA [Drosophila melanogaster]

                             6E-040 TETRATRICOPEPTIDE REPEAT DO
tetratricopeptide repeat domain 11
                             2E-052
putative salivary secreted peptide [I PUTATIVE SALIVARY SECRETED P
                             1E-116 CG3283-PA DROSOPHILA MELANO
CG3283-PA [Drosophila melanogaster]
                             9E-064 ANOPHELES GAMBIAE STR. PEST
ENSANGP00000016107 [Anopheles gambiae
                             1E-134
cytochrome oxidase 3 [Ixodes persulc CYTOCHROME OXIDASE 3 IXODES
                             1E-150 ru
ADP-ATP translocator [Ethmostigmus ADP-ATP TRANSLOCATOR ETHMO
                             1E-019 ISOFORM B DROSOPHILA MELANO
CG32230-PB, isoform B [Drosophila m
                             3E-037
similar to Drosophila melanogaster ATSIMILAR TO DROSOPHILA MELANO
                             7E-006
ubiquinol-cytochrome c reductase (6 UBIQUINOL-CYTOCHROME C RED
                             2E-059 DEHYDROGENASE 6 IXODES PER
NADH dehydrogenase 6 [Ixodes persulc
                               2E-076
ATP synthase c-subunit [Ixodes pacifi SYNTHASE C-SUBUNIT IXODES PA
                               1E-107
ATPase subunit 6 [Ixodes persulcatus ATPASE SUBUNIT 6 IXODES PERS
                               1E-102
cytochrome oxidase 2 [Ixodes persulc CYTOCHROME OXIDASE 2 IXODES
cytochrome oxidase subunit 1 0.0 [Ixodes CYTOCHROME OXIDASE SUBUNIT
                               2E-032 BASIC AMBLYOMMA HEBRAEUM M
9.8 kDa basic protein [Amblyomma hebr
cytochrome c [Ixodes pacificus]           228 3e-059
                               3E-059 CYTOCHROME C IXODES PACIFIC
                               6E-004 ANOPHELES GAMBIAE STR. PEST
ENSANGP00000010662 [Anopheles gambiae
                               1E-071 ANOPHELES GAMBIAE STR. PEST
ENSANGP00000012069 [Anopheles gambiae
                               7E-039 SIMILAR TO DROSOPHILA MELANO
similar to Drosophila melanogaster CG
                               3E-038 SYNTHASE 1 LONOMIA OBLIQUA U
ATP synthase 1 [Lonomia obliqua]            159 3e-038
                               3E-024 PREDICTED SIMILAR TO NADH DE
PREDICTED: similar to NADH dehydrog
                               4E-025 CG7580-PA DROSOPHILA MELANO
CG7580-PA [Drosophila melanogaster]
cytochrome c oxidase subunit IV             192 3e-048
                               3E-048 CYTOCHROME C OXIDASE SUBUN
                               7E-027 DROSOPHILA PSEUDOOBSCURA S
GA10165-PA [Drosophila pseudoobscura]          121 7e-027
GekBS043P [Gekko japonicus]                 60 1e-008
                               1E-008 GEKBS043P GEKKO JAPONICUS C
                               4E-011 CYTOCHROME C OXIDASE SUBUN
cytochrome c oxidase subunit VIc prec
                               3E-039 ANOPHELES GAMBIAE STR. PEST
ENSANGP00000011122 [Anopheles gambiae
                               2E-040 BETA-KETOACYL- ACYL-CARRIER
FabG (beta-ketoacyl-[acyl-carrie
                               2E-062 ru
ADP-ATP translocator [Ethmostigmus ADP-ATP TRANSLOCATOR ETHMO
                               8E-066
mitochondrial malate dehydrogenase MITOCHONDRIAL MALATE DEHYD
                               7E-026 SIMILAR TO DROSOPHILA MELANO
similar to Drosophila melanogaster CG
                               1E-180 SALIVARY 9 IXODES SCAPULARIS
fed tick salivary protein 9 [Ixodes s
                                 0.0
putative secreted NADH-ubiquinone oxi    PUTATIVE SECRETED NADH-UBIQ
                               4E-016
macrophage migration inhibitory facto MACROPHAGE MIGRATION INHIBI
                                 0.0
putative secreted salivary gland pept PUTATIVE SECRETED SALIVARY G

                            2E-023
peptidoglycan recognition protein [Ar PEPTIDOGLYCAN RECOGNITION A

                             5E-071    267 5e-071
hypothetical protein [Ixodes ricinus] HYPOTHETICAL IXODES RICINUS
                                0.0
salivary gland protein [Ixodes scapul SALIVARY GLAND IXODES SCAPU
                             9E-062
putative secreted salivary gland pept PUTATIVE SECRETED SALIVARY G

                           5E-063 CG3201-PA DROSOPHILA MELANO
CG3201-PA [Drosophila melanogaster]
                           1E-069 IGE-DEPENDENT HISTAMINE RELE
IgE-dependent histamine release facto
                            Best                     Best                                                                        Best
                          match to                 match to                                                                    match to
Comment                      GO                      KOG                      General        Best match to                      SMART
   s           Class      database      E value    database      E value       class        PFAM database          E value     database      E value


            te                     3E-20 Predicted transposase Replication, recombination and repair
Predicted transposase cellular_component unknown       9E-020

             h/uc         protein axoneme - protein binding biogenesis protein eyeDaxx and modification, Translation, ribosomal structure and biogenesis
                                           3E-11 Ribosome - visual
                                                               5E-006 RNA processing   photoreceptor cell development
Very charged secreted cilium - - Psiblast clusters with calreticulinsperception -- Nop56p/Sik1p              3E-005
             h/uc                          0.041
unknown conserved biological_process unknown - molecular_function unknown - cellular_component unknown
             h/uc
Uncharacterized conserved protein                                                     DUF786                 2E-029
             h/uc                        0.000002 Endocytic adaptor protein intersectin
                                                                0.070 Signal transduction
                                                                                      DUF1151                3E-008
unknown conserved molecular_function unknown - regulation of cell growth - nucleus mechanisms, Intracellular trafficking, secretion, and vesicular trans
             h/uc                          0.098
unknown conserved cellular_component unknown
             h/uc
unknown conserved
             h/uc                         0.0004
FN5 conserved protein molecular_function unknown - biological_process unknown - cellular_component unknown
             h/uc
Predicted membrane protein                 4E-12 Predicted membrane protein
                                                               3E-011 Function unknown
                          embryonic development (sensu Animalia)                      FUN14                  2E-017
             h/uc
Predicted membrane protein                 6E-19 Predicted membrane protein
                                                               2E-045 Function unknownDUF1077
                          biological_process unknown - molecular_function unknown - endoplasmic reticulum    4E-045
             h/uc
unknown conserved
             h/uc         integral         1E-31               5E-022 Function unknown
Predicted membrane protein to membrane Predicted membrane protein                     UPF0197                5E-022
conserved h/uc
             h/uc                                               protein, Inorganic ion transport
Ca2+ binding protein, contains EF-hand motifsCa2+ binding 7E-014 contains EF-hand motifsand metabolism
             h/uc
unknown conserved peptide
             h/uc         viral life cycle - protein
                                           2E-07
similar to hepatitis B virus x-interacting response to virus
             h/uc                          5E-25 Uncharacterized conserved protein
unknown conserved positive regulation of growth rate           8E-012 Function unknown
              protein conserved in Ixodes pacificus
hypotheticalh/uc
             h/uc                         0.0006
unknown conserved biological_process unknown - cellular_component unknown

         h/tr         mitochondrion6E-10
Rhodanese-related sulfurtransferase                Rhodanese-related sulfurtransferase transport and metabolism
                                                              9E-017 Inorganic ion   Rhodanese             3E-010             RHOD           8E-013

            initiation factor 3, subunit 2E-83factor activity - initiation factor 3, subunit finitiation structure andtranslation initiation factor 3 complex
Translation h/tm                          f (eIF-3f) Translation regulation of translational (eIF-3f) - eukaryotic5E-015 JAB_MPN 4E-020
                          translation initiation                     3E-099 Translation,Mov34 ribosomal                biogenesis
            h/tm          cytosol                                    9E-063 Transcription
Elongation factor 1 beta/delta chain 3E-67 Elongation factor 1 beta/delta chain F1_GNE       E                       4E-029
            h/tm          molecular_function unknown - biological_process unknown - cellular_component unknown
Pre-mRNA splicing factor SF3b                                        1E-033 Function unknown
                                          3E-29 Uncharacterized conserved proteinSF3b10                              5E-037
            h/tm          protein binding - SCF SCF ubiquitin ligase, Posttranslational
                                                                      complex                Skp1                    1E-031 Skp1
RNA polymerase II elongation factor 9E-79 ubiquitin ligase6E-054 Skp1 component modification, protein turnover, chaperones                      9E-033
            initiation factor 5A (eIF-5A)
Translation h/tm                          1E-54 Translation cytosol - salivary gland eIF-5a
                                                                     5E-054 Translation, cell ribosomal autophagic 9E-014
                                                                                                                      cell death
                          translation initiation factor activity - initiation factor 5A (eIF-5A) death -structure and biogenesis

          h/tf        cell growth and/or maintenance
                                     3E-55 TBP-associated transcription factor Prodos
                                                           7E-049 has signal peptide
TBP-associated transcription factor Prodos - Drosophila homolog alsoTranscription                                             BTP            4E-014

            family     lysosomal membrane integral to plasma integral membrane protein
                                    2E-33                  4E-033 General function prediction membrane
                                                                               Tetraspannin
Tetraspaninh/tetra integral membrane protein- Tetraspanin family membrane - lysosome - plasma only 8E-031

cystatin                 cysteine protease inhibitor activity - endopeptidase inhibitor activity
            h/prot inhibitor            4E-11                                         Cystatin               0.013 CY                4E-004
            h/st         induction of apoptosis
similar to Death-associated protein 1 5E-20 by extracellular signals
            h/st                        activity enzyme binding - protein homooligomerization activity - intracellular protein transport - extracellular - endopept
                                                                 1E-057               A2M                   3E-049 SRA
Alpha-macroglobulin protein carrier 1E-48 - Alpha-macroglobulin Posttranslational modification, protein turnover, chaperones0.045

