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					MSDS #8074 COVER SHEET

EHIL16AM
Component # 1857343 1857849 1857871 1857886 1857761 1856558 1857133 1856960 1857473

Human IL-16AM ELISA
Description Pre-Coated Plate Stop Solution TMB Substrate Solution 30X Wash Buffer EHIL16 Lyophilized Standard EHIL16 Antibody EHIL16 Concentrate Standard Diluent SA-HRP Dilution Buffer

Pierce 3747 N. Meridian Road

PO BOX 117 Rockford, IlL 61105

(815) 968-0747 (815) 968-7316 fax

www.thermo.com

Material Safety Data Sheet
Pre-Coated Plates

Pre-Coated Plates

1.

Product and company identification
1861096 1861145 1861148 1861150 1861152LT 1861155 1861157 1861159 1861163 1861166 1861170 1861172 1861174 1861176 1861178 1861180 1861182 1861184 1861186 1861188 1861193 1861312 1861314 1861341 1861343 1861345 1861347 1861349 1861351 NCI1200 NCI1510 NCI1514 NCI1517 NCI1520 NCI1521 NCI1541 NCI1550 NCI1560 NCI1561 NCI1562 NCI1563 NCI1564 NCI1565 NCI1566 NCI1568 NCI1569 NCI5123 NCI5127 NCI5138 NCI5140 NCI5141 NCI5142 NCI5143 NCI5152 NCI5155 NCI5158 NCI5159 NCI5146 NCI5147 NCI5149 NCI5151 NCI5153 NCI5164 NCI5502 NCI5511 NCI8706 NCI8710 NCI9658

1.

Product and company identification
: Pre-Coated Plates : Thermo Fisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 or 800.874.3723 Manufacturer : Thermo Fisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 800.874.3723

Product name Supplier

Product No.

: 15031 15031B 15041 15042 15100 15102 15108 15109 15110 15112 15115 15116 15117 15118 15119 15120 15121 15122 15123 15124 15125 15126 15127 15128 15129 15130 15131 15132 15133 15134 15135 15136 15137 15138 15140 15141 15142 15143 15145 15146 15147 15148 15150 15151 15152 15153 15154 15155 15156 15157 15182 15184 15186 15190 15216 15217 15218 15219 15234 15240 15242 15334 15340 15342 15400 15401 15402 15405 15406 15407 15442 15500 15501 15502 15503 15504 15505 15506 15507 15508 15509 15510 15511 15512 15513 15600 15601 15602 15603 15605 15606 15607 15610 15611 15612 15613 15615 15616 15617 15618 15620 15100B 15116B 15119B 15120B 15124B 15127B 15128B 15129B 15130B 15131B 15135B 15140B 15142B 15147B 15150B 15151B 15182B 15240B 15242B 15340B 15342B 15401B 15402B 15407B 15500B 15501B 15502B 15503B 15504B 15505B 15506B 15507B 15509B 15511B 15512B 15603B 15608B 15613B 15618B 1824670 1857209 1857224 1857227 1857230 1857233 1857236 1857242 1857245 1857248 1857251 1857254 1857260 1857263 1857266 1857270 1857273 1857276 1857279 1857284 1857287 1857290 1857293 1857296 1857303 1857306 1857309 1857314 1857316 1857322 1857331 1857334 1857337 1857343 1857346 1857349 1857352 1857355 1857369 1857373 1857376 1857379 1857382 1857385 1857388 1857900 1857902 1857906 1857907 1857910 1857914 1858179 1858227 1858256 1858267 1858451 1858514 1858520 1858614 1858628 1858649 1858664 1858673 1858678 1858679 1858685 1858688 1858699 1858802 1858825 1858828 1858829 1858830 1858831 1858832 1858833 1858849 1858849LT 1858889 1858891 1858912 1858921 1858930 1858937 1858948 1858950 1858952 1858954 1858959 1858967 1858978 1858981 1859143 1859145 1859150 1859159 1859161 1859194 1859199 1859203 1859216 1859234LT 1859235 1859240 1859243 1859280 1859282 1859284LT 1859286 1859291 1859293 1859397 1859420 1859449 1859494 1859496 1859527 1859528 1859531 1859537 1859538 1859566 1859568 1859570 1859576 1859578 1859580 1859585 1859671 1859704 1859710 1859748 1859750 1859755 1859757 1859759 1859761 1859764 1859774 1859776 1859784 1859785 1859794 1859796 1859798 1859800 1859802 1859804 1859806 1859808 1859878 1859897 1859902 1859906 1859910 1859932 1859933 1859934 1859935 1859949 1859951 1859981 1859983 1859985 1859987 1859989 1859991 1860006 1860008 1860010 1860019 1860021 1860023 1860025 1860036 1860045 1860054 1860057 1860059 1860061 1860063 1860065 1860072 1860074 1860076 1860078 1860120 1860122 1860124 1860126 1860133 1860135 1860139 1860140 1860146 1860148 1860162 1860164 1860166 1860182 1860184 1860186 1860188 1860190 1860192 1860196 1860203 1860206 1860276 1860378 1860380 1860381 1860382 1860384 1860392 1860395 1860399 1860401 1860413 1860415 1860417 1860426 1860430 1860440 1860442 1860450 1860452 1860456 1860460 1860465 1860471 1860637 1860639 1860643 1860645 1860649 1860655 1860657 1860659 1860661 1860663 1860664 1860667 1860690 1860691 1860693 1860695 1860701 1860703 1860705 1860708 1860710 1860712 1860714 1860717 1860726 1860728 1860742 1860744 1860774 1860776 1860780 1860782 1860784 1860786 1860788 1860790 1860793 1860795 1860800 1860802 1860804 1860806 1860808 1860810 1860812 1860814 1860816 1860818 1860820 1860822 1860824 1860826 1860828 1860830 1860832 1860833 1860834 1860836 1860841 1860998 1861000 1861006 1861015 1861017 1861019 1861022 1861024 1861029 1861031 1861034 1861036 1861038 1861040 1861042 1861044 1861046 1861050 1861052 1861054 1861056 1861058 1861060 1861062 1861069 1861071 1861073 1861075 1861077 1861079 1861082 1861084 1861086 1861088 1861090 1861092 1/7

MSDS # Validation date Print date Responsible name In case of emergency

: : : : :

2432 5/28/2008. 5/28/2008. MSDS (Regulatory Affairs) CHEMTREC: Use of 800.424.9300 Substance/Preparation OUTSIDE US: 202.483.7616

Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.

2.

Hazards identification
: Solid. : While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product. : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. No known significant effects or critical hazards. Avoid prolonged contact with eyes, skin and clothing.

Physical state OSHA/HCS status

Emergency overview

Potential acute health effects Inhalation : No known significant effects or critical hazards. Ingestion : No known significant effects or critical hazards. Skin : No known significant effects or critical hazards. Eyes : No known significant effects or critical hazards. Potential chronic health effects Chronic effects : No known significant effects or critical hazards. Carcinogenicity : No known significant effects or critical hazards. Mutagenicity : No known significant effects or critical hazards. Teratogenicity : No known significant effects or critical hazards. Developmental effects : No known significant effects or critical hazards. Fertility effects : No known significant effects or critical hazards. Over-exposure signs/symptoms Inhalation : No specific data. Ingestion : No specific data. Skin : No specific data. Eyes : No specific data. : None known. Medical conditions aggravated by overexposure 5/28/2008. 2/7

5/28/2008.

Pre-Coated Plates

Pre-Coated Plates

2.

Hazards identification

6.

Accidental release measures
: No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). : Move containers from spill area. Approach release from upwind. Prevent entry into sewers, water courses, basements or confined areas. Vacuum or sweep up material and place in a designated, labeled waste container. Dispose of via a licensed waste disposal contractor. Note: see section 1 for emergency contact information and section 13 for waste disposal. : Move containers from spill area. Vacuum or sweep up material and place in a designated, labeled waste container. Dispose of via a licensed waste disposal contractor.

Personal precautions The substance is not classified as dangerous according to Directive 67/548/EEC and its amendments. Classification : Not classified. See toxicological information (section 11)

3.

Composition/information on ingredients

Environmental precautions

Substance/preparation : Substance There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section.

Large spill

4.

First aid measures
: Move exposed person to fresh air. Keep person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. Get medical attention if symptoms occur. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. : Wash out mouth with water. Remove dentures if any. Move exposed person to fresh air. Keep person warm and at rest. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Get medical attention if symptoms occur. Never give anything by mouth to an unconscious person. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.

