Notice of Grant of Stock Option

							                                        FORM 11

 NOTICE OF PROPOSED STOCK OPTION GRANT OR AMENDMENT -
                       AMENDED

Name of CNQ Issuer: Biosign Technologies Inc. (the “Issuer”).

Trading Symbol: BIOS

Date: November 29, 2006

This CNQ Form 11 is being re-filed to include options which were granted to an
employee but were not included in the original filing dated November 27, 2006.

Yours very truly,
Kevin Gilbride
Chief Financial Officer and Corporate Secretary


1.       New Options Granted:

Date of Grant: November 27, 2006

       Position (Director/
            Officer/
     Employee/ Consultant/                                                        No. of Options
     Management Company                                                           Granted in Past
                             Insider    No. of                                      12 Months
                             Yes or    Optioned      Exercise       Expiry Date      (including
                               No?      Shares        Price                        current grant)
         4 Consultants         No        255,000            $1.00     November            335,000
                                                                       27, 2009
          1 Employee           No         50,000            $1.00     November            200,000
                                                                       27, 2016
                                         305,000

Total Number of optioned shares proposed for acceptance: 305,000.




                    FORM 11 – NOTICE OF PROPOSED STOCK OPTION GRANT
                                      OR AMENDMENT
                                       September 09, 2003
                                            Page 1
2.      Other Presently Outstanding Options:


                               No. of Optioned       Exercise      Original Date
     Name of Optionee             Shares(1)           Price          of Grant       Expiry Date
 Officers/Management
 Richard Potts                          600,000       $1.00         July 17, 2006   July 14, 2016
 Radu Leca                              400,000       $1.00         July 17, 2006   July 14, 2016
 Kevin Gilbride                         180,000       $1.00         July 17, 2006   July 14, 2016
 Eva Kettle                             180,000       $1.00         July 17, 2006   July 14, 2016
 Directors
 Suresh Kumar                           150,000       $1.00         July 17, 2006   July 14, 2016
 Jeffrey Puritt                         150,000       $1.00         July 17, 2006   July 14, 2016
 David Silver                           150,000       $1.00         July 17, 2006   July 14, 2016


 Employees                              465,000       $1.00         July 17, 2006   July 14, 2016


 Consultants                            440,000       $1.00         July 17, 2006   July 14, 2011
 Consultants                            315,000       $1.00         July 17, 2006   July 14, 2009


                                      3,030,000

(1) Set out number of optioned shares for each grant with different terms.


3.            Additional Information

      (a)     If shareholder approval was required for the grant of options (including prior
              approval of a stock option plan), state the date that the shareholder meeting
              approving the grant was or will be held.

              Adoption and approval of Share Option Plan at the meeting of
              shareholders on June 30, 2006

      (b)     State the date of the news release announcing the grant of options.

              None




                     FORM 11 – NOTICE OF PROPOSED STOCK OPTION GRANT
                                       OR AMENDMENT
                                            September 09, 2003
                                                 Page 2
(c)   State the total issued and outstanding share capital at the date of grant or
      amendment.

      The total share capital issued and outstanding at November 27, 2006
      prior to the option grant dated November 27, 2006 was:

         Common shares                              57,497,373
         Common share warrants (exercisable @$1.00)    269,896
         Common share options (exercisable @$1.00)   3,030,000

(d)   State, as a percentage of the issued and outstanding shares of the Issuer
      indicated in (c) above, the aggregate number of shares that are subject to
      incentive stock options, including new options, amended options and other
      presently outstanding options.

      The aggregate number of shares that are subject to share warrants and
      share options are:

         Common share warrants (269,896)                              0.4%
         Common share options (3,335,000)                             5.5%

(e)   If the new options are being granted pursuant to a stock option plan, state the
      number of remaining shares reserved for issuance under the plan.

      Total # of options reserved for issuance (10%)              5,749,737

      Total granted                                               3,335,000

      Remaining pool available                                    2,414,737

(f)   If the Issuer has completed a public distribution of its securities within 90 days
      of the date of grant, state the per share price paid by the public investors.

      The Issuer completed a reverse takeover transaction and a private
      placement on July 14, 2006 as described in the Management Information
      Circular dated May 31, 2006. The price paid per share on a comparable
      basis was $1.00 per share.

(g)   Describe the particulars of any proposed material changes in the affairs of the
      Issuer.

      None




             FORM 11 – NOTICE OF PROPOSED STOCK OPTION GRANT
                               OR AMENDMENT
                                  September 09, 2003
                                       Page 3
4.        Certificate of Compliance

The undersigned hereby certifies that:

1.        The undersigned is a director and/or senior officer of the Issuer and has been
          duly authorized by a resolution of the board of directors of the Issuer to sign
          this Certificate of Compliance.

2.        As of the date hereof there is no material information concerning the Issuer
          which has not been publicly disclosed.

3.        The undersigned hereby certifies to CNQ that the Issuer is in compliance with
          the requirements of applicable securities legislation (as such term is defined
          in National Instrument 14-101) and all CNQ Requirements (as defined in CNQ
          Policy 1).

4.        All of the information in this Form 11 Notice of Proposed Stock Option Grant
          or Amendment is true.


Dated November 29, 2006




                                                          Kevin Gilbride

                                                          Chief Financial Officer &
                                                          Corporate Secretary




                 FORM 11 – NOTICE OF PROPOSED STOCK OPTION GRANT
                                   OR AMENDMENT
                                     September 09, 2003
                                          Page 4