           h/ps/rp     peripheral nervous system development
60S ribosomal protein L30                                       5E-045 Translation,Ribosomal_L7Ae
                                        1E-47 60S ribosomal protein L30                                   7E-020
                                                                                    ribosomal structure and biogenesis
           h/ps/rp     RNA binding -9E-72 60S ribosomal protein L9 - protein biosynthesis - ribosome 1E-007
60S ribosomal protein L9                                        2E-045 Translation,Ribosomal_L6
                                         structural constituent of ribosome         ribosomal structure and biogenesis
           h/ps/rp     RNA               structural constituent of ribosome -
                                                                1E-049 Translation,S10_plectin
                                                                                    ribosomal structure and biogenesis
                                                                                                          4E-046
40s ribosomal protein s10 binding -7E-57 40s ribosomal protein s10 protein biosynthesis - cytosolic small ribosomal subunit (sensu Eukarya)
           h/ps/rp     intracellular - ribosome 60S ribosomal protein L38 subunit (sensu Eukarya) - structural constituent of ribosome - RNA binding - protein
60S ribosomal protein L38                                       1E-017 Translation,Ribosomal_L38e
                                        4E-27 - cytosolic large ribosomal                                 1E-016
                                                                                    ribosomal structure and biogenesis
             h/ps/rp
60S ribosomal protein L37                   9E-37 60S ribosomal protein L37
                                                                    4E-028 Translation,Ribosomal_L37ae and development (sensu Nematoda) - growth
                                                                                            ribosomal structure     3E-025
                           embryonic development (sensu Animalia) - positive regulation of growth rate - larvalbiogenesis
             h/ps/rp       RNA               structural constituent of ribosome
                                                                    2E-073 Translation,Ribosomal_L11 subunit (sensu Eukarya)
                                                                                            large ribosomal
40S ribosomal protein S2 binding -6E-73 40S ribosomal protein S2- cytosolic ribosomal structure and biogenesis      3E-014 RL11           2E-033
             h/ps/rp
40S ribosomal protein S20                   2E-51 - cytosolic small ribosomal
                                                                    3E-040 Translation, (sensu Eukarya)
                                                                                            ribosomal structure and biogenesis
                                                                                                                    1E-025
                           intracellular - ribosome 40S ribosomal protein S20 subunit Ribosomal_S10 - structural constituent of ribosome - RNA binding - protein
             h/ps/rp
40S ribosomal protein S8                    2E-76 40S ribosomal - growthTranslation,Ribosomal_S8e
                                                                    1E-077      -           ribosomal structure and biogenesis
                           larval development (sensu Nematoda) protein S8 physiological process - reproduction      2E-036
             h/ps/rp       RNA P2            structural constituent of ribosome - protein Ribosomal_60s
                                                                    9E-025 Translation, ribosomal structure and biogenesis
                                                                                                                    3E-004
60S acidic ribosomal protein binding -3E-37 60S acidic ribosomal protein P2 biosynthesis - cytosolic large ribosomal subunit (sensu Eukarya)
             h/ps/rp
60S ribosomal protein L7A                    genital 60S ribosomal - physiological process - reproduction and biogenesis
                                                                    6E-060 Translation,Ribosomal_L7Ae
                           hermaphrodite2E-87 morphogenesis protein L7A                     ribosomal structure     3E-015
             h/ps/rp
60s ribosomal protein L10                      0      60s ribosomal protein L10
                                                                    6E-081 Translation,Ribosomal_L10e
                           cytosolic large ribosomal subunit (sensu Eukarya)                                        1E-081
                                                                                            ribosomal structure and biogenesis
             h/ps/rp       structural          0       ribosome DNA-(apurinic or apyrimidinic site)structure and - cytosolic
                                                                    1E-107 Translation, ribosomal lyase             1E-025
60S acidic ribosomal protein P0 constituent of60S acidic -ribosomal protein P0 Ribosomal_L10 activity biogenesis ribosome (sensu Eukarya) - protein bio
             h/ps/rp       RNA                 0
40S ribosomal protein S4 binding - structural constituent of protein S4- protein biosynthesis - cytosolic small ribosomal subunit2E-005 Eukarya)
                                                      40S ribosomal ribosome
                                                                    1E-117 Translation,Ribosomal_S4e                1E-023 S4
                                                                                            ribosomal structure and biogenesis             (sensu
             h/ps/rp
60S ribosomal protein L32                   2E-15                                          Ribosomal_L32e           1E-019
                           protein biosynthesis - cytosolic large ribosomal subunit (sensu Eukarya) - structural constituent of ribosome
             h/ps/rp       RNA               structural constituent of ribosome -
                                                                    1E-034 Translation,Ribosomal_L22e
                                                                                            ribosomal structure and biogenesis
                                                                                                                    5E-036
60S ribosomal protein L22 binding -8E-44 60S ribosomal protein L22 protein biosynthesis - cytosolic large ribosomal subunit (sensu Eukarya)
             h/ps/rp       RNA               structural constituent of ribosome -
                                                                    7E-017 Translation,Ribosomal_L28e
                                                                                            ribosomal structure and biogenesis
                                                                                                                    1E-017
60S ribosomal protein L28 binding -5E-26 60S ribosomal protein L28 protein biosynthesis - cytosolic large ribosomal subunit (sensu Eukarya)
             h/ps/rp       RNA               structural constituent of ribosome -
                                                                    2E-060 Translation,Ribosomal_L22
60S ribosomal protein L22 binding -5E-75 60S ribosomal protein L22 ribosomeribosomal structure and biogenesis       2E-023
             h/ps/rp
40S ribosomal protein S29                   2E-24 40S ribosomal protein S29
                                                                    8E-020 Translation, ribosomal structure and biogenesis
                           positive regulation of body size - embryonic development (sensu Animalia) - positive regulation of growth rate - larval development (se
             h/ps/rp
60s ribosomal protein L15                   5E-85 60s ribosomal protein L15
                                                                    3E-085 Translation,Ribosomal_L15e
                                                                                            ribosomal structure and biogenesis
                           positive regulation of growth rate - physiological process - reproduction - gametogenesis6E-067
             h/ps/rp       embryonic        1E-56 40S ribosomal protein S15/S22
                                                                    2E-062 Translation,Ribosomal_S8
                                                                                            ribosomal structure and development (sensu Nematoda) - growth - physio
40S ribosomal protein S15/S22 development (sensu Animalia) - positive regulation of growth rate - larvalbiogenesis  2E-035
             h/ps/rp
60S ribosomal protein L26                   7E-43 - cytosolic large ribosomal
                                                                    3E-031 Translation,KOW  ribosomal structure and0.015 KOW
                                                                                                                      biogenesis
                           intracellular - ribosome 60S ribosomal protein L26 subunit (sensu Eukarya) - RNA binding - protein biosynthesis  0.044
             h/ps/rp
60S ribosomal protein L7                     structural constituent of ribosome
                                                                    3E-072 Translation,Ribosomal_L30
                                                                                            ribosomal structure and biogenesis
                                                                                                                    7E-013
                           RNA binding -5E-90 60S ribosomal protein L7 - protein biosynthesis - cytosolic large ribosomal subunit (sensu Eukarya)
             h/ps/rp
40S ribosomal protein S19                   5E-51 - protein biosynthesis Translation,Ribosomal_S19e
                                                                    3E-054
                           intracellular - ribosome 40S ribosomal protein S19                                       6E-056 HTH_DTXR 5E-004
                                                                                            ribosomal structure and biogenesis
             h/ps/rp
60s ribosomal protein L19                   5E-73 60s ribosomal protein L19
                                                                    1E-052 Translation,Ribosomal_L19e
                                                                                            ribosomal structure and biogenesis
                                                                                                                    4E-043
                           embryonic development (sensu Animalia) - embryonic morphogenesis - larval development (sensu Nematoda) - growth - reproduction
             h/ps/rp
40S ribosomal protein S3A                   2E-88 40S ribosomal protein S3A
                                                                    2E-090 Translation,Ribosomal_S3Ae
                                                                                            ribosomal Nematoda)2E-084 - hermaphrodite genital morphogenesis - p
                           embryonic development (sensu Animalia) - larval development (sensustructure and- biogenesisgrowth
             h/ps/rp
60S ribosomal protein L11                   2E-85 - cytosolic large ribosomal
                                                                    4E-087 Translation,Ribosomal_L5_C and biogenesis
                                                                                            ribosomal structure     3E-036
                           intracellular - ribosome 60S ribosomal protein L11 subunit (sensu Eukarya) - structural constituent of ribosome - RNA binding - rRNA b
             h/ps/rp
40S ribosomal protein S15                   6E-58 40S ribosomal protein S15
                                                                    3E-068 Translation,Ribosomal_S19
                                                                                            ribosomal structure and development (sensu Nematoda) - growth - physio
                                                                                                                    4E-027
                           embryonic development (sensu Animalia) - positive regulation of growth rate - larvalbiogenesis
             h/ps/rp
60S ribosomal protein L37                   2E-35 - cytosolic large ribosomal
                                                                    5E-024 Translation,Ribosomal_L37e
                                                                                            ribosomal structure and biogenesis
                                                                                                                    binding
                           intracellular - ribosome 60S ribosomal protein L37 subunit (sensu Eukarya) - RNA 2E-011 - protein biosynthesis
             h/ps/rp       RNA               structural constituent of ribosome -
                                                                    1E-053 Translation,Ribosomal_S17e
                                                                                            ribosomal structure and biogenesis
                                                                                                                    4E-046
40S ribosomal protein S17 binding -9E-52 40S ribosomal protein S17 protein biosynthesis - cytosolic small ribosomal subunit (sensu Eukarya)
             h/ps/rp       RNA               structural constituent of ribosome -
                                                                    5E-051 Translation,Ribosomal_L21e
                                                                                            ribosomal structure and biogenesis
                                                                                                                    4E-032
60S ribosomal protein L21 binding -5E-58 60S ribosomal protein L21 protein biosynthesis - cytosolic large ribosomal subunit (sensu Eukarya)
             h/ps/rp       RNA               structural constituent of ribosome -
                                                                    2E-031 Translation,binding - protein
                                                                                            ribosomal structure and biogenesis
                                                                                                                    4E-018
40s ribosomal protein S27 binding -1E-39 40s ribosomal protein S27 zinc ion Ribosomal_S27ebiosynthesis - signal transduction - cell proliferation - cytos
             h/ps/rp
60s ribosomal protein L34                   1E-32 60s ribosomalribosomalTranslation,Ribosomal_L34e
                                                                      protein subunit (sensu Eukarya) - structural biogenesis of ribosome
                           protein biosynthesis - cytosolic large 2E-029 L34                                        4E-024
                                                                                            ribosomal structure and constituent
             h/ps/rp       tRNA binding 4E-39 60S ribosomal protein L35A/L37 Ribosomal_L35Ae and biogenesis
60S ribosomal protein L35A/L37                                      3E-032 Translation, ribosomal structure         2E-027
             h/ps/rp       embryonic development (sensu Animalia) - larval development (sensustructure and- biogenesis
                                                                    2E-048 Translation, ribosomal Nematoda)3E-030 -PAC
60S ribosomal protein L14/L17/L23 3E-66 60S ribosomal protein L14/L17/L23Ribosomal_L14                                                      process
                                                                                                                      growth physiological 0.085 - reproduction
             h/ps/rp
60S ribosomal protein L31                   6E-50      ribosome - cytosolic large
                                                                    1E-036 Translation,Ribosomal_L31e
                                                                                            ribosomal structure and biogenesis
                                                                                                                    3E-029
                           structural constituent of60S ribosomal protein L31 ribosomal subunit (sensu Eukarya) - protein biosynthesis
             h/ps/rp
40S ribosomal protein S11                   8E-56 40S ribosomal protein S11
                                                                    9E-065 Translation,Ribosomal_S17
                                                                                            ribosomal structure and biogenesis
                           embryonic development (sensu Animalia) - physiological process - reproduction 1E-019 EPEND                       0.066
             h/ps/rp
60S ribosomal protein L36                   3E-42
                           structural constituent of60S ribosomal protein L36
                                                       ribosome - protein biosynthesis - cytosolic large ribosomal3E-026 (sensu Eukarya)
                                                                    3E-027 Translation,Ribosomal_L36e
                                                                                            ribosomal structure and subunit DZF
                                                                                                                      biogenesis            0.061
             h/ps/rp
40S ribosomal protein S13                   1E-59 40S ribosomal protein S13
                                                                    2E-065 Translation,Ribosomal_S15
                                                                                            ribosomal Nematoda)1E-014 -PAX
                           embryonic development (sensu Animalia) - larval development (sensustructure and- biogenesisgrowth reproduction 0.019
             h/ps/rp
40S ribosomal protein S14                   2E-72 - cytosolic small ribosomal
                                                                    2E-060 Translation, (sensu Eukarya)
                                                                                            ribosomal structure andbinding
                                                                                                                      biogenesis
                           intracellular - ribosome 40S ribosomal protein S14 subunit Ribosomal_S11 - RNA1E-030 - protein biosynthesis
             h/ps/rp
60S ribosomal protein L26                   2E-46 - cytosolic large ribosomal
                                                                    9E-031 Translation,KOW  ribosomal structure and0.077 SRA
                                                                                                                      biogenesis
                           intracellular - ribosome 60S ribosomal protein L26 subunit (sensu Eukarya) - RNA binding - protein biosynthesis  0.047
             h/ps/rp
60S ribosomal protein L35                   5E-45 60S ribosomal protein L35
                                                                    7E-020 Translation,Ribosomal_L29nucleolus - cytosolic
                                                                                             biosynthesis -         2E-006
                           mRNA binding - structural constituent of ribosome - protein ribosomal structure and biogenesis large ribosomal subunit (sensu Eukary
             h/ps/rp       RNA               structural constituent of ribosome -
                                                                    2E-024 Translation,Ribosomal_L14e
                                                                                            ribosomal structure and biogenesis
                                                                                                                    3E-012
60S ribosomal protein L14 binding -1E-33 60S ribosomal protein L14 protein biosynthesis - cytosolic large ribosomal subunit (sensu Eukarya)
             h/ps/rp
60S ribosomal protein L10A                  1E-83 60S ribosomal protein L10A
                                                                    6E-081 Translation,Ribosomal_L1
                                                                                            ribosomal structure and development (sensu Nematoda) - growth - reprod
                                                                                                                    6E-042
                           embryonic development (sensu Animalia) - positive regulation of growth rate - larvalbiogenesis
             h/ps/rp       RNA               structural constituent of ribosome -
                                                                    6E-070 Translation,Ribosomal_L18e
                                                                                            ribosomal structure and biogenesis
                                                                                                                    6E-060
60s ribosomal protein L18 binding -5E-74 60s ribosomal protein L18 protein biosynthesis - cytosolic large ribosomal subunit (sensu Eukarya)
             h/ps/rp
40S ribosomal protein S7                    2E-68 - cytosolic small ribosomal
                                                                    4E-061 Translation, (sensu Eukarya)
                                                                                            ribosomal structure and biogenesis
                                                                                                                    5E-061
                           intracellular - ribosome 40S ribosomal protein S7 subunit Ribosomal_S7e - structural constituent of ribosome - RNA binding - protein
             h/ps/rp
60s ribosomal protein L39                   4E-18 60s ribosomalribosomalTranslation,Ribosomal_L39structural biogenesis of ribosome
                                                                      protein subunit (sensu Eukarya) -
                           protein biosynthesis - cytosolic large 5E-007 L39                                        1E-005
                                                                                            ribosomal structure and constituent
             initiation factor 1 (eIF-1/SUI1) factor activity - initiation factor 1 (eIF-1/SUI1)
Translation h/ps                            5E-44 Translation regulation of translational initiation structure and and/or maintenance - cytoplasm - translation factor
                           translation initiation                   4E-045 Translation,SUI1                         2E-026
                                                                                            ribosomal - cell growth biogenesis
             h/ps                            structural constituent of ribosome - protein biosynthesis - cytosolic small ribosomal subunit (sensu Eukarya)
                                                                    5E-077
Ribosomal protein S7 RNA binding -5E-98 Ribosomal protein S7 Translation,Ribosomal_S7                               4E-043
                                                                                            ribosomal structure and biogenesis
             h/ps          positive regulation of growth rate translation initiation (sensu Nematoda) - growth 1E-005 eIF1a
                                            3E-29 Predicted         6E-029 Translation,eIF-1a to eIF-1A
                                                                                             related                - gametogenesis
Predicted translation initiation factor related to eIF-1A - larval developmentfactorribosomal structure and biogenesis                    5E-023
             h/ps          RNA binding -4E-64 60s ribosomal protein L15/L27
60s ribosomal protein L15/L27                                       1E-050 Translation,L15  ribosomal structure and biogenesis
                                                                                                                    3E-006
                                             structural constituent of ribosome - protein biosynthesis - cytosolic large ribosomal subunit (sensu Eukarya)
             h/ps
40S ribosomal protein S25                   8E-39 40S rate          3E-027 Translation,Ribosomal_S25
                           positive regulation of growthribosomal protein S25                                       2E-029 HTH_GNTR 0.024
                                                                                            ribosomal structure and biogenesis
             h/ps
60S ribosomal protein L44                   6E-50 60S ribosomal protein L44
                                                                    1E-028 Translation,Ribosomal_L44
                                                                                            ribosomal Nematoda)9E-019 - reproduction
                           embryonic development (sensu Animalia) - larval development (sensustructure and- biogenesisgrowth
             h/ps                            - physiological process - reproduction
                                                                    2E-056
Ribosomal protein S18 mitochondrion1E-68 Ribosomal protein S18 Translation,Ribosomal_S13                            5E-030
                                                                                            ribosomal structure and biogenesis
             h/ps
40S ribosomal protein S26                   3E-42 40s ribosomal protein S26
                                                                    4E-034 Translation,Ribosomal_S26e
                                                                                            ribosomal structure and biogenesis
                                                                                                                    5E-039
                           positive regulation of body size - embryonic development (sensu Animalia) - embryonic morphogenesis - larval development (sensu N
             h/ps                           5E-57 40S ribosomal - growthTranslation,Ribosomal_S9
                                                                    2E-067
ribosomal protein S16 larval development (sensu Nematoda) protein S16                       ribosomal structure and biogenesis
                                                                                                                    1E-036
                                                                                - physiological process - reproduction
             h/ps                            structural constituent of ribosome - protein biosynthesis - cytosolic large ribosomal subunit (sensu Eukarya)
ribosomal protein L18a RNA binding -2E-70 60S ribosomal protein L18A                        ribosomal structure     7E-064
                                                                    2E-062 Translation,Ribosomal_L18ae and biogenesis
             h/ps          RNA               structural constituent of ribosome -
                                                                    3E-046 Translation,Ribosomal_L7Ae
                                                                                            ribosomal structure and biogenesis
                                                                                                                    2E-021
40S ribosomal protein S12 binding -2E-54 40S ribosomal protein S12 protein biosynthesis - cytosolic small ribosomal subunit (sensu Eukarya)
             h/ps                           3E-25 40S ribosomal protein S21
                                                                    2E-029 Translation,Ribosomal_S21e
                                                                                            ribosomal Nematoda)5E-029 - physiological process - reproduction
ribosomal protein S21 embryonic development (sensu Animalia) - larval development (sensustructure and- biogenesis     growth
             h/ps          larval           5E-41 40S ribosomal - growthTranslation,Ribosomal_S24e
40S ribosomal protein S24 development (sensu Nematoda) protein S24  7E-040                  ribosomal structure and biogenesis
                                                                                                                    2E-023
                                                                                - physiological process - reproduction
             h/ps          structural protein S21
                                            1E-21                                          Ribosomal_S21             0.055
possible mitochondrial ribosomal constituent of ribosome - protein biosynthesis - mitochondrial small ribosomal subunit
             h/ps          oviposition         0       development 1E-129 Signal transduction mechanisms 3E-006 WD40
                                                                      subunit-like protein WD40                                           2E-007
G protein beta subunit-like protein - embryonic G protein beta(sensu Animalia) - positive regulation of growth rate - positive regulation of locomotion
             h/ps
40S ribosomal protein S19                   5E-51 - protein biosynthesis Translation,Ribosomal_S19e
                                                                    6E-054
                           intracellular - ribosome 40S ribosomal protein S19                                       8E-056 HTH_DTXR 5E-004
                                                                                            ribosomal structure and biogenesis
             h/ps
40S ribosomal protein S19                   5E-51 - protein biosynthesis Translation,Ribosomal_S19e
                                                                    6E-054
                           intracellular - ribosome 40S ribosomal protein S19                                       8E-056 HTH_DTXR 5E-004
                                                                                            ribosomal structure and biogenesis
             h/ps          protein          acid glycosylation response protein
                                                                    2E-022 Function unknownRAMP4                    2E-022
Predicted membrane protein amino 3E-19 Predicted-membraneto stress - plasma membrane organization and biogenesis - endoplasmic reticulum - ribos
             h/ps                            structural constituent of ribosome - protein biosynthesis - cytosolic small ribosomal subunit3E-005 Eukarya)
                                                                    7E-063
Ribosomal protein S4 RNA binding -4E-87 Ribosomal protein S4 Translation,Ribosomal_S4                               1E-014 S4
                                                                                            ribosomal structure and biogenesis             (sensu
             h/ps          positive regulation of growth rate
                                            7E-24                   3E-020 Translation,Ribosomal_S30
                                                                                            ribosomal structure and biogenesis, Posttranslational modification, protein
Ubiquitin-like/40S ribosomal S30 protein fusionUbiquitin-like/40S ribosomal S30 protein fusion                      3E-020 UBQ            5E-008
             h/ps                        0.000003
ribosomal protein L41 protein biosynthesis - cytosolic large ribosomal subunit (sensu Eukarya) - structural constituent of ribosome
           h/ps                       2E-74      activity - tRNA aminoacylation for tRNA_bind structure and biogenesis
                                                               protein               ribosomal            5E-027
tRNA-binding protein tRNA binding - cytokinetRNA-binding 1E-060 Translation,protein translation - chemotaxis - inflammatory response - signal transductio
           h/ps       positive L55 2E-12 Mitochondrial 4E-022 Translation, ribosomal structure and biogenesis
Mitochondrial ribosomal protein regulation of growth rate      ribosomal protein L55