Small spill

Inhalation

7.

Handling and storage
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous. Do not reuse container. : Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

Handling

Ingestion

Storage

: Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur. Wash clothing before reuse. Clean shoes thoroughly before reuse. Eye contact : Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs. Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training. See section 11 for more detailed information on health effects and symptoms. Skin contact

8.

Exposure controls/personal protection

Europe No exposure limit value known. Consult local authorities for acceptable exposure limits. Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace atmosphere or biological monitoring may be required to determine the effectiveness of the ventilation procedures or other control measures and/or the necessity to use respiratory protective equipment. Engineering measures : No special ventilation requirements. Good general ventilation should be sufficient to control worker exposure to airborne contaminants. If this product contains ingredients with exposure limits, use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure below any recommended or statutory limits. Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location. : Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator. 4/7

5.

Fire-fighting measures
: No specific fire or explosion hazard. : Use an extinguishing agent suitable for the surrounding fire. : None known. : Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. : No specific data. : Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Flammability of the product Extinguishing media Suitable Not suitable Special exposure hazards

Hazardous combustion products Special protective equipment for fire-fighters

Personal protection Respiratory

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Pre-Coated Plates

Pre-Coated Plates

8.

Exposure controls/personal protection
: Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. : Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts. : Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product. : Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

12 . Ecological information
Environmental effects United States Aquatic ecotoxicity Conclusion/Summary Other adverse effects : No known significant effects or critical hazards.

Hands

Eyes

: Not available. : No known significant effects or critical hazards.

Skin

13 . Disposal considerations
Waste disposal : The generation of waste should be avoided or minimized wherever possible. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers.

Environmental exposure controls

9.

Physical and chemical properties
: Solid.

Physical state

10 . Stability and reactivity
Chemical stability Conditions to avoid Incompatible materials Hazardous decomposition products Possibility of hazardous reactions : The product is stable. Under normal conditions of storage and use, hazardous polymerization will not occur. : No specific data. : No specific data. : Under normal conditions of storage and use, hazardous decomposition products should not be produced. : Will not occur.

: Within the present knowledge of the supplier, this product is not regarded as hazardous waste, as defined by EU Directive 91/689/EEC. Disposal should be in accordance with applicable regional, national and local laws and regulations. Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION for additional handling information and protection of employees. Hazardous waste

14 . Transport information
Regulatory information DOT Classification IATA-DGR Class PG* : Packing group UN number Not regulated. Proper shipping name Classes Not available. PG* -

Not available. Not available.

11 . Toxicological information
United States Acute toxicity Conclusion/Summary Chronic toxicity Conclusion/Summary Carcinogenicity Conclusion/Summary Mutagenicity Conclusion/Summary Teratogenicity Conclusion/Summary Reproductive toxicity Conclusion/Summary Europe Chronic effects Carcinogenicity Mutagenicity Teratogenicity Developmental effects Fertility effects 5/28/2008. : : : : : : No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. 5/7 : Not available. : Not available. : Not available. : Not available. : Not available. : Not available.

15 . Regulatory information
United States HCS Classification U.S. Federal regulations : Not regulated. : United States inventory (TSCA 8b): Not determined. SARA 302/304/311/312 extremely hazardous substances: No products were found. SARA 302/304 emergency planning and notification: No products were found. SARA 302/304/311/312 hazardous chemicals: No products were found. SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found. Clean Water Act (CWA) 307: No products were found. Clean Water Act (CWA) 311: No products were found. Clean Air Act (CAA) 112 accidental release prevention: No products were found. Clean Air Act (CAA) 112 regulated flammable substances: No products were found. Clean Air Act (CAA) 112 regulated toxic substances: No products were found. Canada WHMIS (Canada) : Not controlled under WHMIS (Canada).

5/28/2008.

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Pre-Coated Plates

15 . Regulatory information
Canadian lists : CEPA Toxic substances: This material is not listed. Canadian ARET: This material is not listed. Canadian NPRI: This material is not listed. Alberta Designated Substances: This material is not listed. Ontario Designated Substances: This material is not listed. Quebec Designated Substances: This material is not listed. : Canada inventory: Not determined. : This product is not classified according to EU legislation. : Product No. : Australia inventory (AICS): Not determined. China inventory (IECSC): Not determined. Korea inventory (KECI): Not determined. Philippines inventory (PICCS): Not determined. Japan inventory (ENCS): Not determined.

Material Safety Data Sheet
Stop Solution

1.

Product and company identification
: Stop Solution : Thermo Fisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 or 800.874.3723 Manufacturer : Thermo Fisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 800.874.3723

Product name Supplier

Canada inventory EU regulations Risk phrases International regulations International lists

16 . Other information
Label requirements Hazardous Material Information System (U.S.A.) : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. : Health Flammability Physical hazards 0 0 0

MSDS # Validation date Print date Responsible name In case of emergency

: 1857849 1857850 1857851 1857852 1857855 1857856 1857861 1857862 1857864 1859353 1861409 1900445 N600 : 5452 : 2/21/2008. : 2/21/2008. : MSDS (Regulatory Affairs) : CHEMTREC: Use of 800.424.9300 Substance/Preparation Refer to the instruction booklet for OUTSIDE US: proper and intended use. 202.483.7616 Otherwise, contact supplier for specific applications.

2.

Hazards identification
: Liquid. [Clear sparkling liquid.] : Odorless. : This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). : CANCER HAZARD - CONTAINS MATERIAL WHICH CAN CAUSE CANCER. Avoid exposure - obtain special instructions before use. Do not breathe vapor or mist. Contains material which can cause cancer. Risk of cancer depends on duration and level of exposure.

Physical state Odor OSHA/HCS status Emergency overview

The customer is responsible for determining the PPE code for this material. : National Fire Protection Association (U.S.A.) 0 Health 0 0 Flammability Instability Special : 5/28/2008. : 5/28/2008. Date of issue Date of previous issue : 5/7/2008. Version : 3.03 Indicates information that has changed from previously issued version. Notice to reader To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.

Date of printing

Routes of entry : Eye contact. Inhalation. Ingestion. Potential acute health effects Inhalation : No known significant effects or critical hazards. Ingestion : No known significant effects or critical hazards. Skin : No known significant effects or critical hazards. Eyes : No known significant effects or critical hazards. Potential chronic health effects Chronic effects : No known significant effects or critical hazards. Carcinogenicity : Contains material which can cause cancer. Risk of cancer depends on duration and level of exposure. Mutagenicity : No known significant effects or critical hazards. Teratogenicity : No known significant effects or critical hazards. Developmental effects : No known significant effects or critical hazards. Fertility effects : No known significant effects or critical hazards. Over-exposure signs/symptoms Inhalation : No specific data. Ingestion : No specific data. 2/21/2008. 1/8

5/28/2008.

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Stop Solution

Stop Solution

2.

Hazards identification
: No specific data. : No specific data. : None known.

5.

Fire-fighting measures
: In a fire or if heated, a pressure increase will occur and the container may burst. : Use an extinguishing agent suitable for the surrounding fire. : None known. : Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. : No specific data. : Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Skin Eyes Medical conditions aggravated by overexposure

Flammability of the product Extinguishing media Suitable Not suitable Special exposure hazards

The preparation is not classified as dangerous according to Directive 1999/45/EC and its amendments. Classification : Not classified. See toxicological information (section 11)

3.

Composition/information on ingredients
CAS number 7664-93-9 % 0.1 - 1

Hazardous combustion products Special protective equipment for fire-fighters

United States Name Sulfuric acid

6.

Accidental release measures
: No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). : Stop leak if without risk. Move containers from spill area. Approach release from upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash spillages into an effluent treatment plant or proceed as follows. Contain and collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or diatomaceous earth and place in container for disposal according to local regulations (see section 13). Dispose of via a licensed waste disposal contractor. Contaminated absorbent material may pose the same hazard as the spilled product. Note: see section 1 for emergency contact information and section 13 for waste disposal. : Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water-soluble or absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor.

Personal precautions

Substance/preparation : Preparation There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section.

Environmental precautions

4.

First aid measures
: Get medical attention immediately. Move exposed person to fresh air. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or selfcontained breathing apparatus. Keep person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. It may be dangerous to the person providing aid to give mouth-tomouth resuscitation. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. : Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs. : Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Wash contaminated clothing thoroughly with water before removing or wear gloves. Continue to rinse for at least 10 minutes. Get medical attention. Wash clothing before reuse. Clean shoes thoroughly before reuse. : Get medical attention immediately. Wash out mouth with water. Remove dentures if any. Move exposed person to fresh air. Keep person warm and at rest. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Never give anything by mouth to an unconscious person. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. : No action shall be taken involving any personal risk or without suitable training. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or self-contained breathing apparatus. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation. Wash contaminated clothing thoroughly with water before removing or wear gloves. Large spill

Inhalation

Eye contact

Small spill

Skin contact

7.

