CT-GUIDED RF ABLATION IN THE MANAGEMENT OF METASTATIC LIVER DISEASE IN PANCREATIC CARCINOMA PATIENTS S Mylona, D Gavrilou, A Lourbakou, N Karampas, N Lepida, N Batakis HELLENIC RED CROSS HOSPITAL Purpose: To present our experience in RF ablation of aa b metastatic liver disease in patients after surgical treated b pancreatic carcinoma. Material and methods: In a 7 year period 30 patients underwent CT-guided RF ablation for the management of metastatic liver disease from pancreatic carcinoma. Twenty/30 of them had only one liver lesion, 8/30 had Fig. 1: a) RF ablation of a metastasis to the right lobe of the liver from two lesions and 2/30 patients had 3 lesions. Forty eight RFA sessions were performed totally for 42 liver adenocarcinoma of the pancreas, b) one month follow-up shows total necrosis lesions, under local anesthesia. An analgesic treatment of the lesion 45 min before the procedure was received. a b The mean ablation time was 15 minutes (11-18 min). a b Follow-up was performed in 1-3-6-12 months and at 6m ever after. Results: The 1st month imaging follow-up showed total necrosis in 37/42 of the lesions (technical success 88%) (fig 1, 2). Five/42 (12%) tumors had partial Fig. 2: a) RF ablation of a hepatic metastasis from neuroendocrine tumor of necrosis and a second session was followed, which led the pancreas, b) total necrosis of the lesion in one month follow-up to total necrosis (fig 3). a b c The six month follow-up revealed multiple hepatic lesions in 5/30 patients. Twelve months after the first RFA session 3/30 patients a b presented with a new lesion that treated with RFA too. No complications were observed. Conclusion: In case of patients with pancreatic carcinoma Fig. 3: a) RF ablation of a metastasis to the left lobe of the liver from deal with operation and metastatic liver disease, CT- adenocarcinoma of the pancreas, b) one month follow-up shows partial guided RFA is a minimally invasive, acceptable, well necrosis, c) a second RF ablation led to total necrosis of the lesion tolerated alternative treatment. References: 1. Tumor Ablation with Radio-frequency Energy, G. Scott Gazelle, S. Nahum Goldberg, Luigi Solbiati, and Tito Livraghi, Radiology, Dec 2000; 217: 633. 2. Percutaneous Radio-frequency Ablation of Hepatic Metastases from Colorectal Cancer: Long-term Results in 117 Patients, Luigi Solbiati, Tito Livraghi, S. Nahum Goldberg, Tiziana Ierace, Franca Meloni, Marina Dellanoce, Luca Cova, Elkan F. Halpern, and G. Scott Gazelle, Radiology, Oct 2001; 221: 159. 3. Radio-frequency Ablation of Liver Tumors: Assessment of Therapeutic Response and Complications, Haesun Choi, Evelyne M. Loyer, Ronelle A. DuBrow, Harmeet Kaur, Cynthia L. David, Steven Huang, Steven Curley, and Chusilp Charnsangavej, RadioGraphics, Oct 2001; 21: S41 - S54.
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