            h/prot      protein Pno1p6E-66 Predicted RNA-binding Posttranslational modification, Nob1p and involved in 26S proteasome assembly
                                                             7E-083 protein Pno1p interacting with protein turnover, chaperones
Predicted RNA-binding gametogenesisinteracting with Nob1p and involved in 26S proteasome assembly                        KH   1E-004
            h/prot      ubiquitin conjugating Ubiquitin-protein ligase
                                                              - ubiquitin-protein ligase activity - protein modification UBCc
                                                                                      UQ_con                  2E-038
ubiquitin-conjugating enzyme E2L 3 1E-40 enzyme activity 6E-063 Posttranslational modification, protein turnover, chaperones  3E-040
            h/prot      embryonic development (sensu Animalia) - reproduction ribosomal
                                       fusion                 ribosomal protein S27a fusion
Ubiquitin/40S ribosomal protein S27a 3E-36 Ubiquitin/40S 1E-061 Translation,ubiquitin structure and biogenesis7E-025 UBQ      1E-024
            h/prot       protein large2E-25 Ubiquitin/60s 9E-035 Translation,Ribosomal_L40e
                                        ribosomal subunit (sensu Eukarya)
Ubiquitin/60s ribosomalcytosolicL40 fusion                                             fusion                 7E-019 UBQ
                                                             ribosomal protein L40 ribosomal structure and biogenesis         8E-016