Handling and storage
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Do not get in eyes or on skin or clothing. Do not breathe vapor or mist. Do not ingest. If during normal use the material presents a respiratory hazard, use only with adequate ventilation or wear appropriate respirator. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous. Do not reuse container. : Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

Handling

Ingestion

Storage

Protection of first-aiders

See section 11 for more detailed information on health effects and symptoms.

2/21/2008.

2/8

2/21/2008.

3/8

Stop Solution

Stop Solution

8.

Exposure controls/personal protection
Exposure limits ACGIH (United States, 0/2000). STEL: 3 mg/m³ TWA: 1 mg/m³ NIOSH (United States, 0/2003). TWA: 1 mg/m³ OSHA (United States, 0/1989). TWA: 1 mg/m³ ACGIH TLV (United States, 1/2007). TWA: 0.2 mg/m³ 8 hour(s). NIOSH REL (United States, 12/2001). TWA: 1 mg/m³ 10 hour(s). OSHA PEL (United States, 11/2006). TWA: 1 mg/m³ 8 hour(s). OSHA PEL 1989 (United States, 3/1989). TWA: 1 mg/m³ 8 hour(s).

9.

Physical and chemical properties
: : : : Liquid. [Clear sparkling liquid.] Colorless. Odorless. Easily soluble in the following materials: cold water and hot water.

Product name United States sulphuric acid

Physical state Color Odor Solubility

10 . Stability and reactivity
Chemical stability Conditions to avoid Incompatible materials Hazardous decomposition products Possibility of hazardous reactions : The product is stable. Under normal conditions of storage and use, hazardous polymerization will not occur. : Avoid exposure - obtain special instructions before use. : No specific data. : Under normal conditions of storage and use, hazardous decomposition products should not be produced. : Will not occur.

Europe No exposure limit value known. Consult local authorities for acceptable exposure limits. Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace atmosphere or biological monitoring may be required to determine the effectiveness of the ventilation procedures or other control measures and/or the necessity to use respiratory protective equipment. Engineering measures : If user operations generate dust, fumes, gas, vapor or mist, use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure to airborne contaminants below any recommended or statutory limits. Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location. Personal protection Respiratory : Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator. : Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. : Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts. : Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product. : Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

11 . Toxicological information
United States Acute toxicity Product/ingredient name sulphuric acid Conclusion/Summary Chronic toxicity Conclusion/Summary Carcinogenicity Conclusion/Summary Classification Product/ingredient name sulphuric acid Mutagenicity Conclusion/Summary Teratogenicity Conclusion/Summary Reproductive toxicity Europe Conclusion/Summary Chronic effects Carcinogenicity Mutagenicity Teratogenicity Developmental effects Fertility effects Result LD50 Oral : Not available. : Not available. : Not available. ACGIH A2 : Not available. : Not available. IARC 1 EPA NIOSH None. NTP Proven. OSHA Species Rat Dose 350 mg/kg Exposure -

Hands

Eyes

Skin

: Not available. : No known significant effects or critical hazards. : No known significant effects or critical hazards. : No known significant effects or critical hazards. : No known significant effects or critical hazards. : No known significant effects or critical hazards. : No known significant effects or critical hazards.

Environmental exposure controls

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Stop Solution

12 . Ecological information
Environmental effects United States Aquatic ecotoxicity Not available. Conclusion/Summary Other adverse effects : No known significant effects or critical hazards.

15 . Regulatory information
SARA 313 notifications must not be detached from the MSDS and any copying and redistribution of the MSDS shall include copying and redistribution of the notice attached to copies of the MSDS subsequently redistributed. California Prop. 65 WARNING: This product contains a chemical known to the State of California to cause cancer. Maximum Ingredient name Cancer Reproductive No significant risk acceptable dosage level level sulphuric acid Yes. No. No. No.

: Not available. : No known significant effects or critical hazards.

13 . Disposal considerations
Waste disposal : The generation of waste should be avoided or minimized wherever possible. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers.

Canada WHMIS (Canada) Canadian lists

: Within the present knowledge of the supplier, this product is not regarded as hazardous waste, as defined by EU Directive 91/689/EEC. Disposal should be in accordance with applicable regional, national and local laws and regulations. Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION for additional handling information and protection of employees. Hazardous waste

: Not controlled under WHMIS (Canada). : CEPA Toxic substances: None of the components are listed. Canadian ARET: None of the components are listed. Canadian NPRI: None of the components are listed. Alberta Designated Substances: None of the components are listed. Ontario Designated Substances: None of the components are listed. Quebec Designated Substances: None of the components are listed. : Canada inventory: All components are listed or exempted. : This product is not classified according to EU legislation. : : Australia inventory (AICS): All components are listed or exempted. China inventory (IECSC): All components are listed or exempted. Korea inventory (KECI): All components are listed or exempted. Philippines inventory (PICCS): All components are listed or exempted. Japan inventory (ENCS): All components are listed or exempted.

14 . Transport information
Regulatory information DOT Classification IATA-DGR Class PG* : Packing group UN number Not regulated. Proper shipping name Classes Not available. PG* -

Canada inventory EU regulations Risk phrases International regulations International lists

Not available. Not available.

15 . Regulatory information
United States HCS Classification U.S. Federal regulations : Carcinogen : United States inventory (TSCA 8b): All components are listed or exempted. SARA 302/304/311/312 extremely hazardous substances: No products were found. SARA 302/304 emergency planning and notification: No products were found. SARA 302/304/311/312 hazardous chemicals: No products were found. SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found. Clean Water Act (CWA) 307: No products were found. Clean Water Act (CWA) 311: sulphuric acid Clean Air Act (CAA) 112 accidental release prevention: No products were found. Clean Air Act (CAA) 112 regulated flammable substances: No products were found. Clean Air Act (CAA) 112 regulated toxic substances: No products were found. SARA 313 Form R - Reporting requirements Supplier notification 2/21/2008. Product name : sulphuric acid : sulphuric acid CAS number 7664-93-9 7664-93-9 Concentration 0.1 - 1 0.1 - 1 6/8

16 . Other information
Label requirements Hazardous Material Information System (U.S.A.) : CANCER HAZARD - CONTAINS MATERIAL WHICH CAN CAUSE CANCER. : Health Flammability Physical hazards 2 0 0

The customer is responsible for determining the PPE code for this material. : National Fire Protection Association (U.S.A.) 0 Health 1 0 Flammability Instability Special Date of printing Date of issue Date of previous issue 2/21/2008. : 2/21/2008. : 2/21/2008. : 2/14/2008. 7/8

Stop Solution

16 . Other information
Version : 1.01 Indicates information that has changed from previously issued version. Notice to reader To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR. This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.

Material Safety Data Sheet
TMB Substrate Solution

1.

Product and company identification
: TMB Substrate Solution : ThermoFisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 or 800.874.3723 : : : : : : Manufacturer : ThermoFisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 800.874.3723

Product name Supplier

Product No. MSDS # Validation date Print date Responsible name In case of emergency

0034028 0034028B 1857867 1857870 1857871 1857872 1859173 1859350 1901712 5454 2/8/2008. 2/8/2008. MSDS (Regulatory Affairs) CHEMTREC: Use of : Refer to the instruction booklet for proper and intended use. 800.424.9300 Substance/Preparation Otherwise, contact supplier for OUTSIDE US: specific applications. 202.483.7616

2.

Hazards identification
: Liquid. [Clear sparkling liquid.] : Odorless. : While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product. : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. No known significant effects or critical hazards. Avoid prolonged contact with eyes, skin and clothing. : Eye contact. Inhalation. Ingestion.

Physical state Odor OSHA/HCS status

Emergency overview

Routes of entry Potential acute health effects Inhalation : No known significant effects or critical hazards. : No known significant effects or critical hazards. Ingestion : No known significant effects or critical hazards. Skin : No known significant effects or critical hazards. Eyes Potential chronic health effects Chronic effects : No known significant effects or critical hazards. Carcinogenicity : No known significant effects or critical hazards. Mutagenicity : No known significant effects or critical hazards. Teratogenicity : No known significant effects or critical hazards. Developmental effects : No known significant effects or critical hazards. Fertility effects : No known significant effects or critical hazards. Over-exposure signs/symptoms Inhalation : No specific data. Ingestion : No specific data. Skin : No specific data. 2/21/2008. 8/8 2/8/2008.