             h/pm                        7E-39       - amine metabolism - cytoplasm Sulfotransfer_1 only
Sulfotransferase sulf sulfotransferase activitySulfotransferase   2E-048 General function prediction                3E-036
             h/pm                        4E-25 Sulfotransferase   1E-042                 Sulfotransfer_1
Sulfotransferase sulf sulfate assimilation - sulfotransferase activity General function prediction only             2E-033 PTPc_motif 0.024
             h/pm pox extracellular space - procollagen-proline 4-dioxygenase activity - peptidyl-proline hydroxylation to 4-hydroxy-L-proline
                                         6E-17
Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-2 subunit                                                              HEPN             0.002
             h/pm pox mitochondrion5E-79 Protein disulfide
                                          - positive regulation of6E-058 Posttranslational modification, subunit)
                                                                   body size             Thioredoxin                5E-026
Protein disulfide isomerase (prolyl 4-hydroxylase beta subunit) isomerase (prolyl 4-hydroxylase beta protein turnover, chaperones
             h/pm pox extracellular space - procollagen-proline 4-dioxygenase activity - peptidyl-proline hydroxylation to 4-hydroxy-L-proline
                                         1E-26 Prolyl 4-hydroxylase Amino acid
                                                                  2E-007
Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-2 subunit alpha subunit transport and metabolism                       HEPN             0.008
             h/pm pox procollagen-proline           Prolyl 4-hydroxylase alpha subunit 2OG-FeII_Oxy
                                                                  2E-049 Amino acid transport
Prolyl 4-hydroxylase alpha subunit 7E-614-dioxygenase activity - endoplasmic reticulum and metabolism                0.001 P4Hc               1E-032
             h/pm pe
Signal peptidase subunit                 4E-25 Signal proteolysis and peptidolysisSPC12 peptidase complex - integral to endoplasmic reticulum membrane
                                                                  5E-025 Intracellular - signal
                         molecular_function unknown - peptidase subunit                                             8E-022
                                                                                           trafficking, secretion, and vesicular transport
             h/pm gamma carboxy glutamate formation
Vitamin K epoxide reductase complex
             h/pm        cytosol         4E-74 Cyclophilin type peptidyl-prolyl cis-trans isomerase
Cyclophilin type peptidyl-prolyl cis-trans isomerase                                     Pro_isomerase              3E-069
                                                                  2E-075 Posttranslational modification, protein turnover, chaperones
             h/pm        peptidyl-prolyl 6E-18
                                          cis-trans isomerase peptidyl-prolyl cis-trans FKBP_C
                                                                  6E-028 Posttranslational - ribosome assembly
                                                                                          isomerase                 4E-020
FKBP-type peptidyl-prolyl cis-trans isomerase FKBP-type activity - nucleus - cytoplasm modification, protein turnover, chaperones
             h/pm        integral to death
                                         9E-40 microsome - oligosaccharyl protein/oligosaccharyltransferase, protein amino acid glycosylation - anti-apoptosis
                                                                  5E-034 Cell transferase complex - apoptosis - epsilon subunit
                                                                                         DAD                        9E-032
defender against programmed cellmembrane - Defender against cell death cycle control, cell division, chromosome partitioning, Posttranslational modification
             h/pm
Alpha crystallins                        2E-23 Alpha crystallins  9E-030 sensory organ development
                                                                                         HSP20                      4E-019
                         heat shock protein activity - response to heat - Posttranslational modification, protein turnover, chaperones
             h/pm        protein binding - biological_process unknown - protein function prediction only
chaperone TPR repeat-containing protein                           3E-057 cellular_component unknown
                                         1E-75 TPR repeat-containing General             TPR                        6E-006 TPR                7E-007
             h/pm        dolichyl-diphosphooligosaccharide-protein glycotransferase activity - endoplasmic 1E-051
Oligosaccharyltransferase, beta subunit                           2E-048 Posttranslational
                                                                                         DDOST_48kD                 reticulum
                                         2E-51 Oligosaccharyltransferase, beta subunit modification, protein turnover, chaperones
thioredoxin h/pm                                                  1E-031                 Thioredoxin                5E-021
                         mitochondrion8E-29 Thioredoxin-like proteinPosttranslational modification, protein turnover, chaperones
             h/pm        mitochondrion 0
Oligosaccharyltransferase, gamma subunit                          1E-084 Posttranslational modification, protein turnover, chaperones
                                                                                           subunit
                                                    Oligosaccharyltransferase, gammaOST3_OST6                       6E-089
             h/pm
Alpha crystallins        mitochondrion9E-16 Alpha crystallins                            HSP20                      4E-015
                                                                  4E-021 Posttranslational modification, protein turnover, chaperones
thioredoxin h/pm                         2E-25       intermediate 1E-024 - cell motility - signal transduction - cell-cell signaling - cell proliferation
                                                                  activity               Thioredoxin                2E-025
                         thiol-disulfide exchangeThioredoxin-like proteinPosttranslational modification, protein turnover, chaperones
             with        anchor
Trypsin-like h/pm signal brush border 3E-10 Trypsin                                       transport
                                                                  8E-020 Amino acid Trypsin and metabolism          5E-013 Tryp_SPc           4E-026

            h/pe      complex TRAP, binding - cotranslational membrane targeting -beta subunit reticulum - integral to membrane
                                      3E-51 Translocon-associated IntracellularTRAP_betasecretion, and vesicular transport
Translocon-associated signal sequence beta subunit                                   trafficking,
                                                             5E-045 complex TRAP, endoplasmic                 1E-049
            h/pe      extracellular 4E-14 Uncharacterized conserved protein metabolism
                                      molecular_function unknown - carboxylic acid
                                                             1E-012 Function unknown
ER cargo complex protein similar to -multiple coagulation factor deficiency 2
            h/pe      extracellular 2E-13 Uncharacterized conserved protein metabolism
                                      molecular_function unknown - carboxylic acid
                                                             3E-012 Function unknown
ER cargo complex protein similar to -multiple coagulation factor deficiency 2
V-SNARE h/pe                          1E-22 V-SNARE          2E-021 IntracellularSNARE
                                                                                     trafficking, secretion, and vesicular transport 6E-008
                                                                                                              3E-008 t_SNARE
                      Golgi membrane - integral to membrane - molecular_function unknown - vesicle-mediated transport
            h/pe      extracellular 9E-13 Uncharacterized conserved protein metabolism
                                      molecular_function unknown - carboxylic acid
                                                             1E-013 Function unknown
ER cargo complex protein similar to -multiple coagulation factor deficiency 2
            h/pe                                              SNX11
Sorting nexin SNX11 endocytosis 1E-67 Sorting nexin 5E-055 IntracellularPX                                    7E-020 PX
                                                                                     trafficking, secretion, and vesicular transport 2E-017
            h/pe      embryonic       1E-40 Signal peptidase complex subunit SPC22
                                                             3E-056 Intracellular trafficking, secretion, and vesicular transport
                                                                                                              1E-057
Signal peptidase complex subunit development (sensu Animalia) - positive regulation of growth rate - larval development (sensu Nematoda) - physiological p
            h/pe      complex TRAP, delta subunit
                                      5E-39 Translocon-associated IntracellularTRAP-deltasecretion, and vesicular transport
                                                             4E-041 complex TRAP,    trafficking,
Translocon-associated calcium ion binding - intracellular protein transport - translocon delta subunit        4E-043
            h/pe      small monomeric 2E-96 GTP-binding ADP-ribosylation factor Arf1
                                                             2E-087 IntracellularArf trafficking, secretion, and vesicular transport 1E-095
                                                                                                              9E-077 ARF
GTP-binding ADP-ribosylation factor Arf1GTPase activity - GTP binding - protein amino acid ADP-ribosylation - ARF small monomeric GTPase activity - prote

          superoxide cytoplasm -SOD1
Cu2+/Zn2+ h/ox                      9E-57 Cu2+/Zn2+ superoxide Inorganic ion transport and metabolismoxidative stress - removal of superoxide radicals
                                                        3E-051 dismutase SOD1 Sod_Cu                  to
                      dismutase mitochondrion - copper, zinc superoxide dismutase activity - response2E-057
          h/organelar integral to membrane - Membrane protein involved in organellar division
                       division     3E-41 mitochondrion
Membrane protein involved in organellar division        2E-035 Cell wall/membrane/envelope biogenesis

              cycle      biological_process unknown - molecular_function unknown - cellular_component unknown
cell division h/nr 2 homolog -like      0.002
              h/nr
P8 nuclear protein       nucleus                             3E-011 Transcription
                                      0.000001 DNA-binding nuclear protein p8
              h/nr       embryonic development (sensu H4 2E-038 Chromatin structure and dynamics 9E-008 H4 (sensu 7E-030
similar to germinal histone H4                                                    Histone
                                        3E-53 Histone Animalia) - positive regulation of growth rate - larval development Nematoda) - growth - physio
              h/nr                      1E-50 Histone Animalia) - larval development (sensu dynamics - growth locomotory behavior
                                                                                  Histone
similar to Histone H2B embryonic development (sensu H2B 9E-038 Chromatin structure andNematoda)3E-025 -H2B                1E-035
              h/nr       chromatin binding - nucleus
                                        1E-54 Heterochromatin-associated protein HP1 and related CHROMO domain proteins 1E-017
                                                             6E-023 Chromatin Chromo_shadow
Heterochromatin-associated protein HP1 and related CHROMO domain proteins structure and dynamics 6E-018 ChSh
              h/nr                      1E-75 Translin family- protein General function prediction only
                                                               RNA
Translin family protein cytoplasm - nucleus - protein binding2E-068 binding       Translin                 8E-035

           h/met nuc response to protein involved nucleus molecular_function unknown - processing 2E-005 AAA
                                    8E-37 Predicted nucleotide kinase/nuclear protein and metabolism stress response
                                                             9E-068 Nucleotide AAA                        of
Predicted nucleotide kinase/nuclearoxidative stress -oxidative -stress response transport involved oxidative20S pre-rRNA           1E-004
           diphosphate kinase       7E-51 Nucleoside diphosphate kinase transport and metabolism
                                                             1E-047 Nucleotide NDK                        4E-057 NDK               5E-055
Nucleoside h/met nuc transcription factor activity - nucleoside-diphosphate kinase activity - ATP binding - regulation of transcription, DNA-dependent - negat

            h/met involved in organellar division
                                    3E-41 mitochondrion       2E-035 Cell wall/membrane/envelope biogenesis
Membrane proteinem integral to membrane - Membrane protein involved in organellar division
            h/met em containing protein similar to conserved hematopoietic stem/progenitor cells protein - may beZnF_CDGSH8E-011
                                                              Zn-finger containing protein
CDGSH-type Zn-finger mitochondrion8E-25 CDGSH-type 5E-026 General function prediction only                              housekeeping protein
            h/met em mitochondrion subunit
Succinate dehydrogenase, Fe-S protein0                        1E-125 Energy production and conversion
                                                Succinate dehydrogenase, Fe-S protein subunit
            h/met em protein-mitochondrial Mitochondrial 8E-050 inner membrane translocase, subunit 1E-031 complex - integral to membrane
                                      translocase, subunit TIM17
                                                              import inner membrane presequence translocase
                                                                                    trafficking, secretion, and vesicular transport
Mitochondrial import inner membrane7E-64 targeting - mitochondrial IntracellularTim17                        TIM17
            h/met em cytochrome-c 1E-85 activity
                                     oxidase Cytochrome oxidase subunit IIIproduction and conversion 1E-078
                                                              7E-066 Energy and related proteins
                                                                                   COX3
Cytochrome oxidase subunit III and related proteins - mitochondrial electron transport, cytochrome c to oxygen
            h/met em carrier proteins 0         Mitochondrial 1E-133 Energy production and conversion 7E-021
                                                              ADP/ATP carrier proteins
                                                                                   Mito_carr
Mitochondrial ADP/ATPmolecular_function unknown - mitochondrial inner membrane - mitochondrial transport
            h/met em mitochondrion - NADH dehydrogenase activity
                                      alpha
NADH dehydrogenase (ubiquinone) 12E-17 subcomplex, 4
            h/met em proton-transporting d/ATP7
                                    5E-38 Mitochondrial 7E-028 Energy production and conversion -3E-033 Hr1
                                                              F1F0-ATP synthase, Mt_ATP-synt_D
                                                                                     F(o) (sensu Eukarya) hydrogen-exporting ATPase activity, phosphorylativ
Mitochondrial F1F0-ATP synthase, subunit ATP synthase complex, coupling factorsubunit d/ATP7                                        0.032
            h/met em reductase (6.4kD) subunit
ubiquinol-cytochrome c mitochondrion4E-07
            h/met em ATP-binding cassette (ABC) transporter activity - ER protein translocation complex - transport -transport to drug - membrane fraction
NADH dehydrogenase 6                                           0.063 Intracellular trafficking, secretion, and
                                     0.003 Membrane component of transporter activity - ATP binding vesicular response
            h/met em transporter subunit membrane fraction
                                       6E-42 Mitochondrial 2E-030 Energy production synthase complex (sensu
                                                                F1F0-ATP synthase, ATP-synt_C
                                                                                      subunit c/ATP9/proteolipid
Mitochondrial F1F0-ATP synthase,activity - c/ATP9/proteolipid - proton-transporting ATP and conversion 5E-011 Eukarya) - mitochondrial inner membrane
            h/met subunit 6 synthesis1E-29 ATP synthase F0- subunit 6 and related proteins
                                        coupled proton transport proton-transporting ATPand conversion 5E-019
ATP synthase F0 em ATP and related proteins                                           ATP-synt_A
                                                               8E-022 Energy production synthase complex, coupling factor F(o) (sensu Eukarya)
            h/met em subunit II, andoxidase proteins
                                        related Cytochrome c3E-070 Energy production andproteins
                                                                oxidase, subunit II, and related conversion 4E-057
                                                                                      COX2
Cytochrome c oxidase, cytochrome-c 2E-56 activity - mitochondrial electron transport, cytochrome c to oxygen
            h/met em subunit I            0      Cytochrome c6E-065 Energy production and conversion 1E-159
                                                                oxidase, subunit I COX1
Cytochrome c oxidase, cytochrome-c oxidase activity - mitochondrial electron transport, cytochrome c to oxygen
            h/met em embryonic subunit e Mitochondrial 3E-010 Energy production and conversion 6E-014
                                      0.00002                   F1F0-ATP synthase, ATP-synt_E
                                                                                      subunit e
Mitochondrial F1F0-ATP synthase,development (sensu Animalia) - positive regulation of growth rate - larval development (sensu Nematoda) - growth
Cytochrome c                           1E-38 Cytochrome c5E-040                       Cytochrom_C
            h/met em electron transporter activity - mitochondrion Energy production and conversion 2E-008
            h/met em mitochondrion 0.002 Mitochondrial 3E-005 Energy production and conversion
                                        - proton-transporting F1F0-ATP synthase, ATP-synt_Eps
                                                                                       (sensu Eukarya) - hydrolase activity - hydrogen ion transporter activity - hy
Mitochondrial F1F0-ATP synthase, subunit epsilon/ATP15 ATP synthase complexsubunit epsilon/ATP15 6E-005
            h/met em proton-transporting b/ATP4
                                       6E-68 Mitochondrial 3E-056 Energy production and conversion -2E-061 MYSc
                                                                F1F0-ATP synthase, Mt_ATP-synt_B
                                                                                       F(o) (sensu Eukarya) hydrogen-exporting ATPase activity, phosphorylativ
Mitochondrial F1F0-ATP synthase, subunit ATP synthase complex, coupling factorsubunit b/ATP4                                           0.097
            h/met em integral to membrane mitochondrionF1F0-ATP synthase, subunit f
                                       5E-12
Mitochondrial F1F0-ATP synthase, subunit f - Mitochondrial 5E-030 Energy production and conversion
            h/met em transporter subunit membrane fraction - proton-transporting ATP and conversion 3E-013 Eukarya)
                                       2E-32 Mitochondrial 2E-034 Energy production synthase complex (sensu
Mitochondrial F1F0-ATP synthase,activity - delta/ATP16                                subunit delta/ATP16
                                                                F1F0-ATP synthase, ATP-synt_DE_N
            h/met oxidoreductase NDUFA2/B8NADH:ubiquinone oxidoreductase NDUFA2/B8conversion 2E-021
                                       1E-23       subunit     2E-027 Energy production and subunit
                                                                                      L51_S25_CI-B8
NADH:ubiquinoneem NADH dehydrogenase (ubiquinone) activity - energy pathways - membrane fraction
            h/met em reductase, subunit
Ubiquinol cytochrome cmitochondrion4E-22QCR8                   3E-022 reductase, UcrQ QCR8
                                                                                      subunit
                                                 Ubiquinol cytochrome cEnergy production and conversion 2E-023
            h/met em subunit IV/COX5b  oxidase Cytochrome c1E-045 Energy production and conversion 3E-042
                                                                oxidase, subunit IV/COX5b
Cytochrome c oxidase, cytochrome-c 5E-31 activity - energy pathways                   COX4
            h/met em osmoregulation - embryonic development (sensu membrane anchor regulation of1E-024 rate - larval development (sensu Nematoda)
                                        anchor Succinate related proteins
                                                               2E-019 Energy production and conversion, Intracellular trafficking, secretion, and vesicular tran
                                                                                      CybS                     growth
Succinate dehydrogenase membrane1E-18 subunit anddehydrogenase Animalia) - positive subunit and related proteins
            h/met em integral to membrane
Cytochrome c oxidase subunit VIIa 2E-07 - mitochondrion                               COX7a                    3E-009
cox 6                                  8E-11                                          COX6C                    1E-013
            h/met em extracellular space - inner membrane - integral to membrane - mitochondrion - respiratory chain complex IV (sensu Eukarya) - oxidore
            h/met em subunit Vb/COX4   of adult Cytochrome c7E-031 Energy production and conversion Animalia) - positive regulation of growth rate - lipid
                                                                oxidase, subunit Vb/COX4
                                                                                      COX5B
Cytochrome c oxidase, determination 1E-25 life span - osmoregulation - embryonic development (sensu5E-016
            h/met em beta-ketoacyl-ACP reductase               1E-046 beta-ketoacyl-ACP reductase
                                                                                      adh_short
Mitochondrial/plastidial mitochondrion6E-41 Mitochondrial/plastidial Lipid transport and metabolism            5E-043
            h/met em carrier proteins  4E-56 Mitochondrial 6E-049 Energy production and conversion 9E-011
                                                                ADP/ATP carrier proteins
                                                                                      Mito_carr
Mitochondrial ADP/ATPmolecular_function unknown - mitochondrial inner membrane - mitochondrial transport
            h/met em dehydrogenase     5E-67 NAD-dependent malateEnergy production and conversion 1E-034
                                                               8E-062     dehydrogenase
                                                                                      Ldh_1_C
NAD-dependent malateL-malate dehydrogenase activity - biological_process unknown - mitochondrial matrix
            h/met em mitochondrion4E-22 Mitochondrial 1E-024 Energy production and conversion 4E-018
Mitochondrial F1F0-ATP synthase, subunit g/ATP20                                      subunit g/ATP20
                                                                F1F0-ATP synthase, ATP-synt_G
            h/met em oxaloacetate carrier
                                       1E-30 Mitochondrial 7E-048 Energy production and conversion 1E-009
                                                                oxaloacetate carrier protein
                                                                                      Mito_carr
Mitochondrial oxaloacetate carrier protein activity - sulfate porter activity - oxaloacetate transport - sulfate transport - mitochondrial inner membrane
            h/met oxidoreductase, NDUFA10/42kDa subunit5E-086 Energy production and conversion 4E-014 AAA
                                       5E-60 NADH:ubiquinone - positive regulation    NDUFA10/42kDa - larval                           0.008
NADH:ubiquinoneem embryonic development (sensu Animalia) oxidoreductase, dNKof growth rate subunit development (sensu Nematoda) - growth
            h/met aa dopachrome isomeraseMacrophage migration Defense factor
                                       8E-12      activity     6E-017                 MIF
D-dopachrome tautomerase - Macrophage migration inhibitory factor inhibitory mechanisms                        2E-019
            h/membrane embrane fraction - integral to membrane
                         m             1E-20      - transmembrane
                                                                0.061 Signal transduction mechanisms
similar to Thymic dendritic cell-derived factor 1Neurexin III-alpha protein