1/7

TMB Substrate Solution

TMB Substrate Solution

2.

Hazards identification
: No specific data. : None known.

6.

Accidental release measures
: No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). : Stop leak if without risk. Move containers from spill area. Approach release from upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash spillages into an effluent treatment plant or proceed as follows. Contain and collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or diatomaceous earth and place in container for disposal according to local regulations (see section 13). Dispose of via a licensed waste disposal contractor. Contaminated absorbent material may pose the same hazard as the spilled product. Note: see section 1 for emergency contact information and section 13 for waste disposal. : Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water-soluble or absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor.

Eyes Medical conditions aggravated by overexposure

Personal precautions

The preparation is not classified as dangerous according to Directive 1999/45/EC and its amendments. Classification : Not classified. See toxicological information (section 11)

Environmental precautions

3.

Composition/information on ingredients

Large spill

Substance/preparation : Preparation There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section.

4.

First aid measures
: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs. : Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur. Wash clothing before reuse. Clean shoes thoroughly before reuse. : Move exposed person to fresh air. Keep person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. Get medical attention if symptoms occur. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. : Wash out mouth with water. Remove dentures if any. Move exposed person to fresh air. Keep person warm and at rest. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Get medical attention if symptoms occur. Never give anything by mouth to an unconscious person. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.

Small spill

Eye contact

Skin contact

7.

Handling and storage
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous. Do not reuse container. : Store between the following temperatures: 2 to 8°C (35.6 to 46.4°F). Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

Handling

Inhalation

Ingestion

Storage

8.

Exposure controls/personal protection

Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training. See section 11 for more detailed information on health effects and symptoms.

Europe No exposure limit value known. Consult local authorities for acceptable exposure limits. Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace atmosphere or biological monitoring may be required to determine the effectiveness of the ventilation procedures or other control measures and/or the necessity to use respiratory protective equipment. Engineering measures : No special ventilation requirements. Good general ventilation should be sufficient to control worker exposure to airborne contaminants. If this product contains ingredients with exposure limits, use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure below any recommended or statutory limits. Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location.

5.

Fire-fighting measures
: In a fire or if heated, a pressure increase will occur and the container may burst. : Use an extinguishing agent suitable for the surrounding fire. : None known. : Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. : No specific data. : Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Flammability of the product Extinguishing media Suitable Not suitable Special exposure hazards

Hazardous combustion products Special protective equipment for fire-fighters

Personal protection 2/8/2008. 2/7 2/8/2008. 3/7

TMB Substrate Solution

TMB Substrate Solution

8.

Exposure controls/personal protection
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator. : Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. : Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts. : Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product. : Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

11 . Toxicological information
Europe Conclusion/Summary Chronic effects Carcinogenicity Mutagenicity Teratogenicity Developmental effects Fertility effects : Not available. : No known significant effects or critical hazards. : No known significant effects or critical hazards. : No known significant effects or critical hazards. : No known significant effects or critical hazards. : No known significant effects or critical hazards. : No known significant effects or critical hazards.

Respiratory

Hands

Eyes

Skin

12 . Ecological information
Environmental effects United States Aquatic ecotoxicity Conclusion/Summary Other adverse effects : No known significant effects or critical hazards.

Environmental exposure controls

9.

Physical and chemical properties
: : : : : : Liquid. [Clear sparkling liquid.] Colorless to light yellow. Odorless. 3.35 to 3.75 1.01 Easily soluble in the following materials: cold water and hot water.

: Not available. : No known significant effects or critical hazards.

Physical state Color Odor pH Relative density Solubility

13 . Disposal considerations
Waste disposal : The generation of waste should be avoided or minimized wherever possible. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers.

10 . Stability and reactivity
Stability Conditions to avoid Materials to avoid Hazardous decomposition products Hazardous polymerization : The product is stable. Under normal conditions of storage and use, hazardous polymerization will not occur. : No specific data. : No specific data. : Under normal conditions of storage and use, hazardous decomposition products should not be produced. : Will not occur.

: Within the present knowledge of the supplier, this product is not regarded as hazardous waste, as defined by EU Directive 91/689/EEC. Disposal should be in accordance with applicable regional, national and local laws and regulations. Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION for additional handling information and protection of employees. Hazardous waste

14 . Transport information
Regulatory information DOT Classification IATA-DGR Class UN number Proper shipping name Classes Not available. Not available. PG* -

11 . Toxicological information
United States Acute toxicity Conclusion/Summary Chronic toxicity Conclusion/Summary Carcinogenicity Conclusion/Summary Mutagenicity Conclusion/Summary Teratogenicity Conclusion/Summary Reproductive toxicity 2/8/2008. : Not available. : Not available. : Not available. : Not available. : Not available.

Not available. Not available. Not available. Not available.

PG* : Packing group

15 . Regulatory information
United States HCS Classification U.S. Federal regulations : Not regulated. : United States inventory (TSCA 8b): All components are listed or exempted. SARA 302/304/311/312 extremely hazardous substances: No products were found. SARA 302/304 emergency planning and notification: No products were found. SARA 302/304/311/312 hazardous chemicals: No products were found. SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found. 5/7

4/7

2/8/2008.

TMB Substrate Solution

TMB Substrate Solution

15 . Regulatory information
Clean Water Act (CWA) 307: No products were found. Clean Water Act (CWA) 311: No products were found. Clean Air Act (CAA) 112 accidental release prevention: No products were found. Clean Air Act (CAA) 112 regulated flammable substances: No products were found. Clean Air Act (CAA) 112 regulated toxic substances: No products were found. United States inventory (TSCA 8b) Canada WHMIS (Canada) Canadian lists : United States inventory (TSCA 8b): All components are listed or exempted.

16 . Other information
Indicates information that has changed from previously issued version. Notice to reader To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.

: Not controlled under WHMIS (Canada). : CEPA Toxic substances: None of the components are listed. Canadian ARET: None of the components are listed. Canadian NPRI: None of the components are listed. Alberta Designated Substances: None of the components are listed. Ontario Designated Substances: None of the components are listed. Quebec Designated Substances: None of the components are listed. : Canada inventory: All components are listed or exempted. : This product is not classified according to EU legislation. : : Australia inventory (AICS): All components are listed or exempted. China inventory (IECSC): All components are listed or exempted. Korea inventory (KECI): Not determined. Philippines inventory (PICCS): Not determined. Japan inventory (ENCS): Not determined.

Canada inventory EU regulations Risk phrases International regulations International lists

16 . Other information
Label requirements Hazardous Material Information System (U.S.A.) : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. : Health Flammability Physical hazards 0 0 0

The customer is responsible for determining the PPE code for this material. : National Fire Protection Association (U.S.A.) 0 Health 0 0 Flammability Instability Special Date of printing Date of issue Date of previous issue Version 2/8/2008. : : : : 2/8/2008. 2/8/2008. No previous validation. 1 6/7 2/8/2008. 7/7

Material Safety Data Sheet
30X Wash Buffer

30X Wash Buffer

2.

Hazards identification

1.

Product and company identification
: 30X Wash Buffer : Thermo Fisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 or 800.874.3723 : : : : : : Manufacturer : Thermo Fisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 800.874.3723

Product name Supplier

Product No. MSDS # Validation date Print date Responsible name In case of emergency

1857886 1857887 1857892 1857893 1857894 1901681 5456 2/27/2008. 2/27/2008. MSDS (Regulatory Affairs) CHEMTREC: Use of 800.424.9300 Substance/Preparation Refer to the instruction booklet for OUTSIDE US: proper and intended use. 202.483.7616 Otherwise, contact supplier for specific applications.

Over-exposure signs/symptoms Inhalation : Adverse symptoms may include the following: respiratory tract irritation coughing Ingestion : No specific data. Skin : Adverse symptoms may include the following: irritation redness Eyes : Adverse symptoms may include the following: pain or irritation watering redness Medical conditions aggravated by overexposure : Pre-existing disorders involving any target organs mentioned in this MSDS as being at risk may be aggravated by over-exposure to this product.

The preparation is not classified as dangerous according to Directive 1999/45/EC and its amendments. Classification : Not classified. See toxicological information (section 11)

3.

Composition/information on ingredients
CAS number 7647-14-5 77-86-1 % 10 - 20 3-5

2.

Hazards identification
: Liquid. [Clear to slightly hazy liquid.] : This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). : WARNING ! CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. CONTAINS MATERIAL THAT CAN CAUSE TARGET ORGAN DAMAGE. Irritating to eyes, respiratory system and skin. Avoid exposure - obtain special instructions before use. Do not breathe vapor or mist. Avoid contact with eyes, skin and clothing. Contains material that can cause target organ damage. Use only with adequate ventilation. Keep container tightly closed and sealed until ready for use. Wash thoroughly after handling.

Physical state OSHA/HCS status Emergency overview

United States Name Sodium Chloride Tris (Tris(hydroxymethyl)aminomethane)

Substance/preparation : Preparation There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section.

4.

First aid measures
: Move exposed person to fresh air. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or self-contained breathing apparatus. Keep person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation. Get medical attention. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours. : Wash out mouth with water. Remove dentures if any. Move exposed person to fresh air. Keep person warm and at rest. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Get medical attention. Never give anything by mouth to an unconscious person. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. : Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Continue to rinse for at least 10 minutes. Get medical attention. Wash clothing before reuse. Clean shoes thoroughly before reuse. 2/8

Inhalation

: Eye contact. Inhalation. Ingestion. Routes of entry Potential acute health effects Inhalation : Irritating to respiratory system. Exposure to decomposition products may cause a health hazard. Serious effects may be delayed following exposure. : No known significant effects or critical hazards. Ingestion : Irritating to skin. Skin : Irritating to eyes. Eyes Potential chronic health effects Chronic effects : Contains material that can cause target organ damage. Carcinogenicity : No known significant effects or critical hazards. Mutagenicity : No known significant effects or critical hazards. Teratogenicity : No known significant effects or critical hazards. Developmental effects : No known significant effects or critical hazards. Fertility effects : No known significant effects or critical hazards. Target organs : Contains material which causes damage to the following organs: kidneys, liver, skin, eyes, stomach. 2/27/2008. 1/8

Ingestion

Skin contact

2/27/2008.

30X Wash Buffer

30X Wash Buffer

4.

First aid measures
: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention. : No action shall be taken involving any personal risk or without suitable training. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or self-contained breathing apparatus. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation.

7.

Handling and storage
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Do not get in eyes or on skin or clothing. Do not breathe vapor or mist. Do not ingest. Use only with adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous. Do not reuse container. : Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

Eye contact

Handling

Protection of first-aiders

See section 11 for more detailed information on health effects and symptoms.

5.

Fire-fighting measures
: In a fire or if heated, a pressure increase will occur and the container may burst. : Use an extinguishing agent suitable for the surrounding fire. : None known. : Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. : Decomposition products may include the following materials: carbon oxides nitrogen oxides halogenated compounds metal oxide/oxides : Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Storage

Flammability of the product Extinguishing media Suitable Not suitable Special exposure hazards

8.

Exposure controls/personal protection

Europe No exposure limit value known. Consult local authorities for acceptable exposure limits. Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace atmosphere or biological monitoring may be required to determine the effectiveness of the ventilation procedures or other control measures and/or the necessity to use respiratory protective equipment. Engineering measures : Use only with adequate ventilation. If user operations generate dust, fumes, gas, vapor or mist, use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure to airborne contaminants below any recommended or statutory limits. Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location. : Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator. : Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. : Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts. : Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product. : Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

Hazardous combustion products

Special protective equipment for fire-fighters

6.

Accidental release measures
: No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). : Stop leak if without risk. Move containers from spill area. Approach release from upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash spillages into an effluent treatment plant or proceed as follows. Contain and collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or diatomaceous earth and place in container for disposal according to local regulations (see section 13). Dispose of via a licensed waste disposal contractor. Contaminated absorbent material may pose the same hazard as the spilled product. Note: see section 1 for emergency contact information and section 13 for waste disposal. : Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water-soluble or absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor.

Personal precautions

Environmental precautions

Personal protection Respiratory

Large spill

Hands

Eyes

Small spill

Skin

Environmental exposure controls

2/27/2008.

3/8

2/27/2008.

4/8

30X Wash Buffer

30X Wash Buffer

9.

Physical and chemical properties
: Liquid. [Clear to slightly hazy liquid.] : 7.8 to 8 : Easily soluble in the following materials: cold water and hot water.

11 . Toxicological information
Teratogenicity Developmental effects Fertility effects : No known significant effects or critical hazards. : No known significant effects or critical hazards. : No known significant effects or critical hazards.

Physical state pH Solubility

10 . Stability and reactivity
Chemical stability Conditions to avoid Incompatible materials Hazardous decomposition products : The product is stable. Under normal conditions of storage and use, hazardous polymerization will not occur. : No specific data. : No specific data. : Under normal conditions of storage and use, hazardous decomposition products should not be produced.

12 . Ecological information
Environmental effects United States Aquatic ecotoxicity Conclusion/Summary Other adverse effects : No known significant effects or critical hazards.

: Not available. : No known significant effects or critical hazards.

13 . Disposal considerations
Waste disposal

11 . Toxicological information
United States Acute toxicity Product/ingredient name sodium chloride Result LD50 Dermal LD50 Intraperitoneal LD50 Oral LDLo Intraperitoneal LDLo Subcutaneous LD50 Intravenous LD50 Oral : Not available. : Not available. : Not available. ACGIH IARC EPA NIOSH None. None. NTP OSHA None. None. Species Rabbit Rat Rat Rat Rat Rat Rat Dose >10 g/kg 2600 mg/kg 3000 mg/kg 3.72 g/kg 3500 mg/kg 1800 mg/kg 5900 mg/kg Exposure -

: The generation of waste should be avoided or minimized wherever possible. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers.

: Within the present knowledge of the supplier, this product is not regarded as hazardous waste, as defined by EU Directive 91/689/EEC. Disposal should be in accordance with applicable regional, national and local laws and regulations. Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION for additional handling information and protection of employees. Hazardous waste

14 . Transport information
Regulatory information DOT Classification IATA-DGR Class PG* : Packing group UN number Proper shipping name Classes Not available. Not available. PG* -

1,3-propanediol, 2-amino-2(hydroxymethyl)Conclusion/Summary Chronic toxicity Conclusion/Summary Carcinogenicity Conclusion/Summary Classification Product/ingredient name sodium chloride 1,3-propanediol, 2-amino-2(hydroxymethyl)Mutagenicity Conclusion/Summary Teratogenicity Conclusion/Summary Reproductive toxicity Conclusion/Summary Europe Chronic effects Carcinogenicity Mutagenicity 2/27/2008.

Not available. Not available. Not available. Not available.

15 . Regulatory information
United States HCS Classification U.S. Federal regulations : Irritating material Target organ effects : United States inventory (TSCA 8b): All components are listed or exempted. SARA 302/304/311/312 extremely hazardous substances: No products were found. SARA 302/304 emergency planning and notification: No products were found. SARA 302/304/311/312 hazardous chemicals: sodium chloride SARA 311/312 MSDS distribution - chemical inventory - hazard identification: sodium chloride: Immediate (acute) health hazard, Delayed (chronic) health hazard Clean Water Act (CWA) 307: No products were found. Clean Water Act (CWA) 311: No products were found. Clean Air Act (CAA) 112 accidental release prevention: No products were found. Clean Air Act (CAA) 112 regulated flammable substances: No products were found. Clean Air Act (CAA) 112 regulated toxic substances: No products were found. 5/8 2/27/2008. 6/8

: Not available. : Not available. : Not available.

: No known significant effects or critical hazards. : No known significant effects or critical hazards. : No known significant effects or critical hazards.

30X Wash Buffer

30X Wash Buffer

15 . Regulatory information
Canada WHMIS (Canada) Canadian lists : Class D-2B: Material causing other toxic effects (Toxic). : CEPA Toxic substances: None of the components are listed. Canadian ARET: None of the components are listed. Canadian NPRI: None of the components are listed. Alberta Designated Substances: None of the components are listed. Ontario Designated Substances: None of the components are listed. Quebec Designated Substances: None of the components are listed. : Canada inventory: All components are listed or exempted. : This product is not classified according to EU legislation. : : Australia inventory (AICS): All components are listed or exempted. China inventory (IECSC): All components are listed or exempted. Korea inventory (KECI): All components are listed or exempted. Philippines inventory (PICCS): All components are listed or exempted. Japan inventory (ENCS): All components are listed or exempted.

16 . Other information
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.