           h/imm       peptidoglycan 2E-22
                                       receptor                                    Amidase_2             6E-015 PGRP           2E-026
peptidoglycan recognition protein, truncated activity - detection of bacteria - innate immune response - defense response to Gram-positive bacteria - intrace

            h/ext matrixnucleocytoplasmic transporter activity0.037 RNA processing and modification 0.041
                                       4E-09 U3                - nuclear pore - nucleocytoplasmic transport
                                                                                    Mpp10
probable cuticle protein - contains gygy repeats small nucleolar ribonucleoprotein (snoRNP) subunit - Mpp10p
            h/ext matrixnucleocytoplasmic transporter activity - nuclearTranscription porozoite_P67
cuticle/mucin                                                1E-004      pore - nucleocytoplasmic transport 0.097
                                                                                    S
                                       3E-12 Dosage compensation complex, subunit MLE
            h/cut         binding domain
                                       0.015
cuticle/mucin with chitinbiological_process unknown - molecular_function unknown    Chitin_bind_4         4E-006

           h/cs         embryonic development (sensuessential light Cytoskeletonfhand
                                        protein Myosin Animalia)                    e
Myosin essential light chain, EF-Hand2E-45 superfamily 1E-055 chain, EF-Hand protein superfamily 0.008 EFh                            0.002
           h/cs         positive regulation controlled tumor protein) Cell cycle control, cell division, chromosome
                                       8E-29 Microtubule-binding protein locomotory behavior
                                                               3E-034               TCTP                     4E-042
Microtubule-binding protein (translationallyof growth rate - gametogenesis -(translationally controlled tumor protein) partitioning, Cytoskeleton
                         Clustered               Clustered             Clustered             Clustered
                          at 60%-                 at 70%-               at 80%-               at 90%-              Clustered
  Best                    Sim- on                 Sim- on               Sim- on               Sim- on                by PSI-
match to                  60% of                  60% of                60% of                60% of                blast - 4
 ACARI                   length - -              length - -            length - -            length - -            iteraction
database     E value     Cluster#       # seqs   Cluster#     # seqs   Cluster#     # seqs   Cluster#     # seqs        s       # seqs


               6.0         199
heat shock protein 82 [Platynothrus p     1         264         1         339         1         372         1         186         1

               5E-010         107
heat shock protein 82 [Steganacarus m 1           142           1         178         1         193         1          1         187
                 5.1          193
p8/25-4 [Amblyomma americanum] 22 5.1     1       257           1         332         1         365         1         179         1
                 1.1          175         1
NADH dehydrogenase 4 [Carios capensis] 24 1.1     236           1         310         1         343         1         158         1
                0.016
Mag29 [Dermatophagoides174     farinae]           235
                                          1 30 0.016            1         309         1         342         1         157         1
                 1.6          170
ferritin [Hyalomma asiaticum asiaticum] 1 23 1.6230             1         303         1         336         1         151         1
                 3.2
group 14 allergen protein [ 155           1       209           1         267         1         293         1         143         1
                 2.1
salivary secreted protein [ 154           1       208           1         266         1         291         1         141         1
                 9.6          152
cytochrome oxidase subunit I [Uropode 1           204           1         262         1         287         1         138         1
                 1.8          144
putative secreted salivary gland pept 1           195           1         248         1         268         1         134         1
                 1.7            1
NADH dehydrogenase subunit 3 [Boophilu   306       1           105        60          1         53          1         32          1
                0.87          219
cytochrome oxidase III [Ixodes scapula 1          301           1         390         1         435         1         209         1
                 8.9
block of proliferation protein41[Ixode    2       54            2         55          2         46          2         28          2
                0.081         121
heat shock protein 82 [Steganacarus m 1           160           1         204         1         219         1         107         1
                               99         1       132           1         161         1         169         1         86          1
                0.64           25
angiotensin-converting enzyme-like pro 2          127           1         156         1         164         1         156         1
               4E-040         241
fed tick salivary protein 1 [Ixodes s     1       325           1         417         1         465         1         227         1
               4E-049
hypothetical protein [Ixodes 37           183 4e-049
                               pacificus] 2       285           1         367         1         408         1         197         1
               3E-083         239
fed tick salivary protein 6 [Ixodes s     1       323           1         414         1         462         1         226         1

               1E-111          1
fed tick salivary protein 7 [Ixodes s    306        322         1         413         1         461         1         225         1

               0.76        190
cytochrome oxidase iii [Carios capen 1           254            1         329         1         362         1         176         1
              0.089        177
heat shock protein 82 [Tectocepheus m 1          238            1         312         1         345         1         160         1
                4.8          1
unnamed protein product [Ixodes rici 306         206            1         264         1         289         1         140         1
                1.1
putative secreted carboxype 55           1       77             1         85          1         83          1         46          1
                2.3
RNA polymerase III [Ixodes10 scapularis] 4 23 2.3308            1         398         1         446         1         215         1

            0.55         2
Mag44 [Dermatophagoides farinae]                   169
                                          12 27 0.55            1         215         1         230         1         115         1

               3E-098
tetraspanin-like protein [D 124           1         166         1         212         1         227         1         112         1

              1E-020      201
cystatin [Lepidoglyphus destructor]       90     267
                                          1 1e-020              1         342         1         375         1         189         1
               0.68        58
complement inhibitor precursor [Ornit     1       81            1         90          1         90          1         51          1
                0.0       254
alpha-2-macroglobulin [Ixod               1      354            1         456         1         509         1         239         1