Canada inventory EU regulations Risk phrases International regulations International lists

16 . Other information
Label requirements Hazardous Material Information System (U.S.A.) : CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. CONTAINS MATERIAL THAT CAN CAUSE TARGET ORGAN DAMAGE. : Health Flammability Physical hazards 2 0 0

The customer is responsible for determining the PPE code for this material. : National Fire Protection Association (U.S.A.) 0 Health 2 0 Flammability Instability Special : 2/27/2008. : 2/27/2008. Date of issue : 2/22/2008. Date of previous issue : 1.01 Version Indicates information that has changed from previously issued version. Notice to reader To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist. Date of printing 2/27/2008. 7/8 2/27/2008. 8/8

Material Safety Data Sheet
Endogen Standard

Endogen Standard

2.

Hazards identification
: : : : : : No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. Contains material which does not cause damage to the following organs: central nervous system (CNS).

1.

Product and company identification
: Endogen Standard : Thermo Fisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 or 800.874.3723 Manufacturer : Thermo Fisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 800.874.3723

Product name Supplier

Carcinogenicity Mutagenicity Teratogenicity Developmental effects Fertility effects Target organs

Over-exposure signs/symptoms Inhalation : Adverse symptoms may include the following: respiratory tract irritation coughing : No specific data. : No specific data. : Adverse symptoms may include the following: irritation redness : None known.

Product No.

: 1857616 1857619 1857620 1857622 1857631 1857632 1857634 1857639 1857640 1857646 1857649 1857652 1857655 1857658 1857661 1857664 1857667 1857669 1857671 1857673 1857675 1857677 1857679 1857683 1857686 1857688 1857689 1857692 1857695 1857698 1857701 1857712 1857715 1857718 1857721 1857727 1857730 1857731 1857733 1857737 1857740 1857741 1857743 1857746 1857749 1857752 1857755 1857756 1857761 1857762 1857767 1857770 1857773 1857784 1857812 1857818 1857821 1857824 1857827 1858180 1858186 1859623 1859626 1859629 1859632 1859635 1859641 1859656 1859954 1861270 1861273 1861290 1861298 1901057 : : : : : 6834 6/10/2008. 6/10/2008. MSDS (Regulatory Affairs) CHEMTREC: Use of 800.424.9300 Substance/Preparation OUTSIDE US: 202.483.7616

Ingestion Skin Eyes

MSDS # Validation date Print date Responsible name In case of emergency

Medical conditions aggravated by overexposure

: Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.

The preparation is not classified as dangerous according to Directive 1999/45/EC and its amendments. Classification : Not classified. See toxicological information (section 11)

3.

Composition/information on ingredients

2.

Hazards identification
: Solid. [Powder.] : Odorless. : While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product. : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. No known significant effects or critical hazards. Handling and/or processing of this material may generate a dust which can cause mechanical irritation of the eyes, skin, nose and throat. Avoid prolonged contact with eyes, skin and clothing. : Eye contact. Inhalation. Ingestion.

Physical state Odor OSHA/HCS status

Substance/preparation : Preparation There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section.

4.

First aid measures
: Move exposed person to fresh air. Keep person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. Get medical attention if symptoms occur. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. : Wash out mouth with water. Remove dentures if any. Move exposed person to fresh air. Keep person warm and at rest. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Get medical attention if symptoms occur. Never give anything by mouth to an unconscious person. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. : Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur. Wash clothing before reuse. Clean shoes thoroughly before reuse. : Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs. 2/7

Inhalation

Emergency overview

Ingestion

Routes of entry Potential acute health effects Inhalation : Exposure to airborne concentrations above statutory or recommended exposure limits may cause irritation of the nose, throat and lungs. : No known significant effects or critical hazards. Ingestion : No known significant effects or critical hazards. Skin : Exposure to airborne concentrations above statutory or recommended exposure limits Eyes may cause irritation of the eyes. Potential chronic health effects Chronic effects : No known significant effects or critical hazards. 6/10/2008.

Skin contact

Eye contact

1/7

6/10/2008.

Endogen Standard

Endogen Standard

4.

First aid measures

8.

Exposure controls/personal protection

Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training. See section 11 for more detailed information on health effects and symptoms.

Europe No exposure limit value known. Consult local authorities for acceptable exposure limits. Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace atmosphere or biological monitoring may be required to determine the effectiveness of the ventilation procedures or other control measures and/or the necessity to use respiratory protective equipment. Engineering measures : Use only with adequate ventilation. If user operations generate dust, fumes, gas, vapor or mist, use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure to airborne contaminants below any recommended or statutory limits. Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location. : Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator. : Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. : Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts. If operating conditions cause high dust concentrations to be produced, use dust goggles. : Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product. : Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

5.

Fire-fighting measures
: No specific fire or explosion hazard. : Use an extinguishing agent suitable for the surrounding fire. : None known. : Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. : No specific data. : Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Flammability of the product Extinguishing media Suitable Not suitable Special exposure hazards

Hazardous combustion products Special protective equipment for fire-fighters

6.

Accidental release measures
: No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Avoid breathing dust. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). : Move containers from spill area. Approach release from upwind. Prevent entry into sewers, water courses, basements or confined areas. Vacuum or sweep up material and place in a designated, labeled waste container. Avoid creating dusty conditions and prevent wind dispersal. Dispose of via a licensed waste disposal contractor. Note: see section 1 for emergency contact information and section 13 for waste disposal. : Move containers from spill area. Vacuum or sweep up material and place in a designated, labeled waste container. Dispose of via a licensed waste disposal contractor.

Personal protection Respiratory

Personal precautions

Hands

Environmental precautions

Eyes

Large spill

Skin

Small spill

Environmental exposure controls

7.

Handling and storage
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing dust. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous. Do not reuse container. : Do not store above the following temperature: -20°C (-4°F). Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

9.

Physical and chemical properties
: Solid. [Powder.] : White. : Odorless.

Handling

Physical state Color Odor

10 . Stability and reactivity
Chemical stability Conditions to avoid Incompatible materials Hazardous decomposition products Possibility of hazardous reactions : The product is stable. Under normal conditions of storage and use, hazardous polymerization will not occur. : No specific data. : No specific data. : Under normal conditions of storage and use, hazardous decomposition products should not be produced. : Will not occur.

Storage

6/10/2008.

3/7

6/10/2008.

4/7

Endogen Standard

Endogen Standard

11 . Toxicological information
United States Acute toxicity Conclusion/Summary Chronic toxicity Conclusion/Summary Carcinogenicity Conclusion/Summary Mutagenicity Conclusion/Summary Teratogenicity Conclusion/Summary Reproductive toxicity Conclusion/Summary Europe Chronic effects Carcinogenicity Mutagenicity Teratogenicity Developmental effects Fertility effects : : : : : : Repeated or prolonged inhalation of dust may lead to chronic respiratory irritation. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. : Not available. : Not available. : Not available. : Not available. : Not available. : Not available.

14 . Transport information
Regulatory information DOT Classification IATA-DGR Class PG* : Packing group UN number Proper shipping name Classes Not available. Not available. PG* -

Not available. Not available. Not available. Not available.

15 . Regulatory information
United States HCS Classification U.S. Federal regulations : Not regulated. : United States inventory (TSCA 8b): All components are listed or exempted. SARA 302/304/311/312 extremely hazardous substances: No products were found. SARA 302/304 emergency planning and notification: No products were found. SARA 302/304/311/312 hazardous chemicals: No products were found. SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found. Clean Water Act (CWA) 307: No products were found. Clean Water Act (CWA) 311: sodium phosphate, dibasic Clean Air Act (CAA) 112 accidental release prevention: No products were found. Clean Air Act (CAA) 112 regulated flammable substances: No products were found. Clean Air Act (CAA) 112 regulated toxic substances: No products were found. Canada WHMIS (Canada) Canadian lists : Not controlled under WHMIS (Canada). : CEPA Toxic substances: None of the components are listed. Canadian ARET: None of the components are listed. Canadian NPRI: None of the components are listed. Alberta Designated Substances: None of the components are listed. Ontario Designated Substances: None of the components are listed. Quebec Designated Substances: None of the components are listed. : Canada inventory: Not determined. : This product is not classified according to EU legislation. : : Australia inventory (AICS): All components are listed or exempted. China inventory (IECSC): All components are listed or exempted. Korea inventory (KECI): All components are listed or exempted. Philippines inventory (PICCS): All components are listed or exempted. Japan inventory (ENCS): Not determined.

12 . Ecological information
Environmental effects United States Aquatic ecotoxicity Conclusion/Summary Other adverse effects : No known significant effects or critical hazards.

: Not available. : No known significant effects or critical hazards. Canada inventory EU regulations Risk phrases International regulations International lists

13 . Disposal considerations
Waste disposal : The generation of waste should be avoided or minimized wherever possible. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers.

: Within the present knowledge of the supplier, this product is not regarded as hazardous waste, as defined by EU Directive 91/689/EEC. Disposal should be in accordance with applicable regional, national and local laws and regulations. Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION for additional handling information and protection of employees. Hazardous waste

16 . Other information
Label requirements Hazardous Material Information System (U.S.A.) : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. : Health Flammability 0 0 6/7

6/10/2008.

5/7

6/10/2008.

Endogen Standard

SAFETY DATA SHEET
Physical hazards 0
Conforms to 91/155/EEC and ISO 11014-1 United States English

16 . Other information
1.
The customer is responsible for determining the PPE code for this material. National Fire Protection Association (U.S.A.) : 0 Health 0 0 Flammability Instability Special Date of printing : 6/10/2008. : 6/10/2008. Date of issue Date of previous issue : 3/17/2008. Version : 1.02 Indicates information that has changed from previously issued version. Notice to reader To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.

Identification of the substance/preparation and of the company/undertaking
:

Product name

Biotinylated Antibody Reagent; part of 'IL-16, Human, Biotrak Assay'
RPN2772

Catalogue Number

:

Article Number

:

90RPN2772 9525190004-2

:

Supplier

:

Amersham Biosciences SE-751 84 Uppsala Sweden
Supplier US Canada 800-526-3593 800-526-3593 Information Contact ChemTrec (US) ChemTrec (US) 1-800-424-9300 1-703-527-3887

Emergency telephone number

:

2.
Name

Composition / information on ingredients
CAS # % by Weight Exposure Limits

No hazardous ingredient.

3.

Hazards identification
: Liquid. : CAUTION! MAY BE HARMFUL IF SWALLOWED.
Do not ingest. Wash thoroughly after handling.

Physical State and Appearance Emergency Overview

Routes of Entry Potential Chronic Health Effects

: Not available. : CARCINOGENIC EFFECTS: Classified None. by NIOSH [Sodium azide]. Classified A4 (Not classifiable for human or animal.) by ACGIH [Sodium azide]. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available. : Not available.

Overexposure /Signs/Symptoms

See Toxicological Information (section 11)

Date of issue

: 25 February 2003

Continued on Next Page

Page: 1/4

6/10/2008.

7/7

Biotinylated Antibody Reagent; part of 'IL-16, Human, Biotrak Assay'

RPN2772

Biotinylated Antibody Reagent; part of 'IL-16, Human, Biotrak Assay'
Ionicity (in Water)

RPN2772

: Not available. : See solubility in water. : Not available.

4. 5.

First-aid measures Fire-fighting measures
: Not applicable.

Dispersion Properties Physical Chemical Comments

10. Stability and reactivity
Stability

Extinguishing Media Suitable Flammability of the Product Autoignition Temperature Flash Points Flammable Limits Fire Hazards in Presence of Various Substances Explosion Hazards in Presence of Various Substances Special Remarks on Fire Hazards

: The product is stable.

: Non-flammable. : Not applicable. : Not applicable. : Not applicable. : Not applicable. : Not considered as a product presenting risks of explosion. : Not available.

Hazardous Decomposition Products Hazardous Polymerization

: Not available. : Will not occur.

11. Toxicological information
: CARCINOGENIC EFFECTS: Classified None. by NIOSH [Sodium azide]. Classified A4 (Not classifiable for human or animal.) by ACGIH [Sodium azide]. Other Toxic Effects on : Slightly hazardous in case of skin contact (irritant, sensitizer), of eye contact (irritant), of ingestion, of inhalation (lung irritant). Humans Special Remarks on Toxicity to : Not available. Animals Special Remarks on Chronic : Not available. Effects on Humans
Chronic Effects on Humans Special Remarks on Other Toxic Effects on Humans

6.

Accidental release measures
: Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. : Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.

: Not available.

Environmental Precautions and Clean-up Methods Small Spill and Leak

12. Ecological information
BOD and COD Biodegradable/OECD Mobility Products of Degradation Toxicity of the Products of Biodegradation Special Remarks on the Products of Biodegradation

7.
Storage

Handling and storage
: Do not ingest. Wash thoroughly after handling.
: Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above -20°C (-4°F).

: Not available. : Not available. : Not available. : Not available. : The products of degradation are less toxic than the product itself. : Not available.

Handling

8.

Exposure controls/personal protection

13. Disposal considerations
Personal protective equipment Feet Protective Clothing (Pictograms)

: Not applicable. :

Methods of disposal ; Waste of residues ; Contaminated packaging Waste Stream

: Waste must be disposed of in accordance with federal, state and local environmental control regulations.

: Not available.

Consult your local or regional authorities.

Personal Protection in Case of a Large Spill

: Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.

14. Transport information
International transport regulations Regulatory Information ADR/RID Class UN number Proper shipping name Class Packing Group Label Additional information

No hazardous ingredients.
Consult local authorities for acceptable exposure limits.

9.
Color Odor Taste

Physical and chemical properties
: Liquid. : Colorless. : Not available.

Not regulated. Not regulated. Not regulated. Not regulated. Not regulated.

-

-

-

Physical state

IMDG Class

-

-

-

: Not available. : Not applicable. : Not applicable.
: Not available.

TDG Classification

-

-

Molecular Weight Molecular Formula pH Critical Temperature Volatility VOC Specific Gravity Solubility

DOT Classification

-

-

-

: Not available. : Not available. : Not available. : Not available.
: Easily soluble in cold water, hot water.
IATA-DGR Class

-

-

-

Date of issue

: 25 February 2003

Continued on Next Page

Page: 2/4

Date of issue

: 25 February 2003

Continued on Next Page

Page: 3/4

Biotinylated Antibody Reagent; part of 'IL-16, Human, Biotrak Assay'

RPN2772

15. Regulatory information
HCS Classification U.S. Federal Regulations

SAFETY STATEMENT
This document is only available in English.

: Not controlled under the HCS (United States). : TSCA 8(b) inventory: Sodium azide TSCA 8(d) H and S data reporting: Sodium azide SARA 302/304/311/312 extremely hazardous substances: Sodium azide SARA 302/304 emergency planning and notification: Sodium azide SARA 302/304/311/312 hazardous chemicals: Sodium azide SARA 311/312 MSDS distribution - chemical inventory - hazard identification: Sodium azide: Immediate (Acute) Health Hazard
Clean Water Act (CWA) 307: No products were found. Clean Water Act (CWA) 311: No products were found. Clean air act (CAA) 112 accidental release prevention: No products were found. Clean air act (CAA) 112 regulated flammable substances: No products were found. Clean air act (CAA) 112 regulated toxic substances: No products were found.

1. Identification of the substance/preparation and of the company/undertaking
Product name
:

Streptavidin-HRP Concentrate; part of 'MIP-1a, Human, Biotrak™ Assay' RPN2773

Catalogue Number

:

Article Number

:

90RPN2773 9525190003-4

Component Number Supplier

: :

RPN2773CJ Amersham Biosciences SE-751 84 Uppsala Sweden
Europe USA

State Regulations

: Pennsylvania RTK: Sodium azide: (environmental hazard, generic environmental hazard) Florida: Sodium azide Minnesota: Sodium azide Massachusetts RTK: Sodium azide New Jersey: Sodium azide California prop. 65: No products were found. : Not available. : R22- Harmful if swallowed. : Australia (NICNAS): Sodium azide
China: Sodium azide Germany water class: Sodium azide Japan (MITI): Sodium azide Korea (TCCL): Sodium azide Philippines (RA6969): Sodium azide

International Regulations EINECS DSCL (EEC) International Lists

Emergency telephone number

:

+46 18 612 0000 1-800-424-9300

2. Composition / information on ingredients
Substance/Preparation
: Preparation
To the present knowledge of the supplier, this product does not contain any hazardous ingredients in quantities requiring reporting in this section, in accordance with EU regulations or National regulations.

16. Other information
Label Requirements

To the best of our knowledge this substance/preparation is not classified as hazardous according to EU, US or any other known national regulations.

: MAY BE HARMFUL IF SWALLOWED.
Health Fire Hazard Reactivity Personal Protection

9.

Physical and chemical properties
: Liquid. : Not available.

Hazardous Material Information System (U.S.A.)