              1E-061       198                    263
ribosomal protein L30 [Ixodes pacificus] 1 226 1e-061           1         338         1         371         1         185         1
                           196           1        261           1         336         1         369         1         183         1
                3.9
group 14 allergen protein [ 1          306        260           1         335         1         368         1         182         1
                6.3        194
heat shock protein 82 [Steganacarus m 1           258           1         333         1         366         1         180         1
                 8.1
Bm95 protein [Boophilus mic  191           1        255    1   330   1   363   1   177   1
               5E-088        187                    251
ribosomal protein L12 [Ixodes pacificus] 1 314 5e-088      1   326   1   359   1   173   1
                 2.0
putative secreted histamine 1   binding p 306       39     2   324   1   357   1   171   1
                0.71         186
putative sodium channel [Boophilus mic1             249    1   323   1   356   1   170   1
               4E-058
ribosomal protein, large P2184 [Ixodes p 1          247    1   321   1   354   1   168   1
               1E-152
60S ribosomal protein L7A 181 [Ixodes pac 1         243    1   317   1   350   1   164   1
                             180           1        242    1   316   1   349   1   163   1
               1E-011
ribosomal protein, large P2 38 [Ixodes p 2          241    1   315   1   348   1   162   1
               8E-043        179
ribosomal protein S4 [Ixodes pacificus] 1 165 8e-043240    1   314   1   347   1   161   1
                 8.1
high molecular weight allerg 176           1        237    1   311   1   344   1   159   1
                              37           2        233    1   307   1   340   1   155   1
                             172           1        232    1   306   1   339   1   154   1
BTSP-5 [Ixodes1.3 pacificus] 228           1
                                          25 1.3    311    1   401   1   449   1   217   1
                 8.7         223
putative immunoglobulin-binding prote 1             305    1   395   1   443   1   212   1
                             218           1        298    1   387   1   432   1   207   1
                 8.5         217
chitinase [Haemaphysalis longicornis] 1 21 8.5 297         1   386   1   431   1   206   1
                 4.1          24
RNA polymerase II largest subunit [ta 2             34     2   35    2   429   1   21    2
                 5.9         214
unknown protein [Ixodes scapularis]        1 23 5.9 294    1   382   1   426   1   204   1
                              40           2        53     2   54    2   45    2   27    2
                0.035        213
paramyosin [Sarcoptes scabiei] 30 0.035    1        293    1   381   1   425   1   203   1
                 3.8
C subunit of V-ATPase         26           2
                                          24 3.8    289    1   377   1   421   1   199   1
                0.12
putative secreted histamine  105           1        140    1   175   1   189   1   94    1
               1E-084        104
ribosomal protein S15 [Ixodes pacificus]1 303 1e-084139    1   174   1   188   1   93    1
               2E-057           1
60S ribosomal protein L37 [Ixodes pac306             2    63   173   1   186   1   92    1
                 2.9
alpha-2-macroglobulin [Ixod  102           1        137    1   170   1   183   1   90    1
               7E-085         21
ribosomal protein L21 [Ornithodoros m 2             135    1   167   1   178   1   88    1
                             100           1        134    1   166   1   177   1   87    1
                 1.4
putative secreted protein [ 98             1        131    1   160   1   168   1   85    1
                0.92          97
cytochrome c [Ixodes pacificus]            1
                                           25 0.92 130     1   159   1   167   1   84    1
                 7.2          95
putative secreted salivary gland pept 1             128    1   157   1   165   1   82    1
                 8.1
truncated secreted metallop94              1        126    1   155   1   163   1   80    1
               5E-082         93
40S ribosomal protein S11 [Dermacento1              125    1   154   1   162   1   79    1
                 4.7          92
unknown protein [Ixodes scapularis]        1 22 4.7 124    1   153   1   161   1   78    1
                0.34          91
unnamed protein product [Ixodes rici 1              123    1   152   1   160   1   77    1
               2E-083         90
ribosomal protein S14 [Ixodes pacificus]1 299 2e-083122    1   151   1   159   1   76    1
                 4.0          24
RNA polymerase II largest subunit [pa 2             34     2   35    2   158   1   21    2
               3E-064         88
60S ribosomal protein L35-like protei 1             120    1   149   1   156   1   75    1
                 histamine rel
IgE-dependent 0.98            87           1        119    1   148   1   155   1   74    1
                 4.9          86
elongation factor-1 alpha [Dinothrombi 1            118    1   147   1   154   1   73    1
                 6.8          84
proteasome alpha subunit [Ornithodoro 1             116    1   145   1   152   1   72    1
                0.86          82
alpha-2-macroglobulin precursor splic 1             114    1   143   1   148   1   70    1
                 8.2         205
heat shock protein 82 [Steganacarus m 1             274    1   350   1   386   1   193   1
                 2.0         195
serine proteinase 1 [Tyrophagus putre 1             259    1   334   1   367   1   181   1
               1E-118        183
40S ribosomal protein S5 [Ixodes paci 1             246    1   320   1   353   1   167   1
               2E-004           1
putative HMG-like protein [Dermacento     306        4    12   304   1   337   1   152   1
                0.43          68
putative secreted salivary gland pept 1             93     1   111   1   113   1   61    1
                0.19          67
putative HMG-like protein [Dermacento 1             92     1   110   1   111   1   60    1
               4E-061         66                    91
ribosomal protein L44 [Ixodes pacificus] 1 224 4e-061      1   108   1   109   1   59    1
               1E-084         63
ribosomal protein S18 [Ixodes ricinus] 1303 1e-084  86     1   98    1   99    1   56    1
                 9.6
putative 18.7 kDa secreted 57              1        79     1   87    1   85    1   48    1
                0.95
cytochrome Bc1 complex chai   51           1        72     1   80    1   78    1   42    1
                0.56          50
proteasome-like protein [Rhipicephalu 1             71     1   79    1   77    1   41    1
               4E-071         49
40S ribosomal protein S12 [Dermacento1              69     1   77    1   75    1   40    1
                 4.4
BM86-like protein [Hyalomma   48           1        68     1   76    1   74    1   39    1
                 4.2
putative cytochrome oxidase1subunit 306             15     3   72    1   69    1   36    1
                 8.1         227
group 3 allergen SMIPP-S Yv6018H06 [S      1        310    1   400   1   448   1   216   1
                0.008        211
block of proliferation protein [Ixode      1        290    1   378   1   422   1   200   1
                 1.5         233
hypothetical protein [Ixodes ricinus]      1
                                           25 1.5 316      1   406   1   454   1   222   1
                 1.5         233
hypothetical protein [Ixodes ricinus]      1
                                           25 1.5 316      1   406   1   454   1   222   1
sodium channel4.8            103
                  protein [Varroa destru 1          138    1   172   1   185   1   91    1
                 7.0          83
KOG1656-like protein [Ornithodoros mo1              115    1   144   1   150   1   71    1
               4E-069         80
40S ribosomal protein S30 [Ixodes pac 1             112    1   141   1   146   1    8    3
               7E-010         79
ribosomal protein L41 [Ixodes pacificus] 1 54 7e-010111    1   140   1   145   1    0    1
                0.11
calreticulin precursor [Boo 133           1          179   1     226   1   242   1   123   1
                 1.5
9.8 kDa basic protein [Ambl 127           1          171   1     217   1   232   1   117   1

                           192           1       256        1    331   1   364   1   178   1
                6.7        46
allergen Blo t Mag 1 [Blomia tropicalis] 122 6.7 66         1    73    1   71    1   37    1
                protein     1
40S ribosomal0.002 S30 [Ixodes pac306             2        63    385   1   430   1    8    3
                           89            1       121        1    150   1   157   1    8    3

                 0.90         204
gelsolin-like allergen Der f 16 [Derm     1       271       1    346   1   379   1   26    2
                  1.2         203
group 2 allergen [Tyrophagus putresce 1           269       1    344   1   377   1   26    2
                  2.9
putative secreted histamine14             3       35        2    38    2   29    2   10    3
               3E-006         130
fed tick salivary protein 3 [Ixodes s     1       174       1    221   1   236   1   11    3
                  5.4
putative secreted histamine14             3       35        2    38    2   29    2   10    3
                 0.49          14
group 3 allergen SMIPP-S Yv9017F05 [S     3       146       1    183   1   198   1   10    3
                  2.9         224
NADH dehydrogenase subunit 4 [Ixodes1             306       1    396   1   444   1   213   1
                 0.11           1
cytochrome c oxidase subunit 1 [Strat 306         245       1    319   1   352   1   356   1
                  [Boophilus 113
5'-nucleotidase 5.6           microplus] 1 22 5.6 150       1    187   1   202   1   100   1
                  1.1
C subunit of V-ATPase           9         4
                                         24 1.1   250       1    325   1   358   1   172   1
                 0.77          54
cytochrome oxidase subunit III [Ambl 1            76        1    84    1   82    1   45    1
               shock-related226
putative heat 6E-056           protein [  1       309       1    399   1   447   1   29    2
                  2.8         134
putative secreted salivary gland pept 1           180       1    227   1   243   1   124   1
                  2.0         112
antigen B membrane protein [Boophilus 1           148       1    185   1   200   1   98    1
               2E-014           1
fed tick salivary protein 3 [Ixodes s    306       1       105   19    3   14    3   11    3
                  0.0         242
putative secreted salivary gland pept 1           326       1    418   1   466   1   228   1
               4E-097         240
fed tick salivary protein 5 [Ixodes s     1       324       1    415   1   463   1   29    2
               9E-059           1
fed tick salivary protein 3 [Ixodes s    306       1       105   19    3   14    3   11    3
                  0.0
putative serine protease wi 252           1       351       1    451   1   503   1   14    3

                 5.3     188            1
NADH dehydrogenase 5 [Carios capensis] 23 5.3    252       1     327   1   360   1   174   1
                0.16
paramyosin allergen [Blomia4tropicalis] 6 27 0.1646        2     49    2   41    2   13    3
               0.054                             46
paramyosin allergen [Blomia4tropicalis] 6 29 0.054         2     49    2   41    2   13    3
                0.24     146
NADH dehydrogenase 5 [Ixodes hexagonus] 1        197
                                               26 0.24     1     251   1   271   1   135   1
                0.67     220
paramyosin [Boophilus micro             1        302       1     391   1   437   1   13    3
                          81            1        113       1     142   1   147   1   69    1
                 4.8     137
cytochrome oxidase 1 [Haemaphysalis 1            186       1     235   1   252   1   128   1
                 4.5     129
calreticulin [Amblyomma americanum] 1            173
                                            23 4.5         1     220   1   235   1   119   1
               0.011     206            1
GTP-binding protein RAN [Ixodes ricinus] 32 0.011275       1     351   1   387   1   194   1

GP80 precursor1.0           microplus] 1
                 [Boophilus182                       244
                                                25 1.0     1     318   1   351   1   165   1
               5.4         101
IgE-binding protein C-terminal fragment 1            136   1     168   1   181   1   89    1

                0.68          147
unnamed protein product [Ixodes rici 1            198      1     252   1   273   1   136   1
                 2.1           44
esterase [Tetranychus cinnabarinus]       1 22 2.1 61      1     65    1   60    1   33    1
sodium channel3.1               1
                  protein [Varroa destru 306       74      1     82    1   80    1   44    1
                 1 [Boophilus
chitin synthase0.11            47         1        67      1     75    1   73    1   38    1
                 1.8            1
heat shock protein 82 [Steganacarus m    306      149      1     186   1   201   1   99    1
               1E-131         238
fed tick salivary protein 8 [Ixodes s     1       321      1     412   1   460   1   224   1

              0.25        173
proteasome-like protein [Rhipicephalu 1              234   1     308   1   341   1   156   1
               2.6        125
alpha-2-macroglobulin precursor splic 1              168   1     214   1   229   1   114   1

                 5.4          101
IgE-binding protein C-terminal fragment 1            136   1     168   1   181   1   89    1
               1E-055          19
putative salivary secreted peptide [I      2         28    2     88    1   86    1   77    1
                 2.3          197
HDM allergen [Dermatophagoides pteron      1         262   1     337   1   370   1   184   1
                0.38          189
retinoid X receptor [Amblyomma america     1         253   1     328   1   361   1   175   1
               1E-137         185
cytochrome oxidase 3 [Ixodes persulc 1               248   1     322   1   355   1   169   1
               1E-008         178
fed tick salivary protein 9 [Ixodes s      1         239   1     313   1   346   1   12    3
                 2.0
putative secreted histamine 1   binding p 306        44    2     47    2   292   1   142   1
                 7.7          153
paramyosin [Sarcoptes scabiei] 22 7.7      1         205   1     263   1   288   1   139   1
                              142          1         193   1     245   1   265   1   132   1
               4E-062          65
NADH dehydrogenase 6 [Ixodes persulc1                88    1     102   1   103   1   58    1
               4E-079           64
ATP synthase c-subunit [Ixodes pacifi 1            87    1     99    1   100   1   57    1
               1E-110           62
ATPase subunit 6 [Ixodes persulcatus] 1 389 e-110  85    1     97    1   98    1   55    1
               1E-105           61
cytochrome oxidase 2 [Ixodes persulc 1             84    1     94    1   95    1   54    1
                  0.0           60
cytochrome oxidase subunit 1 [Ixodes 1             83    1     93    1   94    1   53    1
                protein
9.8 kDa basic1E-035 [Ambl59                1       82    1     91    1   91    1   52    1
                [Ixodes
cytochrome c2E-062 pacificus]    1        228      80
                                          306 2e-062     1     89    1   89    1   50    1
                                52         1       73    1     81    1   79    1   43    1
                0.088          231
paramyosin allergen [Blomia tropicalis] 1 29 0.088 314   1     404   1   452   1   220   1
                  2.0          230         1
NADH dehydrogenase 4 [Carios capensis] 23 2.0      313   1     403   1   451   1   219   1
                  9.7          229
elongation factor 1 alpha [Prodinychu 1            312   1     402   1   450   1   218   1
                  1.0
autoantigen [Rhipicephalus221   appendicula1       303   1     392   1   439   1   210   1
                               225         1       307   1     397   1   445   1   214   1
                  2.8          222
heat shock protein 82 [Steganacarus m 1            304   1     394   1   442   1   211   1
                  4.2
paramyosin allergen [Blomia1tropicalis]30623 4.2 300     1     389   1   434   1   208   1
                  3.7          216
cytochrome b [Ixodes holocyclus]           1
                                           22 3.7 296    1     384   1   428   1   205   1
                  2.7
trypsin [Blomia tropicalis] 212        22 1 2.7    292   1     380   1   424   1   202   1
                  4.4
BM86-like protein [Hyalomma     32         2       291   1     379   1   423   1   201   1
                  2.0
activated STAT-1/3 inhibito140             1       191   1     243   1   263   1   131   1
                0.014           31
fed tick salivary protein 9 [Ixodes s      2       184   1     232   1   249   1   12    3
                  9.6           28
serine proteinase inhibitor serpin-1       2       37    2     218   1   233   1   118   1
                  6.3          109
cytochrome oxidase subunit III [Ambl 1             144   1     180   1   195   1   95    1
                   protein 9 [Ixodes s
fed tick salivary 0.0          237         1       320   1     411   1   459   1   12    3
                  0.0
putative secreted NADH-ubiq    251         1       350   1     450   1   501   1   237   1
               7E-011
macrophage migration inhibi    163         1       221   1     289   1   317   1   148   1
                  0.0          243
putative secreted salivary gland pept 1            327   1     419   1   467   1   229   1