1 0 0 B

National Fire Protection Association (U.S.A.)

0
Health

Fire Hazard

Physical state Colour

1

0

Reactivity Specific Hazard

16. Other information
Notice to Reader

References Other Special Considerations

: Not available. : Not available.
: 4 March 2003 : 25 February 2003 : No Previous Validation : 1 : Indicates information that has changed from previously issued version.

:

HISTORY
Date of printing Date of issue Date of Previous Issue Version

To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. This is not an MSDS. According to EU and US regulations we are not required to supply an MSDS for a product which is not classified as hazardous.

Notice to Reader

To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
Version

Date of issue

24 February 2003

Version 1

Page: 1/1

1

Page: 4/4

Material Safety Data Sheet
Endogen Standards

Endogen Standards

2.

Hazards identification
: : : : : No specific data. No specific data. No specific data. No specific data. None known.

1.

Product and company identification
: Endogen Standards : Thermo Fisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 or 800.874.3723 Manufacturer : Thermo Fisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 800.874.3723

Product name Supplier

Inhalation Ingestion Skin Eyes Medical conditions aggravated by overexposure

Product No.

MSDS # Validation date Print date Responsible name In case of emergency

: 1856475 1856479 1856544 1856559 1856585 1856588 1856790 1856793 1856846 1856850 1856920 1856931 1856998 1857000 1857055 1857059 1857134 1857152 1857180 1857183 1857422 1857425 1890365 1890367 : 7096 : 7/30/2008. : 7/30/2008. : MSDS (Regulatory Affairs) : CHEMTREC: Use of : Refer to the instruction booklet for proper and intended use. 800.424.9300 Substance/Preparation Otherwise, contact supplier for OUTSIDE US: specific applications. 202.483.7616

The preparation is not classified as dangerous according to Directive 1999/45/EC and its amendments. Classification : Not classified. See toxicological information (section 11)

3.

Composition/information on ingredients

Substance/preparation : Preparation There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section.

4.

First aid measures
: Move exposed person to fresh air. Keep person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. Get medical attention if symptoms occur. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. : Wash out mouth with water. Remove dentures if any. Move exposed person to fresh air. Keep person warm and at rest. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Get medical attention if symptoms occur. Never give anything by mouth to an unconscious person. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. : Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur. Wash clothing before reuse. Clean shoes thoroughly before reuse. : Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs. : No action shall be taken involving any personal risk or without suitable training.

Inhalation

2.

Hazards identification
: Liquid. [Clear sparkling liquid.] : While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product. : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. No known significant effects or critical hazards. Avoid prolonged contact with eyes, skin and clothing. : Eye contact. Inhalation. Ingestion. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. Contains material which does not cause damage to the following organs: central nervous system (CNS). Ingestion

Physical state OSHA/HCS status

Emergency overview

Routes of entry Potential acute health effects Inhalation : Ingestion : : Skin : Eyes Potential chronic health effects Chronic effects : Carcinogenicity : Mutagenicity : Teratogenicity : Developmental effects : Fertility effects : Target organs :

Skin contact

Eye contact

Protection of first-aiders See section 11 for more detailed information on health effects and symptoms.

5.

Fire-fighting measures
: In a fire or if heated, a pressure increase will occur and the container may burst. : Use an extinguishing agent suitable for the surrounding fire. : None known. : Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. 2/7

Flammability of the product Extinguishing media Suitable Not suitable Special exposure hazards

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5.

Fire-fighting measures
: No specific data. : Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

8.

Exposure controls/personal protection
: No special ventilation requirements. Good general ventilation should be sufficient to control worker exposure to airborne contaminants. If this product contains ingredients with exposure limits, use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure below any recommended or statutory limits. : Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location. : Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator. : Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. : Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts. : Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product. : Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

Hazardous combustion products Special protective equipment for fire-fighters

Engineering measures

6.

Accidental release measures
: No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). : Stop leak if without risk. Move containers from spill area. Approach release from upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash spillages into an effluent treatment plant or proceed as follows. Contain and collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or diatomaceous earth and place in container for disposal according to local regulations (see section 13). Dispose of via a licensed waste disposal contractor. Contaminated absorbent material may pose the same hazard as the spilled product. Note: see section 1 for emergency contact information and section 13 for waste disposal. : Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water-soluble or absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor.

Hygiene measures

Personal precautions

Environmental precautions

Personal protection Respiratory

Large spill

Hands

Eyes

Skin

Small spill

7.

Handling and storage
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous. Do not reuse container. : Do not store above the following temperature: -20°C (-4°F). Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

Environmental exposure controls

Handling

9.

Physical and chemical properties
: Liquid. [Clear sparkling liquid.] : Colorless to light yellow. : Easily soluble in the following materials: cold water and hot water.

Physical state Color Solubility

Storage

10 . Stability and reactivity
Chemical stability Conditions to avoid Incompatible materials Hazardous decomposition products Possibility of hazardous reactions : The product is stable. Under normal conditions of storage and use, hazardous polymerization will not occur. : No specific data. : No specific data. : Under normal conditions of storage and use, hazardous decomposition products should not be produced. : Will not occur.

8.

Exposure controls/personal protection

Europe No exposure limit value known. Consult local authorities for acceptable exposure limits. Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace atmosphere or biological monitoring may be required to determine the effectiveness of the ventilation procedures or other control measures and/or the necessity to use respiratory protective equipment.

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11 . Toxicological information
United States Acute toxicity Conclusion/Summary Chronic toxicity Conclusion/Summary Carcinogenicity Conclusion/Summary Mutagenicity Conclusion/Summary Teratogenicity Conclusion/Summary Reproductive toxicity Conclusion/Summary Europe Chronic effects Carcinogenicity Mutagenicity Teratogenicity Developmental effects Fertility effects : : : : : : No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. : Not available. : Not available. : Not available. : Not available. : Not available. : Not available.

14 . Transport information
Regulatory information DOT Classification IATA-DGR Class PG* : Packing group UN number Not regulated. Proper shipping name Classes Not available. PG* -

Not available. Not available.

15 . Regulatory information
United States HCS Classification U.S. Federal regulations : Not regulated. : TSCA 8(a) IUR: sucrose United States inventory (TSCA 8b): All components are listed or exempted. SARA 302/304/311/312 extremely hazardous substances: No products were found. SARA 302/304 emergency planning and notification: No products were found. SARA 302/304/311/312 hazardous chemicals: No products were found. SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found. Clean Water Act (CWA) 307: No products were found. Clean Water Act (CWA) 311: sodium phosphate, dibasic Clean Air Act (CAA) 112 accidental release prevention: No products were found. Clean Air Act (CAA) 112 regulated flammable substances: No products were found. Clean Air Act (CAA) 112 regulated toxic substances: No products were found. Canada WHMIS (Canada) Canadian lists : Not controlled under WHMIS (Canada). : CEPA Toxic substances: None of the components are listed. Canadian ARET: None of the components are listed. Canadian NPRI: None of the components are listed. Alberta Designated Substances: None of the components are listed. Ontario Designated Substances: None of the components are listed. Quebec Designated Substances: None of the components are listed. : Canada inventory: Not determined. : This product is not classified according to EU legislation. : : Australia inventory (AICS): All components are listed or exempted. China inventory (IECSC): All components are listed or exempted. Korea inventory (KECI): All components are listed or exempted. Philippines inventory (PICCS): All components are listed or exempted. Japan inventory (ENCS): Not determined.

12 . Ecological information
Environmental effects United States Aquatic ecotoxicity Conclusion/Summary Other adverse effects : No known significant effects or critical hazards.

: Not available. : No known significant effects or critical hazards.

13 . Disposal considerations
Waste disposal : The generation of waste should be avoided or minimized wherever possible. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Canada inventory EU regulations Risk phrases International regulations International lists

: Within the present knowledge of the supplier, this product is not regarded as hazardous waste, as defined by EU Directive 91/689/EEC. Disposal should be in accordance with applicable regional, national and local laws and regulations. Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION for additional handling information and protection of employees. Hazardous waste

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16 . Other information
Label requirements Hazardous Material Information System (U.S.A.) : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. : Health Flammability Physical hazards 0 0 0

The customer is responsible for determining the PPE code for this material. National Fire Protection : Association (U.S.A.) 0 Health 0 0 Flammability Instability Special : 7/30/2008. : 7/30/2008. Date of issue : 7/29/2008. Date of previous issue Version : 2.03 Indicates information that has changed from previously issued version. Notice to reader To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.

Date of printing

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