                           69           1         94     1     112   1   114   1   62    1

              7E-074         1
unnamed protein product [Ixodes rici 306          32      2    113   1   116   1   18    2
                0.0          1
salivary gland protein [Ixodes scapul 306         345     1    441   1   490   1   18    2
              1E-064         1
putative secreted salivary gland pept 306          1     105   427   1   476   1   234   1

             1E-013        143
myosin regulatory light chain [Ixodes   1         194    1     247   1   267   1   133   1
             1E-072
IgE-dependent histamine rel132          1         178    1     225   1   241   1   122   1
           Number
               of
          matches
             to is-
          all_blastx
            _is-all-
View Psi- match- Antisense
  Blast     maker    ?


                1
ISUFJ-cluster-253       1E-148

                15
IS-6-12-J-cluster-114 6E-41
ISUFL75          7    7E-71
ISUFL127         2    5E-67
ISUFL126         2    3E-75
ISUFL105         2    3E-38
ISNU-L-ISNU-352  3    1E-59
ISNU-L-ISNU-305  3    2E-28
ISNU-L-ISN-83 3       4E-79
ISNU-L-ISN-1463       1E-105
ISN-L111         5    2E-57
is-all-489       5    2E-45
is-all-465       2    7E-74
                 3
IS-6-12-J-cluster-361 5E-47
IS-6-12L-454 2        8E-17
        158      1      81                          1
                                       1 IS-6-12L-315   7E-48
gi|55736017|gb|AAV63535.1|
IS-18-24-clu397 2     2E-51
                 7    3E-83
gi|55736027|gb|AAV63540.1|

               4      1E-100
gi|55736029|gb|AAV63541.1|

ISUFL68         6       1E-156
ISUFL133        7       1E-129
ISNU-L-ISN-96   5       8E-49
ISN-L-169       2       5E-94
is-all-clu546   5       1E-88

                 1
IS-6-12-J-cluster-439   1E-07

                 8
IS-6-12-J-cluster-407   1E-115

                1
ISUFJ-cluster-325     1E-41
ISN-L-209       4     5E-60
                1    1E-109
gi|22164280|gb|AAM93645.1|AF483723_1

               8      3E-62
gi|51011530|gb|AAT92174.1|
ISUFL92        3      1E-106
ISUFL81        7      1E-92
ISUFL76        4      9E-37
ISUFL72         5     4E-51
ISUFL56        11     3E-93
ISUFL49         7     6E-67
ISUFL48        11     1E-119
ISUFL46        17     9E-59
               21     1E-153
gi|51011534|gb|AAT92176.1|
ISUFL26        19     1E-134
ISUFL22        18     1E-169
ISUFL21        19     1E-153
ISUFL129        5     3E-42
ISUFL114        7     2E-76
ISUFL109        9     1E-79
is-all-clu554   4     1E-107
is-all-538      4     2E-32
is-all-456      6     1E-124
is-all-441      7     1E-73
is-all-416      5     3E-63
is-all-399      9     1E-145
is-all-398
is-all-397      9     1E-100
is-all-378      9     1E-156
IS-6-12L-99    14     1E-110
                7     4E-85
gi|51011510|gb|AAT92164.1|
               12     2E-58
gi|51011502|gb|AAT92160.1|
IS-6-12L-68    10     3E-72
IS-6-12L-52    11     2E-95
IS-6-12L-50    14     2E-48
IS-6-12L-37     8     5E-66
IS-6-12L-35    13     2E-83
IS-6-12L-32    18     1E-77
IS-6-12L-311 4        7E-65
IS-6-12L-30    18     1E-89
IS-6-12L-293 4        1E-55
IS-6-12L-29    11     2E-84
               13     8E-84
gi|51011526|gb|AAT92172.1|
IS-6-12L-260 4        1E-62
IS-6-12L-242 5        9E-65
IS-6-12L-223 11       2E-82
IS-6-12L-22    16     1E-122
IS-6-12L-136 8        1E-105
IS-6-12L-109 5        1E-108
IS-18-24-clu110 6     1E-26
ISUFL78         5     4E-99
               10     1E-118
gi|51011494|gb|AAT92156.1|
ISUFL107        4     1E-86
ISN-L-99       14     3E-90
ISN-L-89       11     1E-57
               19     3E-61
gi|51011508|gb|AAT92163.1|
ISN-L-49       24     7E-86
ISN-L-180       5     9E-68
ISN-L-141       9     3E-81
ISN-L-140       6     1E-102
ISN-L-128      10     4E-73
ISN-L-126       9     4E-46
ISN-L-101       6     5E-68
is-all-clu550   4     2E-48
is-all-382     15        0
is-all-360     19     1E-157
is-all-360
IS-6-12L-87     5     1E-33
IS-6-12L-111 13       1E-108
               10     3E-74
gi|51011536|gb|AAT92177.1|
               13     3E-10
                 1
IS-6-12-J-cluster-577   7E-67
                 2
IS-6-12-J-cluster-444   6E-62

ISUFL74         3       1E-134
ISN-L-109       9       1E-90
is-all-426     19       1E-90
IS-6-12L-25    16       2E-70

ISUFJ-cluster-3926    1E-157
ISUFJ-cluster-3658    1E-128
is-all-450       2    1E-105
                 5
IS-6-12-J-cluster-51  4E-70
                 4
IS-6-12-J-cluster-235 1E-125
                 5
IS-6-12-J-cluster-143 1E-117
is-all-553       4    2E-56
         376     1     166           1 ISUFL301 1   2E-96
                 8
IS-6-12-J-cluster-190 5E-94
ISUFL522         3    2E-71
ISN-L-168        4    2E-63
is-all-clu549    6    1E-100
                 3
IS-6-12-J-cluster-578 1E-139
                 2
IS-6-12-J-cluster-170 8E-82
IS-18-24-clu117 5     9E-75
                 3    1E-128
gi|56159969|gb|AAV80796.1|
gi|55736025|gb|AAV63539.1|
                 2    9E-59
gi|55736021|gb|AAV63537.1|
                 4    4E-52
gi|22164292|gb|AAM93651.1|AF483729_1

ISUFL65          5      1E-108
ISNU-L-ISNU-953         4E-90
ISNU-L-ISNU-941         9E-90
ISNU-L-ISN-1573         1E-56
is-all-429       6      1E-96
IS-6-12L-106 5          2E-96
                 7
IS-6-12-J-cluster-84    1E-96
                 6
IS-6-12-J-cluster-461   6E-97
IS-18-24-clu11411       1E-103

ISUFL293        4       7E-90
IS-6-12L-589    3       1E-83

ISNU-L-ISN-1679       3E-27
ISN-L369         5    3E-39
ISN-L-157        6    9E-56
ISN-L-112        7    5E-66
                 3
IS-6-12-J-cluster-183 5E-73
gi|55736031|gb|AAV63542.1|

ISUFL125         2      1E-104
                 4
IS-6-12-J-cluster-432   4E-94

IS-6-12L-589 3          1E-83
        70     1          49        1 ISN-L-197 9   2E-57
ISUFL97        3        1E-163
ISUFL67        9        1E-113
ISUFL47       58        1E-133
ISUFL14       27        1E-170
              11
ISNU-L-ISNU-313         3E-47
ISNU-L-ISN-86 8         1E-101
ISNU-L-ISN-1035         2E-29
ISN-L-61      17        6E-64
ISN-L-51        34    6E-80
ISN-L-41        26    4E-70
ISN-L-23        96    1E-101
ISN-L-22       117       0
ISN-L-216        7    1E-46
                16    7E-63
gi|51011608|gb|AAT92213.1|
ISN-L-155        9    3E-25
is-all-clu620    3    1E-153
IS-all-clu578    4    1E-64
is-all-clu571    4    3E-90
is-all-611       3    3E-52
is-all-564       4    7E-46
is-all-507       5    1E-105
is-all-484       5    3E-89
is-all-413       7    4E-50
is-all-395       8    6E-43
is-all-393       8    1E-71
                19
IS-6-12-J-IS612-63    1E-138
ISUFL14          3    7E-63
                 3
IS-6-12-J-cluster-451 2E-54
                 6
IS-6-12-J-cluster-132 9E-52
gi|55736033|gb|AAV63543.1|
                 2    1E-141
gi|22164298|gb|AAM93654.1|AF483732_1
ISNU-cluster-364 2    6E-59
                 2    2E-89
gi|56159967|gb|AAV80795.1|

ISJ-ISPL-P2-F6 2        8E-81

ISJ-ISPL-P4-E5 1      5E-86
               20     1E-109
gi|50363178|gb|AAT75325.1|
                3     6E-65
gi|56159947|gb|AAV80785.1|

ISNU-L-ISN-1458         6E-82
                 4
IS-6-12-J-cluster-559   7E-98

				
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